1 |
ERBB3 | parental protein | 146 | 0.053 | 15384.455 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
2 |
ABL1 | oncoprotein | 25 | 0.428 | 67.541 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding SH3_1 (PF00018, IPR001452, SM00326): SH3 domain FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2 |
3 |
ABL2 | oncoprotein | 15 | 0.505 | 18.670 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding SH3_1 (PF00018, IPR001452, SM00326): SH3 domain NHS (PF15273, IPR024845): NHS-like |
4 |
ACTA1 | interactor | 7 | 0.476 | 5.956 | Actin (PF00022, IPR004000, SM00268): Actin |
5 |
ACTA2 | interactor | 3 | 0.667 | 1.000 | Actin (PF00022, IPR004000, SM00268): Actin |
6 |
ACTB | oncoprotein | 16 | 0.390 | 28.752 | Actin (PF00022, IPR004000, SM00268): Actin |
7 |
ACTBL2 | interactor | 3 | 1.000 | 0 | Actin (PF00022, IPR004000, SM00268): Actin |
8 |
ACTC1 | interactor | 2 | 1.000 | 0 | Actin (PF00022, IPR004000, SM00268): Actin |
9 |
ACTG1 | protein found in more fusions | 12 | 0.491 | 17.548 | Actin (PF00022, IPR004000, SM00268): Actin |
10 |
ACTG2 | interactor | 1 | 0 | 0 | Actin (PF00022, IPR004000, SM00268): Actin |
11 |
AIFM1 | oncoprotein | 4 | 1.000 | 0 | Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term AIF-MLS (PF14962, IPR032773): Mitochondria Localisation Sequence |
12 |
AKT1 | oncoprotein | 21 | 0.321 | 74.594 | PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
13 |
ANXA2 | interactor | 4 | 0.667 | 2.000 | Annexin (PF00191, IPR018502, SM00335): Annexin |
14 |
AP1M2 | interactor | 2 | 1.000 | 0 | Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain |
15 |
ATP5A1 | protein found in more fusions | 10 | 0.556 | 8.519 | ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C (PF00306, IPR000793): ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain |
16 |
B2M | oncoprotein | 5 | 0.667 | 1.333 | C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain |
17 |
B3GLCT | interactor | 1 | 0 | 0 | Fringe (PF02434, IPR003378): Fringe-like |
18 |
BCAR3 | oncoprotein | 2 | 1.000 | 0 | RasGEF (PF00617, IPR001895, SM00147): RasGEF domain SH2 (PF00017, IPR000980, SM00252): SH2 domain |
19 |
C1QBP | interactor | 13 | 0.308 | 44.450 | MAM33 (PF02330, IPR003428): Mitochondrial glycoprotein DUF3053 (PF11254, IPR021413): Protein of unknown function (DUF3053) |
20 |
CANX | interactor | 7 | 0.619 | 4.006 | Calreticulin (PF00262, IPR001580): Calreticulin family DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit |
21 |
CD82 | suppressor | 4 | 0.667 | 0.515 | Tetraspannin (PF00335, IPR018499): Tetraspanin family |
22 |
CDC37 | protein found in more fusions | 22 | 0.295 | 98.570 | CDC37_C (PF08564, IPR013873, SM01069): Cdc37 C terminal domain CDC37_M (PF08565, IPR013874, SM01070): Cdc37 Hsp90 binding domain CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding Rho_Binding (PF08912, IPR015008): Rho Binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding |
23 |
CHN2 | interactor | 1 | 0 | 0 | RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain SH2 (PF00017, IPR000980, SM00252): SH2 domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4127 (PF13552, IPR025394): Protein of unknown function (DUF4127) |
24 |
CRK | oncoprotein | 24 | 0.409 | 68.500 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
25 |
CRKL | oncoprotein | 12 | 0.652 | 13.825 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
26 |
CSK | interactor | 9 | 0.611 | 6.397 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
27 |
DAB1 | interactor | 2 | 1.000 | 0 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) |
28 |
DAPP1 | interactor | 3 | 0.667 | 0.400 | PH (PF00169, IPR001849, SM00233): PH domain SH2 (PF00017, IPR000980, SM00252): SH2 domain |
29 |
DNAJA1 | interactor | 9 | 0.806 | 2.732 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain |
30 |
DNAJB11 | interactor | 8 | 0.679 | 6.533 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain |
31 |
DPPA4 | interactor | 6 | 0.600 | 2.567 | Ribosomal_L40e (PF01020, IPR001975): Ribosomal L40e family DCR (PF14047, IPR025891): Dppa2/4 conserved region Dppa2_A (PF14049, IPR025892): Dppa2/4 conserved region in higher vertebrates |
32 |
EGF | oncoprotein | 4 | 1.000 | 0 | EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain SGL (PF08450, IPR013658): SMP-30/Gluconolaconase/LRE-like region Ldl_recept_b (PF00058, IPR000033, SM00135): Low-density lipoprotein receptor repeat class B cEGF (PF12662, IPR026823): Complement Clr-like EGF-like EGF_3 (PF12947, IPR024731): EGF domain FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site DUF5050 (PF16472, IPR032485): Domain of unknown function (DUF5050) |
33 |
EGFR | oncoprotein | 69 | 0.142 | 1456.956 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
34 |
EGR1 | suppressor | 2 | 1.000 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type DUF3432 (PF11914, IPR021839): Domain of unknown function (DUF3432) DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
35 |
EIF1AX | oncoprotein | 1 | 0 | 0 | eIF-1a (PF01176, IPR006196): Translation initiation factor 1A / IF-1 |
36 |
ERBB2 | oncoprotein | 44 | 0.203 | 472.480 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
37 |
FER | protein found in more fusions | 9 | 0.750 | 1.688 | DivIC (PF04977, IPR007060): Septum formation initiator FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain Glyco_transf_28 (PF03033, IPR004276): Glycosyltransferase family 28 N-terminal domain PEP-utilisers_N (PF05524, IPR008731): PEP-utilising enzyme, N-terminal Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain Med29 (PF11568, IPR021018): Mediator complex subunit 29 |
38 |
FGFR1 | oncoprotein | 13 | 0.439 | 12.783 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
39 |
GFAP | protein found in more fusions | 7 | 0.733 | 0.645 | Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region |
40 |
GRB2 | oncoprotein | 48 | 0.226 | 512.048 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093) |
41 |
GRB7 | interactor | 2 | 1.000 | 0 | BPS (PF08947, IPR015042): BPS (Between PH and SH2) PH (PF00169, IPR001849, SM00233): PH domain RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain SH2 (PF00017, IPR000980, SM00252): SH2 domain |
42 |
HBA1 | interactor | 3 | 0.667 | 0.667 | Globin (PF00042, IPR000971): Globin |
43 |
HBB | interactor | 3 | 0.667 | 0.667 | Globin (PF00042, IPR000971): Globin |
44 |
HBD | interactor | 3 | 0.667 | 1.000 | Globin (PF00042, IPR000971): Globin |
45 |
HBE1 | interactor | 1 | 0 | 0 | Globin (PF00042, IPR000971): Globin |
46 |
HBG1 | interactor | 1 | 0 | 0 | Globin (PF00042, IPR000971): Globin |
47 |
HBG2 | interactor | 2 | 0 | 0 | Globin (PF00042, IPR000971): Globin |
48 |
HCK | oncoprotein | 12 | 0.485 | 12.293 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
49 |
HDAC6 | oncoprotein | 13 | 0.561 | 9.929 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain PSGP (PF07276, IPR009900): Apopolysialoglycoprotein (PSGP) zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein |
50 |
HLA-A | oncoprotein | 5 | 0.500 | 4.000 | DUF202 (PF02656, IPR003807): Domain of unknown function (DUF202) MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2 MHC_I_C (PF06623, IPR010579): MHC_I C-terminus C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain |
51 |
HLA-B | oncoprotein | 5 | 0.667 | 1.333 | MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2 MHC_I_C (PF06623, IPR010579): MHC_I C-terminus C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain |
52 |
HLA-DPA1 | interactor | 4 | 0.500 | 2.667 | MHC_II_alpha (PF00993, IPR001003, SM00920): Class II histocompatibility antigen, alpha domain C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain C1-set_C (PF16196, IPR032431): C1-set C-terminal domain |
53 |
HNRNPA2B1 | oncoprotein | 11 | 0.491 | 19.700 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
54 |
HNRNPAB | interactor | 6 | 0.600 | 6.000 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain GRP (PF07172, IPR010800): Glycine rich protein family NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2462 (PF09495, IPR019034): Protein of unknown function (DUF2462) |
55 |
HNRNPF | interactor | 7 | 0.762 | 3.500 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spot_14 (PF07084, IPR009786): Thyroid hormone-inducible hepatic protein Spot 14 zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
56 |
HNRNPH1 | oncoprotein | 9 | 0.667 | 6.133 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
57 |
HNRNPH2 | interactor | 10 | 0.500 | 14.900 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
58 |
HNRNPH3 | protein found in more fusions | 7 | 1.000 | 0 | Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
59 |
HSP90AA1 | oncoprotein | 31 | 0.333 | 161.192 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
60 |
HSP90AB1 | oncoprotein | 19 | 0.588 | 18.734 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
61 |
HSPA1A | interactor | 16 | 0.542 | 29.809 | HSP70 (PF00012, IPR013126): Hsp70 protein |
62 |
HSPA5 | oncoprotein | 33 | 0.270 | 250.980 | HSP70 (PF00012, IPR013126): Hsp70 protein |
63 |
HSPA8 | oncoprotein | 24 | 0.413 | 82.963 | HSP70 (PF00012, IPR013126): Hsp70 protein |
64 |
IL6ST | oncoprotein | 9 | 0.722 | 3.283 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain IL6Ra-bind (PF09240, IPR015321): Interleukin-6 receptor alpha chain, binding Lep_receptor_Ig (PF06328, IPR010457): Ig-like C2-type domain Pur_ac_phosph_N (PF16656, IPR015914): Purple acid Phosphatase, N-terminal domain |
65 |
ITK | oncoprotein | 9 | 0.857 | 0.748 | BTK (PF00779, IPR001562, SM00107): BTK motif PH (PF00169, IPR001849, SM00233): PH domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
66 |
JAK2 | oncoprotein | 17 | 0.567 | 25.218 | FERM_M (PF00373, IPR019748): FERM central domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain |
67 |
JAK3 | oncoprotein | 3 | 0.667 | 0.667 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain |
68 |
LGALS3BP | oncoprotein | 14 | 0.538 | 19.652 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain SRCR_2 (PF15494, IPR017448): Scavenger receptor cysteine-rich domain |
69 |
LRIG1 | suppressor | 4 | 0.833 | 0.500 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRR_2 (PF07723, IPR013101): Leucine Rich Repeat LRRCT (PF01463, IPR000483, SM00082): Leucine rich repeat C-terminal domain LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat Ig_3 (PF13927): Immunoglobulin domain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
70 |
LRPPRC | interactor | 4 | 0.833 | 0.500 | DED (PF01335, IPR001875, SM00031): Death effector domain MA3 (PF02847, IPR003891, SM00544): MA3 domain PPR (PF01535, IPR002885): PPR repeat TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat ApoB100_C (PF12491, IPR022176): Apolipoprotein B100 C terminal PPR_2 (PF13041, IPR002885): PPR repeat family PPR_3 (PF13812, IPR002885): Pentatricopeptide repeat domain TPR_19 (PF14559): Tetratricopeptide repeat PPR_long (PF17177): Pentacotripeptide-repeat region of PROPR |
71 |
MASP1 | interactor | 3 | 0.667 | 0.400 | CUB (PF00431, IPR000859, SM00042): CUB domain Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat) Trypsin (PF00089, IPR001254, SM00020): Trypsin FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site |
72 |
MDM2 | oncoprotein | 20 | 0.304 | 76.283 | Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
73 |
MRPS14 | interactor | 3 | 1.000 | 0 | Ribosomal_S14 (PF00253, IPR001209): Ribosomal protein S14p/S29e |
74 |
MRPS17 | interactor | 1 | 0 | 0 | Ribosomal_S17 (PF00366, IPR000266): Ribosomal protein S17 |
75 |
MRPS18B | interactor | 7 | 0.619 | 5.567 | Ribosomal_S18 (PF01084, IPR001648): Ribosomal protein S18 HTH_21 (PF13276, IPR025948): HTH-like domain zf-RING_10 (PF16685, IPR032043): zinc RING finger of MSL2 |
76 |
MRPS22 | interactor | 10 | 0.556 | 12.200 | MRP-S22 (PF10245, IPR019374): Mitochondrial 28S ribosomal protein S22 |
77 |
MRPS23 | interactor | 5 | 0.900 | 0.400 | MRP-S23 (PF10484, IPR023611): Mitochondrial ribosomal protein S23 |
78 |
MRPS25 | interactor | 5 | 0.700 | 2.000 | L51_S25_CI-B8 (PF05047, IPR007741, SM00916): Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain |
79 |
MRPS26 | interactor | 5 | 0.900 | 0.333 | MRP-S26 (PF14943, IPR026140): Mitochondrial ribosome subunit S26 |
80 |
MRPS27 | interactor | 5 | 0.900 | 0.400 | MRP-S27 (PF10037, IPR019266): Mitochondrial 28S ribosomal protein S27 |
81 |
MRPS28 | interactor | 7 | 0.762 | 2.300 | MRP-S35 (PF10246, IPR019375): Mitochondrial ribosomal protein MRP-S35 |
82 |
MRPS34 | interactor | 4 | 0.500 | 2.333 | MRP-S34 (PF16053, IPR032053): Mitochondrial 28S ribosomal protein S34 |
83 |
MUC1 | oncoprotein | 7 | 0.762 | 5.000 | SEA (PF01390, IPR000082, SM00200): SEA domain Shisa (PF13908, IPR026910): Wnt and FGF inhibitory regulator Collectrin (PF16959, IPR031588): Renal amino acid transporter |
84 |
NANOG | interactor | 7 | 0.400 | 6.500 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
85 |
NCK1 | oncoprotein | 13 | 0.462 | 18.952 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain |
86 |
NCK2 | interactor | 8 | 0.524 | 6.152 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain |
87 |
NEDD4 | suppressor | 10 | 0.611 | 4.366 | Rota_NS26 (PF01525, IPR002512): Rotavirus NS26 WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
88 |
NRG1 | interactor | 3 | 1.000 | 0 | EGF (PF00008, IPR000742, SM00181): EGF-like domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain Neuregulin (PF02158, IPR002154): Neuregulin family |
89 |
NRG2 | interactor | 1 | 0 | 0 | EGF (PF00008, IPR000742, SM00181): EGF-like domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain Neuregulin (PF02158, IPR002154): Neuregulin family CiPC (PF15800, IPR031602): Clock interacting protein circadian |
90 |
ODF2L | interactor | 1 | 0 | 0 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) ZapB (PF06005, IPR009252): Cell division protein ZapB DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5 RNA_bind_2 (PF10133, IPR019300): Predicted RNA-binding protein SOGA (PF11365, IPR027881): Protein SOGA DUF4107 (PF13389, IPR025180): Protein of unknown function (DUF4107) ABC_tran_CTD (PF16326, IPR032524): ABC transporter C-terminal domain |
91 |
PA2G4 | interactor | 6 | 0.600 | 3.900 | Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24 Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein TraC (PF07820, IPR012930): TraC-like protein |
92 |
PCGF1 | interactor | 6 | 0.500 | 2.900 | zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
93 |
PDF | interactor | 1 | 0 | 0 | Pep_deformylase (PF01327, IPR023635): Polypeptide deformylase |
94 |
PHLDA1 | oncoprotein | 2 | 1.000 | 0 | Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region PH (PF00169, IPR001849, SM00233): PH domain Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) TonB_N (PF16031): TonB N-terminal region |
95 |
PIK3CA | oncoprotein | 7 | 0.714 | 1.610 | PI3K_C2 (PF00792, IPR002420, SM00142): Phosphoinositide 3-kinase C2 PI3K_p85B (PF02192, IPR003113, SM00143): PI3-kinase family, p85-binding domain PI3K_rbd (PF00794, IPR000341, SM00144): PI3-kinase family, ras-binding domain PI3Ka (PF00613, IPR001263, SM00145): Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF2321 (PF10083, IPR016891): Uncharacterized protein conserved in bacteria (DUF2321) PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase |
96 |
PIK3CB | oncoprotein | 9 | 0.694 | 2.995 | PI3K_C2 (PF00792, IPR002420, SM00142): Phosphoinositide 3-kinase C2 PI3K_p85B (PF02192, IPR003113, SM00143): PI3-kinase family, p85-binding domain PI3K_rbd (PF00794, IPR000341, SM00144): PI3-kinase family, ras-binding domain PI3Ka (PF00613, IPR001263, SM00145): Phosphoinositide 3-kinase family, accessory domain (PIK domain) RWD (PF05773, IPR006575, SM00591): RWD domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase Tom37_C (PF11801, IPR019564): Tom37 C-terminal domain DUF4381 (PF14316, IPR025489): Domain of unknown function (DUF4381) |
97 |
PIK3R1 | oncoprotein | 24 | 0.443 | 63.503 | RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain |
98 |
PIK3R2 | oncoprotein | 17 | 0.603 | 16.914 | RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain |
99 |
PIK3R3 | interactor | 13 | 0.603 | 10.528 | SH2 (PF00017, IPR000980, SM00252): SH2 domain PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain |
100 |
PLCG1 | oncoprotein | 16 | 0.567 | 17.113 | C2 (PF00168, IPR000008, SM00239): C2 domain PH (PF00169, IPR001849, SM00233): PH domain SH2 (PF00017, IPR000980, SM00252): SH2 domain PI-PLC-X (PF00388, IPR000909, SM00148): Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y (PF00387, IPR001711, SM00149): Phosphatidylinositol-specific phospholipase C, Y domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain PH_12 (PF16457, IPR001849): Pleckstrin homology domain |
101 |
PON2 | interactor | 5 | 0.800 | 1.167 | Arylesterase (PF01731, IPR002640): Arylesterase |
102 |
POTEE | interactor | 1 | 0 | 0 | Actin (PF00022, IPR004000, SM00268): Actin DUF3641 (PF12345, IPR024521): Protein of unknown function (DUF3641) Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) CCDC144C (PF14915): CCDC144C protein coiled-coil region |
103 |
POTEF | oncoprotein | 1 | 0 | 0 | Actin (PF00022, IPR004000, SM00268): Actin Toxin_16 (PF07945, IPR012499): Janus-atracotoxin Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) CCDC144C (PF14915): CCDC144C protein coiled-coil region |
104 |
POTEKP | interactor | 1 | 0 | 0 | NA |
105 |
POU5F1 | oncoprotein | 13 | 0.227 | 39.669 | Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
106 |
PTCD3 | interactor | 8 | 0.536 | 8.800 | PPR (PF01535, IPR002885): PPR repeat PPR_2 (PF13041, IPR002885): PPR repeat family PPR_3 (PF13812, IPR002885): Pentatricopeptide repeat domain |
107 |
PTK6 | interactor | 6 | 0.800 | 0.367 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
108 |
PTPN11 | suppressor | 11 | 0.822 | 2.162 | SH2 (PF00017, IPR000980, SM00252): SH2 domain Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase |
109 |
RAE1 | interactor | 3 | 0.667 | 0.250 | Exonuc_X-T_C (PF08411, IPR013620): Exonuclease C-terminal WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
110 |
RASA1 | oncoprotein | 11 | 0.709 | 4.900 | C2 (PF00168, IPR000008, SM00239): C2 domain PH (PF00169, IPR001849, SM00233): PH domain RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
111 |
RGS4 | interactor | 2 | 1.000 | 0 | RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain |
112 |
RIN1 | interactor | 4 | 1.000 | 0 | RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain SH2 (PF00017, IPR000980, SM00252): SH2 domain VPS9 (PF02204, IPR003123, SM00167): Vacuolar sorting protein 9 (VPS9) domain |
113 |
RNF41 | interactor | 2 | 0 | 0 | Sina (PF03145, IPR018121): Seven in absentia protein family USP8_interact (PF08941, IPR015036): USP8 interacting zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
114 |
RPL23 | interactor | 14 | 0.242 | 53.318 | Ribosomal_L14 (PF00238, IPR000218): Ribosomal protein L14p/L23e |
115 |
RPN1 | oncoprotein | 8 | 0.464 | 9.133 | Ribophorin_I (PF04597, IPR007676): Ribophorin I CtIP_N (PF10482, IPR019518): Tumour-suppressor protein CtIP N-terminal domain |
116 |
RPS27 | interactor | 5 | 0.800 | 0.533 | Ribosomal_S27e (PF01667, IPR000592): Ribosomal protein S27 DUF3795 (PF12675, IPR024227): Protein of unknown function (DUF3795) |
117 |
RPS27A | interactor | 6 | 0.467 | 3.986 | DUF1049 (PF06305, IPR010445): Protein of unknown function (DUF1049) |
118 |
RPS27L | interactor | 6 | 0.667 | 2.533 | E7 (PF00527, IPR000148): E7 protein, Early protein Ribosomal_S27e (PF01667, IPR000592): Ribosomal protein S27 zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type DUF3382 (PF11862, IPR021807): Domain of unknown function (DUF3382) |
119 |
S100A10 | oncoprotein | 3 | 1.000 | 0 | S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
120 |
SH2B3 | suppressor | 6 | 0.800 | 1.467 | PH (PF00169, IPR001849, SM00233): PH domain Phe_ZIP (PF08916, IPR015012): Phenylalanine zipper SH2 (PF00017, IPR000980, SM00252): SH2 domain |
121 |
SH2D1A | interactor | 3 | 1.000 | 0 | SH2 (PF00017, IPR000980, SM00252): SH2 domain |
122 |
SHC1 | oncoprotein | 33 | 0.321 | 177.786 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) SH2 (PF00017, IPR000980, SM00252): SH2 domain |
123 |
SHC3 | interactor | 3 | 1.000 | 0 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) SH2 (PF00017, IPR000980, SM00252): SH2 domain |
124 |
SLC25A5 | interactor | 7 | 0.381 | 7.744 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
125 |
SLC25A6 | interactor | 3 | 0.667 | 0.154 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
126 |
SLC31A1 | interactor | 2 | 0 | 0 | Ctr (PF04145, IPR007274): Ctr copper transporter family |
127 |
SRC | oncoprotein | 24 | 0.423 | 59.364 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
128 |
SRPK2 | oncoprotein | 11 | 0.244 | 21.606 | DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Pkinase (PF00069, IPR000719): Protein kinase domain S-antigen (PF05756, IPR008825): S-antigen protein DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) |
129 |
SSR1 | interactor | 3 | 1.000 | 0 | TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit |
130 |
SYK | suppressor | 16 | 0.543 | 17.053 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain |
131 |
TNS2 | interactor | 5 | 0.600 | 1.586 | PTB (PF08416, IPR013625): Phosphotyrosine-binding domain SH2 (PF00017, IPR000980, SM00252): SH2 domain PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) cEGF (PF12662, IPR026823): Complement Clr-like EGF-like PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
132 |
TNS3 | interactor | 4 | 0.667 | 0.619 | PTB (PF08416, IPR013625): Phosphotyrosine-binding domain SH2 (PF00017, IPR000980, SM00252): SH2 domain PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal |
133 |
TNS4 | interactor | 3 | 1.000 | 0 | PTB (PF08416, IPR013625): Phosphotyrosine-binding domain SH2 (PF00017, IPR000980, SM00252): SH2 domain |
134 |
TUBA1B | interactor | 8 | 0.500 | 6.419 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
135 |
TUBA4A | interactor | 8 | 0.536 | 9.210 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
136 |
TUBB | interactor | 22 | 0.411 | 63.871 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
137 |
TUBB8 | interactor | 3 | 0.667 | 0.667 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
138 |
TUFM | interactor | 7 | 0.429 | 8.638 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
139 |
TXK | interactor | 2 | 1.000 | 0 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
140 |
UQCR10 | interactor | 1 | 0 | 0 | UCR_UQCRX_QCR9 (PF05365, IPR008027): Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like |
141 |
VAV1 | oncoprotein | 13 | 0.667 | 7.216 | PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH2 (PF00017, IPR000980, SM00252): SH2 domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 (PF00018, IPR001452, SM00326): SH3 domain CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain |
142 |
VAV2 | oncoprotein | 7 | 0.571 | 5.286 | PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain CotJB (PF12652, IPR024207): CotJB protein |
143 |
VAV3 | oncoprotein | 5 | 1.000 | 0 | PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain DUF2326 (PF10088, IPR018760): Uncharacterised protein conserved in bacteria (DUF2326) C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain PH_10 (PF15411): Pleckstrin homology domain |
144 |
YBEY | interactor | 2 | 1.000 | 0 | UPF0054 (PF02130, IPR002036): Uncharacterized protein family UPF0054 |
145 |
ZAP70 | interactor | 14 | 0.667 | 9.351 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain |
146 |
ZNF207 | interactor | 1 | 0 | 0 | MCPVI (PF02993, IPR004243): Minor capsid protein VI SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) zf-FCS (PF06467, IPR010507): MYM-type Zinc finger with FCS sequence motif zf-C2H2_4 (PF13894): C2H2-type zinc finger |