1 |
EPS15 | parental protein | 131 | 0.097 | 9575.082 | Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391) EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
2 |
ABL1 | oncoprotein | 18 | 0.493 | 25.246 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding SH3_1 (PF00018, IPR001452, SM00326): SH3 domain FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2 |
3 |
ACTB | oncoprotein | 18 | 0.529 | 22.375 | Actin (PF00022, IPR004000, SM00268): Actin |
4 |
AGFG1 | interactor | 5 | 0.700 | 0.833 | ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf |
5 |
AGFG2 | interactor | 3 | 0.667 | 0.333 | ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf |
6 |
ANLN | oncoprotein | 21 | 0.790 | 9.371 | Anillin (PF08174, IPR012966): Cell division protein anillin PH (PF00169, IPR001849, SM00233): PH domain Anillin_N (PF16018, IPR031970): Anillin N-terminus |
7 |
AP1B1 | interactor | 15 | 0.610 | 16.843 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain B2-adapt-app_C (PF09066, IPR015151, SM01020): Beta2-adaptin appendage, C-terminal sub-domain |
8 |
AP1G1 | interactor | 14 | 0.604 | 13.060 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain |
9 |
AP2A1 | interactor | 42 | 0.389 | 232.755 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region Alpha_adaptin_C (PF02296, IPR003164): Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain HEAT_2 (PF13646): HEAT repeats |
10 |
AP2A2 | interactor | 19 | 0.684 | 11.963 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region Alpha_adaptin_C (PF02296, IPR003164): Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain HEAT_2 (PF13646): HEAT repeats |
11 |
AP2B1 | interactor | 33 | 0.473 | 91.487 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain B2-adapt-app_C (PF09066, IPR015151, SM01020): Beta2-adaptin appendage, C-terminal sub-domain |
12 |
AP2M1 | protein found in more fusions | 67 | 0.234 | 951.654 | Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain |
13 |
AP2S1 | interactor | 15 | 0.562 | 14.798 | Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain |
14 |
AURKA | oncoprotein | 11 | 0.422 | 12.182 | Pkinase (PF00069, IPR000719): Protein kinase domain MTBP_C (PF14920, IPR029418): MDM2-binding |
15 |
BMP2K | interactor | 22 | 0.645 | 18.904 | Pkinase (PF00069, IPR000719): Protein kinase domain TCP (PF03634, IPR005333): TCP family transcription factor Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal EOS1 (PF12326, IPR021100): N-glycosylation protein BMP2K_C (PF15282, IPR028182): BMP-2-inducible protein kinase C-terminus PNRC (PF15365, IPR028322): Proline-rich nuclear receptor coactivator FAM60A (PF15396, IPR026065): Protein Family FAM60A |
16 |
CAPZA2 | interactor | 23 | 0.735 | 15.753 | F-actin_cap_A (PF01267, IPR002189): F-actin capping protein alpha subunit |
17 |
CCT3 | interactor | 10 | 0.578 | 8.918 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
18 |
CD4 | suppressor | 6 | 0.700 | 2.000 | ATP1G1_PLM_MAT8 (PF02038, IPR000272): ATP1G1/PLM/MAT8 family C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain CD4-extracel (PF09191, IPR015274): CD4, extracellular ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Tcell_CD4_C (PF12104, IPR021963): T cell CD4 receptor C terminal region |
19 |
CLINT1 | protein found in more fusions | 26 | 0.637 | 35.870 | ENTH (PF01417, IPR001026, SM00273): ENTH domain |
20 |
CLTB | interactor | 28 | 0.648 | 30.440 | Clathrin_lg_ch (PF01086, IPR000996): Clathrin light chain |
21 |
CLTC | oncoprotein | 40 | 0.418 | 198.573 | Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker Clathrin_propel (PF01394, IPR022365): Clathrin propeller repeat Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS Clathrin_H_link (PF13838): Clathrin-H-link |
22 |
CORO7 | interactor | 5 | 0.700 | 0.938 | DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_4 (PF16300): Type of WD40 repeat |
23 |
CRK | oncoprotein | 31 | 0.277 | 152.538 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
24 |
CRKL | oncoprotein | 6 | 0.867 | 0.515 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
25 |
DBN1 | oncoprotein | 29 | 0.631 | 46.581 | Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c |
26 |
DCAF1 | protein found in more fusions | 7 | 0.533 | 3.371 | DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) LisH (PF08513, IPR013720, SM00667): LisH ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated |
27 |
DNM2 | interactor | 10 | 0.578 | 6.043 | Dynamin_M (PF01031, IPR000375): Dynamin central region GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain PH (PF00169, IPR001849, SM00233): PH domain Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family |
28 |
EGFR | oncoprotein | 38 | 0.291 | 237.262 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
29 |
ELAVL1 | oncoprotein | 24 | 0.249 | 118.211 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
30 |
EPHA2 | oncoprotein | 13 | 0.606 | 8.897 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain |
31 |
EPN1 | interactor | 25 | 0.343 | 125.105 | ENTH (PF01417, IPR001026, SM00273): ENTH domain UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif |
32 |
EPN3 | interactor | 5 | 0.600 | 2.567 | ENTH (PF01417, IPR001026, SM00273): ENTH domain UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif |
33 |
FCHO2 | protein found in more fusions | 14 | 0.692 | 11.645 | DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain PIN_2 (PF10130, IPR002716): PIN domain muHD (PF10291, IPR018808): Muniscin C-terminal mu homology domain |
34 |
FLNA | suppressor | 29 | 0.574 | 52.296 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Filamin (PF00630, IPR017868): Filamin/ABP280 repeat |
35 |
FN1 | oncoprotein | 41 | 0.293 | 230.232 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
36 |
GAK | oncoprotein | 17 | 0.779 | 4.828 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain Pkinase (PF00069, IPR000719): Protein kinase domain PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein |
37 |
GJA1 | suppressor | 4 | 1.000 | 0 | Connexin43 (PF03508, IPR013124): Gap junction alpha-1 protein (Cx43) Connexin (PF00029, IPR013092, SM00037): Connexin SieB (PF14163, IPR025982): Super-infection exclusion protein B |
38 |
GRB2 | oncoprotein | 56 | 0.199 | 806.034 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093) |
39 |
GTSE1 | interactor | 26 | 0.615 | 33.275 | GTSE1_N (PF15259, IPR032768): G-2 and S-phase expressed 1 |
40 |
HGS | interactor | 18 | 0.333 | 70.538 | FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif VHS (PF00790, IPR002014, SM00288): VHS domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate PIEZO (PF15917, IPR031805): Piezo |
41 |
HIST4H4 | interactor | 3 | 1.000 | 0 | CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold |
42 |
HSPA1B | interactor | 9 | 0.722 | 1.519 | HSP70 (PF00012, IPR013126): Hsp70 protein |
43 |
HSPA1L | interactor | 10 | 0.400 | 13.497 | HSP70 (PF00012, IPR013126): Hsp70 protein |
44 |
HSPA5 | oncoprotein | 19 | 0.405 | 46.955 | HSP70 (PF00012, IPR013126): Hsp70 protein |
45 |
HSPA8 | oncoprotein | 20 | 0.479 | 40.369 | HSP70 (PF00012, IPR013126): Hsp70 protein |
46 |
HSPA9 | oncoprotein | 13 | 0.551 | 10.663 | HSP70 (PF00012, IPR013126): Hsp70 protein |
47 |
IQGAP1 | interactor | 26 | 0.606 | 35.525 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF87 (PF01935, IPR002789): Domain of unknown function DUF87 IDEAL (PF08858, IPR014957, SM00914): IDEAL domain IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase RasGAP_C (PF03836, IPR000593): RasGAP C-terminus WW (PF00397, IPR001202, SM00456): WW domain |
48 |
ITGA4 | interactor | 33 | 0.339 | 129.691 | FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha |
49 |
ITSN1 | interactor | 14 | 0.333 | 37.439 | C2 (PF00168, IPR000008, SM00239): C2 domain VIT1 (PF01988, IPR008217): VIT family DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) FmdE (PF02663, IPR003814): FmdE, Molybdenum formylmethanofuran dehydrogenase operon GSH_synthase (PF03199, IPR004887): Eukaryotic glutathione synthase RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) SH3_9 (PF14604, IPR001452): Variant SH3 domain DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748) INTAP (PF16617): Intersectin and clathrin adaptor AP2 binding region PH_13 (PF16652, IPR001849): Pleckstrin homology domain |
50 |
ITSN2 | protein found in more fusions | 6 | 0.800 | 0.556 | C2 (PF00168, IPR000008, SM00239): C2 domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) SH3_9 (PF14604, IPR001452): Variant SH3 domain MRP-S26 (PF14943, IPR026140): Mitochondrial ribosome subunit S26 VIR_N (PF15912, IPR031801): Virilizer, N-terminal PH_13 (PF16652, IPR001849): Pleckstrin homology domain |
51 |
KRT1 | interactor | 11 | 0.818 | 2.178 | Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region Keratin_2_head (PF16208, IPR032444): Keratin type II head Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail |
52 |
KRT10 | interactor | 12 | 0.742 | 4.720 | Filament (PF00038, IPR001664): Intermediate filament protein FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
53 |
KRT14 | interactor | 7 | 0.810 | 1.621 | Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region Keratin_2_head (PF16208, IPR032444): Keratin type II head |
54 |
KRT16 | interactor | 9 | 0.750 | 4.506 | Filament (PF00038, IPR001664): Intermediate filament protein zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein Keratin_2_head (PF16208, IPR032444): Keratin type II head |
55 |
KRT17 | interactor | 5 | 1.000 | 0 | DUF1798 (PF08807, IPR014913): Bacterial domain of unknown function (DUF1798) Filament (PF00038, IPR001664): Intermediate filament protein |
56 |
KRT2 | interactor | 10 | 0.756 | 4.632 | Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head |
57 |
KRT3 | interactor | 5 | 1.000 | 0 | Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head |
58 |
KRT32 | interactor | 2 | 1.000 | 0 | Filament (PF00038, IPR001664): Intermediate filament protein Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein |
59 |
KRT33B | interactor | 4 | 0.667 | 1.000 | Filament (PF00038, IPR001664): Intermediate filament protein |
60 |
KRT34 | interactor | 2 | 1.000 | 0 | Filament (PF00038, IPR001664): Intermediate filament protein Peroxin-22 (PF12827, IPR024359): Peroxisomal biogenesis protein family |
61 |
KRT35 | interactor | 2 | 1.000 | 0 | Filament (PF00038, IPR001664): Intermediate filament protein |
62 |
KRT36 | interactor | 3 | 1.000 | 0 | Filament (PF00038, IPR001664): Intermediate filament protein |
63 |
KRT37 | interactor | 1 | 0 | 0 | Filament (PF00038, IPR001664): Intermediate filament protein |
64 |
KRT38 | interactor | 8 | 0.321 | 11.633 | Filament (PF00038, IPR001664): Intermediate filament protein |
65 |
KRT4 | interactor | 5 | 0.600 | 1.786 | Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head |
66 |
KRT5 | interactor | 12 | 0.652 | 11.717 | Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head |
67 |
KRT6A | interactor | 8 | 0.607 | 5.152 | Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head |
68 |
KRT73 | oncoprotein | 4 | 1.000 | 0 | Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head |
69 |
KRT75 | interactor | 1 | 0 | 0 | Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head |
70 |
KRT79 | interactor | 5 | 0.500 | 2.567 | Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head |
71 |
KRT82 | interactor | 3 | 1.000 | 0 | Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head |
72 |
KRT83 | interactor | 3 | 0.667 | 0.286 | Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head |
73 |
KRT85 | interactor | 3 | 1.000 | 0 | Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head |
74 |
KRT86 | interactor | 3 | 1.000 | 0 | Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head |
75 |
KRT9 | interactor | 8 | 0.857 | 0.405 | Filament (PF00038, IPR001664): Intermediate filament protein FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
76 |
KRTAP9-3 | interactor | 1 | 0 | 0 | Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein |
77 |
LAPTM5 | oncoprotein | 5 | 0.700 | 1.452 | Mtp (PF03821, IPR004687): Golgi 4-transmembrane spanning transporter |
78 |
LIMA1 | suppressor | 28 | 0.635 | 31.552 | LIM (PF00412, IPR001781, SM00132): LIM domain ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain |
79 |
MAP4 | oncoprotein | 6 | 0.800 | 0.299 | SdiA-regulated (PF06977, IPR009722): SdiA-regulated Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat DUF3275 (PF11679, IPR021693): Protein of unknown function (DUF3275) |
80 |
MAPK14 | oncoprotein | 8 | 0.429 | 7.134 | Pkinase (PF00069, IPR000719): Protein kinase domain |
81 |
MAPRE1 | oncoprotein | 15 | 0.516 | 15.705 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EB1 (PF03271, IPR004953): EB1-like C-terminal motif SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
82 |
MCCC2 | interactor | 4 | 0.667 | 0.167 | Carboxyl_trans (PF01039, IPR000022): Carboxyl transferase domain |
83 |
MYH9 | oncoprotein | 29 | 0.640 | 33.468 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
84 |
MYO19 | interactor | 22 | 0.784 | 14.484 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
85 |
NAGPA | interactor | 3 | 1.000 | 0 | EGF_2 (PF07974, IPR013111): EGF-like domain NAGPA (PF09992, IPR018711): Phosphodiester glycosidase |
86 |
NECAP1 | interactor | 6 | 0.867 | 0.450 | DUF1681 (PF07933, IPR012466): Protein of unknown function (DUF1681) |
87 |
NECAP2 | interactor | 13 | 0.500 | 16.321 | DUF1681 (PF07933, IPR012466): Protein of unknown function (DUF1681) |
88 |
NEDD4 | suppressor | 16 | 0.333 | 43.919 | Rota_NS26 (PF01525, IPR002512): Rotavirus NS26 WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
89 |
NONO | oncoprotein | 10 | 0.583 | 2.675 | GvpL_GvpF (PF06386, IPR009430): Gas vesicle synthesis protein GvpL/GvpF NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAS_7 (PF12860): PAS fold SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
90 |
NTRK1 | oncoprotein | 45 | 0.241 | 374.599 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
91 |
NUMB | suppressor | 13 | 0.667 | 7.741 | NumbF (PF06311, IPR010449): NUMB domain PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) |
92 |
OCLN | interactor | 4 | 0.833 | 0.250 | MARVEL (PF01284, IPR008253): Membrane-associating domain Occludin_ELL (PF07303, IPR010844): Occludin homology domain EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal |
93 |
OPTN | protein found in more fusions | 5 | 0.833 | 0.333 | ARD (PF03079, IPR004313): ARD/ARD' family bZIP_1 (PF00170, IPR004827): bZIP transcription factor HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator |
94 |
PARK2 | suppressor | 24 | 0.229 | 131.856 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
95 |
PCCB | interactor | 2 | 1.000 | 0 | Carboxyl_trans (PF01039, IPR000022): Carboxyl transferase domain |
96 |
PDLIM7 | interactor | 14 | 0.670 | 14.047 | LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749) |
97 |
PICALM | oncoprotein | 27 | 0.590 | 39.931 | ANTH (PF07651, IPR011417): ANTH domain |
98 |
PPP1CB | interactor | 21 | 0.595 | 31.533 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
99 |
PRDX1 | oncoprotein | 11 | 0.400 | 10.876 | AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin |
100 |
RAB11FIP2 | protein found in more fusions | 4 | 0.667 | 0.286 | C2 (PF00168, IPR000008, SM00239): C2 domain RBD-FIP (PF09457, IPR019018): FIP domain |
101 |
RABL6 | oncoprotein | 4 | 0.667 | 0.571 | eIF3_subunit (PF08597, IPR013906): Translation initiation factor eIF3 subunit Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain Ras (PF00071, IPR001806, SM00173): Ras family |
102 |
RAD23A | oncoprotein | 9 | 0.571 | 5.078 | UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
103 |
REPS2 | oncoprotein | 4 | 0.833 | 0.154 | DUF737 (PF05300, IPR007964): Protein of unknown function (DUF737) Herpes_DNAp_acc (PF04929, IPR007013): Herpes DNA replication accessory factor K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion |
104 |
RNF11 | protein found in more fusions | 18 | 0.346 | 56.424 | zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-ANAPC11 (PF12861, IPR024991): Anaphase-promoting complex subunit 11 RING-H2 finger |
105 |
SCAMP1 | interactor | 5 | 0.500 | 2.500 | SCAMP (PF04144, IPR007273): SCAMP family DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) |
106 |
SH3BP4 | protein found in more fusions | 5 | 0.500 | 1.952 | SH3_2 (PF07653, IPR011511): Variant SH3 domain ZU5 (PF00791, IPR000906, SM00218): ZU5 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain |
107 |
SLC25A41 | interactor | 9 | 0.583 | 3.750 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
108 |
SLC6A3 | oncoprotein | 4 | 0.500 | 1.036 | SNF (PF00209, IPR000175): Sodium:neurotransmitter symporter family |
109 |
SNAP91 | interactor | 3 | 1.000 | 0 | ANTH (PF07651, IPR011417): ANTH domain MGC-24 (PF05283, IPR007947): Multi-glycosylated core protein 24 (MGC-24), sialomucin Mucin (PF01456, IPR000458): Mucin-like glycoprotein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein DUF3275 (PF11679, IPR021693): Protein of unknown function (DUF3275) |
110 |
SPC25 | interactor | 3 | 0.667 | 0.143 | Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Spindle_Spc25 (PF08234, IPR013255): Chromosome segregation protein Spc25 |
111 |
SPG20 | interactor | 5 | 0.500 | 1.120 | MIT (PF04212, IPR007330, SM00745): MIT (microtubule interacting and transport) domain Senescence (PF06911, IPR009686): Senescence-associated protein |
112 |
STAM2 | interactor | 13 | 0.410 | 28.403 | GAT (PF03127, IPR004152): GAT domain UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif VHS (PF00790, IPR002014, SM00288): VHS domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
113 |
STON2 | interactor | 22 | 0.593 | 24.008 | Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family Stonin2_N (PF12016, IPR022699): Stonin 2 |
114 |
SYNPO | interactor | 22 | 0.701 | 18.189 | Calsarcin (PF05556, IPR008438): Calcineurin-binding protein (Calsarcin) |
115 |
TFAP2A | oncoprotein | 6 | 0.400 | 5.841 | TF_AP-2 (PF03299, IPR013854): Transcription factor AP-2 CYYR1 (PF10873, IPR022640): Cysteine and tyrosine-rich protein 1 Peptidase_Prp (PF04327): Cysteine protease Prp |
116 |
TGFB1 | interactor | 1 | 0 | 0 | TGFb_propeptide (PF00688, IPR001111): TGF-beta propeptide TGF_beta (PF00019, IPR001839, SM00204): Transforming growth factor beta like domain |
117 |
TMEM17 | interactor | 12 | 0.258 | 29.410 | Transmemb_17 (PF09799, IPR019184): Predicted membrane protein DUF3043 (PF11241, IPR021403): Protein of unknown function (DUF3043) |
118 |
TRAF2 | interactor | 13 | 0.318 | 24.346 | MATH (PF00917, IPR002083, SM00061): MATH domain Sina (PF03145, IPR018121): Seven in absentia protein family SlyX (PF04102, IPR007236): SlyX zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger) |
119 |
TUBB | interactor | 16 | 0.517 | 20.817 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
120 |
UBC | protein found in more fusions | 35 | 0.271 | 235.682 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
121 |
UBE2D1 | interactor | 9 | 0.714 | 3.336 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
122 |
UBE2D2 | oncoprotein | 10 | 0.611 | 6.252 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
123 |
UBE2D3 | interactor | 9 | 0.500 | 6.833 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
124 |
UBE2E1 | protein found in more fusions | 6 | 0.500 | 1.983 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein |
125 |
UBE2H | protein found in more fusions | 5 | 0.500 | 1.500 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme Uteroglobin (PF01099, IPR016126, SM00096): Uteroglobin family |
126 |
UBQLN1 | protein found in more fusions | 12 | 0.455 | 14.260 | Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B FAM199X (PF15814, IPR029672): Protein family FAM199X |
127 |
UBQLN2 | protein found in more fusions | 9 | 0.607 | 4.755 | Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family SUZ (PF12752, IPR024771): SUZ domain Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B |
128 |
USP8 | interactor | 10 | 0.500 | 12.586 | DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) USP8_dimer (PF08969, IPR015063): USP8 dimerisation domain SET (PF00856, IPR001214, SM00317): SET domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain NAM-associated (PF14303, IPR029466): No apical meristem-associated C-terminal domain |
129 |
VCAM1 | interactor | 32 | 0.317 | 114.121 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
130 |
VSIG8 | interactor | 1 | 0 | 0 | V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
131 |
XPO1 | interactor | 31 | 0.316 | 166.140 | CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region |