1 |
EPAS1 | parental protein | 102 | 0.100 | 6894.127 | Corona_I (PF03187, IPR004876): Corona nucleocapsid I protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 PAS_11 (PF14598): PAS domain |
2 |
AKAP8L | interactor | 3 | 0.667 | 0.500 | AKAP95 (PF04988, IPR007071): A-kinase anchoring protein 95 (AKAP95) DUF3464 (PF11947, IPR021855): Protein of unknown function (DUF3464) |
3 |
APC | suppressor | 8 | 0.476 | 5.836 | APC_15aa (PF05972, IPR009240): APC 15 residue motif APC_basic (PF05956, IPR009234): APC basic domain APC_r (PF05923): APC repeat Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) EB1_binding (PF05937, IPR009232): EB-1 Binding Domain FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) SAMP (PF05924, IPR009224): SAMP Motif Suppressor_APC (PF11414, IPR026831): Adenomatous polyposis coli tumour suppressor protein AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term SAS4 (PF15460, IPR029184): Something about silencing, SAS, complex subunit 4 Arm_APC_u3 (PF16629): Armadillo-associated region on APC APC_u5 (PF16630): Unstructured region on APC between 1st and 2nd catenin-bdg motifs APC_u9 (PF16633): Unstructured region on APC between 1st two creatine-rich regions APC_u13 (PF16634): Unstructured region on APC between APC_crr and SAMP APC_u14 (PF16635): Unstructured region on APC between SAMP and APC_crr APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6 APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain |
4 |
ARID1B | oncoprotein | 8 | 1.000 | 0 | ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin (PF01080, IPR001108): Presenilin DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) DUF2235 (PF09994, IPR018712): Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) BAF250_C (PF12031, IPR021906): SWI/SNF-like complex subunit BAF250/Osa Spt20 (PF12090, IPR021950): Spt20 family |
5 |
ARNT | oncoprotein | 6 | 0.600 | 2.404 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_11 (PF14598): PAS domain PRAS (PF15798, IPR026682): Proline-rich AKT1 substrate 1 |
6 |
ARNT2 | interactor | 3 | 0.667 | 1.000 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold PAP2 (PF01569, IPR000326, SM00014): PAP2 superfamily |
7 |
ARNTL | suppressor | 6 | 0.733 | 1.136 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_11 (PF14598): PAS domain |
8 |
BAG2 | protein found in more fusions | 7 | 0.800 | 0.821 | IncA (PF04156, IPR007285): IncA protein Mnd1 (PF03962, IPR005647): Mnd1 family ParD_antitoxin (PF03693, IPR022789): Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH |
9 |
BATF | oncoprotein | 7 | 0.667 | 3.567 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
10 |
BATF2 | suppressor | 4 | 0.833 | 0.400 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
11 |
BATF3 | protein found in more fusions | 6 | 0.900 | 0.400 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
12 |
BBS1 | interactor | 1 | 0 | 0 | BBS1 (PF14779, IPR032728): Ciliary BBSome complex subunit 1 BBS2_Mid (PF14783, IPR029429): Ciliary BBSome complex subunit 2, middle region |
13 |
BBS2 | interactor | 1 | 0 | 0 | BBS2_N (PF14781, IPR029430): Ciliary BBSome complex subunit 2, N-terminal BBS2_C (PF14782, IPR029333): Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid (PF14783, IPR029429): Ciliary BBSome complex subunit 2, middle region |
14 |
BBS4 | interactor | 1 | 0 | 0 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat Mu-like_Pro (PF10123, IPR012106): Mu-like prophage I protein TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
15 |
BCL7C | suppressor | 8 | 1.000 | 0 | BCL_N (PF04714, IPR006804): BCL7, N-terminal conserver region |
16 |
CNOT1 | interactor | 5 | 0.700 | 1.400 | Not1 (PF04054, IPR007196): CCR4-Not complex component, Not1 DUF3439 (PF11921, IPR024592): Domain of unknown function (DUF3439) DUF3819 (PF12842, IPR024557): Domain of unknown function (DUF3819) EF-hand_8 (PF13833, IPR002048): EF-hand domain pair CNOT1_CAF1_bind (PF16415, IPR032191): CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind (PF16417, IPR032193): CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT (PF16418, IPR032194): CCR4-NOT transcription complex subunit 1 HEAT repeat |
17 |
CNOT10 | interactor | 5 | 0.600 | 2.833 | DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) POX (PF07526, IPR006563, SM00574): Associated with HOX Secretin_N_2 (PF07655, IPR011514): Secretin N-terminal domain TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 (PF13428): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat SRP_TPR_like (PF17004, IPR031545): Putative TPR-like repeat |
18 |
CNOT7 | interactor | 5 | 0.700 | 1.667 | CAF1 (PF04857, IPR006941): CAF1 family ribonuclease |
19 |
CREBBP | suppressor | 19 | 0.392 | 50.514 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) |
20 |
CTNNB1 | oncoprotein | 15 | 0.390 | 34.731 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat |
21 |
DBP | interactor | 5 | 0.800 | 1.000 | bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper |
22 |
DCAF7 | interactor | 4 | 0.500 | 0.900 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
23 |
DDIT3 | oncoprotein | 9 | 0.607 | 7.233 | IFP_35_N (PF07334, IPR009938): Interferon-induced 35 kDa protein (IFP 35) N-terminus bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper |
24 |
DNAJA2 | interactor | 9 | 0.556 | 5.404 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain |
25 |
DPF2 | interactor | 8 | 1.000 | 0 | PHD (PF00628, IPR019787, SM00249): PHD-finger zf-C2H2_4 (PF13894): C2H2-type zinc finger Requiem_N (PF14051, IPR025750): N-terminal domain of DPF2/REQ. PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal Zf_RING (PF16744, IPR031946): KIAA1045 RING finger |
26 |
DPY30 | interactor | 3 | 1.000 | 0 | Dpy-30 (PF05186, IPR007858): Dpy-30 motif |
27 |
EGLN1 | suppressor | 5 | 0.833 | 0.667 | zf-MYND (PF01753, IPR002893): MYND finger 2OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily |
28 |
EGLN2 | interactor | 4 | 1.000 | 0 | 2OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily |
29 |
EGLN3 | suppressor | 6 | 0.700 | 2.000 | 2OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily |
30 |
ELAVL1 | oncoprotein | 23 | 0.221 | 125.933 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
31 |
EMD | interactor | 11 | 0.333 | 22.050 | LEM (PF03020, IPR003887, SM00540): LEM domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein |
32 |
EP300 | oncoprotein | 27 | 0.249 | 155.932 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type |
33 |
ETS1 | oncoprotein | 8 | 0.750 | 1.898 | Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain |
34 |
EWSR1 | oncoprotein | 19 | 0.320 | 70.825 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
35 |
F12 | interactor | 3 | 1.000 | 0 | EGF (PF00008, IPR000742, SM00181): EGF-like domain fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain Kringle (PF00051, IPR000001): Kringle domain Trypsin (PF00089, IPR001254, SM00020): Trypsin |
36 |
GTF3C3 | interactor | 6 | 0.467 | 2.838 | BUD22 (PF09073, IPR015158): BUD22 PGA2 (PF07543, IPR011431): Protein trafficking PGA2 TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat Foie-gras_1 (PF11817, IPR021773): Foie gras liver health family 1 DUF3369 (PF11849, IPR021800): Domain of unknown function (DUF3369) ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat TPR_20 (PF14561): Tetratricopeptide repeat |
37 |
HIF1A | suppressor | 32 | 0.204 | 314.361 | Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 |
38 |
HSP90AA1 | oncoprotein | 18 | 0.368 | 47.060 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
39 |
HSPA4 | interactor | 12 | 0.515 | 16.765 | Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5 |
40 |
IKBKAP | interactor | 2 | 0 | 0 | IKI3 (PF04762, IPR006849): IKI3 family Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS MMU163 (PF17119, IPR031342): Mitochondrial protein up-regulated during meiosis |
41 |
JUN | oncoprotein | 21 | 0.326 | 81.824 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor |
42 |
KDM1A | protein found in more fusions | 8 | 0.381 | 8.638 | Amino_oxidase (PF01593, IPR002937): Flavin containing amine oxidoreductase CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain SWIRM (PF04433, IPR007526): SWIRM domain DUF4298 (PF14131, IPR025384): Domain of unknown function (DUF4298) |
43 |
KLHL20 | interactor | 5 | 0.667 | 1.500 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif |
44 |
LAMP1 | interactor | 3 | 1.000 | 0 | Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp) |
45 |
MAP1LC3A | interactor | 3 | 1.000 | 0 | Atg8 (PF02991, IPR004241): Autophagy protein Atg8 ubiquitin like |
46 |
MAX | suppressor | 9 | 0.571 | 4.091 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain SlyX (PF04102, IPR007236): SlyX |
47 |
MCM3 | interactor | 6 | 0.533 | 5.200 | MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
48 |
MCM7 | protein found in more fusions | 5 | 0.833 | 0.400 | MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
49 |
MED1 | interactor | 22 | 0.871 | 7.785 | Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 Med1 (PF10744, IPR019680): Mediator of RNA polymerase II transcription subunit 1 DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR |
50 |
MED10 | interactor | 20 | 0.942 | 1.552 | Med10 (PF09748, IPR019145): Transcription factor subunit Med10 of Mediator complex |
51 |
MED11 | interactor | 18 | 0.974 | 0.533 | Med11 (PF10280, IPR019404): Mediator complex protein |
52 |
MED12 | oncoprotein | 22 | 0.797 | 25.285 | Med12 (PF09497, IPR019035): Transcription mediator complex subunit Med12 Peptidase_S15 (PF02129, IPR000383): X-Pro dipeptidyl-peptidase (S15 family) DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 DUF2877 (PF11392, IPR021530): Protein of unknown function (DUF2877) Med12-PQL (PF12144, IPR021989): Eukaryotic Mediator 12 catenin-binding domain Med12-LCEWAV (PF12145, IPR021990): Eukaryotic Mediator 12 subunit domain CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance |
53 |
MED14 | interactor | 20 | 0.889 | 6.603 | Med14 (PF08638, IPR013947): Mediator complex subunit MED14 |
54 |
MED15 | protein found in more fusions | 22 | 0.762 | 23.053 | Med15 (PF09606, IPR019087): ARC105 or Med15 subunit of Mediator complex non-fungal |
55 |
MED16 | interactor | 19 | 0.965 | 0.836 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Med16 (PF11635, IPR021665): Mediator complex subunit 16 |
56 |
MED17 | oncoprotein | 21 | 0.857 | 17.785 | Med17 (PF10156, IPR019313): Subunit 17 of Mediator complex |
57 |
MED18 | interactor | 19 | 0.971 | 0.644 | Med18 (PF09637, IPR019095): Med18 protein |
58 |
MED20 | interactor | 22 | 0.753 | 36.644 | Med20 (PF08612, IPR013921): TATA-binding related factor (TRF) of subunit 20 of Mediator complex |
59 |
MED22 | interactor | 15 | 0.990 | 0.111 | Med22 (PF06179, IPR009332): Surfeit locus protein 5 subunit 22 of Mediator complex |
60 |
MED23 | interactor | 27 | 0.530 | 112.754 | Med23 (PF11573, IPR021629): Mediator complex subunit 23 |
61 |
MED24 | interactor | 21 | 0.862 | 12.635 | Med24_N (PF11277, IPR021429): Mediator complex subunit 24 N-terminal |
62 |
MED25 | interactor | 16 | 0.886 | 6.400 | Med25 (PF11232, IPR021394): Mediator complex subunit 25 PTOV activation and synapsin 2 Med25_SD1 (PF11235, IPR021397): Mediator complex subunit 25 synapsin 1 Med25_NR-box (PF11244, IPR021406): Mediator complex subunit 25 C-terminal NR box-containing Med25_VWA (PF11265, IPR021419): Mediator complex subunit 25 von Willebrand factor type A |
63 |
MED26 | interactor | 21 | 0.871 | 7.935 | Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain Med26_C (PF15693, IPR031416): Mediator complex subunit 26 C-terminal Med26_M (PF15694, IPR031417): Mediator complex subunit 26 middle domain |
64 |
MED27 | interactor | 19 | 0.971 | 0.644 | Med27 (PF11571, IPR021627): Mediator complex subunit 27 |
65 |
MED29 | interactor | 21 | 0.942 | 1.552 | Med29 (PF11568, IPR021018): Mediator complex subunit 29 |
66 |
MED4 | interactor | 27 | 0.556 | 120.002 | Med4 (PF10018, IPR019258): Vitamin-D-receptor interacting Mediator subunit 4 |
67 |
MED7 | interactor | 20 | 0.942 | 1.552 | Med7 (PF05983, IPR009244): MED7 protein DotU (PF09850, IPR017732): Type VI secretion system protein DotU |
68 |
MED8 | interactor | 20 | 0.826 | 22.094 | Med8 (PF10232, IPR019364): Mediator of RNA polymerase II transcription complex subunit 8 |
69 |
MEF2C | oncoprotein | 4 | 0.833 | 0.250 | SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat |
70 |
MITF | oncoprotein | 5 | 0.500 | 2.015 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain DUF3371 (PF11851, IPR021802): Domain of unknown function (DUF3371) DUF4355 (PF14265, IPR025580): Domain of unknown function (DUF4355) Di19_C (PF14571, IPR027935): Stress-induced protein Di19, C-terminal MITF_TFEB_C_3_N (PF15951, IPR031867): MITF/TFEB/TFEC/TFE3 N-terminus |
71 |
NCAPD3 | interactor | 2 | 1.000 | 0 | DUF3013 (PF11217, IPR021380): Protein of unknown function (DUF3013) CLASP_N (PF12348, IPR024395): CLASP N terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Cnd3 (PF12719, IPR025977): Nuclear condensing complex subunits, C-term domain |
72 |
NDN | suppressor | 3 | 1.000 | 0 | MAGE (PF01454, IPR002190): MAGE family |
73 |
NPM1 | suppressor | 17 | 0.367 | 41.060 | Nucleoplasmin (PF03066): Nucleoplasmin SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain |
74 |
PHB | suppressor | 10 | 0.378 | 18.786 | Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family DUF4290 (PF14123, IPR025632): Domain of unknown function (DUF4290) |
75 |
PHB2 | interactor | 5 | 0.500 | 3.500 | DUF2605 (PF10792, IPR019728): Protein of unknown function (DUF2605) Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family |
76 |
PSMB1 | interactor | 6 | 0.667 | 3.500 | Proteasome (PF00227, IPR001353): Proteasome subunit |
77 |
PSMC3 | interactor | 9 | 0.464 | 10.852 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) DUF3713 (PF12506, IPR022186): Protein of unknown function (DUF3713) JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II |
78 |
PSMD1 | interactor | 8 | 0.536 | 7.002 | PA26 (PF04636, IPR006730): PA26 p53-induced protein (sestrin) PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat HEAT_2 (PF13646): HEAT repeats |
79 |
SIN3A | oncoprotein | 13 | 0.526 | 18.417 | Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein |
80 |
SIRT1 | suppressor | 13 | 0.455 | 16.314 | DUF592 (PF04574, IPR007654): Protein of unknown function (DUF592) SIR2 (PF02146, IPR003000): Sir2 family TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain |
81 |
SMAD3 | oncoprotein | 23 | 0.299 | 102.638 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
82 |
SMARCA2 | suppressor | 13 | 0.590 | 15.392 | DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168) DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain YL1 (PF05764, IPR008895): YL1 nuclear protein BRK (PF07533, IPR006576, SM00592): BRK domain DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
83 |
SMARCA4 | suppressor | 19 | 0.398 | 63.330 | DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain BRK (PF07533, IPR006576, SM00592): BRK domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065) SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
84 |
SMARCB1 | suppressor | 14 | 0.564 | 16.116 | SNF5 (PF04855, IPR006939): SNF5 / SMARCB1 / INI1 |
85 |
SMARCC1 | suppressor | 17 | 0.492 | 30.190 | SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF2618 (PF10940, IPR021237): Protein of unknown function (DUF2618) PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal |
86 |
SMARCC2 | interactor | 17 | 0.441 | 42.757 | GHMP_kinases_N (PF00288, IPR006204): GHMP kinases N terminal domain SWIRM (PF04433, IPR007526): SWIRM domain DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal |
87 |
SOX10 | oncoprotein | 1 | 0 | 0 | Beta-lactamase (PF00144, IPR001466): Beta-lactamase HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box Sox_N (PF12444, IPR022151): Sox developmental protein N terminal |
88 |
SP1 | protein found in more fusions | 19 | 0.438 | 40.134 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
89 |
SPP1 | oncoprotein | 1 | 0 | 0 | Osteopontin (PF00865, IPR002038, SM00017): Osteopontin |
90 |
SQSTM1 | oncoprotein | 14 | 0.321 | 36.831 | PB1 (PF00564, IPR000270, SM00666): PB1 domain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type UBA_5 (PF16577, IPR015940): UBA domain |
91 |
SSBP3 | oncoprotein | 4 | 0.667 | 2.000 | SSDP (PF04503): Single-stranded DNA binding protein, SSDP |
92 |
STAT5A | suppressor | 5 | 0.500 | 0.819 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain |
93 |
STUB1 | suppressor | 12 | 0.509 | 14.429 | U-box (PF04564, IPR003613, SM00504): U-box domain ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_20 (PF14561): Tetratricopeptide repeat |
94 |
TCEB2 | interactor | 5 | 0.600 | 2.667 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
95 |
TERF2IP | protein found in more fusions | 5 | 0.500 | 1.400 | BRF1 (PF07741, IPR011665): Brf1-like TBP-binding domain Histone_HNS (PF00816, IPR001801): H-NS histone family Myb_DNA-bind_2 (PF08914, IPR015010): Rap1 Myb domain Rap1_C (PF11626, IPR021661): TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391) BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain |
96 |
TFAP2A | suppressor | 10 | 0.511 | 8.437 | TF_AP-2 (PF03299, IPR013854): Transcription factor AP-2 CYYR1 (PF10873, IPR022640): Cysteine and tyrosine-rich protein 1 Peptidase_Prp (PF04327): Cysteine protease Prp |
97 |
TRIM33 | oncoprotein | 10 | 0.472 | 12.083 | PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Siva (PF05458, IPR022773): Cd27 binding protein (Siva) Spectrin (PF00435, IPR002017): Spectrin repeat TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Bromodomain (PF00439, IPR001487, SM00297): Bromodomain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger |
98 |
UBC | protein found in more fusions | 18 | 0.265 | 70.657 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
99 |
VHL | suppressor | 17 | 0.350 | 49.192 | Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein VHL_C (PF17211): VHL box domain |
100 |
WRNIP1 | interactor | 4 | 0.667 | 0.286 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein RuvB_N (PF05496, IPR008824): Holliday junction DNA helicase ruvB N-terminus Sgf11 (PF08209, IPR013246): Sgf11 (transcriptional regulation protein) MgsA_C (PF12002, IPR021886): MgsA AAA+ ATPase C terminal AAA_assoc_2 (PF16193, IPR032423): AAA C-terminal domain |
101 |
XPO1 | interactor | 23 | 0.154 | 172.219 | CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region |
102 |
YTHDF2 | interactor | 4 | 0.667 | 0.472 | YTH (PF04146, IPR007275): YT521-B-like domain DUF4106 (PF13388, IPR025179): Protein of unknown function (DUF4106) |