Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins ELF1, CCT2 (from a repository: Sat Jan 18 09:13:33 2020)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
Layout Tree Circle Radial Force Directed Preset
Export graph PNG file PDF file SVG file SIF file XML file GraphML file

Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 191 The number (and %) of the onco-proteins 53 (27.75 %) The number (and %) of the tumor suppressors 26 (13.61 %) Total number of binary PPIs (saturation %) 2377 (13.10 %) The number (and %) of affected PPIs 189 (7.95 %) The number of possible different fusions 36 PPI diameter 5 PPI radius 3 The average degree of PPI 24.105 Assortativity coefficient -0.2933 The network average Clustering coefficient 0.563 The number (and %) of a zero Clustering coefficients 2 (1.05 %) The number (and %) of a zero Betweenness Centrality 16 (8.38 %)

ACTIVE INTERACTORS MISSING INTERACTORS (in fusions)

List of the fusions
PPI for parental proteins: ELF1,CCT2	All fusions : BG180662;
Proteins found in more fusions	U2AF2 (see 2 fusions); NPM1 (see 1 fusions); CUL1 (see 3 fusions); GRB2 (see 1 fusions); LGALS3BP (see 2 fusions); VHL (see 1 fusions); GAN (see 1 fusions); HDAC5 (see 1 fusions); SNW1 (see 1 fusions); VCP (see 4 fusions); HSP90AA1 (see 2 fusions); HUWE1 (see 2 fusions); HSP90AB1 (see 1 fusions); EEF1D (see 3 fusions); TCF3 (see 4 fusions); SHC1 (see 1 fusions); TUBG1 (see 1 fusions); PSMC2 (see 1 fusions); STAU1 (see 2 fusions); CUL7 (see 2 fusions); CUL3 (see 1 fusions); MYC (see 1 fusions); RUNX1 (see 1 fusions); ACTB (see 3 fusions); COPS5 (see 1 fusions); PEX14 (see 1 fusions); UBC (see 1 fusions); PRPF40A (see 2 fusions); TP53 (see 3 fusions); ILK (see 1 fusions); CRY2 (see 3 fusions); TRIM28 (see 1 fusions); NFKB1 (see 2 fusions); SP1 (see 1 fusions); MCM2 (see 1 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	ELF1	parental protein	7	0.333	388.196	Ets (PF00178, IPR000418, SM00413): Ets-domain PAPA-1 (PF04795, IPR006880): PAPA-1-like conserved region Elf-1_N (PF12310, IPR022084): Transcription factor protein N terminal
2	CCT2	parental protein	182	0.125	10829.103	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
3	ACTA1	interactor	13	0.462	8.005	Actin (PF00022, IPR004000, SM00268): Actin
4	ACTB	oncoprotein	36	0.343	91.992	Actin (PF00022, IPR004000, SM00268): Actin
5	ACTL6A	interactor	16	0.683	5.539	Actin (PF00022, IPR004000, SM00268): Actin
6	ACTR1B	interactor	8	0.929	0.314	Actin (PF00022, IPR004000, SM00268): Actin
7	ACTR2	interactor	22	0.623	14.631	Actin (PF00022, IPR004000, SM00268): Actin
8	AHSA1	interactor	21	0.533	20.148	Aha1_N (PF09229, IPR015310, SM01000): Activator of Hsp90 ATPase, N-terminal AHSA1 (PF08327, IPR013538): Activator of Hsp90 ATPase homolog 1-like protein
9	ALKBH3	interactor	9	0.556	2.809	2OG-FeII_Oxy_2 (PF13532, IPR027450): 2OG-Fe(II) oxygenase superfamily
10	AMBRA1	interactor	16	0.575	10.571	Acyl_CoA_thio (PF02551, IPR025652): Acyl-CoA thioesterase eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Spt20 (PF12090, IPR021950): Spt20 family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
11	ARMC6	interactor	12	0.667	6.497	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Mis14 (PF08641, IPR013950): Kinetochore protein Mis14 like Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
12	ATF2	oncoprotein	17	0.367	68.628	bZIP_1 (PF00170, IPR004827): bZIP transcription factor zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
13	ATG16L1	interactor	8	0.667	1.072	ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2332 (PF10094, IPR011200): Uncharacterized protein conserved in bacteria (DUF2332) Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
14	ATP6V1B1	interactor	2	1.000	0	ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain DUF3533 (PF12051, IPR022703): Protein of unknown function (DUF3533)
15	B9D1	interactor	9	0.972	0.250	Ribosomal_L40e (PF01020, IPR001975): Ribosomal L40e family
16	BTRC	oncoprotein	31	0.331	221.333	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like
17	BUB1B	oncoprotein	12	0.436	7.547	Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1 Mad3_BUB1_II (PF08171, IPR012572): Mad3/BUB1 homology region 2 Pkinase (PF00069, IPR000719): Protein kinase domain XhlA (PF10779, IPR019715): Haemolysin XhlA CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
18	BUB3	interactor	17	0.596	8.899	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
19	C11orf54	interactor	2	1.000	0	DUF1907 (PF08925, IPR015021, SM01168): Domain of Unknown Function (DUF1907)
20	CAMKMT	interactor	8	0.571	1.391	Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase
21	CASP7	interactor	6	0.300	8.809	Peptidase_C14 (PF00656, IPR011600): Caspase domain PRIMA1 (PF16101): Proline-rich membrane anchor 1
22	CCDC8	interactor	29	0.532	26.765	Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA
23	CCNE1	oncoprotein	9	0.417	4.695	Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
24	CCT3	interactor	119	0.170	1959.515	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
25	CCT4	interactor	112	0.175	1668.347	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
26	CCT5	interactor	97	0.207	1066.914	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
27	CCT6A	interactor	113	0.176	1738.100	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
28	CCT6B	interactor	37	0.300	203.522	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
29	CCT7	interactor	107	0.177	1627.768	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
30	CCT8	interactor	100	0.215	1042.900	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
31	CDC20	oncoprotein	27	0.526	33.924	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
32	CDC5L	interactor	46	0.431	130.604	OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
33	CDK15	interactor	6	0.667	0.959	Pkinase (PF00069, IPR000719): Protein kinase domain ACT_5 (PF13710): ACT domain
34	CDK2	suppressor	52	0.322	476.846	Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain
35	CDK5	oncoprotein	15	0.659	4.798	Pkinase (PF00069, IPR000719): Protein kinase domain
36	CDK7	oncoprotein	8	0.762	1.297	Pkinase (PF00069, IPR000719): Protein kinase domain
37	CETN2	interactor	7	1.000	0	EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
38	COPS5	protein found in more fusions	45	0.379	184.514	JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
39	CRY2	protein found in more fusions	20	0.503	16.807	DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
40	CTTNBP2	interactor	14	0.769	8.195	Carmo_coat_C (PF08462, IPR013669): Carmovirus coat protein CortBP2 (PF09727, IPR019131): Cortactin-binding protein-2 Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour
41	CUL1	suppressor	47	0.384	153.987	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
42	CUL3	protein found in more fusions	68	0.290	626.377	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
43	CUL7	protein found in more fusions	40	0.417	126.510	ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
44	CYB5B	interactor	2	1.000	0	Cyt-b5 (PF00173, IPR001199, SM01117): Cytochrome b5-like Heme/Steroid binding domain MIP (PF00230, IPR000425): Major intrinsic protein
45	DCAF5	interactor	7	0.905	0.187	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2634 (PF10934, IPR020288): Protein of unknown function (DUF2634) IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
46	DCAF7	interactor	11	0.891	1.186	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
47	DDB2	suppressor	14	0.769	4.606	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
48	DNAJA1	interactor	44	0.328	190.525	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
49	DNAJA4	interactor	12	0.636	4.555	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
50	EEF1D	protein found in more fusions	19	0.464	11.107	EF1_GNE (PF00736, IPR014038, SM00888): EF-1 guanine nucleotide exchange domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
51	EEF2	interactor	30	0.372	90.362	EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II
52	ENDOV	interactor	1	0	0	Endonuclease_5 (PF04493, IPR007581): Endonuclease V
53	ERLIN2	interactor	13	0.423	16.175	Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family DUF4346 (PF14251, IPR025595): Domain of unknown function (DUF4346)
54	ESR1	suppressor	35	0.383	147.475	Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
55	FAM86B2	interactor	11	0.818	1.244	Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase FAM86 (PF14904, IPR029426): Family of unknown function
56	FBXO6	interactor	38	0.378	92.649	FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like
57	FBXW4	oncoprotein	11	0.800	1.383	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat F-box-like (PF12937, IPR001810): F-box-like F-box_4 (PF15966, IPR001810): F-box
58	FBXW8	interactor	15	0.629	6.371	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like
59	FCHSD2	interactor	4	1.000	0	Cortex-I_coil (PF09304, IPR015383): Cortexillin I, coiled coil DivIC (PF04977, IPR007060): Septum formation initiator FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain DUF4665 (PF15679, IPR031389): Domain of unknown function (DUF4665) Rit1_C (PF17184): Rit1 N-terminal domain
60	FN1	oncoprotein	38	0.404	125.618	fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
61	FUS	suppressor	39	0.528	62.800	Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Limkain-b1 (PF11608, IPR024582): Limkain b1 FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head
62	FYCO1	interactor	6	1.000	0	Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger HAP1_N (PF04849, IPR006933): HAP1 N-terminal conserved region RUN (PF02759, IPR004012, SM00593): RUN domain Sec8_exocyst (PF04048, IPR007191): Sec8 exocyst complex component specific domain Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Spectrin (PF00435, IPR002017): Spectrin repeat Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal TSC22 (PF01166, IPR000580): TSC-22/dip/bun family bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like GOLD_2 (PF13897, IPR009038): Golgi-dynamics membrane-trafficking DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) DUF4578 (PF15147, IPR028106): Domain of unknown function (DUF4578) HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
63	GAN	protein found in more fusions	20	0.503	17.166	BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif
64	GPR37	interactor	6	0.933	0.065	7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
65	GRB2	oncoprotein	34	0.487	133.988	SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
66	GSPT1	oncoprotein	7	0.429	8.983	GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
67	GSPT2	interactor	2	1.000	0	GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
68	GTF2I	interactor	15	0.505	10.107	GTF2I (PF02946, IPR004212): GTF2I-like repeat
69	HDAC1	suppressor	32	0.370	288.201	FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
70	HDAC3	suppressor	20	0.520	120.996	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
71	HDAC5	protein found in more fusions	35	0.456	87.764	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
72	HMGA1	oncoprotein	13	0.372	147.162	AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF2239 (PF09998, IPR018715): Uncharacterized protein conserved in bacteria (DUF2239)
73	HOXC13	oncoprotein	1	0	0	Homeobox (PF00046, IPR001356, SM00389): Homeobox domain HoxA13_N (PF12284, IPR022067): Hox protein A13 N terminal
74	HSP90AA1	oncoprotein	70	0.240	664.940	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
75	HSP90AB1	oncoprotein	56	0.306	330.480	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
76	HSP90B1	suppressor	27	0.436	37.542	CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region
77	HSPA4	interactor	45	0.295	349.355	Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
78	HSPE1	interactor	17	0.537	13.444	Cpn10 (PF00166, IPR020818, SM00883): Chaperonin 10 Kd subunit
79	HSPH1	oncoprotein	20	0.416	34.286	HSP70 (PF00012, IPR013126): Hsp70 protein SICA_alpha (PF12887, IPR024290): SICA extracellular alpha domain
80	HUWE1	oncoprotein	49	0.418	149.272	BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
81	IGBP1	interactor	12	0.955	0.701	TAP42 (PF04177, IPR007304): TAP42-like family
82	IKBKE	interactor	13	0.652	7.120	IncA (PF04156, IPR007285): IncA protein Pkinase (PF00069, IPR000719): Protein kinase domain SlyX (PF04102, IPR007236): SlyX zf-RING_9 (PF13901, IPR025258): Putative zinc-RING and/or ribbon
83	ILK	suppressor	24	0.510	29.782	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies)
84	IQGAP1	interactor	29	0.379	55.120	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF87 (PF01935, IPR002789): Domain of unknown function DUF87 IDEAL (PF08858, IPR014957, SM00914): IDEAL domain IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase RasGAP_C (PF03836, IPR000593): RasGAP C-terminus WW (PF00397, IPR001202, SM00456): WW domain
85	IRAK1	interactor	20	0.602	8.603	Death (PF00531, IPR000488, SM00005): Death domain Pkinase (PF00069, IPR000719): Protein kinase domain
86	ISG15	suppressor	13	0.423	10.978	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
87	ITGA4	interactor	33	0.490	43.892	FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
88	JAK3	oncoprotein	7	1.000	0	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain
89	KIF21A	interactor	12	0.879	0.867	DUF1690 (PF07956, IPR012471): Protein of Unknown function (DUF1690) DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Strep_SA_rep (PF06696, IPR009578): Streptococcal surface antigen repeat TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding TSNAXIP1_N (PF15739, IPR032755): Translin-associated factor X-interacting N-terminus DUF4746 (PF15928, IPR031827): Domain of unknown function (DUF4746) HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
90	KPNA4	interactor	14	0.659	7.922	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat IBB (PF01749, IPR002652): Importin beta binding domain Arm_3 (PF16186, IPR032413): Atypical Arm repeat
91	KRAS	oncoprotein	14	0.333	20.497	Ras (PF00071, IPR001806, SM00173): Ras family
92	LFNG	oncoprotein	3	1.000	0	Fringe (PF02434, IPR003378): Fringe-like
93	LGALS3BP	oncoprotein	30	0.589	22.665	BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain SRCR_2 (PF15494, IPR017448): Scavenger receptor cysteine-rich domain
94	LRRK1	interactor	6	0.800	0.271	Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase Pkinase (PF00069, IPR000719): Protein kinase domain TniB (PF05621, IPR008868): Bacterial TniB protein Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat COR (PF16095, IPR032171): C-terminal of Roc, COR, domain
95	MAPK10	suppressor	7	0.600	1.820	Pkinase (PF00069, IPR000719): Protein kinase domain
96	MAPK8	oncoprotein	16	0.505	55.273	DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530) Pkinase (PF00069, IPR000719): Protein kinase domain
97	MCM2	oncoprotein	50	0.402	181.404	AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
98	MEPCE	interactor	13	0.513	7.108	Bin3 (PF06859, IPR010675): Bicoid-interacting protein 3 (Bin3) Methyltransf_23 (PF13489): Methyltransferase domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 DLEU7 (PF15760, IPR031510): Leukemia-associated protein 7
99	METTL18	interactor	11	0.727	1.960	Methyltransf_23 (PF13489): Methyltransferase domain
100	METTL21B	interactor	16	0.650	7.157	Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase
101	MKS1	interactor	9	0.861	0.783	B9-C2 (PF07162, IPR010796): Ciliary basal body-associated, B9 protein
102	MLST8	interactor	4	0.833	0.477	Hira (PF07569, IPR011494): TUP1-like enhancer of split WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
103	MOB4	interactor	15	0.867	2.819	Mob1_phocein (PF03637, IPR005301): Mob1/phocein family
104	MYC	oncoprotein	45	0.350	391.024	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region
105	NEDD1	interactor	16	0.642	11.541	NRBF2 (PF08961, IPR015056): Nuclear receptor-binding factor 2, autophagy regulator eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A FliM (PF02154, IPR001689): Flagellar motor switch protein FliM WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Mto2_bdg (PF12808, IPR024545): Micro-tubular organiser Mto1 C-term Mto2-binding region ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
106	NFKB1	suppressor	16	0.333	226.407	Death (PF00531, IPR000488, SM00005): Death domain GHMP_kinases_C (PF08544, IPR013750): GHMP kinases C terminal RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
107	NFYA	interactor	9	0.444	76.688	CBFB_NFYA (PF02045, IPR001289): CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B MSP1_C (PF07462, IPR010901): Merozoite surface protein 1 (MSP1) C-terminus FixG_C (PF11614, IPR032879): IG-like fold at C-terminal of FixG, putative oxidoreductase DUF4237 (PF14021, IPR025331): Protein of unknown function (DUF4237)
108	NIPSNAP1	interactor	15	0.733	3.135	NIPSNAP (PF07978, IPR012577): NIPSNAP
109	NOS2	interactor	23	0.545	12.309	FAD_binding_1 (PF00667, IPR003097): FAD binding domain Flavodoxin_1 (PF00258, IPR008254): Flavodoxin NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain
110	NPM1	suppressor	49	0.395	196.723	Nucleoplasmin (PF03066): Nucleoplasmin/nucleophosmin domain SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
111	NSFL1C	interactor	9	0.528	10.103	SEP (PF08059, IPR012989, SM00553): SEP domain UBX (PF00789, IPR001012, SM00166): UBX domain UBA_4 (PF14555): UBA-like domain
112	NSMAF	interactor	9	0.861	0.395	Beach (PF02138, IPR000409, SM01026): Beige/BEACH domain GRAM (PF02893, IPR004182, SM00568): GRAM domain NABP (PF07990, IPR012940): Nucleic acid binding protein NABP WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain PH_BEACH (PF14844, IPR023362): PH domain associated with Beige/BEACH
113	NTRK1	oncoprotein	68	0.315	468.656	I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
114	NXF1	interactor	37	0.246	289.016	NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat
115	OBSL1	interactor	36	0.432	97.433	BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
116	PACRG	suppressor	15	0.657	7.070	ParcG (PF10274, IPR019399): Parkin co-regulated protein
117	PAN2	interactor	18	0.484	28.349	RNase_T (PF00929, IPR013520): Exonuclease UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase WD40_like (PF17005, IPR031544): WD40-like domain
118	PARK2	suppressor	30	0.384	105.063	IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
119	PCK1	interactor	10	0.489	2.326	PEPCK (PF00821, IPR008209): Phosphoenolpyruvate carboxykinase
120	PDK3	interactor	9	1.000	0	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 (PF10436, IPR018955): Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase
121	PEX14	protein found in more fusions	14	0.564	6.737	HemX (PF04375, IPR007470): HemX, putative uroporphyrinogen-III C-methyltransferase Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
122	PEX7	interactor	9	0.972	0.182	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
123	PLK4	interactor	5	1.000	0	ABC1 (PF03109, IPR004147): ABC1 family Pkinase (PF00069, IPR000719): Protein kinase domain POLO_box (PF00659, IPR000959): POLO box duplicated region DUF4520 (PF15016, IPR027865): Domain of unknown function (DUF4520)
124	POC1A	interactor	10	0.711	5.961	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
125	POC1B	interactor	3	0.667	0.242	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
126	PPP1CC	oncoprotein	18	0.614	10.004	Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
127	PPP2CA	suppressor	39	0.449	106.489	Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
128	PPP2CB	suppressor	25	0.630	27.025	Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
129	PPP2R2A	interactor	19	0.754	6.323	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
130	PPP2R2B	interactor	15	0.848	2.499	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
131	PPP2R2C	suppressor	13	0.833	3.273	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
132	PPP2R2D	interactor	16	0.850	3.397	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
133	PPP4C	interactor	20	0.642	81.337	Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
134	PRKCDBP	suppressor	2	1.000	0	A1_Propeptide (PF07966, IPR012848): A1 Propeptide PTRF_SDPR (PF15237, IPR026752): PTRF/SDPR family
135	PRPF4	interactor	22	0.667	14.940	PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_like (PF17005, IPR031544): WD40-like domain
136	PRPF40A	protein found in more fusions	15	0.593	6.067	FF (PF01846, IPR002713, SM00441): FF domain MCR_alpha (PF02249, IPR009047): Methyl-coenzyme M reductase alpha subunit, C-terminal domain Transformer (PF06495, IPR010519): Fruit fly transformer protein WW (PF00397, IPR001202, SM00456): WW domain YqzE (PF14038, IPR025622): YqzE-like protein SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6 SRRM_C (PF15230, IPR029360): Serine/arginine repetitive matrix protein C-terminus SOBP (PF15279, IPR026092): Sine oculis-binding protein IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
137	PSMA3	interactor	33	0.427	83.256	Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
138	PSMB8	interactor	6	1.000	0	Proteasome (PF00227, IPR001353): Proteasome subunit
139	PSMC2	protein found in more fusions	34	0.430	82.332	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
140	PSMC6	interactor	24	0.415	37.829	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) AAA_2 (PF07724, IPR013093): AAA domain (Cdc48 subfamily) TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain
141	PSMD2	oncoprotein	36	0.243	159.049	PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat THAP (PF05485, IPR006612, SM00980): THAP domain HEAT_2 (PF13646): HEAT repeats
142	PTPA	suppressor	12	0.727	15.123	PTPA (PF03095, IPR004327): Phosphotyrosyl phosphate activator (PTPA) protein
143	RAD21	oncoprotein	17	0.515	13.319	Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
144	REL	oncoprotein	10	0.244	104.871	RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
145	RFWD2	suppressor	14	0.821	1.553	Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein IncA (PF04156, IPR007285): IncA protein WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) WD40_like (PF17005, IPR031544): WD40-like domain
146	RFWD3	interactor	12	0.682	1.988	OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
147	RPS3	interactor	40	0.324	132.219	KH_2 (PF07650, IPR004044): KH domain Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain
148	RPS6KB2	interactor	26	0.397	37.274	Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
149	RUNX1	suppressor	6	0.200	42.406	Runt (PF00853, IPR013524): Runt domain RunxI (PF08504, IPR013711): Runx inhibition domain DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037)
150	SEC31B	interactor	9	0.917	0.508	SRA1 (PF07304, IPR009917): Steroid receptor RNA activator (SRA1) ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain Sec16_C (PF12931, IPR024298): Sec23-binding domain of Sec16
151	SF3B3	interactor	22	0.489	28.093	CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
152	SHC1	oncoprotein	22	0.414	36.617	PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) SH2 (PF00017, IPR000980, SM00252): SH2 domain
153	SIRT7	interactor	25	0.427	34.515	DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family
154	SMURF1	interactor	21	0.458	15.102	C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
155	SNW1	protein found in more fusions	47	0.375	201.781	SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain
156	SP1	protein found in more fusions	21	0.305	265.195	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
157	SSR1	interactor	11	0.764	1.561	TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
158	SSSCA1	interactor	7	0.533	2.268	Auto_anti-p27 (PF06677, IPR009563): Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27)
159	STAU1	protein found in more fusions	25	0.453	27.495	dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
160	STK24	interactor	19	0.712	14.004	DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241) Pkinase (PF00069, IPR000719): Protein kinase domain
161	STRN	oncoprotein	17	0.853	3.791	CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) Nucleoporin_N (PF08801, IPR014908): Nup133 N terminal like Striatin (PF08232, IPR013258): Striatin family WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
162	STRN3	interactor	17	0.824	5.599	Striatin (PF08232, IPR013258): Striatin family WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
163	TCF3	suppressor	4	0.333	21.639	CDC45 (PF02724, IPR003874): CDC45-like protein HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
164	TCP1	interactor	111	0.191	1645.220	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
165	TP53	suppressor	61	0.319	542.752	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
166	TRIM28	protein found in more fusions	39	0.373	98.338	ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
167	TSSK6	interactor	10	0.733	0.794	Pkinase (PF00069, IPR000719): Protein kinase domain
168	TTLL3	oncoprotein	7	1.000	0	TTL (PF03133, IPR004344): Tubulin-tyrosine ligase family
169	TUBA1B	interactor	21	0.367	47.553	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
170	TUBA1C	interactor	37	0.521	54.287	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
171	TUBA3E	interactor	6	0.867	0.458	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
172	TUBAL3	interactor	8	0.714	1.290	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
173	TUBB	interactor	50	0.309	234.190	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
174	TUBB2A	interactor	20	0.300	36.830	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
175	TUBB2B	interactor	20	0.511	21.153	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
176	TUBG1	protein found in more fusions	31	0.563	35.130	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
177	TXNL1	interactor	9	0.722	1.627	PITH (PF06201, IPR010400): PITH domain Thioredoxin (PF00085, IPR013766): Thioredoxin
178	TYK2	interactor	14	0.654	5.154	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
179	U2AF2	protein found in more fusions	32	0.488	52.432	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein
180	UBC	protein found in more fusions	54	0.331	308.702	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
181	VAV2	oncoprotein	7	0.619	2.337	PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain CotJB (PF12652, IPR024207): CotJB protein
182	VCAM1	interactor	31	0.477	35.937	C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain
183	VCP	protein found in more fusions	64	0.359	450.742	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
184	VHL	suppressor	26	0.557	57.013	Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): VHL beta domain VHL_C (PF17211): VHL box domain
185	VRK2	interactor	6	0.867	0.448	Pkinase (PF00069, IPR000719): Protein kinase domain VP_N-CPKC (PF11475, IPR021573): Virion protein N terminal domain
186	WDR76	interactor	8	0.821	0.228	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat SPATIAL (PF15256): SPATIAL
187	WDR83	interactor	11	0.836	2.345	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
188	WRAP53	oncoprotein	10	0.978	0.222	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
189	WRAP73	interactor	7	0.467	4.227	eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A IKI3 (PF04762, IPR006849): IKI3 family WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2555 (PF10742, IPR019678): Protein of unknown function (DUF2555) ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
190	WWOX	suppressor	14	0.473	12.329	adh_short (PF00106, IPR002198): short chain dehydrogenase WW (PF00397, IPR001202, SM00456): WW domain
191	XIAP	interactor	7	0.400	5.870	BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)

B a c k    t o    T o p ⇑

List of missing interactors (in fusions)

#	Name	Type	Domains (Pfam, InterPro, SMART): description	Fusion(s)
1	ACTA1	interactor	Actin (PF00022, IPR004000, SM00268): Actin	BG180662
2	ACTB	oncoprotein	Actin (PF00022, IPR004000, SM00268): Actin	BG180662
3	ACTL6A	interactor	Actin (PF00022, IPR004000, SM00268): Actin	BG180662
4	ACTR1B	interactor	Actin (PF00022, IPR004000, SM00268): Actin	BG180662
5	ACTR2	interactor	Actin (PF00022, IPR004000, SM00268): Actin	BG180662
6	AHSA1	interactor	Aha1_N (PF09229, IPR015310, SM01000): Activator of Hsp90 ATPase, N-terminal AHSA1 (PF08327, IPR013538): Activator of Hsp90 ATPase homolog 1-like protein	BG180662
7	ALKBH3	interactor	2OG-FeII_Oxy_2 (PF13532, IPR027450): 2OG-Fe(II) oxygenase superfamily	BG180662
8	AMBRA1	interactor	Acyl_CoA_thio (PF02551, IPR025652): Acyl-CoA thioesterase eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Spt20 (PF12090, IPR021950): Spt20 family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
9	ARMC6	interactor	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Mis14 (PF08641, IPR013950): Kinetochore protein Mis14 like Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain	BG180662
10	ATG16L1	interactor	ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2332 (PF10094, IPR011200): Uncharacterized protein conserved in bacteria (DUF2332) Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160	BG180662
11	ATP6V1B1	interactor	ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain DUF3533 (PF12051, IPR022703): Protein of unknown function (DUF3533)	BG180662
12	B9D1	interactor	Ribosomal_L40e (PF01020, IPR001975): Ribosomal L40e family	BG180662
13	BTRC	oncoprotein	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like	BG180662
14	BUB1B	oncoprotein	Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1 Mad3_BUB1_II (PF08171, IPR012572): Mad3/BUB1 homology region 2 Pkinase (PF00069, IPR000719): Protein kinase domain XhlA (PF10779, IPR019715): Haemolysin XhlA CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167	BG180662
15	BUB3	interactor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat	BG180662
16	C11orf54	interactor	DUF1907 (PF08925, IPR015021, SM01168): Domain of Unknown Function (DUF1907)	BG180662
17	CAMKMT	interactor	Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase	BG180662
18	CASP7	interactor	Peptidase_C14 (PF00656, IPR011600): Caspase domain PRIMA1 (PF16101): Proline-rich membrane anchor 1	BG180662
19	CCDC8	interactor	Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA	BG180662
20	CCNE1	oncoprotein	Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain	BG180662
21	CCT2	parental protein	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family	BG180662
22	CCT3	interactor	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family	BG180662
23	CCT4	interactor	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family	BG180662
24	CCT5	interactor	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family	BG180662
25	CCT6A	interactor	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family	BG180662
26	CCT6B	interactor	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family	BG180662
27	CCT7	interactor	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family	BG180662
28	CCT8	interactor	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family	BG180662
29	CDC20	oncoprotein	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
30	CDC5L	interactor	OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain	BG180662
31	CDK15	interactor	Pkinase (PF00069, IPR000719): Protein kinase domain ACT_5 (PF13710): ACT domain	BG180662
32	CDK2	suppressor	Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain	BG180662
33	CDK5	oncoprotein	Pkinase (PF00069, IPR000719): Protein kinase domain	BG180662
34	CDK7	oncoprotein	Pkinase (PF00069, IPR000719): Protein kinase domain	BG180662
35	CETN2	interactor	EF-hand_7 (PF13499, IPR011992): EF-hand domain pair	BG180662
36	COPS5	interactor	JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease	BG180662
37	CRY2	interactor	DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase	BG180662
38	CTTNBP2	interactor	Carmo_coat_C (PF08462, IPR013669): Carmovirus coat protein CortBP2 (PF09727, IPR019131): Cortactin-binding protein-2 Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour	BG180662
39	CUL1	suppressor	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain	BG180662
40	CUL3	interactor	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal	BG180662
41	CUL7	interactor	ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7	BG180662
42	CYB5B	interactor	Cyt-b5 (PF00173, IPR001199, SM01117): Cytochrome b5-like Heme/Steroid binding domain MIP (PF00230, IPR000425): Major intrinsic protein	BG180662
43	DCAF5	interactor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2634 (PF10934, IPR020288): Protein of unknown function (DUF2634) IMUP (PF15761, IPR026621): Immortalisation up-regulated protein	BG180662
44	DCAF7	interactor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat	BG180662
45	DDB2	suppressor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat	BG180662
46	DNAJA1	interactor	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain	BG180662
47	DNAJA4	interactor	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain	BG180662
48	EEF1D	interactor	EF1_GNE (PF00736, IPR014038, SM00888): EF-1 guanine nucleotide exchange domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region	BG180662
49	EEF2	interactor	EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II	BG180662
50	ELF1	parental protein	Ets (PF00178, IPR000418, SM00413): Ets-domain PAPA-1 (PF04795, IPR006880): PAPA-1-like conserved region Elf-1_N (PF12310, IPR022084): Transcription factor protein N terminal	BG180662
51	ENDOV	interactor	Endonuclease_5 (PF04493, IPR007581): Endonuclease V	BG180662
52	ERLIN2	interactor	Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family DUF4346 (PF14251, IPR025595): Domain of unknown function (DUF4346)	BG180662
53	ESR1	suppressor	Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal	BG180662
54	FAM86B2	interactor	Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase FAM86 (PF14904, IPR029426): Family of unknown function	BG180662
55	FBXO6	interactor	FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like	BG180662
56	FBXW4	oncoprotein	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat F-box-like (PF12937, IPR001810): F-box-like F-box_4 (PF15966, IPR001810): F-box	BG180662
57	FBXW8	interactor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like	BG180662
58	FCHSD2	interactor	Cortex-I_coil (PF09304, IPR015383): Cortexillin I, coiled coil DivIC (PF04977, IPR007060): Septum formation initiator FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain DUF4665 (PF15679, IPR031389): Domain of unknown function (DUF4665) Rit1_C (PF17184): Rit1 N-terminal domain	BG180662
59	FN1	oncoprotein	fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)	BG180662
60	FUS	suppressor	Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Limkain-b1 (PF11608, IPR024582): Limkain b1 FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head	BG180662
61	FYCO1	interactor	Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger HAP1_N (PF04849, IPR006933): HAP1 N-terminal conserved region RUN (PF02759, IPR004012, SM00593): RUN domain Sec8_exocyst (PF04048, IPR007191): Sec8 exocyst complex component specific domain Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Spectrin (PF00435, IPR002017): Spectrin repeat Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal TSC22 (PF01166, IPR000580): TSC-22/dip/bun family bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like GOLD_2 (PF13897, IPR009038): Golgi-dynamics membrane-trafficking DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) DUF4578 (PF15147, IPR028106): Domain of unknown function (DUF4578) HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1	BG180662
62	GAN	interactor	BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif	BG180662
63	GPR37	interactor	7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)	BG180662
64	GRB2	oncoprotein	SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)	BG180662
65	GSPT1	oncoprotein	GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region	BG180662
66	GSPT2	interactor	GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region	BG180662
67	GTF2I	interactor	GTF2I (PF02946, IPR004212): GTF2I-like repeat	BG180662
68	HDAC1	suppressor	FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain	BG180662
69	HDAC3	suppressor	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain	BG180662
70	HDAC5	interactor	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4	BG180662
71	HMGA1	oncoprotein	AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF2239 (PF09998, IPR018715): Uncharacterized protein conserved in bacteria (DUF2239)	BG180662
72	HOXC13	oncoprotein	Homeobox (PF00046, IPR001356, SM00389): Homeobox domain HoxA13_N (PF12284, IPR022067): Hox protein A13 N terminal	BG180662
73	HSP90AA1	oncoprotein	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein	BG180662
74	HSP90AB1	oncoprotein	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein	BG180662
75	HSP90B1	suppressor	CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region	BG180662
76	HSPA4	interactor	Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5	BG180662
77	HSPE1	interactor	Cpn10 (PF00166, IPR020818, SM00883): Chaperonin 10 Kd subunit	BG180662
78	HSPH1	oncoprotein	HSP70 (PF00012, IPR013126): Hsp70 protein SICA_alpha (PF12887, IPR024290): SICA extracellular alpha domain	BG180662
79	HUWE1	oncoprotein	BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)	BG180662
80	IGBP1	interactor	TAP42 (PF04177, IPR007304): TAP42-like family	BG180662
81	IKBKE	interactor	IncA (PF04156, IPR007285): IncA protein Pkinase (PF00069, IPR000719): Protein kinase domain SlyX (PF04102, IPR007236): SlyX zf-RING_9 (PF13901, IPR025258): Putative zinc-RING and/or ribbon	BG180662
82	ILK	suppressor	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies)	BG180662
83	IQGAP1	interactor	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF87 (PF01935, IPR002789): Domain of unknown function DUF87 IDEAL (PF08858, IPR014957, SM00914): IDEAL domain IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase RasGAP_C (PF03836, IPR000593): RasGAP C-terminus WW (PF00397, IPR001202, SM00456): WW domain	BG180662
84	IRAK1	interactor	Death (PF00531, IPR000488, SM00005): Death domain Pkinase (PF00069, IPR000719): Protein kinase domain	BG180662
85	ISG15	suppressor	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family	BG180662
86	ITGA4	interactor	FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha	BG180662
87	JAK3	oncoprotein	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain	BG180662
88	KIF21A	interactor	DUF1690 (PF07956, IPR012471): Protein of Unknown function (DUF1690) DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Strep_SA_rep (PF06696, IPR009578): Streptococcal surface antigen repeat TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding TSNAXIP1_N (PF15739, IPR032755): Translin-associated factor X-interacting N-terminus DUF4746 (PF15928, IPR031827): Domain of unknown function (DUF4746) HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1	BG180662
89	KPNA4	interactor	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat IBB (PF01749, IPR002652): Importin beta binding domain Arm_3 (PF16186, IPR032413): Atypical Arm repeat	BG180662
90	KRAS	oncoprotein	Ras (PF00071, IPR001806, SM00173): Ras family	BG180662
91	LFNG	oncoprotein	Fringe (PF02434, IPR003378): Fringe-like	BG180662
92	LGALS3BP	oncoprotein	BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain SRCR_2 (PF15494, IPR017448): Scavenger receptor cysteine-rich domain	BG180662
93	LRRK1	interactor	Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase Pkinase (PF00069, IPR000719): Protein kinase domain TniB (PF05621, IPR008868): Bacterial TniB protein Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat COR (PF16095, IPR032171): C-terminal of Roc, COR, domain	BG180662
94	MAPK10	suppressor	Pkinase (PF00069, IPR000719): Protein kinase domain	BG180662
95	MAPK8	oncoprotein	DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530) Pkinase (PF00069, IPR000719): Protein kinase domain	BG180662
96	MCM2	oncoprotein	AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain	BG180662
97	MEPCE	interactor	Bin3 (PF06859, IPR010675): Bicoid-interacting protein 3 (Bin3) Methyltransf_23 (PF13489): Methyltransferase domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 DLEU7 (PF15760, IPR031510): Leukemia-associated protein 7	BG180662
98	METTL18	interactor	Methyltransf_23 (PF13489): Methyltransferase domain	BG180662
99	METTL21B	interactor	Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase	BG180662
100	MKS1	interactor	B9-C2 (PF07162, IPR010796): Ciliary basal body-associated, B9 protein	BG180662
101	MLST8	interactor	Hira (PF07569, IPR011494): TUP1-like enhancer of split WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160	BG180662
102	MOB4	interactor	Mob1_phocein (PF03637, IPR005301): Mob1/phocein family	BG180662
103	MYC	oncoprotein	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region	BG180662
104	NEDD1	interactor	NRBF2 (PF08961, IPR015056): Nuclear receptor-binding factor 2, autophagy regulator eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A FliM (PF02154, IPR001689): Flagellar motor switch protein FliM WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Mto2_bdg (PF12808, IPR024545): Micro-tubular organiser Mto1 C-term Mto2-binding region ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
105	NIPSNAP1	interactor	NIPSNAP (PF07978, IPR012577): NIPSNAP	BG180662
106	NOS2	interactor	FAD_binding_1 (PF00667, IPR003097): FAD binding domain Flavodoxin_1 (PF00258, IPR008254): Flavodoxin NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain	BG180662
107	NPM1	suppressor	Nucleoplasmin (PF03066): Nucleoplasmin/nucleophosmin domain SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain	BG180662
108	NSFL1C	interactor	SEP (PF08059, IPR012989, SM00553): SEP domain UBX (PF00789, IPR001012, SM00166): UBX domain UBA_4 (PF14555): UBA-like domain	BG180662
109	NSMAF	interactor	Beach (PF02138, IPR000409, SM01026): Beige/BEACH domain GRAM (PF02893, IPR004182, SM00568): GRAM domain NABP (PF07990, IPR012940): Nucleic acid binding protein NABP WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain PH_BEACH (PF14844, IPR023362): PH domain associated with Beige/BEACH	BG180662
110	NTRK1	oncoprotein	I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain	BG180662
111	NXF1	interactor	NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat	BG180662
112	OBSL1	interactor	BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain	BG180662
113	PACRG	suppressor	ParcG (PF10274, IPR019399): Parkin co-regulated protein	BG180662
114	PAN2	interactor	RNase_T (PF00929, IPR013520): Exonuclease UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase WD40_like (PF17005, IPR031544): WD40-like domain	BG180662
115	PARK2	suppressor	IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family	BG180662
116	PCK1	interactor	PEPCK (PF00821, IPR008209): Phosphoenolpyruvate carboxykinase	BG180662
117	PDK3	interactor	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 (PF10436, IPR018955): Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase	BG180662
118	PEX14	interactor	HemX (PF04375, IPR007470): HemX, putative uroporphyrinogen-III C-methyltransferase Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation	BG180662
119	PEX7	interactor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat	BG180662
120	PLK4	interactor	ABC1 (PF03109, IPR004147): ABC1 family Pkinase (PF00069, IPR000719): Protein kinase domain POLO_box (PF00659, IPR000959): POLO box duplicated region DUF4520 (PF15016, IPR027865): Domain of unknown function (DUF4520)	BG180662
121	POC1A	interactor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat	BG180662
122	POC1B	interactor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
123	PPP1CC	oncoprotein	Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain	BG180662
124	PPP2CA	suppressor	Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain	BG180662
125	PPP2CB	suppressor	Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain	BG180662
126	PPP2R2A	interactor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
127	PPP2R2B	interactor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
128	PPP2R2C	suppressor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
129	PPP2R2D	interactor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
130	PPP4C	interactor	Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain	BG180662
131	PRKCDBP	suppressor	A1_Propeptide (PF07966, IPR012848): A1 Propeptide PTRF_SDPR (PF15237, IPR026752): PTRF/SDPR family	BG180662
132	PRPF4	interactor	PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_like (PF17005, IPR031544): WD40-like domain	BG180662
133	PRPF40A	interactor	FF (PF01846, IPR002713, SM00441): FF domain MCR_alpha (PF02249, IPR009047): Methyl-coenzyme M reductase alpha subunit, C-terminal domain Transformer (PF06495, IPR010519): Fruit fly transformer protein WW (PF00397, IPR001202, SM00456): WW domain YqzE (PF14038, IPR025622): YqzE-like protein SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6 SRRM_C (PF15230, IPR029360): Serine/arginine repetitive matrix protein C-terminus SOBP (PF15279, IPR026092): Sine oculis-binding protein IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal	BG180662
134	PSMA3	interactor	Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature	BG180662
135	PSMB8	interactor	Proteasome (PF00227, IPR001353): Proteasome subunit	BG180662
136	PSMC2	interactor	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)	BG180662
137	PSMC6	interactor	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) AAA_2 (PF07724, IPR013093): AAA domain (Cdc48 subfamily) TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain	BG180662
138	PSMD2	oncoprotein	PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat THAP (PF05485, IPR006612, SM00980): THAP domain HEAT_2 (PF13646): HEAT repeats	BG180662
139	PTPA	suppressor	PTPA (PF03095, IPR004327): Phosphotyrosyl phosphate activator (PTPA) protein	BG180662
140	RAD21	oncoprotein	Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box	BG180662
141	REL	oncoprotein	RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain	BG180662
142	RFWD2	suppressor	Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein IncA (PF04156, IPR007285): IncA protein WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) WD40_like (PF17005, IPR031544): WD40-like domain	BG180662
143	RFWD3	interactor	OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
144	RPS3	interactor	KH_2 (PF07650, IPR004044): KH domain Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain	BG180662
145	RPS6KB2	interactor	Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain	BG180662
146	RUNX1	suppressor	Runt (PF00853, IPR013524): Runt domain RunxI (PF08504, IPR013711): Runx inhibition domain DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037)	BG180662
147	SEC31B	interactor	SRA1 (PF07304, IPR009917): Steroid receptor RNA activator (SRA1) ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain Sec16_C (PF12931, IPR024298): Sec23-binding domain of Sec16	BG180662
148	SF3B3	interactor	CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term	BG180662
149	SHC1	oncoprotein	PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) SH2 (PF00017, IPR000980, SM00252): SH2 domain	BG180662
150	SIRT7	interactor	DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family	BG180662
151	SMURF1	interactor	C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)	BG180662
152	SNW1	interactor	SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain	BG180662
153	SP1	interactor	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1	BG180662
154	SSR1	interactor	TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit	BG180662
155	SSSCA1	interactor	Auto_anti-p27 (PF06677, IPR009563): Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27)	BG180662
156	STAU1	interactor	dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain	BG180662
157	STK24	interactor	DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241) Pkinase (PF00069, IPR000719): Protein kinase domain	BG180662
158	STRN	oncoprotein	CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) Nucleoporin_N (PF08801, IPR014908): Nup133 N terminal like Striatin (PF08232, IPR013258): Striatin family WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
159	STRN3	interactor	Striatin (PF08232, IPR013258): Striatin family WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
160	TCP1	interactor	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family	BG180662
161	TP53	suppressor	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif	BG180662
162	TRIM28	interactor	ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2	BG180662
163	TSSK6	interactor	Pkinase (PF00069, IPR000719): Protein kinase domain	BG180662
164	TTLL3	oncoprotein	TTL (PF03133, IPR004344): Tubulin-tyrosine ligase family	BG180662
165	TUBA1B	interactor	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain	BG180662
166	TUBA1C	interactor	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain	BG180662
167	TUBA3E	interactor	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain	BG180662
168	TUBAL3	interactor	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain	BG180662
169	TUBB	interactor	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain	BG180662
170	TUBB2A	interactor	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain	BG180662
171	TUBB2B	interactor	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain	BG180662
172	TUBG1	interactor	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain	BG180662
173	TXNL1	interactor	PITH (PF06201, IPR010400): PITH domain Thioredoxin (PF00085, IPR013766): Thioredoxin	BG180662
174	TYK2	interactor	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase	BG180662
175	U2AF2	interactor	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein	BG180662
176	UBC	interactor	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family	BG180662
177	VAV2	oncoprotein	PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain CotJB (PF12652, IPR024207): CotJB protein	BG180662
178	VCAM1	interactor	C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain	BG180662
179	VCP	interactor	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)	BG180662
180	VHL	suppressor	Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): VHL beta domain VHL_C (PF17211): VHL box domain	BG180662
181	VRK2	interactor	Pkinase (PF00069, IPR000719): Protein kinase domain VP_N-CPKC (PF11475, IPR021573): Virion protein N terminal domain	BG180662
182	WDR76	interactor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat SPATIAL (PF15256): SPATIAL	BG180662
183	WDR83	interactor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
184	WRAP53	oncoprotein	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
185	WRAP73	interactor	eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A IKI3 (PF04762, IPR006849): IKI3 family WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2555 (PF10742, IPR019678): Protein of unknown function (DUF2555) ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
186	WWOX	suppressor	adh_short (PF00106, IPR002198): short chain dehydrogenase WW (PF00397, IPR001202, SM00456): WW domain	BG180662
187	XIAP	interactor	BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)	BG180662

B a c k    t o    T o p ⇑