1 |
ELF1 | parental protein | 7 | 0.333 | 388.196 | Ets (PF00178, IPR000418, SM00413): Ets-domain PAPA-1 (PF04795, IPR006880): PAPA-1-like conserved region Elf-1_N (PF12310, IPR022084): Transcription factor protein N terminal |
2 |
CCT2 | parental protein | 182 | 0.125 | 10829.103 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
3 |
ACTA1 | interactor | 13 | 0.462 | 8.005 | Actin (PF00022, IPR004000, SM00268): Actin |
4 |
ACTB | oncoprotein | 36 | 0.343 | 91.992 | Actin (PF00022, IPR004000, SM00268): Actin |
5 |
ACTL6A | interactor | 16 | 0.683 | 5.539 | Actin (PF00022, IPR004000, SM00268): Actin |
6 |
ACTR1B | interactor | 8 | 0.929 | 0.314 | Actin (PF00022, IPR004000, SM00268): Actin |
7 |
ACTR2 | interactor | 22 | 0.623 | 14.631 | Actin (PF00022, IPR004000, SM00268): Actin |
8 |
AHSA1 | interactor | 21 | 0.533 | 20.148 | Aha1_N (PF09229, IPR015310, SM01000): Activator of Hsp90 ATPase, N-terminal AHSA1 (PF08327, IPR013538): Activator of Hsp90 ATPase homolog 1-like protein |
9 |
ALKBH3 | interactor | 9 | 0.556 | 2.809 | 2OG-FeII_Oxy_2 (PF13532, IPR027450): 2OG-Fe(II) oxygenase superfamily |
10 |
AMBRA1 | interactor | 16 | 0.575 | 10.571 | Acyl_CoA_thio (PF02551, IPR025652): Acyl-CoA thioesterase eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Spt20 (PF12090, IPR021950): Spt20 family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
11 |
ARMC6 | interactor | 12 | 0.667 | 6.497 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Mis14 (PF08641, IPR013950): Kinetochore protein Mis14 like Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain |
12 |
ATF2 | oncoprotein | 17 | 0.367 | 68.628 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type |
13 |
ATG16L1 | interactor | 8 | 0.667 | 1.072 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2332 (PF10094, IPR011200): Uncharacterized protein conserved in bacteria (DUF2332) Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 |
14 |
ATP6V1B1 | interactor | 2 | 1.000 | 0 | ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain DUF3533 (PF12051, IPR022703): Protein of unknown function (DUF3533) |
15 |
B9D1 | interactor | 9 | 0.972 | 0.250 | Ribosomal_L40e (PF01020, IPR001975): Ribosomal L40e family |
16 |
BTRC | oncoprotein | 31 | 0.331 | 221.333 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like |
17 |
BUB1B | oncoprotein | 12 | 0.436 | 7.547 | Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1 Mad3_BUB1_II (PF08171, IPR012572): Mad3/BUB1 homology region 2 Pkinase (PF00069, IPR000719): Protein kinase domain XhlA (PF10779, IPR019715): Haemolysin XhlA CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167 |
18 |
BUB3 | interactor | 17 | 0.596 | 8.899 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
19 |
C11orf54 | interactor | 2 | 1.000 | 0 | DUF1907 (PF08925, IPR015021, SM01168): Domain of Unknown Function (DUF1907) |
20 |
CAMKMT | interactor | 8 | 0.571 | 1.391 | Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase |
21 |
CASP7 | interactor | 6 | 0.300 | 8.809 | Peptidase_C14 (PF00656, IPR011600): Caspase domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
22 |
CCDC8 | interactor | 29 | 0.532 | 26.765 | Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA |
23 |
CCNE1 | oncoprotein | 9 | 0.417 | 4.695 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain |
24 |
CCT3 | interactor | 119 | 0.170 | 1959.515 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
25 |
CCT4 | interactor | 112 | 0.175 | 1668.347 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
26 |
CCT5 | interactor | 97 | 0.207 | 1066.914 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
27 |
CCT6A | interactor | 113 | 0.176 | 1738.100 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
28 |
CCT6B | interactor | 37 | 0.300 | 203.522 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
29 |
CCT7 | interactor | 107 | 0.177 | 1627.768 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
30 |
CCT8 | interactor | 100 | 0.215 | 1042.900 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
31 |
CDC20 | oncoprotein | 27 | 0.526 | 33.924 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
32 |
CDC5L | interactor | 46 | 0.431 | 130.604 | OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
33 |
CDK15 | interactor | 6 | 0.667 | 0.959 | Pkinase (PF00069, IPR000719): Protein kinase domain ACT_5 (PF13710): ACT domain |
34 |
CDK2 | suppressor | 52 | 0.322 | 476.846 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
35 |
CDK5 | oncoprotein | 15 | 0.659 | 4.798 | Pkinase (PF00069, IPR000719): Protein kinase domain |
36 |
CDK7 | oncoprotein | 8 | 0.762 | 1.297 | Pkinase (PF00069, IPR000719): Protein kinase domain |
37 |
CETN2 | interactor | 7 | 1.000 | 0 | EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
38 |
COPS5 | protein found in more fusions | 45 | 0.379 | 184.514 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
39 |
CRY2 | protein found in more fusions | 20 | 0.503 | 16.807 | DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase |
40 |
CTTNBP2 | interactor | 14 | 0.769 | 8.195 | Carmo_coat_C (PF08462, IPR013669): Carmovirus coat protein CortBP2 (PF09727, IPR019131): Cortactin-binding protein-2 Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour |
41 |
CUL1 | suppressor | 47 | 0.384 | 153.987 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
42 |
CUL3 | protein found in more fusions | 68 | 0.290 | 626.377 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
43 |
CUL7 | protein found in more fusions | 40 | 0.417 | 126.510 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
44 |
CYB5B | interactor | 2 | 1.000 | 0 | Cyt-b5 (PF00173, IPR001199, SM01117): Cytochrome b5-like Heme/Steroid binding domain MIP (PF00230, IPR000425): Major intrinsic protein |
45 |
DCAF5 | interactor | 7 | 0.905 | 0.187 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2634 (PF10934, IPR020288): Protein of unknown function (DUF2634) IMUP (PF15761, IPR026621): Immortalisation up-regulated protein |
46 |
DCAF7 | interactor | 11 | 0.891 | 1.186 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
47 |
DDB2 | suppressor | 14 | 0.769 | 4.606 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
48 |
DNAJA1 | interactor | 44 | 0.328 | 190.525 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain |
49 |
DNAJA4 | interactor | 12 | 0.636 | 4.555 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain |
50 |
EEF1D | protein found in more fusions | 19 | 0.464 | 11.107 | EF1_GNE (PF00736, IPR014038, SM00888): EF-1 guanine nucleotide exchange domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region |
51 |
EEF2 | interactor | 30 | 0.372 | 90.362 | EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II |
52 |
ENDOV | interactor | 1 | 0 | 0 | Endonuclease_5 (PF04493, IPR007581): Endonuclease V |
53 |
ERLIN2 | interactor | 13 | 0.423 | 16.175 | Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family DUF4346 (PF14251, IPR025595): Domain of unknown function (DUF4346) |
54 |
ESR1 | suppressor | 35 | 0.383 | 147.475 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
55 |
FAM86B2 | interactor | 11 | 0.818 | 1.244 | Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase FAM86 (PF14904, IPR029426): Family of unknown function |
56 |
FBXO6 | interactor | 38 | 0.378 | 92.649 | FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like |
57 |
FBXW4 | oncoprotein | 11 | 0.800 | 1.383 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat F-box-like (PF12937, IPR001810): F-box-like F-box_4 (PF15966, IPR001810): F-box |
58 |
FBXW8 | interactor | 15 | 0.629 | 6.371 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like |
59 |
FCHSD2 | interactor | 4 | 1.000 | 0 | Cortex-I_coil (PF09304, IPR015383): Cortexillin I, coiled coil DivIC (PF04977, IPR007060): Septum formation initiator FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain DUF4665 (PF15679, IPR031389): Domain of unknown function (DUF4665) Rit1_C (PF17184): Rit1 N-terminal domain |
60 |
FN1 | oncoprotein | 38 | 0.404 | 125.618 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
61 |
FUS | suppressor | 39 | 0.528 | 62.800 | Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Limkain-b1 (PF11608, IPR024582): Limkain b1 FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
62 |
FYCO1 | interactor | 6 | 1.000 | 0 | Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger HAP1_N (PF04849, IPR006933): HAP1 N-terminal conserved region RUN (PF02759, IPR004012, SM00593): RUN domain Sec8_exocyst (PF04048, IPR007191): Sec8 exocyst complex component specific domain Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Spectrin (PF00435, IPR002017): Spectrin repeat Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal TSC22 (PF01166, IPR000580): TSC-22/dip/bun family bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like GOLD_2 (PF13897, IPR009038): Golgi-dynamics membrane-trafficking DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) DUF4578 (PF15147, IPR028106): Domain of unknown function (DUF4578) HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
63 |
GAN | protein found in more fusions | 20 | 0.503 | 17.166 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif |
64 |
GPR37 | interactor | 6 | 0.933 | 0.065 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) |
65 |
GRB2 | oncoprotein | 34 | 0.487 | 133.988 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093) |
66 |
GSPT1 | oncoprotein | 7 | 0.429 | 8.983 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region |
67 |
GSPT2 | interactor | 2 | 1.000 | 0 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region |
68 |
GTF2I | interactor | 15 | 0.505 | 10.107 | GTF2I (PF02946, IPR004212): GTF2I-like repeat |
69 |
HDAC1 | suppressor | 32 | 0.370 | 288.201 | FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
70 |
HDAC3 | suppressor | 20 | 0.520 | 120.996 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
71 |
HDAC5 | protein found in more fusions | 35 | 0.456 | 87.764 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4 |
72 |
HMGA1 | oncoprotein | 13 | 0.372 | 147.162 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF2239 (PF09998, IPR018715): Uncharacterized protein conserved in bacteria (DUF2239) |
73 |
HOXC13 | oncoprotein | 1 | 0 | 0 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain HoxA13_N (PF12284, IPR022067): Hox protein A13 N terminal |
74 |
HSP90AA1 | oncoprotein | 70 | 0.240 | 664.940 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
75 |
HSP90AB1 | oncoprotein | 56 | 0.306 | 330.480 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
76 |
HSP90B1 | suppressor | 27 | 0.436 | 37.542 | CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region |
77 |
HSPA4 | interactor | 45 | 0.295 | 349.355 | Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5 |
78 |
HSPE1 | interactor | 17 | 0.537 | 13.444 | Cpn10 (PF00166, IPR020818, SM00883): Chaperonin 10 Kd subunit |
79 |
HSPH1 | oncoprotein | 20 | 0.416 | 34.286 | HSP70 (PF00012, IPR013126): Hsp70 protein SICA_alpha (PF12887, IPR024290): SICA extracellular alpha domain |
80 |
HUWE1 | oncoprotein | 49 | 0.418 | 149.272 | BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414) |
81 |
IGBP1 | interactor | 12 | 0.955 | 0.701 | TAP42 (PF04177, IPR007304): TAP42-like family |
82 |
IKBKE | interactor | 13 | 0.652 | 7.120 | IncA (PF04156, IPR007285): IncA protein Pkinase (PF00069, IPR000719): Protein kinase domain SlyX (PF04102, IPR007236): SlyX zf-RING_9 (PF13901, IPR025258): Putative zinc-RING and/or ribbon |
83 |
ILK | suppressor | 24 | 0.510 | 29.782 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
84 |
IQGAP1 | interactor | 29 | 0.379 | 55.120 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF87 (PF01935, IPR002789): Domain of unknown function DUF87 IDEAL (PF08858, IPR014957, SM00914): IDEAL domain IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase RasGAP_C (PF03836, IPR000593): RasGAP C-terminus WW (PF00397, IPR001202, SM00456): WW domain |
85 |
IRAK1 | interactor | 20 | 0.602 | 8.603 | Death (PF00531, IPR000488, SM00005): Death domain Pkinase (PF00069, IPR000719): Protein kinase domain |
86 |
ISG15 | suppressor | 13 | 0.423 | 10.978 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
87 |
ITGA4 | interactor | 33 | 0.490 | 43.892 | FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha |
88 |
JAK3 | oncoprotein | 7 | 1.000 | 0 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain |
89 |
KIF21A | interactor | 12 | 0.879 | 0.867 | DUF1690 (PF07956, IPR012471): Protein of Unknown function (DUF1690) DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Strep_SA_rep (PF06696, IPR009578): Streptococcal surface antigen repeat TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding TSNAXIP1_N (PF15739, IPR032755): Translin-associated factor X-interacting N-terminus DUF4746 (PF15928, IPR031827): Domain of unknown function (DUF4746) HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
90 |
KPNA4 | interactor | 14 | 0.659 | 7.922 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat IBB (PF01749, IPR002652): Importin beta binding domain Arm_3 (PF16186, IPR032413): Atypical Arm repeat |
91 |
KRAS | oncoprotein | 14 | 0.333 | 20.497 | Ras (PF00071, IPR001806, SM00173): Ras family |
92 |
LFNG | oncoprotein | 3 | 1.000 | 0 | Fringe (PF02434, IPR003378): Fringe-like |
93 |
LGALS3BP | oncoprotein | 30 | 0.589 | 22.665 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain SRCR_2 (PF15494, IPR017448): Scavenger receptor cysteine-rich domain |
94 |
LRRK1 | interactor | 6 | 0.800 | 0.271 | Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase Pkinase (PF00069, IPR000719): Protein kinase domain TniB (PF05621, IPR008868): Bacterial TniB protein Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat COR (PF16095, IPR032171): C-terminal of Roc, COR, domain |
95 |
MAPK10 | suppressor | 7 | 0.600 | 1.820 | Pkinase (PF00069, IPR000719): Protein kinase domain |
96 |
MAPK8 | oncoprotein | 16 | 0.505 | 55.273 | DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530) Pkinase (PF00069, IPR000719): Protein kinase domain |
97 |
MCM2 | oncoprotein | 50 | 0.402 | 181.404 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
98 |
MEPCE | interactor | 13 | 0.513 | 7.108 | Bin3 (PF06859, IPR010675): Bicoid-interacting protein 3 (Bin3) Methyltransf_23 (PF13489): Methyltransferase domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 DLEU7 (PF15760, IPR031510): Leukemia-associated protein 7 |
99 |
METTL18 | interactor | 11 | 0.727 | 1.960 | Methyltransf_23 (PF13489): Methyltransferase domain |
100 |
METTL21B | interactor | 16 | 0.650 | 7.157 | Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase |
101 |
MKS1 | interactor | 9 | 0.861 | 0.783 | B9-C2 (PF07162, IPR010796): Ciliary basal body-associated, B9 protein |
102 |
MLST8 | interactor | 4 | 0.833 | 0.477 | Hira (PF07569, IPR011494): TUP1-like enhancer of split WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 |
103 |
MOB4 | interactor | 15 | 0.867 | 2.819 | Mob1_phocein (PF03637, IPR005301): Mob1/phocein family |
104 |
MYC | oncoprotein | 45 | 0.350 | 391.024 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
105 |
NEDD1 | interactor | 16 | 0.642 | 11.541 | NRBF2 (PF08961, IPR015056): Nuclear receptor-binding factor 2, autophagy regulator eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A FliM (PF02154, IPR001689): Flagellar motor switch protein FliM WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Mto2_bdg (PF12808, IPR024545): Micro-tubular organiser Mto1 C-term Mto2-binding region ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
106 |
NFKB1 | suppressor | 16 | 0.333 | 226.407 | Death (PF00531, IPR000488, SM00005): Death domain GHMP_kinases_C (PF08544, IPR013750): GHMP kinases C terminal RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
107 |
NFYA | interactor | 9 | 0.444 | 76.688 | CBFB_NFYA (PF02045, IPR001289): CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B MSP1_C (PF07462, IPR010901): Merozoite surface protein 1 (MSP1) C-terminus FixG_C (PF11614, IPR032879): IG-like fold at C-terminal of FixG, putative oxidoreductase DUF4237 (PF14021, IPR025331): Protein of unknown function (DUF4237) |
108 |
NIPSNAP1 | interactor | 15 | 0.733 | 3.135 | NIPSNAP (PF07978, IPR012577): NIPSNAP |
109 |
NOS2 | interactor | 23 | 0.545 | 12.309 | FAD_binding_1 (PF00667, IPR003097): FAD binding domain Flavodoxin_1 (PF00258, IPR008254): Flavodoxin NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain |
110 |
NPM1 | suppressor | 49 | 0.395 | 196.723 | Nucleoplasmin (PF03066): Nucleoplasmin/nucleophosmin domain SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain |
111 |
NSFL1C | interactor | 9 | 0.528 | 10.103 | SEP (PF08059, IPR012989, SM00553): SEP domain UBX (PF00789, IPR001012, SM00166): UBX domain UBA_4 (PF14555): UBA-like domain |
112 |
NSMAF | interactor | 9 | 0.861 | 0.395 | Beach (PF02138, IPR000409, SM01026): Beige/BEACH domain GRAM (PF02893, IPR004182, SM00568): GRAM domain NABP (PF07990, IPR012940): Nucleic acid binding protein NABP WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain PH_BEACH (PF14844, IPR023362): PH domain associated with Beige/BEACH |
113 |
NTRK1 | oncoprotein | 68 | 0.315 | 468.656 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
114 |
NXF1 | interactor | 37 | 0.246 | 289.016 | NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat |
115 |
OBSL1 | interactor | 36 | 0.432 | 97.433 | BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
116 |
PACRG | suppressor | 15 | 0.657 | 7.070 | ParcG (PF10274, IPR019399): Parkin co-regulated protein |
117 |
PAN2 | interactor | 18 | 0.484 | 28.349 | RNase_T (PF00929, IPR013520): Exonuclease UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase WD40_like (PF17005, IPR031544): WD40-like domain |
118 |
PARK2 | suppressor | 30 | 0.384 | 105.063 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
119 |
PCK1 | interactor | 10 | 0.489 | 2.326 | PEPCK (PF00821, IPR008209): Phosphoenolpyruvate carboxykinase |
120 |
PDK3 | interactor | 9 | 1.000 | 0 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 (PF10436, IPR018955): Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase |
121 |
PEX14 | protein found in more fusions | 14 | 0.564 | 6.737 | HemX (PF04375, IPR007470): HemX, putative uroporphyrinogen-III C-methyltransferase Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation |
122 |
PEX7 | interactor | 9 | 0.972 | 0.182 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
123 |
PLK4 | interactor | 5 | 1.000 | 0 | ABC1 (PF03109, IPR004147): ABC1 family Pkinase (PF00069, IPR000719): Protein kinase domain POLO_box (PF00659, IPR000959): POLO box duplicated region DUF4520 (PF15016, IPR027865): Domain of unknown function (DUF4520) |
124 |
POC1A | interactor | 10 | 0.711 | 5.961 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
125 |
POC1B | interactor | 3 | 0.667 | 0.242 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
126 |
PPP1CC | oncoprotein | 18 | 0.614 | 10.004 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
127 |
PPP2CA | suppressor | 39 | 0.449 | 106.489 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
128 |
PPP2CB | suppressor | 25 | 0.630 | 27.025 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
129 |
PPP2R2A | interactor | 19 | 0.754 | 6.323 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
130 |
PPP2R2B | interactor | 15 | 0.848 | 2.499 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
131 |
PPP2R2C | suppressor | 13 | 0.833 | 3.273 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
132 |
PPP2R2D | interactor | 16 | 0.850 | 3.397 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
133 |
PPP4C | interactor | 20 | 0.642 | 81.337 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
134 |
PRKCDBP | suppressor | 2 | 1.000 | 0 | A1_Propeptide (PF07966, IPR012848): A1 Propeptide PTRF_SDPR (PF15237, IPR026752): PTRF/SDPR family |
135 |
PRPF4 | interactor | 22 | 0.667 | 14.940 | PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_like (PF17005, IPR031544): WD40-like domain |
136 |
PRPF40A | protein found in more fusions | 15 | 0.593 | 6.067 | FF (PF01846, IPR002713, SM00441): FF domain MCR_alpha (PF02249, IPR009047): Methyl-coenzyme M reductase alpha subunit, C-terminal domain Transformer (PF06495, IPR010519): Fruit fly transformer protein WW (PF00397, IPR001202, SM00456): WW domain YqzE (PF14038, IPR025622): YqzE-like protein SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6 SRRM_C (PF15230, IPR029360): Serine/arginine repetitive matrix protein C-terminus SOBP (PF15279, IPR026092): Sine oculis-binding protein IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal |
137 |
PSMA3 | interactor | 33 | 0.427 | 83.256 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
138 |
PSMB8 | interactor | 6 | 1.000 | 0 | Proteasome (PF00227, IPR001353): Proteasome subunit |
139 |
PSMC2 | protein found in more fusions | 34 | 0.430 | 82.332 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) |
140 |
PSMC6 | interactor | 24 | 0.415 | 37.829 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) AAA_2 (PF07724, IPR013093): AAA domain (Cdc48 subfamily) TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain |
141 |
PSMD2 | oncoprotein | 36 | 0.243 | 159.049 | PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat THAP (PF05485, IPR006612, SM00980): THAP domain HEAT_2 (PF13646): HEAT repeats |
142 |
PTPA | suppressor | 12 | 0.727 | 15.123 | PTPA (PF03095, IPR004327): Phosphotyrosyl phosphate activator (PTPA) protein |
143 |
RAD21 | oncoprotein | 17 | 0.515 | 13.319 | Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
144 |
REL | oncoprotein | 10 | 0.244 | 104.871 | RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
145 |
RFWD2 | suppressor | 14 | 0.821 | 1.553 | Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein IncA (PF04156, IPR007285): IncA protein WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) WD40_like (PF17005, IPR031544): WD40-like domain |
146 |
RFWD3 | interactor | 12 | 0.682 | 1.988 | OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
147 |
RPS3 | interactor | 40 | 0.324 | 132.219 | KH_2 (PF07650, IPR004044): KH domain Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain |
148 |
RPS6KB2 | interactor | 26 | 0.397 | 37.274 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
149 |
RUNX1 | suppressor | 6 | 0.200 | 42.406 | Runt (PF00853, IPR013524): Runt domain RunxI (PF08504, IPR013711): Runx inhibition domain DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037) |
150 |
SEC31B | interactor | 9 | 0.917 | 0.508 | SRA1 (PF07304, IPR009917): Steroid receptor RNA activator (SRA1) ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain Sec16_C (PF12931, IPR024298): Sec23-binding domain of Sec16 |
151 |
SF3B3 | interactor | 22 | 0.489 | 28.093 | CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term |
152 |
SHC1 | oncoprotein | 22 | 0.414 | 36.617 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) SH2 (PF00017, IPR000980, SM00252): SH2 domain |
153 |
SIRT7 | interactor | 25 | 0.427 | 34.515 | DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family |
154 |
SMURF1 | interactor | 21 | 0.458 | 15.102 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
155 |
SNW1 | protein found in more fusions | 47 | 0.375 | 201.781 | SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain |
156 |
SP1 | protein found in more fusions | 21 | 0.305 | 265.195 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
157 |
SSR1 | interactor | 11 | 0.764 | 1.561 | TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit |
158 |
SSSCA1 | interactor | 7 | 0.533 | 2.268 | Auto_anti-p27 (PF06677, IPR009563): Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) |
159 |
STAU1 | protein found in more fusions | 25 | 0.453 | 27.495 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain |
160 |
STK24 | interactor | 19 | 0.712 | 14.004 | DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241) Pkinase (PF00069, IPR000719): Protein kinase domain |
161 |
STRN | oncoprotein | 17 | 0.853 | 3.791 | CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) Nucleoporin_N (PF08801, IPR014908): Nup133 N terminal like Striatin (PF08232, IPR013258): Striatin family WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
162 |
STRN3 | interactor | 17 | 0.824 | 5.599 | Striatin (PF08232, IPR013258): Striatin family WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
163 |
TCF3 | suppressor | 4 | 0.333 | 21.639 | CDC45 (PF02724, IPR003874): CDC45-like protein HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682) |
164 |
TCP1 | interactor | 111 | 0.191 | 1645.220 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
165 |
TP53 | suppressor | 61 | 0.319 | 542.752 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
166 |
TRIM28 | protein found in more fusions | 39 | 0.373 | 98.338 | ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2 |
167 |
TSSK6 | interactor | 10 | 0.733 | 0.794 | Pkinase (PF00069, IPR000719): Protein kinase domain |
168 |
TTLL3 | oncoprotein | 7 | 1.000 | 0 | TTL (PF03133, IPR004344): Tubulin-tyrosine ligase family |
169 |
TUBA1B | interactor | 21 | 0.367 | 47.553 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
170 |
TUBA1C | interactor | 37 | 0.521 | 54.287 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
171 |
TUBA3E | interactor | 6 | 0.867 | 0.458 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
172 |
TUBAL3 | interactor | 8 | 0.714 | 1.290 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
173 |
TUBB | interactor | 50 | 0.309 | 234.190 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
174 |
TUBB2A | interactor | 20 | 0.300 | 36.830 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
175 |
TUBB2B | interactor | 20 | 0.511 | 21.153 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
176 |
TUBG1 | protein found in more fusions | 31 | 0.563 | 35.130 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
177 |
TXNL1 | interactor | 9 | 0.722 | 1.627 | PITH (PF06201, IPR010400): PITH domain Thioredoxin (PF00085, IPR013766): Thioredoxin |
178 |
TYK2 | interactor | 14 | 0.654 | 5.154 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
179 |
U2AF2 | protein found in more fusions | 32 | 0.488 | 52.432 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
180 |
UBC | protein found in more fusions | 54 | 0.331 | 308.702 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
181 |
VAV2 | oncoprotein | 7 | 0.619 | 2.337 | PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain CotJB (PF12652, IPR024207): CotJB protein |
182 |
VCAM1 | interactor | 31 | 0.477 | 35.937 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
183 |
VCP | protein found in more fusions | 64 | 0.359 | 450.742 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944) |
184 |
VHL | suppressor | 26 | 0.557 | 57.013 | Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): VHL beta domain VHL_C (PF17211): VHL box domain |
185 |
VRK2 | interactor | 6 | 0.867 | 0.448 | Pkinase (PF00069, IPR000719): Protein kinase domain VP_N-CPKC (PF11475, IPR021573): Virion protein N terminal domain |
186 |
WDR76 | interactor | 8 | 0.821 | 0.228 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat SPATIAL (PF15256): SPATIAL |
187 |
WDR83 | interactor | 11 | 0.836 | 2.345 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
188 |
WRAP53 | oncoprotein | 10 | 0.978 | 0.222 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
189 |
WRAP73 | interactor | 7 | 0.467 | 4.227 | eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A IKI3 (PF04762, IPR006849): IKI3 family WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2555 (PF10742, IPR019678): Protein of unknown function (DUF2555) ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
190 |
WWOX | suppressor | 14 | 0.473 | 12.329 | adh_short (PF00106, IPR002198): short chain dehydrogenase WW (PF00397, IPR001202, SM00456): WW domain |
191 |
XIAP | interactor | 7 | 0.400 | 5.870 | BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |