Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins ELF1, CCT2 (from a repository: Sat Aug 8 13:06:55 2020)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 191 The number (and %) of the onco-proteins 53 (27.75 %) The number (and %) of the tumor suppressors 26 (13.61 %) Total number of binary PPIs (saturation %) 2377 (13.10 %) The number (and %) of affected PPIs 189 (7.95 %) The number of possible different fusions 36 PPI diameter 5 PPI radius 3 The average degree of PPI 24.105 Assortativity coefficient -0.2933 The network average Clustering coefficient 0.563 The number (and %) of a zero Clustering coefficients 2 (1.05 %) The number (and %) of a zero Betweenness Centrality 16 (8.38 %)

ACTIVE INTERACTORS MISSING INTERACTORS (in fusions)

List of the fusions
PPI for parental proteins: ELF1,CCT2	All fusions : BG180662;
Proteins found in more fusions	U2AF2 (see 2 fusions); NPM1 (see 1 fusions); CUL1 (see 3 fusions); GRB2 (see 1 fusions); LGALS3BP (see 2 fusions); VHL (see 1 fusions); GAN (see 1 fusions); HDAC5 (see 1 fusions); SNW1 (see 1 fusions); VCP (see 4 fusions); HSP90AA1 (see 2 fusions); HUWE1 (see 2 fusions); HSP90AB1 (see 1 fusions); EEF1D (see 3 fusions); TCF3 (see 4 fusions); SHC1 (see 1 fusions); TUBG1 (see 1 fusions); PSMC2 (see 1 fusions); STAU1 (see 2 fusions); CUL7 (see 2 fusions); CUL3 (see 1 fusions); MYC (see 1 fusions); RUNX1 (see 1 fusions); ACTB (see 3 fusions); COPS5 (see 1 fusions); PEX14 (see 1 fusions); UBC (see 1 fusions); PRPF40A (see 2 fusions); TP53 (see 3 fusions); ILK (see 1 fusions); CRY2 (see 3 fusions); TRIM28 (see 1 fusions); NFKB1 (see 2 fusions); SP1 (see 1 fusions); MCM2 (see 1 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	ELF1	parental protein	7	0.333	388.196	Ets (PF00178, IPR000418, SM00413): Ets-domain PAPA-1 (PF04795, IPR006880): PAPA-1-like conserved region Elf-1_N (PF12310, IPR022084): Transcription factor protein N terminal
2	CCT2	parental protein	182	0.125	10829.103	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
3	ACTA1	interactor	13	0.462	8.005	Actin (PF00022, IPR004000, SM00268): Actin
4	ACTB	oncoprotein	36	0.343	91.992	Actin (PF00022, IPR004000, SM00268): Actin
5	ACTL6A	interactor	16	0.683	5.539	Actin (PF00022, IPR004000, SM00268): Actin
6	ACTR1B	interactor	8	0.929	0.314	Actin (PF00022, IPR004000, SM00268): Actin
7	ACTR2	interactor	22	0.623	14.631	Actin (PF00022, IPR004000, SM00268): Actin
8	AHSA1	interactor	21	0.533	20.148	Aha1_N (PF09229, IPR015310, SM01000): Activator of Hsp90 ATPase, N-terminal AHSA1 (PF08327, IPR013538): Activator of Hsp90 ATPase homolog 1-like protein
9	ALKBH3	interactor	9	0.556	2.809	2OG-FeII_Oxy_2 (PF13532, IPR027450): 2OG-Fe(II) oxygenase superfamily
10	AMBRA1	interactor	16	0.575	10.571	Acyl_CoA_thio (PF02551, IPR025652): Acyl-CoA thioesterase eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Spt20 (PF12090, IPR021950): Spt20 family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
11	ARMC6	interactor	12	0.667	6.497	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Mis14 (PF08641, IPR013950): Kinetochore protein Mis14 like Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
12	ATF2	oncoprotein	17	0.367	68.628	bZIP_1 (PF00170, IPR004827): bZIP transcription factor zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
13	ATG16L1	interactor	8	0.667	1.072	ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2332 (PF10094, IPR011200): Uncharacterized protein conserved in bacteria (DUF2332) Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
14	ATP6V1B1	interactor	2	1.000	0	ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain DUF3533 (PF12051, IPR022703): Protein of unknown function (DUF3533)
15	B9D1	interactor	9	0.972	0.250	Ribosomal_L40e (PF01020, IPR001975): Ribosomal L40e family
16	BTRC	oncoprotein	31	0.331	221.333	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like
17	BUB1B	oncoprotein	12	0.436	7.547	Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1 Mad3_BUB1_II (PF08171, IPR012572): Mad3/BUB1 homology region 2 Pkinase (PF00069, IPR000719): Protein kinase domain XhlA (PF10779, IPR019715): Haemolysin XhlA CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
18	BUB3	interactor	17	0.596	8.899	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
19	C11orf54	interactor	2	1.000	0	DUF1907 (PF08925, IPR015021, SM01168): Domain of Unknown Function (DUF1907)
20	CAMKMT	interactor	8	0.571	1.391	Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase
21	CASP7	interactor	6	0.300	8.809	Peptidase_C14 (PF00656, IPR011600): Caspase domain PRIMA1 (PF16101): Proline-rich membrane anchor 1
22	CCDC8	interactor	29	0.532	26.765	Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA
23	CCNE1	oncoprotein	9	0.417	4.695	Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
24	CCT3	interactor	119	0.170	1959.515	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
25	CCT4	interactor	112	0.175	1668.347	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
26	CCT5	interactor	97	0.207	1066.914	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
27	CCT6A	interactor	113	0.176	1738.100	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
28	CCT6B	interactor	37	0.300	203.522	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
29	CCT7	interactor	107	0.177	1627.768	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
30	CCT8	interactor	100	0.215	1042.900	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
31	CDC20	oncoprotein	27	0.526	33.924	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
32	CDC5L	interactor	46	0.431	130.604	OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
33	CDK15	interactor	6	0.667	0.959	Pkinase (PF00069, IPR000719): Protein kinase domain ACT_5 (PF13710): ACT domain
34	CDK2	suppressor	52	0.322	476.846	Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain
35	CDK5	oncoprotein	15	0.659	4.798	Pkinase (PF00069, IPR000719): Protein kinase domain
36	CDK7	oncoprotein	8	0.762	1.297	Pkinase (PF00069, IPR000719): Protein kinase domain
37	CETN2	interactor	7	1.000	0	EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
38	COPS5	protein found in more fusions	45	0.379	184.514	JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
39	CRY2	protein found in more fusions	20	0.503	16.807	DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
40	CTTNBP2	interactor	14	0.769	8.195	Carmo_coat_C (PF08462, IPR013669): Carmovirus coat protein CortBP2 (PF09727, IPR019131): Cortactin-binding protein-2 Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour
41	CUL1	suppressor	47	0.384	153.987	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
42	CUL3	protein found in more fusions	68	0.290	626.377	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
43	CUL7	protein found in more fusions	40	0.417	126.510	ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
44	CYB5B	interactor	2	1.000	0	Cyt-b5 (PF00173, IPR001199, SM01117): Cytochrome b5-like Heme/Steroid binding domain MIP (PF00230, IPR000425): Major intrinsic protein
45	DCAF5	interactor	7	0.905	0.187	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2634 (PF10934, IPR020288): Protein of unknown function (DUF2634) IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
46	DCAF7	interactor	11	0.891	1.186	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
47	DDB2	suppressor	14	0.769	4.606	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
48	DNAJA1	interactor	44	0.328	190.525	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
49	DNAJA4	interactor	12	0.636	4.555	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
50	EEF1D	protein found in more fusions	19	0.464	11.107	EF1_GNE (PF00736, IPR014038, SM00888): EF-1 guanine nucleotide exchange domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
51	EEF2	interactor	30	0.372	90.362	EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II
52	ENDOV	interactor	1	0	0	Endonuclease_5 (PF04493, IPR007581): Endonuclease V
53	ERLIN2	interactor	13	0.423	16.175	Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family DUF4346 (PF14251, IPR025595): Domain of unknown function (DUF4346)
54	ESR1	suppressor	35	0.383	147.475	Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
55	FAM86B2	interactor	11	0.818	1.244	Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase FAM86 (PF14904, IPR029426): Family of unknown function
56	FBXO6	interactor	38	0.378	92.649	FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like
57	FBXW4	oncoprotein	11	0.800	1.383	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat F-box-like (PF12937, IPR001810): F-box-like F-box_4 (PF15966, IPR001810): F-box
58	FBXW8	interactor	15	0.629	6.371	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like
59	FCHSD2	interactor	4	1.000	0	Cortex-I_coil (PF09304, IPR015383): Cortexillin I, coiled coil DivIC (PF04977, IPR007060): Septum formation initiator FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain DUF4665 (PF15679, IPR031389): Domain of unknown function (DUF4665) Rit1_C (PF17184): Rit1 N-terminal domain
60	FN1	oncoprotein	38	0.404	125.618	fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
61	FUS	suppressor	39	0.528	62.800	Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Limkain-b1 (PF11608, IPR024582): Limkain b1 FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head
62	FYCO1	interactor	6	1.000	0	Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger HAP1_N (PF04849, IPR006933): HAP1 N-terminal conserved region RUN (PF02759, IPR004012, SM00593): RUN domain Sec8_exocyst (PF04048, IPR007191): Sec8 exocyst complex component specific domain Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Spectrin (PF00435, IPR002017): Spectrin repeat Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal TSC22 (PF01166, IPR000580): TSC-22/dip/bun family bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like GOLD_2 (PF13897, IPR009038): Golgi-dynamics membrane-trafficking DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) DUF4578 (PF15147, IPR028106): Domain of unknown function (DUF4578) HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
63	GAN	protein found in more fusions	20	0.503	17.166	BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif
64	GPR37	interactor	6	0.933	0.065	7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
65	GRB2	oncoprotein	34	0.487	133.988	SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
66	GSPT1	oncoprotein	7	0.429	8.983	GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
67	GSPT2	interactor	2	1.000	0	GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
68	GTF2I	interactor	15	0.505	10.107	GTF2I (PF02946, IPR004212): GTF2I-like repeat
69	HDAC1	suppressor	32	0.370	288.201	FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
70	HDAC3	suppressor	20	0.520	120.996	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
71	HDAC5	protein found in more fusions	35	0.456	87.764	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
72	HMGA1	oncoprotein	13	0.372	147.162	AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF2239 (PF09998, IPR018715): Uncharacterized protein conserved in bacteria (DUF2239)
73	HOXC13	oncoprotein	1	0	0	Homeobox (PF00046, IPR001356, SM00389): Homeobox domain HoxA13_N (PF12284, IPR022067): Hox protein A13 N terminal
74	HSP90AA1	oncoprotein	70	0.240	664.940	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
75	HSP90AB1	oncoprotein	56	0.306	330.480	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
76	HSP90B1	suppressor	27	0.436	37.542	CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region
77	HSPA4	interactor	45	0.295	349.355	Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
78	HSPE1	interactor	17	0.537	13.444	Cpn10 (PF00166, IPR020818, SM00883): Chaperonin 10 Kd subunit
79	HSPH1	oncoprotein	20	0.416	34.286	HSP70 (PF00012, IPR013126): Hsp70 protein SICA_alpha (PF12887, IPR024290): SICA extracellular alpha domain
80	HUWE1	oncoprotein	49	0.418	149.272	BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
81	IGBP1	interactor	12	0.955	0.701	TAP42 (PF04177, IPR007304): TAP42-like family
82	IKBKE	interactor	13	0.652	7.120	IncA (PF04156, IPR007285): IncA protein Pkinase (PF00069, IPR000719): Protein kinase domain SlyX (PF04102, IPR007236): SlyX zf-RING_9 (PF13901, IPR025258): Putative zinc-RING and/or ribbon
83	ILK	suppressor	24	0.510	29.782	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies)
84	IQGAP1	interactor	29	0.379	55.120	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF87 (PF01935, IPR002789): Domain of unknown function DUF87 IDEAL (PF08858, IPR014957, SM00914): IDEAL domain IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase RasGAP_C (PF03836, IPR000593): RasGAP C-terminus WW (PF00397, IPR001202, SM00456): WW domain
85	IRAK1	interactor	20	0.602	8.603	Death (PF00531, IPR000488, SM00005): Death domain Pkinase (PF00069, IPR000719): Protein kinase domain
86	ISG15	suppressor	13	0.423	10.978	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
87	ITGA4	interactor	33	0.490	43.892	FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
88	JAK3	oncoprotein	7	1.000	0	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain
89	KIF21A	interactor	12	0.879	0.867	DUF1690 (PF07956, IPR012471): Protein of Unknown function (DUF1690) DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Strep_SA_rep (PF06696, IPR009578): Streptococcal surface antigen repeat TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding TSNAXIP1_N (PF15739, IPR032755): Translin-associated factor X-interacting N-terminus DUF4746 (PF15928, IPR031827): Domain of unknown function (DUF4746) HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
90	KPNA4	interactor	14	0.659	7.922	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat IBB (PF01749, IPR002652): Importin beta binding domain Arm_3 (PF16186, IPR032413): Atypical Arm repeat
91	KRAS	oncoprotein	14	0.333	20.497	Ras (PF00071, IPR001806, SM00173): Ras family
92	LFNG	oncoprotein	3	1.000	0	Fringe (PF02434, IPR003378): Fringe-like
93	LGALS3BP	oncoprotein	30	0.589	22.665	BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain SRCR_2 (PF15494, IPR017448): Scavenger receptor cysteine-rich domain
94	LRRK1	interactor	6	0.800	0.271	Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase Pkinase (PF00069, IPR000719): Protein kinase domain TniB (PF05621, IPR008868): Bacterial TniB protein Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat COR (PF16095, IPR032171): C-terminal of Roc, COR, domain
95	MAPK10	suppressor	7	0.600	1.820	Pkinase (PF00069, IPR000719): Protein kinase domain
96	MAPK8	oncoprotein	16	0.505	55.273	DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530) Pkinase (PF00069, IPR000719): Protein kinase domain
97	MCM2	oncoprotein	50	0.402	181.404	AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
98	MEPCE	interactor	13	0.513	7.108	Bin3 (PF06859, IPR010675): Bicoid-interacting protein 3 (Bin3) Methyltransf_23 (PF13489): Methyltransferase domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 DLEU7 (PF15760, IPR031510): Leukemia-associated protein 7
99	METTL18	interactor	11	0.727	1.960	Methyltransf_23 (PF13489): Methyltransferase domain
100	METTL21B	interactor	16	0.650	7.157	Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase
101	MKS1	interactor	9	0.861	0.783	B9-C2 (PF07162, IPR010796): Ciliary basal body-associated, B9 protein
102	MLST8	interactor	4	0.833	0.477	Hira (PF07569, IPR011494): TUP1-like enhancer of split WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
103	MOB4	interactor	15	0.867	2.819	Mob1_phocein (PF03637, IPR005301): Mob1/phocein family
104	MYC	oncoprotein	45	0.350	391.024	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region
105	NEDD1	interactor	16	0.642	11.541	NRBF2 (PF08961, IPR015056): Nuclear receptor-binding factor 2, autophagy regulator eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A FliM (PF02154, IPR001689): Flagellar motor switch protein FliM WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Mto2_bdg (PF12808, IPR024545): Micro-tubular organiser Mto1 C-term Mto2-binding region ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
106	NFKB1	suppressor	16	0.333	226.407	Death (PF00531, IPR000488, SM00005): Death domain GHMP_kinases_C (PF08544, IPR013750): GHMP kinases C terminal RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
107	NFYA	interactor	9	0.444	76.688	CBFB_NFYA (PF02045, IPR001289): CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B MSP1_C (PF07462, IPR010901): Merozoite surface protein 1 (MSP1) C-terminus FixG_C (PF11614, IPR032879): IG-like fold at C-terminal of FixG, putative oxidoreductase DUF4237 (PF14021, IPR025331): Protein of unknown function (DUF4237)
108	NIPSNAP1	interactor	15	0.733	3.135	NIPSNAP (PF07978, IPR012577): NIPSNAP
109	NOS2	interactor	23	0.545	12.309	FAD_binding_1 (PF00667, IPR003097): FAD binding domain Flavodoxin_1 (PF00258, IPR008254): Flavodoxin NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain
110	NPM1	suppressor	49	0.395	196.723	Nucleoplasmin (PF03066): Nucleoplasmin/nucleophosmin domain SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
111	NSFL1C	interactor	9	0.528	10.103	SEP (PF08059, IPR012989, SM00553): SEP domain UBX (PF00789, IPR001012, SM00166): UBX domain UBA_4 (PF14555): UBA-like domain
112	NSMAF	interactor	9	0.861	0.395	Beach (PF02138, IPR000409, SM01026): Beige/BEACH domain GRAM (PF02893, IPR004182, SM00568): GRAM domain NABP (PF07990, IPR012940): Nucleic acid binding protein NABP WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain PH_BEACH (PF14844, IPR023362): PH domain associated with Beige/BEACH
113	NTRK1	oncoprotein	68	0.315	468.656	I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
114	NXF1	interactor	37	0.246	289.016	NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat
115	OBSL1	interactor	36	0.432	97.433	BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
116	PACRG	suppressor	15	0.657	7.070	ParcG (PF10274, IPR019399): Parkin co-regulated protein
117	PAN2	interactor	18	0.484	28.349	RNase_T (PF00929, IPR013520): Exonuclease UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase WD40_like (PF17005, IPR031544): WD40-like domain
118	PARK2	suppressor	30	0.384	105.063	IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
119	PCK1	interactor	10	0.489	2.326	PEPCK (PF00821, IPR008209): Phosphoenolpyruvate carboxykinase
120	PDK3	interactor	9	1.000	0	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 (PF10436, IPR018955): Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase
121	PEX14	protein found in more fusions	14	0.564	6.737	HemX (PF04375, IPR007470): HemX, putative uroporphyrinogen-III C-methyltransferase Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
122	PEX7	interactor	9	0.972	0.182	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
123	PLK4	interactor	5	1.000	0	ABC1 (PF03109, IPR004147): ABC1 family Pkinase (PF00069, IPR000719): Protein kinase domain POLO_box (PF00659, IPR000959): POLO box duplicated region DUF4520 (PF15016, IPR027865): Domain of unknown function (DUF4520)
124	POC1A	interactor	10	0.711	5.961	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
125	POC1B	interactor	3	0.667	0.242	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
126	PPP1CC	oncoprotein	18	0.614	10.004	Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
127	PPP2CA	suppressor	39	0.449	106.489	Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
128	PPP2CB	suppressor	25	0.630	27.025	Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
129	PPP2R2A	interactor	19	0.754	6.323	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
130	PPP2R2B	interactor	15	0.848	2.499	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
131	PPP2R2C	suppressor	13	0.833	3.273	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
132	PPP2R2D	interactor	16	0.850	3.397	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
133	PPP4C	interactor	20	0.642	81.337	Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
134	PRKCDBP	suppressor	2	1.000	0	A1_Propeptide (PF07966, IPR012848): A1 Propeptide PTRF_SDPR (PF15237, IPR026752): PTRF/SDPR family
135	PRPF4	interactor	22	0.667	14.940	PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_like (PF17005, IPR031544): WD40-like domain
136	PRPF40A	protein found in more fusions	15	0.593	6.067	FF (PF01846, IPR002713, SM00441): FF domain MCR_alpha (PF02249, IPR009047): Methyl-coenzyme M reductase alpha subunit, C-terminal domain Transformer (PF06495, IPR010519): Fruit fly transformer protein WW (PF00397, IPR001202, SM00456): WW domain YqzE (PF14038, IPR025622): YqzE-like protein SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6 SRRM_C (PF15230, IPR029360): Serine/arginine repetitive matrix protein C-terminus SOBP (PF15279, IPR026092): Sine oculis-binding protein IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
137	PSMA3	interactor	33	0.427	83.256	Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
138	PSMB8	interactor	6	1.000	0	Proteasome (PF00227, IPR001353): Proteasome subunit
139	PSMC2	protein found in more fusions	34	0.430	82.332	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
140	PSMC6	interactor	24	0.415	37.829	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) AAA_2 (PF07724, IPR013093): AAA domain (Cdc48 subfamily) TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain
141	PSMD2	oncoprotein	36	0.243	159.049	PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat THAP (PF05485, IPR006612, SM00980): THAP domain HEAT_2 (PF13646): HEAT repeats
142	PTPA	suppressor	12	0.727	15.123	PTPA (PF03095, IPR004327): Phosphotyrosyl phosphate activator (PTPA) protein
143	RAD21	oncoprotein	17	0.515	13.319	Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
144	REL	oncoprotein	10	0.244	104.871	RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
145	RFWD2	suppressor	14	0.821	1.553	Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein IncA (PF04156, IPR007285): IncA protein WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) WD40_like (PF17005, IPR031544): WD40-like domain
146	RFWD3	interactor	12	0.682	1.988	OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
147	RPS3	interactor	40	0.324	132.219	KH_2 (PF07650, IPR004044): KH domain Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain
148	RPS6KB2	interactor	26	0.397	37.274	Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
149	RUNX1	suppressor	6	0.200	42.406	Runt (PF00853, IPR013524): Runt domain RunxI (PF08504, IPR013711): Runx inhibition domain DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037)
150	SEC31B	interactor	9	0.917	0.508	SRA1 (PF07304, IPR009917): Steroid receptor RNA activator (SRA1) ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain Sec16_C (PF12931, IPR024298): Sec23-binding domain of Sec16
151	SF3B3	interactor	22	0.489	28.093	CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
152	SHC1	oncoprotein	22	0.414	36.617	PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) SH2 (PF00017, IPR000980, SM00252): SH2 domain
153	SIRT7	interactor	25	0.427	34.515	DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family
154	SMURF1	interactor	21	0.458	15.102	C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
155	SNW1	protein found in more fusions	47	0.375	201.781	SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain
156	SP1	protein found in more fusions	21	0.305	265.195	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
157	SSR1	interactor	11	0.764	1.561	TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
158	SSSCA1	interactor	7	0.533	2.268	Auto_anti-p27 (PF06677, IPR009563): Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27)
159	STAU1	protein found in more fusions	25	0.453	27.495	dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
160	STK24	interactor	19	0.712	14.004	DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241) Pkinase (PF00069, IPR000719): Protein kinase domain
161	STRN	oncoprotein	17	0.853	3.791	CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) Nucleoporin_N (PF08801, IPR014908): Nup133 N terminal like Striatin (PF08232, IPR013258): Striatin family WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
162	STRN3	interactor	17	0.824	5.599	Striatin (PF08232, IPR013258): Striatin family WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
163	TCF3	suppressor	4	0.333	21.639	CDC45 (PF02724, IPR003874): CDC45-like protein HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
164	TCP1	interactor	111	0.191	1645.220	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
165	TP53	suppressor	61	0.319	542.752	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
166	TRIM28	protein found in more fusions	39	0.373	98.338	ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
167	TSSK6	interactor	10	0.733	0.794	Pkinase (PF00069, IPR000719): Protein kinase domain
168	TTLL3	oncoprotein	7	1.000	0	TTL (PF03133, IPR004344): Tubulin-tyrosine ligase family
169	TUBA1B	interactor	21	0.367	47.553	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
170	TUBA1C	interactor	37	0.521	54.287	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
171	TUBA3E	interactor	6	0.867	0.458	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
172	TUBAL3	interactor	8	0.714	1.290	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
173	TUBB	interactor	50	0.309	234.190	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
174	TUBB2A	interactor	20	0.300	36.830	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
175	TUBB2B	interactor	20	0.511	21.153	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
176	TUBG1	protein found in more fusions	31	0.563	35.130	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
177	TXNL1	interactor	9	0.722	1.627	PITH (PF06201, IPR010400): PITH domain Thioredoxin (PF00085, IPR013766): Thioredoxin
178	TYK2	interactor	14	0.654	5.154	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
179	U2AF2	protein found in more fusions	32	0.488	52.432	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein
180	UBC	protein found in more fusions	54	0.331	308.702	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
181	VAV2	oncoprotein	7	0.619	2.337	PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain CotJB (PF12652, IPR024207): CotJB protein
182	VCAM1	interactor	31	0.477	35.937	C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain
183	VCP	protein found in more fusions	64	0.359	450.742	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
184	VHL	suppressor	26	0.557	57.013	Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): VHL beta domain VHL_C (PF17211): VHL box domain
185	VRK2	interactor	6	0.867	0.448	Pkinase (PF00069, IPR000719): Protein kinase domain VP_N-CPKC (PF11475, IPR021573): Virion protein N terminal domain
186	WDR76	interactor	8	0.821	0.228	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat SPATIAL (PF15256): SPATIAL
187	WDR83	interactor	11	0.836	2.345	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
188	WRAP53	oncoprotein	10	0.978	0.222	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
189	WRAP73	interactor	7	0.467	4.227	eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A IKI3 (PF04762, IPR006849): IKI3 family WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2555 (PF10742, IPR019678): Protein of unknown function (DUF2555) ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
190	WWOX	suppressor	14	0.473	12.329	adh_short (PF00106, IPR002198): short chain dehydrogenase WW (PF00397, IPR001202, SM00456): WW domain
191	XIAP	interactor	7	0.400	5.870	BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)

B a c k    t o    T o p ⇑

List of missing interactors (in fusions)

#	Name	Type	Domains (Pfam, InterPro, SMART): description	Fusion(s)
1	ACTA1	interactor	Actin (PF00022, IPR004000, SM00268): Actin	BG180662
2	ACTB	oncoprotein	Actin (PF00022, IPR004000, SM00268): Actin	BG180662
3	ACTL6A	interactor	Actin (PF00022, IPR004000, SM00268): Actin	BG180662
4	ACTR1B	interactor	Actin (PF00022, IPR004000, SM00268): Actin	BG180662
5	ACTR2	interactor	Actin (PF00022, IPR004000, SM00268): Actin	BG180662
6	AHSA1	interactor	Aha1_N (PF09229, IPR015310, SM01000): Activator of Hsp90 ATPase, N-terminal AHSA1 (PF08327, IPR013538): Activator of Hsp90 ATPase homolog 1-like protein	BG180662
7	ALKBH3	interactor	2OG-FeII_Oxy_2 (PF13532, IPR027450): 2OG-Fe(II) oxygenase superfamily	BG180662
8	AMBRA1	interactor	Acyl_CoA_thio (PF02551, IPR025652): Acyl-CoA thioesterase eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Spt20 (PF12090, IPR021950): Spt20 family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
9	ARMC6	interactor	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Mis14 (PF08641, IPR013950): Kinetochore protein Mis14 like Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain	BG180662
10	ATG16L1	interactor	ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2332 (PF10094, IPR011200): Uncharacterized protein conserved in bacteria (DUF2332) Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160	BG180662
11	ATP6V1B1	interactor	ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain DUF3533 (PF12051, IPR022703): Protein of unknown function (DUF3533)	BG180662
12	B9D1	interactor	Ribosomal_L40e (PF01020, IPR001975): Ribosomal L40e family	BG180662
13	BTRC	oncoprotein	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like	BG180662
14	BUB1B	oncoprotein	Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1 Mad3_BUB1_II (PF08171, IPR012572): Mad3/BUB1 homology region 2 Pkinase (PF00069, IPR000719): Protein kinase domain XhlA (PF10779, IPR019715): Haemolysin XhlA CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167	BG180662
15	BUB3	interactor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat	BG180662
16	C11orf54	interactor	DUF1907 (PF08925, IPR015021, SM01168): Domain of Unknown Function (DUF1907)	BG180662
17	CAMKMT	interactor	Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase	BG180662
18	CASP7	interactor	Peptidase_C14 (PF00656, IPR011600): Caspase domain PRIMA1 (PF16101): Proline-rich membrane anchor 1	BG180662
19	CCDC8	interactor	Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA	BG180662
20	CCNE1	oncoprotein	Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain	BG180662
21	CCT2	parental protein	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family	BG180662
22	CCT3	interactor	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family	BG180662
23	CCT4	interactor	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family	BG180662
24	CCT5	interactor	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family	BG180662
25	CCT6A	interactor	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family	BG180662
26	CCT6B	interactor	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family	BG180662
27	CCT7	interactor	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family	BG180662
28	CCT8	interactor	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family	BG180662
29	CDC20	oncoprotein	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
30	CDC5L	interactor	OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain	BG180662
31	CDK15	interactor	Pkinase (PF00069, IPR000719): Protein kinase domain ACT_5 (PF13710): ACT domain	BG180662
32	CDK2	suppressor	Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain	BG180662
33	CDK5	oncoprotein	Pkinase (PF00069, IPR000719): Protein kinase domain	BG180662
34	CDK7	oncoprotein	Pkinase (PF00069, IPR000719): Protein kinase domain	BG180662
35	CETN2	interactor	EF-hand_7 (PF13499, IPR011992): EF-hand domain pair	BG180662
36	COPS5	interactor	JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease	BG180662
37	CRY2	interactor	DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase	BG180662
38	CTTNBP2	interactor	Carmo_coat_C (PF08462, IPR013669): Carmovirus coat protein CortBP2 (PF09727, IPR019131): Cortactin-binding protein-2 Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour	BG180662
39	CUL1	suppressor	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain	BG180662
40	CUL3	interactor	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal	BG180662
41	CUL7	interactor	ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7	BG180662
42	CYB5B	interactor	Cyt-b5 (PF00173, IPR001199, SM01117): Cytochrome b5-like Heme/Steroid binding domain MIP (PF00230, IPR000425): Major intrinsic protein	BG180662
43	DCAF5	interactor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2634 (PF10934, IPR020288): Protein of unknown function (DUF2634) IMUP (PF15761, IPR026621): Immortalisation up-regulated protein	BG180662
44	DCAF7	interactor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat	BG180662
45	DDB2	suppressor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat	BG180662
46	DNAJA1	interactor	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain	BG180662
47	DNAJA4	interactor	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain	BG180662
48	EEF1D	interactor	EF1_GNE (PF00736, IPR014038, SM00888): EF-1 guanine nucleotide exchange domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region	BG180662
49	EEF2	interactor	EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II	BG180662
50	ELF1	parental protein	Ets (PF00178, IPR000418, SM00413): Ets-domain PAPA-1 (PF04795, IPR006880): PAPA-1-like conserved region Elf-1_N (PF12310, IPR022084): Transcription factor protein N terminal	BG180662
51	ENDOV	interactor	Endonuclease_5 (PF04493, IPR007581): Endonuclease V	BG180662
52	ERLIN2	interactor	Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family DUF4346 (PF14251, IPR025595): Domain of unknown function (DUF4346)	BG180662
53	ESR1	suppressor	Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal	BG180662
54	FAM86B2	interactor	Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase FAM86 (PF14904, IPR029426): Family of unknown function	BG180662
55	FBXO6	interactor	FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like	BG180662
56	FBXW4	oncoprotein	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat F-box-like (PF12937, IPR001810): F-box-like F-box_4 (PF15966, IPR001810): F-box	BG180662
57	FBXW8	interactor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like	BG180662
58	FCHSD2	interactor	Cortex-I_coil (PF09304, IPR015383): Cortexillin I, coiled coil DivIC (PF04977, IPR007060): Septum formation initiator FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain DUF4665 (PF15679, IPR031389): Domain of unknown function (DUF4665) Rit1_C (PF17184): Rit1 N-terminal domain	BG180662
59	FN1	oncoprotein	fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)	BG180662
60	FUS	suppressor	Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Limkain-b1 (PF11608, IPR024582): Limkain b1 FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head	BG180662
61	FYCO1	interactor	Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger HAP1_N (PF04849, IPR006933): HAP1 N-terminal conserved region RUN (PF02759, IPR004012, SM00593): RUN domain Sec8_exocyst (PF04048, IPR007191): Sec8 exocyst complex component specific domain Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Spectrin (PF00435, IPR002017): Spectrin repeat Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal TSC22 (PF01166, IPR000580): TSC-22/dip/bun family bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like GOLD_2 (PF13897, IPR009038): Golgi-dynamics membrane-trafficking DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) DUF4578 (PF15147, IPR028106): Domain of unknown function (DUF4578) HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1	BG180662
62	GAN	interactor	BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif	BG180662
63	GPR37	interactor	7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)	BG180662
64	GRB2	oncoprotein	SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)	BG180662
65	GSPT1	oncoprotein	GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region	BG180662
66	GSPT2	interactor	GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region	BG180662
67	GTF2I	interactor	GTF2I (PF02946, IPR004212): GTF2I-like repeat	BG180662
68	HDAC1	suppressor	FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain	BG180662
69	HDAC3	suppressor	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain	BG180662
70	HDAC5	interactor	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4	BG180662
71	HMGA1	oncoprotein	AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF2239 (PF09998, IPR018715): Uncharacterized protein conserved in bacteria (DUF2239)	BG180662
72	HOXC13	oncoprotein	Homeobox (PF00046, IPR001356, SM00389): Homeobox domain HoxA13_N (PF12284, IPR022067): Hox protein A13 N terminal	BG180662
73	HSP90AA1	oncoprotein	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein	BG180662
74	HSP90AB1	oncoprotein	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein	BG180662
75	HSP90B1	suppressor	CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region	BG180662
76	HSPA4	interactor	Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5	BG180662
77	HSPE1	interactor	Cpn10 (PF00166, IPR020818, SM00883): Chaperonin 10 Kd subunit	BG180662
78	HSPH1	oncoprotein	HSP70 (PF00012, IPR013126): Hsp70 protein SICA_alpha (PF12887, IPR024290): SICA extracellular alpha domain	BG180662
79	HUWE1	oncoprotein	BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)	BG180662
80	IGBP1	interactor	TAP42 (PF04177, IPR007304): TAP42-like family	BG180662
81	IKBKE	interactor	IncA (PF04156, IPR007285): IncA protein Pkinase (PF00069, IPR000719): Protein kinase domain SlyX (PF04102, IPR007236): SlyX zf-RING_9 (PF13901, IPR025258): Putative zinc-RING and/or ribbon	BG180662
82	ILK	suppressor	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies)	BG180662
83	IQGAP1	interactor	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF87 (PF01935, IPR002789): Domain of unknown function DUF87 IDEAL (PF08858, IPR014957, SM00914): IDEAL domain IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase RasGAP_C (PF03836, IPR000593): RasGAP C-terminus WW (PF00397, IPR001202, SM00456): WW domain	BG180662
84	IRAK1	interactor	Death (PF00531, IPR000488, SM00005): Death domain Pkinase (PF00069, IPR000719): Protein kinase domain	BG180662
85	ISG15	suppressor	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family	BG180662
86	ITGA4	interactor	FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha	BG180662
87	JAK3	oncoprotein	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain	BG180662
88	KIF21A	interactor	DUF1690 (PF07956, IPR012471): Protein of Unknown function (DUF1690) DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Strep_SA_rep (PF06696, IPR009578): Streptococcal surface antigen repeat TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding TSNAXIP1_N (PF15739, IPR032755): Translin-associated factor X-interacting N-terminus DUF4746 (PF15928, IPR031827): Domain of unknown function (DUF4746) HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1	BG180662
89	KPNA4	interactor	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat IBB (PF01749, IPR002652): Importin beta binding domain Arm_3 (PF16186, IPR032413): Atypical Arm repeat	BG180662
90	KRAS	oncoprotein	Ras (PF00071, IPR001806, SM00173): Ras family	BG180662
91	LFNG	oncoprotein	Fringe (PF02434, IPR003378): Fringe-like	BG180662
92	LGALS3BP	oncoprotein	BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain SRCR_2 (PF15494, IPR017448): Scavenger receptor cysteine-rich domain	BG180662
93	LRRK1	interactor	Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase Pkinase (PF00069, IPR000719): Protein kinase domain TniB (PF05621, IPR008868): Bacterial TniB protein Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat COR (PF16095, IPR032171): C-terminal of Roc, COR, domain	BG180662
94	MAPK10	suppressor	Pkinase (PF00069, IPR000719): Protein kinase domain	BG180662
95	MAPK8	oncoprotein	DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530) Pkinase (PF00069, IPR000719): Protein kinase domain	BG180662
96	MCM2	oncoprotein	AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain	BG180662
97	MEPCE	interactor	Bin3 (PF06859, IPR010675): Bicoid-interacting protein 3 (Bin3) Methyltransf_23 (PF13489): Methyltransferase domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 DLEU7 (PF15760, IPR031510): Leukemia-associated protein 7	BG180662
98	METTL18	interactor	Methyltransf_23 (PF13489): Methyltransferase domain	BG180662
99	METTL21B	interactor	Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase	BG180662
100	MKS1	interactor	B9-C2 (PF07162, IPR010796): Ciliary basal body-associated, B9 protein	BG180662
101	MLST8	interactor	Hira (PF07569, IPR011494): TUP1-like enhancer of split WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160	BG180662
102	MOB4	interactor	Mob1_phocein (PF03637, IPR005301): Mob1/phocein family	BG180662
103	MYC	oncoprotein	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region	BG180662
104	NEDD1	interactor	NRBF2 (PF08961, IPR015056): Nuclear receptor-binding factor 2, autophagy regulator eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A FliM (PF02154, IPR001689): Flagellar motor switch protein FliM WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Mto2_bdg (PF12808, IPR024545): Micro-tubular organiser Mto1 C-term Mto2-binding region ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
105	NIPSNAP1	interactor	NIPSNAP (PF07978, IPR012577): NIPSNAP	BG180662
106	NOS2	interactor	FAD_binding_1 (PF00667, IPR003097): FAD binding domain Flavodoxin_1 (PF00258, IPR008254): Flavodoxin NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain	BG180662
107	NPM1	suppressor	Nucleoplasmin (PF03066): Nucleoplasmin/nucleophosmin domain SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain	BG180662
108	NSFL1C	interactor	SEP (PF08059, IPR012989, SM00553): SEP domain UBX (PF00789, IPR001012, SM00166): UBX domain UBA_4 (PF14555): UBA-like domain	BG180662
109	NSMAF	interactor	Beach (PF02138, IPR000409, SM01026): Beige/BEACH domain GRAM (PF02893, IPR004182, SM00568): GRAM domain NABP (PF07990, IPR012940): Nucleic acid binding protein NABP WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain PH_BEACH (PF14844, IPR023362): PH domain associated with Beige/BEACH	BG180662
110	NTRK1	oncoprotein	I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain	BG180662
111	NXF1	interactor	NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat	BG180662
112	OBSL1	interactor	BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain	BG180662
113	PACRG	suppressor	ParcG (PF10274, IPR019399): Parkin co-regulated protein	BG180662
114	PAN2	interactor	RNase_T (PF00929, IPR013520): Exonuclease UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase WD40_like (PF17005, IPR031544): WD40-like domain	BG180662
115	PARK2	suppressor	IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family	BG180662
116	PCK1	interactor	PEPCK (PF00821, IPR008209): Phosphoenolpyruvate carboxykinase	BG180662
117	PDK3	interactor	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 (PF10436, IPR018955): Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase	BG180662
118	PEX14	interactor	HemX (PF04375, IPR007470): HemX, putative uroporphyrinogen-III C-methyltransferase Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation	BG180662
119	PEX7	interactor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat	BG180662
120	PLK4	interactor	ABC1 (PF03109, IPR004147): ABC1 family Pkinase (PF00069, IPR000719): Protein kinase domain POLO_box (PF00659, IPR000959): POLO box duplicated region DUF4520 (PF15016, IPR027865): Domain of unknown function (DUF4520)	BG180662
121	POC1A	interactor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat	BG180662
122	POC1B	interactor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
123	PPP1CC	oncoprotein	Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain	BG180662
124	PPP2CA	suppressor	Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain	BG180662
125	PPP2CB	suppressor	Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain	BG180662
126	PPP2R2A	interactor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
127	PPP2R2B	interactor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
128	PPP2R2C	suppressor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
129	PPP2R2D	interactor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
130	PPP4C	interactor	Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain	BG180662
131	PRKCDBP	suppressor	A1_Propeptide (PF07966, IPR012848): A1 Propeptide PTRF_SDPR (PF15237, IPR026752): PTRF/SDPR family	BG180662
132	PRPF4	interactor	PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_like (PF17005, IPR031544): WD40-like domain	BG180662
133	PRPF40A	interactor	FF (PF01846, IPR002713, SM00441): FF domain MCR_alpha (PF02249, IPR009047): Methyl-coenzyme M reductase alpha subunit, C-terminal domain Transformer (PF06495, IPR010519): Fruit fly transformer protein WW (PF00397, IPR001202, SM00456): WW domain YqzE (PF14038, IPR025622): YqzE-like protein SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6 SRRM_C (PF15230, IPR029360): Serine/arginine repetitive matrix protein C-terminus SOBP (PF15279, IPR026092): Sine oculis-binding protein IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal	BG180662
134	PSMA3	interactor	Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature	BG180662
135	PSMB8	interactor	Proteasome (PF00227, IPR001353): Proteasome subunit	BG180662
136	PSMC2	interactor	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)	BG180662
137	PSMC6	interactor	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) AAA_2 (PF07724, IPR013093): AAA domain (Cdc48 subfamily) TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain	BG180662
138	PSMD2	oncoprotein	PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat THAP (PF05485, IPR006612, SM00980): THAP domain HEAT_2 (PF13646): HEAT repeats	BG180662
139	PTPA	suppressor	PTPA (PF03095, IPR004327): Phosphotyrosyl phosphate activator (PTPA) protein	BG180662
140	RAD21	oncoprotein	Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box	BG180662
141	REL	oncoprotein	RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain	BG180662
142	RFWD2	suppressor	Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein IncA (PF04156, IPR007285): IncA protein WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) WD40_like (PF17005, IPR031544): WD40-like domain	BG180662
143	RFWD3	interactor	OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
144	RPS3	interactor	KH_2 (PF07650, IPR004044): KH domain Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain	BG180662
145	RPS6KB2	interactor	Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain	BG180662
146	RUNX1	suppressor	Runt (PF00853, IPR013524): Runt domain RunxI (PF08504, IPR013711): Runx inhibition domain DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037)	BG180662
147	SEC31B	interactor	SRA1 (PF07304, IPR009917): Steroid receptor RNA activator (SRA1) ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain Sec16_C (PF12931, IPR024298): Sec23-binding domain of Sec16	BG180662
148	SF3B3	interactor	CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term	BG180662
149	SHC1	oncoprotein	PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) SH2 (PF00017, IPR000980, SM00252): SH2 domain	BG180662
150	SIRT7	interactor	DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family	BG180662
151	SMURF1	interactor	C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)	BG180662
152	SNW1	interactor	SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain	BG180662
153	SP1	interactor	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1	BG180662
154	SSR1	interactor	TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit	BG180662
155	SSSCA1	interactor	Auto_anti-p27 (PF06677, IPR009563): Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27)	BG180662
156	STAU1	interactor	dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain	BG180662
157	STK24	interactor	DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241) Pkinase (PF00069, IPR000719): Protein kinase domain	BG180662
158	STRN	oncoprotein	CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) Nucleoporin_N (PF08801, IPR014908): Nup133 N terminal like Striatin (PF08232, IPR013258): Striatin family WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
159	STRN3	interactor	Striatin (PF08232, IPR013258): Striatin family WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
160	TCP1	interactor	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family	BG180662
161	TP53	suppressor	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif	BG180662
162	TRIM28	interactor	ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2	BG180662
163	TSSK6	interactor	Pkinase (PF00069, IPR000719): Protein kinase domain	BG180662
164	TTLL3	oncoprotein	TTL (PF03133, IPR004344): Tubulin-tyrosine ligase family	BG180662
165	TUBA1B	interactor	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain	BG180662
166	TUBA1C	interactor	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain	BG180662
167	TUBA3E	interactor	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain	BG180662
168	TUBAL3	interactor	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain	BG180662
169	TUBB	interactor	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain	BG180662
170	TUBB2A	interactor	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain	BG180662
171	TUBB2B	interactor	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain	BG180662
172	TUBG1	interactor	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain	BG180662
173	TXNL1	interactor	PITH (PF06201, IPR010400): PITH domain Thioredoxin (PF00085, IPR013766): Thioredoxin	BG180662
174	TYK2	interactor	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase	BG180662
175	U2AF2	interactor	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein	BG180662
176	UBC	interactor	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family	BG180662
177	VAV2	oncoprotein	PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain CotJB (PF12652, IPR024207): CotJB protein	BG180662
178	VCAM1	interactor	C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain	BG180662
179	VCP	interactor	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)	BG180662
180	VHL	suppressor	Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): VHL beta domain VHL_C (PF17211): VHL box domain	BG180662
181	VRK2	interactor	Pkinase (PF00069, IPR000719): Protein kinase domain VP_N-CPKC (PF11475, IPR021573): Virion protein N terminal domain	BG180662
182	WDR76	interactor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat SPATIAL (PF15256): SPATIAL	BG180662
183	WDR83	interactor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
184	WRAP53	oncoprotein	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
185	WRAP73	interactor	eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A IKI3 (PF04762, IPR006849): IKI3 family WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2555 (PF10742, IPR019678): Protein of unknown function (DUF2555) ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain	BG180662
186	WWOX	suppressor	adh_short (PF00106, IPR002198): short chain dehydrogenase WW (PF00397, IPR001202, SM00456): WW domain	BG180662
187	XIAP	interactor	BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)	BG180662

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