1 |
EIF2AK2 | parental protein | 89 | 0.112 | 4302.167 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Pkinase (PF00069, IPR000719): Protein kinase domain |
2 |
ATP6V1F | interactor | 2 | 1.000 | 0 | ATP-synt_F (PF01990, IPR008218): ATP synthase (F/14-kDa) subunit |
3 |
CAND1 | interactor | 39 | 0.300 | 247.847 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
4 |
CCDC124 | interactor | 6 | 0.733 | 1.372 | DUF1014 (PF06244, IPR010422): Protein of unknown function (DUF1014) Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR DUF4569 (PF15133, IPR027869): Domain of unknown function (DUF4569) |
5 |
CCNA2 | oncoprotein | 6 | 0.400 | 4.667 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain Cyclin_N2 (PF16500, IPR032447): N-terminal region of cyclin_N |
6 |
CDC37 | protein found in more fusions | 12 | 0.455 | 18.505 | CDC37_C (PF08564, IPR013873, SM01069): Cdc37 C terminal domain CDC37_M (PF08565, IPR013874, SM01070): Cdc37 Hsp90 binding domain CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding Rho_Binding (PF08912, IPR015008): Rho Binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding |
7 |
CDCA5 | interactor | 3 | 1.000 | 0 | Sororin (PF09666, IPR018605): Sororin protein |
8 |
CDK3 | interactor | 3 | 0.667 | 0.667 | Pkinase (PF00069, IPR000719): Protein kinase domain |
9 |
CHMP4B | interactor | 4 | 0.667 | 0.333 | Snf7 (PF03357, IPR005024): Snf7 |
10 |
CHUK | suppressor | 12 | 0.582 | 8.895 | Pkinase (PF00069, IPR000719): Protein kinase domain IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain |
11 |
CUL3 | protein found in more fusions | 36 | 0.296 | 209.480 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
12 |
CYP1A1 | oncoprotein | 3 | 0.667 | 0.500 | p450 (PF00067, IPR001128): Cytochrome P450 |
13 |
DBNL | interactor | 2 | 1.000 | 0 | RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 Rrn6 (PF10214, IPR019350): RNA polymerase I-specific transcription-initiation factor Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein SH3_9 (PF14604, IPR001452): Variant SH3 domain |
14 |
DHX30 | interactor | 12 | 0.697 | 7.096 | Bombolitin (PF08096, IPR012534): Bombolitin family DEAD (PF00270, IPR011545): DEAD/DEAH box helicase dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Dicer_dimer (PF03368, IPR005034): Dicer dimerisation domain OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
15 |
DHX58 | interactor | 7 | 0.429 | 5.158 | ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain RIG-I_C-RD (PF11648, IPR021673): C-terminal domain of RIG-I Folliculin (PF11704, IPR021713): Vesicle coat protein involved in Golgi to plasma membrane transport AAA_19 (PF13245): Part of AAA domain |
16 |
DHX9 | oncoprotein | 19 | 0.520 | 37.569 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold T2SSE (PF00437, IPR001482): Type II/IV secretion system protein HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
17 |
DICER1 | oncoprotein | 13 | 0.515 | 13.708 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Dicer_dimer (PF03368, IPR005034): Dicer dimerisation domain PAZ (PF02170, IPR003100, SM00949): PAZ domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Ribonuclease_3 (PF00636, IPR000999, SM00535): Ribonuclease III domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611) |
18 |
DNAJC3 | interactor | 1 | 0 | 0 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_21 (PF09976, IPR018704): Tetratricopeptide repeat-like domain Ndufs5 (PF10200, IPR019342): NADH:ubiquinone oxidoreductase, NDUFS5-15kDa TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat DUF4363 (PF14276, IPR025373): Domain of unknown function (DUF4363) TPR_19 (PF14559): Tetratricopeptide repeat |
19 |
EBNA1BP2 | interactor | 17 | 0.551 | 22.546 | Ebp2 (PF05890, IPR008610): Eukaryotic rRNA processing protein EBP2 |
20 |
EDC4 | interactor | 6 | 0.733 | 1.256 | DUF445 (PF04286, IPR007383): Protein of unknown function (DUF445) SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein DUF2756 (PF10956, IPR020158): Protein of unknown function (DUF2756) DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446) Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein |
21 |
EGFR | oncoprotein | 14 | 0.385 | 28.608 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
22 |
EIF2A | interactor | 5 | 0.600 | 2.556 | Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A |
23 |
EIF2S1 | interactor | 6 | 0.733 | 0.815 | EIF_2_alpha (PF07541, IPR011488): Eukaryotic translation initiation factor 2 alpha subunit S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain |
24 |
EIF6 | interactor | 14 | 0.473 | 26.386 | eIF-6 (PF01912, IPR002769, SM00654): eIF-6 family |
25 |
ELAVL1 | oncoprotein | 25 | 0.246 | 148.813 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
26 |
ELMSAN1 | interactor | 3 | 0.667 | 0.500 | ELM2 (PF01448, IPR000949): ELM2 domain FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
27 |
FANCC | oncoprotein | 4 | 0.667 | 0.622 | Fanconi_C (PF02106, IPR000686): Fanconi anaemia group C protein |
28 |
FARSA | interactor | 6 | 0.667 | 2.192 | tRNA-synt_2d (PF01409, IPR002319): tRNA synthetases class II core domain (F) MarR_2 (PF12802): MarR family |
29 |
FARSB | interactor | 5 | 0.800 | 0.952 | B3_4 (PF03483, IPR005146, SM00873): B3/4 domain B5 (PF03484, IPR005147, SM00874): tRNA synthetase B5 domain |
30 |
FTSJ3 | interactor | 11 | 0.818 | 2.084 | DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) FtsJ (PF01728, IPR002877): FtsJ-like methyltransferase M16C_assoc (PF08367, IPR013578): Peptidase M16C associated Orthopox_F8 (PF05886, IPR008726): Orthopoxvirus F8 protein Spb1_C (PF07780, IPR012920): Spb1 C-terminal domain DUF3381 (PF11861, IPR024576): Domain of unknown function (DUF3381) RRP14 (PF15459, IPR029188): 60S ribosome biogenesis protein Rrp14 |
31 |
GLTSCR2 | oncoprotein | 7 | 0.667 | 2.323 | Nop53 (PF07767, IPR011687): Nop53 (60S ribosomal biogenesis) |
32 |
GNL3 | interactor | 14 | 0.626 | 11.591 | GN3L_Grn1 (PF08701, IPR014813): GNL3L/Grn1 putative GTPase GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family FAM176 (PF14851): FAM176 family |
33 |
GTPBP4 | suppressor | 17 | 0.515 | 30.845 | DUF258 (PF03193, IPR004881): Protein of unknown function, DUF258 MRC1 (PF09444, IPR018564): MRC1-like domain NOG1 (PF06858, IPR010674): Nucleolar GTP-binding protein 1 (NOG1) NOGCT (PF08155, IPR012973): NOGCT (NUC087) domain Lip_prot_lig_C (PF10437, IPR019491): Bacterial lipoate protein ligase C-terminus AAA_16 (PF13191): AAA ATPase domain |
34 |
HDGF | interactor | 16 | 0.408 | 27.431 | PWWP (PF00855, IPR000313, SM00293): PWWP domain |
35 |
HECW2 | interactor | 4 | 1.000 | 0 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57 RFXA_RFXANK_bdg (PF15289, IPR029316): Regulatory factor X-associated C-terminal binding domain HECW_N (PF16562, IPR032348): N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 |
36 |
HIST1H1C | oncoprotein | 9 | 0.667 | 2.870 | Amelin (PF05111, IPR007798, SM00817): Ameloblastin precursor (Amelin) Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family DUF4349 (PF14257, IPR025645): Domain of unknown function (DUF4349) |
37 |
HIST2H2AC | interactor | 3 | 1.000 | 0 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A |
38 |
HNRNPC | protein found in more fusions | 14 | 0.705 | 8.382 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SURF2 (PF05477, IPR008833): Surfeit locus protein 2 (SURF2) |
39 |
HNRNPCL1 | interactor | 4 | 1.000 | 0 | FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) XhlA (PF10779, IPR019715): Haemolysin XhlA |
40 |
HSP90AA1 | oncoprotein | 23 | 0.290 | 110.854 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
41 |
IFI16 | suppressor | 14 | 0.440 | 19.881 | HIN (PF02760, IPR004021): HIN-200/IF120x domain PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein |
42 |
IFRD1 | interactor | 3 | 1.000 | 0 | IFRD (PF05004, IPR007701): Interferon-related developmental regulator (IFRD) IFRD_C (PF04836, IPR006921): Interferon-related protein conserved region |
43 |
IGF2BP2 | interactor | 6 | 0.867 | 0.411 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_1 (PF00013, IPR004088, SM00322): KH domain KH_4 (PF13083): KH domain |
44 |
IGF2BP3 | interactor | 12 | 0.712 | 6.082 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_1 (PF00013, IPR004088, SM00322): KH domain KH_4 (PF13083): KH domain |
45 |
IKBKB | protein found in more fusions | 13 | 0.470 | 22.857 | FliT (PF05400, IPR008622): Flagellar protein FliT Glyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain Pkinase (PF00069, IPR000719): Protein kinase domain SlyX (PF04102, IPR007236): SlyX ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain |
46 |
IL7R | interactor | 11 | 0.436 | 10.029 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain |
47 |
ILF2 | interactor | 24 | 0.449 | 64.367 | DZF (PF07528, IPR006561, SM00572): DZF domain |
48 |
ILF3 | oncoprotein | 17 | 0.559 | 29.065 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif DZF (PF07528, IPR006561, SM00572): DZF domain |
49 |
ISG15 | suppressor | 5 | 0.700 | 0.872 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
50 |
JAK1 | oncoprotein | 10 | 0.639 | 5.875 | FERM_M (PF00373, IPR019748): FERM central domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain |
51 |
KCTD17 | interactor | 5 | 0.833 | 0.167 | BTB_2 (PF02214, IPR003131): BTB/POZ domain SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) |
52 |
LYAR | interactor | 12 | 0.667 | 5.215 | DEK_C (PF08766, IPR014876): DEK C terminal domain zf-LYAR (PF08790, IPR014898): LYAR-type C2HC zinc finger DUF3499 (PF12005, IPR021888): Protein of unknown function (DUF3499) U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal |
53 |
MACROD1 | oncoprotein | 3 | 0.667 | 0.667 | DUF1108 (PF06531, IPR009494): Protein of unknown function (DUF1108) DUF1502 (PF07397, IPR010871): Repeat of unknown function (DUF1502) Macro (PF01661, IPR002589, SM00506): Macro domain |
54 |
MAP3K5 | protein found in more fusions | 7 | 0.800 | 1.286 | Pkinase (PF00069, IPR000719): Protein kinase domain DUF4071 (PF13281, IPR025136): Domain of unknown function (DUF4071) |
55 |
MAP3K7 | oncoprotein | 13 | 0.530 | 16.952 | Mnd1 (PF03962, IPR005647): Mnd1 family Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
56 |
MAVS | interactor | 8 | 0.714 | 4.233 | Ice_nucleation (PF00818, IPR000258): Ice nucleation protein repeat CARD_2 (PF16739, IPR031964): Caspase recruitment domain |
57 |
MCM2 | oncoprotein | 22 | 0.348 | 88.635 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
58 |
METAP2 | oncoprotein | 2 | 1.000 | 0 | Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24 SRP72 (PF08492, IPR013699): SRP72 RNA-binding domain TSGP1 (PF07771, IPR011694): Tick salivary peptide group 1 |
59 |
MOV10 | interactor | 22 | 0.398 | 78.602 | AAA_12 (PF13087): AAA domain AAA_30 (PF13604): AAA domain |
60 |
NOC3L | interactor | 9 | 0.583 | 4.969 | CBF (PF03914, IPR005612, SM00521): CBF/Mak21 family Cytochrom_B562 (PF07361, IPR009155): Cytochrome b562 DsrD (PF08679, IPR014793): Dissimilatory sulfite reductase D (DsrD) GAGA_bind (PF06217, IPR010409): GAGA binding protein-like family NOC3p (PF07540, IPR011501): Nucleolar complex-associated protein Scm3 (PF10384, IPR018465): Centromere protein Scm3 |
61 |
NOP2 | interactor | 16 | 0.650 | 11.395 | BSP_II (PF05432, IPR008412): Bone sialoprotein II (BSP-II) Methyltr_RsmB-F (PF01189, IPR001678): 16S rRNA methyltransferase RsmB/F P120R (PF08062, IPR012586): P120R (NUC006) repeat Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein DUF2477 (PF10631, IPR018904): Protein of unknown function (DUF2477) FAM176 (PF14851): FAM176 family Methyltr_RsmF_N (PF17125, IPR031341): N-terminal domain of 16S rRNA methyltransferase RsmF |
62 |
NPM1 | oncoprotein | 31 | 0.313 | 162.997 | Nucleoplasmin (PF03066): Nucleoplasmin SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain |
63 |
NTRK1 | oncoprotein | 49 | 0.215 | 582.608 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
64 |
PABPC4 | interactor | 10 | 0.756 | 2.543 | ApbA_C (PF08546, IPR013752): Ketopantoate reductase PanE/ApbA C terminal RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain HHV-5_US34A (PF17087, IPR031384): Herpesvirus US34A protein family |
65 |
PDGFRB | oncoprotein | 6 | 1.000 | 0 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase V-set (PF07686, IPR013106): Immunoglobulin V-set domain C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain Ig_3 (PF13927): Immunoglobulin domain TonB_N (PF16031): TonB N-terminal region |
66 |
PPP1CA | oncoprotein | 9 | 0.500 | 7.702 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
67 |
PPP1CC | oncoprotein | 10 | 0.444 | 11.725 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
68 |
PPP2R5A | interactor | 1 | 0 | 0 | B56 (PF01603, IPR002554): Protein phosphatase 2A regulatory B subunit (B56 family) |
69 |
PRKRA | interactor | 15 | 0.495 | 20.738 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain |
70 |
PRKRIP1 | interactor | 2 | 1.000 | 0 | DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168) |
71 |
PTGES3 | interactor | 5 | 0.833 | 0.333 | CS (PF04969, IPR007052): CS domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
72 |
PURA | interactor | 5 | 0.700 | 0.545 | PurA (PF04845, IPR006628, SM00712): PurA ssDNA and RNA-binding protein DUF3276 (PF11680, IPR021694): Protein of unknown function (DUF3276) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
73 |
RPL10 | oncoprotein | 23 | 0.518 | 44.616 | Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e |
74 |
SCARB2 | interactor | 2 | 1.000 | 0 | CD36 (PF01130, IPR002159): CD36 family |
75 |
SSB | interactor | 9 | 0.472 | 10.674 | HMA (PF00403, IPR006121): Heavy-metal-associated domain La (PF05383, IPR006630, SM00715): La domain Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family Ribosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 (PF08777, IPR014886): RNA binding motif |
76 |
STAT1 | suppressor | 11 | 0.400 | 16.719 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain STAT1_TAZ2bind (PF12162, IPR022752): STAT1 TAZ2 binding domain |
77 |
STAT3 | oncoprotein | 13 | 0.439 | 17.502 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain |
78 |
STAU1 | protein found in more fusions | 25 | 0.453 | 64.391 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain |
79 |
STAU2 | interactor | 8 | 0.464 | 7.075 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif LPP20 (PF02169, IPR024952): LPP20 lipoprotein Staufen_C (PF16482, IPR032478): Staufen C-terminal domain |
80 |
TARBP2 | interactor | 9 | 0.571 | 4.891 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain |
81 |
TOLLIP | interactor | 5 | 0.500 | 1.317 | C2 (PF00168, IPR000008, SM00239): C2 domain CUE (PF02845, IPR003892, SM00546): CUE domain |
82 |
TOP1 | oncoprotein | 15 | 0.495 | 22.952 | DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Topoisom_I (PF01028, IPR013500): Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N (PF02919, IPR008336): Eukaryotic DNA topoisomerase I, DNA binding fragment MCM_bind (PF09739, IPR019140): Mini-chromosome maintenance replisome factor Sox_N (PF12444, IPR022151): Sox developmental protein N terminal Topo_C_assoc (PF14370, IPR025834): C-terminal topoisomerase domain DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) TonB_N (PF16031): TonB N-terminal region |
83 |
TP53 | oncoprotein | 21 | 0.242 | 94.529 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
84 |
TRAF2 | interactor | 12 | 0.491 | 18.150 | MATH (PF00917, IPR002083, SM00061): MATH domain Sina (PF03145, IPR018121): Seven in absentia protein family SlyX (PF04102, IPR007236): SlyX zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger) |
85 |
TRAF5 | interactor | 8 | 0.762 | 2.383 | Sina (PF03145, IPR018121): Seven in absentia protein family zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain HMMR_N (PF15905, IPR031787): Hyaluronan mediated motility receptor N-terminal Spc29 (PF17082, IPR031392): Spindle Pole Component 29 |
86 |
TRAF6 | protein found in more fusions | 13 | 0.439 | 22.060 | SlyX (PF04102, IPR007236): SlyX zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
87 |
TYK2 | interactor | 6 | 0.600 | 1.222 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
88 |
XRN2 | interactor | 10 | 0.489 | 13.111 | XRN_N (PF03159, IPR004859): XRN 5'-3' exonuclease N-terminus |
89 |
ZNF346 | interactor | 8 | 0.536 | 6.067 | zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger Vps39_2 (PF10367, IPR019453): Vacuolar sorting protein 39 domain 2 zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-met (PF12874): Zinc-finger of C2H2 type |