1 |
EEF1D | parental protein | 104 | 0.113 | 5792.909 | EF1_GNE (PF00736, IPR014038, SM00888): EF-1 guanine nucleotide exchange domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region |
2 |
ABTB1 | interactor | 2 | 1.000 | 0 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) |
3 |
ACLY | interactor | 12 | 0.515 | 8.435 | ATP-grasp_2 (PF08442, IPR013650): ATP-grasp domain Citrate_synt (PF00285, IPR002020): Citrate synthase, C-terminal domain CoA_binding (PF02629, IPR003781, SM00881): CoA binding domain Ligase_CoA (PF00549, IPR005811): CoA-ligase Citrate_bind (PF16114, IPR032263): ATP citrate lyase citrate-binding |
4 |
ADRB2 | interactor | 10 | 0.639 | 2.833 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) |
5 |
AHNAK | suppressor | 15 | 0.451 | 22.777 | DUF945 (PF06097, IPR010352): Bacterial protein of unknown function (DUF945) ELFV_dehydrog_N (PF02812, IPR006097): Glu/Leu/Phe/Val dehydrogenase, dimerisation domain T2SSN (PF01203, IPR022792): Type II secretion system (T2SS), protein N PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) TT_ORF2a (PF08197, IPR013267): pORF2a truncated protein DUF2993 (PF11209, IPR021373): Protein of unknown function (DUF2993) DUF4097 (PF13349, IPR025164): Putative adhesin Ntox37 (PF15535, IPR029108): Bacterial toxin 37 |
6 |
AKAP8 | interactor | 7 | 0.476 | 5.950 | AKAP95 (PF04988, IPR007071): A-kinase anchoring protein 95 (AKAP95) Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein |
7 |
ANLN | oncoprotein | 5 | 0.700 | 2.067 | Anillin (PF08174, IPR012966): Cell division protein anillin PH (PF00169, IPR001849, SM00233): PH domain Anillin_N (PF16018, IPR031970): Anillin N-terminus |
8 |
APC | suppressor | 7 | 0.400 | 7.150 | APC_15aa (PF05972, IPR009240): APC 15 residue motif APC_basic (PF05956, IPR009234): APC basic domain APC_r (PF05923): APC repeat Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) EB1_binding (PF05937, IPR009232): EB-1 Binding Domain FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) SAMP (PF05924, IPR009224): SAMP Motif Suppressor_APC (PF11414, IPR026831): Adenomatous polyposis coli tumour suppressor protein AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term SAS4 (PF15460, IPR029184): Something about silencing, SAS, complex subunit 4 Arm_APC_u3 (PF16629): Armadillo-associated region on APC APC_u5 (PF16630): Unstructured region on APC between 1st and 2nd catenin-bdg motifs APC_u9 (PF16633): Unstructured region on APC between 1st two creatine-rich regions APC_u13 (PF16634): Unstructured region on APC between APC_crr and SAMP APC_u14 (PF16635): Unstructured region on APC between SAMP and APC_crr APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6 APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain |
9 |
APP | protein found in more fusions | 25 | 0.250 | 123.801 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
10 |
ARHGAP21 | interactor | 5 | 0.800 | 1.333 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain MAJIN (PF15077, IPR027816): Membrane-anchored junction protein PH_9 (PF15410): Pleckstrin homology domain |
11 |
ASCC2 | interactor | 3 | 1.000 | 0 | CUE (PF02845, IPR003892, SM00546): CUE domain BLOC1S3 (PF15753, IPR017245): Biogenesis of lysosome-related organelles complex 1 subunit 3 |
12 |
ATG7 | interactor | 4 | 0.667 | 0.451 | ThiF (PF00899, IPR000594): ThiF family ATG7_N (PF16420, IPR032197): Ubiquitin-like modifier-activating enzyme ATG7 N-terminus |
13 |
BAG6 | interactor | 7 | 0.400 | 3.594 | DUF1179 (PF06678, IPR009564): Protein of unknown function (DUF1179) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family DUF2939 (PF11159, IPR021330): Protein of unknown function (DUF2939) DUF3538 (PF12057, IPR021925): Domain of unknown function (DUF3538) PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
14 |
CAMSAP2 | interactor | 2 | 1.000 | 0 | Bundlin (PF05307, IPR007971): Bundlin IncA (PF04156, IPR007285): IncA protein Presenilin (PF01080, IPR001108): Presenilin CAMSAP_CKK (PF08683, IPR014797, SM01051): Microtubule-binding calmodulin-regulated spectrin-associated CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain FAM60A (PF15396, IPR026065): Protein Family FAM60A CAMSAP_CC1 (PF17095, IPR031372): Spectrin-binding region of Ca2+-Calmodulin |
15 |
CCT2 | interactor | 18 | 0.464 | 20.390 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
16 |
CCT6A | interactor | 15 | 0.457 | 14.368 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
17 |
CD48 | interactor | 2 | 1.000 | 0 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain |
18 |
CD81 | interactor | 11 | 0.667 | 3.983 | Tetraspannin (PF00335, IPR018499): Tetraspanin family |
19 |
CDK2 | suppressor | 28 | 0.291 | 111.256 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
20 |
CRMP1 | interactor | 6 | 0.800 | 1.333 | Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family Amidohydro_3 (PF07969, IPR013108): Amidohydrolase family |
21 |
CSNK2A1 | oncoprotein | 22 | 0.333 | 82.382 | Pkinase (PF00069, IPR000719): Protein kinase domain |
22 |
CUL1 | suppressor | 24 | 0.462 | 43.901 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
23 |
CUL2 | suppressor | 17 | 0.500 | 22.188 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
24 |
CUL5 | suppressor | 16 | 0.592 | 15.038 | Cullin (PF00888, IPR001373, SM00182): Cullin family GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
25 |
CUL7 | protein found in more fusions | 32 | 0.256 | 125.507 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
26 |
DDX46 | interactor | 7 | 0.667 | 3.036 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) CdAMP_rec (PF06153, IPR010375): Cyclic-di-AMP receptor DDRGK (PF09756, IPR019153, SM01128): DDRGK domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term FAM176 (PF14851): FAM176 family |
27 |
ECH1 | interactor | 6 | 0.600 | 2.209 | ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase |
28 |
EED | suppressor | 21 | 0.311 | 50.437 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
29 |
EEF1A1 | suppressor | 31 | 0.432 | 91.199 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
30 |
EEF1A2 | oncoprotein | 13 | 0.436 | 19.571 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
31 |
EEF1B2 | interactor | 30 | 0.357 | 98.509 | EF1_GNE (PF00736, IPR014038, SM00888): EF-1 guanine nucleotide exchange domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region GST_C_6 (PF17171): Glutathione S-transferase, C-terminal domain |
32 |
EEF1G | protein found in more fusions | 29 | 0.307 | 139.085 | EF1G (PF00647, IPR001662): Elongation factor 1 gamma, conserved domain GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein |
33 |
ELF3 | oncoprotein | 3 | 1.000 | 0 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain |
34 |
EPRS | interactor | 15 | 0.324 | 20.130 | GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain ProRS-C_1 (PF09180, IPR016061, SM00946): Prolyl-tRNA synthetase, C-terminal tRNA-synt_1c (PF00749, IPR020058): tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C (PF03950, IPR020059): tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain |
35 |
ERP27 | interactor | 1 | 0 | 0 | Thioredoxin_6 (PF13848): Thioredoxin-like domain |
36 |
FBXO6 | interactor | 19 | 0.386 | 27.475 | FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like |
37 |
FLNC | interactor | 9 | 0.639 | 4.319 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Filamin (PF00630, IPR017868): Filamin/ABP280 repeat PapC_N (PF13954, IPR025885): PapC N-terminal domain |
38 |
FN1 | oncoprotein | 31 | 0.277 | 113.473 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
39 |
FOS | oncoprotein | 9 | 0.536 | 6.119 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
40 |
FOSL2 | oncoprotein | 4 | 0.667 | 1.286 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
41 |
FOXB1 | interactor | 4 | 0.667 | 0.800 | Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
42 |
FOXG1 | oncoprotein | 4 | 0.667 | 1.167 | SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region SPX (PF03105, IPR004331): SPX domain DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
43 |
FOXI2 | interactor | 2 | 1.000 | 0 | Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
44 |
FOXK1 | interactor | 5 | 0.600 | 3.167 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator FHA (PF00498, IPR000253, SM00240): FHA domain Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
45 |
FOXL1 | oncoprotein | 2 | 1.000 | 0 | Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
46 |
FRA10AC1 | interactor | 1 | 0 | 0 | SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region Fra10Ac1 (PF09725, IPR019129): Folate-sensitive fragile site protein Fra10Ac1 UBA2_C (PF16195, IPR032426): SUMO-activating enzyme subunit 2 C-terminus |
47 |
GARS | interactor | 8 | 0.536 | 2.650 | HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain |
48 |
GLI1 | suppressor | 2 | 1.000 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain |
49 |
GRB2 | oncoprotein | 14 | 0.615 | 7.809 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093) |
50 |
GTF2F1 | interactor | 7 | 0.619 | 3.375 | TFIIF_alpha (PF05793, IPR008851): Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) |
51 |
HCFC1 | protein found in more fusions | 7 | 0.667 | 2.460 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif zf-tcix (PF14952, IPR029269): Putative treble-clef, zinc-finger, Zn-binding |
52 |
HECW2 | interactor | 6 | 0.600 | 3.067 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57 RFXA_RFXANK_bdg (PF15289, IPR029316): Regulatory factor X-associated C-terminal binding domain HECW_N (PF16562, IPR032348): N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 |
53 |
HEXDC | interactor | 1 | 0 | 0 | Glyco_hydro_20 (PF00728, IPR015883): Glycosyl hydrolase family 20, catalytic domain |
54 |
HNRNPK | oncoprotein | 30 | 0.367 | 84.133 | ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
55 |
HSPB1 | oncoprotein | 21 | 0.426 | 46.125 | HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family |
56 |
HUWE1 | oncoprotein | 25 | 0.337 | 87.360 | BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414) |
57 |
IGSF8 | oncoprotein | 12 | 0.515 | 9.265 | V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
58 |
ITGA4 | interactor | 25 | 0.428 | 44.508 | FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha |
59 |
JUN | oncoprotein | 9 | 0.571 | 7.319 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor |
60 |
KTN1 | oncoprotein | 6 | 0.667 | 2.952 | ETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP) Fez1 (PF06818): Fez1 Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family Fzo_mitofusin (PF04799, IPR006884): fzo-like conserved region HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper IncA (PF04156, IPR007285): IncA protein OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) PTPS (PF01242, IPR007115): 6-pyruvoyl tetrahydropterin synthase Spectrin (PF00435, IPR002017): Spectrin repeat TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) Fimbrial_PilY2 (PF14481, IPR029497): Type 4 fimbrial biogenesis protein PilY2 Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 |
61 |
LIMA1 | suppressor | 10 | 0.400 | 17.510 | LIM (PF00412, IPR001781, SM00132): LIM domain ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain |
62 |
LMNA | protein found in more fusions | 21 | 0.311 | 75.535 | Filament (PF00038, IPR001664): Intermediate filament protein LTD (PF00932, IPR001322): Lamin Tail Domain Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) |
63 |
MAP1B | interactor | 7 | 0.381 | 4.202 | DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) MAP1B_neuraxin (PF00414, IPR000102): Neuraxin and MAP1B repeat Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup Striatin (PF08232, IPR013258): Striatin family IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal |
64 |
MATR3 | interactor | 15 | 0.527 | 12.608 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM60A (PF15396, IPR026065): Protein Family FAM60A |
65 |
MAX | suppressor | 4 | 0.667 | 0.667 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain SlyX (PF04102, IPR007236): SlyX |
66 |
MCCC1 | interactor | 5 | 0.700 | 1.154 | Biotin_carb_C (PF02785, IPR005482, SM00878): Biotin carboxylase C-terminal domain Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme Biotin_carb_N (PF00289, IPR005481): Biotin carboxylase, N-terminal domain CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain |
67 |
MCM2 | oncoprotein | 37 | 0.349 | 179.430 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
68 |
NPM1 | suppressor | 39 | 0.343 | 208.037 | Nucleoplasmin (PF03066): Nucleoplasmin SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain |
69 |
NTRK1 | oncoprotein | 56 | 0.187 | 743.819 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
70 |
OARD1 | interactor | 3 | 0.667 | 0.667 | 3HCDH_N (PF02737, IPR006176): 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Macro (PF01661, IPR002589, SM00506): Macro domain |
71 |
PCBP1 | oncoprotein | 24 | 0.428 | 53.861 | Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein KH_2 (PF07650, IPR004044): KH domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
72 |
PKM | oncoprotein | 27 | 0.399 | 87.342 | PK (PF00224, IPR015793): Pyruvate kinase, barrel domain PK_C (PF02887, IPR015795): Pyruvate kinase, alpha/beta domain |
73 |
PKN2 | interactor | 9 | 0.393 | 9.287 | C2 (PF00168, IPR000008, SM00239): C2 domain HR1 (PF02185, IPR011072, SM00742): Hr1 repeat Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2 |
74 |
POT1 | interactor | 7 | 0.467 | 5.019 | POT1 (PF02765, IPR011564, SM00976): Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain POT1PC (PF16686, IPR032042): ssDNA-binding domain of telomere protection protein |
75 |
PPME1 | protein found in more fusions | 5 | 0.833 | 0.200 | Abhydrolase_6 (PF12697, IPR000073): Alpha/beta hydrolase family |
76 |
PSMD10 | interactor | 6 | 0.400 | 6.400 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) |
77 |
RAD21 | oncoprotein | 9 | 0.528 | 7.997 | Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
78 |
RAD52 | oncoprotein | 4 | 1.000 | 0 | Rad52_Rad22 (PF04098, IPR007232): Rad52/22 family double-strand break repair protein DUF2335 (PF10097, IPR019284): Predicted membrane protein (DUF2335) |
79 |
RELA | oncoprotein | 12 | 0.400 | 23.159 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
80 |
RNF2 | interactor | 21 | 0.200 | 96.844 | zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
81 |
RPL15 | interactor | 15 | 0.638 | 7.620 | Ribosomal_L15e (PF00827, IPR000439): Ribosomal L15 |
82 |
RPL18 | interactor | 20 | 0.484 | 19.368 | Ribosomal_L18 (PF17135): Ribosomal protein 60S L18 and 50S L18e |
83 |
RTN4 | suppressor | 9 | 0.464 | 11.119 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain Reticulon (PF02453, IPR003388): Reticulon Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein |
84 |
SF3A3 | interactor | 15 | 0.324 | 36.157 | DUF3449 (PF11931, IPR024598): Domain of unknown function (DUF3449) SF3a60_bindingd (PF12108, IPR021966): Splicing factor SF3a60 binding domain Telomere_Sde2_2 (PF13297): Telomere stability C-terminal PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal SF3A3 (PF16837, IPR031774): Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 |
85 |
SIAH1 | suppressor | 7 | 0.467 | 4.783 | Sina (PF03145, IPR018121): Seven in absentia protein family |
86 |
SIAH2 | oncoprotein | 5 | 0.667 | 1.500 | Sina (PF03145, IPR018121): Seven in absentia protein family zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
87 |
SLC33A1 | interactor | 3 | 0.667 | 0.500 | Acatn (PF13000, IPR024371): Acetyl-coenzyme A transporter 1 |
88 |
SMURF1 | interactor | 11 | 0.378 | 7.197 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
89 |
SQSTM1 | oncoprotein | 13 | 0.409 | 23.763 | PB1 (PF00564, IPR000270, SM00666): PB1 domain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type UBA_5 (PF16577, IPR015940): UBA domain |
90 |
SRRM2 | interactor | 16 | 0.458 | 17.595 | cwf21 (PF08312, IPR013170, SM01115): cwf21 domain DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Pap_E4 (PF02711, IPR003861): E4 protein RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 CTD (PF12815, IPR024945, SM01104): Spt5 C-terminal nonapeptide repeat binding Spt4 DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) |
91 |
SRRT | interactor | 11 | 0.491 | 11.462 | ARS2 (PF04959, IPR007042): Arsenite-resistance protein 2 DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit Macoilin (PF09726, IPR019130): Transmembrane protein DUF3546 (PF12066, IPR021933): Domain of unknown function (DUF3546) DUF4187 (PF13821, IPR025239): Domain of unknown function (DUF4187) |
92 |
STAU1 | protein found in more fusions | 23 | 0.455 | 32.107 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain |
93 |
STMN1 | interactor | 9 | 0.472 | 7.368 | Stathmin (PF00836, IPR000956): Stathmin family |
94 |
SUPT5H | interactor | 10 | 0.489 | 7.064 | KOW (PF00467, IPR005824, SM00739): KOW motif Ribonuc_P_40 (PF08584, IPR013893): Ribonuclease P 40kDa (Rpp40) subunit Spt5-NGN (PF03439, IPR005100): Early transcription elongation factor of RNA pol II, NGN section Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF3912 (PF13051, IPR025023): Protein of unknown function (DUF3912) |
95 |
SYNPO | interactor | 6 | 0.667 | 3.500 | Calsarcin (PF05556, IPR008438): Calcineurin-binding protein (Calsarcin) |
96 |
TERF1 | interactor | 11 | 0.400 | 15.537 | TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
97 |
TINF2 | interactor | 7 | 0.467 | 5.786 | TINF2_N (PF14973, IPR029400): TERF1-interacting nuclear factor 2 N-terminus |
98 |
TPR | oncoprotein | 14 | 0.527 | 16.385 | Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus ZapB (PF06005, IPR009252): Cell division protein ZapB Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 XhlA (PF10779, IPR019715): Haemolysin XhlA ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein DUF3373 (PF11853, IPR021803): Protein of unknown function (DUF3373) DUF4107 (PF13389, IPR025180): Protein of unknown function (DUF4107) JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082) |
99 |
TPT1 | interactor | 4 | 0.500 | 0.611 | TCTP (PF00838, IPR018105): Translationally controlled tumour protein |
100 |
U2AF2 | protein found in more fusions | 25 | 0.460 | 45.161 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
101 |
VARS | interactor | 22 | 0.260 | 118.592 | Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V) Val_tRNA-synt_C (PF10458, IPR019499): Valyl tRNA synthetase tRNA binding arm SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
102 |
VCAM1 | interactor | 21 | 0.381 | 35.195 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
103 |
VIM | suppressor | 21 | 0.337 | 52.471 | Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region |
104 |
ZW10 | interactor | 7 | 0.429 | 6.774 | Zw10 (PF06248, IPR009361): Centromere/kinetochore Zw10 DUF2203 (PF09969, IPR018699): Uncharacterized conserved protein (DUF2203) |