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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins DNPH1 (from a repository: Mon Dec 5 03:32:54 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)10
The number (and %) of the onco-proteins2 (20.00 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)17 (37.78 %)
The number (and %) of affected PPIs10 (58.82 %)
The number of possible different fusions4
PPI diameter2
PPI radius1
The average degree of PPI2.400
Assortativity coefficient-0.2416
The network average Clustering coefficient0.475
The number (and %) of a zero Clustering coefficients4 (40.00 %)
The number (and %) of a zero Betweenness Centrality8 (80.00 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: DNPH1 All fusions
: BF591833;
Proteins found in more fusions DNPH1 (see 1 fusions); UBA1 (see 2 fusions); PRDX1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 DNPH1parental protein100.08365.000Nuc_deoxyrib_tr (PF05014, IPR007710): Nucleoside 2-deoxyribosyltransferase
2 DSTNinteractor100Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
3 PILRAinteractor100SKG6 (PF08693, IPR014805): Transmembrane alpha-helix domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
G6B (PF15096, IPR028070): G6B family
4 POT1interactor31.0000POT1 (PF02765, IPR011564, SM00976): Telomeric single stranded DNA binding POT1/CDC13
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
POT1PC (PF16686, IPR032042): ssDNA-binding domain of telomere protection protein
5 PRDX1oncoprotein31.0000AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
6 SSU72interactor100Ssu72 (PF04722, IPR006811): Ssu72-like protein
7 TERF1interactor40.6671.000TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
8 UBA1protein found in more fusions200ThiF (PF00899, IPR000594): ThiF family
E1_UFD (PF09358, IPR018965, SM00985): Ubiquitin fold domain
UBA_e1_thiolCys (PF10585, IPR019572): Ubiquitin-activating enzyme active site
9 UBR1interactor21.0000ATPase_2 (PF01637, IPR011579): ATPase domain predominantly from Archaea
ClpS (PF02617, IPR003769): ATP-dependent Clp protease adaptor protein ClpS
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
10 ZNF593interactor21.0000DUF3073 (PF11273, IPR021426): Protein of unknown function (DUF3073)
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding

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