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Visible interactions: all affected independent (normal) missing (in fusions) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)157
The number (and %) of the onco-proteins37 (23.57 %)
The number (and %) of the tumor suppressors17 (10.83 %)
Total number of binary PPIs (saturation %)3088 (25.22 %)
The number (and %) of affected PPIs156 (5.05 %)
The number of possible different fusions29
PPI diameter5
PPI radius3
The average degree of PPI38.815
Assortativity coefficient0.1678
The network average Clustering coefficient0.622
The number (and %) of a zero Clustering coefficients13 (8.28 %)
The number (and %) of a zero Betweenness Centrality20 (12.74 %)

ACTIVE INTERACTORS
MISSING INTERACTORS (in fusions)


List of the fusions

PPI for parental proteins: DMD,RPLP1 All fusions
: BU624867;
Proteins found in more fusions NPM1 (see 1 fusions); CUL1 (see 3 fusions); RPS5/RPL14 (see 1 fusions); GAN (see 1 fusions); MAP3K5 (see 1 fusions); HNRNPU/RPL24 (see 1 fusions); RPLP2 (see 1 fusions); NEDD4 (see 1 fusions); IBTK (see 2 fusions); APP (see 4 fusions); CUL4A (see 4 fusions); RPS24/RPS23 (see 1 fusions); RPL27/RPS6 (see 1 fusions); APP/ALB (see 2 fusions); MARK2 (see 2 fusions); EEF1A1/RPL12 (see 1 fusions); RPL38/RPL3 (see 1 fusions); CSNK2A1 (see 1 fusions); RPS19/RPS14 (see 1 fusions); EEF1A1 (see 1 fusions); GSK3B (see 1 fusions); CTNNA1 (see 3 fusions); CUL3 (see 1 fusions); AHNAK (see 2 fusions); COPS5 (see 1 fusions); NUDT21 (see 2 fusions); SAT1 (see 5 fusions); MCM2 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 DMDparental protein330.0643423.328CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
EF-hand_2 (PF09068, IPR015153): EF hand
EF-hand_3 (PF09069, IPR015154): EF-hand
FliD_N (PF02465, IPR003481): Flagellar hook-associated protein 2 N-terminus
IncA (PF04156, IPR007285): IncA protein
Spectrin (PF00435, IPR002017): Spectrin repeat
WW (PF00397, IPR001202, SM00456): WW domain
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
DinB_2 (PF12867, IPR024775): DinB superfamily
CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
2 RPLP1parental protein1230.3556076.412Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
3 ABL1oncoprotein90.14330.768Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2
4 ACTA1interactor80.10771.169Actin (PF00022, IPR004000, SM00268): Actin
5 ADRB2interactor130.34840.5537tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
6 AHNAKsuppressor70.40029.224DUF945 (PF06097, IPR010352): Bacterial protein of unknown function (DUF945)
ELFV_dehydrog_N (PF02812, IPR006097): Glu/Leu/Phe/Val dehydrogenase, dimerisation domain
T2SSN (PF01203, IPR022792): Type II secretion system (T2SS), protein N
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
TT_ORF2a (PF08197, IPR013267): pORF2a truncated protein
DUF2993 (PF11209, IPR021373): Protein of unknown function (DUF2993)
DUF4097 (PF13349, IPR025164): Putative adhesin
Ntox37 (PF15535, IPR029108): Bacterial toxin 37
7 ALBprotein found in more fusions40.16738.452Serum_albumin (PF00273, IPR014760, SM00103): Serum albumin family
8 ANKRD13Binteractor100UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
GPCR_chapero_1 (PF11904, IPR021832): GPCR-chaperone
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
9 APPprotein found in more fusions420.3541015.060APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
10 ARRB1interactor220.381266.217Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
11 ARRB2interactor460.548342.210Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
12 ASCC2interactor21.0000CUE (PF02845, IPR003892, SM00546): CUE domain
BLOC1S3 (PF15753, IPR017245): Biogenesis of lysosome-related organelles complex 1 subunit 3
13 ATP5J2interactor200.733WRW (PF10206, IPR019344): Mitochondrial F1F0-ATP synthase, subunit f
14 BMI1oncoprotein100.22248.594zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
15 BRD7suppressor21.0000HcyBio (PF01837, IPR002708): Homocysteine biosynthesis enzyme, sulfur-incorporation
GntR (PF00392, IPR000524, SM00345): Bacterial regulatory proteins, gntR family
Presenilin (PF01080, IPR001108): Presenilin
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
DUF3512 (PF12024, IPR021900): Domain of unknown function (DUF3512)
MAJIN (PF15077, IPR027816): Membrane-anchored junction protein
16 C11orf58interactor30.33382.336DUF3408 (PF11888, IPR021823): Protein of unknown function (DUF3408)
SMAP (PF15477, IPR028124): Small acidic protein family
17 CAND1interactor740.775145.644Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981)
HEAT (PF02985, IPR000357): HEAT repeat
TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20)
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
18 CD4suppressor110.6896.086ATP1G1_PLM_MAT8 (PF02038, IPR000272): ATP1G1/PLM/MAT8 family
C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
CD4-extracel (PF09191, IPR015274): CD4, extracellular
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Tcell_CD4_C (PF12104, IPR021963): T cell CD4 receptor C terminal region
19 CDC25Aoncoprotein70.38141.796M-inducer_phosp (PF06617, IPR000751): M-phase inducer phosphatase
Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain
20 CDIPTinteractor30.6670.970A2M_N (PF01835, IPR002890): MG2 domain
Dynactin (PF12455, IPR022157): Dynein associated protein
21 CDK2AP2interactor200.970CDK2AP (PF09806, IPR019187): Cyclin-dependent kinase 2-associated protein
22 CLIC1interactor21.0000GST_N_2 (PF13409, IPR004045): Glutathione S-transferase, N-terminal domain
GST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain
23 COPS5protein found in more fusions730.745153.673JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
24 COPS6interactor310.76140.658DUF320 (PF03777, IPR005528): Small secreted domain (DUF320)
JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
25 CSNK2A1oncoprotein200.49141.267Pkinase (PF00069, IPR000719): Protein kinase domain
26 CTNNA1oncoprotein100.44460.164Vinculin (PF01044, IPR006077): Vinculin family
27 CTNNAL1interactor100Vinculin (PF01044, IPR006077): Vinculin family
28 CUL1suppressor710.760208.457Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
29 CUL2suppressor570.753125.709Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
30 CUL3protein found in more fusions800.616610.649Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
31 CUL4Aprotein found in more fusions300.8187.408Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
32 CUL4Boncoprotein470.775246.433Cullin (PF00888, IPR001373, SM00182): Cullin family
EBP50_C (PF09007, IPR015098): EBP50, C-terminal
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain
MDFI (PF15316, IPR026134): MyoD family inhibitor
33 CUL5suppressor560.78479.941Cullin (PF00888, IPR001373, SM00182): Cullin family
GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
34 DAG1interactor100DAG1 (PF05454, IPR008465): Dystroglycan (Dystrophin-associated glycoprotein 1)
35 DISC1interactor30.66710.293HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
Mnd1 (PF03962, IPR005647): Mnd1 family
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Tropomyosin (PF00261, IPR000533): Tropomyosin
UVR (PF02151, IPR001943): UvrB/uvrC motif
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
36 DTNAinteractor40.6673.354ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CRISPR_Cse2 (PF09485, IPR013382): CRISPR-associated protein Cse2 (CRISPR_cse2)
EF-hand_2 (PF09068, IPR015153): EF hand
EF-hand_3 (PF09069, IPR015154): EF-hand
PMC2NT (PF08066, IPR012588): PMC2NT (NUC016) domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
37 DTNBinteractor200EF-hand_2 (PF09068, IPR015153): EF hand
EF-hand_3 (PF09069, IPR015154): EF-hand
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
Ax_dynein_light (PF10211, IPR019347): Axonemal dynein light chain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
SOGA (PF11365, IPR027881): Protein SOGA
38 EEF1A1suppressor570.679251.291GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
39 EIF3Aoncoprotein140.7366.758DUF1003 (PF06210, IPR010406): Protein of unknown function (DUF1003)
Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region
PCI (PF01399, IPR000717, SM00088): PCI domain
AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
40 FARSBinteractor60.6004.318B3_4 (PF03483, IPR005146, SM00873): B3/4 domain
B5 (PF03484, IPR005147, SM00874): tRNA synthetase B5 domain
41 FUSsuppressor320.577163.394Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Limkain-b1 (PF11608, IPR024582): Limkain b1
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
42 GANprotein found in more fusions200.789180.709BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
43 GEMIN7interactor100Gemin7 (PF11095, IPR020338): Gem-associated protein 7 (Gemin7)
SUZ-C (PF12901, IPR024642): SUZ-C motif
44 GSK3Bsuppressor90.35729.710Pkinase (PF00069, IPR000719): Protein kinase domain
45 HAUS1interactor31.0000THP2 (PF09432, IPR018557): Tho complex subunit THP2
XhlA (PF10779, IPR019715): Haemolysin XhlA
DUF3496 (PF12001, IPR021885): Domain of unknown function (DUF3496)
46 HNRNPUprotein found in more fusions730.719219.878CDC45 (PF02724, IPR003874): CDC45-like protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
47 HSPA5oncoprotein290.51984.592HSP70 (PF00012, IPR013126): Hsp70 protein
48 IBTKprotein found in more fusions91.0000BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
Ank_5 (PF13857): Ankyrin repeats (many copies)
49 IFIT1interactor21.0000TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
Sec16_C (PF12931, IPR024298): Sec23-binding domain of Sec16
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
DUF4268 (PF14088, IPR025364): Domain of unknown function (DUF4268)
TPR_19 (PF14559): Tetratricopeptide repeat
50 IFIT2interactor30.6671.206TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
HTH_WhiA (PF02650, IPR023054): WhiA C-terminal HTH domain
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
Mad3_BUB1_I_2 (PF17014, IPR031522): Putative Mad3/BUB1 like region 1 protein
51 IGBP1interactor50.30010.675TAP42 (PF04177, IPR007304): TAP42-like family
52 KCNJ12interactor50.5005.292IRK (PF01007, IPR016449): Inward rectifier potassium channel
IRK_N (PF08466, IPR013673): Inward rectifier potassium channel N-terminal
53 KCNJ4interactor21.0000IRK (PF01007, IPR016449): Inward rectifier potassium channel
IRK_N (PF08466, IPR013673): Inward rectifier potassium channel N-terminal
54 KIF15interactor209.531Bcr-Abl_Oligo (PF09036, IPR015123): Bcr-Abl oncoprotein oligomerisation domain
DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
SlyX (PF04102, IPR007236): SlyX
STE (PF02200, IPR003120, SM00424): STE like transcription factor
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
FlxA (PF14282, IPR025577): FlxA-like protein
HMMR_C (PF15908, IPR031794): Hyaluronan mediated motility receptor C-terminal
55 LOC101929876interactor530.9811.058NA
56 LPAR6interactor1007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
MscS_TM (PF12794, IPR025692): Mechanosensitive ion channel inner membrane domain 1
57 LRIF1interactor80.28617.045LRIF1 (PF15741, IPR026191): Ligand-dependent nuclear receptor-interacting factor 1
58 MAP1LC3Binteractor30.6670.214Atg8 (PF02991, IPR004241): Autophagy protein Atg8 ubiquitin like
59 MAP3K5oncoprotein70.53313.406Pkinase (PF00069, IPR000719): Protein kinase domain
DUF4071 (PF13281, IPR025136): Domain of unknown function (DUF4071)
60 MARK2protein found in more fusions60.30064.071DUF702 (PF05142, IPR007818): Domain of unknown function (DUF702)
KA1 (PF02149, IPR001772): Kinase associated domain 1
Pkinase (PF00069, IPR000719): Protein kinase domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
61 MCM2oncoprotein730.5401440.955AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
62 MGMTinteractor60.6671.987DNA_binding_1 (PF01035, IPR014048): 6-O-methylguanine DNA methyltransferase, DNA binding domain
Methyltransf_1N (PF02870, IPR008332): 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain
63 MPC2interactor100MPC (PF03650, IPR005336): Uncharacterised protein family (UPF0041)
64 MRPS35interactor41.0000MRP-S28 (PF10213, IPR019349): Mitochondrial ribosomal subunit protein
65 NEDD4suppressor150.242301.430Rota_NS26 (PF01525, IPR002512): Rotavirus NS26
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
66 NEDD8interactor350.74760.523ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
67 NFX1interactor100.55689.067R3H (PF01424, IPR001374, SM00393): R3H domain
XPG_I (PF00867, IPR006086, SM00484): XPG I-region
zf-NF-X1 (PF01422, IPR000967, SM00438): NF-X1 type zinc finger
68 NOS1interactor21.0000FAD_binding_1 (PF00667, IPR003097): FAD binding domain
Flavodoxin_1 (PF00258, IPR008254): Flavodoxin
NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain
NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
69 NPM1suppressor770.645328.760Nucleoplasmin (PF03066): Nucleoplasmin
SDA1 (PF05285, IPR007949): SDA1
NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
70 NSFinteractor60.4003.410AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
ATPase (PF06745, IPR014774): KaiC
AAA_19 (PF13245): Part of AAA domain
71 NUDT21protein found in more fusions130.47027.642NUDIX_2 (PF13869, IPR016706): Nucleotide hydrolase
72 NUDT3interactor100NUDIX (PF00293, IPR000086): NUDIX domain
73 NUP58interactor100Nucleoporin_FG2 (PF15967): Nucleoporin FG repeated region
74 PFDN1interactor60.20052.965Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
75 PPP2CBsuppressor40.3337.807Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
76 PTNoncoprotein80.28619.406PTN_MK_C (PF01091, IPR020090): PTN/MK heparin-binding protein family, C-terminal domain
PTN_MK_N (PF05196, IPR020089): PTN/MK heparin-binding protein family, N-terminal domain
77 PTRFinteractor30.33313.990PTRF_SDPR (PF15237, IPR026752): PTRF/SDPR family
78 RCHY1suppressor41.0000C1_2 (PF03107, IPR004146): C1 domain
zf-CHY (PF05495, IPR008913): CHY zinc finger
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
zinc_ribbon_6 (PF14599): Zinc-ribbon
79 RNF2interactor530.597284.401zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
80 RPA2oncoprotein290.510131.767RPA_C (PF08784, IPR014892): Replication protein A C terminal
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
81 RPL10suppressor710.83776.110Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
82 RPL10Ainteractor720.86032.054Ribosomal_L1 (PF00687, IPR028364): Ribosomal protein L1p/L10e family
83 RPL11suppressor750.82643.717Ribosomal_L5 (PF00281, IPR002132): Ribosomal protein L5
Ribosomal_L5_C (PF00673, IPR002132): ribosomal L5P family C-terminus
84 RPL12protein found in more fusions720.85333.736Ribosomal_L11 (PF00298, IPR020783): Ribosomal protein L11, RNA binding domain
Ribosomal_L11_N (PF03946, IPR020784): Ribosomal protein L11, N-terminal domain
85 RPL13interactor700.828106.793Ribosomal_L13e (PF01294, IPR001380): Ribosomal protein L13e
86 RPL14protein found in more fusions730.84529.903KOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14
UPF0688 (PF15772, IPR031530): UPF0688 family
87 RPL15interactor780.79857.863Ribosomal_L15e (PF00827, IPR000439): Ribosomal L15
88 RPL18interactor780.79197.945Ribosomal_L18 (PF17135): Ribosomal protein 60S L18 and 50S L18e
89 RPL18Ainteractor690.88226.453Ribosomal_L18A (PF01775, IPR023573): Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
90 RPL19interactor760.81159.987DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682)
Ribosomal_L19e (PF01280, IPR000196): Ribosomal protein L19e
91 RPL21interactor760.83738.104Ribosomal_L21e (PF01157, IPR001147): Ribosomal protein L21e
92 RPL23interactor710.86330.329Ribosomal_L14 (PF00238, IPR000218): Ribosomal protein L14p/L23e
93 RPL23Ainteractor780.81848.059Ribosomal_L23 (PF00276, IPR013025): Ribosomal protein L23
Ribosomal_L23eN (PF03939, IPR005633): Ribosomal protein L23, N-terminal domain
94 RPL24protein found in more fusions760.818159.459MAS20 (PF02064, IPR002056): MAS20 protein import receptor
Ribosomal_L24e (PF01246, IPR000988): Ribosomal protein L24e
95 RPL27protein found in more fusions700.90613.177Ribosomal_L27e (PF01777, IPR001141): Ribosomal L27e protein family
96 RPL27Ainteractor650.92210.030Ribosomal_L27A (PF00828, IPR021131): Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
97 RPL28interactor390.87011.604Ribosomal_L28e (PF01778, IPR029004): Ribosomal L28e protein family
98 RPL29interactor300.9540.943BRF1 (PF07741, IPR011665): Brf1-like TBP-binding domain
Ribosomal_L29e (PF01779, IPR002673): Ribosomal L29e protein family
99 RPL3protein found in more fusions740.83161.991Ribosomal_L3 (PF00297, IPR000597): Ribosomal protein L3
100 RPL30interactor690.88921.400NCBP3 (PF10309, IPR019416): Nuclear cap-binding protein subunit 3
101 RPL31interactor750.814146.212Ribosomal_L31e (PF01198, IPR000054): Ribosomal protein L31e
102 RPL34interactor530.91510.760Redoxin (PF08534, IPR013740): Redoxin
Ribosomal_L34e (PF01199, IPR008195): Ribosomal protein L34e
103 RPL36interactor660.90116.309Ribosomal_L36e (PF01158, IPR000509): Ribosomal protein L36e
104 RPL37Ainteractor680.89286.446Ribosomal_L37ae (PF01780, IPR002674): Ribosomal L37ae protein family
105 RPL38protein found in more fusions680.86222.518Ribosomal_L38e (PF01781, IPR002675): Ribosomal L38e protein family
106 RPL4interactor800.78074.095Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family
Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain
107 RPL5suppressor770.82947.570Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region
Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18
108 RPL6interactor820.740146.906Ribosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e
Ribosomal_L6e_N (PF03868, IPR005568): Ribosomal protein L6, N-terminal domain
109 RPL7interactor750.812129.078Ribosomal_L30 (PF00327, IPR016082): Ribosomal protein L30p/L7e
Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain
110 RPL7Ainteractor720.81675.159Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
111 RPL9interactor750.84034.997Ribosomal_L6 (PF00347, IPR020040): Ribosomal protein L6
112 RPLP0interactor820.743156.084Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10
113 RPLP0P6interactor550.9435.857NA
114 RPLP2protein found in more fusions730.84329.857Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
115 RPS10interactor770.781123.734S10_plectin (PF03501, IPR005326): Plectin/S10 domain
116 RPS11interactor730.85737.753Ribosomal_S17 (PF00366, IPR000266): Ribosomal protein S17
Ribosomal_S17_N (PF16205, IPR032440): Ribosomal_S17 N-terminal
117 RPS13interactor730.85837.066Ribosomal_S13_N (PF08069, IPR012606): Ribosomal S13/S15 N-terminal domain
Ribosomal_S15 (PF00312, IPR000589): Ribosomal protein S15
118 RPS14protein found in more fusions750.82352.792Ribosomal_S11 (PF00411, IPR001971): Ribosomal protein S11
119 RPS15interactor600.9276.360Ribosomal_S19 (PF00203, IPR002222): Ribosomal protein S19
Prok_Ub (PF14454, IPR032866): Prokaryotic Ubiquitin
120 RPS15Ainteractor760.81377.596Ribosomal_S8 (PF00410, IPR000630): Ribosomal protein S8
121 RPS16interactor790.79288.484Ribosomal_S9 (PF00380, IPR000754): Ribosomal protein S9/S16
122 RPS17interactor540.86926.627Ribosomal_S17e (PF00833, IPR001210): Ribosomal S17
123 RPS18interactor720.83657.630Ribosomal_S13 (PF00416, IPR001892): Ribosomal protein S13/S18
124 RPS19protein found in more fusions760.799189.460Ribosomal_S19e (PF01090, IPR001266): Ribosomal protein S19e
125 RPS2interactor810.752147.857Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain
Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain
126 RPS20interactor730.82649.056Ribosomal_S10 (PF00338, IPR027486): Ribosomal protein S10p/S20e
127 RPS21interactor600.90752.352Ribosomal_S21e (PF01249, IPR001931): Ribosomal protein S21e
128 RPS23protein found in more fusions730.83645.828Ribosom_S12_S23 (PF00164, IPR006032): Ribosomal protein S12/S23
129 RPS24protein found in more fusions680.88116.182Fascin (PF06268, IPR022768): Fascin domain
Ribosomal_S24e (PF01282, IPR001976): Ribosomal protein S24e
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
130 RPS25interactor750.82660.400Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein
131 RPS26interactor670.84791.687Ribosomal_S26e (PF01283, IPR000892): Ribosomal protein S26e
132 RPS27Ainteractor450.86525.077DUF1049 (PF06305, IPR010445): Protein of unknown function (DUF1049)
133 RPS3interactor820.734149.357KH_2 (PF07650, IPR004044): KH domain
Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain
134 RPS3Ainteractor830.734188.077Ribosomal_S3Ae (PF01015, IPR001593): Ribosomal S3Ae family
135 RPS4Xinteractor780.793181.019KOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_S4e (PF00900, IPR013845): Ribosomal family S4e
RS4NT (PF08071, IPR013843): RS4NT (NUC023) domain
S4 (PF01479, IPR002942, SM00363): S4 domain
40S_S4_C (PF16121, IPR032277): 40S ribosomal protein S4 C-terminus
136 RPS5protein found in more fusions720.82877.319Ribosomal_S7 (PF00177, IPR023798): Ribosomal protein S7p/S5e
137 RPS6protein found in more fusions770.808106.566Ribosomal_S6e (PF01092, IPR001377): Ribosomal protein S6e
DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574)
138 RPS6KA6suppressor200.970Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
139 RPS7interactor720.84357.646Ribosomal_S7e (PF01251, IPR000554): Ribosomal protein S7e
140 RPS8interactor820.737204.271Ribosomal_S8e (PF01201, IPR022309): Ribosomal protein S8e
141 RPSAinteractor760.781162.846Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2
40S_SA_C (PF16122, IPR032281): 40S ribosomal protein SA C-terminus
142 SAT1protein found in more fusions60.4006.928Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
143 SIRT7interactor440.732113.546DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
144 SNTA1interactor60.333120.830PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
PH (PF00169, IPR001849, SM00233): PH domain
145 SNTB1interactor21.0000GATA-N (PF05349, IPR008013): GATA-type transcription activator, N-terminal
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
PH (PF00169, IPR001849, SM00233): PH domain
146 SNTB2interactor40.50032.020PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
PH (PF00169, IPR001849, SM00233): PH domain
147 TAB1interactor70.52412.545PP2C (PF00481, IPR001932): Protein phosphatase 2C
148 TERF1interactor140.385146.036TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
149 TERF2interactor90.25063.202Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain
TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
TERF2_RBM (PF16772, IPR031902): Telomeric repeat-binding factor 2 Rap1-binding motif
150 TMEM165interactor30.6670.037Phage_holin_3_6 (PF07332, IPR009937): Putative Actinobacterial Holin-X, holin superfamily III
UPF0016 (PF01169, IPR001727): Uncharacterized protein family UPF0016
151 TPT1interactor30.3331.472TCTP (PF00838, IPR018105): Translationally controlled tumour protein
152 TRAF3IP1interactor80.250101.706MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
153 TUBB2Ainteractor140.209231.353Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
154 UBE2D3interactor90.32131.603UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
155 UBL4Ainteractor650.797148.750ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
156 XPO1interactor440.550947.818CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
157 XRCC6oncoprotein200.322362.851Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
SAP (PF02037, IPR003034, SM00513): SAP domain

B a c k    t o    T o p ⇑


List of missing interactors (in fusions)

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ACTA1interactorActin (PF00022, IPR004000, SM00268): ActinBU624867
2 AHNAKsuppressorDUF945 (PF06097, IPR010352): Bacterial protein of unknown function (DUF945)
ELFV_dehydrog_N (PF02812, IPR006097): Glu/Leu/Phe/Val dehydrogenase, dimerisation domain
T2SSN (PF01203, IPR022792): Type II secretion system (T2SS), protein N
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
TT_ORF2a (PF08197, IPR013267): pORF2a truncated protein
DUF2993 (PF11209, IPR021373): Protein of unknown function (DUF2993)
DUF4097 (PF13349, IPR025164): Putative adhesin
Ntox37 (PF15535, IPR029108): Bacterial toxin 37
BU624867
3 ALBinteractorSerum_albumin (PF00273, IPR014760, SM00103): Serum albumin familyBU624867
4 APPinteractorAPP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
BU624867
5 ARRB1interactorArrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
BU624867
6 ARRB2interactorArrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
BU624867
7 ASCC2interactorCUE (PF02845, IPR003892, SM00546): CUE domain
BLOC1S3 (PF15753, IPR017245): Biogenesis of lysosome-related organelles complex 1 subunit 3
BU624867
8 ATP5J2interactorWRW (PF10206, IPR019344): Mitochondrial F1F0-ATP synthase, subunit fBU624867
9 BMI1oncoproteinzf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
BU624867
10 BRD7suppressorHcyBio (PF01837, IPR002708): Homocysteine biosynthesis enzyme, sulfur-incorporation
GntR (PF00392, IPR000524, SM00345): Bacterial regulatory proteins, gntR family
Presenilin (PF01080, IPR001108): Presenilin
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
DUF3512 (PF12024, IPR021900): Domain of unknown function (DUF3512)
MAJIN (PF15077, IPR027816): Membrane-anchored junction protein
BU624867
11 C11orf58interactorDUF3408 (PF11888, IPR021823): Protein of unknown function (DUF3408)
SMAP (PF15477, IPR028124): Small acidic protein family
BU624867
12 CD4suppressorATP1G1_PLM_MAT8 (PF02038, IPR000272): ATP1G1/PLM/MAT8 family
C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
CD4-extracel (PF09191, IPR015274): CD4, extracellular
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Tcell_CD4_C (PF12104, IPR021963): T cell CD4 receptor C terminal region
BU624867
13 CDC25AoncoproteinM-inducer_phosp (PF06617, IPR000751): M-phase inducer phosphatase
Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain
BU624867
14 CDK2AP2interactorCDK2AP (PF09806, IPR019187): Cyclin-dependent kinase 2-associated proteinBU624867
15 CLIC1interactorGST_N_2 (PF13409, IPR004045): Glutathione S-transferase, N-terminal domain
GST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain
BU624867
16 COPS5interactorJAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin proteaseBU624867
17 COPS6interactorDUF320 (PF03777, IPR005528): Small secreted domain (DUF320)
JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
BU624867
18 CTNNA1oncoproteinVinculin (PF01044, IPR006077): Vinculin familyBU624867
19 CTNNAL1interactorVinculin (PF01044, IPR006077): Vinculin familyBU624867
20 DAG1interactorDAG1 (PF05454, IPR008465): Dystroglycan (Dystrophin-associated glycoprotein 1)BU624867
21 DISC1interactorHALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
Mnd1 (PF03962, IPR005647): Mnd1 family
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Tropomyosin (PF00261, IPR000533): Tropomyosin
UVR (PF02151, IPR001943): UvrB/uvrC motif
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
BU624867
22 DMDparental proteinCH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
EF-hand_2 (PF09068, IPR015153): EF hand
EF-hand_3 (PF09069, IPR015154): EF-hand
FliD_N (PF02465, IPR003481): Flagellar hook-associated protein 2 N-terminus
IncA (PF04156, IPR007285): IncA protein
Spectrin (PF00435, IPR002017): Spectrin repeat
WW (PF00397, IPR001202, SM00456): WW domain
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
DinB_2 (PF12867, IPR024775): DinB superfamily
CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
BU624867
23 DTNAinteractorATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CRISPR_Cse2 (PF09485, IPR013382): CRISPR-associated protein Cse2 (CRISPR_cse2)
EF-hand_2 (PF09068, IPR015153): EF hand
EF-hand_3 (PF09069, IPR015154): EF-hand
PMC2NT (PF08066, IPR012588): PMC2NT (NUC016) domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
BU624867
24 DTNBinteractorEF-hand_2 (PF09068, IPR015153): EF hand
EF-hand_3 (PF09069, IPR015154): EF-hand
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
Ax_dynein_light (PF10211, IPR019347): Axonemal dynein light chain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
SOGA (PF11365, IPR027881): Protein SOGA
BU624867
25 EEF1A1suppressorGTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
BU624867
26 EIF3AoncoproteinDUF1003 (PF06210, IPR010406): Protein of unknown function (DUF1003)
Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region
PCI (PF01399, IPR000717, SM00088): PCI domain
AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
BU624867
27 FARSBinteractorB3_4 (PF03483, IPR005146, SM00873): B3/4 domain
B5 (PF03484, IPR005147, SM00874): tRNA synthetase B5 domain
BU624867
28 GANinteractorBACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
BU624867
29 GEMIN7interactorGemin7 (PF11095, IPR020338): Gem-associated protein 7 (Gemin7)
SUZ-C (PF12901, IPR024642): SUZ-C motif
BU624867
30 HAUS1interactorTHP2 (PF09432, IPR018557): Tho complex subunit THP2
XhlA (PF10779, IPR019715): Haemolysin XhlA
DUF3496 (PF12001, IPR021885): Domain of unknown function (DUF3496)
BU624867
31 HSPA5oncoproteinHSP70 (PF00012, IPR013126): Hsp70 proteinBU624867
32 IGBP1interactorTAP42 (PF04177, IPR007304): TAP42-like familyBU624867
33 KCNJ12interactorIRK (PF01007, IPR016449): Inward rectifier potassium channel
IRK_N (PF08466, IPR013673): Inward rectifier potassium channel N-terminal
BU624867
34 KCNJ4interactorIRK (PF01007, IPR016449): Inward rectifier potassium channel
IRK_N (PF08466, IPR013673): Inward rectifier potassium channel N-terminal
BU624867
35 KIF15interactorBcr-Abl_Oligo (PF09036, IPR015123): Bcr-Abl oncoprotein oligomerisation domain
DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
SlyX (PF04102, IPR007236): SlyX
STE (PF02200, IPR003120, SM00424): STE like transcription factor
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
FlxA (PF14282, IPR025577): FlxA-like protein
HMMR_C (PF15908, IPR031794): Hyaluronan mediated motility receptor C-terminal
BU624867
36 LOC101929876interactorNABU624867
37 LPAR6interactor7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
MscS_TM (PF12794, IPR025692): Mechanosensitive ion channel inner membrane domain 1
BU624867
38 LRIF1interactorLRIF1 (PF15741, IPR026191): Ligand-dependent nuclear receptor-interacting factor 1BU624867
39 MAP1LC3BinteractorAtg8 (PF02991, IPR004241): Autophagy protein Atg8 ubiquitin likeBU624867
40 MAP3K5oncoproteinPkinase (PF00069, IPR000719): Protein kinase domain
DUF4071 (PF13281, IPR025136): Domain of unknown function (DUF4071)
BU624867
41 MARK2interactorDUF702 (PF05142, IPR007818): Domain of unknown function (DUF702)
KA1 (PF02149, IPR001772): Kinase associated domain 1
Pkinase (PF00069, IPR000719): Protein kinase domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
BU624867
42 MCM2oncoproteinAAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
BU624867
43 MGMTinteractorDNA_binding_1 (PF01035, IPR014048): 6-O-methylguanine DNA methyltransferase, DNA binding domain
Methyltransf_1N (PF02870, IPR008332): 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain
BU624867
44 MPC2interactorMPC (PF03650, IPR005336): Uncharacterised protein family (UPF0041)BU624867
45 MRPS35interactorMRP-S28 (PF10213, IPR019349): Mitochondrial ribosomal subunit proteinBU624867
46 NEDD4suppressorRota_NS26 (PF01525, IPR002512): Rotavirus NS26
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
BU624867
47 NEDD8interactorubiquitin (PF00240, IPR000626, SM00213): Ubiquitin familyBU624867
48 NFX1interactorR3H (PF01424, IPR001374, SM00393): R3H domain
XPG_I (PF00867, IPR006086, SM00484): XPG I-region
zf-NF-X1 (PF01422, IPR000967, SM00438): NF-X1 type zinc finger
BU624867
49 NOS1interactorFAD_binding_1 (PF00667, IPR003097): FAD binding domain
Flavodoxin_1 (PF00258, IPR008254): Flavodoxin
NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain
NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
BU624867
50 NUDT21interactorNUDIX_2 (PF13869, IPR016706): Nucleotide hydrolaseBU624867
51 NUDT3interactorNUDIX (PF00293, IPR000086): NUDIX domainBU624867
52 NUP58interactorNucleoporin_FG2 (PF15967): Nucleoporin FG repeated regionBU624867
53 PTNoncoproteinPTN_MK_C (PF01091, IPR020090): PTN/MK heparin-binding protein family, C-terminal domain
PTN_MK_N (PF05196, IPR020089): PTN/MK heparin-binding protein family, N-terminal domain
BU624867
54 PTRFinteractorPTRF_SDPR (PF15237, IPR026752): PTRF/SDPR familyBU624867
55 RCHY1suppressorC1_2 (PF03107, IPR004146): C1 domain
zf-CHY (PF05495, IPR008913): CHY zinc finger
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
zinc_ribbon_6 (PF14599): Zinc-ribbon
BU624867
56 RNF2interactorzf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
BU624867
57 RPL10suppressorRibosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10eBU624867
58 RPL10AinteractorRibosomal_L1 (PF00687, IPR028364): Ribosomal protein L1p/L10e familyBU624867
59 RPL11suppressorRibosomal_L5 (PF00281, IPR002132): Ribosomal protein L5
Ribosomal_L5_C (PF00673, IPR002132): ribosomal L5P family C-terminus
BU624867
60 RPL13interactorRibosomal_L13e (PF01294, IPR001380): Ribosomal protein L13eBU624867
61 RPL14interactorKOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14
UPF0688 (PF15772, IPR031530): UPF0688 family
BU624867
62 RPL15interactorRibosomal_L15e (PF00827, IPR000439): Ribosomal L15BU624867
63 RPL18interactorRibosomal_L18 (PF17135): Ribosomal protein 60S L18 and 50S L18eBU624867
64 RPL18AinteractorRibosomal_L18A (PF01775, IPR023573): Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18ABU624867
65 RPL19interactorDUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682)
Ribosomal_L19e (PF01280, IPR000196): Ribosomal protein L19e
BU624867
66 RPL21interactorRibosomal_L21e (PF01157, IPR001147): Ribosomal protein L21eBU624867
67 RPL23interactorRibosomal_L14 (PF00238, IPR000218): Ribosomal protein L14p/L23eBU624867
68 RPL23AinteractorRibosomal_L23 (PF00276, IPR013025): Ribosomal protein L23
Ribosomal_L23eN (PF03939, IPR005633): Ribosomal protein L23, N-terminal domain
BU624867
69 RPL24interactorMAS20 (PF02064, IPR002056): MAS20 protein import receptor
Ribosomal_L24e (PF01246, IPR000988): Ribosomal protein L24e
BU624867
70 RPL27interactorRibosomal_L27e (PF01777, IPR001141): Ribosomal L27e protein familyBU624867
71 RPL27AinteractorRibosomal_L27A (PF00828, IPR021131): Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27ABU624867
72 RPL28interactorRibosomal_L28e (PF01778, IPR029004): Ribosomal L28e protein familyBU624867
73 RPL29interactorBRF1 (PF07741, IPR011665): Brf1-like TBP-binding domain
Ribosomal_L29e (PF01779, IPR002673): Ribosomal L29e protein family
BU624867
74 RPL3interactorRibosomal_L3 (PF00297, IPR000597): Ribosomal protein L3BU624867
75 RPL30interactorNCBP3 (PF10309, IPR019416): Nuclear cap-binding protein subunit 3BU624867
76 RPL31interactorRibosomal_L31e (PF01198, IPR000054): Ribosomal protein L31eBU624867
77 RPL36interactorRibosomal_L36e (PF01158, IPR000509): Ribosomal protein L36eBU624867
78 RPL37AinteractorRibosomal_L37ae (PF01780, IPR002674): Ribosomal L37ae protein familyBU624867
79 RPL38interactorRibosomal_L38e (PF01781, IPR002675): Ribosomal L38e protein familyBU624867
80 RPL4interactorRibosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family
Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain
BU624867
81 RPL5suppressorRibosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region
Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18
BU624867
82 RPL6interactorRibosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e
Ribosomal_L6e_N (PF03868, IPR005568): Ribosomal protein L6, N-terminal domain
BU624867
83 RPL7interactorRibosomal_L30 (PF00327, IPR016082): Ribosomal protein L30p/L7e
Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain
BU624867
84 RPL9interactorRibosomal_L6 (PF00347, IPR020040): Ribosomal protein L6BU624867
85 RPLP0interactorRibosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10
BU624867
86 RPLP0P6interactorNABU624867
87 RPLP1parental proteinRibosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal proteinBU624867
88 RPLP2interactorRibosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal proteinBU624867
89 RPS10interactorS10_plectin (PF03501, IPR005326): Plectin/S10 domainBU624867
90 RPS11interactorRibosomal_S17 (PF00366, IPR000266): Ribosomal protein S17
Ribosomal_S17_N (PF16205, IPR032440): Ribosomal_S17 N-terminal
BU624867
91 RPS13interactorRibosomal_S13_N (PF08069, IPR012606): Ribosomal S13/S15 N-terminal domain
Ribosomal_S15 (PF00312, IPR000589): Ribosomal protein S15
BU624867
92 RPS14interactorRibosomal_S11 (PF00411, IPR001971): Ribosomal protein S11BU624867
93 RPS15interactorRibosomal_S19 (PF00203, IPR002222): Ribosomal protein S19
Prok_Ub (PF14454, IPR032866): Prokaryotic Ubiquitin
BU624867
94 RPS15AinteractorRibosomal_S8 (PF00410, IPR000630): Ribosomal protein S8BU624867
95 RPS16interactorRibosomal_S9 (PF00380, IPR000754): Ribosomal protein S9/S16BU624867
96 RPS17interactorRibosomal_S17e (PF00833, IPR001210): Ribosomal S17BU624867
97 RPS19interactorRibosomal_S19e (PF01090, IPR001266): Ribosomal protein S19eBU624867
98 RPS2interactorRibosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain
Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain
BU624867
99 RPS20interactorRibosomal_S10 (PF00338, IPR027486): Ribosomal protein S10p/S20eBU624867
100 RPS21interactorRibosomal_S21e (PF01249, IPR001931): Ribosomal protein S21eBU624867
101 RPS23interactorRibosom_S12_S23 (PF00164, IPR006032): Ribosomal protein S12/S23BU624867
102 RPS24interactorFascin (PF06268, IPR022768): Fascin domain
Ribosomal_S24e (PF01282, IPR001976): Ribosomal protein S24e
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
BU624867
103 RPS25interactorRibosomal_S25 (PF03297, IPR004977): S25 ribosomal proteinBU624867
104 RPS26interactorRibosomal_S26e (PF01283, IPR000892): Ribosomal protein S26eBU624867
105 RPS27AinteractorDUF1049 (PF06305, IPR010445): Protein of unknown function (DUF1049)BU624867
106 RPS3interactorKH_2 (PF07650, IPR004044): KH domain
Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain
BU624867
107 RPS3AinteractorRibosomal_S3Ae (PF01015, IPR001593): Ribosomal S3Ae familyBU624867
108 RPS4XinteractorKOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_S4e (PF00900, IPR013845): Ribosomal family S4e
RS4NT (PF08071, IPR013843): RS4NT (NUC023) domain
S4 (PF01479, IPR002942, SM00363): S4 domain
40S_S4_C (PF16121, IPR032277): 40S ribosomal protein S4 C-terminus
BU624867
109 RPS5interactorRibosomal_S7 (PF00177, IPR023798): Ribosomal protein S7p/S5eBU624867
110 RPS6interactorRibosomal_S6e (PF01092, IPR001377): Ribosomal protein S6e
DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574)
BU624867
111 RPS7interactorRibosomal_S7e (PF01251, IPR000554): Ribosomal protein S7eBU624867
112 RPS8interactorRibosomal_S8e (PF01201, IPR022309): Ribosomal protein S8eBU624867
113 RPSAinteractorRibosomal_S2 (PF00318, IPR001865): Ribosomal protein S2
40S_SA_C (PF16122, IPR032281): 40S ribosomal protein SA C-terminus
BU624867
114 SNTA1interactorPDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
PH (PF00169, IPR001849, SM00233): PH domain
BU624867
115 SNTB1interactorGATA-N (PF05349, IPR008013): GATA-type transcription activator, N-terminal
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
PH (PF00169, IPR001849, SM00233): PH domain
BU624867
116 SNTB2interactorPDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
PH (PF00169, IPR001849, SM00233): PH domain
BU624867
117 TERF1interactorTRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
BU624867
118 TERF2interactorAconitase_C (PF00694, IPR000573): Aconitase C-terminal domain
TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
TERF2_RBM (PF16772, IPR031902): Telomeric repeat-binding factor 2 Rap1-binding motif
BU624867
119 TPT1interactorTCTP (PF00838, IPR018105): Translationally controlled tumour proteinBU624867
120 TRAF3IP1interactorMIP-T3 (PF10243): Microtubule-binding protein MIP-T3BU624867
121 UBE2D3interactorUQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzymeBU624867
122 UBL4Ainteractorubiquitin (PF00240, IPR000626, SM00213): Ubiquitin familyBU624867
123 XPO1interactorCRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
BU624867
124 XRCC6oncoproteinKu (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
SAP (PF02037, IPR003034, SM00513): SAP domain
BU624867

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