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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)98
The number (and %) of the onco-proteins15 (15.31 %)
The number (and %) of the tumor suppressors11 (11.22 %)
Total number of binary PPIs (saturation %)947 (19.92 %)
The number (and %) of affected PPIs98 (10.35 %)
The number of possible different fusions7
PPI diameter2
PPI radius1
The average degree of PPI18.796
Assortativity coefficient-0.1339
The network average Clustering coefficient0.492
The number (and %) of a zero Clustering coefficients4 (4.08 %)
The number (and %) of a zero Betweenness Centrality5 (5.10 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: DKC1 All fusions
: DL057785; DL058023;
Proteins found in more fusions EEF1G (see 1 fusions); CUL7 (see 2 fusions); HNRNPD (see 1 fusions); DKC1 (see 2 fusions); CSNK2A1 (see 1 fusions); SUZ12 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 DKC1parental protein980.1773896.234DKCLD (PF08068, IPR012960, SM01136): DKCLD (NUC011) domain
PUA (PF01472, IPR002478, SM00359): PUA domain
RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5
TruB_N (PF01509, IPR002501): TruB family pseudouridylate synthase (N terminal domain)
TruB_C_2 (PF16198, IPR032819): tRNA pseudouridylate synthase B C-terminal domain
2 ABCE1interactor100.5009.514ABC_tran (PF00005, IPR003439): ABC transporter
Fer4 (PF00037, IPR001450): 4Fe-4S binding domain
RLI (PF04068, IPR007209): Possible Fer4-like domain in RNase L inhibitor, RLI
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Fer4_7 (PF12838, IPR001450): 4Fe-4S dicluster domain
AAA_29 (PF13555): P-loop containing region of AAA domain
3 ABCF2interactor100.5116.433ABC_tran (PF00005, IPR003439): ABC transporter
VIT1 (PF01988, IPR008217): VIT family
Rop (PF01815, IPR000769): Rop protein
ABC_tran_Xtn (PF12848, IPR032781): ABC transporter
AAA_21 (PF13304, IPR003959): AAA domain, putative AbiEii toxin, Type IV TA system
4 ARRB1interactor80.5364.223Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
5 ARRB2interactor180.34045.246Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
6 BCCIPinteractor60.8670.495DNA_pol_phi (PF04931, IPR007015): DNA polymerase phi
BCIP (PF13862, IPR025602): p21-C-terminal region-binding protein
7 BMI1oncoprotein140.50015.334zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
8 CAND1interactor380.333168.813Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981)
HEAT (PF02985, IPR000357): HEAT repeat
TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20)
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
9 CSNK2A1oncoprotein260.287117.863Pkinase (PF00069, IPR000719): Protein kinase domain
10 CUL7protein found in more fusions320.43459.016ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
11 DAXXoncoprotein80.5715.269Daxx (PF03344, IPR005012): Daxx N-terminal Rassf1C-interacting domain
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Nop14 (PF04147, IPR007276): Nop14-like family
RF-1 (PF00472, IPR000352): RF-1 domain
Vpu (PF00558, IPR008187): Vpu protein
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
12 DCAF4interactor100WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
DUF4221 (PF13970, IPR025316): Domain of unknown function (DUF4221)
13 DDX18interactor380.469117.337DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
NPR3 (PF03666, IPR005365): Nitrogen Permease regulator of amino acid transport activity 3
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF4217 (PF13959, IPR025313, SM01178): Domain of unknown function (DUF4217)
14 DDX24interactor390.445127.990DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
Sec62 (PF03839, IPR004728): Translocation protein Sec62
Tti2 (PF10521, IPR018870): Tti2 family
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
15 DDX27interactor280.48951.342Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
MAP17 (PF15807, IPR031627): Membrane-associated protein 117 kDa, PDZK1-interacting protein 1
16 DDX31interactor110.5823.905DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Strep_SA_rep (PF06696, IPR009578): Streptococcal surface antigen repeat
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF4217 (PF13959, IPR025313, SM01178): Domain of unknown function (DUF4217)
17 DDX56interactor290.58433.230DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
18 DHX15interactor230.47447.924DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
AAA_29 (PF13555): P-loop containing region of AAA domain
19 DIMT1interactor21.0000RrnaAD (PF00398, IPR001737, SM00650): Ribosomal RNA adenine dimethylase
20 EEDsuppressor340.42080.821WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
21 EEF1Gprotein found in more fusions80.6190.644EF1G (PF00647, IPR001662): Elongation factor 1 gamma, conserved domain
GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain
GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain
SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein
22 EIF3Fsuppressor60.7331.571JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
23 EIF5Binteractor110.49110.661GAGA_bind (PF06217, IPR010409): GAGA binding protein-like family
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
MIase (PF02426, IPR026029): Muconolactone delta-isomerase
NOA36 (PF06524, IPR010531): NOA36 protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
IF-2 (PF11987, IPR023115): Translation-initiation factor 2
DUF3807 (PF12720, IPR024526): Protein of unknown function (DUF3807)
GTP_EFTU_D4 (PF14578, IPR029459): Elongation factor Tu domain 4
DUF4632 (PF15451, IPR027952): Domain of unknown function (DUF4632)
Coilin_N (PF15862, IPR031722): Coilin N-terminus
DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820)
24 ENDOGinteractor100Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
25 EPB41L3suppressor70.4764.8824_1_CTD (PF05902, IPR008379): 4.1 protein C-terminal domain (CTD)
FA (PF08736, IPR014847): FERM adjacent (FA)
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
SAB (PF04382, IPR007477): SAB domain
26 ERGoncoprotein30.6670.222Ets (PF00178, IPR000418, SM00413): Ets-domain
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
27 ESR1suppressor280.34566.302Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
28 FBLinteractor410.420186.970Fibrillarin (PF01269, IPR000692): Fibrillarin
29 FBXW11interactor110.3339.898WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
30 FTSJ3interactor320.52055.081DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
FtsJ (PF01728, IPR002877): FtsJ-like methyltransferase
M16C_assoc (PF08367, IPR013578): Peptidase M16C associated
Orthopox_F8 (PF05886, IPR008726): Orthopoxvirus F8 protein
Spb1_C (PF07780, IPR012920): Spb1 C-terminal domain
DUF3381 (PF11861, IPR024576): Domain of unknown function (DUF3381)
RRP14 (PF15459, IPR029188): 60S ribosome biogenesis protein Rrp14
31 GAR1interactor140.29740.992Gar1 (PF04410, IPR007504): Gar1/Naf1 RNA binding region
32 GNL2interactor160.48311.697DUF258 (PF03193, IPR004881): Protein of unknown function, DUF258
MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase
NGP1NT (PF08153, IPR012971): NGP1NT (NUC091) domain
SDA1 (PF05285, IPR007949): SDA1
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
33 GNL3interactor250.62024.486GN3L_Grn1 (PF08701, IPR014813): GNL3L/Grn1 putative GTPase
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
FAM176 (PF14851): FAM176 family
34 GTPBP4suppressor330.51367.717DUF258 (PF03193, IPR004881): Protein of unknown function, DUF258
MRC1 (PF09444, IPR018564): MRC1-like domain
NOG1 (PF06858, IPR010674): Nucleolar GTP-binding protein 1 (NOG1)
NOGCT (PF08155, IPR012973): NOGCT (NUC087) domain
Lip_prot_lig_C (PF10437, IPR019491): Bacterial lipoate protein ligase C-terminus
AAA_16 (PF13191): AAA ATPase domain
35 HDAC11interactor90.5838.188Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
36 HIST1H1Ainteractor190.42130.555Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
37 HNRNPDoncoprotein180.30153.229CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Keratin_2_head (PF16208, IPR032444): Keratin type II head
38 IFI16suppressor250.46743.550HIN (PF02760, IPR004021): HIN-200/IF120x domain
PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain
Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
39 KRR1interactor300.45172.090Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
KH_1 (PF00013, IPR004088, SM00322): KH domain
40 LIN28Ainteractor90.4175.726CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain
zf-CCHC (PF00098, IPR001878): Zinc knuckle
zf-CCHC_6 (PF15288): Zinc knuckle
41 LSM2interactor100LSM (PF01423, IPR001163): LSM domain
42 LYPLA2interactor100Abhydrolase_2 (PF02230, IPR003140): Phospholipase/Carboxylesterase
43 MAPK6oncoprotein40.6671.000Pkinase (PF00069, IPR000719): Protein kinase domain
44 MOV10interactor190.46232.176AAA_12 (PF13087): AAA domain
AAA_30 (PF13604): AAA domain
45 MPHOSPH10interactor150.7713.492Mpp10 (PF04006, IPR007151): Mpp10 protein
46 MPP1oncoprotein30.6671.000PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
SH3_2 (PF07653, IPR011511): Variant SH3 domain
Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
P33MONOX (PF15302, IPR026759): P33 mono-oxygenase
47 NAF1interactor110.43619.931AF-4 (PF05110, IPR007797): AF-4 proto-oncoprotein
Gar1 (PF04410, IPR007504): Gar1/Naf1 RNA binding region
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
48 NASPinteractor40.6671.067Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
SlyX (PF04102, IPR007236): SlyX
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TraV (PF09676, IPR014118): Type IV conjugative transfer system lipoprotein (TraV)
SHNi-TPR (PF10516, IPR019544): SHNi-TPR
XhlA (PF10779, IPR019715): Haemolysin XhlA
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
CCSAP (PF15748, IPR029774): Centriole, cilia and spindle-associated
MAP17 (PF15807, IPR031627): Membrane-associated protein 117 kDa, PDZK1-interacting protein 1
49 NHP2interactor190.29266.477Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
50 NIFKinteractor340.55156.338RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
hNIFK_binding (PF12196, IPR021043): FHA Ki67 binding domain of hNIFK
51 NMD3interactor60.6671.347DUF1816 (PF08846, IPR014945): Domain of unknown function (DUF1816)
NMD3 (PF04981, IPR007064): NMD3 family
HGTP_anticodon2 (PF12745, IPR024435): Anticodon binding domain of tRNAs
52 NOC2Linteractor270.62126.404CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
DNA_pol_phi (PF04931, IPR007015): DNA polymerase phi
Noc2 (PF03715, IPR005343): Noc2p family
CEND1 (PF15677, IPR020162): Cell cycle exit and neuronal differentiation protein 1
53 NOC4Linteractor90.6671.930CBF (PF03914, IPR005612, SM00521): CBF/Mak21 family
54 NOL12interactor160.60010.459DUF2357 (PF09823, IPR018633): Domain of unknown function (DUF2357)
Nop25 (PF09805, IPR019186): Nucleolar protein 12 (25kDa)
55 NOP10interactor120.28827.611Nop10p (PF04135, IPR007264): Nucleolar RNA-binding protein, Nop10p family
56 NOP2interactor400.471118.400BSP_II (PF05432, IPR008412): Bone sialoprotein II (BSP-II)
Methyltr_RsmB-F (PF01189, IPR001678): 16S rRNA methyltransferase RsmB/F
P120R (PF08062, IPR012586): P120R (NUC006) repeat
Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
DUF2477 (PF10631, IPR018904): Protein of unknown function (DUF2477)
FAM176 (PF14851): FAM176 family
Methyltr_RsmF_N (PF17125, IPR031341): N-terminal domain of 16S rRNA methyltransferase RsmF
57 NOP56interactor420.444158.135Cytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region
Nop (PF01798, IPR002687): snoRNA binding domain, fibrillarin
NOP5NT (PF08156, IPR012974): NOP5NT (NUC127) domain
RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
58 NOP58interactor380.479105.763Cellulose_synt (PF03552, IPR005150): Cellulose synthase
Nop (PF01798, IPR002687): snoRNA binding domain, fibrillarin
NOP5NT (PF08156, IPR012974): NOP5NT (NUC127) domain
Selenoprotein_S (PF06936, IPR009703): Selenoprotein S (SelS)
59 NTRK1oncoprotein470.272354.435I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
60 NXF1interactor240.42344.379NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
61 OBSL1interactor410.382134.007BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
62 PAXIP1interactor100.44412.428BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase
SURF6 (PF04935, IPR007019): Surfeit locus protein 6
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
PTCB-BRCT (PF12738, IPR001357): twin BRCT domain
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
LIG3_BRCT (PF16759, IPR031916): DNA ligase 3 BRCT domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
63 PES1interactor340.51169.242Pescadillo_N (PF06732, IPR010613): Pescadillo N-terminus
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
DUF3347 (PF11827, IPR021782): Protein of unknown function (DUF3347)
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
64 POLR1Cinteractor140.40726.480RNA_pol_A_bac (PF01000, IPR011262): RNA polymerase Rpb3/RpoA insert domain
65 PRR11interactor160.55811.890CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
PRIMA1 (PF16101): Proline-rich membrane anchor 1
66 PTGES3interactor80.38110.100CS (PF04969, IPR007052): CS domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
67 PUM3interactor360.54462.057CPL (PF08144, IPR012959): CPL (NUC119) domain
68 RBM28interactor200.46324.277CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27
DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Nop25 (PF09805, IPR019186): Nucleolar protein 12 (25kDa)
RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
Phage_TAC_13 (PF16459, IPR024410): Phage tail assembly chaperone, TAC
69 RNF2interactor390.378137.743zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
70 RPF2interactor250.60022.016Brix (PF04427, IPR007109, SM00879): Brix domain
71 RPL14interactor310.50869.531KOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14
UPF0688 (PF15772, IPR031530): UPF0688 family
72 RPL8interactor260.54534.514Ribosomal_L2 (PF00181, IPR022666): Ribosomal Proteins L2, RNA binding domain
Ribosomal_L2_C (PF03947, IPR022669): Ribosomal Proteins L2, C-terminal domain
73 RPLP0P6interactor110.6912.980NA
74 RPS4Xinteractor260.55734.067KOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_S4e (PF00900, IPR013845): Ribosomal family S4e
RS4NT (PF08071, IPR013843): RS4NT (NUC023) domain
S4 (PF01479, IPR002942, SM00363): S4 domain
40S_S4_C (PF16121, IPR032277): 40S ribosomal protein S4 C-terminus
75 RPS8interactor290.51559.554Ribosomal_S8e (PF01201, IPR022309): Ribosomal protein S8e
76 RPSAinteractor210.43844.978Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2
40S_SA_C (PF16122, IPR032281): 40S ribosomal protein SA C-terminus
77 RUVBL1oncoprotein170.44224.039TIP49 (PF06068, IPR010339): TIP49 C-terminus
78 RUVBL2oncoprotein180.52225.171TIP49 (PF06068, IPR010339): TIP49 C-terminus
79 SFNsuppressor120.5096.98114-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
80 SHMT2interactor130.43615.485SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase
81 SHQ1suppressor60.6001.471SHQ1 (PF04925, IPR007009): SHQ1 protein
82 SNU13interactor250.50735.676Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
83 SRP14interactor120.5767.997SRP14 (PF02290, IPR003210): Signal recognition particle 14kD protein
84 SSR1interactor50.6001.836TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
85 SUZ12suppressor190.51023.228DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070)
VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein
86 SYNCRIPinteractor160.45817.814RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Limkain-b1 (PF11608, IPR024582): Limkain b1
87 TBL3interactor210.70513.254SdiA-regulated (PF06977, IPR009722): SdiA-regulated
Utp13 (PF08625, IPR013934): Utp13 specific WD40 associated domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
WD40_like (PF17005, IPR031544): WD40-like domain
88 TERCinteractor60.6002.650NA
89 TERF2interactor70.5333.439Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain
TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
TERF2_RBM (PF16772, IPR031902): Telomeric repeat-binding factor 2 Rap1-binding motif
90 TERToncoprotein60.5335.167RVT_1 (PF00078, IPR000477): Reverse transcriptase (RNA-dependent DNA polymerase)
Telomerase_RBD (PF12009, IPR021891, SM00975): Telomerase ribonucleoprotein complex - RNA binding domain
91 UQCRC2oncoprotein40.8330.500Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
92 UTP14Ainteractor220.52439.133Utp14 (PF04615, IPR006709): Utp14 protein
93 WDR36interactor240.54736.063Utp21 (PF04192, IPR007319): Utp21 specific WD40 associated putative domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
WD40_like (PF17005, IPR031544): WD40-like domain
94 WDR48suppressor90.47210.755WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF3337 (PF11816, IPR021772): Domain of unknown function (DUF3337)
95 WRAP53oncoprotein30.6671.000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
96 WWOXsuppressor40.8330.182adh_short (PF00106, IPR002198): short chain dehydrogenase
WW (PF00397, IPR001202, SM00456): WW domain
97 XPO1interactor270.342105.074CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
98 ZC3H3interactor140.46215.426zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
CCDC24 (PF15669, IPR031367): Coiled-coil domain-containing protein 24 family

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