Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins DDB1 (from a repository: Sat Nov 19 13:08:35 2016)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 241 The number (and %) of the onco-proteins 65 (26.97 %) The number (and %) of the tumor suppressors 41 (17.01 %) Total number of binary PPIs (saturation %) 2053 (7.10 %) The number (and %) of affected PPIs 241 (11.74 %) The number of possible different fusions 38 PPI diameter 2 PPI radius 1 The average degree of PPI 16.290 Assortativity coefficient -0.2299 The network average Clustering coefficient 0.530 The number (and %) of a zero Clustering coefficients 3 (1.24 %) The number (and %) of a zero Betweenness Centrality 29 (12.03 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: DDB1	All fusions : BF976559; BF976636;
Proteins found in more fusions	GRK5 (see 3 fusions); DCAF1 (see 1 fusions); CUL1 (see 3 fusions); UBA1 (see 2 fusions); TPM2 (see 1 fusions); EWSR1 (see 2 fusions); HDAC5 (see 1 fusions); EP300 (see 1 fusions); PCNA (see 1 fusions); RPA1 (see 1 fusions); STAT1 (see 1 fusions); SNW1 (see 1 fusions); TRAF6 (see 1 fusions); CUL4A (see 4 fusions); HUWE1 (see 2 fusions); NF2 (see 1 fusions); TOPBP1 (see 2 fusions); RANBP9 (see 2 fusions); POLR2A (see 2 fusions); SHC1 (see 1 fusions); DDB1 (see 2 fusions); MIB1 (see 3 fusions); CUL7 (see 2 fusions); CUL3 (see 1 fusions); MYC (see 1 fusions); COPS5 (see 1 fusions); UBC (see 1 fusions); MTOR (see 1 fusions); TP53 (see 3 fusions); RTN4 (see 11 fusions); CRY2 (see 3 fusions); AHR (see 1 fusions); PUF60 (see 2 fusions); NCOA5 (see 1 fusions); UBR5 (see 4 fusions); NTRK1/TPR (see 1 fusions); RPTOR (see 3 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	DDB1	parental protein	241	0.060	35209.222	CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
2	ABL1	oncoprotein	17	0.383	32.750	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding SH3_1 (PF00018, IPR001452, SM00326): SH3 domain FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2
3	ACAT1	interactor	12	0.491	9.018	Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain Thiolase_N (PF00108, IPR020616): Thiolase, N-terminal domain
4	ACTR5	interactor	3	0.667	1.000	Actin (PF00022, IPR004000, SM00268): Actin DUF1542 (PF07564, IPR011439): Domain of Unknown Function (DUF1542) UPF0449 (PF15136, IPR028227): Uncharacterised protein family UPF0449
5	AHR	suppressor	6	0.700	1.134	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold PAS_4 (PF08448, IPR013656): PAS fold
6	ALB	interactor	3	0.667	0.333	Serum_albumin (PF00273, IPR014760, SM00103): Serum albumin family
7	AMBRA1	interactor	15	0.419	30.535	Acyl_CoA_thio (PF02551, IPR025652): Acyl-CoA thioesterase eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Spt20 (PF12090, IPR021950): Spt20 family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
8	APEX1	interactor	16	0.383	34.924	Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
9	ARID4B	interactor	10	0.889	1.344	ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain CDC45 (PF02724, IPR003874): CDC45-like protein DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) E7 (PF00527, IPR000148): E7 protein, Early protein NOA36 (PF06524, IPR010531): NOA36 protein PWWP (PF00855, IPR000313, SM00293): PWWP domain RBB1NT (PF08169, IPR012603): RBB1NT (NUC162) domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
10	ASB4	interactor	4	1.000	0	Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) SOCS_box (PF07525, IPR001496): SOCS box
11	ATP6V1F	interactor	6	0.467	5.400	ATP-synt_F (PF01990, IPR008218): ATP synthase (F/14-kDa) subunit
12	AURKA	oncoprotein	18	0.294	53.082	Pkinase (PF00069, IPR000719): Protein kinase domain MTBP_C (PF14920, IPR029418): MDM2-binding
13	AURKB	interactor	19	0.327	43.105	Pkinase (PF00069, IPR000719): Protein kinase domain
14	BANF1	interactor	12	0.509	11.464	BAF (PF02961, IPR004122, SM01023): Barrier to autointegration factor
15	BCOR	oncoprotein	8	0.429	7.098	Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) BCOR (PF15808, IPR031628): BCL-6 co-repressor, non-ankyrin-repeat region PUFD (PF16553, IPR032365): BCORL-PCGF1-binding domain
16	BECN1	suppressor	6	0.800	0.800	APG6 (PF04111, IPR007243): Autophagy protein Apg6 Ima1_N (PF09779, IPR018617): Ima1 N-terminal domain BH3 (PF15285, IPR029318): Beclin-1 BH3 domain, Bcl-2-interacting
17	BRCA1	suppressor	46	0.176	520.157	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
18	BRWD1	interactor	5	0.900	0.167	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain SEEEED (PF14797, IPR029394): Serine-rich region of AP3B1, clathrin-adaptor complex
19	BTRC	oncoprotein	26	0.370	83.280	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like
20	CAMKK1	interactor	1	0	0	Pkinase (PF00069, IPR000719): Protein kinase domain
21	CAND1	interactor	35	0.335	148.977	Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
22	CDC5L	interactor	36	0.225	239.637	OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
23	CDKN1A	suppressor	22	0.346	56.285	CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
24	CDKN1B	suppressor	16	0.433	29.101	CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor Multi-haem_cyto (PF13447): Seven times multi-haem cytochrome CxxCH
25	CDT1	oncoprotein	14	0.484	14.938	CDT1 (PF08839, IPR014939, SM01075): DNA replication factor CDT1 like CDT1_C (PF16679, IPR032054): DNA replication factor Cdt1 C-terminal domain
26	CENPA	interactor	10	0.417	8.450	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
27	CEP250	interactor	13	0.295	26.381	ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1 DivIC (PF04977, IPR007060): Septum formation initiator DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) EHN (PF06441, IPR010497): Epoxide hydrolase N terminus ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain SlyX (PF04102, IPR007236): SlyX Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal TSC22 (PF01166, IPR000580): TSC-22/dip/bun family CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Endonuc_Holl (PF10107, IPR019287): Endonuclease related to archaeal Holliday junction resolvase DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570) DGF-1_C (PF11040, IPR021053): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472) Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
28	CEP57	interactor	5	0.400	2.436	Cep57_MT_bd (PF06657, IPR024957): Centrosome microtubule-binding domain of Cep57 Tup_N (PF08581, IPR013890): Tup N-terminal CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57 TRIQK (PF15168, IPR024842): Triple QxxK/R motif-containing protein family
29	CEP72	interactor	3	0.667	0.667	LRR_9 (PF14580): Leucine-rich repeat FAM76 (PF16046, IPR032017): FAM76 protein
30	CGGBP1	interactor	3	1.000	0	AKAP95 (PF04988, IPR007071): A-kinase anchoring protein 95 (AKAP95) Mei5 (PF10376, IPR018468): Double-strand recombination repair protein
31	CHEK1	suppressor	13	0.500	12.837	Pkinase (PF00069, IPR000719): Protein kinase domain
32	CLCN1	interactor	4	1.000	0	CBS (PF00571, IPR000644, SM00116): CBS domain Voltage_CLC (PF00654, IPR001807): Voltage gated chloride channel
33	CLIC1	interactor	6	0.533	2.952	GST_N_2 (PF13409, IPR004045): Glutathione S-transferase, N-terminal domain GST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain
34	CLIC4	oncoprotein	4	0.833	0.667	GST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain GST_N_3 (PF13417, IPR004045): Glutathione S-transferase, N-terminal domain
35	CMAS	interactor	3	0.667	0.222	CTP_transf_3 (PF02348, IPR003329): Cytidylyltransferase Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
36	CNOT2	interactor	3	0.667	1.000	NOT2_3_5 (PF04153, IPR007282): NOT2 / NOT3 / NOT5 family
37	COPS2	suppressor	30	0.533	68.281	YozE_SAM_like (PF06855, IPR023089): YozE SAM-like fold TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat DUF2087 (PF09860, IPR018656): Uncharacterized protein conserved in bacteria (DUF2087) PCI (PF01399, IPR000717, SM00088): PCI domain TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
38	COPS3	interactor	34	0.535	69.892	RasGEF (PF00617, IPR001895, SM00147): RasGEF domain TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat PCI (PF01399, IPR000717, SM00088): PCI domain
39	COPS4	interactor	35	0.534	77.242	DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) PCI (PF01399, IPR000717, SM00088): PCI domain TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_14 (PF13428): Tetratricopeptide repeat
40	COPS5	protein found in more fusions	63	0.269	617.468	JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
41	COPS6	interactor	50	0.341	288.913	DUF320 (PF03777, IPR005528): Small secreted domain (DUF320) JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
42	COPS7A	interactor	29	0.626	54.754	PCI (PF01399, IPR000717, SM00088): PCI domain
43	COPS7B	interactor	21	0.867	3.833	PCI (PF01399, IPR000717, SM00088): PCI domain
44	COPS8	interactor	25	0.721	22.307	CSN8_PSD8_EIF3K (PF10075): CSN8/PSMD8/EIF3K family
45	CORO1B	interactor	8	0.250	19.667	DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899) Trimer_CC (PF08954, IPR015049, SM01167): Trimerisation motif WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_4 (PF16300): Type of WD40 repeat
46	CRBN	interactor	13	0.538	17.733	LON_substr_bdg (PF02190, IPR003111, SM00464): ATP-dependent protease La (LON) substrate-binding domain Yippee-Mis18 (PF03226, IPR004910): Yippee zinc-binding/DNA-binding /Mis18, centromere assembly
47	CRY2	protein found in more fusions	10	0.417	5.767	DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
48	CSTF2	interactor	6	0.800	0.582	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C (PF14304, IPR026896): Transcription termination and cleavage factor C-terminal CSTF2_hinge (PF14327, IPR025742): Hinge domain of cleavage stimulation factor subunit 2
49	CTNNB1	oncoprotein	28	0.233	139.884	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat
50	CUL1	suppressor	64	0.237	668.945	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
51	CUL3	protein found in more fusions	57	0.261	534.713	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
52	CUL4A	protein found in more fusions	102	0.139	2745.674	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
53	CUL4B	oncoprotein	71	0.222	1008.074	Cullin (PF00888, IPR001373, SM00182): Cullin family EBP50_C (PF09007, IPR015098): EBP50, C-terminal Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain MDFI (PF15316, IPR026134): MyoD family inhibitor
54	CUL5	suppressor	40	0.418	173.077	Cullin (PF00888, IPR001373, SM00182): Cullin family GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
55	CUL7	protein found in more fusions	38	0.210	274.490	ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
56	DCAF1	protein found in more fusions	51	0.212	651.537	DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) LisH (PF08513, IPR013720, SM00667): LisH ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
57	DCAF10	interactor	7	0.762	3.667	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
58	DCAF11	interactor	15	0.819	6.947	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
59	DCAF12	interactor	5	1.000	0	ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_like (PF17005, IPR031544): WD40-like domain
60	DCAF13	interactor	3	0.667	0.118	eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A Sof1 (PF04158, IPR007287): Sof1-like domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
61	DCAF15	interactor	4	0.667	1.167	DCAF15_WD40 (PF14939, IPR032734): DDB1-and CUL4-substrate receptor 15, WD repeat
62	DCAF16	interactor	6	1.000	0	DCA16 (PF15349, IPR028216): DDB1- and CUL4-associated factor 16
63	DCAF17	interactor	5	1.000	0	DCAF17 (PF15802, IPR031620): DDB1- and CUL4-associated factor 17
64	DCAF4	interactor	8	1.000	0	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain DUF4221 (PF13970, IPR025316): Domain of unknown function (DUF4221)
65	DCAF5	interactor	6	0.533	3.054	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2634 (PF10934, IPR020288): Protein of unknown function (DUF2634) IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
66	DCAF6	interactor	7	0.800	0.639	Herpes_pp85 (PF04637, IPR006731): Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF3408 (PF11888, IPR021823): Protein of unknown function (DUF3408) ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain ATAD4 (PF15321, IPR028237): ATPase family AAA domain containing 4 MRI (PF15325, IPR028278): Modulator of retrovirus infection WD40_like (PF17005, IPR031544): WD40-like domain
67	DCAF7	interactor	10	0.311	20.367	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
68	DCAF8	interactor	13	0.782	4.383	DUF1635 (PF07795, IPR012862): Protein of unknown function (DUF1635) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain DUF4661 (PF15576, IPR029073): Domain of unknown function (DUF4661)
69	DCLRE1C	interactor	5	0.500	1.208	DRMBL (PF07522, IPR011084): DNA repair metallo-beta-lactamase DUF3290 (PF11694, IPR021707): Protein of unknown function (DUF3290) Lactamase_B_2 (PF12706, IPR001279): Beta-lactamase superfamily domain
70	DCUN1D1	interactor	26	0.628	36.698	Cullin_binding (PF03556, IPR005176): Cullin binding UBA_4 (PF14555): UBA-like domain
71	DCUN1D5	interactor	8	0.964	0.057	Cullin_binding (PF03556, IPR005176): Cullin binding
72	DDA1	interactor	34	0.367	150.143	DDA1 (PF10172, IPR018276): Det1 complexing ubiquitin ligase
73	DDB2	suppressor	29	0.437	112.088	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
74	DDIT4	interactor	4	0.667	0.383	RTP801_C (PF07809, IPR012918): RTP801 C-terminal region
75	DET1	interactor	8	0.857	0.839	Det1 (PF09737, IPR019138): De-etiolated protein 1 Det1
76	DLC1	suppressor	5	1.000	0	RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) START (PF01852, IPR002913, SM00234): START domain DUF4561 (PF15120, IPR027818): Domain of unknown function (DUF4561)
77	DPPA4	interactor	11	0.489	9.773	Ribosomal_L40e (PF01020, IPR001975): Ribosomal L40e family DCR (PF14047, IPR025891): Dppa2/4 conserved region Dppa2_A (PF14049, IPR025892): Dppa2/4 conserved region in higher vertebrates
78	DTL	interactor	20	0.479	38.439	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
79	DYRK1B	oncoprotein	6	0.400	3.033	Pkinase (PF00069, IPR000719): Protein kinase domain
80	DYRK2	interactor	10	0.356	18.809	Pkinase (PF00069, IPR000719): Protein kinase domain
81	E2F1	suppressor	17	0.412	32.787	Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
82	EED	suppressor	35	0.198	245.012	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
83	EP300	oncoprotein	43	0.197	401.918	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
84	EPB41L3	suppressor	8	0.429	6.850	4_1_CTD (PF05902, IPR008379): 4.1 protein C-terminal domain (CTD) FA (PF08736, IPR014847): FERM adjacent (FA) FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 SAB (PF04382, IPR007477): SAB domain
85	ERCC6	oncoprotein	19	0.474	24.891	Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Spt5-NGN (PF03439, IPR005100): Early transcription elongation factor of RNA pol II, NGN section Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
86	ERCC8	oncoprotein	29	0.433	119.894	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain DUF4859 (PF16151, IPR032339): Domain of unknown function (DUF4859)
87	EWSR1	oncoprotein	40	0.283	268.992	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head
88	FAF2	interactor	14	0.423	27.694	DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682) UBX (PF00789, IPR001012, SM00166): UBX domain Thioredoxin_7 (PF13899): Thioredoxin-like UBA_4 (PF14555): UBA-like domain
89	FBXO44	interactor	9	0.639	5.674	FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like
90	FBXW5	interactor	6	0.800	1.667	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat F-box-like (PF12937, IPR001810): F-box-like
91	FBXW8	interactor	11	0.655	4.885	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like
92	FLNC	interactor	9	0.472	6.631	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Filamin (PF00630, IPR017868): Filamin/ABP280 repeat PapC_N (PF13954, IPR025885): PapC N-terminal domain
93	FTSJ3	interactor	14	0.473	15.108	DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) FtsJ (PF01728, IPR002877): FtsJ-like methyltransferase M16C_assoc (PF08367, IPR013578): Peptidase M16C associated Orthopox_F8 (PF05886, IPR008726): Orthopoxvirus F8 protein Spb1_C (PF07780, IPR012920): Spb1 C-terminal domain DUF3381 (PF11861, IPR024576): Domain of unknown function (DUF3381) RRP14 (PF15459, IPR029188): 60S ribosome biogenesis protein Rrp14
94	FZR1	suppressor	10	0.489	10.555	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
95	GNB2	interactor	9	0.472	8.755	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat CALM_bind (PF16025): Calcium-dependent calmodulin binding WD40_like (PF17005, IPR031544): WD40-like domain
96	GPN1	interactor	9	0.500	8.912	ATP_bind_1 (PF03029, IPR004130): Conserved hypothetical ATP binding protein NB-ARC (PF00931, IPR002182): NB-ARC domain
97	GPS1	interactor	28	0.545	57.656	RPN7 (PF10602, IPR019585): 26S proteasome subunit RPN7 PCI (PF01399, IPR000717, SM00088): PCI domain
98	GRK5	protein found in more fusions	16	0.410	30.003	Pkinase (PF00069, IPR000719): Protein kinase domain RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
99	GRK6	interactor	1	0	0	Pkinase (PF00069, IPR000719): Protein kinase domain RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
100	GRWD1	interactor	14	0.626	13.687	Voldacs (PF03517): Regulator of volume decrease after cellular swelling WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
101	HDAC1	suppressor	39	0.262	265.733	FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
102	HDAC2	suppressor	34	0.328	148.299	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
103	HDAC3	suppressor	17	0.258	48.443	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
104	HDAC5	protein found in more fusions	23	0.277	84.585	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
105	HDAC8	interactor	4	0.667	1.333	DNase-RNase (PF02577, IPR003729): Bifunctional nuclease Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
106	HIST1H1A	interactor	12	0.394	18.138	Mucin (PF01456, IPR000458): Mucin-like glycoprotein Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
107	HIST1H1C	oncoprotein	21	0.452	41.967	Amelin (PF05111, IPR007798, SM00817): Ameloblastin precursor (Amelin) Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family DUF4349 (PF14257, IPR025645): Domain of unknown function (DUF4349)
108	HIST1H3A	interactor	29	0.233	171.101	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
109	HOXB4	interactor	3	1.000	0	DUF4106 (PF13388, IPR025179): Protein of unknown function (DUF4106)
110	HOXD3	interactor	1	0	0	Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DUF4074 (PF13293, IPR025281): Domain of unknown function (DUF4074)
111	HUWE1	oncoprotein	35	0.225	230.390	BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
112	INO80	interactor	4	0.667	2.000	Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein RNA_pol_Rbc25 (PF08292, IPR013238): RNA polymerase III subunit Rpc25 SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain POTRA (PF07244, IPR010827): Surface antigen variable number repeat Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DBINO (PF13892, IPR020838): DNA-binding domain FAM176 (PF14851): FAM176 family MAP17 (PF15807, IPR031627): Membrane-associated protein 117 kDa, PDZK1-interacting protein 1
113	INVS	interactor	2	1.000	0	IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
114	IP6K1	interactor	5	0.900	0.095	IPK (PF03770, IPR005522): Inositol polyphosphate kinase SIN1 (PF05422, IPR008828): Stress-activated map kinase interacting protein 1 (SIN1)
115	KAT2A	interactor	13	0.424	17.816	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family
116	KATNA1	interactor	5	0.800	0.750	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) ABC_tran (PF00005, IPR003439): ABC transporter Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat AAA_22 (PF13401, IPR003593): AAA domain
117	KCND3	interactor	2	1.000	0	Ion_trans (PF00520, IPR005821): Ion transport protein BTB_2 (PF02214, IPR003131): BTB/POZ domain Shal-type (PF11601, IPR021645): Shal-type voltage-gated potassium channels, N-terminal DUF3399 (PF11879, IPR024587): Domain of unknown function (DUF3399)
118	KMT5A	interactor	7	0.571	3.415	ATP-synt_Eps (PF04627, IPR006721): Mitochondrial ATP synthase epsilon chain ERp29 (PF07749, IPR011679): Endoplasmic reticulum protein ERp29, C-terminal domain SET (PF00856, IPR001214, SM00317): SET domain
119	LASP1	oncoprotein	3	0.667	0.286	LIM (PF00412, IPR001781, SM00132): LIM domain Nebulin (PF00880, IPR000900, SM00227): Nebulin repeat SH3_9 (PF14604, IPR001452): Variant SH3 domain
120	LMO4	interactor	5	0.800	0.354	LIM (PF00412, IPR001781, SM00132): LIM domain zf-dskA_traR (PF01258, IPR000962): Prokaryotic dksA/traR C4-type zinc finger
121	LRWD1	interactor	7	0.667	1.343	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat
122	LSM2	interactor	2	1.000	0	LSM (PF01423, IPR001163): LSM domain
123	MAFB	oncoprotein	3	1.000	0	bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor Maf_N (PF08383, IPR013592): Maf N-terminal region
124	MBD3	interactor	15	0.319	42.956	DUF2201_N (PF13203, IPR025154): Putative metallopeptidase domain
125	MCM10	interactor	8	0.500	7.185	Mcm10 (PF09332, IPR015411): Mcm10 replication factor zf-primase (PF09329, IPR015408): Primase zinc finger AATF-Che1 (PF13339, IPR025160): Apoptosis antagonizing transcription factor
126	MCM5	oncoprotein	15	0.343	27.774	MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
127	MDM2	oncoprotein	35	0.262	213.344	Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
128	MEF2A	oncoprotein	6	0.667	1.510	TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat
129	MIB1	protein found in more fusions	6	0.800	0.556	Ank (PF00023, IPR002110, SM00248): Ankyrin repeat MIB_HERC2 (PF06701, IPR010606): Mib_herc2 ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
130	MTOR	oncoprotein	15	0.341	36.203	DUF1104 (PF06518, IPR009488): Protein of unknown function (DUF1104) EPSP_synthase (PF00275, IPR001986): EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats TPR_19 (PF14559): Tetratricopeptide repeat
131	MYB	oncoprotein	9	0.361	12.862	Cmyb_C (PF09316, IPR015395): C-myb, C-terminal LMSTEN (PF07988, IPR012642): LMSTEN motif Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
132	MYC	oncoprotein	34	0.235	225.408	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region
133	NANOG	interactor	13	0.333	19.476	Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
134	NCOA5	suppressor	5	0.833	0.182	Macoilin (PF09726, IPR019130): Transmembrane protein
135	NEDD8	interactor	31	0.522	87.640	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
136	NF2	suppressor	14	0.359	17.075	ERM (PF00769, IPR011259): Ezrin/radixin/moesin family FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain
137	NPHP4	interactor	2	1.000	0	Corona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein
138	NR1I2	suppressor	4	0.667	1.333	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
139	NR2C2	suppressor	9	0.536	5.927	Flagellin_N (PF00669, IPR001029): Bacterial flagellin N-terminal helical region zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
140	NTRK1	oncoprotein	64	0.158	1017.095	I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
141	NUMA1	oncoprotein	16	0.292	35.876	Colicin (PF01024, IPR000293): Colicin pore forming domain Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32 DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF848 (PF05852, IPR008566): Gammaherpesvirus protein of unknown function (DUF848) Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Tup_N (PF08581, IPR013890): Tup N-terminal CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
142	NUP133	oncoprotein	9	0.389	8.330	Nucleoporin_C (PF03177, IPR007187): Non-repetitive/WGA-negative nucleoporin C-terminal
143	NUP43	interactor	7	0.476	5.715	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
144	NXF1	interactor	45	0.152	516.364	NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat
145	OBSL1	interactor	30	0.234	137.169	BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
146	PCGF1	interactor	12	0.436	18.172	zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
147	PCNA	oncoprotein	38	0.272	231.274	PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain
148	PHIP	oncoprotein	11	0.455	9.536	DTHCT (PF08070, IPR012542): DTHCT (NUC029) region DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) E7 (PF00527, IPR000148): E7 protein, Early protein WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
149	PIDD1	interactor	2	1.000	0	Death (PF00531, IPR000488, SM00005): Death domain ZU5 (PF00791, IPR000906, SM00218): ZU5 domain Peptidase_S68 (PF10461, IPR019502): Peptidase S68 LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat
150	PIN1	suppressor	11	0.527	8.670	Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain WW (PF00397, IPR001202, SM00456): WW domain
151	PMS2	oncoprotein	6	0.667	1.285	DNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain MORN_2 (PF07661, IPR011652): MORN repeat variant MutL_C (PF08676, IPR014790, SM00853): MutL C terminal dimerisation domain HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
152	POLR2A	protein found in more fusions	30	0.273	135.135	RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
153	POLR2J	interactor	4	1.000	0	RNA_pol_L_2 (PF13656): RNA polymerase Rpb3/Rpb11 dimerisation domain
154	POU5F1	oncoprotein	20	0.234	74.452	Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
155	PSMA1	interactor	15	0.385	34.163	Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
156	PTEN	suppressor	8	0.464	6.136	DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
157	PTPN14	oncoprotein	6	0.533	1.808	FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
158	PUF60	protein found in more fusions	18	0.397	27.301	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Titin_Z (PF09042, IPR015129): Titin Z TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
159	PWP1	interactor	11	0.691	3.794	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
160	PYGO2	interactor	10	0.528	8.339	PHD (PF00628, IPR019787, SM00249): PHD-finger
161	RAD21	oncoprotein	20	0.363	40.253	Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
162	RAG1	interactor	8	0.667	3.029	zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-RAG1 (PF10426, IPR019485): Recombination-activating protein 1 zinc-finger domain RAG1_imp_bd (PF12560): RAG1 importin binding RAG1 (PF12940, IPR024627): Recombination-activation protein 1 (RAG1), recombinase
163	RAG2	interactor	4	0.667	0.722	RAG2 (PF03089, IPR004321): Recombination activating protein 2 RAG2_PHD (PF13341, IPR025162): RAG2 PHD domain
164	RANBP9	suppressor	13	0.409	23.863	Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator LisH (PF08513, IPR013720, SM00667): LisH SPRY (PF00622, IPR003877, SM00449): SPRY domain CLTH (PF10607, IPR024964): CTLH/CRA C-terminal to LisH motif domain
165	RASSF1	suppressor	10	0.583	3.916	RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) Nore1-SARAH (PF16517, IPR011524): Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain
166	RASSF10	suppressor	2	1.000	0	DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) FliJ (PF02050, IPR012823): Flagellar FliJ protein Mt_ATP-synt_B (PF05405, IPR008688): Mitochondrial ATP synthase B chain precursor (ATP-synt_B) PAP_RNA-bind (PF04926, IPR007010): Poly(A) polymerase predicted RNA binding domain RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
167	RASSF9	interactor	3	0.667	0.182	RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain Spore_III_AB (PF09548, IPR014198): Stage III sporulation protein AB (spore_III_AB) DUF3087 (PF11286, IPR021438): Protein of unknown function (DUF3087)
168	RBBP4	oncoprotein	33	0.269	206.156	eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
169	RBBP5	oncoprotein	13	0.394	21.258	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457) ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
170	RBBP7	suppressor	26	0.369	98.183	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
171	RBP1	suppressor	3	1.000	0	Lipocalin (PF00061, IPR000566): Lipocalin / cytosolic fatty-acid binding protein family
172	RBX1	oncoprotein	45	0.311	290.142	zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
173	RECQL	oncoprotein	6	0.467	2.200	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Lipoprotein_3 (PF00938, IPR001595): Lipoprotein RQC (PF09382, IPR018982, SM00956): RQC domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
174	RFWD2	suppressor	24	0.696	17.285	Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein IncA (PF04156, IPR007285): IncA protein WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) WD40_like (PF17005, IPR031544): WD40-like domain
175	RGS2	oncoprotein	3	1.000	0	RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
176	RICTOR	interactor	6	0.533	3.284	RasGEF_N_2 (PF14663, IPR029453): Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_N (PF14664, IPR028267): Rapamycin-insensitive companion of mTOR, N-term RICTOR_phospho (PF14665, IPR029259): Rapamycin-insensitive companion of mTOR, phosphorylation-site RICTOR_M (PF14666, IPR029451): Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V (PF14668, IPR029452): Rapamycin-insensitive companion of mTOR, domain 5
177	RORA	interactor	4	0.667	0.376	zf-C3HC (PF07967, IPR012935): C3HC zinc finger-like zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
178	RPA1	suppressor	34	0.282	189.617	Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
179	RPA2	oncoprotein	27	0.328	96.385	RPA_C (PF08784, IPR014892): Replication protein A C terminal tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
180	RPA3	interactor	21	0.416	38.361	Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
181	RPS6KB2	interactor	9	0.306	9.469	Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
182	RPS7	interactor	23	0.308	69.559	Ribosomal_S7e (PF01251, IPR000554): Ribosomal protein S7e
183	RPTOR	protein found in more fusions	12	0.418	14.305	HEAT (PF02985, IPR000357): HEAT repeat WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 (PF13646): HEAT repeats Raptor_N (PF14538, IPR029347): Raptor N-terminal CASPase like domain
184	RTN4	suppressor	9	0.500	5.535	CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain Reticulon (PF02453, IPR003388): Reticulon Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
185	SALL2	suppressor	7	0.619	2.360	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type MPP6 (PF10175, IPR019324): M-phase phosphoprotein 6 zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding Astro_capsid_p (PF12226, IPR022027): Turkey astrovirus capsid protein zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
186	SAMHD1	interactor	10	0.833	0.942	HD (PF01966, IPR006674): HD domain SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
187	SAP130	interactor	16	0.500	27.823	SAP130_C (PF16014, IPR031963): Histone deacetylase complex subunit SAP130 C-terminus
188	SAP30	interactor	12	0.682	12.085	Titin_Z (PF09042, IPR015129): Titin Z zf-SAP30 (PF13866, IPR025717): SAP30 zinc-finger SAP30_Sin3_bdg (PF13867, IPR025718): Sin3 binding region of histone deacetylase complex subunit SAP30
189	SAP30BP	interactor	10	0.311	12.843	Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HCNGP (PF07818, IPR012479): HCNGP-like protein Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
190	SF3A3	interactor	19	0.386	40.331	DUF3449 (PF11931, IPR024598): Domain of unknown function (DUF3449) SF3a60_bindingd (PF12108, IPR021966): Splicing factor SF3a60 binding domain Telomere_Sde2_2 (PF13297): Telomere stability C-terminal PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal SF3A3 (PF16837, IPR031774): Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9
191	SHC1	oncoprotein	7	0.533	3.520	PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) SH2 (PF00017, IPR000980, SM00252): SH2 domain
192	SIN3A	oncoprotein	23	0.372	74.415	Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein
193	SIRT6	suppressor	11	0.327	18.478	SIR2 (PF02146, IPR003000): Sir2 family TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
194	SIRT7	interactor	34	0.207	224.053	DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family
195	SKP2	suppressor	25	0.353	92.635	LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRR_2 (PF07723, IPR013101): Leucine Rich Repeat LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) F-box-like (PF12937, IPR001810): F-box-like LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat
196	SLX4	suppressor	7	0.476	5.535	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Slx4 (PF09494, IPR018574): Slx4 endonuclease zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
197	SNU13	interactor	11	0.378	13.444	Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
198	SNW1	protein found in more fusions	33	0.284	142.945	SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain
199	SNX2	interactor	5	0.700	1.119	PX (PF00787, IPR001683, SM00312): PX domain Sorting_nexin (PF03700, IPR005329): Sorting nexin, N-terminal domain Vps5 (PF09325, IPR015404): Vps5 C terminal like
200	SRSF9	interactor	12	0.515	9.290	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
201	STAT1	suppressor	14	0.346	24.630	SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain STAT1_TAZ2bind (PF12162, IPR022752): STAT1 TAZ2 binding domain
202	STRIP1	interactor	4	0.833	0.087	ELM2 (PF01448, IPR000949): ELM2 domain N1221 (PF07923, IPR012486): N1221-like protein DUF3402 (PF11882, IPR021819): Domain of unknown function (DUF3402)
203	STRN4	interactor	4	0.833	0.087	CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain Striatin (PF08232, IPR013258): Striatin family WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
204	SUDS3	interactor	10	1.000	0	Sds3 (PF08598, IPR013907): Sds3-like
205	SUPT3H	interactor	8	0.571	5.023	TFIID-18kDa (PF02269, IPR003195): Transcription initiation factor IID, 18kD subunit DUF4093 (PF13331, IPR025156): Domain of unknown function (DUF4093)
206	TADA2A	interactor	14	0.374	28.136	SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
207	TAF15	oncoprotein	25	0.343	74.493	API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5) GRP (PF07172, IPR010800): Glycine rich protein family Presenilin (PF01080, IPR001108): Presenilin RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
208	TCERG1	interactor	11	0.418	15.818	FF (PF01846, IPR002713, SM00441): FF domain WW (PF00397, IPR001202, SM00456): WW domain Folliculin (PF11704, IPR021713): Vesicle coat protein involved in Golgi to plasma membrane transport DUF3807 (PF12720, IPR024526): Protein of unknown function (DUF3807) DUF3886 (PF13025, IPR024980): Protein of unknown function (DUF3886) Spore_coat_CotO (PF14153, IPR025439): Spore coat protein CotO FAM150 (PF15129, IPR029364): FAM150 family
209	TERF1	interactor	17	0.250	58.723	TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
210	TERF2	interactor	12	0.527	10.944	Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain TERF2_RBM (PF16772, IPR031902): Telomeric repeat-binding factor 2 Rap1-binding motif
211	TERT	oncoprotein	8	0.571	6.428	RVT_1 (PF00078, IPR000477): Reverse transcriptase (RNA-dependent DNA polymerase) Telomerase_RBD (PF12009, IPR021891, SM00975): Telomerase ribonucleoprotein complex - RNA binding domain
212	TET1	oncoprotein	3	0.667	0.333	zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain Tet_JBP (PF12851, IPR024779): Oxygenase domain of the 2OGFeDO superfamily
213	TET2	suppressor	2	1.000	0	Tet_JBP (PF12851, IPR024779): Oxygenase domain of the 2OGFeDO superfamily
214	TET3	interactor	2	1.000	0	zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain Tet_JBP (PF12851, IPR024779): Oxygenase domain of the 2OGFeDO superfamily
215	TOPBP1	protein found in more fusions	12	0.327	17.513	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PTCB-BRCT (PF12738, IPR001357): twin BRCT domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
216	TOR1AIP2	interactor	10	0.889	0.615	LAP1C (PF05609, IPR008662): Lamina-associated polypeptide 1C (LAP1C)
217	TP53	suppressor	65	0.189	866.104	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
218	TP73	suppressor	15	0.516	15.269	P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
219	TPM2	protein found in more fusions	7	0.733	4.000	DASH_Spc19 (PF08287, IPR013251): Spc19 Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
220	TPR	oncoprotein	14	0.374	17.470	Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus ZapB (PF06005, IPR009252): Cell division protein ZapB Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 XhlA (PF10779, IPR019715): Haemolysin XhlA ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein DUF3373 (PF11853, IPR021803): Protein of unknown function (DUF3373) DUF4107 (PF13389, IPR025180): Protein of unknown function (DUF4107) JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
221	TRAF6	protein found in more fusions	12	0.436	20.061	SlyX (PF04102, IPR007236): SlyX zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
222	TRPC4AP	interactor	7	0.810	1.033	Put_DNA-bind_N (PF06971, IPR009718): Putative DNA-binding protein N-terminus DUF3689 (PF12463, IPR022162): Protein of unknown function (DUF3689)
223	TUBGCP2	interactor	10	0.467	13.116	Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family zf-Tim10_DDP (PF02953, IPR004217): Tim10/DDP family zinc finger
224	UBA1	protein found in more fusions	14	0.385	14.748	ThiF (PF00899, IPR000594): ThiF family E1_UFD (PF09358, IPR018965, SM00985): Ubiquitin fold domain UBA_e1_thiolCys (PF10585, IPR019572): Ubiquitin-activating enzyme active site
225	UBC	protein found in more fusions	63	0.185	890.191	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
226	UBE2E3	interactor	13	0.545	10.131	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
227	UBR5	protein found in more fusions	25	0.225	137.085	CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain SDA1 (PF05285, IPR007949): SDA1 HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain E3_UbLigase_EDD (PF11547, IPR024725): E3 ubiquitin ligase EDD PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
228	UBXN1	interactor	16	0.495	24.439	Selenoprotein_S (PF06936, IPR009703): Selenoprotein S (SelS) UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain UBX (PF00789, IPR001012, SM00166): UBX domain
229	UBXN7	interactor	17	0.500	29.342	UBX (PF00789, IPR001012, SM00166): UBX domain UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif Thioredoxin_7 (PF13899): Thioredoxin-like UBA_4 (PF14555): UBA-like domain
230	UCHL1	suppressor	13	0.474	14.639	Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1
231	UNG	interactor	7	0.619	2.983	UDG (PF03167, IPR005122, SM00986): Uracil DNA glycosylase superfamily
232	UVSSA	interactor	2	1.000	0	DUF2043 (PF09740, IPR018610): Uncharacterized conserved protein (DUF2043) DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
233	VASP	interactor	10	0.417	9.865	ASD2 (PF08687, IPR014799): Apx/Shroom domain ASD2 CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal VASP_tetra (PF08776, IPR014885): VASP tetramerisation domain WH1 (PF00568, IPR000697, SM00461): WH1 domain
234	VTN	interactor	6	0.600	1.597	Hemopexin (PF00045, IPR018487, SM00120): Hemopexin Somatomedin_B (PF01033, IPR001212, SM00201): Somatomedin B domain
235	WDTC1	interactor	5	0.600	1.784	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
236	WSB1	interactor	4	1.000	0	PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain SOCS_box (PF07525, IPR001496): SOCS box
237	WSB2	interactor	3	1.000	0	PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 SOCS_box (PF07525, IPR001496): SOCS box
238	XPA	oncoprotein	10	0.422	11.966	XPA_C (PF05181, IPR022656): XPA protein C-terminus XPA_N (PF01286, IPR022652): XPA protein N-terminal MscS_TM (PF12794, IPR025692): Mechanosensitive ion channel inner membrane domain 1 zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain
239	XPC	oncoprotein	12	0.379	17.685	Rad4 (PF03835, IPR018325): Rad4 transglutaminase-like domain BHD_1 (PF10403, IPR018326, SM01030): Rad4 beta-hairpin domain 1 BHD_2 (PF10404, IPR018327, SM01031): Rad4 beta-hairpin domain 2 BHD_3 (PF10405, IPR018328, SM01032): Rad4 beta-hairpin domain 3 Macoilin (PF09726, IPR019130): Transmembrane protein SOG2 (PF10428, IPR019487): RAM signalling pathway protein Abdominal-A (PF12407, IPR022132): Homeobox protein DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820)
240	YARS	interactor	3	0.667	0.087	tRNA-synt_1b (PF00579, IPR002305): tRNA synthetases class I (W and Y) tRNA_bind (PF01588, IPR002547): Putative tRNA binding domain
241	ZNF277	interactor	2	1.000	0	zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)

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