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Visible interactions: all affected independent (normal) missing (in fusions) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins DCTD (from a repository: Tue Feb 21 20:35:41 2017)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)12
The number (and %) of the onco-proteins2 (16.67 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)16 (24.24 %)
The number (and %) of affected PPIs12 (75.00 %)
The number of possible different fusions2
PPI diameter2
PPI radius1
The average degree of PPI2.000
Assortativity coefficient-0.5222
The network average Clustering coefficient0.168
The number (and %) of a zero Clustering coefficients9 (75.00 %)
The number (and %) of a zero Betweenness Centrality11 (91.67 %)

ACTIVE INTERACTORS
MISSING INTERACTORS (in fusions)


List of the fusions

PPI for parental proteins: DCTD All fusions
: AW946723;
Proteins found in more fusions DCTD (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 DCTDparental protein120.018108.000dCMP_cyt_deam_1 (PF00383, IPR002125): Cytidine and deoxycytidylate deaminase zinc-binding region
2 CEP76interactor100Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily
CEP76-C2 (PF15627, IPR028926): CEP76 C2 domain
3 ELAVL1oncoprotein31.0000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
4 FGF12oncoprotein100FGF (PF00167, IPR002209, SM00442): Fibroblast growth factor
5 GORASP2interactor100GRASP55_65 (PF04495, IPR024958): GRASP55/65 PDZ-like domain
6 LNX1interactor200PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
7 MALSU1interactor100RsfS (PF02410, IPR025656): Ribosomal silencing factor during starvation
8 NGRNinteractor100Neugrin (PF06413, IPR010487): Neugrin
9 NIF3L1interactor200NIF3 (PF01784, IPR002678): NIF3 (NGG1p interacting factor 3)
10 NUDT18interactor100NUDIX (PF00293, IPR000086): NUDIX domain
11 SDCBPinteractor21.0000PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
12 TXN2interactor100Thioredoxin (PF00085, IPR013766): Thioredoxin

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List of missing interactors (in fusions)

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 DCTDparental proteindCMP_cyt_deam_1 (PF00383, IPR002125): Cytidine and deoxycytidylate deaminase zinc-binding regionAW946723
2 ELAVL1oncoproteinRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)AW946723
3 NGRNinteractorNeugrin (PF06413, IPR010487): NeugrinAW946723
4 NUDT18interactorNUDIX (PF00293, IPR000086): NUDIX domainAW946723

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