1 |
CREBBP | parental protein | 296 | 0.058 | 51370.760 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) |
2 |
KAT6A | parental protein | 37 | 0.116 | 3199.892 | BUD22 (PF09073, IPR015158): BUD22 MOZ_SAS (PF01853, IPR002717): MOZ/SAS family PHD (PF00628, IPR019787, SM00249): PHD-finger Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306) zf-met (PF12874): Zinc-finger of C2H2 type |
3 |
ACTA2 | interactor | 5 | 0.800 | 0.677 | Actin (PF00022, IPR004000, SM00268): Actin |
4 |
AIRE | interactor | 17 | 0.383 | 28.550 | PHD (PF00628, IPR019787, SM00249): PHD-finger SAND (PF01342, IPR000770, SM00258): SAND domain HSR (PF03172, IPR004865): HSR domain; Sp100 domain zf-PHD-like (PF15446): PHD/FYVE-zinc-finger like domain |
5 |
AKT1 | oncoprotein | 39 | 0.277 | 258.926 | PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
6 |
ANAPC2 | interactor | 12 | 0.652 | 11.751 | ANAPC2 (PF08672, IPR014786, SM01013): Anaphase promoting complex (APC) subunit 2 Cullin (PF00888, IPR001373, SM00182): Cullin family |
7 |
ANAPC5 | interactor | 11 | 0.764 | 5.310 | TPR_4 (PF07721, IPR011717): Tetratricopeptide repeat ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5 TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
8 |
ANAPC7 | interactor | 11 | 0.844 | 2.575 | TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_21 (PF09976, IPR018704): Tetratricopeptide repeat-like domain ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat TPR_14 (PF13428): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
9 |
APC | suppressor | 10 | 0.333 | 26.488 | APC_15aa (PF05972, IPR009240): APC 15 residue motif APC_basic (PF05956, IPR009234): APC basic domain APC_r (PF05923): APC repeat Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) EB1_binding (PF05937, IPR009232): EB-1 Binding Domain FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) SAMP (PF05924, IPR009224): SAMP Motif Suppressor_APC (PF11414, IPR026831): Adenomatous polyposis coli tumour suppressor protein AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term SAS4 (PF15460, IPR029184): Something about silencing, SAS, complex subunit 4 Arm_APC_u3 (PF16629): Armadillo-associated region on APC APC_u5 (PF16630): Unstructured region on APC between 1st and 2nd catenin-bdg motifs APC_u9 (PF16633): Unstructured region on APC between 1st two creatine-rich regions APC_u13 (PF16634): Unstructured region on APC between APC_crr and SAMP APC_u14 (PF16635): Unstructured region on APC between SAMP and APC_crr APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6 APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain |
10 |
AR | oncoprotein | 52 | 0.300 | 303.019 | Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
11 |
ARNTL | suppressor | 10 | 0.578 | 9.738 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_11 (PF14598): PAS domain |
12 |
ATF1 | oncoprotein | 7 | 0.619 | 2.790 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor pKID (PF02173, IPR003102): pKID domain DUF4988 (PF16378, IPR032149): Domain of unknown function |
13 |
ATF2 | oncoprotein | 28 | 0.345 | 83.285 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type |
14 |
ATF3 | suppressor | 26 | 0.400 | 95.823 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
15 |
ATF4 | oncoprotein | 17 | 0.492 | 29.093 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
16 |
ATG3 | interactor | 1 | 0 | 0 | Autophagy_C (PF10381, IPR019461): Autophagocytosis associated protein C-terminal Autophagy_N (PF03986, IPR007134): Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C (PF03987, IPR007135): Autophagocytosis associated protein, active-site domain |
17 |
ATN1 | protein found in more fusions | 7 | 0.200 | 19.019 | Atrophin-1 (PF03154, IPR002951): Atrophin-1 family |
18 |
ATXN1 | protein found in more fusions | 16 | 0.171 | 80.536 | AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH) Spt20 (PF12090, IPR021950): Spt20 family ATXN-1_C (PF12547, IPR020997): Capicua transcriptional repressor modulator Cnd1_N (PF12922, IPR024324): non-SMC mitotic condensation complex subunit 1, N-term |
19 |
ATXN3 | interactor | 18 | 0.272 | 107.487 | Josephin (PF02099, IPR006155): Josephin UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
20 |
BCL6 | oncoprotein | 23 | 0.325 | 97.965 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding DZR (PF12773, IPR025874): Double zinc ribbon zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger |
21 |
BMI1 | oncoprotein | 23 | 0.307 | 229.674 | zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
22 |
BRCA1 | suppressor | 59 | 0.282 | 469.774 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT |
23 |
BRMS1 | suppressor | 14 | 0.551 | 12.593 | Dynactin_p62 (PF05502, IPR008603): Dynactin p62 family Sds3 (PF08598, IPR013907): Sds3-like |
24 |
BRPF1 | interactor | 6 | 0.333 | 10.313 | Pap_E4 (PF02711, IPR003861): E4 protein PGA2 (PF07543, IPR011431): Protein trafficking PGA2 PWWP (PF00855, IPR000313, SM00293): PWWP domain EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Bromodomain (PF00439, IPR001487, SM00297): Bromodomain DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570) PHD_2 (PF13831): PHD-finger zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain |
25 |
C3orf62 | interactor | 3 | 0.667 | 12.241 | DUF4712 (PF15830, IPR031670): Domain of unknown function (DUF4712) |
26 |
CARM1 | oncoprotein | 26 | 0.360 | 198.474 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase CBP_GIL (PF10995, IPR017745): GGDEF I-site like or GIL domain CARM1 (PF11531, IPR020989): Coactivator-associated arginine methyltransferase 1 N terminal |
27 |
CCNA2 | oncoprotein | 21 | 0.447 | 51.216 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain Cyclin_N2 (PF16500, IPR032447): N-terminal region of cyclin_N |
28 |
CCNB1 | oncoprotein | 17 | 0.324 | 69.128 | Adeno_E1A (PF02703, IPR003853): Early E1A protein Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain |
29 |
CCNC | suppressor | 6 | 1.000 | 0 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain Cyclin_C_2 (PF16899, IPR031658): Cyclin C-terminal domain |
30 |
CCND3 | oncoprotein | 8 | 0.464 | 4.422 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain |
31 |
CCNE1 | oncoprotein | 16 | 0.383 | 28.042 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain |
32 |
CDC16 | interactor | 14 | 0.560 | 23.923 | Dynein_light (PF01221, IPR001372): Dynein light chain type 1 TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat SRP_TPR_like (PF17004, IPR031545): Putative TPR-like repeat |
33 |
CDC20 | oncoprotein | 24 | 0.383 | 101.362 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
34 |
CDC27 | oncoprotein | 22 | 0.352 | 69.296 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat |
35 |
CDH1 | suppressor | 12 | 0.491 | 12.587 | Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like Cadherin (PF00028, IPR002126, SM00112): Cadherin domain |
36 |
CDH2 | interactor | 3 | 1.000 | 0 | Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like Cadherin (PF00028, IPR002126, SM00112): Cadherin domain EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain Cadherin_3 (PF16184): Cadherin-like |
37 |
CDK2 | suppressor | 52 | 0.234 | 523.725 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
38 |
CDK8 | interactor | 27 | 0.372 | 349.393 | Pkinase (PF00069, IPR000719): Protein kinase domain |
39 |
CDKN1A | suppressor | 40 | 0.277 | 308.066 | CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor |
40 |
CEBPB | oncoprotein | 43 | 0.347 | 172.301 | RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
41 |
CEBPD | suppressor | 12 | 0.561 | 7.981 | bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 |
42 |
CENPJ | interactor | 4 | 0.167 | 95.020 | DASH_Hsk3 (PF08227, IPR013183): DASH complex subunit Hsk3 like DUF1795 (PF08786, IPR014894): Domain of unknown function (DUF1795) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Rota_VP2 (PF05087, IPR007779): Rotavirus VP2 protein Tcp10_C (PF07202, IPR009852): T-complex protein 10 C-terminus TSC22 (PF01166, IPR000580): TSC-22/dip/bun family AAA_23 (PF13476): AAA domain DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140) |
43 |
CHUK | suppressor | 25 | 0.446 | 59.730 | Pkinase (PF00069, IPR000719): Protein kinase domain IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain |
44 |
CITED1 | interactor | 6 | 0.667 | 3.138 | CITED (PF04487, IPR007576): CITED |
45 |
CITED2 | suppressor | 8 | 0.536 | 5.453 | CITED (PF04487, IPR007576): CITED |
46 |
CLOCK | interactor | 6 | 1.000 | 0 | DivIC (PF04977, IPR007060): Septum formation initiator HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) PAS (PF00989, IPR013767, SM00091): PAS fold RNA_pol_Rpb4 (PF03874, IPR005574): RNA polymerase Rpb4 PAS_11 (PF14598): PAS domain FlgT_N (PF16548, IPR032370): Flagellar assembly protein T, N-terminal domain |
47 |
COPS2 | suppressor | 15 | 0.419 | 23.316 | YozE_SAM_like (PF06855, IPR023089): YozE SAM-like fold TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat DUF2087 (PF09860, IPR018656): Uncharacterized protein conserved in bacteria (DUF2087) PCI (PF01399, IPR000717, SM00088): PCI domain TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat |
48 |
CPSF6 | interactor | 9 | 0.361 | 33.577 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
49 |
CREB1 | oncoprotein | 38 | 0.266 | 260.946 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor pKID (PF02173, IPR003102): pKID domain DUF4988 (PF16378, IPR032149): Domain of unknown function |
50 |
CREM | suppressor | 8 | 0.464 | 17.663 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor pKID (PF02173, IPR003102): pKID domain DUF3987 (PF13148, IPR025048): Protein of unknown function (DUF3987) |
51 |
CRK | oncoprotein | 12 | 0.167 | 68.670 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
52 |
CRTC1 | oncoprotein | 4 | 0.833 | 1.175 | TORC_N (PF12884, IPR024783): Transducer of regulated CREB activity, N terminus TORC_M (PF12885, IPR024784): Transducer of regulated CREB activity middle domain TORC_C (PF12886, IPR024785): Transducer of regulated CREB activity, C terminus |
53 |
CSNK2A1 | oncoprotein | 43 | 0.200 | 518.758 | Pkinase (PF00069, IPR000719): Protein kinase domain |
54 |
CSNK2A2 | interactor | 12 | 0.273 | 49.608 | Pkinase (PF00069, IPR000719): Protein kinase domain |
55 |
CTBP1 | protein found in more fusions | 32 | 0.310 | 177.725 | 2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D |
56 |
CTNNB1 | oncoprotein | 51 | 0.221 | 505.537 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat |
57 |
CUX1 | suppressor | 3 | 0.667 | 0.167 | Baculo_p24 (PF05073, IPR007765): Baculovirus P24 capsid protein CUT (PF02376, IPR003350, SM01109): CUT domain DegS (PF05384, IPR008595): Sensor protein DegS DivIC (PF04977, IPR007060): Septum formation initiator DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein Swi5 (PF07061, IPR010760): Swi5 TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein ApoO (PF09769, IPR019166): Apolipoprotein O Homeobox (PF00046, IPR001356, SM00389): Homeobox domain RIC3 (PF15361, IPR032763): Resistance to inhibitors of cholinesterase homologue 3 PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082) |
58 |
DAXX | oncoprotein | 34 | 0.277 | 255.377 | Daxx (PF03344, IPR005012): Daxx N-terminal Rassf1C-interacting domain Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Nop14 (PF04147, IPR007276): Nop14-like family RF-1 (PF00472, IPR000352): RF-1 domain Vpu (PF00558, IPR008187): Vpu protein DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391) |
59 |
DDIT3 | oncoprotein | 16 | 0.524 | 19.655 | IFP_35_N (PF07334, IPR009938): Interferon-induced 35 kDa protein (IFP 35) N-terminus bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper |
60 |
DDX17 | protein found in more fusions | 22 | 0.400 | 97.292 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Ferritin (PF00210, IPR008331): Ferritin-like domain GRP (PF07172, IPR010800): Glycine rich protein family Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
61 |
DDX5 | oncoprotein | 29 | 0.354 | 170.485 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
62 |
DEK | oncoprotein | 15 | 0.438 | 43.415 | DEK_C (PF08766, IPR014876): DEK C terminal domain Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family SAP (PF02037, IPR003034, SM00513): SAP domain Bud13 (PF09736, IPR018609): Pre-mRNA-splicing factor of RES complex DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) TFIIE-A_C (PF11521, IPR021600): C-terminal general transcription factor TFIIE alpha PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal |
63 |
DYRK1A | oncoprotein | 14 | 0.397 | 19.382 | DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region Pkinase (PF00069, IPR000719): Protein kinase domain FAM199X (PF15814, IPR029672): Protein family FAM199X |
64 |
DYRK1B | oncoprotein | 8 | 0.524 | 4.308 | Pkinase (PF00069, IPR000719): Protein kinase domain |
65 |
E2F1 | suppressor | 34 | 0.319 | 164.533 | Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain |
66 |
E2F3 | suppressor | 11 | 0.273 | 24.829 | E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain |
67 |
EBF1 | oncoprotein | 3 | 1.000 | 0 | TIG (PF01833, IPR002909): IPT/TIG domain COE1_DBD (PF16422, IPR032200): Transcription factor COE1 DNA-binding domain COE1_HLH (PF16423, IPR032201): Transcription factor COE1 helix-loop-helix domain |
68 |
EGR1 | suppressor | 11 | 0.564 | 6.629 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type DUF3432 (PF11914, IPR021839): Domain of unknown function (DUF3432) DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
69 |
EID1 | interactor | 8 | 0.643 | 3.870 | NA |
70 |
EID3 | interactor | 3 | 1.000 | 0 | Nse4_C (PF08743, IPR014854): Nse4 C-terminal Nse4-Nse3_bdg (PF15412, IPR029225): Binding domain of Nse4/EID3 to Nse3-MAGE |
71 |
ELAVL1 | oncoprotein | 63 | 0.116 | 1425.709 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
72 |
ELK1 | oncoprotein | 13 | 0.318 | 47.487 | Ets (PF00178, IPR000418, SM00413): Ets-domain Ribosomal_L12_N (PF16320, IPR008932): Ribosomal protein L7/L12 dimerisation domain |
73 |
EP300 | oncoprotein | 180 | 0.095 | 10807.416 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type |
74 |
EPAS1 | suppressor | 20 | 0.363 | 49.405 | Corona_I (PF03187, IPR004876): Corona nucleocapsid I protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 PAS_11 (PF14598): PAS domain |
75 |
ESR1 | suppressor | 84 | 0.211 | 1437.868 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
76 |
ESR2 | suppressor | 24 | 0.360 | 54.488 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ERbeta_N (PF12497, IPR021064): Estrogen receptor beta |
77 |
ETS1 | oncoprotein | 24 | 0.446 | 57.517 | Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain |
78 |
ETS2 | suppressor | 11 | 0.800 | 2.018 | Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain |
79 |
EWSR1 | oncoprotein | 43 | 0.185 | 629.970 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
80 |
FGFR1 | oncoprotein | 9 | 0.357 | 27.621 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
81 |
FHL1 | suppressor | 11 | 0.709 | 3.884 | LIM (PF00412, IPR001781, SM00132): LIM domain zf-FCS (PF06467, IPR010507): MYM-type Zinc finger with FCS sequence motif |
82 |
FHL2 | oncoprotein | 27 | 0.351 | 100.412 | LIM (PF00412, IPR001781, SM00132): LIM domain zf-ribbon_3 (PF13248): zinc-ribbon domain |
83 |
FOS | oncoprotein | 36 | 0.304 | 180.402 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
84 |
FOSB | oncoprotein | 4 | 1.000 | 0 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Motilin_ghrelin (PF04644, IPR006738): Motilin/ghrelin |
85 |
FOSL1 | oncoprotein | 12 | 0.561 | 31.011 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
86 |
FOXM1 | oncoprotein | 10 | 0.422 | 14.991 | EspF (PF04806, IPR006891): EspF protein repeat Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
87 |
FOXO1 | suppressor | 24 | 0.375 | 80.623 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain Forkhead (PF00250, IPR001766, SM00339): Forkhead domain FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2 FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family |
88 |
FOXO3 | suppressor | 19 | 0.497 | 26.294 | Lin-8 (PF03353, IPR005020): Ras-mediated vulval-induction antagonist Forkhead (PF00250, IPR001766, SM00339): Forkhead domain FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2 FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family |
89 |
FOXO4 | suppressor | 12 | 0.500 | 10.611 | Forkhead (PF00250, IPR001766, SM00339): Forkhead domain FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2 FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family |
90 |
GATA1 | oncoprotein | 11 | 0.527 | 40.534 | GATA (PF00320, IPR000679, SM00401): GATA zinc finger Vps36-NZF-N (PF16988, IPR031558): Vacuolar protein sorting 36 NZF-N zinc-finger domain |
91 |
GCM1 | interactor | 4 | 0.667 | 0.159 | DUF1272 (PF06906, IPR010696): Protein of unknown function (DUF1272) GCM (PF03615, IPR003902): GCM motif protein |
92 |
GLI3 | oncoprotein | 3 | 1.000 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain |
93 |
GRIP1 | protein found in more fusions | 15 | 0.626 | 6.004 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) |
94 |
GTF2B | interactor | 18 | 0.392 | 66.112 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain TFIIB (PF00382, IPR013150): Transcription factor TFIIB repeat TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding |
95 |
H3F3C | oncoprotein | 3 | 0.333 | 2.808 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
96 |
HBP1 | suppressor | 7 | 0.762 | 1.439 | AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH) HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box |
97 |
HCK | oncoprotein | 8 | 0.500 | 19.247 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
98 |
HDAC1 | suppressor | 100 | 0.170 | 2457.287 | FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
99 |
HDAC2 | suppressor | 64 | 0.217 | 696.451 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1 |
100 |
HDAC3 | suppressor | 53 | 0.241 | 381.505 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
101 |
HEMGN | interactor | 5 | 0.300 | 7.280 | BRF1 (PF07741, IPR011665): Brf1-like TBP-binding domain |
102 |
HES6 | interactor | 1 | 0 | 0 | Hairy_orange (PF07527, IPR003650): Hairy Orange HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
103 |
HIF1A | suppressor | 35 | 0.450 | 97.735 | Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 |
104 |
HIPK2 | suppressor | 23 | 0.307 | 108.617 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
105 |
HIST1H2BB | interactor | 11 | 0.509 | 10.975 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
106 |
HIST1H3A | interactor | 37 | 0.243 | 497.990 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
107 |
HIST1H4A | interactor | 28 | 0.317 | 120.826 | CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold |
108 |
HIST1H4I | oncoprotein | 1 | 0 | 0 | CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold |
109 |
HIST2H2BE | interactor | 16 | 0.442 | 21.436 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
110 |
HIST2H3C | interactor | 17 | 0.206 | 106.217 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
111 |
HIST3H3 | interactor | 28 | 0.288 | 165.108 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
112 |
HIST4H4 | interactor | 13 | 0.474 | 17.542 | CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold |
113 |
HMGA1 | oncoprotein | 23 | 0.364 | 104.215 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF2239 (PF09998, IPR018715): Uncharacterized protein conserved in bacteria (DUF2239) |
114 |
HMGB1 | oncoprotein | 18 | 0.307 | 58.793 | HMG_box_2 (PF09011, IPR009071): HMG-box domain NOA36 (PF06524, IPR010531): NOA36 protein HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box |
115 |
HMGB2 | protein found in more fusions | 7 | 0.571 | 2.003 | HMG_box_2 (PF09011, IPR009071): HMG-box domain NOA36 (PF06524, IPR010531): NOA36 protein HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box |
116 |
HNF1A | oncoprotein | 10 | 0.556 | 4.171 | HNF-1_N (PF04814, IPR006899): Hepatocyte nuclear factor 1 (HNF-1), N terminus HNF-1A_C (PF04813, IPR006898): Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus HNF-1B_C (PF04812, IPR006897): Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
117 |
HNF4A | suppressor | 27 | 0.363 | 64.000 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
118 |
HOXA10 | interactor | 3 | 0.667 | 0.400 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DUF4266 (PF14086, IPR025362): Domain of unknown function (DUF4266) |
119 |
HOXA9 | oncoprotein | 5 | 0.500 | 2.854 | Hox9_act (PF04617, IPR006711): Hox9 activation region Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
120 |
HOXB2 | interactor | 1 | 0 | 0 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
121 |
HOXB3 | interactor | 2 | 1.000 | 0 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DUF4074 (PF13293, IPR025281): Domain of unknown function (DUF4074) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
122 |
HOXB4 | interactor | 1 | 0 | 0 | DUF4106 (PF13388, IPR025179): Protein of unknown function (DUF4106) |
123 |
HOXB6 | interactor | 1 | 0 | 0 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
124 |
HOXB7 | interactor | 4 | 0.667 | 0.950 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
125 |
HOXB9 | interactor | 2 | 1.000 | 0 | Hox9_act (PF04617, IPR006711): Hox9 activation region Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
126 |
HOXD10 | interactor | 3 | 0.667 | 0.198 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
127 |
HOXD12 | interactor | 3 | 0.667 | 0.500 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
128 |
HOXD13 | oncoprotein | 5 | 0.600 | 1.011 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain HoxA13_N (PF12284, IPR022067): Hox protein A13 N terminal |
129 |
HOXD4 | interactor | 6 | 0.400 | 34.910 | SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DGF-1_C (PF11040, IPR021053): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus |
130 |
HSF1 | protein found in more fusions | 18 | 0.316 | 91.793 | DUF247 (PF03140, IPR004158): Plant protein of unknown function Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding |
131 |
HSPA4 | interactor | 28 | 0.270 | 145.111 | Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5 |
132 |
HTT | protein found in more fusions | 19 | 0.366 | 54.706 | HEAT (PF02985, IPR000357): HEAT repeat SPX (PF03105, IPR004331): SPX domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF3652 (PF12372, IPR024613): Huntingtin protein region Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
133 |
IFNAR2 | interactor | 5 | 1.000 | 0 | Interfer-bind (PF09294, IPR015373): Interferon-alpha/beta receptor, fibronectin type III Tissue_fac (PF01108, IPR003961): Tissue factor |
134 |
IKBKB | protein found in more fusions | 15 | 0.495 | 10.455 | FliT (PF05400, IPR008622): Flagellar protein FliT Glyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain Pkinase (PF00069, IPR000719): Protein kinase domain SlyX (PF04102, IPR007236): SlyX ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain |
135 |
IKBKG | interactor | 18 | 0.301 | 41.739 | CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725) NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator |
136 |
ING1 | suppressor | 18 | 0.477 | 32.263 | PHD (PF00628, IPR019787, SM00249): PHD-finger NPR3 (PF03666, IPR005365): Nitrogen Permease regulator of amino acid transport activity 3 ING (PF12998, IPR024610): Inhibitor of growth proteins N-terminal histone-binding zf-C4pol (PF14260, IPR025687): C4-type zinc-finger of DNA polymerase delta |
137 |
ING5 | suppressor | 9 | 0.278 | 87.594 | ING (PF12998, IPR024610): Inhibitor of growth proteins N-terminal histone-binding |
138 |
IRF1 | suppressor | 10 | 0.533 | 10.264 | IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor |
139 |
IRF3 | suppressor | 13 | 0.470 | 21.276 | IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3 |
140 |
IRF5 | suppressor | 10 | 0.556 | 4.618 | IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3 |
141 |
IRF7 | interactor | 9 | 0.714 | 3.399 | IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3 |
142 |
IRF9 | interactor | 7 | 0.571 | 6.130 | IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3 |
143 |
JUN | oncoprotein | 70 | 0.239 | 862.804 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor |
144 |
JUNB | oncoprotein | 16 | 0.400 | 27.415 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor |
145 |
KAT2B | protein found in more fusions | 76 | 0.151 | 1354.192 | Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain |
146 |
KAT5 | suppressor | 39 | 0.290 | 360.999 | MOZ_SAS (PF01853, IPR002717): MOZ/SAS family Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain |
147 |
KDM3B | suppressor | 4 | 0.500 | 1.312 | JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase zf-C5HC2 (PF02928, IPR004198): C5HC2 zinc finger |
148 |
KHDRBS1 | protein found in more fusions | 17 | 0.317 | 68.154 | KH_1 (PF00013, IPR004088, SM00322): KH domain Qua1 (PF16274, IPR032571): Qua1 domain Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68 |
149 |
KLF1 | interactor | 7 | 0.571 | 3.026 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain EKLF_TAD1 (PF16832, IPR031786): Erythroid krueppel-like transcription factor, transactivation 1 EKLF_TAD2 (PF16833, IPR031784): Erythroid krueppel-like transcription factor, transactivation 2 |
150 |
KLF13 | interactor | 5 | 0.800 | 0.650 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
151 |
KLF2 | interactor | 5 | 0.500 | 1.487 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
152 |
KLF4 | suppressor | 12 | 0.621 | 6.603 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
153 |
KLF5 | suppressor | 23 | 0.518 | 24.711 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
154 |
KLF8 | interactor | 5 | 0.900 | 0.133 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
155 |
KMT2A | oncoprotein | 26 | 0.320 | 173.492 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 SET (PF00856, IPR001214, SM00317): SET domain zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain zf-HC5HC2H (PF13771): PHD-like zinc-binding domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) |
156 |
KPNA2 | interactor | 13 | 0.449 | 15.192 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat IBB (PF01749, IPR002652): Importin beta binding domain Arm_3 (PF16186, IPR032413): Atypical Arm repeat |
157 |
KPNA6 | interactor | 8 | 0.250 | 15.251 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat IBB (PF01749, IPR002652): Importin beta binding domain Arm_3 (PF16186, IPR032413): Atypical Arm repeat |
158 |
L1TD1 | interactor | 2 | 0 | 1.304 | FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) Occludin_ELL (PF07303, IPR010844): Occludin homology domain PDEase_I (PF00233, IPR002073): 3'5'-cyclic nucleotide phosphodiesterase Transposase_22 (PF02994, IPR004244): L1 transposable element |
159 |
LDLR | interactor | 1 | 0 | 0 | EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A Ldl_recept_b (PF00058, IPR000033, SM00135): Low-density lipoprotein receptor repeat class B hEGF (PF12661, IPR013032): Human growth factor-like EGF FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site |
160 |
LIG4 | interactor | 2 | 1.000 | 0 | APG17 (PF04108, IPR007240): Autophagy protein Apg17 BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain DNA_ligase_A_C (PF04679, IPR012309): ATP dependent DNA ligase C terminal region DNA_ligase_A_M (PF01068, IPR012310): ATP dependent DNA ligase domain DNA_ligase_A_N (PF04675, IPR012308): DNA ligase N terminus DNA_ligase_IV (PF11411, IPR021536): DNA ligase IV RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
161 |
LYN | oncoprotein | 14 | 0.372 | 45.099 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
162 |
MAF | oncoprotein | 13 | 0.424 | 20.704 | bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor Maf_N (PF08383, IPR013592): Maf N-terminal region NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region Sporozoite_P67 (PF05642, IPR008845): Sporozoite P67 surface antigen TraT (PF05818, IPR008874): Enterobacterial TraT complement resistance protein Metal_resist (PF13801, IPR025961): Heavy-metal resistance |
163 |
MAFK | oncoprotein | 12 | 0.561 | 29.086 | bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor |
164 |
MAML1 | interactor | 6 | 0.533 | 4.528 | MamL-1 (PF09596, IPR019082): MamL-1 domain Kri1 (PF05178, IPR018034): KRI1-like family PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
165 |
MAML2 | oncoprotein | 3 | 1.000 | 0 | Senescence_reg (PF04520, IPR007608): Senescence regulator BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal MamL-1 (PF09596, IPR019082): MamL-1 domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like WBP-1 (PF11669, IPR021684): WW domain-binding protein 1 SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
166 |
MAP3K5 | oncoprotein | 10 | 0.389 | 10.994 | Pkinase (PF00069, IPR000719): Protein kinase domain DUF4071 (PF13281, IPR025136): Domain of unknown function (DUF4071) |
167 |
MAPK1 | oncoprotein | 41 | 0.281 | 258.927 | Pkinase (PF00069, IPR000719): Protein kinase domain |
168 |
MAPK10 | suppressor | 9 | 0.571 | 2.634 | Pkinase (PF00069, IPR000719): Protein kinase domain |
169 |
MAPK3 | oncoprotein | 24 | 0.285 | 163.120 | Pkinase (PF00069, IPR000719): Protein kinase domain |
170 |
MDC1 | suppressor | 18 | 0.399 | 55.748 | FHA (PF00498, IPR000253, SM00240): FHA domain DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274) Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
171 |
MDM2 | oncoprotein | 63 | 0.203 | 887.781 | Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
172 |
MEAF6 | interactor | 6 | 0.333 | 16.795 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) NuA4 (PF09340, IPR015418): Histone acetyltransferase subunit NuA4 |
173 |
MECOM | oncoprotein | 11 | 0.582 | 5.180 | SET (PF00856, IPR001214, SM00317): SET domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger |
174 |
MED21 | protein found in more fusions | 20 | 0.404 | 42.376 | Med21 (PF11221, IPR021384): Subunit 21 of Mediator complex |
175 |
MED23 | interactor | 33 | 0.256 | 326.286 | Med23 (PF11573, IPR021629): Mediator complex subunit 23 |
176 |
MED25 | interactor | 10 | 0.472 | 6.434 | Med25 (PF11232, IPR021394): Mediator complex subunit 25 PTOV activation and synapsin 2 Med25_SD1 (PF11235, IPR021397): Mediator complex subunit 25 synapsin 1 Med25_NR-box (PF11244, IPR021406): Mediator complex subunit 25 C-terminal NR box-containing Med25_VWA (PF11265, IPR021419): Mediator complex subunit 25 von Willebrand factor type A |
177 |
MEIS1 | oncoprotein | 6 | 0.467 | 5.200 | Homeobox_KN (PF05920, IPR008422): Homeobox KN domain Meis_PKNOX_N (PF16493, IPR032453): N-terminal of Homeobox Meis and PKNOX1 |
178 |
MGMT | interactor | 14 | 0.462 | 23.215 | DNA_binding_1 (PF01035, IPR014048): 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N (PF02870, IPR008332): 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain |
179 |
MIER1 | oncoprotein | 5 | 0.800 | 0.248 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain ELM2 (PF01448, IPR000949): ELM2 domain HpaP (PF09483, IPR013390): Type III secretion protein (HpaP) SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain SpoIIIAH (PF12685, IPR024232): SpoIIIAH-like protein |
180 |
MKNK1 | interactor | 6 | 0.400 | 4.432 | Pkinase (PF00069, IPR000719): Protein kinase domain |
181 |
MSH2 | suppressor | 17 | 0.483 | 22.162 | MutS_I (PF01624, IPR007695): MutS domain I MutS_II (PF05188, IPR007860): MutS domain II MutS_V (PF00488, IPR000432, SM00534): MutS domain V MutS_III (PF05192, IPR007696, SM00533): MutS domain III AAA_27 (PF13514): AAA domain |
182 |
MSH6 | oncoprotein | 10 | 0.756 | 2.801 | MutS_I (PF01624, IPR007695): MutS domain I MutS_II (PF05188, IPR007860): MutS domain II PWWP (PF00855, IPR000313, SM00293): PWWP domain MutS_V (PF00488, IPR000432, SM00534): MutS domain V MutS_III (PF05192, IPR007696, SM00533): MutS domain III UPF0524 (PF15823, IPR029670): UPF0524 of C3orf70 |
183 |
MSX1 | protein found in more fusions | 4 | 1.000 | 0 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
184 |
MTDH | interactor | 4 | 0.833 | 0.083 | NST1 (PF13945, IPR025279): Salt tolerance down-regulator NAM-associated (PF14303, IPR029466): No apical meristem-associated C-terminal domain LYRIC (PF15686, IPR031402): Lysine-rich CEACAM1 co-isolated protein family |
185 |
MTF1 | interactor | 2 | 1.000 | 0 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Marek_A (PF02124, IPR001038): Marek's disease glycoprotein A zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
186 |
MUS81 | suppressor | 4 | 0.333 | 17.019 | ERCC4 (PF02732, IPR006166, SM00891): ERCC4 domain MutL (PF13941, IPR006230): MutL protein HHH_8 (PF14716, IPR010996): Helix-hairpin-helix domain |
187 |
MYB | oncoprotein | 18 | 0.346 | 44.317 | Cmyb_C (PF09316, IPR015395): C-myb, C-terminal LMSTEN (PF07988, IPR012642): LMSTEN motif Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
188 |
MYBL1 | oncoprotein | 3 | 1.000 | 0 | Cmyb_C (PF09316, IPR015395): C-myb, C-terminal LMSTEN (PF07988, IPR012642): LMSTEN motif Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
189 |
MYBL2 | oncoprotein | 13 | 0.394 | 20.293 | Cmyb_C (PF09316, IPR015395): C-myb, C-terminal Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
190 |
MYC | oncoprotein | 58 | 0.286 | 666.249 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
191 |
MYH9 | suppressor | 13 | 0.410 | 24.671 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
192 |
MYOD1 | oncoprotein | 22 | 0.452 | 32.545 | Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Mfp-3 (PF04202, IPR007328): Foot protein 3 Myf5 (PF12232, IPR022032): Myogenic determination factor 5 |
193 |
N4BP2 | interactor | 4 | 1.000 | 0 | CUE (PF02845, IPR003892, SM00546): CUE domain DUF1771 (PF08590, IPR013899, SM01162): Domain of unknown function (DUF1771) RyR (PF02026, IPR003032): RyR domain Smr (PF01713, IPR002625, SM00463): Smr domain AAA_22 (PF13401, IPR003593): AAA domain AAA_33 (PF13671): AAA domain |
194 |
NCOA1 | oncoprotein | 38 | 0.366 | 137.596 | DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein |
195 |
NCOA2 | oncoprotein | 26 | 0.369 | 76.951 | DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein |
196 |
NCOA3 | oncoprotein | 40 | 0.312 | 212.838 | DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3 |
197 |
NCOA6 | oncoprotein | 34 | 0.352 | 123.312 | DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719) Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1 Presenilin (PF01080, IPR001108): Presenilin DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) Nucleic_acid_bd (PF13820, IPR032715): Putative nucleic acid-binding region NST1 (PF13945, IPR025279): Salt tolerance down-regulator |
198 |
NCOR1 | oncoprotein | 50 | 0.286 | 357.688 | BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp) MAS20 (PF02064, IPR002056): MAS20 protein import receptor Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein Hid1 (PF12722): High-temperature-induced dauer-formation protein Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) RBR (PF17208): RNA binding Region |
199 |
NCOR2 | oncoprotein | 38 | 0.397 | 139.515 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal MAS20 (PF02064, IPR002056): MAS20 protein import receptor OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK) SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Gti1_Pac2 (PF09729, IPR018608): Gti1/Pac2 family PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Spt20 (PF12090, IPR021950): Spt20 family DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4518 (PF15008, IPR026698): Domain of unknown function (DUF4518) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820) |
200 |
NEUROG1 | interactor | 3 | 1.000 | 0 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Transformer (PF06495, IPR010519): Fruit fly transformer protein |
201 |
NFATC2 | suppressor | 5 | 1.000 | 0 | RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
202 |
NFATC4 | interactor | 2 | 1.000 | 0 | RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
203 |
NFE2 | interactor | 5 | 0.833 | 0.222 | bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor Peptidase_Mx (PF15887, IPR031321): Putative zinc-binding metallo-peptidase |
204 |
NFE2L2 | oncoprotein | 18 | 0.444 | 36.254 | bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor |
205 |
NFYB | interactor | 13 | 0.654 | 8.924 | CBFD_NFYB_HMF (PF00808, IPR003958): Histone-like transcription factor (CBF/NF-Y) and archaeal histone |
206 |
NKX2-1 | oncoprotein | 7 | 0.619 | 2.102 | DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DUF4719 (PF15843, IPR031696): Domain of unknown function (DUF4719) |
207 |
NLK | protein found in more fusions | 16 | 0.314 | 65.664 | Pkinase (PF00069, IPR000719): Protein kinase domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit |
208 |
NPAS2 | suppressor | 7 | 0.905 | 0.800 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold DehI (PF10778, IPR019714): Halocarboxylic acid dehydrogenase DehI PAS_11 (PF14598): PAS domain |
209 |
NPAT | interactor | 5 | 0.500 | 2.832 | Rxt3 (PF08642, IPR013951): Histone deacetylation protein Rxt3 TERB2 (PF15101, IPR028065): Telomere-associated protein TERB2 NPAT_C (PF15712, IPR031442): NPAT C terminus |
210 |
NR3C1 | protein found in more fusions | 44 | 0.302 | 297.870 | GCR (PF02155, IPR001409): Glucocorticoid receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
211 |
NR3C2 | oncoprotein | 7 | 0.619 | 1.699 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
212 |
NR5A1 | interactor | 9 | 0.444 | 6.202 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
213 |
NUP98 | suppressor | 8 | 0.536 | 6.800 | Nucleoporin2 (PF04096, IPR007230): Nucleoporin autopeptidase Nup96 (PF12110, IPR021967): Nuclear protein 96 ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region Keratin_2_head (PF16208, IPR032444): Keratin type II head |
214 |
ONECUT1 | suppressor | 3 | 0.667 | 0.154 | CUT (PF02376, IPR003350, SM01109): CUT domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
215 |
PAPOLA | interactor | 7 | 0.381 | 5.833 | PAP_central (PF04928, IPR007012): Poly(A) polymerase central domain PAP_RNA-bind (PF04926, IPR007010): Poly(A) polymerase predicted RNA binding domain Macoilin (PF09726, IPR019130): Transmembrane protein |
216 |
PARP1 | suppressor | 47 | 0.281 | 390.917 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain WGR (PF05406, IPR008893, SM00773): WGR domain zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region |
217 |
PBX1 | oncoprotein | 13 | 0.295 | 44.347 | PBC (PF03792, IPR005542): PBC domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
218 |
PCNA | oncoprotein | 35 | 0.278 | 238.259 | PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain |
219 |
PELP1 | interactor | 15 | 0.400 | 46.581 | RIX1 (PF08167, IPR012583): rRNA processing/ribosome biogenesis NUC202 (PF08166, IPR012980): NUC202 domain RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5 DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) |
220 |
PHF14 | interactor | 3 | 0.333 | 1.838 | Atrophin-1 (PF03154, IPR002951): Atrophin-1 family BSP_II (PF05432, IPR008412): Bone sialoprotein II (BSP-II) C1_2 (PF03107, IPR004146): C1 domain Ctr (PF04145, IPR007274): Ctr copper transporter family DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342) LicD (PF04991, IPR007074): LicD family PHD (PF00628, IPR019787, SM00249): PHD-finger Rrp15p (PF07890, IPR012459): Rrp15p C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain zf-PHD-like (PF15446): PHD/FYVE-zinc-finger like domain |
221 |
PHOX2A | suppressor | 4 | 1.000 | 0 | Phage_Mu_Gam (PF07352, IPR009951): Bacteriophage Mu Gam like protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
222 |
PHOX2B | oncoprotein | 1 | 0 | 0 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein TraC (PF07820, IPR012930): TraC-like protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
223 |
PIAS3 | oncoprotein | 13 | 0.500 | 13.348 | SAP (PF02037, IPR003034, SM00513): SAP domain zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain |
224 |
PLAGL1 | suppressor | 10 | 0.778 | 1.277 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger |
225 |
PML | suppressor | 54 | 0.250 | 674.942 | zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
226 |
PNPLA8 | interactor | 1 | 0 | 0 | ATP-synt_E (PF05680, IPR008386): ATP synthase E chain DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) SMC_ScpB (PF04079, IPR005234): Segregation and condensation complex subunit ScpB Patatin (PF01734, IPR002641): Patatin-like phospholipase |
227 |
POLR2A | protein found in more fusions | 34 | 0.294 | 145.053 | RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat |
228 |
POT1 | interactor | 8 | 0.381 | 23.701 | POT1 (PF02765, IPR011564, SM00976): Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain POT1PC (PF16686, IPR032042): ssDNA-binding domain of telomere protection protein |
229 |
POU1F1 | interactor | 7 | 0.714 | 1.390 | Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain Lsr2 (PF11774, IPR024412): Lsr2 |
230 |
POU2F3 | suppressor | 2 | 1.000 | 0 | Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
231 |
PPARG | suppressor | 37 | 0.395 | 105.584 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor PPARgamma_N (PF12577, IPR022590): PPAR gamma N-terminal region |
232 |
PPARGC1A | interactor | 17 | 0.522 | 15.851 | Pap_E4 (PF02711, IPR003861): E4 protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSRP (PF17069): Arginine/Serine-Rich protein 1 |
233 |
PPP1R13L | oncoprotein | 5 | 1.000 | 0 | Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) SH3_9 (PF14604, IPR001452): Variant SH3 domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
234 |
PRLR | oncoprotein | 2 | 0 | 0 | EpoR_lig-bind (PF09067, IPR015152): Erythropoietin receptor, ligand binding fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain |
235 |
PSMC5 | protein found in more fusions | 24 | 0.308 | 68.215 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) Laminin_II (PF06009, IPR010307): Laminin Domain II RILP (PF11461, IPR021563): Rab interacting lysosomal protein AAA_16 (PF13191): AAA ATPase domain |
236 |
PSME3 | protein found in more fusions | 13 | 0.379 | 129.625 | PA28_alpha (PF02251, IPR003185): Proteasome activator pa28 alpha subunit PA28_beta (PF02252, IPR003186): Proteasome activator pa28 beta subunit |
237 |
PTMA | oncoprotein | 12 | 0.439 | 17.958 | Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family |
238 |
PTMS | interactor | 6 | 0.533 | 1.885 | Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family U79_P34 (PF03064, IPR004138): HSV U79 / HCMV P34 |
239 |
PTOV1 | interactor | 1 | 0 | 0 | Med25 (PF11232, IPR021394): Mediator complex subunit 25 PTOV activation and synapsin 2 |
240 |
PTTG1 | oncoprotein | 12 | 0.309 | 45.403 | Securin (PF04856, IPR006940): Securin sister-chromatid separation inhibitor |
241 |
PYGO2 | interactor | 5 | 0.667 | 0.509 | PHD (PF00628, IPR019787, SM00249): PHD-finger |
242 |
RAD23A | oncoprotein | 11 | 0.533 | 8.324 | UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
243 |
RARA | oncoprotein | 36 | 0.271 | 185.943 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
244 |
RBBP4 | oncoprotein | 28 | 0.413 | 64.615 | eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex |
245 |
RBBP7 | suppressor | 19 | 0.450 | 47.399 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex |
246 |
REL | oncoprotein | 14 | 0.385 | 44.817 | RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
247 |
RELA | oncoprotein | 66 | 0.228 | 824.386 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
248 |
RERE | oncoprotein | 8 | 0.429 | 40.980 | Atrophin-1 (PF03154, IPR002951): Atrophin-1 family BAH (PF01426, IPR001025, SM00439): BAH domain ELM2 (PF01448, IPR000949): ELM2 domain POPLD (PF08170, IPR012590): POPLD (NUC188) domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain GATA (PF00320, IPR000679, SM00401): GATA zinc finger |
249 |
RNPS1 | interactor | 10 | 0.178 | 45.048 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457) Macoilin (PF09726, IPR019130): Transmembrane protein |
250 |
RPA2 | oncoprotein | 21 | 0.286 | 148.933 | RPA_C (PF08784, IPR014892): Replication protein A C terminal tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2 |
251 |
RPL10 | suppressor | 15 | 0.171 | 147.936 | Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e |
252 |
RPS6KA1 | oncoprotein | 8 | 0.536 | 6.502 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
253 |
RPS6KA2 | suppressor | 7 | 0.800 | 1.119 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
254 |
RPS6KA3 | interactor | 7 | 0.524 | 7.387 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
255 |
RPS6KA5 | interactor | 14 | 0.341 | 40.341 | Choline_kinase (PF01633): Choline/ethanolamine kinase Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein |
256 |
RSF1 | oncoprotein | 6 | 0.133 | 8.738 | DDT (PF02791, IPR004022, SM00571): DDT domain DTHCT (PF08070, IPR012542): DTHCT (NUC029) region DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) PHD (PF00628, IPR019787, SM00249): PHD-finger UPF0239 (PF06783, IPR009621): Uncharacterised protein family (UPF0239) TFIIE-A_C (PF11521, IPR021600): C-terminal general transcription factor TFIIE alpha Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal WHIM1 (PF15612, IPR028942): WSTF, HB1, Itc1p, MBD9 motif 1 |
257 |
RUNX1 | suppressor | 29 | 0.415 | 87.884 | Runt (PF00853, IPR013524): Runt domain RunxI (PF08504, IPR013711): Runx inhibition domain DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037) |
258 |
RUNX2 | suppressor | 17 | 0.596 | 9.597 | DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) Runt (PF00853, IPR013524): Runt domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) DUF2722 (PF10846, IPR021216): Protein of unknown function (DUF2722) |
259 |
RUVBL1 | oncoprotein | 17 | 0.383 | 23.635 | TIP49 (PF06068, IPR010339): TIP49 C-terminus |
260 |
SERTAD1 | interactor | 6 | 0.533 | 4.019 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal SERTA (PF06031, IPR009263): SERTA motif |
261 |
SETD1A | interactor | 7 | 0.571 | 8.095 | E7 (PF00527, IPR000148): E7 protein, Early protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET (PF00856, IPR001214, SM00317): SET domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit N-SET (PF11764, IPR024657): COMPASS (Complex proteins associated with Set1p) component N DUF4632 (PF15451, IPR027952): Domain of unknown function (DUF4632) DUF4667 (PF15700, IPR031426): Domain of unknown function (DUF4667) PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
262 |
SH3GL1 | oncoprotein | 5 | 0.667 | 0.883 | BAR (PF03114, IPR004148, SM00721): BAR domain PhnG (PF06754, IPR009609): Phosphonate metabolism protein PhnG SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
263 |
SMAD1 | interactor | 25 | 0.348 | 101.343 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
264 |
SMAD2 | suppressor | 48 | 0.271 | 349.814 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
265 |
SMAD3 | oncoprotein | 70 | 0.244 | 708.294 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
266 |
SMAD4 | suppressor | 40 | 0.289 | 220.433 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
267 |
SMARCA2 | suppressor | 32 | 0.401 | 95.188 | DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168) DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain YL1 (PF05764, IPR008895): YL1 nuclear protein BRK (PF07533, IPR006576, SM00592): BRK domain DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
268 |
SMARCA4 | suppressor | 62 | 0.234 | 626.499 | DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain BRK (PF07533, IPR006576, SM00592): BRK domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065) SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
269 |
SMARCB1 | suppressor | 30 | 0.337 | 115.020 | SNF5 (PF04855, IPR006939): SNF5 / SMARCB1 / INI1 |
270 |
SNAI1 | oncoprotein | 13 | 0.564 | 13.314 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger |
271 |
SND1 | interactor | 10 | 0.400 | 27.179 | TUDOR (PF00567, IPR002999, SM00333): Tudor domain SNase (PF00565, IPR016071, SM00318): Staphylococcal nuclease homologue |
272 |
SNIP1 | interactor | 8 | 0.607 | 39.950 | FHA (PF00498, IPR000253, SM00240): FHA domain MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 FAM176 (PF14851): FAM176 family |
273 |
SP1 | protein found in more fusions | 66 | 0.242 | 864.807 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
274 |
SP3 | interactor | 12 | 0.773 | 2.152 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
275 |
SRC | oncoprotein | 29 | 0.267 | 183.425 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
276 |
SRCAP | interactor | 7 | 0.667 | 1.593 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif HSA (PF07529, IPR014012, SM00573): HSA RXT2_N (PF08595, IPR013904): RXT2-like, N-terminal SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DBINO (PF13892, IPR020838): DNA-binding domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal |
277 |
SREBF1 | interactor | 18 | 0.382 | 60.441 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor |
278 |
SREBF2 | protein found in more fusions | 17 | 0.400 | 54.349 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit |
279 |
SRF | interactor | 21 | 0.342 | 38.602 | SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain) |
280 |
SS18L1 | oncoprotein | 10 | 0.611 | 3.134 | DUF1313 (PF07011, IPR009741): Protein of unknown function (DUF1313) SSXT (PF05030, IPR007726): SSXT protein (N-terminal region) |
281 |
STAT1 | suppressor | 26 | 0.387 | 98.815 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain STAT1_TAZ2bind (PF12162, IPR022752): STAT1 TAZ2 binding domain |
282 |
STAT2 | oncoprotein | 9 | 0.472 | 11.032 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain STAT2_C (PF12188, IPR022756): Signal transducer and activator of transcription 2 C terminal |
283 |
STAT3 | suppressor | 42 | 0.294 | 248.691 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain |
284 |
STAT6 | oncoprotein | 13 | 0.462 | 19.392 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain STAT6_C (PF14596, IPR028187): STAT6 C-terminal |
285 |
SYMPK | interactor | 6 | 0.133 | 12.587 | HEAT (PF02985, IPR000357): HEAT repeat DUF3453 (PF11935, IPR021850): Domain of unknown function (DUF3453) Symplekin_C (PF12295, IPR022075): Symplekin tight junction protein C terminal Cohesin_HEAT (PF12765, IPR026003): HEAT repeat associated with sister chromatid cohesion |
286 |
TACC2 | interactor | 4 | 0.833 | 0.100 | TACC (PF05010, IPR007707): Transforming acidic coiled-coil-containing protein (TACC) |
287 |
TAF6L | interactor | 4 | 0.833 | 0.286 | TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain TAF (PF02969, IPR004823, SM00803): TATA box binding protein associated factor (TAF) |
288 |
TBP | interactor | 40 | 0.316 | 217.480 | TBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal |
289 |
TBX21 | oncoprotein | 3 | 1.000 | 0 | T-box (PF00907, IPR001699, SM00425): T-box T-box_assoc (PF16176, IPR032385): T-box transcription factor-associated |
290 |
TCF12 | oncoprotein | 10 | 0.750 | 1.866 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
291 |
TCF3 | suppressor | 15 | 0.473 | 12.723 | CDC45 (PF02724, IPR003874): CDC45-like protein HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682) |
292 |
TDG | interactor | 17 | 0.419 | 49.808 | Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein UDG (PF03167, IPR005122, SM00986): Uracil DNA glycosylase superfamily |
293 |
TFAP2B | interactor | 5 | 0.500 | 2.843 | TF_AP-2 (PF03299, IPR013854): Transcription factor AP-2 |
294 |
TFDP1 | oncoprotein | 9 | 0.528 | 7.542 | DP (PF08781, IPR014889, SM01138): Transcription factor DP E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain |
295 |
TGS1 | interactor | 4 | 0.833 | 0.166 | DinI (PF06183, IPR010391): DinI-like family DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Methyltransf_15 (PF09445, IPR019012): RNA cap guanine-N2 methyltransferase Presenilin (PF01080, IPR001108): Presenilin |
296 |
TLE3 | interactor | 4 | 0.667 | 0.467 | TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
297 |
TLR2 | interactor | 3 | 1.000 | 0 | LRRCT (PF01463, IPR000483, SM00082): Leucine rich repeat C-terminal domain TIR (PF01582, IPR000157, SM00255): TIR domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat |
298 |
TNRC6B | interactor | 5 | 0 | 12.855 | DUF1421 (PF07223, IPR010820): Protein of unknown function (DUF1421) Totivirus_coat (PF05518, IPR008871): Totivirus coat protein Ago_hook (PF10427, IPR019486): Argonaute hook DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) TNRC6-PABC_bdg (PF16608, IPR032226): TNRC6-PABC binding domain RRM_occluded (PF16842, IPR031766): Occluded RNA-recognition motif |
299 |
TP53 | suppressor | 107 | 0.165 | 2871.936 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
300 |
TP73 | suppressor | 26 | 0.393 | 84.643 | P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) |
301 |
TRERF1 | interactor | 5 | 0.600 | 1.139 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal ELM2 (PF01448, IPR000949): ELM2 domain Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF2681 (PF10883, IPR020274): Protein of unknown function (DUF2681) MCRS_N (PF13325, IPR025999): N-terminal region of micro-spherule protein zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
302 |
TRIM28 | protein found in more fusions | 34 | 0.254 | 565.637 | ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2 |
303 |
TRIP4 | interactor | 13 | 0.564 | 9.361 | ASCH (PF04266, IPR007374, SM01022): ASCH domain UxaC (PF02614, IPR003766): Glucuronate isomerase zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type |
304 |
TXNDC11 | interactor | 3 | 0.667 | 0.667 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1 Thioredoxin (PF00085, IPR013766): Thioredoxin Thioredoxin_6 (PF13848): Thioredoxin-like domain |
305 |
UBE2D1 | interactor | 14 | 0.474 | 18.130 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
306 |
UBE2I | interactor | 69 | 0.190 | 1095.039 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
307 |
UBE2S | interactor | 9 | 0.786 | 4.540 | ALF (PF03752, IPR005506): Short repeats of unknown function UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
308 |
UBE2U | interactor | 4 | 0.500 | 2.305 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme efb-c (PF12199, IPR021033): Extracellular fibrinogen binding protein C terminal TMEM154 (PF15102, IPR028064): TMEM154 protein family |
309 |
VDR | suppressor | 36 | 0.329 | 149.961 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
310 |
WDR5 | interactor | 25 | 0.290 | 264.691 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
311 |
WRN | oncoprotein | 12 | 0.473 | 19.232 | DNA_pol_A_exo1 (PF01612, IPR002562, SM00474): 3'-5' exonuclease DEAD (PF00270, IPR011545): DEAD/DEAH box helicase HRDC (PF00570, IPR002121, SM00341): HRDC domain Laminin_II (PF06009, IPR010307): Laminin Domain II RQC (PF09382, IPR018982, SM00956): RQC domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain HTH_40 (PF14493, IPR029491): Helix-turn-helix domain RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding |
312 |
XAF1 | suppressor | 3 | 1.000 | 0 | Sgf11 (PF08209, IPR013246): Sgf11 (transcriptional regulation protein) zf-dskA_traR (PF01258, IPR000962): Prokaryotic dksA/traR C4-type zinc finger PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein zf-CpG_bind_C (PF12269, IPR022056): CpG binding protein zinc finger C terminal domain PL48 (PF15903, IPR031780): Filopodia upregulated, FAM65 |
313 |
XRCC6 | oncoprotein | 36 | 0.267 | 252.876 | Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain SAP (PF02037, IPR003034, SM00513): SAP domain |
314 |
YY1 | protein found in more fusions | 29 | 0.368 | 80.354 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail |
315 |
ZBTB2 | interactor | 7 | 0.667 | 2.664 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-met (PF12874): Zinc-finger of C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
316 |
ZCCHC12 | interactor | 2 | 1.000 | 0 | PNMA (PF14893, IPR026523): PNMA zf-C2H2_10 (PF16588, IPR001878): C2H2 zinc-finger |
317 |
ZEB1 | interactor | 9 | 0.528 | 3.656 | CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27 zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding GET2 (PF08690, IPR028143): GET complex subunit GET2 Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Homeobox (PF00046, IPR001356, SM00389): Homeobox domain zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
318 |
ZNF639 | interactor | 1 | 0 | 0 | CarbpepA_inh (PF02977, IPR004231): Carboxypeptidase A inhibitor zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain |