Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins CHD3 (from a repository: Sat Dec 3 13:20:20 2016)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 146 The number (and %) of the onco-proteins 50 (34.25 %) The number (and %) of the tumor suppressors 24 (16.44 %) Total number of binary PPIs (saturation %) 1000 (9.45 %) The number (and %) of affected PPIs 146 (14.60 %) The number of possible different fusions 34 PPI diameter 2 PPI radius 1 The average degree of PPI 12.658 Assortativity coefficient -0.3041 The network average Clustering coefficient 0.565 The number (and %) of a zero Clustering coefficients 4 (2.74 %) The number (and %) of a zero Betweenness Centrality 26 (17.81 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: CHD3	All fusions : BF932643;
Proteins found in more fusions	SAT1 (see 5 fusions); CTBP1 (see 2 fusions); LUC7L2 (see 2 fusions); PUF60 (see 2 fusions); TRIM28 (see 1 fusions); GSK3B (see 1 fusions); KPNB1 (see 2 fusions); HSF1 (see 3 fusions); BCL6 (see 2 fusions); CREB1 (see 2 fusions); IVNS1ABP (see 2 fusions); UBA3 (see 1 fusions); SERBP1 (see 1 fusions); IKZF1 (see 1 fusions); KMT2A (see 16 fusions); AIMP2 (see 1 fusions); IMMT (see 4 fusions); MCM2 (see 1 fusions); CTTN (see 1 fusions); HTT (see 1 fusions); KDM1A (see 2 fusions); CSNK2A1 (see 1 fusions); CHD3 (see 1 fusions); TSC22D1 (see 5 fusions); UBC (see 1 fusions); MBD2 (see 1 fusions); DDX5 (see 1 fusions); PRPF40A (see 2 fusions); UROD (see 1 fusions); TNNT1 (see 1 fusions); CHD4 (see 6 fusions); TP53 (see 3 fusions); SNW1 (see 1 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	CHD3	parental protein	146	0.075	13797.187	CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086) DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087) DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DUF2956 (PF11169, IPR021339): Protein of unknown function (DUF2956) FAM176 (PF14851): FAM176 family
2	ADH5	interactor	5	1.000	0	ADH_N (PF08240, IPR013154): Alcohol dehydrogenase GroES-like domain ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase
3	AIMP2	suppressor	8	0.333	8.019	GST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain GST_C_3 (PF14497, IPR004046): Glutathione S-transferase, C-terminal domain AIMP2_LysRS_bd (PF16780, IPR031889): AIMP2 lysyl-tRNA synthetase binding domain
4	ATPIF1	interactor	2	1.000	0	DivIC (PF04977, IPR007060): Septum formation initiator IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP
5	BARD1	suppressor	18	0.287	64.694	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) zf-RING_6 (PF14835): zf-RING of BARD1-type protein BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
6	BCL6	oncoprotein	11	0.644	4.234	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding DZR (PF12773, IPR025874): Double zinc ribbon zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
7	BHLHE40	interactor	9	0.643	3.432	Hairy_orange (PF07527, IPR003650): Hairy Orange HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
8	BMI1	oncoprotein	20	0.281	71.467	zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
9	C4orf17	interactor	2	1.000	0	SPATIAL (PF15256): SPATIAL
10	CASP6	interactor	4	0.667	1.000	Peptidase_C14 (PF00656, IPR011600): Caspase domain
11	CASP8	suppressor	7	0.467	5.283	DED (PF01335, IPR001875, SM00031): Death effector domain Peptidase_C14 (PF00656, IPR011600): Caspase domain
12	CCDC8	interactor	17	0.333	41.603	Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA
13	CD2BP2	interactor	6	0.600	2.617	GYF (PF02213, IPR003169, SM00444): GYF domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region Hist_rich_Ca-bd (PF10529, IPR019552): Histidine-rich Calcium-binding repeat region
14	CDK2AP1	suppressor	15	0.990	0.111	CDK2AP (PF09806, IPR019187): Cyclin-dependent kinase 2-associated protein
15	CHD4	oncoprotein	38	0.356	203.669	CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27 CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain DTHCT (PF08070, IPR012542): DTHCT (NUC029) region DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086) DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087) PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain FAM176 (PF14851): FAM176 family Coilin_N (PF15862, IPR031722): Coilin N-terminus
16	CHD6	interactor	2	1.000	0	CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain BORG_CEP (PF14957, IPR029273): Cdc42 effector
17	CPE	interactor	2	1.000	0	Peptidase_M14 (PF00246, IPR000834, SM00631): Zinc carboxypeptidase CarboxypepD_reg (PF13620): Carboxypeptidase regulatory-like domain
18	CPSF1	interactor	6	0.467	4.950	CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term HPS3_N (PF14761, IPR029437): Hermansky-Pudlak syndrome 3
19	CRCT1	interactor	4	0.667	0.619	NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family
20	CREB1	oncoprotein	16	0.467	24.635	bZIP_1 (PF00170, IPR004827): bZIP transcription factor pKID (PF02173, IPR003102): pKID domain DUF4988 (PF16378, IPR032149): Domain of unknown function
21	CSNK2A1	oncoprotein	25	0.293	111.644	Pkinase (PF00069, IPR000719): Protein kinase domain
22	CSTF2	interactor	5	0.600	2.833	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C (PF14304, IPR026896): Transcription termination and cleavage factor C-terminal CSTF2_hinge (PF14327, IPR025742): Hinge domain of cleavage stimulation factor subunit 2
23	CTBP1	protein found in more fusions	16	0.419	24.088	2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D
24	CTTN	oncoprotein	6	0.600	3.333	FadA (PF09403, IPR018543): Adhesion protein FadA HS1_rep (PF02218, IPR003134): Repeat in HS1/Cortactin SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
25	DDX5	oncoprotein	18	0.324	48.210	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
26	ENO1	oncoprotein	11	0.327	24.738	Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
27	FABP4	interactor	2	1.000	0	Lipocalin (PF00061, IPR000566): Lipocalin / cytosolic fatty-acid binding protein family
28	FAM134A	interactor	1	0	0	INSIG (PF07281, IPR025929): Insulin-induced protein (INSIG) Reticulon (PF02453, IPR003388): Reticulon
29	FBP2	interactor	2	0	0	FBPase (PF00316, IPR000146): Fructose-1-6-bisphosphatase, N-terminal domain
30	FUBP1	oncoprotein	8	0.464	7.938	DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897) KH_1 (PF00013, IPR004088, SM00322): KH domain CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
31	GADD45A	suppressor	6	0.700	0.889	Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
32	GATAD2A	interactor	18	0.876	3.440	DUF2299 (PF10061, IPR018747): Uncharacterized conserved protein (DUF2299) GATA (PF00320, IPR000679, SM00401): GATA zinc finger DUF3123 (PF11321, IPR021470): Protein of unknown function (DUF3123) P66_CC (PF16563, IPR032346): Coiled-coil and interaction region of P66A and P66B with MBD2
33	GATAD2B	interactor	21	0.743	11.332	DUF1178 (PF06676, IPR009562): Protein of unknown function (DUF1178) zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger GATA (PF00320, IPR000679, SM00401): GATA zinc finger DUF3619 (PF12279, IPR022064): Protein of unknown function (DUF3619) P66_CC (PF16563, IPR032346): Coiled-coil and interaction region of P66A and P66B with MBD2
34	GIT1	interactor	10	0.250	21.900	ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family GIT_SHD (PF08518, IPR013724, SM00555): Spa2 homology domain (SHD) of GIT GIT1_C (PF12205, IPR022018): G protein-coupled receptor kinase-interacting protein 1 C term Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) FlxA (PF14282, IPR025577): FlxA-like protein GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
35	GPS2	oncoprotein	6	0.667	1.302	G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor
36	GSK3B	suppressor	10	0.444	13.309	Pkinase (PF00069, IPR000719): Protein kinase domain
37	HABP4	interactor	4	0.833	0.143	HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
38	HDAC1	suppressor	52	0.299	402.627	FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
39	HDAC2	suppressor	49	0.316	327.138	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
40	HDAC3	suppressor	15	0.308	26.123	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
41	HIC1	suppressor	9	0.536	3.704	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger
42	HIST1H2BB	interactor	5	0.600	2.250	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
43	HIST1H3A	interactor	22	0.395	65.244	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
44	HSD17B10	interactor	4	0.667	1.500	adh_short (PF00106, IPR002198): short chain dehydrogenase
45	HSF1	protein found in more fusions	7	0.867	0.271	DUF247 (PF03140, IPR004158): Plant protein of unknown function Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding
46	HSPH1	oncoprotein	2	1.000	0	HSP70 (PF00012, IPR013126): Hsp70 protein SICA_alpha (PF12887, IPR024290): SICA extracellular alpha domain
47	HTT	protein found in more fusions	9	0.464	8.456	HEAT (PF02985, IPR000357): HEAT repeat SPX (PF03105, IPR004331): SPX domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF3652 (PF12372, IPR024613): Huntingtin protein region Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats
48	IK	interactor	8	0.714	2.015	Lsm_interact (PF05391, IPR008669): Lsm interaction motif RED_C (PF07807, IPR012492): RED-like protein C-terminal region RED_N (PF07808, IPR012916): RED-like protein N-terminal region PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
49	IKZF1	suppressor	12	0.655	4.576	Desulfoferrod_N (PF06397, IPR004462): Desulfoferrodoxin, N-terminal domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-met (PF12874): Zinc-finger of C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger
50	IMMT	protein found in more fusions	12	0.255	29.217	Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
51	IVNS1ABP	protein found in more fusions	6	0.500	2.905	BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
52	JUN	oncoprotein	17	0.367	32.637	bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor
53	KDM1A	protein found in more fusions	32	0.357	177.864	Amino_oxidase (PF01593, IPR002937): Flavin containing amine oxidoreductase CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain SWIRM (PF04433, IPR007526): SWIRM domain DUF4298 (PF14131, IPR025384): Domain of unknown function (DUF4298)
54	KDM5B	interactor	11	0.873	1.768	ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase JmjN (PF02375, IPR003349, SM00545): jmjN domain PHD (PF00628, IPR019787, SM00249): PHD-finger PLU-1 (PF08429, IPR013637): PLU-1-like protein FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger Rubredoxin (PF00301, IPR024935): Rubredoxin zf-C5HC2 (PF02928, IPR004198): C5HC2 zinc finger Lipoprotein_20 (PF13942, IPR025262): YfhG lipoprotein
55	KIF15	interactor	2	1.000	0	Bcr-Abl_Oligo (PF09036, IPR015123): Bcr-Abl oncoprotein oligomerisation domain DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) SlyX (PF04102, IPR007236): SlyX STE (PF02200, IPR003120, SM00424): STE like transcription factor Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding FlxA (PF14282, IPR025577): FlxA-like protein HMMR_C (PF15908, IPR031794): Hyaluronan mediated motility receptor C-terminal
56	KMT2A	oncoprotein	19	0.523	28.671	AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 SET (PF00856, IPR001214, SM00317): SET domain zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain zf-HC5HC2H (PF13771): PHD-like zinc-binding domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
57	KPNB1	protein found in more fusions	14	0.449	21.356	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat HEAT (PF02985, IPR000357): HEAT repeat IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H CLASP_N (PF12348, IPR024395): CLASP N terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 HEAT_EZ (PF13513): HEAT-like repeat
58	LGR4	interactor	9	0.321	11.967	7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat
59	LRIF1	interactor	14	0.256	43.221	LRIF1 (PF15741, IPR026191): Ligand-dependent nuclear receptor-interacting factor 1
60	LUC7L2	protein found in more fusions	17	0.233	66.115	LUC7 (PF03194, IPR004882): LUC7 N_terminus Paramyxo_ncap (PF00973, IPR002021): Paramyxovirus nucleocapsid protein Methyltransf_32 (PF13679, IPR025714): Methyltransferase domain
61	MAFG	oncoprotein	3	1.000	0	bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor ThrE_2 (PF12821, IPR024528): Threonine/Serine exporter, ThrE
62	MAN2A2	interactor	4	0.500	1.186	Alpha-mann_mid (PF09261, IPR015341, SM00872): Alpha mannosidase middle domain Glyco_hydro_38 (PF01074, IPR000602): Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C (PF07748, IPR011682): Glycosyl hydrolases family 38 C-terminal domain
63	MBD2	oncoprotein	20	0.825	5.446	API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5) Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein MBD (PF01429, IPR001739, SM00391): Methyl-CpG binding domain MBD_C (PF14048, IPR025884): C-terminal domain of methyl-CpG binding protein 2 and 3 MBDa (PF16564, IPR032343): p55-binding region of Methyl-CpG-binding domain proteins MBD
64	MBD3	interactor	30	0.510	68.915	DUF2201_N (PF13203, IPR025154): Putative metallopeptidase domain
65	MBD3L1	interactor	16	0.950	0.951	MBD_C (PF14048, IPR025884): C-terminal domain of methyl-CpG binding protein 2 and 3 MBDa (PF16564, IPR032343): p55-binding region of Methyl-CpG-binding domain proteins MBD
66	MCM2	oncoprotein	21	0.205	115.036	AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
67	METAP2	oncoprotein	2	1.000	0	Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24 SRP72 (PF08492, IPR013699): SRP72 RNA-binding domain TSGP1 (PF07771, IPR011694): Tick salivary peptide group 1
68	MOV10	interactor	16	0.267	56.706	AAA_12 (PF13087): AAA domain AAA_30 (PF13604): AAA domain
69	MTA1	oncoprotein	30	0.494	88.821	BAH (PF01426, IPR001025, SM00439): BAH domain ELM2 (PF01448, IPR000949): ELM2 domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain GATA (PF00320, IPR000679, SM00401): GATA zinc finger
70	MTA2	interactor	31	0.495	89.715	BAH (PF01426, IPR001025, SM00439): BAH domain ELM2 (PF01448, IPR000949): ELM2 domain Resolvase (PF00239, IPR006119, SM00857): Resolvase, N terminal domain DDA1 (PF10172, IPR018276): Det1 complexing ubiquitin ligase Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain GATA (PF00320, IPR000679, SM00401): GATA zinc finger
71	MTA3	oncoprotein	22	0.680	25.295	BAH (PF01426, IPR001025, SM00439): BAH domain ELM2 (PF01448, IPR000949): ELM2 domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain GATA (PF00320, IPR000679, SM00401): GATA zinc finger
72	MX1	interactor	4	1.000	0	Dynamin_M (PF01031, IPR000375): Dynamin central region GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
73	MYB	oncoprotein	8	0.536	4.886	Cmyb_C (PF09316, IPR015395): C-myb, C-terminal LMSTEN (PF07988, IPR012642): LMSTEN motif Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
74	NAB2	oncoprotein	3	1.000	0	NCD1 (PF04904, IPR006988): NAB conserved region 1 (NCD1) NCD2 (PF04905, IPR006989): NAB conserved region 2 (NCD2)
75	NEFL	interactor	5	0.500	1.456	Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region NOA36 (PF06524, IPR010531): NOA36 protein BORG_CEP (PF14957, IPR029273): Cdc42 effector
76	NR1H2	oncoprotein	5	0.600	0.851	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
77	NR4A1	suppressor	5	0.800	0.254	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
78	NXF1	interactor	19	0.268	67.037	NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat
79	OTUD6B	interactor	2	1.000	0	Cep57_MT_bd (PF06657, IPR024957): Centrosome microtubule-binding domain of Cep57 Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family HemY_N (PF07219, IPR010817): HemY protein N-terminus OTU (PF02338, IPR003323): OTU-like cysteine protease DUF2335 (PF10097, IPR019284): Predicted membrane protein (DUF2335)
80	PAICS	interactor	3	1.000	0	AIRC (PF00731, IPR000031, SM01001): AIR carboxylase SAICAR_synt (PF01259, IPR028923): SAICAR synthetase
81	PCMT1	interactor	6	0.600	3.022	PCMT (PF01135, IPR000682): Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
82	PCNT	interactor	7	0.667	5.571	Caldesmon (PF02029, IPR006018): Caldesmon CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) DUF1640 (PF07798, IPR024461): Protein of unknown function (DUF1640) DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) DUF883 (PF05957, IPR010279): Bacterial protein of unknown function (DUF883) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family SlyX (PF04102, IPR007236): SlyX Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14 Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5 Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 PACT_coil_coil (PF10495, IPR019528): Pericentrin-AKAP-450 domain of centrosomal targeting protein zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein PP2C_C (PF07830, IPR012911, SM00332): Protein serine/threonine phosphatase 2C, C-terminal domain Tho2 (PF11262, IPR021418): Transcription factor/nuclear export subunit protein 2 Colicin-DNase (PF12639, IPR024622): DNase/tRNase domain of colicin-like bacteriocin CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit DUF4239 (PF14023, IPR025333): Protein of unknown function (DUF4239) WD40_alt (PF14077, IPR026987): Alternative WD40 repeat motif FlxA (PF14282, IPR025577): FlxA-like protein FAM184 (PF15665): Family with sequence similarity 184, A and B HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
83	PHF20L1	interactor	13	0.833	3.840	MBT (PF02820, IPR004092, SM00561): mbt repeat PHD (PF00628, IPR019787, SM00249): PHD-finger U79_P34 (PF03064, IPR004138): HSV U79 / HCMV P34 DUF3776 (PF12618, IPR022255): Protein of unknown function (DUF3776) CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal DUF4537 (PF15057, IPR032770): Domain of unknown function (DUF4537) PEHE (PF15275, IPR029332): PEHE domain EFTUD2 (PF16004, IPR031950): 116 kDa U5 small nuclear ribonucleoprotein component N-terminus PHD20L1_u1 (PF16660): PHD finger protein 20-like protein 1
84	PHF6	suppressor	8	0.536	5.826	zf-HC5HC2H (PF13771): PHD-like zinc-binding domain YqfQ (PF14181, IPR025571): YqfQ-like protein
85	PIAS4	interactor	22	0.299	99.573	CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain SAP (PF02037, IPR003034, SM00513): SAP domain zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain
86	PLK4	interactor	4	0.667	1.000	ABC1 (PF03109, IPR004147): ABC1 family Pkinase (PF00069, IPR000719): Protein kinase domain POLO_box (PF00659, IPR000959): POLO box duplicated region DUF4520 (PF15016, IPR027865): Domain of unknown function (DUF4520)
87	PRG2	interactor	1	0	0	Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain DUF4628 (PF15429, IPR027851): Domain of unknown function (DUF4628)
88	PRPF40A	protein found in more fusions	12	0.473	13.395	FF (PF01846, IPR002713, SM00441): FF domain MCR_alpha (PF02249, IPR009047): Methyl-coenzyme M reductase alpha subunit, C-terminal domain Transformer (PF06495, IPR010519): Fruit fly transformer protein WW (PF00397, IPR001202, SM00456): WW domain YqzE (PF14038, IPR025622): YqzE-like protein SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6 SRRM_C (PF15230, IPR029360): Serine/arginine repetitive matrix protein C-terminus SOBP (PF15279, IPR026092): Sine oculis-binding protein IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
89	PSMD14	interactor	3	0.667	0.667	JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
90	PSME1	interactor	6	0.500	3.467	PA28_alpha (PF02251, IPR003185): Proteasome activator pa28 alpha subunit PA28_beta (PF02252, IPR003186): Proteasome activator pa28 beta subunit RNase_H2-Ydr279 (PF09468, IPR019024): Ydr279p protein family (RNase H2 complex component)
91	PTN	oncoprotein	15	0.209	54.133	PTN_MK_C (PF01091, IPR020090): PTN/MK heparin-binding protein family, C-terminal domain PTN_MK_N (PF05196, IPR020089): PTN/MK heparin-binding protein family, N-terminal domain
92	PTPRS	interactor	2	1.000	0	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase Ig_3 (PF13927): Immunoglobulin domain
93	PUF60	protein found in more fusions	11	0.356	14.787	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Titin_Z (PF09042, IPR015129): Titin Z TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
94	RAD21	oncoprotein	13	0.372	29.725	Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
95	RAD51	interactor	8	0.571	3.033	Rad51 (PF08423, IPR013632): Rad51 HHH_5 (PF14520): Helix-hairpin-helix domain
96	RBBP4	oncoprotein	35	0.445	111.925	eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
97	RBBP7	suppressor	34	0.462	97.976	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
98	RGS2	oncoprotein	3	0.667	1.000	RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
99	RNF2	interactor	27	0.397	86.000	zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
100	RPL10	suppressor	12	0.394	21.918	Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
101	RPL29	interactor	3	1.000	0	BRF1 (PF07741, IPR011665): Brf1-like TBP-binding domain Ribosomal_L29e (PF01779, IPR002673): Ribosomal L29e protein family
102	SAFB	suppressor	5	0.600	2.100	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP (PF02037, IPR003034, SM00513): SAP domain Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
103	SAT1	protein found in more fusions	8	0.429	5.460	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
104	SATB1	oncoprotein	14	0.440	24.953	CUT (PF02376, IPR003350, SM01109): CUT domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DUF3371 (PF11851, IPR021802): Domain of unknown function (DUF3371) ULD (PF16534, IPR032392): Ubiquitin-like oligomerisation domain of SATB CUTL (PF16557, IPR032355): CUT1-like DNA-binding domain of SATB SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
105	SDCCAG3	interactor	4	0.500	2.400	GA (PF01468, IPR002988, SM00844): GA module TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
106	SERBP1	protein found in more fusions	8	0.619	3.016	HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
107	SERF2	interactor	1	0	0	4F5 (PF04419, IPR007513): 4F5 protein family
108	SGSM2	interactor	2	1.000	0	Cullin_binding (PF03556, IPR005176): Cullin binding RUN (PF02759, IPR004012, SM00593): RUN domain RabGAP-TBC (PF00566, IPR000195, SM00164): Rab-GTPase-TBC domain zf-BED (PF02892, IPR003656, SM00614): BED zinc finger DUF3548 (PF12068, IPR021935): Domain of unknown function (DUF3548)
109	SHMT2	interactor	6	0.400	6.733	SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase
110	SIN3A	oncoprotein	32	0.379	131.382	Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein
111	SIRT1	suppressor	18	0.368	42.224	DUF592 (PF04574, IPR007654): Protein of unknown function (DUF592) SIR2 (PF02146, IPR003000): Sir2 family TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
112	SIRT6	suppressor	11	0.655	5.402	SIR2 (PF02146, IPR003000): Sir2 family TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
113	SKIL	suppressor	7	0.667	1.093	c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain DUF489 (PF04356, IPR007451): Protein of unknown function (DUF489) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family DUF2115 (PF09888, IPR019215): Uncharacterized protein conserved in archaea (DUF2115)
114	SLC27A6	interactor	2	1.000	0	AMP-binding (PF00501, IPR000873): AMP-binding enzyme AMP-binding_C (PF13193, IPR025110): AMP-binding enzyme C-terminal domain
115	SMARCA2	suppressor	15	0.619	14.855	DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168) DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain YL1 (PF05764, IPR008895): YL1 nuclear protein BRK (PF07533, IPR006576, SM00592): BRK domain DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
116	SMARCA5	interactor	21	0.458	39.233	HAND (PF09110, IPR015194): HAND SLIDE (PF09111, IPR015195): SLIDE SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) DBINO (PF13892, IPR020838): DNA-binding domain RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
117	SMARCC2	interactor	18	0.399	44.230	GHMP_kinases_N (PF00288, IPR006204): GHMP kinases N terminal domain SWIRM (PF04433, IPR007526): SWIRM domain DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
118	SNRNP40	interactor	5	0.700	0.950	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
119	SNW1	protein found in more fusions	28	0.259	160.509	SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain
120	SOX2	oncoprotein	27	0.403	110.241	HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box SOXp (PF12336, IPR022097): SOX transcription factor
121	SRRT	interactor	9	0.361	13.327	ARS2 (PF04959, IPR007042): Arsenite-resistance protein 2 DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit Macoilin (PF09726, IPR019130): Transmembrane protein DUF3546 (PF12066, IPR021933): Domain of unknown function (DUF3546) DUF4187 (PF13821, IPR025239): Domain of unknown function (DUF4187)
122	SUMO1	interactor	15	0.407	28.285	Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
123	SUMO2	interactor	19	0.510	27.607	Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
124	TAF6	interactor	11	0.891	1.077	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain Spo0A_C (PF08769, IPR014879): Sporulation initiation factor Spo0A C terminal TAF (PF02969, IPR004823, SM00803): TATA box binding protein associated factor (TAF)
125	TAL1	oncoprotein	10	0.722	3.274	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG
126	TCERG1	interactor	6	0.800	0.841	FF (PF01846, IPR002713, SM00441): FF domain WW (PF00397, IPR001202, SM00456): WW domain Folliculin (PF11704, IPR021713): Vesicle coat protein involved in Golgi to plasma membrane transport DUF3807 (PF12720, IPR024526): Protein of unknown function (DUF3807) DUF3886 (PF13025, IPR024980): Protein of unknown function (DUF3886) Spore_coat_CotO (PF14153, IPR025439): Spore coat protein CotO FAM150 (PF15129, IPR029364): FAM150 family
127	THOC7	interactor	6	0.333	5.052	EcoEI_R_C (PF08463, IPR013670): EcoEI R protein C-terminal THOC7 (PF05615, IPR008501): Tho complex subunit 7 UPF0193 (PF05250, IPR007914): Uncharacterised protein family (UPF0193)
128	TNFRSF14	oncoprotein	3	0.667	0.333	Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like Hum_adeno_E3A (PF05393, IPR008652): Human adenovirus early E3A glycoprotein TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
129	TNNT1	protein found in more fusions	6	0.600	1.983	Troponin (PF00992, IPR001978): Troponin DUF4050 (PF13259, IPR025124): Protein of unknown function (DUF4050)
130	TP53	suppressor	51	0.200	621.045	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
131	TP73	suppressor	11	0.622	6.405	P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
132	TRIM28	protein found in more fusions	21	0.368	50.638	ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
133	TSC22D1	suppressor	6	0.600	1.127	SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region TSC22 (PF01166, IPR000580): TSC-22/dip/bun family ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
134	TSPAN6	interactor	2	1.000	0	Tetraspannin (PF00335, IPR018499): Tetraspanin family
135	TTR	interactor	3	1.000	0	Transthyretin (PF00576, IPR023416, SM00095): HIUase/Transthyretin family
136	TWIST1	oncoprotein	9	0.667	3.049	ACC_epsilon (PF13822, IPR032716): Acyl-CoA carboxylase epsilon subunit PRR20 (PF15708, IPR031439): Proline-rich protein family 20 FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
137	TXNDC9	interactor	4	0.500	1.667	Thioredoxin (PF00085, IPR013766): Thioredoxin DUF3619 (PF12279, IPR022064): Protein of unknown function (DUF3619)
138	UBA3	protein found in more fusions	3	1.000	0	E2_bind (PF08825, IPR014929): E2 binding domain ThiF (PF00899, IPR000594): ThiF family
139	UBC	protein found in more fusions	24	0.257	118.961	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
140	UBE2I	interactor	35	0.228	253.886	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
141	UROD	protein found in more fusions	5	0.500	0.933	URO-D (PF01208, IPR000257): Uroporphyrinogen decarboxylase (URO-D)
142	VIM	suppressor	44	0.103	689.100	Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
143	XRCC4	interactor	5	0.500	0.654	XRCC4 (PF06632, IPR010585): DNA double-strand break repair and V(D)J recombination protein XRCC4
144	YAE1D1	interactor	2	1.000	0	Yae1_N (PF09811, IPR019191): Essential protein Yae1, N terminal
145	ZHX1	interactor	18	0.368	42.433	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Homeobox (PF00046, IPR001356, SM00389): Homeobox domain Homez (PF11569, IPR024578): Homeodomain leucine-zipper encoding, Homez zf-C2H2_4 (PF13894): C2H2-type zinc finger TerB_C (PF15615, IPR028932): TerB-C domain
146	ZNF219	interactor	16	0.892	3.884	Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain PRIMA1 (PF16101): Proline-rich membrane anchor 1

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