1 |
CDK9 | parental protein | 178 | 0.067 | 20118.532 | Pkinase (PF00069, IPR000719): Protein kinase domain |
2 |
ACTL6A | interactor | 8 | 0.643 | 5.173 | Actin (PF00022, IPR004000, SM00268): Actin |
3 |
AFF1 | oncoprotein | 15 | 0.549 | 20.595 | AF-4 (PF05110, IPR007797): AF-4 proto-oncoprotein |
4 |
AFF3 | oncoprotein | 2 | 1.000 | 0 | AF-4 (PF05110, IPR007797): AF-4 proto-oncoprotein CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106 |
5 |
AFF4 | oncoprotein | 15 | 0.505 | 34.450 | AF-4 (PF05110, IPR007797): AF-4 proto-oncoprotein |
6 |
AIP | suppressor | 5 | 0.900 | 0.286 | FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat |
7 |
ANXA2 | interactor | 7 | 0.476 | 3.269 | Annexin (PF00191, IPR018502, SM00335): Annexin |
8 |
AR | oncoprotein | 26 | 0.247 | 149.281 | Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
9 |
ARID3B | interactor | 3 | 0.667 | 0.667 | ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain Phycobilisome (PF00502, IPR012128): Phycobilisome protein TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit |
10 |
ATM | oncoprotein | 20 | 0.327 | 60.693 | FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5 |
11 |
ATP1A1 | interactor | 4 | 1.000 | 0 | Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase Tetraspannin (PF00335, IPR018499): Tetraspanin family Cation_ATPase (PF13246): Cation transport ATPase (P-type) |
12 |
ATR | oncoprotein | 12 | 0.564 | 12.354 | FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1 THP2 (PF09432, IPR018557): Tho complex subunit THP2 TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat UME (PF08064, IPR012993, SM00802): UME (NUC010) domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) HEAT_EZ (PF13513): HEAT-like repeat SgrT (PF15894, IPR031767): Inhibitor of glucose uptake transporter SgrT |
13 |
ATRIP | interactor | 5 | 1.000 | 0 | Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like |
14 |
BARD1 | oncoprotein | 19 | 0.320 | 52.087 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) zf-RING_6 (PF14835): zf-RING of BARD1-type protein BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain |
15 |
BCL10 | oncoprotein | 6 | 0.600 | 2.667 | CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain |
16 |
BRCA1 | oncoprotein | 39 | 0.225 | 300.689 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT |
17 |
BRD4 | oncoprotein | 14 | 0.341 | 35.932 | Caldesmon (PF02029, IPR006018): Caldesmon Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region Stm1_N (PF09598, IPR019084): Stm1 SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain NAM-associated (PF14303, IPR029466): No apical meristem-associated C-terminal domain BET (PF17035, IPR027353): Bromodomain extra-terminal - transcription regulation BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4 |
18 |
BRDT | interactor | 2 | 1.000 | 0 | Allexi_40kDa (PF05549, IPR008398): Allexivirus 40kDa protein Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain DUF2079 (PF09852, IPR018650): Predicted membrane protein (DUF2079) Nop25 (PF09805, IPR019186): Nucleolar protein 12 (25kDa) Bromodomain (PF00439, IPR001487, SM00297): Bromodomain BET (PF17035, IPR027353): Bromodomain extra-terminal - transcription regulation BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4 |
19 |
CASK | interactor | 5 | 0.500 | 3.567 | L27 (PF02828, IPR014775, SM00569): L27 domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) Pkinase (PF00069, IPR000719): Protein kinase domain SH3_2 (PF07653, IPR011511): Variant SH3 domain Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase |
20 |
CCAR2 | suppressor | 13 | 0.423 | 20.918 | DREPP (PF05558, IPR008469): DREPP plasma membrane polypeptide IncA (PF04156, IPR007285): IncA protein RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 DBC1 (PF14443, IPR025954, SM01122): DBC1 S1-like (PF14444, IPR025223): S1-like |
21 |
CCDC87 | interactor | 5 | 0.700 | 1.833 | MAP65_ASE1 (PF03999, IPR007145): Microtubule associated protein (MAP65/ASE1 family) |
22 |
CCNH | oncoprotein | 9 | 0.694 | 3.349 | 5_3_exonuc_N (PF02739, IPR020046): 5'-3' exonuclease, N-terminal resolvase-like domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain Cyclin_C_2 (PF16899, IPR031658): Cyclin C-terminal domain |
23 |
CCNK | interactor | 7 | 0.762 | 1.769 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387) |
24 |
CCNT1 | oncoprotein | 34 | 0.189 | 329.699 | Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit MDFI (PF15316, IPR026134): MyoD family inhibitor |
25 |
CCNT2 | interactor | 12 | 0.348 | 22.111 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1 |
26 |
CCT3 | interactor | 14 | 0.516 | 19.397 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
27 |
CCT4 | interactor | 14 | 0.538 | 17.262 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
28 |
CCT5 | interactor | 12 | 0.606 | 11.370 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
29 |
CCT8 | interactor | 16 | 0.483 | 26.111 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
30 |
CDC34 | oncoprotein | 9 | 0.321 | 10.921 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
31 |
CDC37 | protein found in more fusions | 17 | 0.350 | 45.183 | CDC37_C (PF08564, IPR013873, SM01069): Cdc37 C terminal domain CDC37_M (PF08565, IPR013874, SM01070): Cdc37 Hsp90 binding domain CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding Rho_Binding (PF08912, IPR015008): Rho Binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding |
32 |
CDC5L | interactor | 47 | 0.212 | 435.739 | OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
33 |
CDC7 | interactor | 4 | 0.667 | 1.000 | Pkinase (PF00069, IPR000719): Protein kinase domain |
34 |
CDC73 | oncoprotein | 15 | 0.410 | 28.939 | CDC73_C (PF05179, IPR007852): RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N (PF16050, IPR032041): Paf1 complex subunit CDC73 N-terminal |
35 |
CDK12 | oncoprotein | 9 | 0.556 | 6.621 | Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp) Mem_trans (PF03547, IPR004776): Membrane transport protein Pkinase (PF00069, IPR000719): Protein kinase domain SOBP (PF15279, IPR026092): Sine oculis-binding protein CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106 |
36 |
CDK15 | interactor | 11 | 0.345 | 26.569 | Pkinase (PF00069, IPR000719): Protein kinase domain ACT_5 (PF13710): ACT domain |
37 |
CDK5R1 | oncoprotein | 2 | 1.000 | 0 | CDK5_activator (PF03261, IPR004944): Cyclin-dependent kinase 5 activator protein |
38 |
CDK7 | oncoprotein | 25 | 0.228 | 158.488 | Pkinase (PF00069, IPR000719): Protein kinase domain |
39 |
CENPA | interactor | 11 | 0.378 | 15.071 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
40 |
CKAP5 | interactor | 6 | 0.800 | 0.170 | HEAT (PF02985, IPR000357): HEAT repeat PAS_6 (PF08348, IPR013559): YheO-like PAS domain UME (PF08064, IPR012993, SM00802): UME (NUC010) domain CLASP_N (PF12348, IPR024395): CLASP N terminal Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region |
41 |
CLSPN | interactor | 4 | 0.667 | 2.000 | Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) NinG (PF05766, IPR008713): Bacteriophage Lambda NinG protein Presenilin (PF01080, IPR001108): Presenilin PTS_IIB (PF02302, IPR003501): PTS system, Lactose/Cellobiose specific IIB subunit XAP5 (PF04921, IPR007005): XAP5, circadian clock regulator Adaptin_binding (PF10199, IPR019341): Alpha and gamma adaptin binding protein p34 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal |
42 |
CNOT9 | protein found in more fusions | 6 | 0.700 | 0.576 | Rcd1 (PF04078, IPR007216): Cell differentiation family, Rcd1-like |
43 |
CSNK2B | interactor | 15 | 0.330 | 36.882 | CK_II_beta (PF01214, IPR000704, SM01085): Casein kinase II regulatory subunit |
44 |
CTDP1 | interactor | 8 | 0.571 | 6.219 | Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme FCP1_C (PF09309, IPR015388): FCP1, C-terminal NIF (PF03031, IPR004274): NLI interacting factor-like phosphatase SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain TFIIE-A_C (PF11521, IPR021600): C-terminal general transcription factor TFIIE alpha CAF1A (PF12253, IPR022043): Chromatin assembly factor 1 subunit A PTCB-BRCT (PF12738, IPR001357): twin BRCT domain HlyD_D23 (PF16576, IPR032317): Barrel-sandwich domain of CusB or HlyD membrane-fusion |
45 |
CTR9 | interactor | 14 | 0.418 | 30.675 | DUF702 (PF05142, IPR007818): Domain of unknown function (DUF702) Pap_E4 (PF02711, IPR003861): E4 protein SPT16 (PF08644, IPR013953): FACT complex subunit (SPT16/CDC68) TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat DUF2175 (PF09943, IPR018686): Uncharacterized protein conserved in archaea (DUF2175) TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_14 (PF13428): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
46 |
CUL1 | oncoprotein | 46 | 0.272 | 336.499 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
47 |
DDX5 | oncoprotein | 21 | 0.500 | 42.849 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
48 |
DTYMK | interactor | 3 | 0.667 | 0.083 | Thymidylate_kin (PF02223): Thymidylate kinase |
49 |
EAF1 | suppressor | 10 | 0.622 | 8.971 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Peroxin-3 (PF04882, IPR006966): Peroxin-3 EAF (PF09816, IPR019194): RNA polymerase II transcription elongation factor |
50 |
ELAVL1 | oncoprotein | 44 | 0.169 | 523.173 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
51 |
ELL | oncoprotein | 9 | 0.667 | 5.571 | Occludin_ELL (PF07303, IPR010844): Occludin homology domain ELL (PF10390, IPR019464): RNA polymerase II elongation factor ELL |
52 |
ELL2 | interactor | 11 | 0.636 | 11.890 | Occludin_ELL (PF07303, IPR010844): Occludin homology domain Wbp11 (PF09429, IPR019007): WW domain binding protein 11 ELL (PF10390, IPR019464): RNA polymerase II elongation factor ELL |
53 |
EXOSC5 | interactor | 2 | 1.000 | 0 | RNase_PH (PF01138, IPR001247): 3' exoribonuclease family, domain 1 RNase_PH_C (PF03725, IPR015847): 3' exoribonuclease family, domain 2 |
54 |
FBXO25 | suppressor | 16 | 0.317 | 42.261 | Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A |
55 |
FGFR1 | oncoprotein | 4 | 1.000 | 0 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
56 |
FGFR4 | oncoprotein | 3 | 1.000 | 0 | APH (PF01636, IPR002575): Phosphotransferase enzyme family I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ig_3 (PF13927): Immunoglobulin domain |
57 |
FGR | oncoprotein | 3 | 1.000 | 0 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
58 |
FKBP5 | interactor | 10 | 0.556 | 11.591 | FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat NuDC (PF16273, IPR032572): Nuclear distribution C domain |
59 |
GATA6 | interactor | 1 | 0 | 0 | GATA-N (PF05349, IPR008013): GATA-type transcription activator, N-terminal OrfB_Zn_ribbon (PF07282, IPR010095): Putative transposase DNA-binding domain DUF2387 (PF09526, IPR012658): Probable metal-binding protein (DUF2387) GATA (PF00320, IPR000679, SM00401): GATA zinc finger |
60 |
GRN | oncoprotein | 2 | 1.000 | 0 | Granulin (PF00396, IPR000118, SM00277): Granulin Lustrin_cystein (PF14625, IPR028150): Lustrin, cysteine-rich repeated domain |
61 |
GSS | protein found in more fusions | 3 | 1.000 | 0 | GSH_synth_ATP (PF03917, IPR005615): Eukaryotic glutathione synthase, ATP binding domain |
62 |
GTF2F1 | interactor | 14 | 0.407 | 26.885 | TFIIF_alpha (PF05793, IPR008851): Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) |
63 |
HEXIM1 | oncoprotein | 17 | 0.368 | 46.693 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 DivIC (PF04977, IPR007060): Septum formation initiator Shugoshin_N (PF07558, IPR011516): Shugoshin N-terminal coiled-coil region HEXIM (PF15313, IPR024872): Hexamethylene bis-acetamide-inducible protein |
64 |
HEXIM2 | interactor | 7 | 0.733 | 1.272 | bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper HEXIM (PF15313, IPR024872): Hexamethylene bis-acetamide-inducible protein GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor |
65 |
HINT1 | suppressor | 7 | 0.533 | 5.500 | HIT (PF01230, IPR001310): HIT domain |
66 |
HIST2H2BE | interactor | 15 | 0.257 | 56.919 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
67 |
HLTF | oncoprotein | 7 | 0.533 | 3.154 | HIRAN (PF08797, IPR014905, SM00910): HIRAN domain SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
68 |
HNRNPA0 | interactor | 15 | 0.810 | 3.439 | SAP130_C (PF16014, IPR031963): Histone deacetylase complex subunit SAP130 C-terminus |
69 |
HNRNPA1 | interactor | 38 | 0.336 | 203.591 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
70 |
HNRNPA2B1 | oncoprotein | 21 | 0.481 | 42.943 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
71 |
HNRNPD | oncoprotein | 23 | 0.489 | 44.051 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Keratin_2_head (PF16208, IPR032444): Keratin type II head |
72 |
HNRNPH1 | oncoprotein | 25 | 0.547 | 43.660 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
73 |
HNRNPK | oncoprotein | 25 | 0.511 | 46.676 | ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
74 |
HNRNPR | interactor | 22 | 0.537 | 44.127 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
75 |
HNRNPU | interactor | 35 | 0.383 | 145.914 | CDC45 (PF02724, IPR003874): CDC45-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
76 |
HSP90AA1 | oncoprotein | 41 | 0.232 | 377.171 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
77 |
HSP90AA4P | interactor | 3 | 0.667 | 0.222 | DUF11 (PF01345, IPR001434): Domain of unknown function DUF11 fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase (PF00069, IPR000719): Protein kinase domain PPAK (PF02818, IPR004168): PPAK motif Titin_Z (PF09042, IPR015129): Titin Z V-set (PF07686, IPR013106): Immunoglobulin V-set domain Y_Y_Y (PF07495, IPR011123): Y_Y_Y domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) Ig_3 (PF13927): Immunoglobulin domain |
78 |
HSP90AA5P | interactor | 5 | 0.900 | 0.222 | NA |
79 |
HSP90AB1 | oncoprotein | 27 | 0.332 | 110.922 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
80 |
HSP90AB3P | interactor | 5 | 0.700 | 1.122 | DUF11 (PF01345, IPR001434): Domain of unknown function DUF11 fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase (PF00069, IPR000719): Protein kinase domain PPAK (PF02818, IPR004168): PPAK motif Titin_Z (PF09042, IPR015129): Titin Z V-set (PF07686, IPR013106): Immunoglobulin V-set domain Y_Y_Y (PF07495, IPR011123): Y_Y_Y domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) Ig_3 (PF13927): Immunoglobulin domain |
81 |
HSP90AB4P | interactor | 3 | 0.667 | 0.222 | DUF11 (PF01345, IPR001434): Domain of unknown function DUF11 fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase (PF00069, IPR000719): Protein kinase domain PPAK (PF02818, IPR004168): PPAK motif Titin_Z (PF09042, IPR015129): Titin Z V-set (PF07686, IPR013106): Immunoglobulin V-set domain Y_Y_Y (PF07495, IPR011123): Y_Y_Y domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) Ig_3 (PF13927): Immunoglobulin domain |
82 |
HSPA1A | interactor | 18 | 0.490 | 28.047 | HSP70 (PF00012, IPR013126): Hsp70 protein |
83 |
HSPA2 | interactor | 9 | 0.556 | 4.342 | HSP70 (PF00012, IPR013126): Hsp70 protein |
84 |
HSPA5 | oncoprotein | 31 | 0.379 | 120.037 | HSP70 (PF00012, IPR013126): Hsp70 protein |
85 |
HSPA6 | interactor | 11 | 0.564 | 5.227 | HSP70 (PF00012, IPR013126): Hsp70 protein |
86 |
HSPD1 | oncoprotein | 18 | 0.458 | 34.374 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
87 |
IGF2BP1 | oncoprotein | 10 | 0.689 | 2.824 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_1 (PF00013, IPR004088, SM00322): KH domain KH_4 (PF13083): KH domain MOEP19 (PF16005, IPR031952): KH-like RNA-binding domain |
88 |
IGF2BP2 | interactor | 7 | 0.762 | 0.791 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_1 (PF00013, IPR004088, SM00322): KH domain KH_4 (PF13083): KH domain |
89 |
IL6ST | oncoprotein | 3 | 1.000 | 0 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain IL6Ra-bind (PF09240, IPR015321): Interleukin-6 receptor alpha chain, binding Lep_receptor_Ig (PF06328, IPR010457): Ig-like C2-type domain Pur_ac_phosph_N (PF16656, IPR015914): Purple acid Phosphatase, N-terminal domain |
90 |
ILF2 | interactor | 18 | 0.575 | 20.366 | DZF (PF07528, IPR006561, SM00572): DZF domain |
91 |
ILKAP | interactor | 1 | 0 | 0 | PP2C (PF00481, IPR001932): Protein phosphatase 2C |
92 |
IMMT | protein found in more fusions | 7 | 0.400 | 4.133 | Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein |
93 |
KLC4 | interactor | 2 | 1.000 | 0 | Flagellin_N (PF00669, IPR001029): Bacterial flagellin N-terminal helical region Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat LUD_dom (PF02589): LUD domain |
94 |
KMT2A | oncoprotein | 15 | 0.484 | 24.029 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 SET (PF00856, IPR001214, SM00317): SET domain zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain zf-HC5HC2H (PF13771): PHD-like zinc-binding domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) |
95 |
KPNA2 | interactor | 18 | 0.307 | 58.322 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat IBB (PF01749, IPR002652): Importin beta binding domain Arm_3 (PF16186, IPR032413): Atypical Arm repeat |
96 |
LANCL2 | interactor | 2 | 1.000 | 0 | Glyco_hydro_127 (PF07944, IPR012878): Beta-L-arabinofuranosidase, GH127 LANC_like (PF05147, IPR007822): Lanthionine synthetase C-like protein |
97 |
LARP7 | interactor | 13 | 0.449 | 23.037 | Agouti (PF05039, IPR007733, SM00792): Agouti protein DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) La (PF05383, IPR006630, SM00715): La domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 (PF08777, IPR014886): RNA binding motif |
98 |
MARS | oncoprotein | 7 | 0.429 | 6.998 | Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA DUF16 (PF01519, IPR002862): Protein of unknown function DUF16 GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain tRNA-synt_1g (PF09334, IPR015413): tRNA synthetases class I (M) WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain GST_N_2 (PF13409, IPR004045): Glutathione S-transferase, N-terminal domain |
99 |
MATR3 | interactor | 16 | 0.686 | 7.814 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM60A (PF15396, IPR026065): Protein Family FAM60A |
100 |
MBP | interactor | 3 | 0.667 | 0.500 | Myelin_MBP (PF01669, IPR000548): Myelin basic protein |
101 |
MDFIC | interactor | 3 | 1.000 | 0 | SNAP-25 (PF00835, IPR000928): SNAP-25 family MDFI (PF15316, IPR026134): MyoD family inhibitor |
102 |
MDM2 | oncoprotein | 22 | 0.295 | 67.609 | Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
103 |
MED1 | interactor | 15 | 0.440 | 30.273 | Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 Med1 (PF10744, IPR019680): Mediator of RNA polymerase II transcription subunit 1 DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR |
104 |
MED12 | oncoprotein | 6 | 0.800 | 1.452 | Med12 (PF09497, IPR019035): Transcription mediator complex subunit Med12 Peptidase_S15 (PF02129, IPR000383): X-Pro dipeptidyl-peptidase (S15 family) DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 DUF2877 (PF11392, IPR021530): Protein of unknown function (DUF2877) Med12-PQL (PF12144, IPR021989): Eukaryotic Mediator 12 catenin-binding domain Med12-LCEWAV (PF12145, IPR021990): Eukaryotic Mediator 12 subunit domain CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance |
105 |
MED26 | interactor | 18 | 0.399 | 64.098 | Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain Med26_C (PF15693, IPR031416): Mediator complex subunit 26 C-terminal Med26_M (PF15694, IPR031417): Mediator complex subunit 26 middle domain |
106 |
MED28 | interactor | 8 | 0.810 | 1.633 | cwf21 (PF08312, IPR013170, SM01115): cwf21 domain Med28 (PF11594, IPR021640): Mediator complex subunit 28 |
107 |
MEPCE | interactor | 50 | 0.155 | 671.481 | Bin3 (PF06859, IPR010675): Bicoid-interacting protein 3 (Bin3) Methyltransf_23 (PF13489): Methyltransferase domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 DLEU7 (PF15760, IPR031510): Leukemia-associated protein 7 |
108 |
MLLT1 | oncoprotein | 14 | 0.571 | 20.157 | DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) Peptidase_S64 (PF08192, IPR012985): Peptidase family S64 YEATS (PF03366, IPR005033): YEATS family DDRGK (PF09756, IPR019153, SM01128): DDRGK domain |
109 |
MLLT3 | oncoprotein | 13 | 0.590 | 19.014 | Peptidase_S64 (PF08192, IPR012985): Peptidase family S64 YEATS (PF03366, IPR005033): YEATS family DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446) Sox_N (PF12444, IPR022151): Sox developmental protein N terminal PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal NKAP (PF15692): NF-kappa-B-activating protein BET (PF17035, IPR027353): Bromodomain extra-terminal - transcription regulation |
110 |
MRPS27 | interactor | 7 | 0.762 | 1.330 | MRP-S27 (PF10037, IPR019266): Mitochondrial 28S ribosomal protein S27 |
111 |
MSH2 | oncoprotein | 17 | 0.375 | 32.983 | MutS_I (PF01624, IPR007695): MutS domain I MutS_II (PF05188, IPR007860): MutS domain II MutS_V (PF00488, IPR000432, SM00534): MutS domain V MutS_III (PF05192, IPR007696, SM00533): MutS domain III AAA_27 (PF13514): AAA domain |
112 |
MSL1 | interactor | 7 | 0.714 | 2.638 | Herpes_UL6 (PF01763, IPR002660): Herpesvirus UL6 like KLRAQ (PF10205, IPR019343): Predicted coiled-coil domain-containing protein PEHE (PF15275, IPR029332): PEHE domain MSL1_dimer (PF16801, IPR031840): Dimerisation domain of Male-specific-Lethal 1 |
113 |
MSL2 | interactor | 7 | 0.762 | 1.841 | MSL2-CXC (PF16682, IPR032049): CXC domain of E3 ubiquitin-protein ligase MSL2 zf-RING_10 (PF16685, IPR032043): zinc RING finger of MSL2 |
114 |
MYBL2 | oncoprotein | 4 | 0.667 | 0.400 | Cmyb_C (PF09316, IPR015395): C-myb, C-terminal Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
115 |
MYC | oncoprotein | 54 | 0.175 | 654.508 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
116 |
NUFIP1 | interactor | 5 | 0.600 | 1.200 | NUFIP1 (PF10453, IPR019496): Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DUF3395 (PF11875, IPR024586): Domain of unknown function (DUF3395) zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2HC_2 (PF13913): zinc-finger of a C2HC-type |
117 |
OXSR1 | interactor | 5 | 0.700 | 1.300 | Pkinase (PF00069, IPR000719): Protein kinase domain OSR1_C (PF12202, IPR024678): Oxidative-stress-responsive kinase 1 C terminal DUF4423 (PF14394, IPR025537): Domain of unknown function (DUF4423) |
118 |
P4HA1 | interactor | 4 | 0.667 | 0.404 | P4Ha_N (PF08336, IPR013547): Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat 2OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily |
119 |
PAF1 | oncoprotein | 15 | 0.381 | 46.488 | Paf1 (PF03985, IPR007133): Paf1 MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 |
120 |
PAXIP1 | interactor | 12 | 0.318 | 24.056 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase SURF6 (PF04935, IPR007019): Surfeit locus protein 6 DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance PTCB-BRCT (PF12738, IPR001357): twin BRCT domain BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT (PF16759, IPR031916): DNA ligase 3 BRCT domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
121 |
PCBP2 | protein found in more fusions | 18 | 0.382 | 38.764 | Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein KH_2 (PF07650, IPR004044): KH domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
122 |
PGC | interactor | 2 | 1.000 | 0 | A1_Propeptide (PF07966, IPR012848): A1 Propeptide Asp (PF00026, IPR001461): Eukaryotic aspartyl protease |
123 |
PLEC | oncoprotein | 6 | 0.800 | 0.869 | CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family FUSC (PF04632, IPR006726): Fusaric acid resistance protein family RNA_pol_Rbc25 (PF08292, IPR013238): RNA polymerase III subunit Rpc25 S10_plectin (PF03501, IPR005326): Plectin/S10 domain Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein DUF2229 (PF09989, IPR018709): CoA enzyme activase uncharacterised domain (DUF2229) Plectin (PF00681, IPR001101, SM00250): Plectin repeat YlqD (PF11068, IPR021297): YlqD protein Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391) DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140) |
124 |
PMS1 | oncoprotein | 11 | 0.356 | 13.638 | DNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain HTH_Tnp_IS630 (PF01710, IPR002622): Transposase HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box MRP-L46 (PF11788, IPR021757): 39S mitochondrial ribosomal protein L46 HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase |
125 |
POLR2A | protein found in more fusions | 32 | 0.245 | 225.040 | RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat |
126 |
RAD21 | oncoprotein | 19 | 0.327 | 52.009 | Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
127 |
RB1 | oncoprotein | 15 | 0.295 | 46.109 | RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452) DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592) |
128 |
RBM39 | oncoprotein | 9 | 0.667 | 3.731 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 RBM39linker (PF15519, IPR029123): linker between RRM2 and RRM3 domains in RBM39 protein |
129 |
RCHY1 | oncoprotein | 5 | 1.000 | 0 | C1_2 (PF03107, IPR004146): C1 domain zf-CHY (PF05495, IPR008913): CHY zinc finger zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 zinc_ribbon_6 (PF14599): Zinc-ribbon |
130 |
RELA | oncoprotein | 18 | 0.353 | 41.667 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
131 |
RFC4 | interactor | 14 | 0.418 | 21.919 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) Rad17 (PF03215): Rad17 cell cycle checkpoint protein Rep_fac_C (PF08542, IPR013748): Replication factor C C-terminal domain AAA_assoc_2 (PF16193, IPR032423): AAA C-terminal domain |
132 |
RMND5B | interactor | 1 | 0 | 0 | Sec15 (PF04091, IPR007225): Exocyst complex subunit Sec15-like CLTH (PF10607, IPR024964): CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger |
133 |
RN7SK | interactor | 10 | 0.600 | 8.092 | NA |
134 |
RNF20 | interactor | 16 | 0.324 | 48.533 | Allexi_40kDa (PF05549, IPR008398): Allexivirus 40kDa protein Atrophin-1 (PF03154, IPR002951): Atrophin-1 family BRE1 (PF08647, IPR013956): BRE1 E3 ubiquitin ligase DUF1690 (PF07956, IPR012471): Protein of Unknown function (DUF1690) HrpB7 (PF09486, IPR013392): Bacterial type III secretion protein (HrpB7) Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region Sox_N (PF12444, IPR022151): Sox developmental protein N terminal DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion |
135 |
RNF40 | protein found in more fusions | 17 | 0.325 | 50.561 | BRE1 (PF08647, IPR013956): BRE1 E3 ubiquitin ligase DUF745 (PF05335, IPR007999): Protein of unknown function (DUF745) ZapB (PF06005, IPR009252): Cell division protein ZapB EzrA (PF06160, IPR010379): Septation ring formation regulator, EzrA FlgN (PF05130, IPR007809): FlgN protein Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat SpoIIE (PF07228, IPR001932): Stage II sporulation protein E (SpoIIE) T5orf172 (PF10544, IPR018306, SM00974): T5orf172 domain XhlA (PF10779, IPR019715): Haemolysin XhlA ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) KASH_CCD (PF14662, IPR028168): Coiled-coil region of CCDC155 or KASH Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin zf-RING_6 (PF14835): zf-RING of BARD1-type protein |
136 |
RPN1 | oncoprotein | 12 | 0.470 | 14.448 | Ribophorin_I (PF04597, IPR007676): Ribophorin I CtIP_N (PF10482, IPR019518): Tumour-suppressor protein CtIP N-terminal domain |
137 |
RPS4X | interactor | 12 | 0.621 | 4.476 | KOW (PF00467, IPR005824, SM00739): KOW motif Ribosomal_S4e (PF00900, IPR013845): Ribosomal family S4e RS4NT (PF08071, IPR013843): RS4NT (NUC023) domain S4 (PF01479, IPR002942, SM00363): S4 domain 40S_S4_C (PF16121, IPR032277): 40S ribosomal protein S4 C-terminus |
138 |
RUVBL1 | oncoprotein | 19 | 0.301 | 57.056 | TIP49 (PF06068, IPR010339): TIP49 C-terminus |
139 |
RUVBL2 | oncoprotein | 29 | 0.280 | 146.454 | TIP49 (PF06068, IPR010339): TIP49 C-terminus |
140 |
SART3 | protein found in more fusions | 7 | 0.467 | 4.089 | CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) DUF1866 (PF08952, IPR015047, SM01165): Domain of unknown function (DUF1866) DUF1993 (PF09351, IPR018531): Domain of unknown function (DUF1993) Lsm_interact (PF05391, IPR008669): Lsm interaction motif Phage_GPD (PF05954): Phage late control gene D protein (GPD) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Suf (PF05843, IPR008847): Suppressor of forked protein (Suf) TPR_14 (PF13428): Tetratricopeptide repeat MRI (PF15325, IPR028278): Modulator of retrovirus infection LSM_int_assoc (PF16605): LSM-interacting associated unstructured |
141 |
SEC31A | interactor | 2 | 1.000 | 0 | P3A (PF08727, IPR014838): Poliovirus 3A protein like SRA1 (PF07304, IPR009917): Steroid receptor RNA activator (SRA1) Sec16_C (PF12931, IPR024298): Sec23-binding domain of Sec16 Sec16 (PF12932, IPR024340): Vesicle coat trafficking protein Sec16 mid-region |
142 |
SETD1B | interactor | 3 | 0.667 | 0.400 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET (PF00856, IPR001214, SM00317): SET domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein N-SET (PF11764, IPR024657): COMPASS (Complex proteins associated with Set1p) component N CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance 4HBT_3 (PF13622): Thioesterase-like superfamily SOBP (PF15279, IPR026092): Sine oculis-binding protein PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
143 |
SKIV2L | interactor | 1 | 0 | 0 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DSHCT (PF08148, IPR012961, SM01142): DSHCT (NUC185) domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DUF3516 (PF12029, IPR021904): Domain of unknown function (DUF3516) rRNA_proc-arch (PF13234, IPR025696): rRNA-processing arch domain |
144 |
SKP1 | oncoprotein | 11 | 0.582 | 7.465 | Skp1 (PF01466, IPR016072, SM00512): Skp1 family, dimerisation domain Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain |
145 |
SKP2 | oncoprotein | 15 | 0.352 | 39.464 | LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRR_2 (PF07723, IPR013101): Leucine Rich Repeat LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) F-box-like (PF12937, IPR001810): F-box-like LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat |
146 |
SMAD1 | interactor | 8 | 0.667 | 3.456 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
147 |
SMAD2 | oncoprotein | 11 | 0.556 | 11.100 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
148 |
SMAD3 | oncoprotein | 15 | 0.484 | 22.245 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
149 |
SMC2 | interactor | 10 | 0.511 | 12.703 | SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) DUF4201 (PF13870, IPR025254): Domain of unknown function (DUF4201) |
150 |
SMC4 | interactor | 8 | 0.750 | 1.914 | SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain Caskin-Pro-rich (PF16907): Proline rich region of Caskin proteins |
151 |
SNRPD2P1 | interactor | 2 | 1.000 | 0 | NA |
152 |
SNW1 | protein found in more fusions | 52 | 0.224 | 520.662 | SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain |
153 |
SQSTM1 | oncoprotein | 11 | 0.444 | 15.913 | PB1 (PF00564, IPR000270, SM00666): PB1 domain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type UBA_5 (PF16577, IPR015940): UBA domain |
154 |
SRCAP | interactor | 4 | 0.833 | 0.333 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif HSA (PF07529, IPR014012, SM00573): HSA RXT2_N (PF08595, IPR013904): RXT2-like, N-terminal SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DBINO (PF13892, IPR020838): DNA-binding domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal |
155 |
STAT3 | oncoprotein | 16 | 0.210 | 57.955 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain |
156 |
STIP1 | interactor | 12 | 0.394 | 24.283 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat Wtap (PF17098, IPR029732): Pre-mRNA-splicing regulator WTAP |
157 |
SUPT16H | interactor | 14 | 0.256 | 37.883 | Nop14 (PF04147, IPR007276): Nop14-like family Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24 Rtt106 (PF08512, IPR013719): Histone chaperone Rttp106-like SPT16 (PF08644, IPR013953): FACT complex subunit (SPT16/CDC68) Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal FACT-Spt16_Nlob (PF14826, IPR029148): FACT complex subunit SPT16 N-terminal lobe domain |
158 |
SUPT5H | interactor | 17 | 0.324 | 45.818 | KOW (PF00467, IPR005824, SM00739): KOW motif Ribonuc_P_40 (PF08584, IPR013893): Ribonuclease P 40kDa (Rpp40) subunit Spt5-NGN (PF03439, IPR005100): Early transcription elongation factor of RNA pol II, NGN section Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF3912 (PF13051, IPR025023): Protein of unknown function (DUF3912) |
159 |
SYNCRIP | interactor | 20 | 0.521 | 42.846 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
160 |
TAF7 | interactor | 4 | 0.667 | 0.900 | DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) ELM2 (PF01448, IPR000949): ELM2 domain TAFII55_N (PF04658, IPR006751): TAFII55 protein conserved region XhlA (PF10779, IPR019715): Haemolysin XhlA Noelin-1 (PF12308, IPR022082): Neurogenesis glycoprotein |
161 |
TAL1 | oncoprotein | 6 | 0.600 | 2.833 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG |
162 |
TCEA1 | oncoprotein | 11 | 0.455 | 17.605 | Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain TFIIS_C (PF01096, IPR001222): Transcription factor S-II (TFIIS) TFIIS_M (PF07500, IPR003618): Transcription factor S-II (TFIIS), central domain |
163 |
TERF1 | interactor | 21 | 0.289 | 77.937 | TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
164 |
TERF2 | interactor | 18 | 0.309 | 57.469 | Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain TERF2_RBM (PF16772, IPR031902): Telomeric repeat-binding factor 2 Rap1-binding motif |
165 |
TP53 | oncoprotein | 58 | 0.166 | 804.443 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
166 |
TRAF2 | interactor | 6 | 0.500 | 3.417 | MATH (PF00917, IPR002083, SM00061): MATH domain Sina (PF03145, IPR018121): Seven in absentia protein family SlyX (PF04102, IPR007236): SlyX zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger) |
167 |
TRAP1 | oncoprotein | 7 | 0.524 | 4.173 | HSP90 (PF00183, IPR001404): Hsp90 protein HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase |
168 |
TRIM28 | protein found in more fusions | 16 | 0.381 | 32.481 | ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2 |
169 |
TRIM33 | oncoprotein | 8 | 0.476 | 6.500 | PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Siva (PF05458, IPR022773): Cd27 binding protein (Siva) Spectrin (PF00435, IPR002017): Spectrin repeat TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Bromodomain (PF00439, IPR001487, SM00297): Bromodomain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger |
170 |
TRIP12 | interactor | 4 | 0.667 | 0.187 | Alpha_GJ (PF03229, IPR004913): Alphavirus glycoprotein J Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup WWE (PF02825, IPR004170, SM00678): WWE domain SOG2 (PF10428, IPR019487): RAM signalling pathway protein HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central HEAT_2 (PF13646): HEAT repeats |
171 |
TUBB4B | interactor | 13 | 0.474 | 13.300 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
172 |
UBE2A | interactor | 10 | 0.417 | 12.930 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
173 |
UBE2S | interactor | 6 | 0.500 | 2.137 | ALF (PF03752, IPR005506): Short repeats of unknown function UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
174 |
UBL4A | interactor | 25 | 0.350 | 85.367 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
175 |
UBR5 | protein found in more fusions | 10 | 0.361 | 14.444 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain SDA1 (PF05285, IPR007949): SDA1 HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain E3_UbLigase_EDD (PF11547, IPR024725): E3 ubiquitin ligase EDD PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein |
176 |
XRCC3 | oncoprotein | 10 | 0.333 | 18.818 | Rad51 (PF08423, IPR013632): Rad51 RNA_pol_A_CTD (PF03118, IPR011260): Bacterial RNA polymerase, alpha chain C terminal domain |
177 |
YBX1 | oncoprotein | 19 | 0.468 | 34.348 | CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2 |
178 |
ZC3H13 | interactor | 8 | 0.571 | 8.400 | FGF-BP1 (PF06473, IPR010510): FGF binding protein 1 (FGF-BP1) zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) PET117 (PF15786, IPR031568): PET assembly of cytochrome c oxidase, mitochondrial |