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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins CDC42EP3 (from a repository: Fri Nov 25 14:20:56 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)8
The number (and %) of the onco-proteins2 (25.00 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)11 (39.29 %)
The number (and %) of affected PPIs8 (72.73 %)
The number of possible different fusions2
PPI diameter2
PPI radius1
The average degree of PPI2.000
Assortativity coefficient-0.4880
The network average Clustering coefficient0.256
The number (and %) of a zero Clustering coefficients5 (62.50 %)
The number (and %) of a zero Betweenness Centrality7 (87.50 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: CDC42EP3 All fusions
: CN294726; BU177566;
Proteins found in more fusions CDC42EP3 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 CDC42EP3parental protein80.04840.000PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
BORG_CEP (PF14957, IPR029273): Cdc42 effector
2 CDC42oncoprotein200Ras (PF00071, IPR001806, SM00173): Ras family
3 RHOQinteractor100Ras (PF00071, IPR001806, SM00173): Ras family
4 SEPT6oncoprotein21.0000Septin (PF00735, IPR000038): Septin
DUF2959 (PF11172, IPR021342): Protein of unknown function (DUF2959)
5 SEPT7interactor21.0000Fez1 (PF06818): Fez1
Septin (PF00735, IPR000038): Septin
6 SNCAinteractor200Synuclein (PF01387, IPR001058): Synuclein
7 SRPK1interactor100FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
Pkinase (PF00069, IPR000719): Protein kinase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
8 UMPSinteractor100OMPdecase (PF00215, IPR001754, SM00934): Orotidine 5'-phosphate decarboxylase / HUMPS family
Pribosyltran (PF00156, IPR000836): Phosphoribosyl transferase domain

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