1 |
CDC37 | parental protein | 212 | 0.056 | 28243.209 | CDC37_C (PF08564, IPR013873, SM01069): Cdc37 C terminal domain CDC37_M (PF08565, IPR013874, SM01070): Cdc37 Hsp90 binding domain CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding Rho_Binding (PF08912, IPR015008): Rho Binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding |
2 |
A2M | protein found in more fusions | 26 | 0.277 | 129.292 | A2M (PF00207, IPR001599): Alpha-2-macroglobulin family A2M_comp (PF07678, IPR011626): A-macroglobulin complement component A2M_N (PF01835, IPR002890): MG2 domain A2M_N_2 (PF07703, IPR011625): Alpha-2-macroglobulin family N-terminal region A2M_recep (PF07677, IPR009048): A-macroglobulin receptor MP (PF01107, IPR028919): Viral movement protein (MP) SVA (PF05326, IPR007990): Seminal vesicle autoantigen (SVA) Thiol-ester_cl (PF10569, IPR019565): Alpha-macro-globulin thiol-ester bond-forming region |
3 |
ABL2 | oncoprotein | 6 | 0.800 | 0.567 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding SH3_1 (PF00018, IPR001452, SM00326): SH3 domain NHS (PF15273, IPR024845): NHS-like |
4 |
AHCYL1 | suppressor | 9 | 0.500 | 8.677 | AdoHcyase (PF05221, IPR000043, SM00996): S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD (PF00670, IPR015878, SM00997): S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF515 (PF04415, IPR007509): Protein of unknown function (DUF515) Big_3_5 (PF16640, IPR032109): Bacterial Ig-like domain (group 3) |
5 |
AHSA1 | interactor | 26 | 0.366 | 97.749 | Aha1_N (PF09229, IPR015310, SM01000): Activator of Hsp90 ATPase, N-terminal AHSA1 (PF08327, IPR013538): Activator of Hsp90 ATPase homolog 1-like protein |
6 |
AIP | suppressor | 10 | 0.422 | 13.511 | FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat |
7 |
AKT1 | oncoprotein | 35 | 0.299 | 191.200 | PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
8 |
APOE | protein found in more fusions | 15 | 0.582 | 15.040 | Apolipoprotein (PF01442, IPR000074): Apolipoprotein A1/A4/E domain TipAS (PF07739, IPR012925): TipAS antibiotic-recognition domain |
9 |
APP | protein found in more fusions | 55 | 0.131 | 878.311 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
10 |
AR | oncoprotein | 22 | 0.314 | 60.681 | Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
11 |
ARAF | oncoprotein | 12 | 0.424 | 14.687 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
12 |
ATG101 | interactor | 4 | 0.500 | 2.067 | ATG101 (PF07855, IPR012445): Autophagy-related protein 101 |
13 |
AURKA | oncoprotein | 23 | 0.346 | 66.605 | Pkinase (PF00069, IPR000719): Protein kinase domain MTBP_C (PF14920, IPR029418): MDM2-binding |
14 |
AURKB | interactor | 19 | 0.327 | 55.390 | Pkinase (PF00069, IPR000719): Protein kinase domain |
15 |
AURKC | interactor | 6 | 0.800 | 1.182 | Pkinase (PF00069, IPR000719): Protein kinase domain |
16 |
BRAF | oncoprotein | 14 | 0.628 | 7.090 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
17 |
BTBD10 | interactor | 1 | 0 | 0 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) BTB_3 (PF16017): BTB/POZ domain |
18 |
C19orf44 | interactor | 1 | 0 | 0 | DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) |
19 |
CC2D1A | interactor | 5 | 0.600 | 2.067 | C2 (PF00168, IPR000008, SM00239): C2 domain FUSC (PF04632, IPR006726): Fusaric acid resistance protein family Snf7 (PF03357, IPR005024): Snf7 DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391) LELP1 (PF15042, IPR026076): Late cornified envelope-like proline-rich protein 1 |
20 |
CDC25C | oncoprotein | 6 | 0.667 | 0.971 | M-inducer_phosp (PF06617, IPR000751): M-phase inducer phosphatase Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain |
21 |
CDC37L1 | interactor | 13 | 0.526 | 16.309 | CDC37_M (PF08565, IPR013874, SM01070): Cdc37 Hsp90 binding domain |
22 |
CDCA5 | interactor | 6 | 0.400 | 1.934 | Sororin (PF09666, IPR018605): Sororin protein |
23 |
CDK1 | oncoprotein | 19 | 0.255 | 70.849 | Pkinase (PF00069, IPR000719): Protein kinase domain |
24 |
CDK11A | oncoprotein | 5 | 0.600 | 2.122 | DDHD (PF02862, IPR004177, SM01127): DDHD domain eIF_4EBP (PF05456, IPR008606): Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Pkinase (PF00069, IPR000719): Protein kinase domain RIO1 (PF01163, IPR018934): RIO1 family DUF4355 (PF14265, IPR025580): Domain of unknown function (DUF4355) DHHW (PF14286, IPR025945): DHHW protein DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748) |
25 |
CDK11B | oncoprotein | 8 | 0.714 | 3.338 | DDHD (PF02862, IPR004177, SM01127): DDHD domain DivIC (PF04977, IPR007060): Septum formation initiator Pkinase (PF00069, IPR000719): Protein kinase domain DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748) |
26 |
CDK13 | interactor | 13 | 0.474 | 17.790 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain Pkinase (PF00069, IPR000719): Protein kinase domain Macoilin (PF09726, IPR019130): Transmembrane protein THRAP3_BCLAF1 (PF15440, IPR029199): THRAP3/BCLAF1 family |
27 |
CDK15 | interactor | 6 | 0.933 | 0.400 | Pkinase (PF00069, IPR000719): Protein kinase domain ACT_5 (PF13710): ACT domain |
28 |
CDK18 | oncoprotein | 11 | 0.545 | 8.137 | APH (PF01636, IPR002575): Phosphotransferase enzyme family Pkinase (PF00069, IPR000719): Protein kinase domain |
29 |
CDK4 | oncoprotein | 14 | 0.505 | 18.428 | Pkinase (PF00069, IPR000719): Protein kinase domain |
30 |
CDK5 | oncoprotein | 11 | 0.622 | 8.589 | Pkinase (PF00069, IPR000719): Protein kinase domain |
31 |
CDK6 | suppressor | 9 | 0.500 | 8.200 | Pkinase (PF00069, IPR000719): Protein kinase domain |
32 |
CDK7 | oncoprotein | 13 | 0.424 | 19.293 | Pkinase (PF00069, IPR000719): Protein kinase domain |
33 |
CDK9 | protein found in more fusions | 17 | 0.350 | 37.706 | Pkinase (PF00069, IPR000719): Protein kinase domain |
34 |
CDKL1 | interactor | 2 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain |
35 |
CDKL2 | interactor | 3 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain |
36 |
CEP104 | interactor | 6 | 0.467 | 4.400 | ATP-synt_E_2 (PF08112, IPR012508): ATP synthase epsilon subunit zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding HEAT (PF02985, IPR000357): HEAT repeat PRP1_N (PF06424, IPR010491): PRP1 splicing factor, N-terminal UVR (PF02151, IPR001943): UvrB/uvrC motif zf-BED (PF02892, IPR003656, SM00614): BED zinc finger CLASP_N (PF12348, IPR024395): CLASP N terminal DZR (PF12773, IPR025874): Double zinc ribbon zf-C2H2_4 (PF13894): C2H2-type zinc finger |
37 |
CHGA | oncoprotein | 2 | 1.000 | 0 | Granin (PF01271, IPR001990): Granin (chromogranin or secretogranin) PP1_bind (PF15276, IPR029334): Protein phosphatase 1 binding |
38 |
CHORDC1 | interactor | 13 | 0.576 | 13.524 | CHORD (PF04968, IPR007051): CHORD CS (PF04969, IPR007052): CS domain |
39 |
CHUK | suppressor | 21 | 0.416 | 44.899 | Pkinase (PF00069, IPR000719): Protein kinase domain IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain |
40 |
CKS1B | oncoprotein | 5 | 0.833 | 0.400 | CKS (PF01111, IPR000789, SM01084): Cyclin-dependent kinase regulatory subunit |
41 |
CKS2 | oncoprotein | 5 | 0.833 | 0.333 | CKS (PF01111, IPR000789, SM01084): Cyclin-dependent kinase regulatory subunit |
42 |
CLK3 | interactor | 11 | 0.467 | 10.601 | Pkinase (PF00069, IPR000719): Protein kinase domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein |
43 |
CRYM | interactor | 2 | 1.000 | 0 | OCD_Mu_crystall (PF02423, IPR003462): Ornithine cyclodeaminase/mu-crystallin family |
44 |
CTTN | oncoprotein | 8 | 0.667 | 3.321 | FadA (PF09403, IPR018543): Adhesion protein FadA HS1_rep (PF02218, IPR003134): Repeat in HS1/Cortactin SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
45 |
CYP2C9 | interactor | 3 | 1.000 | 0 | p450 (PF00067, IPR001128): Cytochrome P450 |
46 |
DCTN1 | interactor | 11 | 0.289 | 18.847 | Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain FlgN (PF05130, IPR007809): FlgN protein HOOK (PF05622, IPR008636): HOOK protein SlyX (PF04102, IPR007236): SlyX TSC22 (PF01166, IPR000580): TSC-22/dip/bun family DUF2443 (PF10398, IPR019469): Protein of unknown function (DUF2443) ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding Dynactin (PF12455, IPR022157): Dynein associated protein Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease KELK (PF15796, IPR031597): KELK-motif containing domain of MRCK Ser/Thr protein kinase |
47 |
DDR1 | oncoprotein | 4 | 0.667 | 0.216 | Lamprin (PF06403, IPR009437): Lamprin Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase F5_F8_type_C (PF00754, IPR000421, SM00231): F5/8 type C domain DUF4381 (PF14316, IPR025489): Domain of unknown function (DUF4381) |
48 |
DDX17 | protein found in more fusions | 10 | 0.556 | 2.809 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Ferritin (PF00210, IPR008331): Ferritin-like domain GRP (PF07172, IPR010800): Glycine rich protein family Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
49 |
DDX5 | oncoprotein | 18 | 0.272 | 48.005 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
50 |
DEAF1 | interactor | 1 | 0 | 0 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SAND (PF01342, IPR000770, SM00258): SAND domain zf-MYND (PF01753, IPR002893): MYND finger |
51 |
DMWD | interactor | 3 | 0.667 | 1.000 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
52 |
DNAJB1 | suppressor | 15 | 0.486 | 21.121 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain |
53 |
DNAJC7 | interactor | 15 | 0.514 | 23.692 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat Rapsyn_N (PF10579, IPR019568): Rapsyn N-terminal myristoylation and linker region ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_17 (PF13431): Tetratricopeptide repeat |
54 |
ECSIT | interactor | 23 | 0.338 | 88.088 | ECSIT (PF06239, IPR010418): Evolutionarily conserved signalling intermediate in Toll pathway ECSIT_C (PF14784, IPR029342): C-terminal domain of the ECSIT protein |
55 |
EEF1A1 | suppressor | 31 | 0.347 | 118.415 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
56 |
EEF1A1P5 | interactor | 3 | 0.667 | 0.200 | NA |
57 |
EEF1A2 | oncoprotein | 8 | 0.321 | 6.529 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
58 |
EGFR | oncoprotein | 47 | 0.229 | 433.843 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
59 |
EIF2AK1 | interactor | 3 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain SlyX (PF04102, IPR007236): SlyX PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase |
60 |
EIF2AK2 | oncoprotein | 12 | 0.455 | 14.246 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Pkinase (PF00069, IPR000719): Protein kinase domain |
61 |
EIF3B | interactor | 7 | 0.429 | 3.705 | eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PGBA_C (PF15437, IPR032737): Plasminogen-binding protein pgbA C-terminal PALB2_WD40 (PF16756, IPR031920): Partner and localizer of BRCA2 WD40 domain Methyltr_RsmF_N (PF17125, IPR031341): N-terminal domain of 16S rRNA methyltransferase RsmF |
62 |
ELAVL3 | interactor | 7 | 0.571 | 4.067 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
63 |
EMD | interactor | 20 | 0.322 | 62.493 | LEM (PF03020, IPR003887, SM00540): LEM domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein |
64 |
ERBB2 | oncoprotein | 12 | 0.545 | 11.786 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
65 |
ERBB3 | oncoprotein | 22 | 0.295 | 86.199 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
66 |
ESRRB | suppressor | 22 | 0.290 | 90.918 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
67 |
EVC2 | interactor | 6 | 0.400 | 5.356 | HBS1_N (PF08938, IPR015033): HBS1 N-terminus DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342) Histone_HNS (PF00816, IPR001801): H-NS histone family EVC2_like (PF12297, IPR022076): Ellis van Creveld protein 2 like protein |
68 |
EWSR1 | oncoprotein | 26 | 0.257 | 119.731 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
69 |
EXOSC1 | interactor | 7 | 0.714 | 4.152 | EXOSC1 (PF10447, IPR019495): Exosome component EXOSC1/CSL4 ECR1_N (PF14382, IPR025721): Exosome complex exonuclease RRP4 N-terminal region |
70 |
FBXL12 | interactor | 8 | 0.607 | 6.043 | F-box-like (PF12937, IPR001810): F-box-like |
71 |
FBXO6 | interactor | 34 | 0.266 | 212.393 | FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like |
72 |
FBXW4 | oncoprotein | 7 | 0.429 | 8.186 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat F-box-like (PF12937, IPR001810): F-box-like F-box_4 (PF15966, IPR001810): F-box |
73 |
FER | protein found in more fusions | 8 | 0.714 | 2.817 | DivIC (PF04977, IPR007060): Septum formation initiator FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain Glyco_transf_28 (PF03033, IPR004276): Glycosyltransferase family 28 N-terminal domain PEP-utilisers_N (PF05524, IPR008731): PEP-utilising enzyme, N-terminal Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain Med29 (PF11568, IPR021018): Mediator complex subunit 29 |
74 |
FGFR3 | oncoprotein | 6 | 0.700 | 0.786 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ig_3 (PF13927): Immunoglobulin domain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
75 |
FKBP4 | interactor | 20 | 0.279 | 83.106 | FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat |
76 |
FKBP5 | interactor | 40 | 0.179 | 405.760 | FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat NuDC (PF16273, IPR032572): Nuclear distribution C domain |
77 |
FKBP6 | interactor | 6 | 0.667 | 2.134 | FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat |
78 |
FKBPL | interactor | 8 | 0.500 | 5.931 | BTAD (PF03704, IPR005158, SM01043): Bacterial transcriptional activator domain TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat |
79 |
FTSJ1 | interactor | 4 | 0.500 | 2.500 | FtsJ (PF01728, IPR002877): FtsJ-like methyltransferase |
80 |
GCDH | interactor | 9 | 0.639 | 8.421 | Acyl-CoA_dh_1 (PF00441, IPR009075): Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M (PF02770, IPR006091): Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N (PF02771, IPR013786): Acyl-CoA dehydrogenase, N-terminal domain |
81 |
GCH1 | interactor | 4 | 1.000 | 0 | GTP_cyclohydroI (PF01227, IPR020602): GTP cyclohydrolase I |
82 |
GFAP | protein found in more fusions | 12 | 0.400 | 14.760 | Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region |
83 |
GLMN | oncoprotein | 7 | 0.429 | 7.900 | Kinetochor_Ybp2 (PF08568, IPR013877): Uncharacterised protein family, YAP/Alf4/glomulin |
84 |
GRK5 | protein found in more fusions | 10 | 0.500 | 5.546 | Pkinase (PF00069, IPR000719): Protein kinase domain RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain |
85 |
HNRNPM | interactor | 12 | 0.515 | 11.272 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region |
86 |
HSP90AA1 | oncoprotein | 110 | 0.110 | 3634.113 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
87 |
HSP90AB1 | oncoprotein | 66 | 0.185 | 831.923 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
88 |
HSPA1A | interactor | 30 | 0.414 | 78.470 | HSP70 (PF00012, IPR013126): Hsp70 protein |
89 |
HSPA5 | oncoprotein | 33 | 0.369 | 120.966 | HSP70 (PF00012, IPR013126): Hsp70 protein |
90 |
HSPA8 | oncoprotein | 38 | 0.336 | 206.920 | HSP70 (PF00012, IPR013126): Hsp70 protein |
91 |
IFIT3 | interactor | 14 | 0.474 | 27.879 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
92 |
IFIT5 | interactor | 10 | 0.733 | 4.440 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat Sec16_C (PF12931, IPR024298): Sec23-binding domain of Sec16 TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_15 (PF13429): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
93 |
IKBKB | protein found in more fusions | 19 | 0.444 | 32.017 | FliT (PF05400, IPR008622): Flagellar protein FliT Glyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain Pkinase (PF00069, IPR000719): Protein kinase domain SlyX (PF04102, IPR007236): SlyX ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain |
94 |
IKBKE | interactor | 10 | 0.611 | 6.726 | IncA (PF04156, IPR007285): IncA protein Pkinase (PF00069, IPR000719): Protein kinase domain SlyX (PF04102, IPR007236): SlyX zf-RING_9 (PF13901, IPR025258): Putative zinc-RING and/or ribbon |
95 |
IKBKG | interactor | 29 | 0.291 | 124.984 | CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725) NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator |
96 |
IMMT | protein found in more fusions | 11 | 0.333 | 12.929 | Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein |
97 |
IRAK1 | interactor | 19 | 0.353 | 56.180 | Death (PF00531, IPR000488, SM00005): Death domain Pkinase (PF00069, IPR000719): Protein kinase domain |
98 |
IRAK2 | oncoprotein | 5 | 0.600 | 2.733 | Death (PF00531, IPR000488, SM00005): Death domain Pkinase (PF00069, IPR000719): Protein kinase domain |
99 |
LONP1 | interactor | 13 | 0.436 | 31.633 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) AAA_PrkA (PF08298, IPR013153, SM00763): PrkA AAA domain LON_substr_bdg (PF02190, IPR003111, SM00464): ATP-dependent protease La (LON) substrate-binding domain Lon_C (PF05362, IPR008269): Lon protease (S16) C-terminal proteolytic domain RuvB_N (PF05496, IPR008824): Holliday junction DNA helicase ruvB N-terminus AAA_23 (PF13476): AAA domain |
100 |
LOXL4 | oncoprotein | 6 | 0.867 | 0.536 | Lysyl_oxidase (PF01186, IPR001695): Lysyl oxidase SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain |
101 |
LRRK1 | interactor | 4 | 0.667 | 0.400 | Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase Pkinase (PF00069, IPR000719): Protein kinase domain TniB (PF05621, IPR008868): Bacterial TniB protein Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat COR (PF16095, IPR032171): C-terminal of Roc, COR, domain |
102 |
LRRK2 | oncoprotein | 14 | 0.551 | 16.467 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain DUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043) T2SSE (PF00437, IPR001482): Type II/IV secretion system protein Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase Pkinase (PF00069, IPR000719): Protein kinase domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) PQQ_2 (PF13360, IPR002372): PQQ-like domain LRR_8 (PF13855, IPR001611): Leucine rich repeat COR (PF16095, IPR032171): C-terminal of Roc, COR, domain |
103 |
LUC7L2 | protein found in more fusions | 12 | 0.364 | 14.594 | LUC7 (PF03194, IPR004882): LUC7 N_terminus Paramyxo_ncap (PF00973, IPR002021): Paramyxovirus nucleocapsid protein Methyltransf_32 (PF13679, IPR025714): Methyltransferase domain |
104 |
MAP3K1 | oncoprotein | 12 | 0.382 | 18.927 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Pkinase (PF00069, IPR000719): Protein kinase domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain Phostensin_N (PF13916, IPR025903): PP1-regulatory protein, Phostensin N-terminal |
105 |
MAP3K11 | interactor | 9 | 0.821 | 1.007 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH3_9 (PF14604, IPR001452): Variant SH3 domain |
106 |
MAP3K3 | oncoprotein | 10 | 0.556 | 3.914 | PB1 (PF00564, IPR000270, SM00666): PB1 domain Pkinase (PF00069, IPR000719): Protein kinase domain |
107 |
MAP3K7 | oncoprotein | 15 | 0.418 | 24.610 | Mnd1 (PF03962, IPR005647): Mnd1 family Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
108 |
MAPK7 | oncoprotein | 12 | 0.636 | 4.372 | Pkinase (PF00069, IPR000719): Protein kinase domain Rrn6 (PF10214, IPR019350): RNA polymerase I-specific transcription-initiation factor |
109 |
MASP1 | interactor | 4 | 0.500 | 1.733 | CUB (PF00431, IPR000859, SM00042): CUB domain Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat) Trypsin (PF00089, IPR001254, SM00020): Trypsin FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site |
110 |
MGEA5 | oncoprotein | 8 | 0.464 | 8.439 | NAGidase (PF07555, IPR011496): beta-N-acetylglucosaminidase |
111 |
MOV10 | interactor | 30 | 0.175 | 207.051 | AAA_12 (PF13087): AAA domain AAA_30 (PF13604): AAA domain |
112 |
MTOR | oncoprotein | 18 | 0.294 | 45.141 | DUF1104 (PF06518, IPR009488): Protein of unknown function (DUF1104) EPSP_synthase (PF00275, IPR001986): EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats TPR_19 (PF14559): Tetratricopeptide repeat |
113 |
MYLK4 | interactor | 3 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain |
114 |
MZT2B | interactor | 1 | 0 | 0 | MOZART2 (PF12926, IPR024332): Mitotic-spindle organizing gamma-tubulin ring associated |
115 |
NCOA5 | suppressor | 5 | 0.500 | 0.535 | Macoilin (PF09726, IPR019130): Transmembrane protein |
116 |
NEK6 | interactor | 3 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain |
117 |
NEK8 | interactor | 7 | 0.524 | 3.745 | Pkinase (PF00069, IPR000719): Protein kinase domain RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat |
118 |
NOS3 | interactor | 13 | 0.470 | 17.921 | FAD_binding_1 (PF00667, IPR003097): FAD binding domain Flavodoxin_1 (PF00258, IPR008254): Flavodoxin NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain HTH_15 (PF12324, IPR024259): Helix-turn-helix domain of alkylmercury lyase |
119 |
NPM1 | suppressor | 34 | 0.316 | 175.486 | Nucleoplasmin (PF03066): Nucleoplasmin SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain |
120 |
NTRK1 | oncoprotein | 74 | 0.136 | 1486.567 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
121 |
NUP98 | suppressor | 7 | 0.524 | 4.933 | Nucleoporin2 (PF04096, IPR007230): Nucleoporin autopeptidase Nup96 (PF12110, IPR021967): Nuclear protein 96 ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region Keratin_2_head (PF16208, IPR032444): Keratin type II head |
122 |
NXF1 | interactor | 34 | 0.170 | 270.751 | NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat |
123 |
OFD1 | protein found in more fusions | 16 | 0.267 | 49.914 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit GrpE (PF01025, IPR000740): GrpE NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein XhlA (PF10779, IPR019715): Haemolysin XhlA DUF3372 (PF11852, IPR024561): Domain of unknown function (DUF3372) LisH_2 (PF16045, IPR006594): LisH |
124 |
OGFR | interactor | 6 | 0.667 | 1.653 | OGFr_III (PF04680, IPR006770): Opioid growth factor receptor repeat OGFr_N (PF04664, IPR006757): Opioid growth factor receptor (OGFr) conserved region SspP (PF08179, IPR012614): Small acid-soluble spore protein P family MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c |
125 |
PANX1 | interactor | 1 | 0 | 0 | Innexin (PF00876, IPR000990): Innexin Pannexin_like (PF12534, IPR021040): Pannexin-like TM region of LRRC8 |
126 |
PATL1 | interactor | 4 | 0.833 | 0.087 | PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1 |
127 |
PCBP1 | oncoprotein | 15 | 0.562 | 13.614 | Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein KH_2 (PF07650, IPR004044): KH domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
128 |
PDZK1 | interactor | 5 | 0.800 | 0.733 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DUF4265 (PF14085, IPR025361): Domain of unknown function (DUF4265) |
129 |
PINK1 | protein found in more fusions | 10 | 0.611 | 4.319 | Pkinase (PF00069, IPR000719): Protein kinase domain |
130 |
PKM | oncoprotein | 23 | 0.423 | 56.737 | PK (PF00224, IPR015793): Pyruvate kinase, barrel domain PK_C (PF02887, IPR015795): Pyruvate kinase, alpha/beta domain |
131 |
POC1B | interactor | 2 | 1.000 | 0 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
132 |
PPHLN1 | interactor | 6 | 0.467 | 3.324 | Lge1 (PF11488): Transcriptional regulatory protein LGE1 HERV-K_REC (PF15695): Rec (regulator of expression encoded by corf) of HERV-K-113 |
133 |
PPID | interactor | 13 | 0.667 | 5.168 | Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat |
134 |
PPP5C | interactor | 15 | 0.457 | 18.070 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase PPP5 (PF08321, IPR013235): PPP5 TPR repeat region TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat |
135 |
PPP6R3 | interactor | 9 | 0.528 | 6.621 | SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein |
136 |
PRAM1 | interactor | 7 | 0.667 | 5.376 | hSH3 (PF14603, IPR029294): Helically-extended SH3 domain |
137 |
PRDX2 | interactor | 13 | 0.487 | 25.848 | AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin |
138 |
PRKAA1 | suppressor | 13 | 0.474 | 19.260 | Pkinase (PF00069, IPR000719): Protein kinase domain AdenylateSensor (PF16579, IPR032270): Adenylate sensor of SNF1-like protein kinase |
139 |
PRKCI | interactor | 11 | 0.455 | 11.011 | PB1 (PF00564, IPR000270, SM00666): PB1 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
140 |
PRMT1 | interactor | 11 | 0.400 | 8.823 | Methyltransf_25 (PF13649): Methyltransferase domain |
141 |
PRPF4 | interactor | 7 | 0.533 | 4.620 | PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_like (PF17005, IPR031544): WD40-like domain |
142 |
PSEN1 | oncoprotein | 17 | 0.367 | 45.444 | Presenilin (PF01080, IPR001108): Presenilin LRRC37AB_C (PF14914, IPR029423): LRRC37A/B like protein 1 C-terminal domain |
143 |
PSKH2 | interactor | 4 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain |
144 |
PSME1 | interactor | 5 | 0.500 | 0.868 | PA28_alpha (PF02251, IPR003185): Proteasome activator pa28 alpha subunit PA28_beta (PF02252, IPR003186): Proteasome activator pa28 beta subunit RNase_H2-Ydr279 (PF09468, IPR019024): Ydr279p protein family (RNase H2 complex component) |
145 |
RAD23A | oncoprotein | 15 | 0.319 | 40.000 | UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
146 |
RAE1 | interactor | 6 | 0.467 | 4.206 | Exonuc_X-T_C (PF08411, IPR013620): Exonuclease C-terminal WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
147 |
RAF1 | oncoprotein | 22 | 0.452 | 35.667 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
148 |
RASSF3 | suppressor | 3 | 0.667 | 0.500 | RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain Nore1-SARAH (PF16517, IPR011524): Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain |
149 |
RHOBTB2 | suppressor | 6 | 0.700 | 1.000 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Ras (PF00071, IPR001806, SM00173): Ras family SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain |
150 |
RIPK3 | interactor | 3 | 0.667 | 0.167 | Pkinase (PF00069, IPR000719): Protein kinase domain TrbM (PF07424, IPR009989): TrbM MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c RHIM (PF12721, IPR025735): RIP homotypic interaction motif |
151 |
RNF32 | interactor | 24 | 0.360 | 84.255 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger) |
152 |
RPAP3 | interactor | 13 | 0.359 | 24.574 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat RPAP3_C (PF13877, IPR025986): Potential Monad-binding region of RPAP3 Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat |
153 |
RPS15A | interactor | 15 | 0.390 | 28.745 | Ribosomal_S8 (PF00410, IPR000630): Ribosomal protein S8 |
154 |
RPS2 | interactor | 15 | 0.495 | 20.628 | Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain |
155 |
RPS27 | interactor | 9 | 0.500 | 6.336 | Ribosomal_S27e (PF01667, IPR000592): Ribosomal protein S27 DUF3795 (PF12675, IPR024227): Protein of unknown function (DUF3795) |
156 |
RPS27L | interactor | 7 | 0.667 | 1.615 | E7 (PF00527, IPR000148): E7 protein, Early protein Ribosomal_S27e (PF01667, IPR000592): Ribosomal protein S27 zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type DUF3382 (PF11862, IPR021807): Domain of unknown function (DUF3382) |
157 |
RPS6KA1 | oncoprotein | 6 | 0.867 | 0.733 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
158 |
RPS6KA3 | interactor | 7 | 0.667 | 4.567 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
159 |
RPS6KA4 | interactor | 1 | 0 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
160 |
RPS6KA6 | suppressor | 6 | 0.467 | 6.367 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
161 |
RPS6KB2 | interactor | 32 | 0.280 | 149.228 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
162 |
RSG1 | interactor | 1 | 0 | 0 | Ras (PF00071, IPR001806, SM00173): Ras family |
163 |
RYK | oncoprotein | 5 | 0.600 | 1.241 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase WIF (PF02019, IPR003306, SM00469): WIF domain |
164 |
SAFB | suppressor | 4 | 1.000 | 0 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP (PF02037, IPR003034, SM00513): SAP domain Ferlin_C (PF16165, IPR032362): Ferlin C-terminus |
165 |
SGK1 | oncoprotein | 11 | 0.556 | 5.597 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain PX (PF00787, IPR001683, SM00312): PX domain |
166 |
SKP1 | oncoprotein | 16 | 0.250 | 58.197 | Skp1 (PF01466, IPR016072, SM00512): Skp1 family, dimerisation domain Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain |
167 |
SLC25A5 | interactor | 12 | 0.500 | 6.954 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
168 |
SLC25A6 | interactor | 8 | 0.393 | 4.630 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
169 |
SMYD2 | interactor | 4 | 0.667 | 0.216 | Complex1_LYR (PF05347, IPR008011): Complex 1 protein (LYR family) SET (PF00856, IPR001214, SM00317): SET domain TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat |
170 |
SMYD3 | oncoprotein | 4 | 0.833 | 0.077 | SET (PF00856, IPR001214, SM00317): SET domain |
171 |
SNX5 | oncoprotein | 2 | 1.000 | 0 | PX (PF00787, IPR001683, SM00312): PX domain Vps5 (PF09325, IPR015404): Vps5 C terminal like |
172 |
SPTBN4 | interactor | 3 | 0.667 | 0.667 | Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) Laminin_II (PF06009, IPR010307): Laminin Domain II Spectrin (PF00435, IPR002017): Spectrin repeat PH_9 (PF15410): Pleckstrin homology domain |
173 |
SQSTM1 | oncoprotein | 20 | 0.275 | 63.854 | PB1 (PF00564, IPR000270, SM00666): PB1 domain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type UBA_5 (PF16577, IPR015940): UBA domain |
174 |
SRC | oncoprotein | 16 | 0.552 | 13.834 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
175 |
SSB | interactor | 10 | 0.400 | 11.907 | HMA (PF00403, IPR006121): Heavy-metal-associated domain La (PF05383, IPR006630, SM00715): La domain Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family Ribosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 (PF08777, IPR014886): RNA binding motif |
176 |
STAMBPL1 | interactor | 5 | 0.900 | 0.154 | CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain USP8_dimer (PF08969, IPR015063): USP8 dimerisation domain JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
177 |
STIL | oncoprotein | 12 | 0.273 | 27.015 | STIL_N (PF15253, IPR026123): SCL-interrupting locus protein N-terminus |
178 |
STK11 | suppressor | 11 | 0.400 | 16.526 | Pkinase (PF00069, IPR000719): Protein kinase domain |
179 |
STK32C | interactor | 2 | 1.000 | 0 | APH (PF01636, IPR002575): Phosphotransferase enzyme family Pkinase (PF00069, IPR000719): Protein kinase domain |
180 |
STK33 | interactor | 4 | 0.833 | 0.077 | Pkinase (PF00069, IPR000719): Protein kinase domain PARM (PF17061, IPR031431): PARM |
181 |
STK36 | protein found in more fusions | 3 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
182 |
STK38L | oncoprotein | 3 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
183 |
STK4 | oncoprotein | 6 | 0.400 | 4.515 | Pkinase (PF00069, IPR000719): Protein kinase domain Mst1_SARAH (PF11629, IPR024205): C terminal SARAH domain of Mst1 DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611) |
184 |
STUB1 | suppressor | 39 | 0.248 | 269.696 | U-box (PF04564, IPR003613, SM00504): U-box domain ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_20 (PF14561): Tetratricopeptide repeat |
185 |
SYNE2 | oncoprotein | 4 | 0.667 | 1.667 | ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit Fez1 (PF06818): Fez1 Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Laminin_II (PF06009, IPR010307): Laminin Domain II Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein Occludin_ELL (PF07303, IPR010844): Occludin homology domain SlyX (PF04102, IPR007236): SlyX Spectrin (PF00435, IPR002017): Spectrin repeat TMPIT (PF07851, IPR012926): TMPIT-like protein KASH (PF10541, IPR012315): Nuclear envelope localisation domain HD_5 (PF13487): HD domain DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain DUF4363 (PF14276, IPR025373): Domain of unknown function (DUF4363) Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167 TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation TRPM_tetra (PF16519, IPR032415): Tetramerisation domain of TRPM |
186 |
TARS2 | interactor | 6 | 0.667 | 1.536 | HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain TGS (PF02824, IPR004095): TGS domain tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T) tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain |
187 |
TBK1 | interactor | 16 | 0.390 | 31.553 | DUF713 (PF05218, IPR007883): Protein of unknown function (DUF713) NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein Pkinase (PF00069, IPR000719): Protein kinase domain |
188 |
TERF1 | interactor | 22 | 0.248 | 94.026 | TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
189 |
TERF2 | interactor | 14 | 0.397 | 22.303 | Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain TERF2_RBM (PF16772, IPR031902): Telomeric repeat-binding factor 2 Rap1-binding motif |
190 |
TOMM34 | interactor | 12 | 0.470 | 11.617 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat SHNi-TPR (PF10516, IPR019544): SHNi-TPR TPR_12 (PF13424): Tetratricopeptide repeat Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat DUF4919 (PF16266, IPR032578): Domain of unknown function (DUF4919) |
191 |
TPM1 | protein found in more fusions | 11 | 0.356 | 14.179 | Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like |
192 |
TTC4 | suppressor | 12 | 0.515 | 15.287 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat |
193 |
TTC9C | interactor | 5 | 0.700 | 1.733 | TPR_17 (PF13431): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat |
194 |
TUBA1B | interactor | 12 | 0.303 | 26.343 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
195 |
TUBA1C | interactor | 18 | 0.444 | 34.277 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
196 |
TUBB | interactor | 30 | 0.425 | 80.400 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
197 |
U2AF2 | protein found in more fusions | 29 | 0.312 | 141.551 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
198 |
UBE2I | interactor | 16 | 0.257 | 47.567 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
199 |
ULK1 | protein found in more fusions | 6 | 0.600 | 3.167 | Pkinase (PF00069, IPR000719): Protein kinase domain DUF3543 (PF12063, IPR022708): Domain of unknown function (DUF3543) RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein |
200 |
ULK3 | interactor | 5 | 0.400 | 2.100 | MIT (PF04212, IPR007330, SM00745): MIT (microtubule interacting and transport) domain Pkinase (PF00069, IPR000719): Protein kinase domain |
201 |
UNC45A | interactor | 9 | 0.389 | 13.891 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat RIX1 (PF08167, IPR012583): rRNA processing/ribosome biogenesis TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central TPR_16 (PF13432): Tetratricopeptide repeat HEAT_2 (PF13646): HEAT repeats |
202 |
UPF1 | interactor | 12 | 0.318 | 27.599 | UPF1_Zn_bind (PF09416, IPR018999): RNA helicase (UPF2 interacting domain) AAA_11 (PF13086): AAA domain AAA_12 (PF13087): AAA domain |
203 |
USP19 | interactor | 15 | 0.314 | 40.842 | CS (PF04969, IPR007052): CS domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase USP19_linker (PF16602): Linker region of USP19 deubiquitinase |
204 |
USP7 | oncoprotein | 16 | 0.286 | 45.084 | MATH (PF00917, IPR002083, SM00061): MATH domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal |
205 |
VCP | protein found in more fusions | 35 | 0.296 | 195.249 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944) |
206 |
WDR6 | interactor | 6 | 0.533 | 4.571 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nsp3_PL2pro (PF12124, IPR022733): Coronavirus polyprotein cleavage domain Choline_sulf_C (PF12411, IPR025863): Choline sulfatase enzyme C terminal PQQ_3 (PF13570): PQQ-like domain |
207 |
YWHAE | oncoprotein | 30 | 0.287 | 140.430 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
208 |
YWHAQ | interactor | 31 | 0.275 | 164.913 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
209 |
ZNF205 | interactor | 1 | 0 | 0 | KRAB (PF01352, IPR001909, SM00349): KRAB box zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
210 |
ZNF235 | interactor | 1 | 0 | 0 | KRAB (PF01352, IPR001909, SM00349): KRAB box zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
211 |
ZNF266 | interactor | 1 | 0 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger FANCM-MHF_bd (PF16783, IPR031879): FANCM to MHF binding domain |
212 |
ZNF667 | interactor | 1 | 0 | 0 | KRAB (PF01352, IPR001909, SM00349): KRAB box zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain YhfH (PF14149, IPR025432): YhfH-like protein |