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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)89
The number (and %) of the onco-proteins24 (26.97 %)
The number (and %) of the tumor suppressors7 (7.87 %)
Total number of binary PPIs (saturation %)350 (8.94 %)
The number (and %) of affected PPIs89 (25.43 %)
The number of possible different fusions19
PPI diameter2
PPI radius1
The average degree of PPI7.169
Assortativity coefficient-0.2418
The network average Clustering coefficient0.582
The number (and %) of a zero Clustering coefficients9 (10.11 %)
The number (and %) of a zero Betweenness Centrality30 (33.71 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: CD2AP All fusions
: AI564093;
Proteins found in more fusions IMPDH2 (see 2 fusions); CD2AP (see 1 fusions); NF2 (see 1 fusions); KHDRBS1 (see 1 fusions); LMNA (see 3 fusions); SH3KBP1 (see 1 fusions); EGFR (see 2 fusions); CBL (see 1 fusions); SH3GL2 (see 1 fusions); NR3C1 (see 8 fusions); CTTN (see 1 fusions); TSC22D1 (see 4 fusions); HUWE1 (see 2 fusions); FRS3 (see 1 fusions); GRB2 (see 1 fusions); UBC (see 1 fusions); PRDX6 (see 1 fusions); CBLB (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 CD2APparental protein890.0605937.498SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil
2 ACTC1interactor40.8330.222Actin (PF00022, IPR004000, SM00268): Actin
3 ARHGAP17interactor60.6002.619BAR (PF03114, IPR004148, SM00721): BAR domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
4 ARHGEF10interactor100DUF883 (PF05957, IPR010279): Bacterial protein of unknown function (DUF883)
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
5 ASNSoncoprotein100.33324.586Asn_synthase (PF00733, IPR001962): Asparagine synthase
GATase_7 (PF13537, IPR000583): Glutamine amidotransferase domain
6 ATP6AP2interactor200Phosphodiest (PF01663, IPR002591): Type I phosphodiesterase / nucleotide pyrophosphatase
Renin_r (PF07850, IPR012493): Renin receptor-like protein
7 BCAR1oncoprotein50.7002.333Serine_rich (PF08824, IPR014928): Serine rich protein interaction domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF3513 (PF12026, IPR021901): Domain of unknown function (DUF3513)
Caskin1-CID (PF16600): Caskin1 CASK-interaction domain
8 BLNKsuppressor70.7142.252SH2 (PF00017, IPR000980, SM00252): SH2 domain
9 BRCC3interactor130.53018.800JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
10 CAPZA1interactor100.46712.700F-actin_cap_A (PF01267, IPR002189): F-actin capping protein alpha subunit
11 CAPZA2interactor120.36435.352F-actin_cap_A (PF01267, IPR002189): F-actin capping protein alpha subunit
12 CAPZBinteractor110.47316.241Cytochrom_B562 (PF07361, IPR009155): Cytochrome b562
F_actin_cap_B (PF01115, IPR001698): F-actin capping protein, beta subunit
13 CBLoncoprotein150.40733.594Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1
Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain
Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
14 CBLBoncoprotein71.0000Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1
Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain
Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
PRIMA1 (PF16101): Proline-rich membrane anchor 1
15 CBLConcoprotein40.6671.000Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1
Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain
Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
16 CCDC6oncoprotein41.0000CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DUF2046 (PF09755, IPR019152): Uncharacterized conserved protein H4 (DUF2046)
FAM199X (PF15814, IPR029672): Protein family FAM199X
17 CD2interactor31.0000C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
18 CSTF2interactor50.4004.500RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
CSTF_C (PF14304, IPR026896): Transcription termination and cleavage factor C-terminal
CSTF2_hinge (PF14327, IPR025742): Hinge domain of cleavage stimulation factor subunit 2
19 CTTNoncoprotein80.4766.800FadA (PF09403, IPR018543): Adhesion protein FadA
HS1_rep (PF02218, IPR003134): Repeat in HS1/Cortactin
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
20 DNM2interactor80.6074.675Dynamin_M (PF01031, IPR000375): Dynamin central region
GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain
PH (PF00169, IPR001849, SM00233): PH domain
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
21 DPH5interactor30.6671.000TP_methylase (PF00590, IPR000878): Tetrapyrrole (Corrin/Porphyrin) Methylases
22 EGFRoncoprotein180.29475.538Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
23 ELP2interactor50.5004.667WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Lar_restr_allev (PF14354): Restriction alleviation protein Lar
24 FRS3suppressor41.0000IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
25 GALEinteractor31.0000GDP_Man_Dehyd (PF16363, IPR016040): GDP-mannose 4,6 dehydratase
26 GRB2oncoprotein210.30583.346SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
27 GZMBinteractor30.6671.000Trypsin (PF00089, IPR001254, SM00020): Trypsin
28 HBP1interactor100AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH)
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
29 HNRNPRinteractor140.39642.767RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Limkain-b1 (PF11608, IPR024582): Limkain b1
30 HOXC11interactor100DUF3528 (PF12045, IPR021918): Protein of unknown function (DUF3528)
31 HUWE1oncoprotein140.32142.433BUD22 (PF09073, IPR015158): BUD22
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation
HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Nop14 (PF04147, IPR007276): Nop14-like family
PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
WWE (PF02825, IPR004170, SM00678): WWE domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
32 IKBKAPinteractor60.4005.167IKI3 (PF04762, IPR006849): IKI3 family
Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS
MMU163 (PF17119, IPR031342): Mitochondrial protein up-regulated during meiosis
33 IMPDH2protein found in more fusions50.6670.733IMPDH (PF00478, IPR001093): IMP dehydrogenase / GMP reductase domain
34 INPP5Dinteractor41.0000Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
SH2 (PF00017, IPR000980, SM00252): SH2 domain
35 ITGA4interactor170.30853.571FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
36 KHDRBS1protein found in more fusions50.6670.833KH_1 (PF00013, IPR004088, SM00322): KH domain
Qua1 (PF16274, IPR032571): Qua1 domain
Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68
37 KIAA0196interactor40.6671.667Strumpellin (PF10266, IPR019393): Hereditary spastic paraplegia protein strumpellin
38 KIAA1033interactor60.4678.000WASH-7_mid (PF14744, IPR028282): WASH complex subunit 7
WASH-7_N (PF14745, IPR028191): WASH complex subunit 7, N-terminal
WASH-7_C (PF14746, IPR028283): WASH complex subunit 7, C-terminal
39 KIF15interactor100Bcr-Abl_Oligo (PF09036, IPR015123): Bcr-Abl oncoprotein oligomerisation domain
DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
SlyX (PF04102, IPR007236): SlyX
STE (PF02200, IPR003120, SM00424): STE like transcription factor
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
FlxA (PF14282, IPR025577): FlxA-like protein
HMMR_C (PF15908, IPR031794): Hyaluronan mediated motility receptor C-terminal
40 KIF23interactor41.0000DUF730 (PF05325, IPR007989): Protein of unknown function (DUF730)
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
MKLP1_Arf_bdg (PF16540, IPR032384): Arf6-interacting domain of mitotic kinesin-like protein 1
41 LARP7interactor100.60013.667Agouti (PF05039, IPR007733, SM00792): Agouti protein
DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
La (PF05383, IPR006630, SM00715): La domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RRM_3 (PF08777, IPR014886): RNA binding motif
42 LMNAprotein found in more fusions100.33320.800Filament (PF00038, IPR001664): Intermediate filament protein
LTD (PF00932, IPR001322): Lamin Tail Domain
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
43 LOXoncoprotein31.0000Lysyl_oxidase (PF01186, IPR001695): Lysyl oxidase
44 MED4interactor50.7003.000Med4 (PF10018, IPR019258): Vitamin-D-receptor interacting Mediator subunit 4
45 MORF4L1P2interactor100NA
46 MSNoncoprotein51.0000DUF883 (PF05957, IPR010279): Bacterial protein of unknown function (DUF883)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
47 MTA2interactor80.7504.467BAH (PF01426, IPR001025, SM00439): BAH domain
ELM2 (PF01448, IPR000949): ELM2 domain
Resolvase (PF00239, IPR006119, SM00857): Resolvase, N terminal domain
DDA1 (PF10172, IPR018276): Det1 complexing ubiquitin ligase
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
GATA (PF00320, IPR000679, SM00401): GATA zinc finger
48 MVB12Ainteractor50.5004.667DUF2464 (PF10240, IPR018798): Protein of unknown function (DUF2464)
49 NF2oncoprotein50.6672.000ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
50 NIT1interactor31.0000CN_hydrolase (PF00795, IPR003010): Carbon-nitrogen hydrolase
51 NOLC1interactor31.0000DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
SRP40_C (PF05022, IPR007718): SRP40, C-terminal domain
Stm1_N (PF09598, IPR019084): Stm1
stn_TNFRSF12A (PF12191, IPR022316): Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain
NST1 (PF13945, IPR025279): Salt tolerance down-regulator
SEEEED (PF14797, IPR029394): Serine-rich region of AP3B1, clathrin-adaptor complex
DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611)
PAF (PF15715, IPR031444): PCNA-associated factor
IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
NuDC (PF16273, IPR032572): Nuclear distribution C domain
PHC2_SAM_assoc (PF16616): Unstructured region on Polyhomeotic-like protein 1 and 2
52 NPHS1interactor41.0000C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
DUF4643 (PF15485, IPR028004): Domain of unknown function (DUF4643)
53 NPHS2interactor31.0000P_C (PF06640, IPR010588): P protein C-terminus
Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
54 NPLOC4interactor70.5715.067NPL4 (PF05021, IPR007717): NPL4 family
zf-NPL4 (PF05020, IPR007716): NPL4 family, putative zinc binding region
UN_NPL4 (PF11543, IPR024682): Nuclear pore localisation protein NPL4
55 NR2C2suppressor200Flagellin_N (PF00669, IPR001029): Bacterial flagellin N-terminal helical region
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
56 NR3C1protein found in more fusions130.39432.733GCR (PF02155, IPR001409): Glucocorticoid receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
57 NR4A1suppressor40.6672.000zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
58 NRASinteractor100Ras (PF00071, IPR001806, SM00173): Ras family
59 NRBP1suppressor30.6670.667Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
60 PDCD6IPinteractor110.48914.175BRO1 (PF03097, IPR004328, SM01041): BRO1-like domain
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
ALIX_LYPXL_bnd (PF13949, IPR025304): ALIX V-shaped domain binding to HIV
61 PFDN2interactor100Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
62 PPA2interactor21.0000Pyrophosphatase (PF00719, IPR008162): Inorganic pyrophosphatase
63 PRDX6protein found in more fusions70.4007.133AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
64 PTGES3interactor50.6672.000CS (PF04969, IPR007052): CS domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
65 RAB4Aoncoprotein21.0000Ras (PF00071, IPR001806, SM00173): Ras family
66 RABEP2interactor120.50023.733Rab5-bind (PF09311, IPR015390): Rabaptin-like protein
Rabaptin (PF03528, IPR018514): Rabaptin
67 RACGAP1interactor60.7332.233RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
68 RPGRIP1Linteractor70.7143.619bZIP_1 (PF00170, IPR004827): bZIP transcription factor
C2 (PF00168, IPR000008, SM00239): C2 domain
DivIC (PF04977, IPR007060): Septum formation initiator
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
FtsL (PF04999, IPR011922): Cell division protein FtsL
T3SS_needle_F (PF09392, IPR021123): Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
C2-C2_1 (PF11618, IPR021656): First C2 domain of RPGR-interacting protein 1
BNIP2 (PF12496, IPR022181): Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
DUF4497 (PF14924): Protein of unknown function (DUF4497)
69 SCPEP1interactor40.5002.500Peptidase_S10 (PF00450, IPR001563): Serine carboxypeptidase
70 SEC24Cinteractor50.5003.556Gelsolin (PF00626, IPR007123): Gelsolin repeat
Sec23_BS (PF08033, IPR012990): Sec23/Sec24 beta-sandwich domain
Sec23_helical (PF04815, IPR006900): Sec23/Sec24 helical domain
Sec23_trunk (PF04811, IPR006896): Sec23/Sec24 trunk domain
zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger
71 SEC24Dinteractor31.0000Gelsolin (PF00626, IPR007123): Gelsolin repeat
Sec23_BS (PF08033, IPR012990): Sec23/Sec24 beta-sandwich domain
Sec23_helical (PF04815, IPR006900): Sec23/Sec24 helical domain
Sec23_trunk (PF04811, IPR006896): Sec23/Sec24 trunk domain
Transp_Tc5_C (PF04236, IPR007350): Tc5 transposase C-terminal domain
zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger
72 SH3BP1interactor21.0000BAR (PF03114, IPR004148, SM00721): BAR domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting
73 SH3GL2oncoprotein70.8000.952BAR (PF03114, IPR004148, SM00721): BAR domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
74 SH3KBP1protein found in more fusions370.141471.971Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein
SH3_9 (PF14604, IPR001452): Variant SH3 domain
75 SLC25A41interactor30.6670.667Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
76 SPAG9interactor80.6795.733DUF501 (PF04417, IPR007511): Protein of unknown function (DUF501)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
IncA (PF04156, IPR007285): IncA protein
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
UPF0449 (PF15136, IPR028227): Uncharacterised protein family UPF0449
JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
77 STAP1interactor41.0000PH (PF00169, IPR001849, SM00233): PH domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
78 TAS2R7interactor21.0000TAS2R (PF05296, IPR007960): Taste receptor protein (TAS2R)
79 TRAoncoprotein21.0000NA
80 TSC22D1suppressor50.5002.667SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
81 TSG101oncoprotein100.47213.119APG6 (PF04111, IPR007243): Autophagy protein Apg6
Laminin_II (PF06009, IPR010307): Laminin Domain II
UEV (PF05743, IPR008883): UEV domain
Vps23_core (PF09454, IPR017916): Vps23 core domain
82 TTC27interactor50.6002.500TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TraH (PF06122, IPR010927): Conjugative relaxosome accessory transposon protein
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
83 UBCprotein found in more fusions180.35357.875ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
84 UBE2Iinteractor70.4675.667UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
85 UFD1Linteractor80.46411.000UFD1 (PF03152, IPR004854): Ubiquitin fusion degradation protein UFD1
86 USP34interactor31.0000Secretin_N_2 (PF07655, IPR011514): Secretin N-terminal domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
DUF3517 (PF12030, IPR021905): Domain of unknown function (DUF3517)
87 VCAM1interactor140.34137.938C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
88 WDHD1interactor50.7003.000PVL_ORF50 (PF07768, IPR011688): PVL ORF-50-like family
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
Mcl1_mid (PF12341, IPR022100): Minichromosome loss protein, Mcl1, middle region
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein
89 ZYXsuppressor60.3339.000DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
LIM (PF00412, IPR001781, SM00132): LIM domain
DUF2757 (PF10955, IPR020115): Protein of unknown function (DUF2757)

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