Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins CBL (from a repository: Sun Dec 4 08:30:36 2016)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
Layout Tree Circle Radial Force Directed Preset
Export graph PNG file PDF file SVG file SIF file XML file GraphML file

Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 233 The number (and %) of the onco-proteins 86 (36.91 %) The number (and %) of the tumor suppressors 37 (15.88 %) Total number of binary PPIs (saturation %) 1959 (7.25 %) The number (and %) of affected PPIs 233 (11.89 %) The number of possible different fusions 39 PPI diameter 2 PPI radius 1 The average degree of PPI 16.043 Assortativity coefficient -0.2060 The network average Clustering coefficient 0.499 The number (and %) of a zero Clustering coefficients 6 (2.58 %) The number (and %) of a zero Betweenness Centrality 21 (9.01 %)

ACTIVE INTERACTORS

List of the fusions

Proteins found in more fusions

SYK (see 1 fusions); EEF1A1 (see 1 fusions); CBL (see 1 fusions); GRB2 (see 1 fusions); FYN (see 1 fusions); YWHAH (see 2 fusions); TNFRSF1A (see 2 fusions); UBE2D2 (see 2 fusions); ACTB (see 3 fusions); TRAF4 (see 1 fusions); YWHAZ (see 1 fusions); PIK3R1 (see 1 fusions); SORBS2 (see 4 fusions); UBC (see 1 fusions); FGFR2 (see 3 fusions); ITSN2 (see 1 fusions); PTPN11 (see 1 fusions); BCR/ABL1 (see 183 fusions); LYN (see 2 fusions); SH3GL2 (see 1 fusions); ACTN1 (see 3 fusions); FRS3 (see 1 fusions); LCK (see 1 fusions); MAPK14 (see 1 fusions); STAT3 (see 2 fusions); CD2AP (see 1 fusions); CD40 (see 2 fusions); ERBIN (see 4 fusions); SH3KBP1 (see 1 fusions); EGFR (see 2 fusions); SHC1 (see 1 fusions); EPS8 (see 1 fusions); PTK2 (see 2 fusions); TGM2 (see 4 fusions); PSMC5 (see 2 fusions); CBLB (see 4 fusions); SMAD3 (see 3 fusions); GAPDH (see 2 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	CBL	parental protein	233	0.061	32363.102	Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1 Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
2	ABI1	oncoprotein	7	0.714	1.853	Abi_HHR (PF07815, IPR012849): Abl-interactor HHR Cytochrom_B558a (PF05038, IPR007732): Cytochrome Cytochrome b558 alpha-subunit SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF4124 (PF13511, IPR025392): Domain of unknown function (DUF4124) PRIMA1 (PF16101): Proline-rich membrane anchor 1 ATP-synt_ab_Xtn (PF16886, IPR031686): ATPsynthase alpha/beta subunit N-term extension
3	ABL1	oncoprotein	46	0.302	289.826	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding SH3_1 (PF00018, IPR001452, SM00326): SH3 domain FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2
4	ACACA	interactor	8	0.714	1.141	ACC_central (PF08326, IPR013537): Acetyl-CoA carboxylase, central region Biotin_carb_C (PF02785, IPR005482, SM00878): Biotin carboxylase C-terminal domain Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme Carboxyl_trans (PF01039, IPR000022): Carboxyl transferase domain Biotin_carb_N (PF00289, IPR005481): Biotin carboxylase, N-terminal domain CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain DUF445 (PF04286, IPR007383): Protein of unknown function (DUF445)
5	ACTA1	interactor	12	0.424	18.483	Actin (PF00022, IPR004000, SM00268): Actin
6	ACTB	oncoprotein	19	0.451	39.797	Actin (PF00022, IPR004000, SM00268): Actin
7	ACTG2	interactor	1	0	0	Actin (PF00022, IPR004000, SM00268): Actin
8	ACTN1	protein found in more fusions	10	0.389	13.737	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Dak2 (PF02734, IPR004007, SM01120): DAK2 domain EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand Spectrin (PF00435, IPR002017): Spectrin repeat EF-hand_7 (PF13499, IPR011992): EF-hand domain pair Uds1 (PF15456, IPR029191): Up-regulated During Septation
9	APPL1	interactor	8	0.905	0.422	ATP-synt_E (PF05680, IPR008386): ATP synthase E chain Fzo_mitofusin (PF04799, IPR006884): fzo-like conserved region PH (PF00169, IPR001849, SM00233): PH domain PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) BAR_3 (PF16746): BAR domain of APPL family
10	ARHGEF6	oncoprotein	7	0.533	4.733	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1 PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_9 (PF14604, IPR001452): Variant SH3 domain betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil RhoGEF67_u2 (PF16614): Unstructured region two on RhoGEF 6 and 7 RhoGEF67_u1 (PF16615): Unstructured region one on RhoGEF 6 and 7
11	ARHGEF7	interactor	11	0.436	16.031	Borrelia_lipo_1 (PF05714, IPR008421): Borrelia burgdorferi virulent strain associated lipoprotein CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_2 (PF07653, IPR011511): Variant SH3 domain RhoGEF67_u2 (PF16614): Unstructured region two on RhoGEF 6 and 7 RhoGEF67_u1 (PF16615): Unstructured region one on RhoGEF 6 and 7
12	ASAP1	interactor	10	0.711	2.632	ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf PH (PF00169, IPR001849, SM00233): PH domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) BAR_3 (PF16746): BAR domain of APPL family
13	AXL	oncoprotein	6	0.733	0.627	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase DUF2627 (PF11118, IPR020138): Protein of unknown function (DUF2627) Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain
14	BAG1	oncoprotein	6	0.667	2.667	BAG (PF02179, IPR003103, SM00264): BAG domain Presenilin (PF01080, IPR001108): Presenilin ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
15	BCAR1	oncoprotein	30	0.308	127.120	Serine_rich (PF08824, IPR014928): Serine rich protein interaction domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF3513 (PF12026, IPR021901): Domain of unknown function (DUF3513) Caskin1-CID (PF16600): Caskin1 CASK-interaction domain
16	BCR	suppressor	23	0.383	67.072	Bcr-Abl_Oligo (PF09036, IPR015123): Bcr-Abl oncoprotein oligomerisation domain C2 (PF00168, IPR000008, SM00239): C2 domain PH (PF00169, IPR001849, SM00233): PH domain RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain IQ_SEC7_PH (PF16453, IPR001849): PH domain
17	BLK	oncoprotein	5	0.800	0.800	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
18	BLNK	suppressor	17	0.368	32.351	SH2 (PF00017, IPR000980, SM00252): SH2 domain
19	BTK	suppressor	20	0.251	68.623	BTK (PF00779, IPR001562, SM00107): BTK motif PH (PF00169, IPR001849, SM00233): PH domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
20	CAD	oncoprotein	14	0.582	10.048	Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 (PF02787, IPR005480, SM01096): Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_sm_chain (PF00988, IPR002474, SM01097): Carbamoyl-phosphate synthase small chain, CPSase domain GATase (PF00117, IPR017926): Glutamine amidotransferase class-I MGS (PF02142, IPR011607, SM00851): MGS-like domain OTCace (PF00185, IPR006131): Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N (PF02729, IPR006132): Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain ATPgrasp_Ter (PF15632, IPR011226): ATP-grasp in the biosynthetic pathway with Ter operon
21	CALM1	interactor	14	0.319	28.845	EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
22	CAPZA1	interactor	8	0.536	4.486	F-actin_cap_A (PF01267, IPR002189): F-actin capping protein alpha subunit
23	CBLB	oncoprotein	38	0.290	244.189	Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1 Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 PRIMA1 (PF16101): Proline-rich membrane anchor 1
24	CCT8	interactor	13	0.385	26.381	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
25	CD247	interactor	10	0.444	13.952	ITAM (PF02189, IPR003110, SM00077): Immunoreceptor tyrosine-based activation motif TCR_zetazeta (PF11628, IPR021663): T-cell surface glycoprotein CD3 zeta chain
26	CD2AP	protein found in more fusions	15	0.407	27.960	SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil
27	CD33	interactor	3	0.667	0.200	DUF998 (PF06197, IPR009339): Protein of unknown function (DUF998) ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain
28	CD38	interactor	4	1.000	0	Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain Rib_hydrolayse (PF02267, IPR003193): ADP-ribosyl cyclase
29	CD40	protein found in more fusions	7	0.467	5.019	Glycophorin_A (PF01102, IPR001195): Glycophorin A TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
30	CD5	interactor	6	0.800	0.500	SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain Comm (PF15957, IPR031878): Commissureless
31	CDC42	oncoprotein	16	0.267	46.775	Ras (PF00071, IPR001806, SM00173): Ras family
32	CEP128	interactor	10	0.311	17.236	DUF1129 (PF06570, IPR009214): Protein of unknown function (DUF1129) DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein SpoOE-like (PF09388, IPR018540): Spo0E like sporulation regulatory protein DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968) TraF_2 (PF13729, IPR032811): F plasmid transfer operon, TraF, protein GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) HAUS6_N (PF14661, IPR028163): HAUS augmin-like complex subunit 6 N-terminus HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
33	CEP170	interactor	17	0.338	45.475	FHA (PF00498, IPR000253, SM00240): FHA domain DUF4254 (PF14063, IPR025350): Protein of unknown function (DUF4254) CEP170_C (PF15308, IPR029300): CEP170 C-terminus
34	CFTR	suppressor	12	0.400	17.994	ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region ABC_tran (PF00005, IPR003439): ABC transporter Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain
35	CORO1C	oncoprotein	10	0.667	4.625	DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat WD40_4 (PF16300): Type of WD40 repeat
36	CRK	oncoprotein	67	0.199	825.486	SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
37	CRKL	oncoprotein	28	0.394	80.443	SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
38	CSF1	oncoprotein	3	0.667	1.000	CSF-1 (PF05337, IPR008001): Macrophage colony stimulating factor-1 (CSF-1)
39	CSF1R	oncoprotein	14	0.341	31.615	ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain
40	CSK	interactor	12	0.576	10.595	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
41	CTNNB1	oncoprotein	27	0.242	149.350	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat
42	CUBN	oncoprotein	3	1.000	0	B1 (PF02246, IPR003147): Protein L b1 domain CUB (PF00431, IPR000859, SM00042): CUB domain EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like EGF_3 (PF12947, IPR024731): EGF domain FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
43	DBNL	interactor	4	0.667	0.452	RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 Rrn6 (PF10214, IPR019350): RNA polymerase I-specific transcription-initiation factor Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein SH3_9 (PF14604, IPR001452): Variant SH3 domain
44	EEF1A1	suppressor	21	0.453	42.226	GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
45	EGFR	oncoprotein	94	0.157	2094.673	Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
46	EPHA2	suppressor	11	0.689	6.150	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
47	EPHA8	interactor	3	0.667	1.000	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
48	EPHB1	interactor	4	0.667	0.533	EGF_2 (PF07974, IPR013111): EGF-like domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain cEGF (PF12662, IPR026823): Complement Clr-like EGF-like EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
49	EPOR	oncoprotein	16	0.508	19.616	EpoR_lig-bind (PF09067, IPR015152): Erythropoietin receptor, ligand binding fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
50	EPS8	oncoprotein	11	0.400	19.402	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator PTB (PF08416, IPR013625): Phosphotyrosine-binding domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
51	ERBB2	oncoprotein	42	0.272	284.491	Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
52	ERBB4	suppressor	15	0.604	12.775	Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain DUF3951 (PF13131, IPR025028): Protein of unknown function (DUF3951) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
53	ERBIN	oncoprotein	13	0.318	29.738	LRR_1 (PF00560, IPR001611): Leucine Rich Repeat Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat
54	FBF1	interactor	8	0.393	12.117	DUF737 (PF05300, IPR007964): Protein of unknown function (DUF737) OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Sacchrp_dh_NADP (PF03435, IPR005097): Saccharopine dehydrogenase NADP binding domain Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80 Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14 Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family YlqD (PF11068, IPR021297): YlqD protein KfrA_N (PF11740, IPR021104): Plasmid replication region DNA-binding N-term
55	FCGR2A	interactor	9	0.417	12.472	DUF3827 (PF12877, IPR024606): Domain of unknown function (DUF3827) Ig_2 (PF13895, IPR007110): Immunoglobulin domain ECSCR (PF15820, IPR026247): Endothelial cell-specific chemotaxis regulator
56	FGFR2	oncoprotein	10	0.361	11.785	Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain
57	FGR	oncoprotein	8	0.714	1.354	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
58	FLOT1	interactor	12	0.227	33.090	CrtC (PF07143, IPR010791): CrtC N-terminal lipocalin domain Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family Flot (PF15975, IPR031905): Flotillin
59	FLT1	oncoprotein	5	0.700	0.972	C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain
60	FLT3	suppressor	5	0.667	0.444	I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ig_3 (PF13927): Immunoglobulin domain EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
61	FRS2	interactor	12	0.439	18.296	IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
62	FRS3	suppressor	8	0.524	3.982	IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
63	FYB	interactor	6	0.667	2.722	PRP1_N (PF06424, IPR010491): PRP1 splicing factor, N-terminal SH3_2 (PF07653, IPR011511): Variant SH3 domain hSH3 (PF14603, IPR029294): Helically-extended SH3 domain DUF4651 (PF15513, IPR028105): Domain of unknown function (DUF4651)
64	FYN	oncoprotein	38	0.218	276.900	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
65	GAPDH	oncoprotein	19	0.451	40.224	Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain OstA (PF03968, IPR005653): OstA-like protein
66	GAPVD1	interactor	6	0.600	1.806	RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase VPS9 (PF02204, IPR003123, SM00167): Vacuolar sorting protein 9 (VPS9) domain
67	GBA	interactor	5	0.600	1.519	Glyco_hydro_30 (PF02055, IPR001139): Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C (PF17189): Glycosyl hydrolase family 30 beta sandwich domain
68	GIF	interactor	2	1.000	0	Cobalamin_bind (PF01122, IPR002157): Eukaryotic cobalamin-binding protein Gemini_AL3 (PF01407, IPR000657): Geminivirus AL3 protein DUF4430 (PF14478, IPR027954): Domain of unknown function (DUF4430)
69	GRAP2	interactor	14	0.341	23.684	NADH_dhqG_C (PF09326, IPR015405): NADH-ubiquinone oxidoreductase subunit G, C-terminal SH2 (PF00017, IPR000980, SM00252): SH2 domain DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076) SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
70	GRB2	oncoprotein	109	0.144	2804.427	SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
71	HCK	oncoprotein	16	0.392	26.571	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
72	HRAS	oncoprotein	9	0.361	13.644	Ras (PF00071, IPR001806, SM00173): Ras family
73	HSPA1B	interactor	14	0.549	12.280	HSP70 (PF00012, IPR013126): Hsp70 protein
74	HSPA1L	interactor	13	0.551	9.473	HSP70 (PF00012, IPR013126): Hsp70 protein
75	HSPA4	interactor	23	0.225	124.581	Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
76	HSPA5	oncoprotein	28	0.393	78.147	HSP70 (PF00012, IPR013126): Hsp70 protein
77	HSPA6	interactor	11	0.691	4.166	HSP70 (PF00012, IPR013126): Hsp70 protein
78	HSPA8	oncoprotein	34	0.355	156.864	HSP70 (PF00012, IPR013126): Hsp70 protein
79	HSPA9	oncoprotein	12	0.742	3.165	HSP70 (PF00012, IPR013126): Hsp70 protein
80	HTR2A	interactor	2	1.000	0	7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) MscL (PF01741, IPR001185): Large-conductance mechanosensitive channel, MscL
81	IGF1R	oncoprotein	16	0.575	13.874	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain
82	IL7R	interactor	5	0.500	2.156	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
83	INPP5D	interactor	16	0.533	14.384	Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family SH2 (PF00017, IPR000980, SM00252): SH2 domain
84	INPPL1	oncoprotein	44	0.288	296.197	Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) SH2 (PF00017, IPR000980, SM00252): SH2 domain
85	IQGAP1	interactor	32	0.278	185.170	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF87 (PF01935, IPR002789): Domain of unknown function DUF87 IDEAL (PF08858, IPR014957, SM00914): IDEAL domain IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase RasGAP_C (PF03836, IPR000593): RasGAP C-terminus WW (PF00397, IPR001202, SM00456): WW domain
86	IRF1	suppressor	2	1.000	0	IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor
87	IRF8	suppressor	4	0.667	1.000	IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3
88	IRS1	interactor	21	0.424	44.556	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) PH (PF00169, IPR001849, SM00233): PH domain
89	ITCH	interactor	23	0.203	129.070	C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
90	ITGA4	interactor	38	0.222	255.573	FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
91	ITGA5	suppressor	3	0.667	1.000	FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha VCBS (PF13517): Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
92	ITGAV	suppressor	7	0.381	5.275	FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha VCBS (PF13517): Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Collectrin (PF16959, IPR031588): Renal amino acid transporter
93	ITK	oncoprotein	11	0.756	1.902	BTK (PF00779, IPR001562, SM00107): BTK motif PH (PF00169, IPR001849, SM00233): PH domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
94	ITSN1	interactor	14	0.333	28.440	C2 (PF00168, IPR000008, SM00239): C2 domain VIT1 (PF01988, IPR008217): VIT family DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) FmdE (PF02663, IPR003814): FmdE, Molybdenum formylmethanofuran dehydrogenase operon GSH_synthase (PF03199, IPR004887): Eukaryotic glutathione synthase RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) SH3_9 (PF14604, IPR001452): Variant SH3 domain DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748) INTAP (PF16617): Intersectin and clathrin adaptor AP2 binding region PH_13 (PF16652, IPR001849): Pleckstrin homology domain
95	ITSN2	protein found in more fusions	8	0.619	4.033	C2 (PF00168, IPR000008, SM00239): C2 domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) SH3_9 (PF14604, IPR001452): Variant SH3 domain MRP-S26 (PF14943, IPR026140): Mitochondrial ribosome subunit S26 VIR_N (PF15912, IPR031801): Virilizer, N-terminal PH_13 (PF16652, IPR001849): Pleckstrin homology domain
96	KDR	oncoprotein	8	0.679	3.741	Ehrlichia_rpt (PF09528, IPR019048): Ehrlichia tandem repeat (Ehrlichia_rpt) Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
97	KIT	oncoprotein	19	0.433	34.721	ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain
98	KRT1	interactor	14	0.736	5.312	Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region Keratin_2_head (PF16208, IPR032444): Keratin type II head Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail
99	KRT10	interactor	14	0.714	6.840	Filament (PF00038, IPR001664): Intermediate filament protein FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
100	KRT14	interactor	11	0.709	5.090	Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region Keratin_2_head (PF16208, IPR032444): Keratin type II head
101	KRT16	interactor	10	0.889	0.630	Filament (PF00038, IPR001664): Intermediate filament protein zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein Keratin_2_head (PF16208, IPR032444): Keratin type II head
102	KRT17	interactor	9	0.806	1.571	DUF1798 (PF08807, IPR014913): Bacterial domain of unknown function (DUF1798) Filament (PF00038, IPR001664): Intermediate filament protein
103	KRT18	interactor	8	0.429	6.880	Filament (PF00038, IPR001664): Intermediate filament protein Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
104	KRT2	interactor	11	0.873	1.357	Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head
105	KRT3	interactor	7	0.762	3.400	Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head
106	KRT5	interactor	15	0.648	17.041	Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head
107	KRT6A	interactor	7	0.810	0.713	Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head
108	KRT6B	interactor	4	1.000	0	Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head
109	KRT6C	interactor	3	1.000	0	Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head
110	KRT79	interactor	5	0.900	0.067	Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head
111	KRT84	interactor	1	0	0	Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head
112	KRT9	interactor	10	0.822	0.883	Filament (PF00038, IPR001664): Intermediate filament protein FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
113	LAT	interactor	19	0.480	36.569	LAT (PF15234, IPR008359): Linker for activation of T-cells
114	LCK	oncoprotein	27	0.240	131.489	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
115	LCP2	interactor	20	0.447	42.107	SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) SDA1 (PF05285, IPR007949): SDA1 SH2 (PF00017, IPR000980, SM00252): SH2 domain
116	LOX	suppressor	3	1.000	0	Lysyl_oxidase (PF01186, IPR001695): Lysyl oxidase
117	LRIG1	suppressor	5	0.800	0.533	I-set (PF07679, IPR013098): Immunoglobulin I-set domain LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRR_2 (PF07723, IPR013101): Leucine Rich Repeat LRRCT (PF01463, IPR000483, SM00082): Leucine rich repeat C-terminal domain LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat Ig_3 (PF13927): Immunoglobulin domain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
118	LTK	interactor	3	0.667	0.095	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Gly_rich (PF12810): Glycine rich protein FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
119	LYN	oncoprotein	27	0.283	101.119	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
120	MAP3K11	interactor	5	0.500	1.833	APG6 (PF04111, IPR007243): Autophagy protein Apg6 Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH3_9 (PF14604, IPR001452): Variant SH3 domain
121	MAPK14	oncoprotein	11	0.311	13.947	Pkinase (PF00069, IPR000719): Protein kinase domain
122	MAPK8	oncoprotein	17	0.300	40.008	DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530) Pkinase (PF00069, IPR000719): Protein kinase domain
123	MET	oncoprotein	13	0.513	11.185	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase PSI (PF01437, IPR002165, SM00423): Plexin repeat Sema (PF01403, IPR001627, SM00630): Sema domain TIG (PF01833, IPR002909): IPT/TIG domain
124	MST1R	suppressor	12	0.576	9.781	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase PSI (PF01437, IPR002165, SM00423): Plexin repeat Sema (PF01403, IPR001627, SM00630): Sema domain TIG (PF01833, IPR002909): IPT/TIG domain
125	MYH10	interactor	13	0.526	9.829	IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
126	MYH2	interactor	3	0.667	0.333	IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail XhlA (PF10779, IPR019715): Haemolysin XhlA Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
127	MYH9	suppressor	28	0.320	131.128	IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
128	MYO1C	interactor	17	0.456	30.469	IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
129	MZF1	interactor	1	0	0	SCAN (PF02023, IPR003309, SM00431): SCAN domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
130	NCK1	oncoprotein	23	0.364	61.817	SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain
131	NCK2	interactor	22	0.267	81.151	SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain
132	NOTCH1	suppressor	11	0.333	17.272	Ank (PF00023, IPR002110, SM00248): Ankyrin repeat EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_2 (PF07974, IPR013111): EGF-like domain EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain NOD (PF06816, IPR010660): NOTCH protein NODP (PF07684, IPR011656): NOTCH protein TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Notch (PF00066, IPR000800, SM00004): LNR domain DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454) hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
133	NOTCH3	suppressor	5	0.500	4.067	Ank (PF00023, IPR002110, SM00248): Ankyrin repeat EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain NOD (PF06816, IPR010660): NOTCH protein NODP (PF07684, IPR011656): NOTCH protein Notch (PF00066, IPR000800, SM00004): LNR domain DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454) hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies)
134	NPHP1	interactor	8	0.381	5.977	SH3_1 (PF00018, IPR001452, SM00326): SH3 domain FAM176 (PF14851): FAM176 family Speriolin_N (PF15058, IPR029385): Speriolin N terminus DUF4746 (PF15928, IPR031827): Domain of unknown function (DUF4746)
135	NTRK1	oncoprotein	77	0.164	1399.528	I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
136	OSTF1	interactor	4	0.500	0.952	SH3_1 (PF00018, IPR001452, SM00326): SH3 domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
137	PDGFRA	oncoprotein	15	0.462	19.576	Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ig_3 (PF13927): Immunoglobulin domain LAT (PF15234, IPR008359): Linker for activation of T-cells
138	PIK3CA	oncoprotein	16	0.383	39.160	PI3K_C2 (PF00792, IPR002420, SM00142): Phosphoinositide 3-kinase C2 PI3K_p85B (PF02192, IPR003113, SM00143): PI3-kinase family, p85-binding domain PI3K_rbd (PF00794, IPR000341, SM00144): PI3-kinase family, ras-binding domain PI3Ka (PF00613, IPR001263, SM00145): Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF2321 (PF10083, IPR016891): Uncharacterized protein conserved in bacteria (DUF2321) PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
139	PIK3CB	oncoprotein	11	0.691	3.827	PI3K_C2 (PF00792, IPR002420, SM00142): Phosphoinositide 3-kinase C2 PI3K_p85B (PF02192, IPR003113, SM00143): PI3-kinase family, p85-binding domain PI3K_rbd (PF00794, IPR000341, SM00144): PI3-kinase family, ras-binding domain PI3Ka (PF00613, IPR001263, SM00145): Phosphoinositide 3-kinase family, accessory domain (PIK domain) RWD (PF05773, IPR006575, SM00591): RWD domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase Tom37_C (PF11801, IPR019564): Tom37 C-terminal domain DUF4381 (PF14316, IPR025489): Domain of unknown function (DUF4381)
140	PIK3R1	oncoprotein	56	0.253	558.363	RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain
141	PIK3R2	oncoprotein	54	0.244	481.325	RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain
142	PIK3R3	interactor	20	0.458	36.613	SH2 (PF00017, IPR000980, SM00252): SH2 domain PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain
143	PLCG1	oncoprotein	30	0.317	131.936	C2 (PF00168, IPR000008, SM00239): C2 domain PH (PF00169, IPR001849, SM00233): PH domain SH2 (PF00017, IPR000980, SM00252): SH2 domain PI-PLC-X (PF00388, IPR000909, SM00148): Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y (PF00387, IPR001711, SM00149): Phosphatidylinositol-specific phospholipase C, Y domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain PH_12 (PF16457, IPR001849): Pleckstrin homology domain
144	POP1	interactor	4	1.000	0	POP1 (PF06978, IPR009723): Ribonucleases P/MRP protein subunit POP1 POPLD (PF08170, IPR012590): POPLD (NUC188) domain
145	PRKCA	interactor	6	1.000	0	C2 (PF00168, IPR000008, SM00239): C2 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
146	PRKCQ	interactor	7	0.533	3.252	Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
147	PRPSAP2	interactor	4	0.833	0.182	Pribosyltran_N (PF13793, IPR029099): N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth (PF14572, IPR005946): Phosphoribosyl synthetase-associated domain
148	PSMC1	interactor	7	0.524	4.142	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) DivIC (PF04977, IPR007060): Septum formation initiator DUF815 (PF05673, IPR008533): Protein of unknown function (DUF815) Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain
149	PSMC5	protein found in more fusions	11	0.444	13.869	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) Laminin_II (PF06009, IPR010307): Laminin Domain II RILP (PF11461, IPR021563): Rab interacting lysosomal protein AAA_16 (PF13191): AAA ATPase domain
150	PTEN	suppressor	29	0.145	204.569	DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
151	PTK2	protein found in more fusions	37	0.343	157.453	FERM_M (PF00373, IPR019748): FERM central domain Focal_AT (PF03623, IPR005189): Focal adhesion targeting region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase UCMA (PF17085, IPR031386): Unique cartilage matrix associated protein
152	PTK2B	interactor	22	0.395	58.414	FERM_M (PF00373, IPR019748): FERM central domain Focal_AT (PF03623, IPR005189): Focal adhesion targeting region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
153	PTPN11	suppressor	31	0.354	125.252	SH2 (PF00017, IPR000980, SM00252): SH2 domain Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
154	PTPN22	interactor	10	0.472	8.641	Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
155	PTPN6	suppressor	22	0.394	61.729	SH2 (PF00017, IPR000980, SM00252): SH2 domain Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase PolyA_pol_arg_C (PF12626, IPR025866): Polymerase A arginine-rich C-terminus
156	PXN	oncoprotein	22	0.398	49.291	LIM (PF00412, IPR001781, SM00132): LIM domain Paxillin (PF03535): Paxillin family
157	RAPGEF1	oncoprotein	9	0.806	1.246	RasGEF (PF00617, IPR001895, SM00147): RasGEF domain RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif
158	RET	oncoprotein	13	0.667	9.038	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
159	RPS19	interactor	8	0.714	1.247	Ribosomal_S19e (PF01090, IPR001266): Ribosomal protein S19e
160	SERPINA5	interactor	2	1.000	0	Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
161	SFN	suppressor	22	0.319	64.790	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
162	SH2B2	oncoprotein	9	0.679	2.602	PH (PF00169, IPR001849, SM00233): PH domain Phe_ZIP (PF08916, IPR015012): Phenylalanine zipper SH2 (PF00017, IPR000980, SM00252): SH2 domain
163	SH3BP2	oncoprotein	14	0.538	15.153	PH (PF00169, IPR001849, SM00233): PH domain SH2 (PF00017, IPR000980, SM00252): SH2 domain
164	SH3GL2	oncoprotein	10	0.472	10.119	BAR (PF03114, IPR004148, SM00721): BAR domain SH3_2 (PF07653, IPR011511): Variant SH3 domain
165	SH3GL3	interactor	7	0.533	5.119	BAR (PF03114, IPR004148, SM00721): BAR domain SH3_2 (PF07653, IPR011511): Variant SH3 domain
166	SH3KBP1	protein found in more fusions	38	0.269	255.699	Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein SH3_9 (PF14604, IPR001452): Variant SH3 domain
167	SHC1	oncoprotein	73	0.187	993.276	PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) SH2 (PF00017, IPR000980, SM00252): SH2 domain
168	SIRT2	suppressor	4	0.500	1.619	SIR2 (PF02146, IPR003000): Sir2 family RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding
169	SLA	interactor	10	0.533	9.494	SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
170	SLA2	interactor	6	0.533	5.071	SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
171	SMAD3	oncoprotein	17	0.242	55.849	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
172	SMAD7	interactor	8	0.464	10.456	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
173	SNX18	interactor	5	0.600	1.230	PX (PF00787, IPR001683, SM00312): PX domain BAR_3_WASP_bdg (PF10456, IPR019497): WASP-binding domain of Sorting nexin protein SH3_9 (PF14604, IPR001452): Variant SH3 domain
174	SORBS1	interactor	13	0.372	23.870	SH3_2 (PF07653, IPR011511): Variant SH3 domain Sorb (PF02208, IPR003127, SM00459): Sorbin homologous domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain SCAB-ABD (PF16711, IPR032012): Actin-binding domain of plant-specific actin-binding protein
175	SORBS2	oncoprotein	16	0.362	31.508	Sorb (PF02208, IPR003127, SM00459): Sorbin homologous domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain
176	SORBS3	interactor	5	0.500	2.333	Sorb (PF02208, IPR003127, SM00459): Sorbin homologous domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain
177	SOS1	oncoprotein	30	0.322	130.369	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 PH (PF00169, IPR001849, SM00233): PH domain RasGEF (PF00617, IPR001895, SM00147): RasGEF domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif
178	SP7	interactor	2	1.000	0	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
179	SPRY1	interactor	8	0.536	4.037	PAP1 (PF08601, IPR013910): Transcription factor PAP1 Sprouty (PF05210, IPR007875): Sprouty protein (Spry)
180	SPRY2	suppressor	15	0.264	42.484	KAR9 (PF08580, IPR013889): Yeast cortical protein KAR9 Sprouty (PF05210, IPR007875): Sprouty protein (Spry)
181	SPRY4	suppressor	3	1.000	0	Sprouty (PF05210, IPR007875): Sprouty protein (Spry)
182	SPTA1	interactor	7	0.476	3.433	EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand Spectrin (PF00435, IPR002017): Spectrin repeat SH3_1 (PF00018, IPR001452, SM00326): SH3 domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
183	SPTAN1	oncoprotein	14	0.582	12.781	EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand Spectrin (PF00435, IPR002017): Spectrin repeat SH3_1 (PF00018, IPR001452, SM00326): SH3 domain Tetrabrachion (PF11401, IPR021535): Tetrabrachion EF-hand_7 (PF13499, IPR011992): EF-hand domain pair E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
184	SPTBN1	suppressor	14	0.571	14.784	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2 DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Spectrin (PF00435, IPR002017): Spectrin repeat PH_9 (PF15410): Pleckstrin homology domain
185	SRC	oncoprotein	39	0.306	207.815	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
186	SSFA2	interactor	8	0.607	2.942	KRAP_IP3R_bind (PF14722, IPR029325): Ki-ras-induced actin-interacting protein-IP3R-interacting domain SSFA2_C (PF14723, IPR029326): Sperm-specific antigen 2 C-terminus
187	STAP2	interactor	4	0.667	0.404	SH2 (PF00017, IPR000980, SM00252): SH2 domain
188	STAT3	suppressor	27	0.338	93.607	SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
189	STAT5A	suppressor	12	0.455	14.875	SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
190	SYK	suppressor	40	0.313	192.958	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain
191	SYNM	suppressor	4	0.667	0.619	Filament (PF00038, IPR001664): Intermediate filament protein CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
192	TCN1	interactor	1	0	0	Cobalamin_bind (PF01122, IPR002157): Eukaryotic cobalamin-binding protein DUF4430 (PF14478, IPR027954): Domain of unknown function (DUF4430)
193	TCN2	interactor	1	0	0	Cobalamin_bind (PF01122, IPR002157): Eukaryotic cobalamin-binding protein DUF4430 (PF14478, IPR027954): Domain of unknown function (DUF4430)
194	TEK	oncoprotein	1	0	0	EGF_2 (PF07974, IPR013111): EGF-like domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) Ig_Tie2_1 (PF10430, IPR018941): Tie-2 Ig-like domain 1 Ig_3 (PF13927): Immunoglobulin domain Pur_ac_phosph_N (PF16656, IPR015914): Purple acid Phosphatase, N-terminal domain
195	TGFBR2	suppressor	15	0.314	43.099	ecTbetaR2 (PF08917, IPR015013): Transforming growth factor beta receptor 2 ectodomain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
196	TGM2	protein found in more fusions	8	0.476	4.483	Transglut_C (PF00927, IPR008958): Transglutaminase family, C-terminal ig like domain Transglut_N (PF00868, IPR001102): Transglutaminase family Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily
197	TNFRSF10A	suppressor	2	1.000	0	Death (PF00531, IPR000488, SM00005): Death domain TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region TMIE (PF16038, IPR032006): TMIE protein
198	TNFRSF10B	suppressor	6	0.667	4.333	Death (PF00531, IPR000488, SM00005): Death domain RskA (PF10099, IPR018764): Anti-sigma-K factor rskA TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
199	TNFRSF1A	oncoprotein	14	0.551	12.970	Death (PF00531, IPR000488, SM00005): Death domain TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
200	TNS4	interactor	4	0.833	0.222	PTB (PF08416, IPR013625): Phosphotyrosine-binding domain SH2 (PF00017, IPR000980, SM00252): SH2 domain
201	TRAF4	oncoprotein	8	0.381	7.286	MATH (PF00917, IPR002083, SM00061): MATH domain Sina (PF03145, IPR018121): Seven in absentia protein family zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
202	TRIM21	interactor	10	0.472	14.071	DUF313 (PF03754, IPR005508): Domain of unknown function (DUF313) SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain Prok-RING_1 (PF14446): Prokaryotic RING finger family 1 zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
203	TRIM8	interactor	9	0.393	10.700	dCache_2 (PF08269, IPR004010, SM01049): Cache domain CASP_C (PF08172, IPR012955): CASP C terminal zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Zn_ribbon_recom (PF13408, IPR025827): Recombinase zinc beta ribbon domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
204	TRPV1	oncoprotein	4	1.000	0	Ion_trans (PF00520, IPR005821): Ion transport protein Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies)
205	TUBA1A	oncoprotein	20	0.421	42.594	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
206	TUBA1C	interactor	17	0.478	26.694	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
207	TUBA4B	interactor	9	0.861	0.936	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
208	TUBB	interactor	29	0.406	85.980	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
209	TUBB4B	interactor	18	0.542	20.183	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
210	TYK2	interactor	11	0.311	16.241	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
211	UBASH3A	interactor	8	0.667	3.138	His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1) UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain Ste5 (PF11610, IPR021651): Scaffold protein Ste5-Fus5 binding region SH3_9 (PF14604, IPR001452): Variant SH3 domain
212	UBASH3B	interactor	46	0.230	376.170	His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1) UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain 2_5_RNA_ligase2 (PF13563): 2'-5' RNA ligase superfamily SH3_9 (PF14604, IPR001452): Variant SH3 domain
213	UBC	protein found in more fusions	38	0.237	304.969	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
214	UBE2D1	interactor	11	0.489	10.383	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
215	UBE2D2	oncoprotein	14	0.385	30.921	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
216	UBE2D3	interactor	8	0.429	5.238	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
217	UBE2L3	interactor	11	0.400	16.756	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
218	UBE2M	interactor	4	0.667	0.500	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
219	UBE4B	suppressor	8	0.429	7.119	DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region Ufd2P_core (PF10408, IPR019474): Ubiquitin elongating factor core U-box (PF04564, IPR003613, SM00504): U-box domain DUF4568 (PF15132, IPR027919): Domain of unknown function (DUF4568)
220	USP21	interactor	5	0.500	1.486	UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
221	VAV1	oncoprotein	29	0.337	126.965	PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH2 (PF00017, IPR000980, SM00252): SH2 domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 (PF00018, IPR001452, SM00326): SH3 domain CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain
222	VAV2	oncoprotein	12	0.439	19.262	PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain CotJB (PF12652, IPR024207): CotJB protein
223	VIM	suppressor	13	0.394	20.128	Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
224	WAS	oncoprotein	22	0.338	66.156	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain WH1 (PF00568, IPR000697, SM00461): WH1 domain WH2 (PF02205, IPR003124, SM00246): WH2 motif PRIMA1 (PF16101): Proline-rich membrane anchor 1
225	XPO1	interactor	29	0.278	156.598	CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
226	XRCC5	suppressor	10	0.389	12.744	Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind (PF08785, IPR014893): Ku C terminal domain like
227	YES1	oncoprotein	9	0.389	8.711	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain YdjC (PF04794, IPR006879): YdjC-like protein SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
228	YWHAB	interactor	24	0.417	60.461	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein Virulence_fact (PF13769, IPR025989): Virulence factor
229	YWHAE	oncoprotein	28	0.299	134.185	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
230	YWHAH	protein found in more fusions	15	0.604	14.256	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
231	YWHAQ	interactor	35	0.286	226.495	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
232	YWHAZ	protein found in more fusions	28	0.362	104.648	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
233	ZAP70	interactor	28	0.359	111.499	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain

B a c k    t o    T o p ⇑