1 |
BCL6 | parental protein | 111 | 0.047 | 10050.765 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding DZR (PF12773, IPR025874): Double zinc ribbon zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger |
2 |
AES | protein found in more fusions | 6 | 0.400 | 5.667 | TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain |
3 |
ARHGAP35 | interactor | 1 | 0 | 0 | FF (PF01846, IPR002713, SM00441): FF domain Ras (PF00071, IPR001806, SM00173): Ras family RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain RhoGAP-FF1 (PF16512, IPR032835): p190-A and -B Rho GAPs FF domain |
4 |
ARNT2 | interactor | 5 | 0.500 | 4.067 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold PAP2 (PF01569, IPR000326, SM00014): PAP2 superfamily |
5 |
ATF7 | interactor | 4 | 0.667 | 0.833 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type |
6 |
BACH2 | oncoprotein | 3 | 0.667 | 1.000 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor |
7 |
BCL11A | oncoprotein | 5 | 1.000 | 0 | BSP_II (PF05432, IPR008412): Bone sialoprotein II (BSP-II) C1_4 (PF07975, IPR004595, SM01047): TFIIH C1-like domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-HIT (PF04438, IPR007529): HIT zinc finger zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain |
8 |
BCL6B | suppressor | 3 | 1.000 | 0 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain Lar_restr_allev (PF14354): Restriction alleviation protein Lar |
9 |
BCOR | oncoprotein | 9 | 0.536 | 6.648 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) BCOR (PF15808, IPR031628): BCL-6 co-repressor, non-ankyrin-repeat region PUFD (PF16553, IPR032365): BCORL-PCGF1-binding domain |
10 |
BLZF1 | interactor | 1 | 0 | 0 | DASH_Hsk3 (PF08227, IPR013183): DASH complex subunit Hsk3 like DUF1178 (PF06676, IPR009562): Protein of unknown function (DUF1178) ZapB (PF06005, IPR009252): Cell division protein ZapB JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II |
11 |
CACNA1A | interactor | 1 | 0 | 0 | Ca_chan_IQ (PF08763, IPR014873, SM01062): Voltage gated calcium channel IQ domain GRP (PF07172, IPR010800): Glycine rich protein family Ion_trans (PF00520, IPR005821): Ion transport protein Roughex (PF06020, IPR009259): Drosophila roughex protein SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region GPHH (PF16905, IPR031649): Voltage-dependent L-type calcium channel, IQ-associated |
12 |
CDK19 | interactor | 6 | 0.933 | 0.333 | Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase (PF00069, IPR000719): Protein kinase domain |
13 |
CDK8 | interactor | 9 | 0.750 | 3.000 | Pkinase (PF00069, IPR000719): Protein kinase domain |
14 |
CHD3 | oncoprotein | 11 | 0.644 | 6.577 | CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086) DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087) DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DUF2956 (PF11169, IPR021339): Protein of unknown function (DUF2956) FAM176 (PF14851): FAM176 family |
15 |
CREBBP | oncoprotein | 23 | 0.325 | 110.774 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) |
16 |
CSMD1 | interactor | 1 | 0 | 0 | CUB (PF00431, IPR000859, SM00042): CUB domain Hep_core_N (PF08290, IPR013195): Hepatitis core protein, putative zinc finger Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat) DERM (PF14704): Dermatopontin |
17 |
CTBP1 | protein found in more fusions | 18 | 0.390 | 50.286 | 2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D |
18 |
CTNNB1 | oncoprotein | 12 | 0.470 | 19.492 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat |
19 |
CUL3 | protein found in more fusions | 13 | 0.197 | 49.400 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
20 |
CUTC | interactor | 2 | 0 | 0 | CutC (PF03932, IPR005627): CutC family |
21 |
DDX6 | oncoprotein | 4 | 0.500 | 3.000 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
22 |
DNAH9 | interactor | 1 | 0 | 0 | AAA_5 (PF07728, IPR011704): AAA domain (dynein-related subfamily) DASH_Dad2 (PF08654, IPR013963): DASH complex subunit Dad2 DHC_N1 (PF08385, IPR013594): Dynein heavy chain, N-terminal region 1 DHC_N2 (PF08393, IPR013602): Dynein heavy chain, N-terminal region 2 Dynein_heavy (PF03028, IPR004273): Dynein heavy chain and region D6 of dynein motor Noelin-1 (PF12308, IPR022082): Neurogenesis glycoprotein AAA_6 (PF12774): Hydrolytic ATP binding site of dynein motor region D1 AAA_7 (PF12775): P-loop containing dynein motor region D3 MT (PF12777, IPR024743): Microtubule-binding stalk of dynein motor AAA_8 (PF12780, IPR024317): P-loop containing dynein motor region D4 AAA_9 (PF12781): ATP-binding dynein motor region D5 |
23 |
DROSHA | interactor | 2 | 1.000 | 0 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) Ribonuclease_3 (PF00636, IPR000999, SM00535): Ribonuclease III domain Ribonucleas_3_3 (PF14622, IPR000999): Ribonuclease-III-like DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) |
24 |
E2F3 | oncoprotein | 3 | 1.000 | 0 | E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain |
25 |
EBF1 | oncoprotein | 3 | 1.000 | 0 | TIG (PF01833, IPR002909): IPT/TIG domain COE1_DBD (PF16422, IPR032200): Transcription factor COE1 DNA-binding domain COE1_HLH (PF16423, IPR032201): Transcription factor COE1 helix-loop-helix domain |
26 |
EHMT1 | oncoprotein | 6 | 1.000 | 0 | Pre-SET (PF05033, IPR007728): Pre-SET motif Ribosomal_L32p (PF01783, IPR002677): Ribosomal L32p protein family SET (PF00856, IPR001214, SM00317): SET domain XRCC4 (PF06632, IPR010585): DNA double-strand break repair and V(D)J recombination protein XRCC4 Zip (PF02535, IPR003689): ZIP Zinc transporter Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) DUF4551 (PF15087, IPR027878): Protein of unknown function (DUF4551) |
27 |
EIF2AK3 | interactor | 3 | 0.667 | 1.000 | OATP (PF03137, IPR004156): Organic Anion Transporter Polypeptide (OATP) family Pkinase (PF00069, IPR000719): Protein kinase domain PQQ_2 (PF13360, IPR002372): PQQ-like domain |
28 |
EIF4ENIF1 | interactor | 2 | 1.000 | 0 | EIF4E-T (PF10477, IPR018862): Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF4718 (PF15842, IPR031695): Domain of unknown function (DUF4718) |
29 |
EP300 | oncoprotein | 21 | 0.326 | 79.307 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type |
30 |
EPHB6 | oncoprotein | 2 | 1.000 | 0 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like Phage_holin_5_1 (PF06946, IPR009708): Bacteriophage A118-like holin, Hol118 Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain hEGF (PF12661, IPR013032): Human growth factor-like EGF EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain IMUP (PF15761, IPR026621): Immortalisation up-regulated protein |
31 |
ERCC5 | interactor | 1 | 0 | 0 | 5_3_exonuc (PF01367, IPR020045, SM00475): 5'-3' exonuclease, C-terminal SAM fold XPG_I (PF00867, IPR006086, SM00484): XPG I-region XPG_N (PF00752, IPR006085, SM00485): XPG N-terminal domain IZUMO (PF15005, IPR029389): Izumo sperm-egg fusion, Ig domain-associated Codanin-1_C (PF15296, IPR028171): Codanin-1 C-terminus EF-G-binding_N (PF07299): Elongation factor G-binding protein, N-terminal |
32 |
FBXO11 | oncoprotein | 3 | 1.000 | 0 | TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) F-box-like (PF12937, IPR001810): F-box-like Beta_helix (PF13229): Right handed beta helix region |
33 |
FOXM1 | oncoprotein | 3 | 0.667 | 0.500 | EspF (PF04806, IPR006891): EspF protein repeat Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
34 |
HBEGF | interactor | 2 | 1.000 | 0 | EGF (PF00008, IPR000742, SM00181): EGF-like domain |
35 |
HDAC1 | suppressor | 31 | 0.317 | 167.897 | FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
36 |
HDAC2 | oncoprotein | 22 | 0.419 | 58.235 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1 |
37 |
HDAC4 | oncoprotein | 15 | 0.429 | 25.995 | Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4 |
38 |
HDAC5 | protein found in more fusions | 16 | 0.448 | 33.723 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4 |
39 |
HDAC7 | protein found in more fusions | 11 | 0.733 | 3.004 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 CBP_BcsO (PF17037, IPR031484): Cellulose biosynthesis protein BcsO |
40 |
HDAC9 | interactor | 10 | 0.667 | 3.056 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain SAE2 (PF08573, IPR013882): DNA repair protein endonuclease SAE2/CtIP C-terminus HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4 CEP19 (PF14933, IPR029412): CEP19-like protein |
41 |
HELZ2 | interactor | 1 | 0 | 0 | RNB (PF00773, SM00955): RNB domain zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding AAA_11 (PF13086): AAA domain AAA_12 (PF13087): AAA domain |
42 |
HNF1A | oncoprotein | 5 | 0.667 | 2.000 | HNF-1_N (PF04814, IPR006899): Hepatocyte nuclear factor 1 (HNF-1), N terminus HNF-1A_C (PF04813, IPR006898): Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus HNF-1B_C (PF04812, IPR006897): Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
43 |
HSF4 | interactor | 2 | 1.000 | 0 | Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding |
44 |
HSP90AA1 | oncoprotein | 15 | 0.209 | 64.467 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
45 |
IDI2 | interactor | 1 | 0 | 0 | NUDIX (PF00293, IPR000086): NUDIX domain |
46 |
IL32 | interactor | 4 | 1.000 | 0 | IL32 (PF15225, IPR028067): Interleukin 32 |
47 |
IRF4 | oncoprotein | 2 | 1.000 | 0 | IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3 |
48 |
JUN | oncoprotein | 18 | 0.324 | 60.027 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor |
49 |
JUNB | oncoprotein | 5 | 0.800 | 0.583 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor |
50 |
JUND | oncoprotein | 4 | 0.833 | 0.333 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor |
51 |
KDM2A | interactor | 1 | 0 | 0 | JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain F-box (PF00646, IPR001810, SM00256): F-box domain DZR (PF12773, IPR025874): Double zinc ribbon LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat PHD_4 (PF16866, IPR019787): PHD-finger |
52 |
KIF13B | interactor | 2 | 1.000 | 0 | CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342) FHA (PF00498, IPR000253, SM00240): FHA domain Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain KIF1B (PF12423, IPR022140): Kinesin protein 1B DUF3694 (PF12473, IPR022164): Kinesin protein NCKAP5 (PF15246, IPR032769): Nck-associated protein 5, Peripheral clock protein Kinesin_assoc (PF16183, IPR032405): Kinesin-associated |
53 |
KIFC3 | oncoprotein | 5 | 0.500 | 2.667 | Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein KxDL (PF10241, IPR019371): Uncharacterized conserved protein Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
54 |
KMT2B | oncoprotein | 2 | 1.000 | 0 | FLO_LFY (PF01698, IPR002910): Floricaula / Leafy protein FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus GRP (PF07172, IPR010800): Glycine rich protein family PHD (PF00628, IPR019787, SM00249): PHD-finger SET (PF00856, IPR001214, SM00317): SET domain zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Fer4_2 (PF12797, IPR001450): 4Fe-4S binding domain zf-HC5HC2H (PF13771): PHD-like zinc-binding domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3 |
55 |
LIMS3 | interactor | 1 | 0 | 0 | CagZ (PF09053, IPR015139): CagZ LIM (PF00412, IPR001781, SM00132): LIM domain TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region zf-RRN7 (PF11781, IPR021752): Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-C4pol (PF14260, IPR025687): C4-type zinc-finger of DNA polymerase delta |
56 |
LPAR2 | interactor | 1 | 0 | 0 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srt (PF10321, IPR019425): Serpentine type 7TM GPCR chemoreceptor Srt |
57 |
LPAR4 | interactor | 1 | 0 | 0 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) EVC2_like (PF12297, IPR022076): Ellis van Creveld protein 2 like protein |
58 |
LSM1 | interactor | 2 | 1.000 | 0 | LSM (PF01423, IPR001163): LSM domain |
59 |
MAPK8IP3 | interactor | 2 | 1.000 | 0 | Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion UPF0449 (PF15136, IPR028227): Uncharacterised protein family UPF0449 JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II |
60 |
MBD3 | interactor | 13 | 0.545 | 16.075 | DUF2201_N (PF13203, IPR025154): Putative metallopeptidase domain |
61 |
MED17 | oncoprotein | 8 | 0.679 | 5.067 | Med17 (PF10156, IPR019313): Subunit 17 of Mediator complex |
62 |
MED23 | interactor | 8 | 0.607 | 7.500 | Med23 (PF11573, IPR021629): Mediator complex subunit 23 |
63 |
MED6 | interactor | 6 | 0.933 | 0.333 | Med6 (PF04934, IPR007018): MED6 mediator sub complex component Peptidase_M15 (PF01427, IPR000755): D-ala-D-ala dipeptidase |
64 |
MTA3 | oncoprotein | 7 | 0.857 | 1.150 | BAH (PF01426, IPR001025, SM00439): BAH domain ELM2 (PF01448, IPR000949): ELM2 domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain GATA (PF00320, IPR000679, SM00401): GATA zinc finger |
65 |
NACC1 | interactor | 6 | 0.500 | 2.383 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain BEN (PF10523, IPR018379, SM01025): BEN domain |
66 |
NCOR1 | oncoprotein | 16 | 0.533 | 17.784 | BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp) MAS20 (PF02064, IPR002056): MAS20 protein import receptor Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein Hid1 (PF12722): High-temperature-induced dauer-formation protein Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) RBR (PF17208): RNA binding Region |
67 |
NCOR2 | oncoprotein | 19 | 0.491 | 40.561 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal MAS20 (PF02064, IPR002056): MAS20 protein import receptor OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK) SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Gti1_Pac2 (PF09729, IPR018608): Gti1/Pac2 family PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Spt20 (PF12090, IPR021950): Spt20 family DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4518 (PF15008, IPR026698): Domain of unknown function (DUF4518) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820) |
68 |
NKRF | interactor | 3 | 0.667 | 0.667 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif G-patch (PF01585, IPR000467, SM00443): G-patch domain R3H (PF01424, IPR001374, SM00393): R3H domain XTBD (PF11952, IPR021859): XRN-Two Binding Domain, XTBD |
69 |
OLA1 | interactor | 1 | 0 | 0 | Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase YchF-GTPase_C (PF06071, IPR013029): Protein of unknown function (DUF933) |
70 |
OSBPL1A | interactor | 1 | 0 | 0 | DinB (PF05163, IPR007837): DinB family Oxysterol_BP (PF01237, IPR000648): Oxysterol-binding protein Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) DUF4298 (PF14131, IPR025384): Domain of unknown function (DUF4298) PH_11 (PF15413): Pleckstrin homology domain |
71 |
PANX3 | interactor | 1 | 0 | 0 | Innexin (PF00876, IPR000990): Innexin VirB3 (PF05101, IPR007792): Type IV secretory pathway, VirB3-like protein |
72 |
PARP12 | interactor | 1 | 0 | 0 | PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain WWE (PF02825, IPR004170, SM00678): WWE domain zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger Torus (PF16131, IPR032297): Torus domain |
73 |
PATZ1 | oncoprotein | 4 | 0.667 | 1.000 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger zf-C2H2_assoc3 (PF16637): Putative zinc-finger between two C2H2 zinc-fingers on Patz |
74 |
PCDH9 | interactor | 1 | 0 | 0 | Cadherin_2 (PF08266, IPR013164): Cadherin-like Protocadherin (PF08374, IPR013585): Protocadherin Cadherin (PF00028, IPR002126, SM00112): Cadherin domain Cadherin_3 (PF16184): Cadherin-like |
75 |
PELI1 | interactor | 1 | 0 | 0 | Pellino (PF04710, IPR006800): Pellino |
76 |
PIKFYVE | interactor | 1 | 0 | 0 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger PIP5K (PF01504, IPR002498): Phosphatidylinositol-4-phosphate 5-Kinase |
77 |
PIN1 | suppressor | 11 | 0.400 | 25.965 | Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain WW (PF00397, IPR001202, SM00456): WW domain |
78 |
PLPP3 | oncoprotein | 2 | 0 | 0 | YhhN (PF07947, IPR012506): YhhN-like protein PAP2 (PF01569, IPR000326, SM00014): PAP2 superfamily C1-set_C (PF16196, IPR032431): C1-set C-terminal domain |
79 |
PML | oncoprotein | 20 | 0.421 | 56.686 | zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
80 |
POU2F3 | suppressor | 2 | 1.000 | 0 | Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
81 |
PPARGC1A | interactor | 6 | 0.733 | 1.515 | Pap_E4 (PF02711, IPR003861): E4 protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSRP (PF17069): Arginine/Serine-Rich protein 1 |
82 |
PRKCE | suppressor | 6 | 0.600 | 3.400 | C2 (PF00168, IPR000008, SM00239): C2 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
83 |
PRKD3 | interactor | 2 | 1.000 | 0 | PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
84 |
RAF1 | oncoprotein | 7 | 0.400 | 7.400 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
85 |
RUNX1T1 | oncoprotein | 8 | 0.905 | 0.315 | NHR2 (PF08788, IPR014896): NHR2 domain like TAFH (PF07531, IPR003894, SM00549): NHR1 homology to TAF zf-MYND (PF01753, IPR002893): MYND finger DUF3731 (PF12531, IPR021030): DNA-K related protein |
86 |
SAE1 | interactor | 1 | 0 | 0 | ThiF (PF00899, IPR000594): ThiF family |
87 |
SENP7 | interactor | 1 | 0 | 0 | Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain TMEM215 (PF15746, IPR031486): TMEM215 family |
88 |
SIAH1 | suppressor | 6 | 0.500 | 5.000 | Sina (PF03145, IPR018121): Seven in absentia protein family |
89 |
SIN3A | oncoprotein | 19 | 0.462 | 43.589 | Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein |
90 |
SMARCA4 | oncoprotein | 20 | 0.353 | 89.941 | DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain BRK (PF07533, IPR006576, SM00592): BRK domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065) SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
91 |
SMO | interactor | 1 | 0 | 0 | Frizzled (PF01534, IPR000539): Frizzled/Smoothened family membrane region Fz (PF01392, IPR020067, SM00063): Fz domain |
92 |
SPI1 | oncoprotein | 6 | 0.667 | 4.200 | Ets (PF00178, IPR000418, SM00413): Ets-domain p47_phox_C (PF08944, IPR015039): NADPH oxidase subunit p47Phox, C terminal domain |
93 |
SPTLC2 | interactor | 1 | 0 | 0 | Aminotran_1_2 (PF00155, IPR004839): Aminotransferase class I and II |
94 |
TNFRSF8 | oncoprotein | 3 | 1.000 | 0 | c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain Rib_recp_KP_reg (PF05104, IPR007794): Ribosome receptor lysine/proline rich region TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region |
95 |
TP53 | oncoprotein | 28 | 0.299 | 160.268 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
96 |
TRAF1 | oncoprotein | 8 | 0.333 | 13.167 | HypA (PF01155, IPR000688): Hydrogenase/urease nickel incorporation, metallochaperone, hypA SlyX (PF04102, IPR007236): SlyX TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain |
97 |
TRAF3IP3 | interactor | 1 | 0 | 0 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) FUSC (PF04632, IPR006726): Fusaric acid resistance protein family HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 |
98 |
TRIB3 | interactor | 2 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain |
99 |
TWIST1 | oncoprotein | 6 | 0.800 | 0.956 | ACC_epsilon (PF13822, IPR032716): Acyl-CoA carboxylase epsilon subunit PRR20 (PF15708, IPR031439): Proline-rich protein family 20 FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2 |
100 |
USP7 | oncoprotein | 10 | 0.306 | 16.489 | MATH (PF00917, IPR002083, SM00061): MATH domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal |
101 |
UTP6 | interactor | 1 | 0 | 0 | NRDE-2 (PF08424, IPR013633): NRDE-2, necessary for RNA interference Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1 U3_assoc_6 (PF08640, IPR013949): U3 small nucleolar RNA-associated protein 6 TPR_14 (PF13428): Tetratricopeptide repeat |
102 |
WDR35 | interactor | 2 | 1.000 | 0 | A2L_zn_ribbon (PF08792, IPR014900): A2L zinc ribbon domain Coatomer_WDAD (PF04053, IPR006692): Coatomer WD associated region WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
103 |
WNK4 | interactor | 3 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain OSR1_C (PF12202, IPR024678): Oxidative-stress-responsive kinase 1 C terminal |
104 |
WNT16 | interactor | 1 | 0 | 0 | wnt (PF00110, IPR005817, SM00097): wnt family |
105 |
YY1 | protein found in more fusions | 14 | 0.385 | 32.287 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail |
106 |
ZBTB16 | oncoprotein | 18 | 0.463 | 49.841 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger |
107 |
ZBTB17 | interactor | 5 | 0.833 | 0.500 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain C1_4 (PF07975, IPR004595, SM01047): TFIIH C1-like domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |
108 |
ZBTB7A | interactor | 10 | 0.667 | 4.402 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain GAGA (PF09237, IPR015318): GAGA factor zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |
109 |
ZBTB7B | interactor | 6 | 0.600 | 1.639 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal GAGA (PF09237, IPR015318): GAGA factor SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
110 |
ZMYND8 | oncoprotein | 8 | 0.643 | 5.283 | DUF1640 (PF07798, IPR024461): Protein of unknown function (DUF1640) Mucin (PF01456, IPR000458): Mucin-like glycoprotein PHD (PF00628, IPR019787, SM00249): PHD-finger PWWP (PF00855, IPR000313, SM00293): PWWP domain RNA_pol_Rbc25 (PF08292, IPR013238): RNA polymerase III subunit Rpc25 TCP (PF03634, IPR005333): TCP family transcription factor zf-MYND (PF01753, IPR002893): MYND finger Bromodomain (PF00439, IPR001487, SM00297): Bromodomain DUF3544 (PF12064, IPR021931): Domain of unknown function (DUF3544) CAML (PF14963, IPR016719): Calcium signal-modulating cyclophilin ligand |
111 |
ZNF443 | interactor | 1 | 0 | 0 | KRAB (PF01352, IPR001909, SM00349): KRAB box zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger YhfH (PF14149, IPR025432): YhfH-like protein |