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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins BCAT2 (from a repository: Tue Jul 16 05:31:57 2019)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)10
The number (and %) of the onco-proteins2 (20.00 %)
The number (and %) of the tumor suppressors1 (10.00 %)
Total number of binary PPIs (saturation %)17 (37.78 %)
The number (and %) of affected PPIs10 (58.82 %)
The number of possible different fusions4
PPI diameter2
PPI radius1
The average degree of PPI2.200
Assortativity coefficient-0.3269
The network average Clustering coefficient0.272
The number (and %) of a zero Clustering coefficients6 (60.00 %)
The number (and %) of a zero Betweenness Centrality8 (80.00 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: BCAT2 All fusions
Proteins found in more fusions APP (see 5 fusions); BCAT2 (see 1 fusions); ALDOA (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 BCAT2parental protein100.05667.000Aminotran_4 (PF01063, IPR001544): Amino-transferase class IV
2 ALDOAprotein found in more fusions200Glycolytic (PF00274, IPR000741): Fructose-bisphosphate aldolase class-I
3 APPprotein found in more fusions40.6671.000APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
4 C11orf54interactor21.0000DUF1907 (PF08925, IPR015021, SM01168): Domain of Unknown Function (DUF1907)
5 CATsuppressor31.0000Catalase (PF00199, IPR011614, SM01060): Catalase
Catalase-rel (PF06628, IPR010582): Catalase-related immune-responsive
6 CREB3interactor200bZIP_1 (PF00170, IPR004827): bZIP transcription factor
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
7 EEF2KMTinteractor100Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase
FAM86 (PF14904, IPR029426): Family of unknown function
8 ETFAinteractor100ETF (PF01012, IPR014730, SM00893): Electron transfer flavoprotein domain
ETF_alpha (PF00766, IPR014731): Electron transfer flavoprotein FAD-binding domain
9 PTGDSinteractor200Lipocalin (PF00061, IPR000566): Lipocalin / cytosolic fatty-acid binding protein family
10 UFM1interactor100Ufm1 (PF03671, IPR005375): Ubiquitin fold modifier 1 protein

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