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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins BATF3 (from a repository: Mon Dec 5 09:01:52 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)21
The number (and %) of the onco-proteins9 (42.86 %)
The number (and %) of the tumor suppressors5 (23.81 %)
Total number of binary PPIs (saturation %)95 (45.24 %)
The number (and %) of affected PPIs21 (22.11 %)
The number of possible different fusions5
PPI diameter2
PPI radius1
The average degree of PPI7.524
Assortativity coefficient-0.2894
The network average Clustering coefficient0.734
The number (and %) of a zero Clustering coefficients2 (9.52 %)
The number (and %) of a zero Betweenness Centrality6 (28.57 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: BATF3 All fusions
Proteins found in more fusions STAT3 (see 2 fusions); EPAS1 (see 1 fusions); ATF2/DDIT3 (see 1 fusions); BATF3 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 BATF3parental protein210.311166.658bZIP_1 (PF00170, IPR004827): bZIP transcription factor
2 APPL1interactor200ATP-synt_E (PF05680, IPR008386): ATP synthase E chain
Fzo_mitofusin (PF04799, IPR006884): fzo-like conserved region
PH (PF00169, IPR001849, SM00233): PH domain
PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
BAR_3 (PF16746): BAR domain of APPL family
3 ATF2oncoprotein90.9640.222bZIP_1 (PF00170, IPR004827): bZIP transcription factor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
4 ATF3suppressor160.48638.691bZIP_1 (PF00170, IPR004827): bZIP transcription factor
5 ATF4oncoprotein110.8442.572bZIP_1 (PF00170, IPR004827): bZIP transcription factor
6 BACH2oncoprotein41.0000BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor
7 BATFoncoprotein130.7127.825bZIP_1 (PF00170, IPR004827): bZIP transcription factor
8 CEBPAsuppressor100.8611.536Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
DUF2514 (PF10721, IPR019659): Protein of unknown function (DUF2514)
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
9 CEBPEinteractor90.9640.222Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
10 CEBPGinteractor110.8671.758bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89
11 CRKoncoprotein21.0000SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
12 DBPinteractor70.8101.522bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
13 DDIT3oncoprotein150.51628.769IFP_35_N (PF07334, IPR009938): Interferon-induced 35 kDa protein (IFP 35) N-terminus
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
14 EPAS1suppressor60.9000.286Corona_I (PF03187, IPR004876): Corona nucleocapsid I protein
HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
PAS (PF00989, IPR013767, SM00091): PAS fold
HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
PAS_11 (PF14598): PAS domain
15 JUNoncoprotein120.7098.939bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
16 JUNBoncoprotein51.0000bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
17 MAFFinteractor60.9000.500bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor
APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
18 MAFGoncoprotein60.9000.500bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor
ThrE_2 (PF12821, IPR024528): Threonine/Serine exporter, ThrE
19 NFATC2IPinteractor100Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
20 PGRsuppressor31.0000Prog_receptor (PF02161, IPR000128): Progesterone receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
21 STAT3suppressor50.6672.000SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain

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