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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins ATG2B (from a repository: Thu Nov 10 14:59:26 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)12
The number (and %) of the onco-proteins1 (8.33 %)
The number (and %) of the tumor suppressors1 (8.33 %)
Total number of binary PPIs (saturation %)19 (28.79 %)
The number (and %) of affected PPIs11 (57.89 %)
The number of possible different fusions0
PPI diameter2
PPI radius1
The average degree of PPI3.000
Assortativity coefficient-0.7053
The network average Clustering coefficient0.566
The number (and %) of a zero Clustering coefficients3 (25.00 %)
The number (and %) of a zero Betweenness Centrality8 (66.67 %)

ACTIVE INTERACTORS


List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 ATG2Bparental protein110.12784.000ATG_C (PF09333, IPR015412): Autophagy-related protein C terminal domain
Chorein_N (PF12624, IPR026854): N-terminal region of Chorein or VPS13
ATG2_CAD (PF13329, IPR026885): Autophagy-related protein 2 CAD motif
VPS13 (PF16908, IPR031646): Vacuolar sorting-associated protein 13, N-terminal
VPS13_C (PF16909, IPR031645): Vacuolar-sorting-associated 13 protein C-terminal
2 ATG2Ainteractor21.0000ATG_C (PF09333, IPR015412): Autophagy-related protein C terminal domain
Chorein_N (PF12624, IPR026854): N-terminal region of Chorein or VPS13
ATG2_CAD (PF13329, IPR026885): Autophagy-related protein 2 CAD motif
VPS13_C (PF16909, IPR031645): Vacuolar-sorting-associated 13 protein C-terminal
3 CEP89interactor30.6671.000ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CorA (PF01544, IPR002523): CorA-like Mg2+ transporter protein
Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit
Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain
Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
4 HDAC11interactor100Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
5 LHX6suppressor21.0000BON (PF04972, IPR007055, SM00749): BON domain
LIM (PF00412, IPR001781, SM00132): LIM domain
zf-dskA_traR (PF01258, IPR000962): Prokaryotic dksA/traR C4-type zinc finger
DUF2175 (PF09943, IPR018686): Uncharacterized protein conserved in archaea (DUF2175)
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
6 MED4interactor21.0000Med4 (PF10018, IPR019258): Vitamin-D-receptor interacting Mediator subunit 4
7 MLF1interactor100Mlf1IP (PF10248, IPR019376): Myelodysplasia-myeloid leukemia factor 1-interacting protein
8 NTRK1oncoprotein31.0000I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
9 POC1Ainteractor21.0000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
10 TALDO1interactor30.6671.000TAL_FSA (PF00923, IPR001585): Transaldolase/Fructose-6-phosphate aldolase
11 WDR45interactor60.33310.000CNH (PF00780, IPR001180, SM00036): CNH domain
DUF1736 (PF08409, IPR013618): Domain of unknown function (DUF1736)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
12 ZSCAN26interactor100C1_4 (PF07975, IPR004595, SM01047): TFIIH C1-like domain
SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain

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