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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)252
The number (and %) of the onco-proteins81 (32.14 %)
The number (and %) of the tumor suppressors46 (18.25 %)
Total number of binary PPIs (saturation %)1599 (5.06 %)
The number (and %) of affected PPIs271 (16.95 %)
The number of possible different fusions48
PPI diameter3
PPI radius2
The average degree of PPI11.897
Assortativity coefficient-0.1853
The network average Clustering coefficient0.403
The number (and %) of a zero Clustering coefficients31 (12.30 %)
The number (and %) of a zero Betweenness Centrality43 (17.06 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: ATF2,DDIT3 All fusions
: BU662818;
Proteins found in more fusions SMAD4 (see 2 fusions); MAPK1 (see 1 fusions); ZDHHC17 (see 2 fusions); CUL1 (see 3 fusions); CUL3 (see 1 fusions); AHNAK (see 2 fusions); MAPK9 (see 3 fusions); CDK6 (see 1 fusions); BCAP31 (see 3 fusions); ARF1 (see 2 fusions); MDH2 (see 1 fusions); TFRC (see 1 fusions); IMMT (see 4 fusions); CTTN (see 1 fusions); AMOTL2 (see 1 fusions); HDAC5 (see 1 fusions); EP300 (see 1 fusions); PCNA (see 1 fusions); CCND1 (see 1 fusions); SS18 (see 1 fusions); RTN4 (see 11 fusions); APP (see 4 fusions); TPM1 (see 2 fusions); YWHAG (see 1 fusions); ATP1A1/VDAC3 (see 2 fusions); HSP90AA1 (see 2 fusions); ACTN1 (see 3 fusions); HDAC4 (see 1 fusions); NCOA6 (see 1 fusions); CREB1 (see 2 fusions); YY1 (see 2 fusions); MAPK14 (see 1 fusions); CALR (see 6 fusions); CREBBP (see 6 fusions); ATF2/DDIT3 (see 1 fusions); BATF3 (see 1 fusions); HSPB1 (see 4 fusions); KAT5 (see 3 fusions); FOS (see 4 fusions); CSNK2A1 (see 1 fusions); EPAS1 (see 1 fusions); PML (see 4 fusions); PRKCE (see 3 fusions); SMAD3 (see 3 fusions); GAPDH (see 2 fusions); ATP1A1/MAPK1 (see 1 fusions); ACADVL (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 ATF2parental protein2020.04638498.755bZIP_1 (PF00170, IPR004827): bZIP transcription factor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
2 DDIT3parental protein700.08111021.979IFP_35_N (PF07334, IPR009938): Interferon-induced 35 kDa protein (IFP 35) N-terminus
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
3 ACADVLprotein found in more fusions200Acyl-CoA_dh_1 (PF00441, IPR009075): Acyl-CoA dehydrogenase, C-terminal domain
Acyl-CoA_dh_M (PF02770, IPR006091): Acyl-CoA dehydrogenase, middle domain
Acyl-CoA_dh_N (PF02771, IPR013786): Acyl-CoA dehydrogenase, N-terminal domain
4 ACTN1protein found in more fusions120.200160.184CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Dak2 (PF02734, IPR004007, SM01120): DAK2 domain
EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
Uds1 (PF15456, IPR029191): Up-regulated During Septation
5 AHCYinteractor100.27825.605AdoHcyase (PF05221, IPR000043, SM00996): S-adenosyl-L-homocysteine hydrolase
AdoHcyase_NAD (PF00670, IPR015878, SM00997): S-adenosyl-L-homocysteine hydrolase, NAD binding domain
6 AHNAKsuppressor90.46413.534DUF945 (PF06097, IPR010352): Bacterial protein of unknown function (DUF945)
ELFV_dehydrog_N (PF02812, IPR006097): Glu/Leu/Phe/Val dehydrogenase, dimerisation domain
T2SSN (PF01203, IPR022792): Type II secretion system (T2SS), protein N
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
TT_ORF2a (PF08197, IPR013267): pORF2a truncated protein
DUF2993 (PF11209, IPR021373): Protein of unknown function (DUF2993)
DUF4097 (PF13349, IPR025164): Putative adhesin
Ntox37 (PF15535, IPR029108): Bacterial toxin 37
7 AHSGinteractor100Cystatin (PF00031, IPR000010, SM00043): Cystatin domain
8 ALDOAinteractor180.41952.309Glycolytic (PF00274, IPR000741): Fructose-bisphosphate aldolase class-I
9 AMOTL2protein found in more fusions31.0000HOOK (PF05622, IPR008636): HOOK protein
SlyX (PF04102, IPR007236): SlyX
Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
10 ANXA1suppressor110.26746.489Annexin (PF00191, IPR018502, SM00335): Annexin
11 ANXA3interactor100Annexin (PF00191, IPR018502, SM00335): Annexin
RPT (PF13446, IPR025305): A repeated domain in UCH-protein
12 ANXA5oncoprotein60.4675.488Annexin (PF00191, IPR018502, SM00335): Annexin
13 APMAPinteractor30.6670.880Str_synth (PF03088, IPR018119): Strictosidine synthase
14 APPprotein found in more fusions540.1101585.392APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
15 ARF1suppressor80.5717.256Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
16 ARF4interactor80.53611.333Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
17 ATF1oncoprotein100.44422.594bZIP_1 (PF00170, IPR004827): bZIP transcription factor
pKID (PF02173, IPR003102): pKID domain
DUF4988 (PF16378, IPR032149): Domain of unknown function
18 ATF3suppressor310.347438.318bZIP_1 (PF00170, IPR004827): bZIP transcription factor
19 ATF4oncoprotein220.467218.756bZIP_1 (PF00170, IPR004827): bZIP transcription factor
20 ATMsuppressor140.282127.021FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
HEAT (PF02985, IPR000357): HEAT repeat
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair
ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
21 ATP1A1protein found in more fusions160.45058.760Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus
Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus
E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
Tetraspannin (PF00335, IPR018499): Tetraspanin family
Cation_ATPase (PF13246): Cation transport ATPase (P-type)
22 ATP2A2interactor60.3339.783Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus
Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus
E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
HAD (PF12710): haloacid dehalogenase-like hydrolase
Cation_ATPase (PF13246): Cation transport ATPase (P-type)
23 ATP2A3interactor100Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus
Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus
E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
HAD (PF12710): haloacid dehalogenase-like hydrolase
Cation_ATPase (PF13246): Cation transport ATPase (P-type)
24 ATP5Binteractor200.274229.536AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
NACHT (PF05729): NACHT domain
25 ATP5Ointeractor110.49121.879OSCP (PF00213, IPR000711): ATP synthase delta (OSCP) subunit
26 ATPAF2interactor3012.896ATP12 (PF07542, IPR011419): ATP12 chaperone protein
Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14
27 BACH1interactor130.242195.626BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor
Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89
28 BACH2oncoprotein50.7003.018BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor
29 BASP1suppressor30.6670.444BASP1 (PF05466, IPR008408): Brain acid soluble protein 1 (BASP1 protein)
30 BATFoncoprotein150.538289.637bZIP_1 (PF00170, IPR004827): bZIP transcription factor
31 BATF2suppressor100.51113.424bZIP_1 (PF00170, IPR004827): bZIP transcription factor
PRIMA1 (PF16101): Proline-rich membrane anchor 1
32 BATF3protein found in more fusions160.524241.263bZIP_1 (PF00170, IPR004827): bZIP transcription factor
33 BCAP31protein found in more fusions100.50012.650Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
34 BSGinteractor40.6672.232Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
35 C14orf80interactor100DUF4509 (PF14970, IPR027996): Domain of unknown function (DUF4509)
DUF4510 (PF14971, IPR028100): Domain of unknown function (DUF4510)
36 CALRoncoprotein160.35245.502Calreticulin (PF00262, IPR001580): Calreticulin family
DDHD (PF02862, IPR004177, SM01127): DDHD domain
37 CALUinteractor70.6194.425EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
38 CANXinteractor210.276159.420Calreticulin (PF00262, IPR001580): Calreticulin family
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
39 CAP1interactor60.4005.373CAP_C (PF08603, IPR013912): Adenylate cyclase associated (CAP) C terminal
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
40 CCDC153interactor100DUF722 (PF05263, IPR007927): Protein of unknown function (DUF722)
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein
41 CCDC6oncoprotein80.25049.644CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DUF2046 (PF09755, IPR019152): Uncharacterized conserved protein H4 (DUF2046)
FAM199X (PF15814, IPR029672): Protein family FAM199X
42 CCND1oncoprotein110.33361.293Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
43 CCT2interactor170.45651.789Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
44 CCT3interactor180.43164.145Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
45 CCT4interactor140.50527.548Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
46 CCT5interactor140.40749.696Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
47 CD44suppressor40.6672.390VP4_2 (PF08935, IPR015031): Viral protein VP4 subunit
Xlink (PF00193, IPR000538, SM00445): Extracellular link domain
S36_mt (PF10937, IPR020373): Ribosomal protein S36, mitochondrial
48 CDK6suppressor70.20028.075Pkinase (PF00069, IPR000719): Protein kinase domain
49 CEBPAsuppressor230.398198.939Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
DUF2514 (PF10721, IPR019659): Protein of unknown function (DUF2514)
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
50 CEBPBoncoprotein160.58147.042RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
51 CEBPEinteractor160.52448.272Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
52 CEBPGinteractor160.648138.329bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89
53 CFL1interactor220.255135.684Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
54 CLIC1interactor2013.572GST_N_2 (PF13409, IPR004045): Glutathione S-transferase, N-terminal domain
GST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain
55 COLGALT1interactor30.6670.583Glyco_transf_25 (PF01755, IPR002654): Glycosyltransferase family 25 (LPS biosynthesis protein)
Glyco_tranf_2_4 (PF13704): Glycosyl transferase family 2
56 COPS3interactor100.51131.888RasGEF (PF00617, IPR001895, SM00147): RasGEF domain
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
PCI (PF01399, IPR000717, SM00088): PCI domain
57 COPS7Ainteractor70.61916.052PCI (PF01399, IPR000717, SM00088): PCI domain
58 COPS8interactor80.71414.454CSN8_PSD8_EIF3K (PF10075): CSN8/PSMD8/EIF3K family
59 CREB1oncoprotein240.316213.701bZIP_1 (PF00170, IPR004827): bZIP transcription factor
pKID (PF02173, IPR003102): pKID domain
DUF4988 (PF16378, IPR032149): Domain of unknown function
60 CREB3interactor90.46432.541bZIP_1 (PF00170, IPR004827): bZIP transcription factor
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
61 CREB3L1suppressor31.0000bZIP_1 (PF00170, IPR004827): bZIP transcription factor
ELP6 (PF09807, IPR018627): Elongation complex protein 6
62 CREB5interactor90.42922.777bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Zip (PF02535, IPR003689): ZIP Zinc transporter
Shisa (PF13908, IPR026910): Wnt and FGF inhibitory regulator
63 CREBBPsuppressor330.319343.725Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
64 CSinteractor50.5003.184Citrate_synt (PF00285, IPR002020): Citrate synthase, C-terminal domain
65 CSNK2A1oncoprotein250.250399.122Pkinase (PF00069, IPR000719): Protein kinase domain
66 CTNNB1oncoprotein260.222395.819Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
67 CTNND1suppressor50.8001.377Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Ebp2 (PF05890, IPR008610): Eukaryotic rRNA processing protein EBP2
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
68 CTTNoncoprotein100.30665.302FadA (PF09403, IPR018543): Adhesion protein FadA
HS1_rep (PF02218, IPR003134): Repeat in HS1/Cortactin
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
69 CUL1suppressor310.172469.083Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
70 CUL3protein found in more fusions590.1322402.652Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
71 CYC1interactor110.60012.803Cytochrom_C1 (PF02167, IPR002326): Cytochrome C1 family
72 DBPinteractor80.7504.637bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
73 DDOSTinteractor150.50536.564DDOST_48kD (PF03345, IPR005013): Oligosaccharyltransferase 48 kDa subunit beta
74 DDX39Binteractor90.41716.334DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
75 DGCR2interactor100UL45 (PF05473, IPR008646): UL45 protein, carbohydrate-binding C-type lectin-like
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A
76 DLDinteractor70.33317.170Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
Pyr_redox_dim (PF02852, IPR004099): Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
77 DNMT3Linteractor180.412254.269CEBP_ZZ (PF16366, IPR032296): Cytoplasmic polyadenylation element-binding protein ZZ domain
78 EEF2interactor160.31785.519EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus
EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
EFG_II (PF14492, IPR009022): Elongation Factor G, domain II
79 EIF5Ainteractor50.4005.381EFP_N (PF08207, IPR013185): Elongation factor P (EF-P) KOW-like domain
eIF-5a (PF01287, IPR020189): Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
80 EMSYoncoprotein21.0000ENT (PF03735, IPR005491): ENT domain
PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1
GTA_TIM (PF13547, IPR025195): GTA TIM-barrel-like domain
IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
81 ENO1oncoprotein200.332126.700Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain
Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
82 EP300oncoprotein450.211861.420Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
83 EPAS1suppressor150.330111.131Corona_I (PF03187, IPR004876): Corona nucleocapsid I protein
HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
PAS (PF00989, IPR013767, SM00091): PAS fold
HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
PAS_11 (PF14598): PAS domain
84 ERO1Ainteractor50.9000.333ERO1 (PF04137, IPR007266): Endoplasmic Reticulum Oxidoreductin 1 (ERO1)
85 ERP29interactor30.6670.333ERp29 (PF07749, IPR011679): Endoplasmic reticulum protein ERp29, C-terminal domain
ERp29_N (PF07912, IPR012883): ERp29, N-terminal domain
86 ETS1oncoprotein120.51526.720Ets (PF00178, IPR000418, SM00413): Ets-domain
SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
87 EXOSC8interactor200RNase_PH (PF01138, IPR001247): 3' exoribonuclease family, domain 1
RNase_PH_C (PF03725, IPR015847): 3' exoribonuclease family, domain 2
88 F2interactor100Gla (PF00594, IPR000294, SM00069): Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain
Kringle (PF00051, IPR000001): Kringle domain
Thrombin_light (PF09396, IPR018992): Thrombin light chain
Trypsin (PF00089, IPR001254, SM00020): Trypsin
Antifungal_pept (PF11410, IPR024206): Antifungal peptide
89 FHsuppressor90.5009.999Lyase_1 (PF00206, IPR022761): Lyase
FumaraseC_C (PF10415, IPR018951): Fumarase C C-terminus
90 FOSoncoprotein290.336315.101bZIP_1 (PF00170, IPR004827): bZIP transcription factor
91 FOSL1oncoprotein140.61550.976bZIP_1 (PF00170, IPR004827): bZIP transcription factor
92 FOSL2oncoprotein120.394180.044bZIP_1 (PF00170, IPR004827): bZIP transcription factor
93 FSCN1oncoprotein31.0000Fascin (PF06268, IPR022768): Fascin domain
94 FUBP1oncoprotein100.31131.828DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897)
KH_1 (PF00013, IPR004088, SM00322): KH domain
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
95 GANABsuppressor100.53315.759Glyco_hydro_31 (PF01055, IPR000322): Glycosyl hydrolases family 31
Gal_mutarotas_2 (PF13802, IPR025887): Galactose mutarotase-like
DUF5110 (PF17137): Domain of unknown function (DUF5110)
96 GAPDHoncoprotein220.352121.541Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
OstA (PF03968, IPR005653): OstA-like protein
97 GIPC1interactor3040.387PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
98 GLSinteractor21.0000Glutaminase (PF04960, IPR015868): Glutaminase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
99 GLUD2interactor21.0000ELFV_dehydrog (PF00208, IPR006096, SM00839): Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
ELFV_dehydrog_N (PF02812, IPR006097): Glu/Leu/Phe/Val dehydrogenase, dimerisation domain
SF3b10 (PF07189, IPR009846): Splicing factor 3B subunit 10 (SF3b10)
100 GNB2interactor40.3335.375WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
CALM_bind (PF16025): Calcium-dependent calmodulin binding
WD40_like (PF17005, IPR031544): WD40-like domain
101 GP1BAinteractor100LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
102 GRPEL1interactor90.39313.889GrpE (PF01025, IPR000740): GrpE
103 GSTP1suppressor60.4004.955GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain
GST_C_3 (PF14497, IPR004046): Glutathione S-transferase, C-terminal domain
104 H2AFXsuppressor260.191226.588Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
105 H2AFYinteractor40.5002.304DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Macro (PF01661, IPR002589, SM00506): Macro domain
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
106 HADHAinteractor40.3333.9363HCDH (PF00725, IPR006108): 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
3HCDH_N (PF02737, IPR006176): 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase
107 HADHBinteractor50.7002.000Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain
Thiolase_N (PF00108, IPR020616): Thiolase, N-terminal domain
108 HDAC1suppressor500.1551174.489FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
109 HDAC4oncoprotein160.37141.104Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
110 HDAC5protein found in more fusions540.1101713.083Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NOA36 (PF06524, IPR010531): NOA36 protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
111 HDAC6oncoprotein240.126302.202Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
PSGP (PF07276, IPR009900): Apopolysialoglycoprotein (PSGP)
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
112 HK1interactor50.4004.052Hexokinase_1 (PF00349, IPR022672): Hexokinase
Hexokinase_2 (PF03727, IPR022673): Hexokinase
113 HMGA1oncoprotein130.50025.483AT_hook (PF02178, IPR017956, SM00384): AT hook motif
DUF2239 (PF09998, IPR018715): Uncharacterized protein conserved in bacteria (DUF2239)
114 HNRNPH1oncoprotein130.34657.676RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
115 HOXA5interactor30.6670.333Chorion_2 (PF03964, IPR005649): Chorion family 2
Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
Terminase_5 (PF06056, IPR010332): Putative ATPase subunit of terminase (gpP-like)
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
116 HSD17B14interactor200adh_short_C2 (PF13561): Enoyl-(Acyl carrier protein) reductase
117 HSP90AA1oncoprotein440.1611154.915HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
118 HSP90B1suppressor220.299166.348CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT
HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region
119 HSPB1oncoprotein200.193142.150HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
120 HSPD1suppressor180.242121.731Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
121 HSPE1interactor160.27595.072Cpn10 (PF00166, IPR020818, SM00883): Chaperonin 10 Kd subunit
122 HSPH1oncoprotein90.55614.079HSP70 (PF00012, IPR013126): Hsp70 protein
SICA_alpha (PF12887, IPR024290): SICA extracellular alpha domain
123 IKBKGinteractor140.167192.482CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725)
NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO
LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
124 IMMTprotein found in more fusions120.34546.520Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
125 IRF2BP1interactor30.6670.685zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
IRF-2BP1_2 (PF11261, IPR022750): Interferon regulatory factor 2-binding protein zinc finger
126 ITGA2interactor31.0000FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain
VCBS (PF13517): Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
FG-GAP_2 (PF14312, IPR013517): FG-GAP repeat
127 ITGB1suppressor90.33321.804EGF_2 (PF07974, IPR013111): EGF-like domain
Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain
Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain
Integrin_beta (PF00362, IPR002369, SM00187): Integrin, beta chain
PSI_integrin (PF17205): Integrin plexin domain
128 ITGB4oncoprotein21.0000Calx-beta (PF03160, IPR003644, SM00237): Calx-beta domain
EGF_2 (PF07974, IPR013111): EGF-like domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain
SEA (PF01390, IPR000082, SM00200): SEA domain
STOP (PF05217, IPR024963): STOP protein
Integrin_beta (PF00362, IPR002369, SM00187): Integrin, beta chain
PSI_integrin (PF17205): Integrin plexin domain
129 JDP2suppressor90.25035.114bZIP_1 (PF00170, IPR004827): bZIP transcription factor
130 JUNoncoprotein470.262863.976bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
131 JUNBoncoprotein180.37384.453bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
132 JUNDoncoprotein170.301151.243bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
133 KAT5suppressor270.283240.767MOZ_SAS (PF01853, IPR002717): MOZ/SAS family
Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
134 KEAP1oncoprotein60.50024.661BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
135 KIFC3oncoprotein50.5003.010Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
136 KPNA2interactor140.187158.756Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
IBB (PF01749, IPR002652): Importin beta binding domain
Arm_3 (PF16186, IPR032413): Atypical Arm repeat
137 KRT18interactor90.35734.248Filament (PF00038, IPR001664): Intermediate filament protein
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
138 KRT7interactor21.0000Filament (PF00038, IPR001664): Intermediate filament protein
Keratin_2_head (PF16208, IPR032444): Keratin type II head
139 KRT8interactor90.36139.515Filament (PF00038, IPR001664): Intermediate filament protein
Keratin_2_head (PF16208, IPR032444): Keratin type II head
140 LDHAinteractor210.33798.383Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
141 LDHBinteractor190.34066.392Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
142 LDOC1Linteractor21.0000ZapB (PF06005, IPR009252): Cell division protein ZapB
DUF4939 (PF16297, IPR032549): Domain of unknown function (DUF4939)
143 LLGL2interactor200Lgl_C (PF08596, IPR013905): Lethal giant larvae(Lgl) like, C-terminal
LLGL (PF08366, IPR013577): LLGL2
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
RAB3GAP2_N (PF14655, IPR032839): Rab3 GTPase-activating protein regulatory subunit N-terminus
144 LMO2oncoprotein50.16730.458CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
LIM (PF00412, IPR001781, SM00132): LIM domain
145 MAFFinteractor130.288115.089bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor
APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
146 MAFGoncoprotein100.38952.345bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor
ThrE_2 (PF12821, IPR024528): Threonine/Serine exporter, ThrE
147 MAPK1oncoprotein230.290144.442Pkinase (PF00069, IPR000719): Protein kinase domain
148 MAPK10suppressor90.46410.656Pkinase (PF00069, IPR000719): Protein kinase domain
149 MAPK11interactor70.4767.677HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Pkinase (PF00069, IPR000719): Protein kinase domain
150 MAPK13oncoprotein30.6670.544Pkinase (PF00069, IPR000719): Protein kinase domain
151 MAPK14oncoprotein180.331254.081Pkinase (PF00069, IPR000719): Protein kinase domain
152 MAPK3oncoprotein130.37938.836Pkinase (PF00069, IPR000719): Protein kinase domain
153 MAPK8oncoprotein210.300152.026DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530)
Pkinase (PF00069, IPR000719): Protein kinase domain
154 MAPK9suppressor110.400178.703Pkinase (PF00069, IPR000719): Protein kinase domain
Kinase-like (PF14531, IPR027916): Kinase-like
155 MARCKSsuppressor21.0000MARCKS (PF02063, IPR002101): MARCKS family
156 MCMBPinteractor31.0000MCM_bind (PF09739, IPR019140): Mini-chromosome maintenance replisome factor
157 MDH2protein found in more fusions90.32116.741Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
158 MLH1suppressor120.25843.982DNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain
HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Mlh1_C (PF16413, IPR032189): DNA mismatch repair protein Mlh1 C-terminus
159 MRE11Aoncoprotein90.6794.194APG6 (PF04111, IPR007243): Autophagy protein Apg6
Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
Mre11_DNA_bind (PF04152, IPR007281): Mre11 DNA-binding presumed domain
160 MYDGFinteractor100UPF0556 (PF10572, IPR018887): Uncharacterised protein family UPF0556
161 NACAoncoprotein50.5002.335NAC (PF01849, IPR002715): NAC domain
RNA_pol_Rpo13 (PF12136, IPR021985): RNA polymerase Rpo13 subunit HTH domain
CitT (PF12431, IPR028141): Transcriptional regulator
162 NBNsuppressor80.6794.194FHA (PF00498, IPR000253, SM00240): FHA domain
Nbs1_C (PF08599, IPR013908): DNA damage repair protein Nbs1
NIBRIN_BRCT_II (PF16508, IPR032429): Second BRCT domain on Nijmegen syndrome breakage protein
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
163 NCOA6oncoprotein100.6948.584DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719)
Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1
Presenilin (PF01080, IPR001108): Presenilin
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
Nucleic_acid_bd (PF13820, IPR032715): Putative nucleic acid-binding region
NST1 (PF13945, IPR025279): Salt tolerance down-regulator
164 NFATC1oncoprotein140.50533.694RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
165 NFIL3interactor80.33321.263Vert_IL3-reg_TF (PF06529, IPR010533): Vertebrate interleukin-3 regulated transcription factor
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
166 NFYAinteractor100.51123.158CBFB_NFYA (PF02045, IPR001289): CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B
MSP1_C (PF07462, IPR010901): Merozoite surface protein 1 (MSP1) C-terminus
FixG_C (PF11614, IPR032879): IG-like fold at C-terminal of FixG, putative oxidoreductase
DUF4237 (PF14021, IPR025331): Protein of unknown function (DUF4237)
167 NME2P1interactor21.0000NA
168 OATinteractor201.317Aminotran_3 (PF00202, IPR005814): Aminotransferase class-III
169 P4HBinteractor220.305149.705Glycos_trans_3N (PF02885, IPR017459): Glycosyl transferase family, helical bundle domain
Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
170 PCBP1oncoprotein100.46722.068Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein
KH_2 (PF07650, IPR004044): KH domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
171 PCNAoncoprotein260.270226.525PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain
PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain
172 PDIA3interactor170.243121.226Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
173 PDIA4interactor50.9000.333Calsequestrin (PF01216, IPR001393): Calsequestrin
Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
FAM176 (PF14851): FAM176 family
174 PFN1suppressor50.4006.154Profilin (PF00235, IPR005455, SM00392): Profilin
175 PHBsuppressor240.301206.331Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
DUF4290 (PF14123, IPR025632): Domain of unknown function (DUF4290)
176 PHB2interactor180.327110.712DUF2605 (PF10792, IPR019728): Protein of unknown function (DUF2605)
Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
177 PKMoncoprotein240.286154.174PK (PF00224, IPR015793): Pyruvate kinase, barrel domain
PK_C (PF02887, IPR015795): Pyruvate kinase, alpha/beta domain
178 PMLsuppressor230.320159.714zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
179 POLR1Dinteractor100RNA_pol_L_2 (PF13656): RNA polymerase Rpb3/Rpb11 dimerisation domain
180 PPIBinteractor90.167107.622Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
181 PPIFinteractor40.5003.200Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
182 PRDX5interactor80.4648.255Redoxin (PF08534, IPR013740): Redoxin
NAD_binding_10 (PF13460, IPR016040): NAD(P)H-binding
183 PRKCEsuppressor100.38976.165C2 (PF00168, IPR000008, SM00239): C2 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
184 PTPN1suppressor50.6001.616Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
185 RAB11Aoncoprotein70.6195.708Ras (PF00071, IPR001806, SM00173): Ras family
186 RAB14oncoprotein21.0000Ras (PF00071, IPR001806, SM00173): Ras family
187 RAB2Aoncoprotein110.50915.810Ras (PF00071, IPR001806, SM00173): Ras family
188 RAB2Boncoprotein21.0000PNK3P (PF08645, IPR013954): Polynucleotide kinase 3 phosphatase
Ras (PF00071, IPR001806, SM00173): Ras family
189 RAB7Asuppressor140.31946.878Ras (PF00071, IPR001806, SM00173): Ras family
190 RAI1interactor208.404Lin-8 (PF03353, IPR005020): Ras-mediated vulval-induction antagonist
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
191 RB1suppressor190.363189.889RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain
RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain
Rb_C (PF08934, IPR015030): Rb C-terminal domain
DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592)
192 RHOConcoprotein21.0000Ras (PF00071, IPR001806, SM00173): Ras family
193 RPN1oncoprotein180.43193.013Ribophorin_I (PF04597, IPR007676): Ribophorin I
CtIP_N (PF10482, IPR019518): Tumour-suppressor protein CtIP N-terminal domain
194 RPS3Ainteractor100.35671.743Ribosomal_S3Ae (PF01015, IPR001593): Ribosomal S3Ae family
195 RPS6KA5interactor110.400173.713Choline_kinase (PF01633): Choline/ethanolamine kinase
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
196 RTN4suppressor80.42957.023CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
Reticulon (PF02453, IPR003388): Reticulon
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
197 RUVBL2oncoprotein150.38551.555TIP49 (PF06068, IPR010339): TIP49 C-terminus
198 S100A10oncoprotein40.6671.000S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
199 S100A11suppressor40.6671.167S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
200 S100A2suppressor200S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
201 SCGNinteractor100EF-hand_5 (PF13202, IPR002048): EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_10 (PF14788): EF hand
202 SERPINH1interactor70.33312.260Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
203 SFNsuppressor90.35748.60714-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
204 SFXN1interactor201.317Mtc (PF03820, IPR004686): Tricarboxylate carrier
205 SHMT2interactor160.158192.057SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase
206 SLC25A12interactor50.50016.065Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
207 SLC25A13interactor21.0000Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
208 SLC2A1interactor50.60087.193Sugar_tr (PF00083, IPR005828): Sugar (and other) transporter
209 SLC3A2interactor70.47612.809Alpha-amylase (PF00128, IPR006047): Alpha amylase, catalytic domain
DUF3459 (PF11941, IPR022567): Domain of unknown function (DUF3459)
SLC3A2_N (PF16028, IPR031984): Solute carrier family 3 member 2 N-terminus
210 SMAD3oncoprotein330.274412.039MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
211 SMAD4suppressor170.45866.343MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
212 SNAPC5interactor21.0000SNAPc19 (PF15497, IPR029138): snRNA-activating protein complex subunit 19, SNAPc subunit 19
213 SPOPsuppressor50.16738.713BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
MATH (PF00917, IPR002083, SM00061): MATH domain
214 SQRDLinteractor21.0000Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
215 SRA1interactor100.46728.629SRA1 (PF07304, IPR009917): Steroid receptor RNA activator (SRA1)
216 SS18oncoprotein70.4676.529SSXT (PF05030, IPR007726): SSXT protein (N-terminal region)
Rrn6 (PF10214, IPR019350): RNA polymerase I-specific transcription-initiation factor
217 SSX2oncoprotein40.333130.136KRAB (PF01352, IPR001909, SM00349): KRAB box
218 SSX3interactor30.33319.325KRAB (PF01352, IPR001909, SM00349): KRAB box
219 STIP1interactor140.330131.644TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
Wtap (PF17098, IPR029732): Pre-mRNA-splicing regulator WTAP
220 SUMO1interactor90.5367.934Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
221 TACSTD2oncoprotein100Thyroglobulin_1 (PF00086, IPR000716, SM00211): Thyroglobulin type-1 repeat
DUF2749 (PF10907, IPR024475): Protein of unknown function (DUF2749)
222 TAGLN2interactor120.37925.487Calponin (PF00402, IPR000557): Calponin family repeat
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
223 TCP1interactor140.53828.471Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
224 TFRConcoprotein40.3331.797PA (PF02225, IPR003137): PA domain
Peptidase_M28 (PF04389, IPR007484): Peptidase family M28
TFR_dimer (PF04253, IPR007365): Transferrin receptor-like dimerisation domain
DUF3855 (PF12967, IPR024482): Domain of Unknown Function with PDB structure (DUF3855)
225 THRBsuppressor50.5001.277zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
226 TIMM9interactor100zf-Tim10_DDP (PF02953, IPR004217): Tim10/DDP family zinc finger
227 TLE1interactor90.32122.269TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
228 TMED10interactor100EMP24_GP25L (PF01105, IPR009038): emp24/gp25L/p24 family/GOLD
229 TMX1interactor50.7003.000OST3_OST6 (PF04756, IPR021149): OST3 / OST6 family, transporter family
Thioredoxin (PF00085, IPR013766): Thioredoxin
FAM176 (PF14851): FAM176 family
230 TNFSF12suppressor100TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family
231 TPI1interactor120.50918.922TIM (PF00121, IPR000652): Triosephosphate isomerase
232 TPM1protein found in more fusions70.33338.367Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
233 TPM4oncoprotein60.4008.901Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
234 TRIB3interactor50.40011.527Pkinase (PF00069, IPR000719): Protein kinase domain
235 TUBBinteractor150.42952.732Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
236 UBE2Iinteractor270.292315.982UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
237 UQCRC1interactor80.46411.072Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
238 UQCRC2oncoprotein230.352126.949Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
239 UTF1interactor100Myb_DNA-bind_4 (PF13837): Myb/SANT-like DNA-binding domain
240 VAPAinteractor150.34359.403DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
UL45 (PF05473, IPR008646): UL45 protein, carbohydrate-binding C-type lectin-like
Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain
241 VDAC1interactor230.375110.411Porin_3 (PF01459, IPR027246): Eukaryotic porin
242 VDAC2interactor190.48549.947Porin_3 (PF01459, IPR027246): Eukaryotic porin
243 VDAC3protein found in more fusions170.42651.526Porin_3 (PF01459, IPR027246): Eukaryotic porin
244 VIMsuppressor160.190196.082Filament (PF00038, IPR001664): Intermediate filament protein
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
245 VPS37Cinteractor203.707Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
246 YWHABinteractor140.35241.32714-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
Virulence_fact (PF13769, IPR025989): Virulence factor
247 YWHAGprotein found in more fusions170.29274.66114-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
248 YY1protein found in more fusions160.44856.204zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail
249 ZBTB25interactor40.3339.188BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
250 ZC3H14interactor100PWI (PF01480, IPR002483, SM00311): PWI domain
zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger
251 ZDHHC17protein found in more fusions200zf-DHHC (PF01529, IPR001594): DHHC palmitoyltransferase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_3 (PF13606, IPR002110): Ankyrin repeat
Ank_4 (PF13637): Ankyrin repeats (many copies)
252 ZSCAN31interactor100SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain

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