1 |
ARIH2 | parental protein | 67 | 0.057 | 3493.502 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zinc_ribbon_12 (PF11331, IPR021480): Probable zinc-ribbon domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING PRAS (PF15798, IPR026682): Proline-rich AKT1 substrate 1 |
2 |
APEX1 | interactor | 7 | 0.333 | 12.250 | Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family |
3 |
ARAP1 | interactor | 2 | 1.000 | 0 | ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf PH (PF00169, IPR001849, SM00233): PH domain RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) |
4 |
ASB9 | interactor | 5 | 0.700 | 2.500 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) SOCS_box (PF07525, IPR001496): SOCS box |
5 |
BUB1 | oncoprotein | 2 | 0 | 0 | Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1 Pkinase (PF00069, IPR000719): Protein kinase domain |
6 |
CBR3 | interactor | 2 | 1.000 | 0 | adh_short (PF00106, IPR002198): short chain dehydrogenase |
7 |
CCDC33 | interactor | 1 | 0 | 0 | C2 (PF00168, IPR000008, SM00239): C2 domain DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat SlyX (PF04102, IPR007236): SlyX |
8 |
CEP126 | interactor | 2 | 1.000 | 0 | Nop25 (PF09805, IPR019186): Nucleolar protein 12 (25kDa) K1377 (PF15352, IPR028257): Susceptibility to monomelic amyotrophy |
9 |
CUL5 | suppressor | 14 | 0.352 | 43.886 | Cullin (PF00888, IPR001373, SM00182): Cullin family GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
10 |
DISC1 | interactor | 2 | 1.000 | 0 | HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper Mnd1 (PF03962, IPR005647): Mnd1 family TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Tropomyosin (PF00261, IPR000533): Tropomyosin UVR (PF02151, IPR001943): UvrB/uvrC motif CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding |
11 |
DLST | oncoprotein | 2 | 1.000 | 0 | 2-oxoacid_dh (PF00198, IPR001078): 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme DUF4106 (PF13388, IPR025179): Protein of unknown function (DUF4106) |
12 |
EEF1A1 | oncoprotein | 9 | 0.500 | 6.683 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
13 |
EEF1G | protein found in more fusions | 6 | 0.800 | 0.667 | EF1G (PF00647, IPR001662): Elongation factor 1 gamma, conserved domain GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein |
14 |
EHD1 | interactor | 5 | 0.667 | 1.667 | Gp-FAR-1 (PF05823, IPR008632): Nematode fatty acid retinoid binding protein (Gp-FAR-1) Gtr1_RagA (PF04670, IPR006762): Gtr1/RagA G protein conserved region Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand EHD_N (PF16880, IPR031692): N-terminal EH-domain containing protein |
15 |
EML4 | oncoprotein | 3 | 1.000 | 0 | HELP (PF03451, IPR005108): HELP motif Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup SlyX (PF04102, IPR007236): SlyX WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
16 |
ENSA | interactor | 1 | 0 | 0 | Endosulfine (PF04667, IPR006760): cAMP-regulated phosphoprotein/endosulfine conserved region |
17 |
GFI1 | interactor | 1 | 0 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |
18 |
HK2 | interactor | 4 | 0.667 | 1.667 | Hexokinase_1 (PF00349, IPR022672): Hexokinase Hexokinase_2 (PF03727, IPR022673): Hexokinase |
19 |
IL4R | oncoprotein | 2 | 1.000 | 0 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain IL4Ra_N (PF09238, IPR015319): Interleukin-4 receptor alpha chain, N-terminal |
20 |
KAT5 | oncoprotein | 8 | 0.619 | 6.833 | MOZ_SAS (PF01853, IPR002717): MOZ/SAS family Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain |
21 |
KCNQ2 | interactor | 1 | 0 | 0 | Ion_trans (PF00520, IPR005821): Ion transport protein KCNQ_channel (PF03520, IPR013821): KCNQ voltage-gated potassium channel KCNQC3-Ank-G_bd (PF11956, IPR020969): Ankyrin-G binding motif of KCNQ2-3 KCNQ2_u3 (PF16642): Unstructured region on Potassium channel subunit alpha KvLQT2 |
22 |
LOC147791 | interactor | 1 | 0 | 0 | NA |
23 |
MDM2 | oncoprotein | 19 | 0.294 | 78.386 | Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
24 |
NEDD8 | interactor | 11 | 0.422 | 18.052 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
25 |
NOTCH1 | oncoprotein | 5 | 0.667 | 1.000 | Ank (PF00023, IPR002110, SM00248): Ankyrin repeat EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_2 (PF07974, IPR013111): EGF-like domain EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain NOD (PF06816, IPR010660): NOTCH protein NODP (PF07684, IPR011656): NOTCH protein TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Notch (PF00066, IPR000800, SM00004): LNR domain DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454) hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) |
26 |
NTRK1 | oncoprotein | 18 | 0.213 | 93.219 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
27 |
NUBP1 | interactor | 4 | 0.667 | 1.667 | DUF258 (PF03193, IPR004881): Protein of unknown function, DUF258 ParA (PF10609, IPR019591): NUBPL iron-transfer P-loop NTPase |
28 |
PABPN1 | interactor | 4 | 1.000 | 0 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain Shadoo (PF14999, IPR029238): Shadow of prion protein, neuroprotective |
29 |
PAPSS2 | interactor | 2 | 1.000 | 0 | APS_kinase (PF01583, IPR002891): Adenylylsulphate kinase ATP-sulfurylase (PF01747, IPR024951): ATP-sulfurylase DUF258 (PF03193, IPR004881): Protein of unknown function, DUF258 YscJ_FliF (PF01514, IPR006182): Secretory protein of YscJ/FliF family PUA_2 (PF14306, IPR025980): PUA-like domain |
30 |
PARP6 | interactor | 1 | 0 | 0 | PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain |
31 |
PDLIM1 | interactor | 4 | 1.000 | 0 | LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749) |
32 |
PHF7 | interactor | 3 | 0.667 | 0.667 | zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger zf-HC5HC2H (PF13771): PHD-like zinc-binding domain |
33 |
PML | oncoprotein | 7 | 0.733 | 2.083 | zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
34 |
PPP2R1A | oncoprotein | 8 | 0.536 | 8.369 | TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain HEAT (PF02985, IPR000357): HEAT repeat HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
35 |
PTN | oncoprotein | 2 | 0 | 0 | PTN_MK_C (PF01091, IPR020090): PTN/MK heparin-binding protein family, C-terminal domain PTN_MK_N (PF05196, IPR020089): PTN/MK heparin-binding protein family, N-terminal domain |
36 |
RAB40A | oncoprotein | 3 | 1.000 | 0 | Ras (PF00071, IPR001806, SM00173): Ras family SOCS_box (PF07525, IPR001496): SOCS box |
37 |
REL | interactor | 1 | 0 | 0 | RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
38 |
RHEB | interactor | 1 | 0 | 0 | Ras (PF00071, IPR001806, SM00173): Ras family |
39 |
RPL8 | interactor | 6 | 0.600 | 2.483 | Ribosomal_L2 (PF00181, IPR022666): Ribosomal Proteins L2, RNA binding domain Ribosomal_L2_C (PF03947, IPR022669): Ribosomal Proteins L2, C-terminal domain |
40 |
SCAMP2 | interactor | 1 | 0 | 0 | SCAMP (PF04144, IPR007273): SCAMP family KfrA_N (PF11740, IPR021104): Plasmid replication region DNA-binding N-term |
41 |
SGCE | interactor | 1 | 0 | 0 | Sarcoglycan_2 (PF05510, IPR008908): Sarcoglycan alpha/epsilon |
42 |
SLC1A6 | interactor | 1 | 0 | 0 | SDF (PF00375, IPR001991): Sodium:dicarboxylate symporter family |
43 |
SOCS6 | interactor | 5 | 0.700 | 1.733 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SOCS_box (PF07525, IPR001496): SOCS box |
44 |
TCEB1 | interactor | 8 | 0.536 | 9.733 | Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain |
45 |
TCEB2 | interactor | 6 | 0.800 | 1.400 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
46 |
TP53 | oncoprotein | 14 | 0.385 | 32.486 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
47 |
TRIM27 | oncoprotein | 18 | 0.287 | 75.667 | IncA (PF04156, IPR007285): IncA protein SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease |
48 |
TWF2 | interactor | 2 | 1.000 | 0 | Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein |
49 |
UBC | protein found in more fusions | 22 | 0.262 | 123.617 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
50 |
UBE2D1 | interactor | 7 | 0.733 | 3.333 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
51 |
UBE2D2 | oncoprotein | 11 | 0.444 | 16.867 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
52 |
UBE2D3 | interactor | 6 | 0.800 | 0.800 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
53 |
UBE2D4 | interactor | 4 | 0.667 | 0.667 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
54 |
UBE2E1 | protein found in more fusions | 3 | 1.000 | 0 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein |
55 |
UBE2E2 | protein found in more fusions | 4 | 1.000 | 0 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
56 |
UBE2E3 | interactor | 5 | 1.000 | 0 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
57 |
UBE2L3 | interactor | 5 | 1.000 | 0 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
58 |
UBE2L6 | protein found in more fusions | 3 | 1.000 | 0 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
59 |
UBE2N | protein found in more fusions | 7 | 0.800 | 1.667 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
60 |
UBE2R2 | protein found in more fusions | 4 | 1.000 | 0 | NOA36 (PF06524, IPR010531): NOA36 protein UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
61 |
UBE2T | interactor | 4 | 1.000 | 0 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
62 |
UBE2V1 | interactor | 4 | 0.833 | 0.400 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
63 |
UGP2 | protein found in more fusions | 3 | 1.000 | 0 | UDPGP (PF01704, IPR002618): UTP--glucose-1-phosphate uridylyltransferase |
64 |
UTP14A | interactor | 2 | 1.000 | 0 | Utp14 (PF04615, IPR006709): Utp14 protein |
65 |
VCP | protein found in more fusions | 8 | 0.714 | 2.050 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944) |
66 |
WDR91 | interactor | 2 | 1.000 | 0 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat WIYLD (PF10440, IPR018848): Ubiquitin-binding WIYLD domain ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor |
67 |
ZFP41 | interactor | 1 | 0 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |