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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins ARHGAP4 (from a repository: Wed Nov 23 19:37:59 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)5
The number (and %) of the onco-proteins3 (60.00 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)7 (70.00 %)
The number (and %) of affected PPIs5 (71.43 %)
The number of possible different fusions4
PPI diameter2
PPI radius1
The average degree of PPI1.600
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients5 (100.00 %)
The number (and %) of a zero Betweenness Centrality4 (80.00 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: ARHGAP4 All fusions
Proteins found in more fusions FMNL1 (see 1 fusions); ARHGAP4 (see 5 fusions); MAP3K1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 ARHGAP4parental protein5012.000DASH_Spc19 (PF08287, IPR013251): Spc19
FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain
Occludin_ELL (PF07303, IPR010844): Occludin homology domain
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
2 FMNL1protein found in more fusions200CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Drf_FH3 (PF06367, IPR010472, SM01139): Diaphanous FH3 Domain
Drf_GBD (PF06371, IPR010473, SM01140): Diaphanous GTPase-binding Domain
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
FH2 (PF02181, IPR015425, SM00498): Formin Homology 2 Domain
SlyX (PF04102, IPR007236): SlyX
FNIP_M (PF14637, IPR028085): Folliculin-interacting protein middle domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
ABC_tran_CTD (PF16326, IPR032524): ABC transporter C-terminal domain
3 MAP3K1oncoprotein200zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
Pkinase (PF00069, IPR000719): Protein kinase domain
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
Phostensin_N (PF13916, IPR025903): PP1-regulatory protein, Phostensin N-terminal
4 PCBP1oncoprotein100Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein
KH_2 (PF07650, IPR004044): KH domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
5 SCARNA22interactor100NA

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