1 |
APC | parental protein | 168 | 0.030 | 24110.735 | APC_15aa (PF05972, IPR009240): APC 15 residue motif APC_basic (PF05956, IPR009234): APC basic domain APC_r (PF05923): APC repeat Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) EB1_binding (PF05937, IPR009232): EB-1 Binding Domain FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) SAMP (PF05924, IPR009224): SAMP Motif Suppressor_APC (PF11414, IPR026831): Adenomatous polyposis coli tumour suppressor protein AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term SAS4 (PF15460, IPR029184): Something about silencing, SAS, complex subunit 4 Arm_APC_u3 (PF16629): Armadillo-associated region on APC APC_u5 (PF16630): Unstructured region on APC between 1st and 2nd catenin-bdg motifs APC_u9 (PF16633): Unstructured region on APC between 1st two creatine-rich regions APC_u13 (PF16634): Unstructured region on APC between APC_crr and SAMP APC_u14 (PF16635): Unstructured region on APC between SAMP and APC_crr APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6 APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain |
2 |
ACTN1 | protein found in more fusions | 7 | 0.467 | 5.733 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Dak2 (PF02734, IPR004007, SM01120): DAK2 domain EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand Spectrin (PF00435, IPR002017): Spectrin repeat EF-hand_7 (PF13499, IPR011992): EF-hand domain pair Uds1 (PF15456, IPR029191): Up-regulated During Septation |
3 |
ADGRL1 | interactor | 1 | 0 | 0 | 7tm_2 (PF00002, IPR000832): 7 transmembrane receptor (Secretin family) Gal_Lectin (PF02140, IPR000922): Galactose binding lectin domain GPS (PF01825, IPR000203, SM00303): GPCR proteolysis site, GPS, motif Latrophilin (PF02354, IPR003334): Latrophilin Cytoplasmic C-terminal region OLF (PF02191, IPR003112, SM00284): Olfactomedin-like domain HRM (PF02793, IPR001879, SM00008): Hormone receptor domain GAIN (PF16489, IPR032471): GPCR-Autoproteolysis INducing (GAIN) domain |
4 |
AGFG1 | interactor | 2 | 1.000 | 0 | ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf |
5 |
AGR3 | interactor | 1 | 0 | 0 | Thioredoxin_7 (PF13899): Thioredoxin-like |
6 |
AKAP13 | oncoprotein | 3 | 1.000 | 0 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) IncA (PF04156, IPR007285): IncA protein PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SPT16 (PF08644, IPR013953): FACT complex subunit (SPT16/CDC68) RII_binding_1 (PF10522, IPR018459): RII binding domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
7 |
AMER1 | suppressor | 9 | 0.528 | 10.772 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region WTX (PF09422, IPR019003): WTX protein RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31 |
8 |
ANKRD17 | interactor | 1 | 0 | 0 | Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP LMBR1 (PF04791, IPR006876): LMBR1-like membrane protein Mucin (PF01456, IPR000458): Mucin-like glycoprotein DUF2536 (PF10750, IPR019686): Protein of unknown function (DUF2536) KH_1 (PF00013, IPR004088, SM00322): KH domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6 |
9 |
ANKRD28 | interactor | 7 | 0.476 | 8.400 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
10 |
ANXA7 | suppressor | 2 | 1.000 | 0 | Annexin (PF00191, IPR018502, SM00335): Annexin |
11 |
AP2B1 | interactor | 10 | 0.289 | 24.502 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain B2-adapt-app_C (PF09066, IPR015151, SM01020): Beta2-adaptin appendage, C-terminal sub-domain |
12 |
AP2M1 | protein found in more fusions | 18 | 0.228 | 84.138 | Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain |
13 |
ARHGAP21 | interactor | 8 | 0.357 | 11.169 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain MAJIN (PF15077, IPR027816): Membrane-anchored junction protein PH_9 (PF15410): Pleckstrin homology domain |
14 |
ARHGEF4 | oncoprotein | 1 | 0 | 0 | PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
15 |
AXIN1 | suppressor | 19 | 0.333 | 65.317 | Axin_b-cat_bind (PF08833, IPR014936): Axin beta-catenin binding domain RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain DIX (PF00778, IPR001158, SM00021): DIX domain AXIN1_TNKS_BD (PF16646, IPR032101): Axin-1 tankyrase binding domain |
16 |
AXIN2 | suppressor | 6 | 0.733 | 2.833 | Axin_b-cat_bind (PF08833, IPR014936): Axin beta-catenin binding domain RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain THP2 (PF09432, IPR018557): Tho complex subunit THP2 DIX (PF00778, IPR001158, SM00021): DIX domain AXIN1_TNKS_BD (PF16646, IPR032101): Axin-1 tankyrase binding domain |
17 |
BBX | interactor | 2 | 1.000 | 0 | DUF2028 (PF09667, IPR019102): Domain of unknown function (DUF2028) HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box |
18 |
BTRC | oncoprotein | 14 | 0.397 | 26.455 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like |
19 |
BUB1 | oncoprotein | 5 | 1.000 | 0 | Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1 Pkinase (PF00069, IPR000719): Protein kinase domain |
20 |
BUB1B | oncoprotein | 9 | 0.429 | 13.389 | Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1 Mad3_BUB1_II (PF08171, IPR012572): Mad3/BUB1 homology region 2 Pkinase (PF00069, IPR000719): Protein kinase domain XhlA (PF10779, IPR019715): Haemolysin XhlA CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167 |
21 |
BUB3 | interactor | 7 | 0.476 | 7.783 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
22 |
C4A | interactor | 1 | 0 | 0 | A2M (PF00207, IPR001599): Alpha-2-macroglobulin family A2M_comp (PF07678, IPR011626): A-macroglobulin complement component A2M_N (PF01835, IPR002890): MG2 domain A2M_N_2 (PF07703, IPR011625): Alpha-2-macroglobulin family N-terminal region A2M_recep (PF07677, IPR009048): A-macroglobulin receptor ANATO (PF01821, IPR000020, SM00104): Anaphylotoxin-like domain NTR (PF01759, IPR018933, SM00206): UNC-6/NTR/C345C module Thiol-ester_cl (PF10569, IPR019565): Alpha-macro-globulin thiol-ester bond-forming region |
23 |
CASC3 | oncoprotein | 2 | 1.000 | 0 | Btz (PF09405, IPR018545, SM01044): CASC3/Barentsz eIF4AIII binding UPF0560 (PF10577, IPR018890): Uncharacterised protein family UPF0560 PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
24 |
CCL5 | interactor | 1 | 0 | 0 | IL8 (PF00048, IPR001811, SM00199): Small cytokines (intecrine/chemokine), interleukin-8 like |
25 |
CEP128 | interactor | 16 | 0.217 | 76.400 | DUF1129 (PF06570, IPR009214): Protein of unknown function (DUF1129) DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein SpoOE-like (PF09388, IPR018540): Spo0E like sporulation regulatory protein DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968) TraF_2 (PF13729, IPR032811): F plasmid transfer operon, TraF, protein GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) HAUS6_N (PF14661, IPR028163): HAUS augmin-like complex subunit 6 N-terminus HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
26 |
CEP250 | interactor | 7 | 0.333 | 10.786 | ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1 DivIC (PF04977, IPR007060): Septum formation initiator DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) EHN (PF06441, IPR010497): Epoxide hydrolase N terminus ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain SlyX (PF04102, IPR007236): SlyX Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal TSC22 (PF01166, IPR000580): TSC-22/dip/bun family CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Endonuc_Holl (PF10107, IPR019287): Endonuclease related to archaeal Holliday junction resolvase DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570) DGF-1_C (PF11040, IPR021053): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472) Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
27 |
CFTR | suppressor | 8 | 0.381 | 11.286 | ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region ABC_tran (PF00005, IPR003439): ABC transporter Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain |
28 |
CGNL1 | interactor | 1 | 0 | 0 | Abhydrolase_4 (PF08386, IPR013595): TAP-like protein Myosin_tail_1 (PF01576, IPR002928): Myosin tail |
29 |
COG4 | interactor | 2 | 1.000 | 0 | COG4 (PF08318, IPR013167, SM00762): COG4 transport protein RINT1_TIP1 (PF04437, IPR007528): RINT-1 / TIP-1 family COG5 (PF10392, IPR019465): Golgi transport complex subunit 5 |
30 |
COG5 | interactor | 2 | 1.000 | 0 | AceK (PF06315, IPR010452): Isocitrate dehydrogenase kinase/phosphatase (AceK) COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2 COG5 (PF10392, IPR019465): Golgi transport complex subunit 5 DUF3800 (PF12686, IPR024524): Protein of unknown function (DUF3800) |
31 |
COPS5 | protein found in more fusions | 27 | 0.154 | 225.795 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
32 |
CREBBP | suppressor | 9 | 0.429 | 12.650 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) |
33 |
CSNK1A1 | suppressor | 9 | 0.417 | 11.413 | Pkinase (PF00069, IPR000719): Protein kinase domain |
34 |
CSNK1E | protein found in more fusions | 11 | 0.444 | 16.452 | APH (PF01636, IPR002575): Phosphotransferase enzyme family Pkinase (PF00069, IPR000719): Protein kinase domain |
35 |
CSNK2A1 | oncoprotein | 13 | 0.242 | 35.921 | Pkinase (PF00069, IPR000719): Protein kinase domain |
36 |
CSNK2B | interactor | 11 | 0.356 | 20.941 | CK_II_beta (PF01214, IPR000704, SM01085): Casein kinase II regulatory subunit |
37 |
CTBP1 | protein found in more fusions | 6 | 0.600 | 3.000 | 2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D |
38 |
CTNNA1 | oncoprotein | 13 | 0.485 | 20.529 | Vinculin (PF01044, IPR006077): Vinculin family |
39 |
CTNNB1 | oncoprotein | 31 | 0.194 | 295.459 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat |
40 |
CYP17A1 | interactor | 1 | 0 | 0 | p450 (PF00067, IPR001128): Cytochrome P450 |
41 |
CYTH2 | interactor | 2 | 1.000 | 0 | NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region PH (PF00169, IPR001849, SM00233): PH domain Sec7 (PF01369, IPR000904, SM00222): Sec7 domain |
42 |
DIRAS3 | suppressor | 2 | 1.000 | 0 | ArgK (PF03308, IPR005129): ArgK protein Ras (PF00071, IPR001806, SM00173): Ras family VirE (PF05272, IPR007936): Virulence-associated protein E |
43 |
DKK3 | suppressor | 1 | 0 | 0 | Dickkopf_N (PF04706, IPR006796): Dickkopf N-terminal cysteine-rich region HSCB_C (PF07743, IPR009073): HSCB C-terminal oligomerisation domain Nodulin_late (PF07127, IPR009810): Late nodulin protein VCX_VCY (PF15231, IPR026653): Variable charge X/Y family |
44 |
DLG3 | interactor | 3 | 0.667 | 1.000 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) MAGUK_N_PEST (PF10608, IPR019590): Polyubiquitination (PEST) N-terminal domain of MAGUK PDZ_assoc (PF10600, IPR019583): PDZ-associated domain of NMDA receptors Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
45 |
DLGAP1 | oncoprotein | 3 | 0.667 | 1.000 | Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein GKAP (PF03359, IPR005026): Guanylate-kinase-associated protein (GKAP) protein |
46 |
DST | oncoprotein | 3 | 0.667 | 0.500 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) ZYG-11_interact (PF05884, IPR008574): Interactor of ZYG-11 DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family GAS2 (PF02187, IPR003108, SM00243): Growth-Arrest-Specific Protein 2 Domain Laminin_II (PF06009, IPR010307): Laminin Domain II Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein Phasin (PF05597, IPR008769): Poly(hydroxyalcanoate) granule associated protein (phasin) Spectrin (PF00435, IPR002017): Spectrin repeat Nbl1_Borealin_N (PF10444, IPR018851): Nbl1 / Borealin N terminal XhlA (PF10779, IPR019715): Haemolysin XhlA zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein Plectin (PF00681, IPR001101, SM00250): Plectin repeat DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446) FTA4 (PF13093, IPR025207): Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 EF-hand_7 (PF13499, IPR011992): EF-hand domain pair DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) NYD-SP28 (PF14772): Sperm tail Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein |
47 |
DVL2 | interactor | 12 | 0.382 | 23.952 | DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Dishevelled (PF02377, IPR003351): Dishevelled specific domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DIX (PF00778, IPR001158, SM00021): DIX domain Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal |
48 |
EEF1D | protein found in more fusions | 7 | 0.400 | 7.833 | EF1_GNE (PF00736, IPR014038, SM00888): EF-1 guanine nucleotide exchange domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region |
49 |
EPAS1 | suppressor | 8 | 0.476 | 6.357 | Corona_I (PF03187, IPR004876): Corona nucleocapsid I protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 PAS_11 (PF14598): PAS domain |
50 |
ERBIN | oncoprotein | 8 | 0.429 | 9.222 | LRR_1 (PF00560, IPR001611): Leucine Rich Repeat Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat |
51 |
EXPH5 | interactor | 1 | 0 | 0 | FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger |
52 |
FAM214A | interactor | 2 | 1.000 | 0 | Chromosome_seg (PF13889): Chromosome segregation during meiosis DUF4210 (PF13915, IPR025261): Domain of unknown function (DUF4210) |
53 |
FAM83B | interactor | 4 | 1.000 | 0 | Cauli_AT (PF03233, IPR004917): Aphid transmission protein DUF1669 (PF07894, IPR012461): Protein of unknown function (DUF1669) |
54 |
FBXO30 | interactor | 2 | 1.000 | 0 | zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger zf-C2H2_4 (PF13894): C2H2-type zinc finger DUF4644 (PF15486, IPR027978): Domain of unknown function (DUF4644) zf-TRAF_2 (PF15965, IPR001293): TRAF-like zinc-finger F-box_4 (PF15966, IPR001810): F-box |
55 |
FBXW11 | interactor | 21 | 0.232 | 114.506 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like |
56 |
FHOD1 | interactor | 3 | 1.000 | 0 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator FH2 (PF02181, IPR015425, SM00498): Formin Homology 2 Domain |
57 |
FLNA | suppressor | 14 | 0.297 | 47.290 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Filamin (PF00630, IPR017868): Filamin/ABP280 repeat |
58 |
GIGYF2 | interactor | 3 | 0.667 | 0.500 | DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) GYF (PF02213, IPR003169, SM00444): GYF domain Macoilin (PF09726, IPR019130): Transmembrane protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 DUF3801 (PF12687, IPR024234): Protein of unknown function (DUF3801) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term AAA_23 (PF13476): AAA domain ARGLU (PF15346): Arginine and glutamate-rich 1 PRTase_3 (PF15610, IPR028944): PRTase ComF-like Ferlin_C (PF16165, IPR032362): Ferlin C-terminus |
59 |
GOLGA2 | interactor | 4 | 0.500 | 2.500 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion GOLGA2L5 (PF15070, IPR024858): Putative golgin subfamily A member 2-like protein 5 |
60 |
GSK3B | suppressor | 13 | 0.424 | 26.461 | Pkinase (PF00069, IPR000719): Protein kinase domain |
61 |
HECTD1 | interactor | 10 | 0.306 | 23.583 | Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein MIB_HERC2 (PF06701, IPR010606): Mib_herc2 NOA36 (PF06524, IPR010531): NOA36 protein Sad1_UNC (PF07738, IPR012919): Sad1 / UNC-like C-terminal HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal |
62 |
HGS | interactor | 6 | 0.467 | 7.667 | FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif VHS (PF00790, IPR002014, SM00288): VHS domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate PIEZO (PF15917, IPR031805): Piezo |
63 |
HNRNPM | interactor | 12 | 0.303 | 31.655 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region |
64 |
HOXC6 | interactor | 1 | 0 | 0 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
65 |
HSPA5 | oncoprotein | 15 | 0.275 | 50.033 | HSP70 (PF00012, IPR013126): Hsp70 protein |
66 |
HTRA2 | suppressor | 3 | 1.000 | 0 | Peptidase_S32 (PF05579, IPR008760): Equine arteritis virus serine endopeptidase S32 PDZ_2 (PF13180, IPR001478): PDZ domain Trypsin_2 (PF13365): Trypsin-like peptidase domain |
67 |
IL24 | suppressor | 1 | 0 | 0 | IL22 (PF14565, IPR020453): Interleukin 22 IL-10-related T-cell-derived-inducible factor |
68 |
ING5 | suppressor | 3 | 0.667 | 1.000 | ING (PF12998, IPR024610): Inhibitor of growth proteins N-terminal histone-binding |
69 |
JUP | suppressor | 11 | 0.382 | 21.525 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
70 |
KCTD1 | interactor | 4 | 1.000 | 0 | BTB_2 (PF02214, IPR003131): BTB/POZ domain |
71 |
KIAA1328 | interactor | 1 | 0 | 0 | FUSC (PF04632, IPR006726): Fusaric acid resistance protein family KIAA1328 (PF15369, IPR032736): Uncharacterised protein KIAA1328 |
72 |
KIF5B | interactor | 9 | 0.361 | 18.667 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Sec2p (PF06428, IPR009449): GDP/GTP exchange factor Sec2p Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain DUF3584 (PF12128, IPR021979): Protein of unknown function (DUF3584) HAUS-augmin3 (PF14932, IPR032733): HAUS augmin-like complex subunit 3 DUF4226 (PF10774, IPR019710): Domain of unknown function (DUF4226) PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain |
73 |
KIF7 | suppressor | 3 | 0.667 | 0.500 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724) MMR_HSR1_C (PF08438, IPR013646): GTPase of unknown function C-terminal Nbs1_C (PF08599, IPR013908): DNA damage repair protein Nbs1 XhlA (PF10779, IPR019715): Haemolysin XhlA Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain YlqD (PF11068, IPR021297): YlqD protein DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) |
74 |
KIFAP3 | interactor | 4 | 0.667 | 1.667 | KAP (PF05804): Kinesin-associated protein (KAP) |
75 |
KRT13 | interactor | 2 | 1.000 | 0 | Filament (PF00038, IPR001664): Intermediate filament protein FliD_N (PF02465, IPR003481): Flagellar hook-associated protein 2 N-terminus Keratin_2_head (PF16208, IPR032444): Keratin type II head |
76 |
KRT14 | interactor | 5 | 0.700 | 1.352 | Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region Keratin_2_head (PF16208, IPR032444): Keratin type II head |
77 |
KRT15 | interactor | 6 | 0.467 | 7.667 | Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head |
78 |
KRT17 | interactor | 4 | 0.500 | 1.619 | DUF1798 (PF08807, IPR014913): Bacterial domain of unknown function (DUF1798) Filament (PF00038, IPR001664): Intermediate filament protein |
79 |
KRT19 | suppressor | 4 | 1.000 | 0 | Filament (PF00038, IPR001664): Intermediate filament protein |
80 |
KRT23 | interactor | 1 | 0 | 0 | Filament (PF00038, IPR001664): Intermediate filament protein |
81 |
KRT5 | interactor | 6 | 0.467 | 6.952 | Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head |
82 |
LAMA3 | interactor | 1 | 0 | 0 | Laminin_B (PF00052, IPR000034): Laminin B (Domain IV) Laminin_G_2 (PF02210, IPR001791): Laminin G domain Laminin_I (PF06008, IPR009254): Laminin Domain I Laminin_II (PF06009, IPR010307): Laminin Domain II PPE (PF00823, IPR000030): PPE family Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain Laminin_N (PF00055, IPR008211, SM00136): Laminin N-terminal (Domain VI) Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin TSNAXIP1_N (PF15739, IPR032755): Translin-associated factor X-interacting N-terminus |
83 |
LAMA4 | interactor | 1 | 0 | 0 | DUF883 (PF05957, IPR010279): Bacterial protein of unknown function (DUF883) ZapB (PF06005, IPR009252): Cell division protein ZapB Laminin_G_2 (PF02210, IPR001791): Laminin G domain Laminin_I (PF06008, IPR009254): Laminin Domain I Laminin_II (PF06009, IPR010307): Laminin Domain II Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein |
84 |
LATS2 | suppressor | 10 | 0.361 | 18.400 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain |
85 |
LIN7C | interactor | 4 | 0.667 | 1.400 | His_Phos_2 (PF00328, IPR000560): Histidine phosphatase superfamily (branch 2) L27 (PF02828, IPR014775, SM00569): L27 domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) |
86 |
MACF1 | oncoprotein | 3 | 0.667 | 1.000 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain CTV_P33 (PF07184, IPR010803): Citrus tristeza virus P33 protein DnaI_N (PF07319, IPR009928): Primosomal protein DnaI N-terminus DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF19 (PF01579, IPR002542): Domain of unknown function (DUF19) FliJ (PF02050, IPR012823): Flagellar FliJ protein GAS2 (PF02187, IPR003108, SM00243): Growth-Arrest-Specific Protein 2 Domain Laminin_II (PF06009, IPR010307): Laminin Domain II Peptidase_S49 (PF01343, IPR002142): Peptidase family S49 Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Spectrin (PF00435, IPR002017): Spectrin repeat SYF2 (PF08231, IPR013260): SYF2 splicing factor KxDL (PF10241, IPR019371): Uncharacterized conserved protein Plectin (PF00681, IPR001101, SM00250): Plectin repeat Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like DUF3813 (PF12758, IPR024217): Protein of unknown function (DUF3813) EF-hand_7 (PF13499, IPR011992): EF-hand domain pair TEX12 (PF15219, IPR029193): Testis-expressed 12 HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
87 |
MAD1L1 | suppressor | 5 | 0.500 | 3.000 | MAD (PF05557, IPR008672): Mitotic checkpoint protein Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14 |
88 |
MAD2L1 | oncoprotein | 7 | 0.533 | 7.000 | HORMA (PF02301, IPR003511): HORMA domain |
89 |
MAPRE1 | oncoprotein | 16 | 0.248 | 67.722 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EB1 (PF03271, IPR004953): EB1-like C-terminal motif SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
90 |
MAPRE2 | protein found in more fusions | 5 | 0.500 | 2.667 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EB1 (PF03271, IPR004953): EB1-like C-terminal motif |
91 |
MARK2 | protein found in more fusions | 7 | 0.533 | 6.000 | DUF702 (PF05142, IPR007818): Domain of unknown function (DUF702) KA1 (PF02149, IPR001772): Kinase associated domain 1 Pkinase (PF00069, IPR000719): Protein kinase domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain |
92 |
MBD4 | suppressor | 2 | 1.000 | 0 | HhH-GPD (PF00730, IPR003265): HhH-GPD superfamily base excision DNA repair protein MBD (PF01429, IPR001739, SM00391): Methyl-CpG binding domain |
93 |
MBD5 | interactor | 1 | 0 | 0 | MBD (PF01429, IPR001739, SM00391): Methyl-CpG binding domain Pap_E4 (PF02711, IPR003861): E4 protein PWWP (PF00855, IPR000313, SM00293): PWWP domain DUF3439 (PF11921, IPR024592): Domain of unknown function (DUF3439) |
94 |
MCM3AP | interactor | 2 | 1.000 | 0 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAC3_GANP (PF03399, IPR005062): SAC3/GANP family G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor CID_GANP (PF16766, IPR031910): Binding region of GANP to ENY2 NupH_GANP (PF16768, IPR031908): Nucleoporin homology of Germinal-centre associated nuclear protein MCM3AP_GANP (PF16769, IPR031907): MCM3AP domain of GANP |
95 |
MRPL18 | interactor | 2 | 1.000 | 0 | Ribosomal_L18p (PF00861, IPR005484): Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast |
96 |
MUC1 | oncoprotein | 4 | 0.833 | 0.333 | SEA (PF01390, IPR000082, SM00200): SEA domain Shisa (PF13908, IPR026910): Wnt and FGF inhibitory regulator Collectrin (PF16959, IPR031588): Renal amino acid transporter |
97 |
MYH10 | interactor | 4 | 0.833 | 0.286 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
98 |
MYH11 | oncoprotein | 5 | 0.600 | 3.167 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator |
99 |
MYO6 | protein found in more fusions | 6 | 0.500 | 4.000 | BUD22 (PF09073, IPR015158): BUD22 IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Rad9 (PF04139, IPR007268): Rad9 Sec62 (PF03839, IPR004728): Translocation protein Sec62 XhlA (PF10779, IPR019715): Haemolysin XhlA Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) DUF4887 (PF16228, IPR032615): Domain of unknown function (DUF4887) Myosin-VI_CBD (PF16521, IPR032412): Myosin VI cargo binding domain |
100 |
NAT2 | oncoprotein | 1 | 0 | 0 | Acetyltransf_2 (PF00797, IPR001447): N-acetyltransferase |
101 |
NAV1 | oncoprotein | 4 | 0.500 | 1.352 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) ZapB (PF06005, IPR009252): Cell division protein ZapB Fez1 (PF06818): Fez1 AAA_16 (PF13191): AAA ATPase domain DUF4201 (PF13870, IPR025254): Domain of unknown function (DUF4201) |
102 |
NAV2 | interactor | 3 | 0.667 | 1.000 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Laminin_II (PF06009, IPR010307): Laminin Domain II KLRAQ (PF10205, IPR019343): Predicted coiled-coil domain-containing protein ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding AAA_14 (PF13173): AAA domain |
103 |
NAV3 | oncoprotein | 2 | 1.000 | 0 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Fez1 (PF06818): Fez1 PhoH (PF02562, IPR003714): PhoH-like protein Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein AAA_14 (PF13173): AAA domain |
104 |
NCKAP5 | interactor | 1 | 0 | 0 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor SurA_N_2 (PF13623): SurA N-terminal domain NCKAP5 (PF15246, IPR032769): Nck-associated protein 5, Peripheral clock protein DUF4789 (PF16033, IPR031993): Domain of unknown function (DUF4789) |
105 |
NCKAP5L | interactor | 6 | 0.400 | 4.336 | GCN5L1 (PF06320, IPR009395): GCN5-like protein 1 (GCN5L1) NCKAP5 (PF15246, IPR032769): Nck-associated protein 5, Peripheral clock protein |
106 |
ND4 | interactor | 1 | 0 | 0 | NA |
107 |
NEB | oncoprotein | 1 | 0 | 0 | Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24 Nebulin (PF00880, IPR000900, SM00227): Nebulin repeat Shal-type (PF11601, IPR021645): Shal-type voltage-gated potassium channels, N-terminal DUF3410 (PF11890, IPR024531): Domain of unknown function (DUF3410) DUF3417 (PF11897, IPR024517): Protein of unknown function (DUF3417) G-patch_2 (PF12656, IPR026822): DExH-box splicing factor binding site NFRKB_winged (PF14465, IPR025220): NFRKB Winged Helix-like SH3_9 (PF14604, IPR001452): Variant SH3 domain |
108 |
NOSTRIN | interactor | 1 | 0 | 0 | DnaI_N (PF07319, IPR009928): Primosomal protein DnaI N-terminus DUF1778 (PF08681, IPR014795): Protein of unknown function (DUF1778) FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain HR1 (PF02185, IPR011072, SM00742): Hr1 repeat FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain GIT1_C (PF12205, IPR022018): G protein-coupled receptor kinase-interacting protein 1 C term SH3_9 (PF14604, IPR001452): Variant SH3 domain |
109 |
NUP107 | interactor | 13 | 0.410 | 31.652 | Nup84_Nup100 (PF04121, IPR007252): Nuclear pore protein 84 / 107 |
110 |
NUP153 | protein found in more fusions | 15 | 0.363 | 39.683 | Nup153 (PF08604, IPR013913): Nucleoporin Nup153-like Nup_retrotrp_bd (PF10599, IPR018892): Retro-transposon transporting motif zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region |
111 |
NUP214 | oncoprotein | 8 | 0.762 | 2.186 | dCache_2 (PF08269, IPR004010, SM01049): Cache domain HisKA (PF00512, IPR003661, SM00388): His Kinase A (phospho-acceptor) domain MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region Mustang (PF15682, IPR031394): Musculoskeletal, temporally activated-embryonic nuclear protein 1 NUP214 (PF16755): Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 |
112 |
NUP54 | interactor | 8 | 0.464 | 13.452 | Regulator_TrmB (PF11495, IPR021586): Archaeal transcriptional regulator TrmB KRTAP (PF11759, IPR021743): Keratin-associated matrix Nup54 (PF13874, IPR025712): Nucleoporin complex subunit 54 SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
113 |
NUP58 | interactor | 8 | 0.536 | 9.300 | Nucleoporin_FG2 (PF15967): Nucleoporin FG repeated region |
114 |
NUP98 | suppressor | 9 | 0.500 | 12.769 | Nucleoporin2 (PF04096, IPR007230): Nucleoporin autopeptidase Nup96 (PF12110, IPR021967): Nuclear protein 96 ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region Keratin_2_head (PF16208, IPR032444): Keratin type II head |
115 |
NUPL2 | interactor | 7 | 0.524 | 8.452 | zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) |
116 |
PCNA | oncoprotein | 7 | 0.400 | 9.000 | PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain |
117 |
PDLIM2 | protein found in more fusions | 2 | 0 | 0 | LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749) |
118 |
PKP2 | interactor | 7 | 0.381 | 11.067 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat DUF383 (PF04063, IPR007205): Domain of unknown function (DUF383) |
119 |
PNISR | interactor | 2 | 1.000 | 0 | DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Pap_E4 (PF02711, IPR003861): E4 protein Membralin (PF09746, IPR019144): Tumour-associated protein YqfQ (PF14181, IPR025571): YqfQ-like protein PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR |
120 |
POM121 | interactor | 4 | 0.500 | 1.833 | Ice_nucleation (PF00818, IPR000258): Ice nucleation protein repeat Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region POM121 (PF15229): POM121 family |
121 |
POM121C | interactor | 4 | 0.667 | 2.000 | T2SSC (PF11356): Type II secretion system protein C Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region POM121 (PF15229): POM121 family |
122 |
PPP1R13B | interactor | 4 | 0.667 | 2.000 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) IncA (PF04156, IPR007285): IncA protein RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) |
123 |
PPP2R5A | interactor | 3 | 0.667 | 0.500 | B56 (PF01603, IPR002554): Protein phosphatase 2A regulatory B subunit (B56 family) |
124 |
PSMD1 | interactor | 6 | 0.533 | 5.067 | PA26 (PF04636, IPR006730): PA26 p53-induced protein (sestrin) PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat HEAT_2 (PF13646): HEAT repeats |
125 |
PTK2 | protein found in more fusions | 3 | 1.000 | 0 | FERM_M (PF00373, IPR019748): FERM central domain Focal_AT (PF03623, IPR005189): Focal adhesion targeting region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase UCMA (PF17085, IPR031386): Unique cartilage matrix associated protein |
126 |
RANBP2 | oncoprotein | 18 | 0.221 | 93.252 | Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others DUF2693 (PF10902, IPR024401): Protein of unknown function (DUF2693) IR1-M (PF12185, IPR022011): Nup358/RanBP2 E3 ligase domain Dmrt1 (PF12374, IPR022114): Double-sex mab3 related transcription factor 1 TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
127 |
RANBP9 | suppressor | 5 | 0.833 | 0.667 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator LisH (PF08513, IPR013720, SM00667): LisH SPRY (PF00622, IPR003877, SM00449): SPRY domain CLTH (PF10607, IPR024964): CTLH/CRA C-terminal to LisH motif domain |
128 |
RBFOX2 | protein found in more fusions | 3 | 1.000 | 0 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fox-1_C (PF12414, IPR025670): Calcitonin gene-related peptide regulator C terminal |
129 |
RBM4B | interactor | 2 | 1.000 | 0 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC (PF00098, IPR001878): Zinc knuckle |
130 |
RNF146 | interactor | 6 | 0.500 | 3.567 | WWE (PF02825, IPR004170, SM00678): WWE domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
131 |
RPA2 | oncoprotein | 18 | 0.183 | 104.319 | RPA_C (PF08784, IPR014892): Replication protein A C terminal tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2 |
132 |
RPGRIP1L | interactor | 7 | 0.476 | 8.833 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor C2 (PF00168, IPR000008, SM00239): C2 domain DivIC (PF04977, IPR007060): Septum formation initiator DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) FtsL (PF04999, IPR011922): Cell division protein FtsL T3SS_needle_F (PF09392, IPR021123): Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 C2-C2_1 (PF11618, IPR021656): First C2 domain of RPGR-interacting protein 1 BNIP2 (PF12496, IPR022181): Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) DUF4497 (PF14924): Protein of unknown function (DUF4497) |
133 |
RPS27 | interactor | 4 | 0.667 | 1.500 | Ribosomal_S27e (PF01667, IPR000592): Ribosomal protein S27 DUF3795 (PF12675, IPR024227): Protein of unknown function (DUF3795) |
134 |
SASS6 | interactor | 2 | 1.000 | 0 | CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SAS-6_N (PF16531, IPR032396): Centriolar protein SAS N-terminal |
135 |
SAV1 | oncoprotein | 5 | 0.400 | 4.667 | WW (PF00397, IPR001202, SM00456): WW domain |
136 |
SCRIB | suppressor | 1 | 0 | 0 | Hormone_3 (PF00159, IPR001955): Pancreatic hormone peptide LRR_1 (PF00560, IPR001611): Leucine Rich Repeat PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) SDA1 (PF05285, IPR007949): SDA1 DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat LRR_9 (PF14580): Leucine-rich repeat AbLIM_anchor (PF16182, IPR032402): Putative adherens-junction anchoring region of AbLIM |
137 |
SEC31A | interactor | 3 | 0.667 | 1.000 | P3A (PF08727, IPR014838): Poliovirus 3A protein like SRA1 (PF07304, IPR009917): Steroid receptor RNA activator (SRA1) Sec16_C (PF12931, IPR024298): Sec23-binding domain of Sec16 Sec16 (PF12932, IPR024340): Vesicle coat trafficking protein Sec16 mid-region |
138 |
SENP1 | protein found in more fusions | 5 | 1.000 | 0 | Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain |
139 |
SETDB1 | interactor | 6 | 0.333 | 10.000 | MBD (PF01429, IPR001739, SM00391): Methyl-CpG binding domain Pre-SET (PF05033, IPR007728): Pre-SET motif SET (PF00856, IPR001214, SM00317): SET domain DUF4537 (PF15057, IPR032770): Domain of unknown function (DUF4537) PNRC (PF15365, IPR028322): Proline-rich nuclear receptor coactivator |
140 |
SFN | suppressor | 15 | 0.220 | 58.869 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
141 |
SIAH1 | suppressor | 6 | 0.600 | 3.333 | Sina (PF03145, IPR018121): Seven in absentia protein family |
142 |
SMC3 | oncoprotein | 8 | 0.357 | 16.533 | SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain |
143 |
SNRNP200 | protein found in more fusions | 5 | 0.500 | 1.033 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF603 (PF04645, IPR006739): Protein of unknown function, DUF603 Sec63 (PF02889, IPR004179, SM00973): Sec63 Brl domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
144 |
SPECC1L | interactor | 4 | 0.833 | 0.500 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding KASH_CCD (PF14662, IPR028168): Coiled-coil region of CCDC155 or KASH Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease DUF4763 (PF15960, IPR031883): Domain of unknown function (DUF4763) |
145 |
SPTBN1 | suppressor | 9 | 0.556 | 8.219 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2 DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Spectrin (PF00435, IPR002017): Spectrin repeat PH_9 (PF15410): Pleckstrin homology domain |
146 |
SPTBN2 | interactor | 3 | 1.000 | 0 | BEX (PF04538, IPR021156): Brain expressed X-linked like family CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Spectrin (PF00435, IPR002017): Spectrin repeat Mating_N (PF12731, IPR024333): Mating-type protein beta 1 DUF4110 (PF13422, IPR025183): Domain of unknown function (DUF4110) PH_9 (PF15410): Pleckstrin homology domain |
147 |
ST14 | interactor | 1 | 0 | 0 | CUB (PF00431, IPR000859, SM00042): CUB domain SEA (PF01390, IPR000082, SM00200): SEA domain Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A Trypsin (PF00089, IPR001254, SM00020): Trypsin |
148 |
STRN | oncoprotein | 4 | 1.000 | 0 | CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) Nucleoporin_N (PF08801, IPR014908): Nup133 N terminal like Striatin (PF08232, IPR013258): Striatin family WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
149 |
STRN3 | interactor | 6 | 0.600 | 5.667 | Striatin (PF08232, IPR013258): Striatin family WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
150 |
STRN4 | interactor | 4 | 1.000 | 0 | CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain Striatin (PF08232, IPR013258): Striatin family WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
151 |
SYNE1 | oncoprotein | 3 | 1.000 | 0 | Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Cytochrom_B562 (PF07361, IPR009155): Cytochrome b562 DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724) DUF745 (PF05335, IPR007999): Protein of unknown function (DUF745) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) Fez1 (PF06818): Fez1 Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein POX (PF07526, IPR006563, SM00574): Associated with HOX Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein RsbU_N (PF08673, IPR014787): Phosphoserine phosphatase RsbU, N-terminal domain Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Spectrin (PF00435, IPR002017): Spectrin repeat THOC7 (PF05615, IPR008501): Tho complex subunit 7 TipAS (PF07739, IPR012925): TipAS antibiotic-recognition domain Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region Adaptin_binding (PF10199, IPR019341): Alpha and gamma adaptin binding protein p34 CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 KASH (PF10541, IPR012315): Nuclear envelope localisation domain DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037) DUF3416 (PF11896, IPR021828): Domain of unknown function (DUF3416) NYD-SP28_assoc (PF14775, IPR029440): Sperm tail C-terminal domain Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease KELK (PF15796, IPR031597): KELK-motif containing domain of MRCK Ser/Thr protein kinase BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 |
152 |
SYNPO | interactor | 12 | 0.348 | 32.319 | Calsarcin (PF05556, IPR008438): Calcineurin-binding protein (Calsarcin) |
153 |
TAF1 | oncoprotein | 4 | 0.667 | 2.000 | Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit LcrG (PF07216, IPR009863): LcrG protein Opi1 (PF08618, IPR013927): Transcription factor Opi1 Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region PRP1_N (PF06424, IPR010491): PRP1 splicing factor, N-terminal TBP-binding (PF09247, IPR009067): TATA box-binding protein binding U3_snoRNA_assoc (PF08297, IPR013268): U3 snoRNA associated Bromodomain (PF00439, IPR001487, SM00297): Bromodomain DUF3591 (PF12157, IPR022591): Protein of unknown function (DUF3591) zf-CCHC_6 (PF15288): Zinc knuckle |
154 |
TELO2 | interactor | 3 | 0.667 | 1.000 | Telomere_reg-2 (PF10193, IPR019337): Telomere length regulation protein HEAT_2 (PF13646): HEAT repeats |
155 |
TFAP2A | suppressor | 8 | 0.357 | 11.717 | TF_AP-2 (PF03299, IPR013854): Transcription factor AP-2 CYYR1 (PF10873, IPR022640): Cysteine and tyrosine-rich protein 1 Peptidase_Prp (PF04327): Cysteine protease Prp |
156 |
TFF1 | oncoprotein | 2 | 0 | 0 | Trefoil (PF00088, IPR000519, SM00018): Trefoil (P-type) domain |
157 |
TNKS | interactor | 5 | 0.833 | 0.500 | Ank (PF00023, IPR002110, SM00248): Ankyrin repeat CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
158 |
TPR | oncoprotein | 6 | 0.533 | 6.667 | Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus ZapB (PF06005, IPR009252): Cell division protein ZapB Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 XhlA (PF10779, IPR019715): Haemolysin XhlA ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein DUF3373 (PF11853, IPR021803): Protein of unknown function (DUF3373) DUF4107 (PF13389, IPR025180): Protein of unknown function (DUF4107) JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082) |
159 |
TRAF1 | oncoprotein | 7 | 0.333 | 10.000 | HypA (PF01155, IPR000688): Hydrogenase/urease nickel incorporation, metallochaperone, hypA SlyX (PF04102, IPR007236): SlyX TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain |
160 |
TRIM21 | interactor | 4 | 0.667 | 0.250 | DUF313 (PF03754, IPR005508): Domain of unknown function (DUF313) SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain Prok-RING_1 (PF14446): Prokaryotic RING finger family 1 zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING |
161 |
TRIM25 | protein found in more fusions | 6 | 0.500 | 5.000 | Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1 Pox_Rif (PF03340, IPR005008): Poxvirus rifampicin resistance protein SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 |
162 |
TUBA4A | interactor | 6 | 0.533 | 2.950 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
163 |
UBC | protein found in more fusions | 22 | 0.148 | 152.544 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
164 |
WIZ | interactor | 3 | 0.667 | 0.500 | AnfO_nitrog (PF09582, IPR014287): Iron only nitrogenase protein AnfO (AnfO_nitrog) C1_2 (PF03107, IPR004146): C1 domain Zn-ribbon_8 (PF09723, IPR013429, SM00834): Zinc ribbon domain Enterotoxin_ST (PF02048, IPR001489): Heat-stable enterotoxin ST zf-C2H2_4 (PF13894): C2H2-type zinc finger |
165 |
XPO1 | interactor | 37 | 0.107 | 529.450 | CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region |
166 |
YWHAQ | interactor | 9 | 0.389 | 18.733 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
167 |
ZNF106 | interactor | 1 | 0 | 0 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat PQQ_3 (PF13570): PQQ-like domain BBS2_Mid (PF14783, IPR029429): Ciliary BBSome complex subunit 2, middle region WD40_like (PF17005, IPR031544): WD40-like domain zf-C2H2_aberr (PF17017, IPR031514): Aberrant zinc-finger |
168 |
ZRANB1 | interactor | 7 | 0.524 | 8.917 | Copper-fist (PF00649, IPR001083, SM01090): Copper fist DNA binding domain OTU (PF02338, IPR003323): OTU-like cysteine protease zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others |