1 |
AP2M1 | parental protein | 201 | 0.058 | 28132.648 | Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain |
2 |
AAK1 | interactor | 9 | 0.861 | 0.679 | eIF-3_zeta (PF05091, IPR007783): Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pkinase (PF00069, IPR000719): Protein kinase domain |
3 |
ABL1 | oncoprotein | 18 | 0.493 | 26.927 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding SH3_1 (PF00018, IPR001452, SM00326): SH3 domain FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2 |
4 |
ACACA | interactor | 4 | 0.833 | 0.065 | ACC_central (PF08326, IPR013537): Acetyl-CoA carboxylase, central region Biotin_carb_C (PF02785, IPR005482, SM00878): Biotin carboxylase C-terminal domain Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme Carboxyl_trans (PF01039, IPR000022): Carboxyl transferase domain Biotin_carb_N (PF00289, IPR005481): Biotin carboxylase, N-terminal domain CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain DUF445 (PF04286, IPR007383): Protein of unknown function (DUF445) |
5 |
ACTB | oncoprotein | 25 | 0.446 | 51.634 | Actin (PF00022, IPR004000, SM00268): Actin |
6 |
ADRA1B | interactor | 1 | 0 | 0 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) 7tm_4 (PF13853): Olfactory receptor Shisa (PF13908, IPR026910): Wnt and FGF inhibitory regulator |
7 |
AKAP11 | interactor | 3 | 0.667 | 0.667 | E_raikovi_mat (PF06360, IPR009064): Euplotes raikovi mating pheromone RNA_lig_T4_1 (PF09511, IPR019039): RNA ligase |
8 |
AMER1 | suppressor | 4 | 1.000 | 0 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region WTX (PF09422, IPR019003): WTX protein RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31 |
9 |
ANKRD28 | interactor | 5 | 0.500 | 3.500 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
10 |
ANKRD52 | interactor | 3 | 1.000 | 0 | Ank (PF00023, IPR002110, SM00248): Ankyrin repeat Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
11 |
ANLN | oncoprotein | 26 | 0.662 | 26.590 | Anillin (PF08174, IPR012966): Cell division protein anillin PH (PF00169, IPR001849, SM00233): PH domain Anillin_N (PF16018, IPR031970): Anillin N-terminus |
12 |
AP1B1 | interactor | 18 | 0.490 | 32.818 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain B2-adapt-app_C (PF09066, IPR015151, SM01020): Beta2-adaptin appendage, C-terminal sub-domain |
13 |
AP1G1 | interactor | 16 | 0.508 | 30.666 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain |
14 |
AP1G2 | interactor | 6 | 0.667 | 3.952 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain |
15 |
AP1S1 | interactor | 8 | 0.786 | 2.146 | Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain |
16 |
AP1S2 | interactor | 8 | 0.786 | 2.192 | Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain |
17 |
AP1S3 | interactor | 1 | 0 | 0 | Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain |
18 |
AP2A1 | interactor | 46 | 0.370 | 268.704 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region Alpha_adaptin_C (PF02296, IPR003164): Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain HEAT_2 (PF13646): HEAT repeats |
19 |
AP2A2 | interactor | 22 | 0.597 | 22.032 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region Alpha_adaptin_C (PF02296, IPR003164): Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain HEAT_2 (PF13646): HEAT repeats |
20 |
AP2B1 | interactor | 41 | 0.367 | 217.883 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain B2-adapt-app_C (PF09066, IPR015151, SM01020): Beta2-adaptin appendage, C-terminal sub-domain |
21 |
AP2S1 | interactor | 14 | 0.626 | 9.240 | Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain |
22 |
APC | suppressor | 18 | 0.228 | 68.175 | APC_15aa (PF05972, IPR009240): APC 15 residue motif APC_basic (PF05956, IPR009234): APC basic domain APC_r (PF05923): APC repeat Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) EB1_binding (PF05937, IPR009232): EB-1 Binding Domain FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) SAMP (PF05924, IPR009224): SAMP Motif Suppressor_APC (PF11414, IPR026831): Adenomatous polyposis coli tumour suppressor protein AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term SAS4 (PF15460, IPR029184): Something about silencing, SAS, complex subunit 4 Arm_APC_u3 (PF16629): Armadillo-associated region on APC APC_u5 (PF16630): Unstructured region on APC between 1st and 2nd catenin-bdg motifs APC_u9 (PF16633): Unstructured region on APC between 1st two creatine-rich regions APC_u13 (PF16634): Unstructured region on APC between APC_crr and SAMP APC_u14 (PF16635): Unstructured region on APC between SAMP and APC_crr APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6 APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain |
23 |
AQP4 | interactor | 1 | 0 | 0 | MIP (PF00230, IPR000425): Major intrinsic protein |
24 |
ARRB2 | interactor | 36 | 0.252 | 201.743 | Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain |
25 |
ATG16L1 | interactor | 6 | 0.500 | 1.295 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2332 (PF10094, IPR011200): Uncharacterized protein conserved in bacteria (DUF2332) Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 |
26 |
ATXN1L | interactor | 5 | 0.500 | 2.667 | AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH) |
27 |
ATXN2L | interactor | 5 | 0.700 | 0.554 | LsmAD (PF06741, IPR009604): LsmAD domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region SM-ATX (PF14438, IPR025852): Ataxin 2 SM domain |
28 |
BCR | suppressor | 8 | 0.857 | 0.562 | Bcr-Abl_Oligo (PF09036, IPR015123): Bcr-Abl oncoprotein oligomerisation domain C2 (PF00168, IPR000008, SM00239): C2 domain PH (PF00169, IPR001849, SM00233): PH domain RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain IQ_SEC7_PH (PF16453, IPR001849): PH domain |
29 |
BMP2K | interactor | 22 | 0.654 | 16.625 | Pkinase (PF00069, IPR000719): Protein kinase domain TCP (PF03634, IPR005333): TCP family transcription factor Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal EOS1 (PF12326, IPR021100): N-glycosylation protein BMP2K_C (PF15282, IPR028182): BMP-2-inducible protein kinase C-terminus PNRC (PF15365, IPR028322): Proline-rich nuclear receptor coactivator FAM60A (PF15396, IPR026065): Protein Family FAM60A |
30 |
C1orf226 | interactor | 1 | 0 | 0 | DUF4628 (PF15429, IPR027851): Domain of unknown function (DUF4628) |
31 |
CACNA1A | interactor | 2 | 1.000 | 0 | Ca_chan_IQ (PF08763, IPR014873, SM01062): Voltage gated calcium channel IQ domain GRP (PF07172, IPR010800): Glycine rich protein family Ion_trans (PF00520, IPR005821): Ion transport protein Roughex (PF06020, IPR009259): Drosophila roughex protein SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region GPHH (PF16905, IPR031649): Voltage-dependent L-type calcium channel, IQ-associated |
32 |
CALCOCO1 | interactor | 2 | 1.000 | 0 | CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31 |
33 |
CAPZA2 | interactor | 28 | 0.638 | 46.134 | F-actin_cap_A (PF01267, IPR002189): F-actin capping protein alpha subunit |
34 |
CD22 | interactor | 4 | 1.000 | 0 | C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
35 |
CDH1 | suppressor | 12 | 0.400 | 17.079 | Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like Cadherin (PF00028, IPR002126, SM00112): Cadherin domain |
36 |
CDH3 | interactor | 5 | 1.000 | 0 | Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like LSR (PF05624, IPR008664): Lipolysis stimulated receptor (LSR) DUF2207 (PF09972, IPR018702): Predicted membrane protein (DUF2207) Cadherin (PF00028, IPR002126, SM00112): Cadherin domain Cadherin_3 (PF16184): Cadherin-like |
37 |
CDK11B | oncoprotein | 5 | 0.667 | 0.952 | DDHD (PF02862, IPR004177, SM01127): DDHD domain DivIC (PF04977, IPR007060): Septum formation initiator Pkinase (PF00069, IPR000719): Protein kinase domain DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748) |
38 |
CHD8 | oncoprotein | 2 | 1.000 | 0 | BUD22 (PF09073, IPR015158): BUD22 CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain BRK (PF07533, IPR006576, SM00592): BRK domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain FAM176 (PF14851): FAM176 family Myb_DNA-bind_7 (PF15963): Myb DNA-binding like |
39 |
CLEC4M | interactor | 2 | 0 | 0 | Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain DUF2730 (PF10805, IPR020269): Protein of unknown function (DUF2730) |
40 |
CLINT1 | protein found in more fusions | 26 | 0.610 | 42.090 | ENTH (PF01417, IPR001026, SM00273): ENTH domain |
41 |
CLTB | interactor | 30 | 0.637 | 34.836 | Clathrin_lg_ch (PF01086, IPR000996): Clathrin light chain |
42 |
CLTC | oncoprotein | 48 | 0.347 | 329.941 | Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker Clathrin_propel (PF01394, IPR022365): Clathrin propeller repeat Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS Clathrin_H_link (PF13838): Clathrin-H-link |
43 |
COLEC12 | interactor | 1 | 0 | 0 | Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) Filament (PF00038, IPR001664): Intermediate filament protein Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5 Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain |
44 |
CORO1C | oncoprotein | 19 | 0.526 | 28.853 | DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat WD40_4 (PF16300): Type of WD40 repeat |
45 |
CORO7 | interactor | 4 | 0.833 | 0.667 | DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_4 (PF16300): Type of WD40 repeat |
46 |
CRK | oncoprotein | 44 | 0.224 | 343.206 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
47 |
CRY1 | interactor | 19 | 0.229 | 44.805 | DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase |
48 |
CRY2 | protein found in more fusions | 16 | 0.305 | 38.439 | DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase |
49 |
CSNK2B | interactor | 16 | 0.314 | 44.565 | CK_II_beta (PF01214, IPR000704, SM01085): Casein kinase II regulatory subunit |
50 |
CTLA4 | interactor | 2 | 0 | 0 | V-set (PF07686, IPR013106): Immunoglobulin V-set domain |
51 |
CTNNB1 | oncoprotein | 21 | 0.281 | 100.526 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat |
52 |
CTNND1 | suppressor | 8 | 0.643 | 4.362 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Ebp2 (PF05890, IPR008610): Eukaryotic rRNA processing protein EBP2 Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain |
53 |
CUL3 | protein found in more fusions | 58 | 0.136 | 863.604 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
54 |
DAB2 | suppressor | 29 | 0.512 | 77.604 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) zf-C2H2_assoc3 (PF16637): Putative zinc-finger between two C2H2 zinc-fingers on Patz |
55 |
DBN1 | oncoprotein | 32 | 0.617 | 39.344 | Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c |
56 |
DCAF1 | protein found in more fusions | 5 | 0.667 | 0.444 | DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) LisH (PF08513, IPR013720, SM00667): LisH ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated |
57 |
DDX3X | suppressor | 11 | 0.436 | 4.231 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
58 |
DDX47 | interactor | 4 | 1.000 | 0 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
59 |
DDX6 | oncoprotein | 10 | 0.311 | 23.037 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
60 |
DGKI | interactor | 1 | 0 | 0 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) DAGK_acc (PF00609, IPR000756, SM00045): Diacylglycerol kinase accessory domain DAGK_cat (PF00781, IPR001206, SM00046): Diacylglycerol kinase catalytic domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) |
61 |
DIEXF | interactor | 2 | 1.000 | 0 | UTP25 (PF06862, IPR010678): Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 eIF-3c_N (PF05470, IPR008905): Eukaryotic translation initiation factor 3 subunit 8 N-terminus SDA1 (PF05285, IPR007949): SDA1 |
62 |
DPPA2 | interactor | 4 | 0.667 | 0.667 | SAP (PF02037, IPR003034, SM00513): SAP domain DCR (PF14047, IPR025891): Dppa2/4 conserved region Dppa2_A (PF14049, IPR025892): Dppa2/4 conserved region in higher vertebrates |
63 |
DVL2 | interactor | 12 | 0.327 | 26.419 | DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Dishevelled (PF02377, IPR003351): Dishevelled specific domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DIX (PF00778, IPR001158, SM00021): DIX domain Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal |
64 |
EEF1A1 | suppressor | 23 | 0.429 | 47.622 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
65 |
EGFR | oncoprotein | 47 | 0.246 | 407.042 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
66 |
EHD2 | interactor | 3 | 1.000 | 0 | Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand EHD_N (PF16880, IPR031692): N-terminal EH-domain containing protein |
67 |
EPHA2 | suppressor | 11 | 0.778 | 3.015 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain |
68 |
EPN1 | interactor | 20 | 0.453 | 48.975 | ENTH (PF01417, IPR001026, SM00273): ENTH domain UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif |
69 |
EPS15 | oncoprotein | 67 | 0.234 | 928.737 | Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391) EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
70 |
EPS15L1 | oncoprotein | 8 | 0.357 | 8.360 | CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand |
71 |
ESR1 | suppressor | 33 | 0.272 | 159.624 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
72 |
FAM199X | interactor | 1 | 0 | 0 | FAM199X (PF15814, IPR029672): Protein family FAM199X |
73 |
FAM208A | interactor | 1 | 0 | 0 | DUF3715 (PF12509, IPR022188): Protein of unknown function (DUF3715) |
74 |
FASN | interactor | 11 | 0.267 | 7.087 | Acyl_transf_1 (PF00698, IPR014043): Acyl transferase domain ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase ketoacyl-synt (PF00109, IPR014030): Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C (PF02801, IPR014031): Beta-ketoacyl synthase, C-terminal domain KR (PF08659, IPR013968, SM00130): KR domain L27 (PF02828, IPR014775, SM00569): L27 domain Methyltransf_12 (PF08242, IPR013217): Methyltransferase domain PP-binding (PF00550, IPR009081): Phosphopantetheine attachment site Thioesterase (PF00975, IPR001031): Thioesterase domain YjeF_N (PF03853, IPR004443): YjeF-related protein N-terminus ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase PS-DH (PF14765, IPR020807): Polyketide synthase dehydratase KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension |
75 |
FCHO2 | protein found in more fusions | 14 | 0.813 | 3.062 | DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain PIN_2 (PF10130, IPR002716): PIN domain muHD (PF10291, IPR018808): Muniscin C-terminal mu homology domain |
76 |
FLNA | suppressor | 35 | 0.491 | 97.609 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Filamin (PF00630, IPR017868): Filamin/ABP280 repeat |
77 |
FN1 | oncoprotein | 54 | 0.213 | 491.054 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
78 |
FURIN | interactor | 1 | 0 | 0 | DUF357 (PF04010, IPR023140): Protein of unknown function (DUF357) P_proprotein (PF01483, IPR002884): Proprotein convertase P-domain Peptidase_S8 (PF00082, IPR000209): Subtilase family VSP (PF03302, IPR005127): Giardia variant-specific surface protein Furin-like_2 (PF15913, IPR006212): Furin-like repeat, cysteine-rich S8_pro-domain (PF16470, IPR032815): Peptidase S8 pro-domain |
79 |
FXR2 | interactor | 5 | 0.500 | 2.333 | Agenet (PF05641, IPR008395, SM00743): Agenet domain REV (PF00424, IPR000625): REV protein (anti-repression trans-activator protein) KH_1 (PF00013, IPR004088, SM00322): KH domain FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2 |
80 |
GAK | oncoprotein | 18 | 0.745 | 7.129 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain Pkinase (PF00069, IPR000719): Protein kinase domain PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein |
81 |
GAPDH | oncoprotein | 18 | 0.610 | 9.266 | Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain OstA (PF03968, IPR005653): OstA-like protein |
82 |
GFAP | protein found in more fusions | 5 | 0.667 | 0.472 | Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region |
83 |
GLP1R | interactor | 1 | 0 | 0 | 7tm_2 (PF00002, IPR000832): 7 transmembrane receptor (Secretin family) HRM (PF02793, IPR001879, SM00008): Hormone receptor domain |
84 |
GRB2 | oncoprotein | 54 | 0.257 | 488.796 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093) |
85 |
GTSE1 | interactor | 34 | 0.433 | 150.049 | GTSE1_N (PF15259, IPR032768): G-2 and S-phase expressed 1 |
86 |
GULP1 | interactor | 1 | 0 | 0 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper |
87 |
HAT1 | interactor | 4 | 0.833 | 0.200 | Hat1_N (PF10394, IPR019467): Histone acetyl transferase HAT1 N-terminus Acetyltransf_7 (PF13508, IPR000182): Acetyltransferase (GNAT) domain Acetyltransf_10 (PF13673, IPR000182): Acetyltransferase (GNAT) domain |
88 |
HNRNPA2B1 | oncoprotein | 15 | 0.476 | 14.636 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
89 |
HSPA1A | interactor | 19 | 0.409 | 44.102 | HSP70 (PF00012, IPR013126): Hsp70 protein |
90 |
HSPA1B | interactor | 15 | 0.381 | 10.913 | HSP70 (PF00012, IPR013126): Hsp70 protein |
91 |
HSPA1L | interactor | 14 | 0.505 | 10.069 | HSP70 (PF00012, IPR013126): Hsp70 protein |
92 |
HSPA6 | interactor | 7 | 0.762 | 0.844 | HSP70 (PF00012, IPR013126): Hsp70 protein |
93 |
HSPA8 | oncoprotein | 30 | 0.384 | 109.590 | HSP70 (PF00012, IPR013126): Hsp70 protein |
94 |
HSPA9 | oncoprotein | 17 | 0.493 | 28.143 | HSP70 (PF00012, IPR013126): Hsp70 protein |
95 |
IFNAR1 | oncoprotein | 1 | 0 | 0 | Interfer-bind (PF09294, IPR015373): Interferon-alpha/beta receptor, fibronectin type III Tissue_fac (PF01108, IPR003961): Tissue factor |
96 |
IKZF1 | suppressor | 4 | 0.667 | 1.000 | Desulfoferrod_N (PF06397, IPR004462): Desulfoferrodoxin, N-terminal domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-met (PF12874): Zinc-finger of C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |
97 |
INTU | interactor | 1 | 0 | 0 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) |
98 |
IQGAP1 | interactor | 34 | 0.444 | 146.428 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF87 (PF01935, IPR002789): Domain of unknown function DUF87 IDEAL (PF08858, IPR014957, SM00914): IDEAL domain IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase RasGAP_C (PF03836, IPR000593): RasGAP C-terminus WW (PF00397, IPR001202, SM00456): WW domain |
99 |
ITGA4 | interactor | 41 | 0.269 | 201.920 | FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha |
100 |
ITSN1 | interactor | 15 | 0.374 | 28.487 | C2 (PF00168, IPR000008, SM00239): C2 domain VIT1 (PF01988, IPR008217): VIT family DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) FmdE (PF02663, IPR003814): FmdE, Molybdenum formylmethanofuran dehydrogenase operon GSH_synthase (PF03199, IPR004887): Eukaryotic glutathione synthase RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) SH3_9 (PF14604, IPR001452): Variant SH3 domain DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748) INTAP (PF16617): Intersectin and clathrin adaptor AP2 binding region PH_13 (PF16652, IPR001849): Pleckstrin homology domain |
101 |
ITSN2 | protein found in more fusions | 7 | 0.600 | 2.638 | C2 (PF00168, IPR000008, SM00239): C2 domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) SH3_9 (PF14604, IPR001452): Variant SH3 domain MRP-S26 (PF14943, IPR026140): Mitochondrial ribosome subunit S26 VIR_N (PF15912, IPR031801): Virilizer, N-terminal PH_13 (PF16652, IPR001849): Pleckstrin homology domain |
102 |
KBTBD6 | interactor | 3 | 1.000 | 0 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_4 (PF13418): Galactose oxidase, central domain Kelch_6 (PF13964): Kelch motif |
103 |
KBTBD7 | interactor | 4 | 0.667 | 1.200 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_2 (PF07646, IPR011498): Kelch motif Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_4 (PF13418): Galactose oxidase, central domain Kelch_6 (PF13964): Kelch motif |
104 |
KCNQ1 | interactor | 1 | 0 | 0 | Ion_trans (PF00520, IPR005821): Ion transport protein KCNQ_channel (PF03520, IPR013821): KCNQ voltage-gated potassium channel Sensor (PF13796, IPR025828): Putative sensor |
105 |
KIAA0232 | interactor | 1 | 0 | 0 | DUF4603 (PF15376, IPR027871): Domain of unknown function (DUF4603) |
106 |
KIF13A | interactor | 3 | 1.000 | 0 | FHA (PF00498, IPR000253, SM00240): FHA domain Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain KIF1B (PF12423, IPR022140): Kinesin protein 1B DUF3694 (PF12473, IPR022164): Kinesin protein DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) FAM184 (PF15665): Family with sequence similarity 184, A and B Kinesin_assoc (PF16183, IPR032405): Kinesin-associated |
107 |
KRT1 | interactor | 17 | 0.551 | 20.917 | Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region Keratin_2_head (PF16208, IPR032444): Keratin type II head Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail |
108 |
KRT10 | interactor | 16 | 0.575 | 13.688 | Filament (PF00038, IPR001664): Intermediate filament protein FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
109 |
KRT14 | interactor | 9 | 0.667 | 3.229 | Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region Keratin_2_head (PF16208, IPR032444): Keratin type II head |
110 |
KRT16 | interactor | 10 | 0.756 | 1.074 | Filament (PF00038, IPR001664): Intermediate filament protein zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein Keratin_2_head (PF16208, IPR032444): Keratin type II head |
111 |
KRT17 | interactor | 7 | 0.714 | 2.077 | DUF1798 (PF08807, IPR014913): Bacterial domain of unknown function (DUF1798) Filament (PF00038, IPR001664): Intermediate filament protein |
112 |
KRT2 | interactor | 13 | 0.641 | 6.958 | Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head |
113 |
KRT3 | interactor | 6 | 0.933 | 0.069 | Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head |
114 |
KRT5 | interactor | 14 | 0.648 | 12.024 | Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head |
115 |
KRT6A | interactor | 7 | 0.810 | 0.759 | Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head |
116 |
KRT6B | interactor | 3 | 0.667 | 0.071 | Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head |
117 |
KRT73 | oncoprotein | 4 | 1.000 | 0 | Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head |
118 |
KRT77 | interactor | 6 | 1.000 | 0 | Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail |
119 |
KRT79 | interactor | 3 | 1.000 | 0 | Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head |
120 |
KRT9 | interactor | 11 | 0.600 | 3.580 | Filament (PF00038, IPR001664): Intermediate filament protein FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
121 |
LIMA1 | suppressor | 30 | 0.630 | 34.642 | LIM (PF00412, IPR001781, SM00132): LIM domain ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain |
122 |
LY9 | interactor | 1 | 0 | 0 | ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
123 |
MAGEC2 | interactor | 1 | 0 | 0 | MAGE (PF01454, IPR002190): MAGE family MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal APOC4 (PF15119, IPR028120): Apolipoprotein C4 |
124 |
MAGED4B | interactor | 1 | 0 | 0 | MAGE (PF01454, IPR002190): MAGE family Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein DUF3123 (PF11321, IPR021470): Protein of unknown function (DUF3123) |
125 |
MAP4 | oncoprotein | 5 | 0.700 | 1.082 | SdiA-regulated (PF06977, IPR009722): SdiA-regulated Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat DUF3275 (PF11679, IPR021693): Protein of unknown function (DUF3275) |
126 |
MARK2 | protein found in more fusions | 5 | 0.500 | 2.333 | DUF702 (PF05142, IPR007818): Domain of unknown function (DUF702) KA1 (PF02149, IPR001772): Kinase associated domain 1 Pkinase (PF00069, IPR000719): Protein kinase domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain |
127 |
MASP1 | interactor | 2 | 1.000 | 0 | CUB (PF00431, IPR000859, SM00042): CUB domain Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat) Trypsin (PF00089, IPR001254, SM00020): Trypsin FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site |
128 |
MEA1 | interactor | 2 | 1.000 | 0 | MEA1 (PF06910, IPR009685): Male enhanced antigen 1 (MEA1) |
129 |
MED4 | interactor | 7 | 0.381 | 6.085 | Med4 (PF10018, IPR019258): Vitamin-D-receptor interacting Mediator subunit 4 |
130 |
MEGF10 | interactor | 1 | 0 | 0 | DSL (PF01414, IPR001774, SM00051): Delta serrate ligand EGF_2 (PF07974, IPR013111): EGF-like domain Syndecan (PF01034, IPR027789): Syndecan domain Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like |
131 |
MRPL58 | interactor | 5 | 0.500 | 3.333 | RF-1 (PF00472, IPR000352): RF-1 domain |
132 |
MYH9 | suppressor | 37 | 0.505 | 123.274 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
133 |
MYO18A | interactor | 24 | 0.678 | 33.234 | Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_tail_1 (PF01576, IPR002928): Myosin tail PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 |
134 |
MYO19 | interactor | 26 | 0.695 | 27.295 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
135 |
NAGPA | interactor | 3 | 1.000 | 0 | EGF_2 (PF07974, IPR013111): EGF-like domain NAGPA (PF09992, IPR018711): Phosphodiester glycosidase |
136 |
NCOR2 | oncoprotein | 4 | 0.500 | 3.000 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal MAS20 (PF02064, IPR002056): MAS20 protein import receptor OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK) SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Gti1_Pac2 (PF09729, IPR018608): Gti1/Pac2 family PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Spt20 (PF12090, IPR021950): Spt20 family DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4518 (PF15008, IPR026698): Domain of unknown function (DUF4518) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820) |
137 |
NDRG1 | suppressor | 8 | 0.393 | 8.888 | Ndr (PF03096, IPR004142): Ndr family |
138 |
NECAP1 | interactor | 6 | 0.867 | 0.450 | DUF1681 (PF07933, IPR012466): Protein of unknown function (DUF1681) |
139 |
NECAP2 | interactor | 13 | 0.500 | 19.431 | DUF1681 (PF07933, IPR012466): Protein of unknown function (DUF1681) |
140 |
NKAP | interactor | 3 | 1.000 | 0 | SynMuv_product (PF06047, IPR009269): Ras-induced vulval development antagonist Pheromone (PF08015, IPR012597): Fungal mating-type pheromone SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein NKAP (PF15692): NF-kappa-B-activating protein |
141 |
NOS1AP | interactor | 3 | 0.667 | 1.000 | Phage_GPO (PF05929, IPR009228): Phage capsid scaffolding protein (GPO) serine peptidase PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) |
142 |
NUMB | suppressor | 13 | 0.692 | 6.588 | NumbF (PF06311, IPR010449): NUMB domain PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) |
143 |
OTUD6B | interactor | 2 | 1.000 | 0 | Cep57_MT_bd (PF06657, IPR024957): Centrosome microtubule-binding domain of Cep57 Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family HemY_N (PF07219, IPR010817): HemY protein N-terminus OTU (PF02338, IPR003323): OTU-like cysteine protease DUF2335 (PF10097, IPR019284): Predicted membrane protein (DUF2335) |
144 |
PDLIM7 | interactor | 15 | 0.667 | 13.489 | LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749) |
145 |
PER1 | oncoprotein | 7 | 0.619 | 5.167 | PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold SPX (PF03105, IPR004331): SPX domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Period_C (PF12114, IPR022728): Period protein 2/3C-terminal region |
146 |
PEX14 | protein found in more fusions | 9 | 0.500 | 7.355 | HemX (PF04375, IPR007470): HemX, putative uroporphyrinogen-III C-methyltransferase Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation |
147 |
PEX5 | interactor | 4 | 0.500 | 1.178 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat SHNi-TPR (PF10516, IPR019544): SHNi-TPR TPR_12 (PF13424): Tetratricopeptide repeat TPR_15 (PF13429): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
148 |
PICALM | oncoprotein | 28 | 0.601 | 38.609 | ANTH (PF07651, IPR011417): ANTH domain |
149 |
PJA1 | interactor | 5 | 0.500 | 0.633 | zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain |
150 |
PJA2 | protein found in more fusions | 4 | 0.667 | 0.100 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain |
151 |
PLRG1 | interactor | 3 | 0.667 | 0.100 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
152 |
PPHLN1 | interactor | 1 | 0 | 0 | Lge1 (PF11488): Transcriptional regulatory protein LGE1 HERV-K_REC (PF15695): Rec (regulator of expression encoded by corf) of HERV-K-113 |
153 |
PPP6R2 | interactor | 6 | 0.467 | 5.543 | SAMP (PF05924, IPR009224): SAMP Motif SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein |
154 |
PRKACB | interactor | 5 | 0.600 | 3.333 | Pkinase (PF00069, IPR000719): Protein kinase domain |
155 |
PRKAR1B | interactor | 6 | 0.600 | 1.520 | RIIa (PF02197, IPR003117, SM00394): Regulatory subunit of type II PKA R-subunit cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain |
156 |
PRKDC | protein found in more fusions | 17 | 0.325 | 30.333 | FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain NUC194 (PF08163, IPR012582): NUC194 domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase |
157 |
RAB7A | suppressor | 6 | 0.600 | 2.173 | Ras (PF00071, IPR001806, SM00173): Ras family |
158 |
RALBP1 | interactor | 7 | 0.714 | 2.165 | DDHD (PF02862, IPR004177, SM01127): DDHD domain RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain SlyX (PF04102, IPR007236): SlyX Vps39_2 (PF10367, IPR019453): Vacuolar sorting protein 39 domain 2 DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968) DUF3505 (PF12013, IPR022698): Protein of unknown function (DUF3505) Nod1 (PF17114, IPR032634): Gef2-related medial cortical node protein Nod1 |
159 |
RALGAPA1 | interactor | 1 | 0 | 0 | Rap_GAP (PF02145, IPR000331): Rap/ran-GAP |
160 |
REPS1 | protein found in more fusions | 9 | 0.429 | 7.458 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator MCLC (PF05934, IPR009231): Mid-1-related chloride channel (MCLC) DUF3123 (PF11321, IPR021470): Protein of unknown function (DUF3123) EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand |
161 |
REXO1 | interactor | 1 | 0 | 0 | TIL (PF01826, IPR002919): Trypsin Inhibitor like cysteine rich domain RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein EloA-BP1 (PF15870, IPR031736): ElonginA binding-protein 1 |
162 |
RNF11 | protein found in more fusions | 10 | 0.528 | 4.988 | zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-ANAPC11 (PF12861, IPR024991): Anaphase-promoting complex subunit 11 RING-H2 finger |
163 |
RPL38 | interactor | 6 | 0.533 | 0.904 | Ribosomal_L38e (PF01781, IPR002675): Ribosomal L38e protein family |
164 |
RPS27A | interactor | 10 | 0.422 | 10.407 | DUF1049 (PF06305, IPR010445): Protein of unknown function (DUF1049) |
165 |
RRP12 | interactor | 3 | 1.000 | 0 | NUC173 (PF08161, IPR012978): NUC173 domain PGA2 (PF07543, IPR011431): Protein trafficking PGA2 PPP4R2 (PF09184, IPR015267): PPP4R2 Ribosomal_L37 (PF08561, IPR013870): Mitochondrial ribosomal protein L37 DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal |
166 |
RSPH14 | interactor | 1 | 0 | 0 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat HEAT (PF02985, IPR000357): HEAT repeat Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 |
167 |
RUNDC3A | interactor | 2 | 1.000 | 0 | Phage_GP20 (PF06810, IPR009636): Phage minor structural protein GP20 RUN (PF02759, IPR004012, SM00593): RUN domain |
168 |
RUVBL2 | oncoprotein | 18 | 0.375 | 35.459 | TIP49 (PF06068, IPR010339): TIP49 C-terminus |
169 |
SERPINB12 | interactor | 1 | 0 | 0 | Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor) |
170 |
SFPQ | oncoprotein | 12 | 0.509 | 4.839 | GRP (PF07172, IPR010800): Glycine rich protein family Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1 CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance |
171 |
SHC1 | oncoprotein | 50 | 0.197 | 429.413 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) SH2 (PF00017, IPR000980, SM00252): SH2 domain |
172 |
SLC25A4 | interactor | 4 | 0.667 | 1.286 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
173 |
SLC25A41 | interactor | 13 | 0.397 | 17.598 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
174 |
SLC25A5 | interactor | 12 | 0.424 | 18.811 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
175 |
SLC25A6 | interactor | 6 | 0.533 | 4.500 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
176 |
SNX29 | oncoprotein | 1 | 0 | 0 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor PX (PF00787, IPR001683, SM00312): PX domain RUN (PF02759, IPR004012, SM00593): RUN domain TSC22 (PF01166, IPR000580): TSC-22/dip/bun family UPF0054 (PF02130, IPR002036): Uncharacterized protein family UPF0054 NYD-SP28 (PF14772): Sperm tail |
177 |
SPECC1L | interactor | 13 | 0.577 | 10.995 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding KASH_CCD (PF14662, IPR028168): Coiled-coil region of CCDC155 or KASH Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease DUF4763 (PF15960, IPR031883): Domain of unknown function (DUF4763) |
178 |
SPTBN1 | suppressor | 20 | 0.505 | 31.056 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2 DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Spectrin (PF00435, IPR002017): Spectrin repeat PH_9 (PF15410): Pleckstrin homology domain |
179 |
STAU1 | protein found in more fusions | 26 | 0.307 | 57.643 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain |
180 |
STK11 | suppressor | 5 | 0.500 | 3.917 | Pkinase (PF00069, IPR000719): Protein kinase domain |
181 |
STON2 | interactor | 23 | 0.557 | 34.647 | Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family Stonin2_N (PF12016, IPR022699): Stonin 2 |
182 |
STX8 | interactor | 1 | 0 | 0 | CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding SNARE (PF05739, IPR000727, SM00397): SNARE domain HD_assoc (PF13286, IPR026875): Phosphohydrolase-associated domain |
183 |
SV2A | interactor | 1 | 0 | 0 | MFS_1 (PF07690, IPR011701): Major Facilitator Superfamily Sugar_tr (PF00083, IPR005828): Sugar (and other) transporter Pentapeptide_4 (PF13599, IPR001646): Pentapeptide repeats (9 copies) |
184 |
SYNJ1 | interactor | 6 | 0.733 | 0.940 | DUF1866 (PF08952, IPR015047, SM01165): Domain of unknown function (DUF1866) Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family Syja_N (PF02383, IPR002013): SacI homology domain YppG (PF14179, IPR025555): YppG-like protein |
185 |
SYNPO | interactor | 25 | 0.683 | 22.352 | Calsarcin (PF05556, IPR008438): Calcineurin-binding protein (Calsarcin) |
186 |
TBC1D5 | interactor | 2 | 1.000 | 0 | RabGAP-TBC (PF00566, IPR000195, SM00164): Rab-GTPase-TBC domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452) |
187 |
TGOLN2 | interactor | 1 | 0 | 0 | MSA_2 (PF00985, IPR001136): Merozoite Surface Antigen 2 (MSA-2) family UCR_TM (PF02921, IPR004192): Ubiquinol cytochrome reductase transmembrane region SbcCD_C (PF13558): Putative exonuclease SbcCD, C subunit TUTF7_u4 (PF16631): Unstructured region 4 on terminal uridylyltransferase 7 |
188 |
TNKS2 | interactor | 2 | 0 | 0 | Ank (PF00023, IPR002110, SM00248): Ankyrin repeat PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
189 |
TSSC4 | suppressor | 1 | 0 | 0 | TSSC4 (PF15264, IPR029338): Tumour suppressing sub-chromosomal transferable candidate 4 |
190 |
TUBA1A | oncoprotein | 19 | 0.497 | 35.330 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
191 |
TUBA1B | interactor | 12 | 0.561 | 11.078 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
192 |
TUBA1C | interactor | 17 | 0.537 | 17.107 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
193 |
TUBA4B | interactor | 9 | 0.889 | 0.461 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain |
194 |
TUBB | interactor | 24 | 0.496 | 42.005 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
195 |
TUBB2A | interactor | 12 | 0.636 | 5.571 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
196 |
TUBB3 | interactor | 12 | 0.561 | 6.697 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
197 |
TUBB4B | interactor | 19 | 0.503 | 31.817 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
198 |
UBC | protein found in more fusions | 27 | 0.292 | 121.573 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
199 |
VCAM1 | interactor | 42 | 0.231 | 228.467 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
200 |
XPO1 | interactor | 62 | 0.144 | 1143.730 | CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region |
201 |
ZBTB8A | interactor | 5 | 0.500 | 2.000 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger |