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Visible interactions: all affected independent (normal) missing (in fusions) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)115
The number (and %) of the onco-proteins50 (43.48 %)
The number (and %) of the tumor suppressors19 (16.52 %)
Total number of binary PPIs (saturation %)746 (11.38 %)
The number (and %) of affected PPIs125 (16.76 %)
The number of possible different fusions39
PPI diameter3
PPI radius2
The average degree of PPI12.209
Assortativity coefficient-0.2107
The network average Clustering coefficient0.450
The number (and %) of a zero Clustering coefficients12 (10.43 %)
The number (and %) of a zero Betweenness Centrality19 (16.52 %)

ACTIVE INTERACTORS
MISSING INTERACTORS (in fusions)


List of the fusions

PPI for parental proteins: AFF1,KMT2A All fusions
: DQ451148; AJ430604; KT444631; AM949711; AM050752; AF397907; AM949686; AM050762; AF487905; AM050799; AF024541; JN169752; AF177237; AM949749; AM949740; AF492832; AM949687; AM949713; KT444632; AM050802; AM949733; AM050772; KT444629; KT444630; AM050766; AF177238; AF031404; AM050754; AF487906; AM949750; AM050744; AM050775; AM949753; AM050758; L22179; KT444628; AF492831; AF177239; AM949703; FM177515; AM050795; AF177236;
Proteins found in more fusions AFF1 (see 7 fusions); RELA (see 1 fusions); CTBP1 (see 3 fusions); KMT2A/AFDN (see 7 fusions); HDAC1 (see 5 fusions); NPM1 (see 7 fusions); KRAS (see 3 fusions); TBP (see 4 fusions); AFF1/KMT2A (see 182 fusions); HDAC2 (see 1 fusions); MLLT10 (see 1 fusions); SMARCB1 (see 14 fusions); RUNX1 (see 5 fusions); CREBBP (see 9 fusions); SMAD9 (see 3 fusions); CREBBP/KAT6A (see 9 fusions); EWSR1 (see 4 fusions); KIF11 (see 1 fusions); KMT2A (see 17 fusions); KAT8 (see 3 fusions); LGR4 (see 1 fusions); KMT2A/ELL (see 10 fusions); ASB2 (see 1 fusions); POLR2A (see 5 fusions); CHD3 (see 4 fusions); SIAH2 (see 2 fusions); SMARCC1 (see 5 fusions); HCFC1 (see 3 fusions); MAP3K5 (see 1 fusions); ASH2L (see 3 fusions); KMT2A/MLLT3 (see 22 fusions); RUNX1/SIN3A (see 1 fusions); KMT2A/MLLT1 (see 19 fusions); SET (see 6 fusions); NCL (see 13 fusions); TP53 (see 3 fusions); SNW1 (see 2 fusions); CDK9 (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 AFF1parental protein320.1761836.505AF-4 (PF05110, IPR007797): AF-4 proto-oncoprotein
2 KMT2Aparental protein940.1096422.656AT_hook (PF02178, IPR017956, SM00384): AT hook motif
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus
FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus
Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
SET (PF00856, IPR001214, SM00317): SET domain
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
3 AFDNoncoprotein40.5001.542DIL (PF01843, IPR018444, SM01132): DIL domain
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
FHA (PF00498, IPR000253, SM00240): FHA domain
MAP7 (PF05672, IPR008604): MAP7 (E-MAP-115) family
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
Pap_E4 (PF02711, IPR003861): E4 protein
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
ARGLU (PF15346): Arginine and glutamate-rich 1
4 AFF4oncoprotein150.53394.330AF-4 (PF05110, IPR007797): AF-4 proto-oncoprotein
5 ASB2protein found in more fusions80.33335.038Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
SOCS_box (PF07525, IPR001496): SOCS box
6 ASH2Lprotein found in more fusions180.39097.923SPRY (PF00622, IPR003877, SM00449): SPRY domain
PHD20L1_u1 (PF16660): PHD finger protein 20-like protein 1
7 AVPinteractor200Protamine_P1 (PF00260, IPR000221): Protamine P1
8 BMI1oncoprotein180.41247.131zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
9 BRD4oncoprotein90.33341.510Caldesmon (PF02029, IPR006018): Caldesmon
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
Stm1_N (PF09598, IPR019084): Stm1
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
NAM-associated (PF14303, IPR029466): No apical meristem-associated C-terminal domain
BET (PF17035, IPR027353): Bromodomain extra-terminal - transcription regulation
BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4
10 CARM1oncoprotein130.23172.630K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
CBP_GIL (PF10995, IPR017745): GGDEF I-site like or GIL domain
CARM1 (PF11531, IPR020989): Coactivator-associated arginine methyltransferase 1 N terminal
11 CBFBsuppressor40.6672.422CBF_beta (PF02312, IPR003417): Core binding factor beta subunit
12 CBX4oncoprotein120.40020.854Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
CBX7_C (PF17218): CBX family C-terminal motif
13 CBX8interactor110.57815.968Atrophin-1 (PF03154, IPR002951): Atrophin-1 family
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
RBR (PF17208): RNA binding Region
CBX7_C (PF17218): CBX family C-terminal motif
14 CCNT1oncoprotein180.419118.959Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region
CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit
MDFI (PF15316, IPR026134): MyoD family inhibitor
15 CDC73suppressor140.41841.889CDC73_C (PF05179, IPR007852): RNA pol II accessory factor, Cdc73 family, C-terminal
CDC73_N (PF16050, IPR032041): Paf1 complex subunit CDC73 N-terminal
16 CDK9protein found in more fusions220.381193.994Pkinase (PF00069, IPR000719): Protein kinase domain
17 CHD3oncoprotein190.52334.265CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086)
DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087)
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF2956 (PF11169, IPR021339): Protein of unknown function (DUF2956)
FAM176 (PF14851): FAM176 family
18 CREBBPsuppressor260.360110.447Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
19 CSNK2A2interactor120.30334.656Pkinase (PF00069, IPR000719): Protein kinase domain
20 CTBP1protein found in more fusions140.50020.6172-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D
21 CTNNB1oncoprotein110.38243.931Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
22 CTR9interactor160.350118.773DUF702 (PF05142, IPR007818): Domain of unknown function (DUF702)
Pap_E4 (PF02711, IPR003861): E4 protein
SPT16 (PF08644, IPR013953): FACT complex subunit (SPT16/CDC68)
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
DUF2175 (PF09943, IPR018686): Uncharacterized protein conserved in archaea (DUF2175)
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
23 CXXC1interactor100.6009.819ATP-synt_E (PF05680, IPR008386): ATP synthase E chain
PHD (PF00628, IPR019787, SM00249): PHD-finger
PLATZ (PF04640, IPR006734): PLATZ transcription factor
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
DUF2116 (PF09889, IPR019216): Uncharacterized protein containing a Zn-ribbon (DUF2116)
Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
DUF3347 (PF11827, IPR021782): Protein of unknown function (DUF3347)
zf-CpG_bind_C (PF12269, IPR022056): CpG binding protein zinc finger C terminal domain
24 DDX6oncoprotein100DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
25 DOT1Loncoprotein90.47245.474AT_hook (PF02178, IPR017956, SM00384): AT hook motif
DivIC (PF04977, IPR007060): Septum formation initiator
DOT1 (PF08123, IPR013110): Histone methylation protein DOT1
ZapB (PF06005, IPR009252): Cell division protein ZapB
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
TraV (PF09676, IPR014118): Type IV conjugative transfer system lipoprotein (TraV)
26 DYNLT1interactor30.6671.000Tctex-1 (PF03645, IPR005334): Tctex-1 family
27 E2F2suppressor100E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain
E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
28 E2F4suppressor50.8000.736E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain
Pheromone (PF08015, IPR012597): Fungal mating-type pheromone
SPX (PF03105, IPR004331): SPX domain
DUF3584 (PF12128, IPR021979): Protein of unknown function (DUF3584)
E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
29 E2F6oncoprotein60.8001.057BRCA-2_OB3 (PF09104, IPR015188): BRCA2, oligonucleotide/oligosaccharide-binding, domain 3
E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain
E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
30 EAF1suppressor100.68918.580Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Peroxin-3 (PF04882, IPR006966): Peroxin-3
EAF (PF09816, IPR019194): RNA polymerase II transcription elongation factor
31 ELLoncoprotein100.64432.243Occludin_ELL (PF07303, IPR010844): Occludin homology domain
ELL (PF10390, IPR019464): RNA polymerase II elongation factor ELL
32 ELL2interactor100.71112.220Occludin_ELL (PF07303, IPR010844): Occludin homology domain
Wbp11 (PF09429, IPR019007): WW domain binding protein 11
ELL (PF10390, IPR019464): RNA polymerase II elongation factor ELL
33 ELL3interactor80.6797.980Occludin_ELL (PF07303, IPR010844): Occludin homology domain
ELL (PF10390, IPR019464): RNA polymerase II elongation factor ELL
TEX19 (PF15553, IPR029093): Testis-expressed protein 19
34 ELOBinteractor60.6005.354ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
35 ELOConcoprotein60.6005.021Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain
36 EWSR1oncoprotein150.40740.756RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
37 H2BC8oncoprotein50.5002.881Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
38 H3-3Aoncoprotein120.30342.267Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
39 H3-4interactor300.264312.166Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
40 H3C1interactor290.246247.606Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
41 H3C14interactor80.28623.788Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
42 H4C1interactor150.42954.595CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
43 HCFC1protein found in more fusions170.42543.956fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
zf-tcix (PF14952, IPR029269): Putative treble-clef, zinc-finger, Zn-binding
44 HCFC2interactor61.0000fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
45 HDAC1suppressor350.333376.018FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
46 HDAC2suppressor280.46472.243Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
47 HECW2interactor100.47213.532C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
RFXA_RFXANK_bdg (PF15289, IPR029316): Regulatory factor X-associated C-terminal binding domain
HECW_N (PF16562, IPR032348): N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2
48 HEXIM1oncoprotein100.46724.309APG6 (PF04111, IPR007243): Autophagy protein Apg6
DivIC (PF04977, IPR007060): Septum formation initiator
Shugoshin_N (PF07558, IPR011516): Shugoshin N-terminal coiled-coil region
HEXIM (PF15313, IPR024872): Hexamethylene bis-acetamide-inducible protein
49 ING4suppressor70.3336.639PHD (PF00628, IPR019787, SM00249): PHD-finger
SOGA (PF11365, IPR027881): Protein SOGA
ING (PF12998, IPR024610): Inhibitor of growth proteins N-terminal histone-binding
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
50 INSinteractor100Insulin (PF00049, IPR016179, SM00078): Insulin/IGF/Relaxin family
51 KAT6Aoncoprotein100.42216.468BUD22 (PF09073, IPR015158): BUD22
MOZ_SAS (PF01853, IPR002717): MOZ/SAS family
PHD (PF00628, IPR019787, SM00249): PHD-finger
Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
zf-met (PF12874): Zinc-finger of C2H2 type
52 KAT8protein found in more fusions130.36440.126MOZ_SAS (PF01853, IPR002717): MOZ/SAS family
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
53 KIF11protein found in more fusions60.4003.641Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2
DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
Gag_p17 (PF00540, IPR000071): gag gene protein p17 (matrix protein)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
DUF3510 (PF12022, IPR024603): Domain of unknown function (DUF3510)
Microtub_bind (PF13931, IPR025901): Kinesin-associated microtubule-binding
54 KRASoncoprotein80.28615.150Ras (PF00071, IPR001806, SM00173): Ras family
55 LARP7interactor70.4299.885Agouti (PF05039, IPR007733, SM00792): Agouti protein
DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
La (PF05383, IPR006630, SM00715): La domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RRM_3 (PF08777, IPR014886): RNA binding motif
56 LEO1interactor90.6677.387Leo1 (PF04004, IPR007149): Leo1-like protein
PPP4R2 (PF09184, IPR015267): PPP4R2
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
57 LGR4protein found in more fusions60.3006.0757tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
58 MAP3K5oncoprotein40.3339.125Pkinase (PF00069, IPR000719): Protein kinase domain
DUF4071 (PF13281, IPR025136): Domain of unknown function (DUF4071)
59 MBD3interactor120.8182.554DUF2201_N (PF13203, IPR025154): Putative metallopeptidase domain
60 MED26interactor150.42976.549Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain
Med26_C (PF15693, IPR031416): Mediator complex subunit 26 C-terminal
Med26_M (PF15694, IPR031417): Mediator complex subunit 26 middle domain
61 MEN1suppressor230.332115.862Menin (PF05053, IPR007747): Menin
62 MLLT1oncoprotein210.376210.674DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
Peptidase_S64 (PF08192, IPR012985): Peptidase family S64
YEATS (PF03366, IPR005033): YEATS family
DDRGK (PF09756, IPR019153, SM01128): DDRGK domain
63 MLLT10oncoprotein70.46720.574SpoIIIAH (PF12685, IPR024232): SpoIIIAH-like protein
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
PHD_2 (PF13831): PHD-finger
zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain
Tnp_zf-ribbon_2 (PF13842, IPR032718): DDE_Tnp_1-like zinc-ribbon
CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106
DUF4718 (PF15842, IPR031695): Domain of unknown function (DUF4718)
DUF4887 (PF16228, IPR032615): Domain of unknown function (DUF4887)
AP3D1 (PF06375): AP-3 complex subunit delta-1
64 MLLT3oncoprotein160.475112.432Peptidase_S64 (PF08192, IPR012985): Peptidase family S64
YEATS (PF03366, IPR005033): YEATS family
DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446)
Sox_N (PF12444, IPR022151): Sox developmental protein N terminal
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
NKAP (PF15692): NF-kappa-B-activating protein
BET (PF17035, IPR027353): Bromodomain extra-terminal - transcription regulation
65 MTM1interactor100GRAM (PF02893, IPR004182, SM00568): GRAM domain
Myotub-related (PF06602, IPR010569): Myotubularin-like phosphatase domain
3-PAP (PF12578, IPR022587): Myotubularin-associated protein
66 MYBoncoprotein100.4679.415Cmyb_C (PF09316, IPR015395): C-myb, C-terminal
LMSTEN (PF07988, IPR012642): LMSTEN motif
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
67 MYH7interactor100IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
68 NCLprotein found in more fusions140.42329.819DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
Myc_N (PF01056, IPR012682): Myc amino-terminal region
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
YL1 (PF05764, IPR008895): YL1 nuclear protein
Limkain-b1 (PF11608, IPR024582): Limkain b1
69 NPM1suppressor220.224202.976Nucleoplasmin (PF03066): Nucleoplasmin/nucleophosmin domain
SDA1 (PF05285, IPR007949): SDA1
NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
70 NSD1oncoprotein70.38112.824PHD (PF00628, IPR019787, SM00249): PHD-finger
PWWP (PF00855, IPR000313, SM00293): PWWP domain
SET (PF00856, IPR001214, SM00317): SET domain
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
71 NT5Einteractor1005_nucleotid_C (PF02872, IPR008334): 5'-nucleotidase, C-terminal domain
Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
72 OXTinteractor100Hormone_4 (PF00220, IPR022423): Neurohypophysial hormones, N-terminal Domain
Hormone_5 (PF00184, IPR000981, SM00003): Neurohypophysial hormones, C-terminal Domain
73 PAF1oncoprotein120.48525.626Paf1 (PF03985, IPR007133): Paf1
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
74 PCSK1interactor100P_proprotein (PF01483, IPR002884): Proprotein convertase P-domain
Peptidase_S8 (PF00082, IPR000209): Subtilase family
Proho_convert (PF12177, IPR022005): Prohormone convertase enzyme
Peptidase_S8_N (PF16361, IPR032304): N-terminal of Subtilase family
S8_pro-domain (PF16470, IPR032815): Peptidase S8 pro-domain
75 PIH1D1interactor21.0000PIH1 (PF08190, IPR012981): pre-RNA processing PIH1/Nop17
76 PKN1interactor60.8001.187C2 (PF00168, IPR000008, SM00239): C2 domain
HR1 (PF02185, IPR011072, SM00742): Hr1 repeat
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
77 POLR2Aprotein found in more fusions220.276196.991RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1
RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2
RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3
RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4
RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5
RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
78 PPIEinteractor31.0000Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
79 PPP1R15Ainteractor21.0000FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
PP1c_bdg (PF10488, IPR019523): Phosphatase-1 catalytic subunit binding region
SCHIP-1 (PF10148, IPR015649): Schwannomin-interacting protein 1
CAF1A (PF12253, IPR022043): Chromatin assembly factor 1 subunit A
80 PSIP1oncoprotein40.5002.455AT_hook (PF02178, IPR017956, SM00384): AT hook motif
BEX (PF04538, IPR021156): Brain expressed X-linked like family
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
PGA2 (PF07543, IPR011431): Protein trafficking PGA2
PWWP (PF00855, IPR000313, SM00293): PWWP domain
LEDGF (PF11467, IPR021567): Lens epithelium-derived growth factor (LEDGF)
TERB2 (PF15101, IPR028065): Telomere-associated protein TERB2
81 RANoncoprotein70.5717.396Ras (PF00071, IPR001806, SM00173): Ras family
82 RBBP4oncoprotein210.54835.416eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
83 RBBP5oncoprotein200.38059.696WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
84 RBBP7suppressor180.62716.692WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
85 RELAoncoprotein210.316112.518DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
86 RNF2interactor310.253270.743zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
87 RUNX1suppressor120.45542.420Runt (PF00853, IPR013524): Runt domain
RunxI (PF08504, IPR013711): Runx inhibition domain
DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037)
88 SAP30interactor81.0000Titin_Z (PF09042, IPR015129): Titin Z
zf-SAP30 (PF13866, IPR025717): SAP30 zinc-finger
SAP30_Sin3_bdg (PF13867, IPR025718): Sin3 binding region of histone deacetylase complex subunit SAP30
89 SBF1interactor21.0000dDENN (PF03455, IPR005112, SM00801): dDENN domain
DENN (PF02141, IPR001194, SM00799): DENN (AEX-3) domain
GRAM (PF02893, IPR004182, SM00568): GRAM domain
Myotub-related (PF06602, IPR010569): Myotubularin-like phosphatase domain
PH (PF00169, IPR001849, SM00233): PH domain
uDENN (PF03456, IPR005113, SM00800): uDENN domain
T2SSJ (PF11612, IPR010055): Type II secretion system (T2SS), protein J
SBF2 (PF12335, IPR022096): Myotubularin protein
90 SENP3interactor90.6117.704Nop53 (PF07767, IPR011687): Nop53 (60S ribosomal biogenesis)
Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain
91 SEToncoprotein50.5000.379NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP)
Nop14 (PF04147, IPR007276): Nop14-like family
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
92 SIAH1suppressor100.13982.515Sina (PF03145, IPR018121): Seven in absentia protein family
93 SIAH2oncoprotein31.0000Sina (PF03145, IPR018121): Seven in absentia protein family
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
94 SIN3Aoncoprotein260.40691.408Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor
PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat
Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein
95 SIRT7interactor230.285159.367DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
96 SKP2suppressor40.6673.710LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRR_2 (PF07723, IPR013101): Leucine Rich Repeat
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
F-box-like (PF12937, IPR001810): F-box-like
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
97 SLC16A6interactor100CBM_10 (PF02013, IPR002883, SM01064): Cellulose or protein binding domain
MFS_1 (PF07690, IPR011701): Major Facilitator Superfamily
98 SMAD9protein found in more fusions5020.401MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
99 SMARCA2suppressor240.44265.775DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168)
DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
HSA (PF07529, IPR014012, SM00573): HSA
QLQ (PF08880, IPR014978, SM00951): QLQ
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
YL1 (PF05764, IPR008895): YL1 nuclear protein
BRK (PF07533, IPR006576, SM00592): BRK domain
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
100 SMARCB1suppressor180.471100.556SNF5 (PF04855, IPR006939): SNF5 / SMARCB1 / INI1
101 SMARCC1suppressor160.50523.803SWIRM (PF04433, IPR007526): SWIRM domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF2618 (PF10940, IPR021237): Protein of unknown function (DUF2618)
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1
SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
102 SMARCC2interactor130.62812.099GHMP_kinases_N (PF00288, IPR006204): GHMP kinases N terminal domain
SWIRM (PF04433, IPR007526): SWIRM domain
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1
SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
103 SNW1protein found in more fusions220.295109.425SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
104 SVILinteractor30.6671.143Gelsolin (PF00626, IPR007123): Gelsolin repeat
VHP (PF02209, IPR003128, SM00153): Villin headpiece domain
DUF4695 (PF15766, IPR031521): Domain of unknown function (DUF4695)
105 SYMPKinteractor50.7001.787HEAT (PF02985, IPR000357): HEAT repeat
DUF3453 (PF11935, IPR021850): Domain of unknown function (DUF3453)
Symplekin_C (PF12295, IPR022075): Symplekin tight junction protein C terminal
Cohesin_HEAT (PF12765, IPR026003): HEAT repeat associated with sister chromatid cohesion
106 TAF1oncoprotein150.43845.306Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit
LcrG (PF07216, IPR009863): LcrG protein
Opi1 (PF08618, IPR013927): Transcription factor Opi1
Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region
PRP1_N (PF06424, IPR010491): PRP1 splicing factor, N-terminal
TBP-binding (PF09247, IPR009067): TATA box-binding protein binding
U3_snoRNA_assoc (PF08297, IPR013268): U3 snoRNA associated
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
DUF3591 (PF12157, IPR022591): Protein of unknown function (DUF3591)
zf-CCHC_6 (PF15288): Zinc knuckle
107 TAF6interactor210.52958.418CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain
Spo0A_C (PF08769, IPR014879): Sporulation initiation factor Spo0A C terminal
TAF (PF02969, IPR004823, SM00803): TATA box binding protein associated factor (TAF)
108 TAF9interactor100.73310.578TFIID-31kDa (PF02291, IPR003162): Transcription initiation factor IID, 31kD subunit
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
109 TASP1interactor100Asparaginase_2 (PF01112, IPR000246): Asparaginase
110 TBPprotein found in more fusions160.55230.612TBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP)
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
111 TOP1oncoprotein110.47343.445DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Topoisom_I (PF01028, IPR013500): Eukaryotic DNA topoisomerase I, catalytic core
Topoisom_I_N (PF02919, IPR008336): Eukaryotic DNA topoisomerase I, DNA binding fragment
MCM_bind (PF09739, IPR019140): Mini-chromosome maintenance replisome factor
Sox_N (PF12444, IPR022151): Sox developmental protein N terminal
Topo_C_assoc (PF14370, IPR025834): C-terminal topoisomerase domain
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
TonB_N (PF16031): TonB N-terminal region
112 TP53suppressor420.233483.821DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
113 WDR5interactor250.333138.789WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
114 WDR61interactor70.8102.000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
115 ZNF526interactor21.0000Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein
Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger

B a c k    t o    T o p ⇑


List of missing interactors (in fusions)

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 AFDNoncoproteinDIL (PF01843, IPR018444, SM01132): DIL domain
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
FHA (PF00498, IPR000253, SM00240): FHA domain
MAP7 (PF05672, IPR008604): MAP7 (E-MAP-115) family
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
Pap_E4 (PF02711, IPR003861): E4 protein
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
ARGLU (PF15346): Arginine and glutamate-rich 1
AM949750
2 AFF1parental proteinAF-4 (PF05110, IPR007797): AF-4 proto-oncoproteinAF024541, AF031404, AF177236, AF177237, AF177238, AF177239, AF397907, AF487905, AF487906, AF492831, AF492832, AJ430604, AM050744, AM050752, AM050754, AM050758, AM050762, AM050766, AM050772, AM050775, AM050795, AM050799, AM050802, AM949686, AM949687, AM949703, AM949711, AM949713, AM949733, AM949740, AM949749, AM949750, AM949753, DQ451148, FM177515, JN169752, KT444628, KT444629, KT444630, KT444631, KT444632, L22179
3 AFF4oncoproteinAF-4 (PF05110, IPR007797): AF-4 proto-oncoproteinAM050754, AM949713, AM949750
4 ASB2interactorAnk_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
SOCS_box (PF07525, IPR001496): SOCS box
AM050754, AM949713, AM949750
5 ASH2LinteractorSPRY (PF00622, IPR003877, SM00449): SPRY domain
PHD20L1_u1 (PF16660): PHD finger protein 20-like protein 1
AF024541, AF031404, AF177236, AF177237, AF487905, AF492832, AM050744, AM050752, AM050754, AM050758, AM050762, AM050772, AM050775, AM050799, AM949686, AM949687, AM949703, AM949713, AM949733, AM949740, AM949749, AM949750, DQ451148, FM177515, JN169752, KT444628, KT444629, KT444630
6 AVPinteractorProtamine_P1 (PF00260, IPR000221): Protamine P1AM050752, AM050754, AM050758, AM050772, AM949713, AM949750, FM177515
7 BMI1oncoproteinzf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
8 BRD4oncoproteinCaldesmon (PF02029, IPR006018): Caldesmon
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
Stm1_N (PF09598, IPR019084): Stm1
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
NAM-associated (PF14303, IPR029466): No apical meristem-associated C-terminal domain
BET (PF17035, IPR027353): Bromodomain extra-terminal - transcription regulation
BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4
AM050754, AM949713, AM949750
9 CARM1oncoproteinK_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
CBP_GIL (PF10995, IPR017745): GGDEF I-site like or GIL domain
CARM1 (PF11531, IPR020989): Coactivator-associated arginine methyltransferase 1 N terminal
AM050754, AM949713, AM949750
10 CBFBsuppressorCBF_beta (PF02312, IPR003417): Core binding factor beta subunitAF024541, AF031404, AF177236, AF177237, AF487905, AF492832, AM050744, AM050752, AM050754, AM050758, AM050762, AM050772, AM050775, AM050799, AM949687, AM949703, AM949713, AM949733, AM949740, AM949749, AM949750, DQ451148, FM177515, JN169752, KT444628, KT444629, KT444630
11 CBX4oncoproteinChromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
CBX7_C (PF17218): CBX family C-terminal motif
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
12 CBX8interactorAtrophin-1 (PF03154, IPR002951): Atrophin-1 family
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
RBR (PF17208): RNA binding Region
CBX7_C (PF17218): CBX family C-terminal motif
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
13 CCNT1oncoproteinCyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region
CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit
MDFI (PF15316, IPR026134): MyoD family inhibitor
AM949750
14 CDC73suppressorCDC73_C (PF05179, IPR007852): RNA pol II accessory factor, Cdc73 family, C-terminal
CDC73_N (PF16050, IPR032041): Paf1 complex subunit CDC73 N-terminal
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
15 CDK9interactorPkinase (PF00069, IPR000719): Protein kinase domainAM949750
16 CHD3oncoproteinCHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086)
DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087)
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF2956 (PF11169, IPR021339): Protein of unknown function (DUF2956)
FAM176 (PF14851): FAM176 family
AM050752, AM050758, AM949750, FM177515
17 CREBBPsuppressorCreb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
AM050752, AM050754, AM050758, AM949713, FM177515
18 CSNK2A2interactorPkinase (PF00069, IPR000719): Protein kinase domainAM050752, AM050754, AM050758, AM949713, AM949750, FM177515
19 CTBP1interactor2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
20 CTNNB1oncoproteinArm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
AM050752, AM050758, AM949750, FM177515
21 CTR9interactorDUF702 (PF05142, IPR007818): Domain of unknown function (DUF702)
Pap_E4 (PF02711, IPR003861): E4 protein
SPT16 (PF08644, IPR013953): FACT complex subunit (SPT16/CDC68)
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
DUF2175 (PF09943, IPR018686): Uncharacterized protein conserved in archaea (DUF2175)
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
AM949750
22 CXXC1interactorATP-synt_E (PF05680, IPR008386): ATP synthase E chain
PHD (PF00628, IPR019787, SM00249): PHD-finger
PLATZ (PF04640, IPR006734): PLATZ transcription factor
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
DUF2116 (PF09889, IPR019216): Uncharacterized protein containing a Zn-ribbon (DUF2116)
Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
DUF3347 (PF11827, IPR021782): Protein of unknown function (DUF3347)
zf-CpG_bind_C (PF12269, IPR022056): CpG binding protein zinc finger C terminal domain
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
23 DDX6oncoproteinDEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
AM949750
24 DOT1LoncoproteinAT_hook (PF02178, IPR017956, SM00384): AT hook motif
DivIC (PF04977, IPR007060): Septum formation initiator
DOT1 (PF08123, IPR013110): Histone methylation protein DOT1
ZapB (PF06005, IPR009252): Cell division protein ZapB
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
TraV (PF09676, IPR014118): Type IV conjugative transfer system lipoprotein (TraV)
AM949750
25 DYNLT1interactorTctex-1 (PF03645, IPR005334): Tctex-1 familyAM050752, AM050754, AM050758, AM949713, AM949750, FM177515
26 E2F2suppressorE2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain
E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
27 E2F4suppressorE2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain
Pheromone (PF08015, IPR012597): Fungal mating-type pheromone
SPX (PF03105, IPR004331): SPX domain
DUF3584 (PF12128, IPR021979): Protein of unknown function (DUF3584)
E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
28 E2F6oncoproteinBRCA-2_OB3 (PF09104, IPR015188): BRCA2, oligonucleotide/oligosaccharide-binding, domain 3
E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain
E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
29 EAF1suppressorMito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Peroxin-3 (PF04882, IPR006966): Peroxin-3
EAF (PF09816, IPR019194): RNA polymerase II transcription elongation factor
AF397907, AJ430604, AM050744, AM050754, AM050775, AM949687, AM949703, AM949713, AM949749, AM949750, AM949753, KT444632
30 ELLoncoproteinOccludin_ELL (PF07303, IPR010844): Occludin homology domain
ELL (PF10390, IPR019464): RNA polymerase II elongation factor ELL
AM050754, AM949713, AM949750
31 ELL2interactorOccludin_ELL (PF07303, IPR010844): Occludin homology domain
Wbp11 (PF09429, IPR019007): WW domain binding protein 11
ELL (PF10390, IPR019464): RNA polymerase II elongation factor ELL
AM050754, AM949686, AM949713, AM949750
32 ELL3interactorOccludin_ELL (PF07303, IPR010844): Occludin homology domain
ELL (PF10390, IPR019464): RNA polymerase II elongation factor ELL
TEX19 (PF15553, IPR029093): Testis-expressed protein 19
AM050744, AM050754, AM050775, AM949686, AM949687, AM949703, AM949713, AM949733, AM949749, AM949750
33 ELOBinteractorubiquitin (PF00240, IPR000626, SM00213): Ubiquitin familyAM050752, AM050754, AM050758, AM949713, AM949750, FM177515
34 ELOConcoproteinSkp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domainAM050752, AM050754, AM050758, AM949713, AM949750, FM177515
35 EWSR1oncoproteinRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
36 H2BC8oncoproteinHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
37 H3-3AoncoproteinHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
38 H3-4interactorHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
39 H3C1interactorHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
40 H3C14interactorHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
41 H4C1interactorCENP-T_C (PF15511): Centromere kinetochore component CENP-T histone foldAM050752, AM050754, AM050758, AM949686, AM949713, AM949750, FM177515
42 HCFC1interactorfn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
zf-tcix (PF14952, IPR029269): Putative treble-clef, zinc-finger, Zn-binding
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
43 HCFC2interactorfn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
44 HDAC2suppressorHist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
45 HECW2interactorC2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
RFXA_RFXANK_bdg (PF15289, IPR029316): Regulatory factor X-associated C-terminal binding domain
HECW_N (PF16562, IPR032348): N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
46 HEXIM1oncoproteinAPG6 (PF04111, IPR007243): Autophagy protein Apg6
DivIC (PF04977, IPR007060): Septum formation initiator
Shugoshin_N (PF07558, IPR011516): Shugoshin N-terminal coiled-coil region
HEXIM (PF15313, IPR024872): Hexamethylene bis-acetamide-inducible protein
AF397907, AJ430604, AM050754, AM949686, AM949713, AM949750, AM949753, KT444632
47 ING4suppressorPHD (PF00628, IPR019787, SM00249): PHD-finger
SOGA (PF11365, IPR027881): Protein SOGA
ING (PF12998, IPR024610): Inhibitor of growth proteins N-terminal histone-binding
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
48 INSinteractorInsulin (PF00049, IPR016179, SM00078): Insulin/IGF/Relaxin familyAF024541, AF031404, AF177236, AF177237, AF487905, AF492832, AM050744, AM050752, AM050754, AM050758, AM050762, AM050772, AM050775, AM050799, AM949687, AM949703, AM949713, AM949733, AM949740, AM949749, AM949750, DQ451148, FM177515, JN169752, KT444628, KT444629, KT444630
49 KAT6AoncoproteinBUD22 (PF09073, IPR015158): BUD22
MOZ_SAS (PF01853, IPR002717): MOZ/SAS family
PHD (PF00628, IPR019787, SM00249): PHD-finger
Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
zf-met (PF12874): Zinc-finger of C2H2 type
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
50 KAT8interactorMOZ_SAS (PF01853, IPR002717): MOZ/SAS family
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
51 KIF11interactorBaculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2
DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
Gag_p17 (PF00540, IPR000071): gag gene protein p17 (matrix protein)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
DUF3510 (PF12022, IPR024603): Domain of unknown function (DUF3510)
Microtub_bind (PF13931, IPR025901): Kinesin-associated microtubule-binding
AM050752, AM050758, AM949750, FM177515
52 KMT2Aparental proteinAT_hook (PF02178, IPR017956, SM00384): AT hook motif
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus
FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus
Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
SET (PF00856, IPR001214, SM00317): SET domain
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
AF024541, AF031404, AF177236, AF177237, AF177238, AF177239, AF397907, AF487905, AF487906, AF492831, AF492832, AJ430604, AM050744, AM050752, AM050754, AM050758, AM050762, AM050766, AM050772, AM050775, AM050795, AM050799, AM050802, AM949686, AM949687, AM949703, AM949711, AM949713, AM949733, AM949740, AM949749, AM949750, AM949753, DQ451148, FM177515, JN169752, KT444628, KT444629, KT444630, KT444631, KT444632, L22179
53 KRASoncoproteinRas (PF00071, IPR001806, SM00173): Ras familyAM050752, AM050754, AM050758, AM949713, AM949750, FM177515
54 LARP7interactorAgouti (PF05039, IPR007733, SM00792): Agouti protein
DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
La (PF05383, IPR006630, SM00715): La domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RRM_3 (PF08777, IPR014886): RNA binding motif
AM949750
55 LEO1interactorLeo1 (PF04004, IPR007149): Leo1-like protein
PPP4R2 (PF09184, IPR015267): PPP4R2
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
56 LGR4interactor7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
AM050752, AM050758, AM949750, FM177515
57 MAP3K5oncoproteinPkinase (PF00069, IPR000719): Protein kinase domain
DUF4071 (PF13281, IPR025136): Domain of unknown function (DUF4071)
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
58 MBD3interactorDUF2201_N (PF13203, IPR025154): Putative metallopeptidase domainAM050752, AM050754, AM050758, AM949713, AM949750, FM177515
59 MED26interactorMed26 (PF08711, IPR017923): TFIIS helical bundle-like domain
Med26_C (PF15693, IPR031416): Mediator complex subunit 26 C-terminal
Med26_M (PF15694, IPR031417): Mediator complex subunit 26 middle domain
AF397907, AJ430604, AM050754, AM050766, AM050795, AM949686, AM949711, AM949713, AM949750, AM949753, KT444632
60 MEN1suppressorMenin (PF05053, IPR007747): MeninAM050744, AM050752, AM050754, AM050758, AM050775, AM949686, AM949687, AM949713, AM949750, FM177515
61 MLLT1oncoproteinDUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
Peptidase_S64 (PF08192, IPR012985): Peptidase family S64
YEATS (PF03366, IPR005033): YEATS family
DDRGK (PF09756, IPR019153, SM01128): DDRGK domain
AM050754, AM949713, AM949750
62 MLLT10oncoproteinSpoIIIAH (PF12685, IPR024232): SpoIIIAH-like protein
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
PHD_2 (PF13831): PHD-finger
zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain
Tnp_zf-ribbon_2 (PF13842, IPR032718): DDE_Tnp_1-like zinc-ribbon
CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106
DUF4718 (PF15842, IPR031695): Domain of unknown function (DUF4718)
DUF4887 (PF16228, IPR032615): Domain of unknown function (DUF4887)
AP3D1 (PF06375): AP-3 complex subunit delta-1
AM050754, AM949713, AM949750
63 MLLT3oncoproteinPeptidase_S64 (PF08192, IPR012985): Peptidase family S64
YEATS (PF03366, IPR005033): YEATS family
DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446)
Sox_N (PF12444, IPR022151): Sox developmental protein N terminal
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
NKAP (PF15692): NF-kappa-B-activating protein
BET (PF17035, IPR027353): Bromodomain extra-terminal - transcription regulation
AM050754, AM949713, AM949750
64 MTM1interactorGRAM (PF02893, IPR004182, SM00568): GRAM domain
Myotub-related (PF06602, IPR010569): Myotubularin-like phosphatase domain
3-PAP (PF12578, IPR022587): Myotubularin-associated protein
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
65 MYBoncoproteinCmyb_C (PF09316, IPR015395): C-myb, C-terminal
LMSTEN (PF07988, IPR012642): LMSTEN motif
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
66 NCLinteractorDUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
Myc_N (PF01056, IPR012682): Myc amino-terminal region
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
YL1 (PF05764, IPR008895): YL1 nuclear protein
Limkain-b1 (PF11608, IPR024582): Limkain b1
AM050752, AM050758, AM949750, FM177515
67 NPM1suppressorNucleoplasmin (PF03066): Nucleoplasmin/nucleophosmin domain
SDA1 (PF05285, IPR007949): SDA1
NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
AM949750
68 NSD1oncoproteinPHD (PF00628, IPR019787, SM00249): PHD-finger
PWWP (PF00855, IPR000313, SM00293): PWWP domain
SET (PF00856, IPR001214, SM00317): SET domain
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
AM949750
69 NT5Einteractor5_nucleotid_C (PF02872, IPR008334): 5'-nucleotidase, C-terminal domain
Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
AF397907, AJ430604, AM050744, AM050754, AM050766, AM050775, AM050795, AM050802, AM949686, AM949687, AM949713, AM949733, AM949749, AM949750, AM949753, KT444632
70 OXTinteractorHormone_4 (PF00220, IPR022423): Neurohypophysial hormones, N-terminal Domain
Hormone_5 (PF00184, IPR000981, SM00003): Neurohypophysial hormones, C-terminal Domain
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
71 PAF1oncoproteinPaf1 (PF03985, IPR007133): Paf1
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
72 PCSK1interactorP_proprotein (PF01483, IPR002884): Proprotein convertase P-domain
Peptidase_S8 (PF00082, IPR000209): Subtilase family
Proho_convert (PF12177, IPR022005): Prohormone convertase enzyme
Peptidase_S8_N (PF16361, IPR032304): N-terminal of Subtilase family
S8_pro-domain (PF16470, IPR032815): Peptidase S8 pro-domain
AF397907, AJ430604, AM050744, AM050754, AM050766, AM050775, AM050795, AM050802, AM949686, AM949687, AM949703, AM949711, AM949713, AM949733, AM949749, AM949750, AM949753, KT444632
73 PIH1D1interactorPIH1 (PF08190, IPR012981): pre-RNA processing PIH1/Nop17AF487905, AM050744, AM050752, AM050754, AM050758, AM050762, AM050775, AM949687, AM949703, AM949713, AM949749, AM949750, FM177515
74 PKN1interactorC2 (PF00168, IPR000008, SM00239): C2 domain
HR1 (PF02185, IPR011072, SM00742): Hr1 repeat
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
AM050752, AM050758, AM949750, FM177515
75 POLR2AinteractorRNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1
RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2
RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3
RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4
RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5
RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
AM050754, AM949713
76 PPIEinteractorPro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
77 PPP1R15AinteractorFSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
PP1c_bdg (PF10488, IPR019523): Phosphatase-1 catalytic subunit binding region
SCHIP-1 (PF10148, IPR015649): Schwannomin-interacting protein 1
CAF1A (PF12253, IPR022043): Chromatin assembly factor 1 subunit A
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
78 PSIP1oncoproteinAT_hook (PF02178, IPR017956, SM00384): AT hook motif
BEX (PF04538, IPR021156): Brain expressed X-linked like family
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
PGA2 (PF07543, IPR011431): Protein trafficking PGA2
PWWP (PF00855, IPR000313, SM00293): PWWP domain
LEDGF (PF11467, IPR021567): Lens epithelium-derived growth factor (LEDGF)
TERB2 (PF15101, IPR028065): Telomere-associated protein TERB2
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
79 RANoncoproteinRas (PF00071, IPR001806, SM00173): Ras familyAM050752, AM050754, AM050758, AM949713, AM949750, FM177515
80 RBBP4oncoproteineIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
AM050752, AM050758, AM949750, FM177515
81 RBBP5oncoproteinWD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
82 RBBP7suppressorWD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
AM050752, AM050758, AM949750, FM177515
83 RNF2interactorzf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
84 RUNX1suppressorRunt (PF00853, IPR013524): Runt domain
RunxI (PF08504, IPR013711): Runx inhibition domain
DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037)
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
85 SAP30interactorTitin_Z (PF09042, IPR015129): Titin Z
zf-SAP30 (PF13866, IPR025717): SAP30 zinc-finger
SAP30_Sin3_bdg (PF13867, IPR025718): Sin3 binding region of histone deacetylase complex subunit SAP30
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
86 SBF1interactordDENN (PF03455, IPR005112, SM00801): dDENN domain
DENN (PF02141, IPR001194, SM00799): DENN (AEX-3) domain
GRAM (PF02893, IPR004182, SM00568): GRAM domain
Myotub-related (PF06602, IPR010569): Myotubularin-like phosphatase domain
PH (PF00169, IPR001849, SM00233): PH domain
uDENN (PF03456, IPR005113, SM00800): uDENN domain
T2SSJ (PF11612, IPR010055): Type II secretion system (T2SS), protein J
SBF2 (PF12335, IPR022096): Myotubularin protein
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
87 SENP3interactorNop53 (PF07767, IPR011687): Nop53 (60S ribosomal biogenesis)
Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain
AF024541, AF031404, AF177236, AF177237, AF487905, AF492832, AM050744, AM050752, AM050754, AM050758, AM050762, AM050772, AM050775, AM050799, AM949686, AM949687, AM949703, AM949713, AM949733, AM949740, AM949749, AM949750, DQ451148, FM177515, KT444628, KT444629, KT444630
88 SEToncoproteinNAP (PF00956, IPR002164): Nucleosome assembly protein (NAP)
Nop14 (PF04147, IPR007276): Nop14-like family
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
89 SIAH1suppressorSina (PF03145, IPR018121): Seven in absentia protein familyAF397907, AJ430604, AM050744, AM050754, AM050766, AM050775, AM050795, AM050802, AM949686, AM949687, AM949703, AM949711, AM949713, AM949733, AM949749, AM949750, AM949753, KT444632
90 SIAH2oncoproteinSina (PF03145, IPR018121): Seven in absentia protein family
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
AM050754, AM949713, AM949750
91 SIN3AoncoproteinSin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor
PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat
Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
92 SIRT7interactorDUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
93 SKP2suppressorLRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRR_2 (PF07723, IPR013101): Leucine Rich Repeat
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
F-box-like (PF12937, IPR001810): F-box-like
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
94 SLC16A6interactorCBM_10 (PF02013, IPR002883, SM01064): Cellulose or protein binding domain
MFS_1 (PF07690, IPR011701): Major Facilitator Superfamily
AF397907, AJ430604, AM050744, AM050754, AM050766, AM050775, AM050795, AM050802, AM949686, AM949687, AM949703, AM949711, AM949713, AM949733, AM949749, AM949750, AM949753, KT444632
95 SMARCA2suppressorDUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168)
DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
HSA (PF07529, IPR014012, SM00573): HSA
QLQ (PF08880, IPR014978, SM00951): QLQ
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
YL1 (PF05764, IPR008895): YL1 nuclear protein
BRK (PF07533, IPR006576, SM00592): BRK domain
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
96 SMARCB1suppressorSNF5 (PF04855, IPR006939): SNF5 / SMARCB1 / INI1AF024541, AF031404, AF177236, AF177237, AF487905, AF492832, AM050744, AM050752, AM050754, AM050758, AM050762, AM050772, AM050775, AM050799, AM949686, AM949687, AM949703, AM949713, AM949733, AM949740, AM949749, AM949750, DQ451148, FM177515, JN169752, KT444628, KT444629, KT444630
97 SMARCC1suppressorSWIRM (PF04433, IPR007526): SWIRM domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF2618 (PF10940, IPR021237): Protein of unknown function (DUF2618)
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1
SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
98 SMARCC2interactorGHMP_kinases_N (PF00288, IPR006204): GHMP kinases N terminal domain
SWIRM (PF04433, IPR007526): SWIRM domain
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1
SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
99 SNW1interactorSKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
100 SVILinteractorGelsolin (PF00626, IPR007123): Gelsolin repeat
VHP (PF02209, IPR003128, SM00153): Villin headpiece domain
DUF4695 (PF15766, IPR031521): Domain of unknown function (DUF4695)
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
101 SYMPKinteractorHEAT (PF02985, IPR000357): HEAT repeat
DUF3453 (PF11935, IPR021850): Domain of unknown function (DUF3453)
Symplekin_C (PF12295, IPR022075): Symplekin tight junction protein C terminal
Cohesin_HEAT (PF12765, IPR026003): HEAT repeat associated with sister chromatid cohesion
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
102 TAF1oncoproteinExonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit
LcrG (PF07216, IPR009863): LcrG protein
Opi1 (PF08618, IPR013927): Transcription factor Opi1
Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region
PRP1_N (PF06424, IPR010491): PRP1 splicing factor, N-terminal
TBP-binding (PF09247, IPR009067): TATA box-binding protein binding
U3_snoRNA_assoc (PF08297, IPR013268): U3 snoRNA associated
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
DUF3591 (PF12157, IPR022591): Protein of unknown function (DUF3591)
zf-CCHC_6 (PF15288): Zinc knuckle
AM050752, AM050758, AM949750, FM177515
103 TAF6interactorCAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain
Spo0A_C (PF08769, IPR014879): Sporulation initiation factor Spo0A C terminal
TAF (PF02969, IPR004823, SM00803): TATA box binding protein associated factor (TAF)
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
104 TAF9interactorTFIID-31kDa (PF02291, IPR003162): Transcription initiation factor IID, 31kD subunit
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
105 TASP1interactorAsparaginase_2 (PF01112, IPR000246): AsparaginaseAF024541, AF031404, AF177236, AF177237, AF487905, AF492832, AM050744, AM050752, AM050754, AM050758, AM050762, AM050772, AM050775, AM050799, AM949687, AM949703, AM949713, AM949733, AM949740, AM949749, AM949750, DQ451148, FM177515, JN169752, KT444628, KT444629, KT444630
106 TBPinteractorTBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP)
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
AM050754, AM949713, AM949750
107 TOP1oncoproteinDUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Topoisom_I (PF01028, IPR013500): Eukaryotic DNA topoisomerase I, catalytic core
Topoisom_I_N (PF02919, IPR008336): Eukaryotic DNA topoisomerase I, DNA binding fragment
MCM_bind (PF09739, IPR019140): Mini-chromosome maintenance replisome factor
Sox_N (PF12444, IPR022151): Sox developmental protein N terminal
Topo_C_assoc (PF14370, IPR025834): C-terminal topoisomerase domain
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
TonB_N (PF16031): TonB N-terminal region
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
108 TP53suppressorDEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
AM050752, AM050754, AM050758, AM949713, AM949750, FM177515
109 WDR5interactorWD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeatAM050752, AM050754, AM050758, AM949713, AM949750, FM177515
110 WDR61interactorWD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
AM050752, AM050758, AM949750, FM177515

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