1 |
AFF1 | parental protein | 32 | 0.176 | 593.002 | AF-4 (PF05110, IPR007797): AF-4 proto-oncoprotein |
2 |
AFF4 | oncoprotein | 12 | 0.636 | 13.302 | AF-4 (PF05110, IPR007797): AF-4 proto-oncoprotein |
3 |
BRD4 | oncoprotein | 5 | 0.900 | 0.400 | Caldesmon (PF02029, IPR006018): Caldesmon Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region Stm1_N (PF09598, IPR019084): Stm1 SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain NAM-associated (PF14303, IPR029466): No apical meristem-associated C-terminal domain BET (PF17035, IPR027353): Bromodomain extra-terminal - transcription regulation BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4 |
4 |
CARM1 | oncoprotein | 2 | 1.000 | 0 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase CBP_GIL (PF10995, IPR017745): GGDEF I-site like or GIL domain CARM1 (PF11531, IPR020989): Coactivator-associated arginine methyltransferase 1 N terminal |
5 |
CCNT1 | oncoprotein | 14 | 0.577 | 16.619 | Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit MDFI (PF15316, IPR026134): MyoD family inhibitor |
6 |
CDK9 | protein found in more fusions | 15 | 0.549 | 22.869 | Pkinase (PF00069, IPR000719): Protein kinase domain |
7 |
DDX6 | oncoprotein | 1 | 0 | 0 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
8 |
DOT1L | oncoprotein | 7 | 0.667 | 4.833 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif DivIC (PF04977, IPR007060): Septum formation initiator DOT1 (PF08123, IPR013110): Histone methylation protein DOT1 ZapB (PF06005, IPR009252): Cell division protein ZapB HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper TraV (PF09676, IPR014118): Type IV conjugative transfer system lipoprotein (TraV) |
9 |
EAF1 | suppressor | 8 | 0.893 | 1.000 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Peroxin-3 (PF04882, IPR006966): Peroxin-3 EAF (PF09816, IPR019194): RNA polymerase II transcription elongation factor |
10 |
ELL2 | interactor | 9 | 0.806 | 4.250 | Occludin_ELL (PF07303, IPR010844): Occludin homology domain Wbp11 (PF09429, IPR019007): WW domain binding protein 11 ELL (PF10390, IPR019464): RNA polymerase II elongation factor ELL |
11 |
ELL3 | interactor | 6 | 0.933 | 0.250 | Occludin_ELL (PF07303, IPR010844): Occludin homology domain ELL (PF10390, IPR019464): RNA polymerase II elongation factor ELL TEX19 (PF15553, IPR029093): Testis-expressed protein 19 |
12 |
HDAC1 | suppressor | 8 | 0.524 | 6.567 | FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
13 |
HEXIM1 | oncoprotein | 8 | 0.607 | 6.300 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 DivIC (PF04977, IPR007060): Septum formation initiator Shugoshin_N (PF07558, IPR011516): Shugoshin N-terminal coiled-coil region HEXIM (PF15313, IPR024872): Hexamethylene bis-acetamide-inducible protein |
14 |
HIST3H3 | interactor | 7 | 0.571 | 6.000 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
15 |
KMT2A | oncoprotein | 11 | 0.600 | 10.233 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 SET (PF00856, IPR001214, SM00317): SET domain zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain zf-HC5HC2H (PF13771): PHD-like zinc-binding domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) |
16 |
LARP7 | interactor | 5 | 0.800 | 0.900 | Agouti (PF05039, IPR007733, SM00792): Agouti protein DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) La (PF05383, IPR006630, SM00715): La domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 (PF08777, IPR014886): RNA binding motif |
17 |
MED26 | interactor | 9 | 0.861 | 1.817 | Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain Med26_C (PF15693, IPR031416): Mediator complex subunit 26 C-terminal Med26_M (PF15694, IPR031417): Mediator complex subunit 26 middle domain |
18 |
MLLT1 | oncoprotein | 15 | 0.514 | 30.802 | DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) Peptidase_S64 (PF08192, IPR012985): Peptidase family S64 YEATS (PF03366, IPR005033): YEATS family DDRGK (PF09756, IPR019153, SM01128): DDRGK domain |
19 |
MLLT10 | oncoprotein | 6 | 0.700 | 3.000 | SpoIIIAH (PF12685, IPR024232): SpoIIIAH-like protein CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal PHD_2 (PF13831): PHD-finger zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain Tnp_zf-ribbon_2 (PF13842, IPR032718): DDE_Tnp_1-like zinc-ribbon CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106 DUF4718 (PF15842, IPR031695): Domain of unknown function (DUF4718) DUF4887 (PF16228, IPR032615): Domain of unknown function (DUF4887) AP3D1 (PF06375): AP-3 complex subunit delta-1 |
20 |
MLLT3 | oncoprotein | 12 | 0.652 | 12.002 | Peptidase_S64 (PF08192, IPR012985): Peptidase family S64 YEATS (PF03366, IPR005033): YEATS family DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446) Sox_N (PF12444, IPR022151): Sox developmental protein N terminal PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal NKAP (PF15692): NF-kappa-B-activating protein BET (PF17035, IPR027353): Bromodomain extra-terminal - transcription regulation |
21 |
MYH7 | interactor | 1 | 0 | 0 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
22 |
NPM1 | suppressor | 7 | 0.533 | 6.000 | Nucleoplasmin (PF03066): Nucleoplasmin SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain |
23 |
NSD1 | oncoprotein | 4 | 0.667 | 1.000 | PHD (PF00628, IPR019787, SM00249): PHD-finger PWWP (PF00855, IPR000313, SM00293): PWWP domain SET (PF00856, IPR001214, SM00317): SET domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain |
24 |
NT5E | interactor | 1 | 0 | 0 | 5_nucleotid_C (PF02872, IPR008334): 5'-nucleotidase, C-terminal domain Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase |
25 |
PCSK1 | interactor | 1 | 0 | 0 | P_proprotein (PF01483, IPR002884): Proprotein convertase P-domain Peptidase_S8 (PF00082, IPR000209): Subtilase family Proho_convert (PF12177, IPR022005): Prohormone convertase enzyme Peptidase_S8_N (PF16361, IPR032304): N-terminal of Subtilase family S8_pro-domain (PF16470, IPR032815): Peptidase S8 pro-domain |
26 |
POLR2A | protein found in more fusions | 9 | 0.643 | 6.619 | RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat |
27 |
RELA | oncoprotein | 9 | 0.429 | 13.233 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
28 |
SIAH1 | suppressor | 6 | 0.500 | 5.000 | Sina (PF03145, IPR018121): Seven in absentia protein family |
29 |
SIAH2 | oncoprotein | 3 | 1.000 | 0 | Sina (PF03145, IPR018121): Seven in absentia protein family zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
30 |
SLC16A6 | interactor | 1 | 0 | 0 | CBM_10 (PF02013, IPR002883, SM01064): Cellulose or protein binding domain MFS_1 (PF07690, IPR011701): Major Facilitator Superfamily |
31 |
SMAD9 | interactor | 2 | 0 | 0 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
32 |
ZNF526 | interactor | 2 | 1.000 | 0 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger |