1 |
ACTG1 | parental protein | 125 | 0.096 | 8979.590 | Actin (PF00022, IPR004000, SM00268): Actin |
2 |
ACTA1 | interactor | 31 | 0.222 | 234.175 | Actin (PF00022, IPR004000, SM00268): Actin |
3 |
ACTB | oncoprotein | 53 | 0.198 | 692.501 | Actin (PF00022, IPR004000, SM00268): Actin |
4 |
ACTBL2 | interactor | 13 | 0.321 | 26.275 | Actin (PF00022, IPR004000, SM00268): Actin |
5 |
ADRB2 | interactor | 7 | 0.467 | 2.127 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) |
6 |
AICDA | interactor | 4 | 0.667 | 0.118 | APOBEC_N (PF08210, IPR013158): APOBEC-like N-terminal domain |
7 |
ANLN | oncoprotein | 14 | 0.923 | 1.140 | Anillin (PF08174, IPR012966): Cell division protein anillin PH (PF00169, IPR001849, SM00233): PH domain Anillin_N (PF16018, IPR031970): Anillin N-terminus |
8 |
APOE | protein found in more fusions | 2 | 0 | 0 | Apolipoprotein (PF01442, IPR000074): Apolipoprotein A1/A4/E domain TipAS (PF07739, IPR012925): TipAS antibiotic-recognition domain |
9 |
BCAP31 | protein found in more fusions | 5 | 0.667 | 0.722 | Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) |
10 |
BMI1 | oncoprotein | 12 | 0.382 | 18.399 | zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
11 |
BRCA1 | suppressor | 18 | 0.375 | 46.644 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT |
12 |
BRK1 | interactor | 5 | 0.900 | 0.500 | DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) |
13 |
CAD | oncoprotein | 17 | 0.471 | 23.738 | Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 (PF02787, IPR005480, SM01096): Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_sm_chain (PF00988, IPR002474, SM01097): Carbamoyl-phosphate synthase small chain, CPSase domain GATase (PF00117, IPR017926): Glutamine amidotransferase class-I MGS (PF02142, IPR011607, SM00851): MGS-like domain OTCace (PF00185, IPR006131): Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N (PF02729, IPR006132): Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain ATPgrasp_Ter (PF15632, IPR011226): ATP-grasp in the biosynthetic pathway with Ter operon |
14 |
CAP1 | interactor | 12 | 0.400 | 19.948 | CAP_C (PF08603, IPR013912): Adenylate cyclase associated (CAP) C terminal CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator |
15 |
CAP2 | interactor | 7 | 0.600 | 4.167 | CAP_C (PF08603, IPR013912): Adenylate cyclase associated (CAP) C terminal CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator |
16 |
CAPZA2 | interactor | 24 | 0.551 | 52.230 | F-actin_cap_A (PF01267, IPR002189): F-actin capping protein alpha subunit |
17 |
CCDC22 | interactor | 2 | 1.000 | 0 | DUF812 (PF05667, IPR008530): Protein of unknown function (DUF812) HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate |
18 |
CCDC8 | interactor | 18 | 0.419 | 28.939 | Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA |
19 |
CDH1 | suppressor | 9 | 0.464 | 7.926 | Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like Cadherin (PF00028, IPR002126, SM00112): Cadherin domain |
20 |
CDK2 | suppressor | 31 | 0.391 | 99.015 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
21 |
CDKN2A | suppressor | 21 | 0.333 | 74.371 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
22 |
CFL1 | protein found in more fusions | 29 | 0.404 | 120.714 | Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein |
23 |
CFL2 | interactor | 16 | 0.790 | 8.621 | Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein |
24 |
CORO1B | interactor | 16 | 0.750 | 9.606 | DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899) Trimer_CC (PF08954, IPR015049, SM01167): Trimerisation motif WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_4 (PF16300): Type of WD40 repeat |
25 |
CORO1C | oncoprotein | 20 | 0.642 | 20.152 | DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat WD40_4 (PF16300): Type of WD40 repeat |
26 |
COTL1 | oncoprotein | 5 | 0.800 | 0.206 | Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein |
27 |
CTBP2 | protein found in more fusions | 3 | 1.000 | 0 | 2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain |
28 |
CTNND1 | suppressor | 7 | 0.333 | 6.586 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Ebp2 (PF05890, IPR008610): Eukaryotic rRNA processing protein EBP2 Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain |
29 |
CTTN | oncoprotein | 18 | 0.515 | 40.714 | FadA (PF09403, IPR018543): Adhesion protein FadA HS1_rep (PF02218, IPR003134): Repeat in HS1/Cortactin SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
30 |
DBN1 | oncoprotein | 31 | 0.391 | 133.907 | Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c |
31 |
DISC1 | interactor | 5 | 0.400 | 5.400 | HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper Mnd1 (PF03962, IPR005647): Mnd1 family TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Tropomyosin (PF00261, IPR000533): Tropomyosin UVR (PF02151, IPR001943): UvrB/uvrC motif CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding |
32 |
DMAP1 | interactor | 11 | 0.745 | 4.791 | DMAP1 (PF05499, IPR008468): DNA methyltransferase 1-associated protein 1 (DMAP1) SANT_DAMP1_like (PF16282, IPR032563): SANT/Myb-like domain of DAMP1 |
33 |
DSTN | interactor | 11 | 0.709 | 3.672 | Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein |
34 |
EED | suppressor | 20 | 0.333 | 54.290 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
35 |
EEF1A1 | suppressor | 32 | 0.232 | 211.153 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
36 |
EEF1A2 | oncoprotein | 6 | 0.467 | 3.452 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
37 |
EHHADH | interactor | 2 | 1.000 | 0 | 2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH (PF00725, IPR006108): 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 3HCDH_N (PF02737, IPR006176): 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase |
38 |
EIF6 | interactor | 6 | 0.467 | 3.375 | eIF-6 (PF01912, IPR002769, SM00654): eIF-6 family |
39 |
EPS8L1 | interactor | 2 | 1.000 | 0 | PTB (PF08416, IPR013625): Phosphotyrosine-binding domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 TetR_C_11 (PF16859, IPR011075): Bacterial transcriptional repressor C-terminal |
40 |
EPS8L2 | interactor | 1 | 0 | 0 | PTB (PF08416, IPR013625): Phosphotyrosine-binding domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
41 |
ERBB3 | oncoprotein | 12 | 0.491 | 14.280 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
42 |
ERRFI1 | suppressor | 10 | 0.556 | 6.139 | GTPase_binding (PF09027, IPR015116): GTPase binding Inhibitor_Mig-6 (PF11555, IPR021619): EGFR receptor inhibitor Mig-6 |
43 |
EZH2 | suppressor | 12 | 0.418 | 18.467 | CDC45 (PF02724, IPR003874): CDC45-like protein TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain SET (PF00856, IPR001214, SM00317): SET domain EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal |
44 |
FAF2 | interactor | 8 | 0.429 | 7.510 | DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682) UBX (PF00789, IPR001012, SM00166): UBX domain Thioredoxin_7 (PF13899): Thioredoxin-like UBA_4 (PF14555): UBA-like domain |
45 |
FBXO25 | suppressor | 16 | 0.433 | 29.917 | Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A |
46 |
FBXO6 | interactor | 14 | 0.396 | 20.477 | FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like |
47 |
FEZ1 | interactor | 3 | 1.000 | 0 | FEZ (PF07763, IPR011680): FEZ-like protein DUF5102 (PF17104, IPR031355): Domain of unknown function (DUF5102) |
48 |
FHOD1 | interactor | 6 | 0.600 | 2.567 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator FH2 (PF02181, IPR015425, SM00498): Formin Homology 2 Domain |
49 |
FLNA | suppressor | 35 | 0.398 | 167.252 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Filamin (PF00630, IPR017868): Filamin/ABP280 repeat |
50 |
FN1 | oncoprotein | 28 | 0.370 | 104.593 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
51 |
GAN | protein found in more fusions | 9 | 0.286 | 11.372 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif |
52 |
GIT2 | interactor | 2 | 0 | 0 | ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf Sen15 (PF09631, IPR018593): Sen15 protein GIT_SHD (PF08518, IPR013724, SM00555): Spa2 homology domain (SHD) of GIT GIT1_C (PF12205, IPR022018): G protein-coupled receptor kinase-interacting protein 1 C term Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) DUF4482 (PF14818, IPR027882): Domain of unknown function (DUF4482) GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor |
53 |
GRB2 | oncoprotein | 29 | 0.354 | 132.648 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093) |
54 |
GZMA | interactor | 3 | 1.000 | 0 | Trypsin (PF00089, IPR001254, SM00020): Trypsin |
55 |
GZMK | interactor | 2 | 1.000 | 0 | Trypsin (PF00089, IPR001254, SM00020): Trypsin |
56 |
HIST1H3E | interactor | 11 | 0.436 | 10.252 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
57 |
HSP90AA1 | oncoprotein | 33 | 0.254 | 200.517 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
58 |
HSP90AB1 | oncoprotein | 31 | 0.294 | 141.420 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
59 |
HSPA5 | oncoprotein | 35 | 0.280 | 214.657 | HSP70 (PF00012, IPR013126): Hsp70 protein |
60 |
HSPB2 | interactor | 7 | 0.467 | 3.349 | Crystallin (PF00525, IPR003090): Alpha crystallin A chain, N terminal HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family |
61 |
ILF3 | oncoprotein | 23 | 0.308 | 74.861 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif DZF (PF07528, IPR006561, SM00572): DZF domain |
62 |
IQGAP1 | interactor | 39 | 0.377 | 180.219 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF87 (PF01935, IPR002789): Domain of unknown function DUF87 IDEAL (PF08858, IPR014957, SM00914): IDEAL domain IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase RasGAP_C (PF03836, IPR000593): RasGAP C-terminus WW (PF00397, IPR001202, SM00456): WW domain |
63 |
ITGA4 | interactor | 20 | 0.462 | 32.792 | FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha |
64 |
KAT5 | suppressor | 16 | 0.552 | 18.897 | MOZ_SAS (PF01853, IPR002717): MOZ/SAS family Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain |
65 |
LGR4 | interactor | 9 | 0.536 | 3.794 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat |
66 |
LIG4 | interactor | 6 | 0.400 | 5.536 | APG17 (PF04108, IPR007240): Autophagy protein Apg17 BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain DNA_ligase_A_C (PF04679, IPR012309): ATP dependent DNA ligase C terminal region DNA_ligase_A_M (PF01068, IPR012310): ATP dependent DNA ligase domain DNA_ligase_A_N (PF04675, IPR012308): DNA ligase N terminus DNA_ligase_IV (PF11411, IPR021536): DNA ligase IV RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
67 |
LIMA1 | suppressor | 29 | 0.458 | 89.624 | LIM (PF00412, IPR001781, SM00132): LIM domain ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain |
68 |
LRRK2 | oncoprotein | 15 | 0.385 | 26.720 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain DUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043) T2SSE (PF00437, IPR001482): Type II/IV secretion system protein Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase Pkinase (PF00069, IPR000719): Protein kinase domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) PQQ_2 (PF13360, IPR002372): PQQ-like domain LRR_8 (PF13855, IPR001611): Leucine rich repeat COR (PF16095, IPR032171): C-terminal of Roc, COR, domain |
69 |
MAPK6 | oncoprotein | 8 | 0.429 | 8.079 | Pkinase (PF00069, IPR000719): Protein kinase domain |
70 |
MCM2 | oncoprotein | 32 | 0.316 | 167.730 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
71 |
MDK | oncoprotein | 3 | 0.667 | 1.000 | PTN_MK_C (PF01091, IPR020090): PTN/MK heparin-binding protein family, C-terminal domain PTN_MK_N (PF05196, IPR020089): PTN/MK heparin-binding protein family, N-terminal domain |
72 |
MEPCE | protein found in more fusions | 8 | 0.571 | 3.050 | Bin3 (PF06859, IPR010675): Bicoid-interacting protein 3 (Bin3) Methyltransf_23 (PF13489): Methyltransferase domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 DLEU7 (PF15760, IPR031510): Leukemia-associated protein 7 |
73 |
MLH1 | suppressor | 9 | 0.417 | 14.217 | DNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mlh1_C (PF16413, IPR032189): DNA mismatch repair protein Mlh1 C-terminus |
74 |
MORF4L1 | interactor | 11 | 0.822 | 2.037 | MRG (PF05712, IPR026541): MRG Fmp27_WPPW (PF10359, IPR019449): RNA pol II promoter Fmp27 protein domain Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain |
75 |
MORF4L2 | interactor | 10 | 0.822 | 2.037 | MRG (PF05712, IPR026541): MRG |
76 |
MRGBP | interactor | 9 | 0.917 | 0.567 | Eaf7 (PF07904, IPR012423): Chromatin modification-related protein EAF7 |
77 |
MYC | oncoprotein | 19 | 0.405 | 45.068 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
78 |
MYH9 | suppressor | 41 | 0.363 | 231.455 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
79 |
MYO18A | interactor | 23 | 0.644 | 32.847 | Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_tail_1 (PF01576, IPR002928): Myosin tail PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 |
80 |
MYO19 | interactor | 19 | 0.766 | 8.363 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
81 |
MYO1C | interactor | 28 | 0.418 | 93.339 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
82 |
MYO5C | interactor | 16 | 0.725 | 10.339 | DIL (PF01843, IPR018444, SM01132): DIL domain DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) ERM (PF00769, IPR011259): Ezrin/radixin/moesin family IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Pilus_CpaD (PF09476, IPR019027): Pilus biogenesis CpaD protein (pilus_cpaD) Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) YtxH (PF12732, IPR024623): YtxH-like protein Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease |
83 |
MYOC | interactor | 6 | 0.800 | 0.667 | IncA (PF04156, IPR007285): IncA protein OLF (PF02191, IPR003112, SM00284): Olfactomedin-like domain |
84 |
NCKAP1 | interactor | 6 | 0.533 | 4.472 | Nckap1 (PF09735, IPR019137): Membrane-associated apoptosis protein |
85 |
NDRG1 | suppressor | 10 | 0.489 | 15.640 | Ndr (PF03096, IPR004142): Ndr family |
86 |
PDLIM7 | interactor | 9 | 0.694 | 4.367 | LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749) |
87 |
PFN2 | interactor | 5 | 0.500 | 2.733 | Profilin (PF00235, IPR005455, SM00392): Profilin |
88 |
PLD1 | suppressor | 1 | 0 | 0 | PH (PF00169, IPR001849, SM00233): PH domain PLDc (PF00614, IPR001736, SM00155): Phospholipase D Active site motif PX (PF00787, IPR001683, SM00312): PX domain PLDc_2 (PF13091, IPR025202): PLD-like domain |
89 |
POU5F1 | oncoprotein | 9 | 0.393 | 9.233 | Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
90 |
PPP1CB | interactor | 27 | 0.538 | 52.856 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
91 |
PPP1CC | oncoprotein | 17 | 0.574 | 21.864 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
92 |
PRSS23 | interactor | 2 | 1.000 | 0 | Trypsin (PF00089, IPR001254, SM00020): Trypsin |
93 |
PSEN2 | oncoprotein | 3 | 1.000 | 0 | Herpes_LMP1 (PF05297, IPR007961): Herpesvirus latent membrane protein 1 (LMP1) Presenilin (PF01080, IPR001108): Presenilin |
94 |
RAN | oncoprotein | 10 | 0.356 | 13.158 | Ras (PF00071, IPR001806, SM00173): Ras family |
95 |
RBX1 | oncoprotein | 7 | 0.400 | 4.567 | zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain |
96 |
RNF2 | interactor | 18 | 0.294 | 60.117 | zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
97 |
RPS6KA5 | interactor | 5 | 0.500 | 1.786 | Choline_kinase (PF01633): Choline/ethanolamine kinase Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein |
98 |
RPS6KB2 | interactor | 14 | 0.495 | 10.089 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
99 |
RUVBL1 | oncoprotein | 24 | 0.352 | 71.101 | TIP49 (PF06068, IPR010339): TIP49 C-terminus |
100 |
RUVBL2 | oncoprotein | 33 | 0.274 | 194.958 | TIP49 (PF06068, IPR010339): TIP49 C-terminus |
101 |
SFN | suppressor | 11 | 0.400 | 14.991 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
102 |
SGF29 | interactor | 1 | 0 | 0 | DUF1325 (PF07039, IPR010750): SGF29 tudor-like domain Filament (PF00038, IPR001664): Intermediate filament protein |
103 |
SH3GL2 | oncoprotein | 3 | 1.000 | 0 | BAR (PF03114, IPR004148, SM00721): BAR domain SH3_2 (PF07653, IPR011511): Variant SH3 domain |
104 |
SHC1 | oncoprotein | 19 | 0.477 | 30.330 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) SH2 (PF00017, IPR000980, SM00252): SH2 domain |
105 |
SP1 | protein found in more fusions | 11 | 0.622 | 5.264 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
106 |
SRPK2 | oncoprotein | 8 | 0.381 | 11.033 | DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Pkinase (PF00069, IPR000719): Protein kinase domain S-antigen (PF05756, IPR008825): S-antigen protein DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) |
107 |
ST3GAL3 | interactor | 1 | 0 | 0 | Glyco_transf_29 (PF00777, IPR001675): Glycosyltransferase family 29 (sialyltransferase) |
108 |
SUZ12 | suppressor | 14 | 0.462 | 18.640 | DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070) VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein |
109 |
TMSB4X | interactor | 3 | 0.667 | 0.667 | Thymosin (PF01290, IPR001152, SM00152): Thymosin beta-4 family |
110 |
TNIK | interactor | 3 | 0.667 | 1.000 | CNH (PF00780, IPR001180, SM00036): CNH domain Pkinase (PF00069, IPR000719): Protein kinase domain Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family DUF3499 (PF12005, IPR021888): Protein of unknown function (DUF3499) CNDH2_M (PF16869): PF16858 AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3 |
111 |
TOPBP1 | protein found in more fusions | 5 | 0.667 | 0.667 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PTCB-BRCT (PF12738, IPR001357): twin BRCT domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
112 |
TRAF2 | interactor | 9 | 0.357 | 12.633 | MATH (PF00917, IPR002083, SM00061): MATH domain Sina (PF03145, IPR018121): Seven in absentia protein family SlyX (PF04102, IPR007236): SlyX zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger) |
113 |
TRAF3IP1 | interactor | 8 | 0.500 | 6.254 | MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 |
114 |
TSGA10 | interactor | 4 | 1.000 | 0 | Bcr-Abl_Oligo (PF09036, IPR015123): Bcr-Abl oncoprotein oligomerisation domain SKA1 (PF07160, IPR009829): Spindle and kinetochore-associated protein 1 DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Pox_A3L (PF05288, IPR007952): Poxvirus A3L Protein DUF4201 (PF13870, IPR025254): Domain of unknown function (DUF4201) PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase |
115 |
UBASH3B | interactor | 12 | 0.764 | 3.577 | His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1) UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain 2_5_RNA_ligase2 (PF13563): 2'-5' RNA ligase superfamily SH3_9 (PF14604, IPR001452): Variant SH3 domain |
116 |
UBE2Q2 | interactor | 4 | 1.000 | 0 | Josephin (PF02099, IPR006155): Josephin RWD (PF05773, IPR006575, SM00591): RWD domain UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme DUF2890 (PF11081, IPR021304): Protein of unknown function (DUF2890) |
117 |
UBL4A | interactor | 12 | 0.333 | 18.705 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
118 |
UCHL5 | oncoprotein | 9 | 0.536 | 6.333 | Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1 |
119 |
VASP | interactor | 8 | 0.667 | 3.515 | ASD2 (PF08687, IPR014799): Apx/Shroom domain ASD2 CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal VASP_tetra (PF08776, IPR014885): VASP tetramerisation domain WH1 (PF00568, IPR000697, SM00461): WH1 domain |
120 |
VCL | oncoprotein | 12 | 0.455 | 13.063 | Vinculin (PF01044, IPR006077): Vinculin family |
121 |
WASL | interactor | 7 | 0.714 | 2.173 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain WH1 (PF00568, IPR000697, SM00461): WH1 domain WH2 (PF02205, IPR003124, SM00246): WH2 motif RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein Caskin-Pro-rich (PF16907): Proline rich region of Caskin proteins |
122 |
WDYHV1 | interactor | 3 | 0.667 | 0.333 | Nt_Gln_amidase (PF09764, IPR023128): N-terminal glutamine amidase |
123 |
WIPF1 | interactor | 5 | 0.700 | 1.567 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal GRP (PF07172, IPR010800): Glycine rich protein family WH2 (PF02205, IPR003124, SM00246): WH2 motif |
124 |
YARS | interactor | 8 | 0.679 | 3.593 | tRNA-synt_1b (PF00579, IPR002305): tRNA synthetases class I (W and Y) tRNA_bind (PF01588, IPR002547): Putative tRNA binding domain |
125 |
YWHAQ | interactor | 23 | 0.356 | 82.903 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |