Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins ACP6 (from a repository: Tue Dec 6 00:22:52 2016)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)21
The number (and %) of the onco-proteins1 (4.76 %)
The number (and %) of the tumor suppressors1 (4.76 %)
Total number of binary PPIs (saturation %)46 (21.90 %)
The number (and %) of affected PPIs21 (45.65 %)
The number of possible different fusions3
PPI diameter2
PPI radius1
The average degree of PPI3.810
Assortativity coefficient-0.4357
The network average Clustering coefficient0.554
The number (and %) of a zero Clustering coefficients5 (23.81 %)
The number (and %) of a zero Betweenness Centrality12 (57.14 %)

ACTIVE INTERACTORS


List of the fusions

Proteins found in more fusions ILK (see 1 fusions); ACP6 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 ACP6parental protein210.105310.167His_Phos_2 (PF00328, IPR000560): Histidine phosphatase superfamily (branch 2)
2 BOLA3interactor60.6002.833BolA (PF01722, IPR002634): BolA-like protein
RNA_binding (PF01877, IPR002739): RNA binding
3 C1QBPinteractor40.6671.000MAM33 (PF02330, IPR003428): Mitochondrial glycoprotein
DUF3053 (PF11254, IPR021413): Protein of unknown function (DUF3053)
4 CYCSinteractor21.0000Cytochrom_C (PF00034, IPR003088): Cytochrome c
5 DHCR7interactor100ERG4_ERG24 (PF01222, IPR001171): Ergosterol biosynthesis ERG4/ERG24 family
6 DHX36interactor21.0000DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
7 ECH1interactor50.5004.000ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase
8 ERHinteractor21.0000ER (PF01133, IPR000781): Enhancer of rudimentary
9 FAM9Binteractor31.0000Cor1 (PF04803, IPR006888): Cor1/Xlr/Xmr conserved region
Spore_coat_CotO (PF14153, IPR025439): Spore coat protein CotO
10 GNG7interactor100G-gamma (PF00631, IPR015898, SM00224): GGL domain
11 ILKsuppressor60.5005.000Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
12 LIMS1interactor31.0000LIM (PF00412, IPR001781, SM00132): LIM domain
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
zf-RRN7 (PF11781, IPR021752): Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7
13 NME4interactor80.33312.167NDK (PF00334, IPR001564, SM00562): Nucleoside diphosphate kinase
14 NRDCinteractor40.6670.500Cnd2 (PF05786, IPR022816): Condensin complex subunit 2
Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
Tom22 (PF04281, IPR005683): Mitochondrial import receptor subunit Tom22
Peptidase_M16_M (PF16187, IPR032632): Middle or third domain of peptidase_M16
15 PMPCAinteractor40.6671.500Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
16 PMPCBinteractor31.0000Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
17 RGS10interactor100FliL (PF03748, IPR005503): Flagellar basal body-associated protein FliL
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
18 RSU1interactor31.0000LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
19 SDHAF3interactor50.6002.833Complex1_LYR_2 (PF13233): Complex1_LYR-like
20 SLC35F6interactor100EamA (PF00892, IPR000620): EamA-like transporter family
SLC35F (PF06027, IPR009262): Solute carrier family 35
21 STOML2oncoprotein100Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
DUF4769 (PF15992, IPR031934): Domain of unknown function (DUF4769)
Band_7_C (PF16200, IPR032435): C-terminal region of band_7

B a c k    t o    T o p ⇑