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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)21
The number (and %) of the onco-proteins1 (4.76 %)
The number (and %) of the tumor suppressors1 (4.76 %)
Total number of binary PPIs (saturation %)46 (21.90 %)
The number (and %) of affected PPIs21 (45.65 %)
The number of possible different fusions3
PPI diameter2
PPI radius1
The average degree of PPI3.810
Assortativity coefficient-0.4357
The network average Clustering coefficient0.554
The number (and %) of a zero Clustering coefficients5 (23.81 %)
The number (and %) of a zero Betweenness Centrality12 (57.14 %)


List of the fusions

Proteins found in more fusions ILK (see 1 fusions); ACP6 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 ACP6parental protein210.105310.167His_Phos_2 (PF00328, IPR000560): Histidine phosphatase superfamily (branch 2)
2 BOLA3interactor60.6002.833BolA (PF01722, IPR002634): BolA-like protein
RNA_binding (PF01877, IPR002739): RNA binding
3 C1QBPinteractor40.6671.000MAM33 (PF02330, IPR003428): Mitochondrial glycoprotein
DUF3053 (PF11254, IPR021413): Protein of unknown function (DUF3053)
4 CYCSinteractor21.0000Cytochrom_C (PF00034, IPR003088): Cytochrome c
5 DHCR7interactor100ERG4_ERG24 (PF01222, IPR001171): Ergosterol biosynthesis ERG4/ERG24 family
6 DHX36interactor21.0000DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
7 ECH1interactor50.5004.000ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase
8 ERHinteractor21.0000ER (PF01133, IPR000781): Enhancer of rudimentary
9 FAM9Binteractor31.0000Cor1 (PF04803, IPR006888): Cor1/Xlr/Xmr conserved region
Spore_coat_CotO (PF14153, IPR025439): Spore coat protein CotO
10 GNG7interactor100G-gamma (PF00631, IPR015898, SM00224): GGL domain
11 ILKsuppressor60.5005.000Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
12 LIMS1interactor31.0000LIM (PF00412, IPR001781, SM00132): LIM domain
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
zf-RRN7 (PF11781, IPR021752): Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7
13 NME4interactor80.33312.167NDK (PF00334, IPR001564, SM00562): Nucleoside diphosphate kinase
14 NRDCinteractor40.6670.500Cnd2 (PF05786, IPR022816): Condensin complex subunit 2
Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
Tom22 (PF04281, IPR005683): Mitochondrial import receptor subunit Tom22
Peptidase_M16_M (PF16187, IPR032632): Middle or third domain of peptidase_M16
15 PMPCAinteractor40.6671.500Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
16 PMPCBinteractor31.0000Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
17 RGS10interactor100FliL (PF03748, IPR005503): Flagellar basal body-associated protein FliL
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
18 RSU1interactor31.0000LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
19 SDHAF3interactor50.6002.833Complex1_LYR_2 (PF13233): Complex1_LYR-like
20 SLC35F6interactor100EamA (PF00892, IPR000620): EamA-like transporter family
SLC35F (PF06027, IPR009262): Solute carrier family 35
21 STOML2oncoprotein100Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
DUF4769 (PF15992, IPR031934): Domain of unknown function (DUF4769)
Band_7_C (PF16200, IPR032435): C-terminal region of band_7

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