Find Fusion Network

Fusion ID:
Protein names:

Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins PELI1, AC024257.1 (from a repository: Tue Mar 31 02:45:38 2020)

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Force Directed
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)26
The number (and %) of the onco-proteins11 (42.31 %)
The number (and %) of the tumor suppressors1 (3.85 %)
Total number of binary PPIs (saturation %)81 (24.92 %)
The number (and %) of affected PPIs24 (29.63 %)
The number of possible different fusions10
PPI diameter2
PPI radiusinf
The average degree of PPI5.000
Assortativity coefficient-0.2479
The network average Clustering coefficient0.662
The number (and %) of a zero Clustering coefficients4 (15.38 %)
The number (and %) of a zero Betweenness Centrality13 (50.00 %)


List of the fusions

PPI for parental proteins: PELI1,AC024257.1 All fusions
Proteins found in more fusions RIPK1 (see 1 fusions); UBE2D2 (see 1 fusions); TRAF6 (see 1 fusions); UBE2N (see 1 fusions); IKBKB (see 2 fusions); BCL6 (see 2 fusions); SRPK2 (see 1 fusions); UBC (see 7 fusions); VAC14 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 PELI1parental protein240.149385.000Pellino (PF04710, IPR006800): Pellino
2 AC024257.1interactor000NA
3 BCL6oncoprotein200BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
DZR (PF12773, IPR025874): Double zinc ribbon
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
4 DEAF1interactor100Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAND (PF01342, IPR000770, SM00258): SAND domain
zf-MYND (PF01753, IPR002893): MYND finger
5 IKBKBprotein found in more fusions60.5003.833FliT (PF05400, IPR008622): Flagellar protein FliT
Glyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain
Pkinase (PF00069, IPR000719): Protein kinase domain
SlyX (PF04102, IPR007236): SlyX
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
6 IL1R1interactor61.0000TIR (PF01582, IPR000157, SM00255): TIR domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
7 IRAK1interactor80.8102.667Death (PF00531, IPR000488, SM00005): Death domain
Pkinase (PF00069, IPR000719): Protein kinase domain
8 IRAK2oncoprotein61.0000Death (PF00531, IPR000488, SM00005): Death domain
Pkinase (PF00069, IPR000719): Protein kinase domain
9 IRAK4interactor61.0000Death (PF00531, IPR000488, SM00005): Death domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
10 IRS1interactor30.6670.500CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
PH (PF00169, IPR001849, SM00233): PH domain
11 MYD88oncoprotein80.7625.000Death (PF00531, IPR000488, SM00005): Death domain
TIR (PF01582, IPR000157, SM00255): TIR domain
12 NR2C2suppressor31.0000Flagellin_N (PF00669, IPR001029): Bacterial flagellin N-terminal helical region
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
13 RIPK1protein found in more fusions50.6671.167Death (PF00531, IPR000488, SM00005): Death domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
RHIM (PF12721, IPR025735): RIP homotypic interaction motif
14 SMAD6interactor21.0000MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
15 SRPK1interactor21.0000FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
Pkinase (PF00069, IPR000719): Protein kinase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
16 SRPK2oncoprotein40.6671.000DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Pkinase (PF00069, IPR000719): Protein kinase domain
S-antigen (PF05756, IPR008825): S-antigen protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
17 TBK1interactor200DUF713 (PF05218, IPR007883): Protein of unknown function (DUF713)
NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
Pkinase (PF00069, IPR000719): Protein kinase domain
18 TRAF6protein found in more fusions150.35254.500SlyX (PF04102, IPR007236): SlyX
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
19 TRIP13interactor31.0000AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
20 UBCprotein found in more fusions90.53610.167ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
21 UBE2D1interactor51.0000UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
22 UBE2D2oncoprotein70.7332.500UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
23 UBE2Iinteractor50.6672.000UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
24 UBE2Nprotein found in more fusions60.8001.167UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
25 UBE2V1interactor50.9000.500UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
26 VAC14oncoprotein31.0000TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain
HEAT (PF02985, IPR000357): HEAT repeat
Vac14_Fig4_bd (PF11916, IPR021841): Vacuolar protein 14 C-terminal Fig4p binding
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region

B a c k    t o    T o p ⇑