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Visible interactions: all affected independent (normal) missing (in fusions) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)204
The number (and %) of the onco-proteins96 (47.06 %)
The number (and %) of the tumor suppressors35 (17.16 %)
Total number of binary PPIs (saturation %)1651 (7.97 %)
The number (and %) of affected PPIs228 (13.81 %)
The number of possible different fusions59
PPI diameter3
PPI radius2
The average degree of PPI15.255
Assortativity coefficient-0.1939
The network average Clustering coefficient0.471
The number (and %) of a zero Clustering coefficients9 (4.41 %)
The number (and %) of a zero Betweenness Centrality26 (12.75 %)

ACTIVE INTERACTORS
MISSING INTERACTORS (in fusions)


List of the fusions

PPI for parental proteins: BCR,ABL1 All fusions
: AJ131466; EU236680; EU216070; S72478; EF423615; M13096; AY789120; DQ912589; KR092000; AM491360; AM491359; DQ912588; EU216066; M19730; AF113911; DQ898313; EU216071; S72479; AM491363; EU394717; EU447303; FN820246; X06418; DQ912590; X07537; AF487522; AM600680; KU234180; FN820225; EU216064; AF533988; AY043457; M25946; EU216059; AM491361; DQ898314; AM491362; EF158045; AJ131467; AM886138;
Proteins found in more fusions ABL2 (see 2 fusions); GRK5 (see 4 fusions); EEF1G (see 1 fusions); RAN/CFTR (see 1 fusions); GAB2 (see 3 fusions); CKAP4 (see 5 fusions); EPS15 (see 1 fusions); CBL (see 1 fusions); HIPK2 (see 1 fusions); GRB2 (see 1 fusions); RAC1 (see 1 fusions); REPS1 (see 1 fusions); MYC (see 1 fusions); YWHAH (see 2 fusions); MDM4 (see 2 fusions); EWSR1 (see 2 fusions); PRKDC (see 3 fusions); PRDX1 (see 1 fusions); PAG1 (see 1 fusions); BCL2L1 (see 1 fusions); YWHAZ (see 1 fusions); PDE4D (see 2 fusions); PIK3R1 (see 1 fusions); SORBS2 (see 4 fusions); PSMA7 (see 2 fusions); PARP1 (see 1 fusions); PCNA (see 1 fusions); PAK2 (see 2 fusions); UBC (see 1 fusions); DDX5 (see 1 fusions); MTOR (see 1 fusions); NEDD4 (see 1 fusions); TP53 (see 3 fusions); AP2M1 (see 3 fusions); BCR/ABL1 (see 183 fusions); YWHAG (see 1 fusions); HSP90AA1 (see 2 fusions); ATR (see 1 fusions); HUWE1 (see 2 fusions); SRPK2 (see 1 fusions); CREB1 (see 2 fusions); PAK4 (see 1 fusions); MAPT (see 1 fusions); ERBB3 (see 2 fusions); NEDD4L (see 3 fusions); TOPBP1 (see 2 fusions); ERBIN (see 4 fusions); SH3KBP1 (see 1 fusions); EGFR (see 2 fusions); STUB1 (see 1 fusions); NEDD9 (see 1 fusions); EPHB2 (see 1 fusions); FOS (see 4 fusions); JAK1 (see 1 fusions); SHC1 (see 1 fusions); DDB1 (see 2 fusions); CBLB (see 4 fusions); HSPA8/HSPD1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 BCRparental protein560.1453915.680Bcr-Abl_Oligo (PF09036, IPR015123): Bcr-Abl oncoprotein oligomerisation domain
C2 (PF00168, IPR000008, SM00239): C2 domain
PH (PF00169, IPR001849, SM00233): PH domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
IQ_SEC7_PH (PF16453, IPR001849): PH domain
2 ABL1parental protein1730.07619351.467Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2
3 ABI1oncoprotein70.5718.965Abi_HHR (PF07815, IPR012849): Abl-interactor HHR
Cytochrom_B558a (PF05038, IPR007732): Cytochrome Cytochrome b558 alpha-subunit
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF4124 (PF13511, IPR025392): Domain of unknown function (DUF4124)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
ATP-synt_ab_Xtn (PF16886, IPR031686): ATPsynthase alpha/beta subunit N-term extension
4 ABI2suppressor40.6670.766Abi_HHR (PF07815, IPR012849): Abl-interactor HHR
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
SH3_9 (PF14604, IPR001452): Variant SH3 domain
TMEM171 (PF15471, IPR029173): Transmembrane protein family 171
ATP-synt_ab_Xtn (PF16886, IPR031686): ATPsynthase alpha/beta subunit N-term extension
5 ABL2oncoprotein210.35879.292Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
NHS (PF15273, IPR024845): NHS-like
6 ACTA1interactor80.5715.649Actin (PF00022, IPR004000, SM00268): Actin
7 AFDNoncoprotein120.36446.340DIL (PF01843, IPR018444, SM01132): DIL domain
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
FHA (PF00498, IPR000253, SM00240): FHA domain
MAP7 (PF05672, IPR008604): MAP7 (E-MAP-115) family
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
Pap_E4 (PF02711, IPR003861): E4 protein
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
ARGLU (PF15346): Arginine and glutamate-rich 1
8 ANKRA2interactor21.0000Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
9 AP2A1interactor130.56436.046Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
Alpha_adaptin_C (PF02296, IPR003164): Alpha adaptin AP2, C-terminal domain
Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain
HEAT_2 (PF13646): HEAT repeats
10 AP2B1interactor120.74212.876Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain
B2-adapt-app_C (PF09066, IPR015151, SM01020): Beta2-adaptin appendage, C-terminal sub-domain
11 AP2M1protein found in more fusions180.49375.936Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family
Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain
12 ARHGAP17interactor100.48933.523BAR (PF03114, IPR004148, SM00721): BAR domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
13 ATMsuppressor160.43830.894FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
HEAT (PF02985, IPR000357): HEAT repeat
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair
ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
14 ATRsuppressor120.52720.017FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
HEAT (PF02985, IPR000357): HEAT repeat
Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1
THP2 (PF09432, IPR018557): Tho complex subunit THP2
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
UME (PF08064, IPR012993, SM00802): UME (NUC010) domain
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
HEAT_EZ (PF13513): HEAT-like repeat
SgrT (PF15894, IPR031767): Inhibitor of glucose uptake transporter SgrT
15 BAG1oncoprotein90.63910.940BAG (PF02179, IPR003103, SM00264): BAG domain
Presenilin (PF01080, IPR001108): Presenilin
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
16 BCAR1oncoprotein200.41662.649Serine_rich (PF08824, IPR014928): Serine rich protein interaction domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF3513 (PF12026, IPR021901): Domain of unknown function (DUF3513)
Caskin1-CID (PF16600): Caskin1 CASK-interaction domain
17 BCL2L1oncoprotein70.4678.257Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family
BH4 (PF02180, IPR003093, SM00265): Bcl-2 homology region 4
18 BMP2Kinteractor50.8001.000Pkinase (PF00069, IPR000719): Protein kinase domain
TCP (PF03634, IPR005333): TCP family transcription factor
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
EOS1 (PF12326, IPR021100): N-glycosylation protein
BMP2K_C (PF15282, IPR028182): BMP-2-inducible protein kinase C-terminus
PNRC (PF15365, IPR028322): Proline-rich nuclear receptor coactivator
FAM60A (PF15396, IPR026065): Protein Family FAM60A
19 BRCA1suppressor400.212403.127BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
20 CABLES2interactor21.0000Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
21 CASP9oncoprotein50.7002.167CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
Peptidase_C14 (PF00656, IPR011600): Caspase domain
22 CATsuppressor60.6003.060Catalase (PF00199, IPR011614, SM01060): Catalase
Catalase-rel (PF06628, IPR010582): Catalase-related immune-responsive
23 CBLsuppressor530.263747.175Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1
Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain
Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
24 CBLBoncoprotein190.58829.701Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1
Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain
Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
PRIMA1 (PF16101): Proline-rich membrane anchor 1
25 CCDC183interactor100MRP-63 (PF14978, IPR016576): Mitochondrial ribosome protein 63
26 CCND2oncoprotein30.6670.400Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
27 CDC42oncoprotein170.158143.307Ras (PF00071, IPR001806, SM00173): Ras family
28 CDK1oncoprotein140.44928.494Pkinase (PF00069, IPR000719): Protein kinase domain
29 CDKN1Bsuppressor150.37164.169CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
Multi-haem_cyto (PF13447): Seven times multi-haem cytochrome CxxCH
30 CDONoncoprotein21.0000fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Glyco_hydro_76 (PF03663, IPR005198): Glycosyl hydrolase family 76
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Fer4_2 (PF12797, IPR001450): 4Fe-4S binding domain
Ig_3 (PF13927): Immunoglobulin domain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
31 CEP128interactor140.19893.762DUF1129 (PF06570, IPR009214): Protein of unknown function (DUF1129)
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
SpoOE-like (PF09388, IPR018540): Spo0E like sporulation regulatory protein
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
TraF_2 (PF13729, IPR032811): F plasmid transfer operon, TraF, protein
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
HAUS6_N (PF14661, IPR028163): HAUS augmin-like complex subunit 6 N-terminus
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
32 CFTRsuppressor160.31460.678ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain
CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain
33 CKAP4protein found in more fusions100.4178.960DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
FPP (PF05911, IPR008587): Filament-like plant protein, long coiled-coil
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
34 CREB1oncoprotein90.5366.407bZIP_1 (PF00170, IPR004827): bZIP transcription factor
pKID (PF02173, IPR003102): pKID domain
DUF4988 (PF16378, IPR032149): Domain of unknown function
35 CRKoncoprotein500.241659.829SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
36 CRKLoncoprotein270.379191.083SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
37 CSNK2A2interactor90.47219.172Pkinase (PF00069, IPR000719): Protein kinase domain
38 CTNNB1oncoprotein260.277183.742Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
39 DDB1protein found in more fusions190.34060.149CPSF_A (PF03178, IPR004871): CPSF A subunit region
MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
40 DDX5oncoprotein160.45724.208DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
P68HR (PF08061, IPR012587): P68HR (NUC004) repeat
ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
41 DOK1suppressor200.55655.616IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
PH (PF00169, IPR001849, SM00233): PH domain
42 DOK2suppressor90.69410.547IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
PH (PF00169, IPR001849, SM00233): PH domain
43 DRG1interactor70.4764.092MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase
TGS (PF02824, IPR004095): TGS domain
MMR_HSR1_Xtn (PF16897, IPR031662): C-terminal region of MMR_HSR1 domain
44 EEF1Gprotein found in more fusions130.45521.325EF1G (PF00647, IPR001662): Elongation factor 1 gamma, conserved domain
GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain
GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain
SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein
45 EGFRoncoprotein730.2041272.472Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
46 EIF2Ainteractor40.8330.396Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like
eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
47 EPHA3suppressor41.0000EGF_2 (PF07974, IPR013111): EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
48 EPHB2suppressor80.47610.360EGF_2 (PF07974, IPR013111): EGF-like domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
49 EPS15oncoprotein180.49342.616Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
50 ERBB2oncoprotein310.384132.313Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
51 ERBB3oncoprotein250.42861.373Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
52 ERBB4suppressor180.49322.872Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
DUF3951 (PF13131, IPR025028): Protein of unknown function (DUF3951)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
53 ERBINoncoprotein80.6195.995LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
54 ERCC3oncoprotein50.5009.543ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit
DUF2748 (PF10871, IPR020183): Protein of unknown function (DUF2748)
Helicase_C_3 (PF13625, IPR032830): Helicase conserved C-terminal domain
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
ERCC3_RAD25_C (PF16203, IPR032438): ERCC3/RAD25/XPB C-terminal helicase
55 EVLoncoprotein60.6001.351VASP_tetra (PF08776, IPR014885): VASP tetramerisation domain
WH1 (PF00568, IPR000697, SM00461): WH1 domain
56 EWSR1oncoprotein250.217199.767RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
57 FESoncoprotein90.42911.159FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Remorin_C (PF03763, IPR005516): Remorin, C-terminal region
SH2 (PF00017, IPR000980, SM00252): SH2 domain
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
58 FGFR1OPoncoprotein80.38127.223FOP_dimer (PF09398, IPR018993): FOP N terminal dimerisation domain
59 FOSoncoprotein70.4673.262bZIP_1 (PF00170, IPR004827): bZIP transcription factor
60 FUSsuppressor240.275139.046Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Limkain-b1 (PF11608, IPR024582): Limkain b1
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
61 GAB2oncoprotein180.40438.924PH (PF00169, IPR001849, SM00233): PH domain
Pheromone (PF08015, IPR012597): Fungal mating-type pheromone
62 GAB3interactor31.0000PH (PF00169, IPR001849, SM00233): PH domain
63 GABRR1interactor200Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
64 GPX1oncoprotein30.3336.361GSHPx (PF00255, IPR000889): Glutathione peroxidase
65 GRAP2interactor70.5714.819NADH_dhqG_C (PF09326, IPR015405): NADH-ubiquinone oxidoreductase subunit G, C-terminal
SH2 (PF00017, IPR000980, SM00252): SH2 domain
DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076)
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
66 GRB10oncoprotein90.44419.293BPS (PF08947, IPR015042): BPS (Between PH and SH2)
PH (PF00169, IPR001849, SM00233): PH domain
RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
Argos (PF11581, IPR021633): Antagonist of EGFR signalling, Argos
67 GRB2oncoprotein670.2231176.590SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
68 GRK5protein found in more fusions130.21234.620Pkinase (PF00069, IPR000719): Protein kinase domain
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
69 GTF2F1interactor80.5717.342TFIIF_alpha (PF05793, IPR008851): Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)
70 HCKoncoprotein180.366156.930Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
71 HIF1Asuppressor180.41249.060Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein
HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
PAS (PF00989, IPR013767, SM00091): PAS fold
PAS_3 (PF08447, IPR013655): PAS fold
HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
72 HIPK2suppressor60.7004.307Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
73 HNRNPMinteractor140.44035.206RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M
Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region
74 HOXA9oncoprotein21.0000Hox9_act (PF04617, IPR006711): Hox9 activation region
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
75 HSP90AA1oncoprotein430.257538.906HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
76 HSPA4interactor280.320206.234Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region
HSP70 (PF00012, IPR013126): Hsp70 protein
TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
77 HSPA8oncoprotein360.360230.609HSP70 (PF00012, IPR013126): Hsp70 protein
78 HSPD1suppressor150.51437.213Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
79 HSPE1interactor70.33356.526Cpn10 (PF00166, IPR020818, SM00883): Chaperonin 10 Kd subunit
80 HUWE1oncoprotein330.286233.043BUD22 (PF09073, IPR015158): BUD22
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation
HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Nop14 (PF04147, IPR007276): Nop14-like family
PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
WWE (PF02825, IPR004170, SM00678): WWE domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
81 IGSF21interactor100C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
82 IL3oncoprotein100IL3 (PF02059, IPR002183): Interleukin-3
83 ILF3oncoprotein120.37958.536dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
DZF (PF07528, IPR006561, SM00572): DZF domain
84 INPP5Dinteractor140.57121.363Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
SH2 (PF00017, IPR000980, SM00252): SH2 domain
85 INPPL1oncoprotein200.52144.843Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SH2 (PF00017, IPR000980, SM00252): SH2 domain
86 JAK1oncoprotein150.45124.170FERM_M (PF00373, IPR019748): FERM central domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
87 JUNoncoprotein220.286100.936bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
88 KIToncoprotein170.46396.476ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
89 LARSinteractor80.39321.460Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA
tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V)
90 LATS2suppressor140.26968.084Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
91 LNX1interactor60.6005.883PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
92 LRRC59interactor70.5245.810Hid1 (PF12722): High-temperature-induced dauer-formation protein
LRR_8 (PF13855, IPR001611): Leucine rich repeat
DUF4366 (PF14283, IPR025376): Domain of unknown function (DUF4366)
93 LRRK1interactor120.43640.728Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
Pkinase (PF00069, IPR000719): Protein kinase domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
COR (PF16095, IPR032171): C-terminal of Roc, COR, domain
94 MAPTprotein found in more fusions150.52713.767Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat
95 MAVSinteractor50.6671.134Ice_nucleation (PF00818, IPR000258): Ice nucleation protein repeat
CARD_2 (PF16739, IPR031964): Caspase recruitment domain
96 MBPinteractor50.4003.668Myelin_MBP (PF01669, IPR000548): Myelin basic protein
97 MDM2oncoprotein400.189434.075Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region
Presenilin (PF01080, IPR001108): Presenilin
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
98 MDM4oncoprotein170.46731.226zf-FLZ (PF04570, IPR007650): zinc-finger of the FCS-type, C2-C2
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
99 MICAL1interactor60.7332.145CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DAO (PF01266, IPR006076): FAD dependent oxidoreductase
FAD_binding_3 (PF01494, IPR002938): FAD binding domain
LIM (PF00412, IPR001781, SM00132): LIM domain
DUF3585 (PF12130, IPR022735): Protein of unknown function (DUF3585)
NAD_binding_7 (PF13241, IPR006367): Putative NAD(P)-binding
100 MSH5interactor21.0000MutS_V (PF00488, IPR000432, SM00534): MutS domain V
MutS_III (PF05192, IPR007696, SM00533): MutS domain III
101 MTORoncoprotein150.39630.959DUF1104 (PF06518, IPR009488): Protein of unknown function (DUF1104)
EPSP_synthase (PF00275, IPR001986): EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
HEAT (PF02985, IPR000357): HEAT repeat
FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain
V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
TPR_19 (PF14559): Tetratricopeptide repeat
102 MUC1oncoprotein110.5458.122SEA (PF01390, IPR000082, SM00200): SEA domain
Shisa (PF13908, IPR026910): Wnt and FGF inhibitory regulator
Collectrin (PF16959, IPR031588): Renal amino acid transporter
103 MYConcoprotein330.208324.550HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
104 NAA25interactor31.0000BTAD (PF03704, IPR005158, SM01043): Bacterial transcriptional activator domain
NatB_MDM20 (PF09797, IPR019183): N-acetyltransferase B complex (NatB) non catalytic subunit
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
Alkyl_sulf_dimr (PF14863, IPR029228): Alkyl sulfatase dimerisation
105 NARSinteractor70.38117.704tRNA-synt_2 (PF00152, IPR004364): tRNA synthetases class II (D, K and N)
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
106 NCK1oncoprotein200.40062.805SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
107 NCOA3oncoprotein110.25537.611DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518)
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator
PAS (PF00989, IPR013767, SM00091): PAS fold
PAS_3 (PF08447, IPR013655): PAS fold
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
SRC-1 (PF08832, IPR014935): Steroid receptor coactivator
PAS_11 (PF14598): PAS domain
DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927)
NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein
AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
108 NEDD4suppressor230.247163.770Rota_NS26 (PF01525, IPR002512): Rotavirus NS26
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
109 NEDD4Lsuppressor130.6217.504WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
110 NEDD9protein found in more fusions100.50013.236Serine_rich (PF08824, IPR014928): Serine rich protein interaction domain
DUF3513 (PF12026, IPR021901): Domain of unknown function (DUF3513)
SH3_9 (PF14604, IPR001452): Variant SH3 domain
111 NFKBIAoncoprotein120.25866.935Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
112 NINLinteractor80.32125.116PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat
TBCA (PF02970, IPR004226): Tubulin binding cofactor A
DUF2389 (PF09493, IPR012663): Tryptophan-rich protein (DUF2389)
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
FAM184 (PF15665): Family with sequence similarity 184, A and B
TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
113 NTRK1oncoprotein850.1412479.668I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
114 PAG1protein found in more fusions70.8670.367PAG (PF15347, IPR032748): Phosphoprotein associated with glycosphingolipid-enriched
115 PAK2protein found in more fusions150.40747.371PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
116 PAK4protein found in more fusions200.292125.453PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
117 PARK2suppressor300.227195.671IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
118 PARP1suppressor150.54918.160BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain
PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain
PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain
WGR (PF05406, IPR008893, SM00773): WGR domain
zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
119 PCNAoncoprotein190.39263.284PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain
PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain
120 PDE4Doncoprotein70.6002.379Na_trans_assoc (PF06512, IPR010526): Sodium ion transport-associated
PDEase_I (PF00233, IPR002073): 3'5'-cyclic nucleotide phosphodiesterase
121 PFDN4interactor21.0000Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
122 PIK3CGoncoprotein21.0000Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
PI3K_C2 (PF00792, IPR002420, SM00142): Phosphoinositide 3-kinase C2
PI3K_rbd (PF00794, IPR000341, SM00144): PI3-kinase family, ras-binding domain
PI3Ka (PF00613, IPR001263, SM00145): Phosphoinositide 3-kinase family, accessory domain (PIK domain)
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
DUF3244 (PF11589, IPR021638): Domain of unknown function (DUF3244)
DUF4135 (PF13575, IPR025410): Domain of unknown function (DUF4135)
123 PIK3R1oncoprotein380.335278.126RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain
124 PIK3R2oncoprotein210.58648.831RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain
125 PLCG1oncoprotein220.403127.240C2 (PF00168, IPR000008, SM00239): C2 domain
PH (PF00169, IPR001849, SM00233): PH domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
PI-PLC-X (PF00388, IPR000909, SM00148): Phosphatidylinositol-specific phospholipase C, X domain
PI-PLC-Y (PF00387, IPR001711, SM00149): Phosphatidylinositol-specific phospholipase C, Y domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
PH_12 (PF16457, IPR001849): Pleckstrin homology domain
126 PPM1Binteractor60.6003.128PP2C (PF00481, IPR001932): Protein phosphatase 2C
PP2C_C (PF07830, IPR012911, SM00332): Protein serine/threonine phosphatase 2C, C-terminal domain
127 PRDX1oncoprotein150.37438.802AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
128 PRKCZinteractor140.41025.589PB1 (PF00564, IPR000270, SM00666): PB1 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
129 PRKDCprotein found in more fusions240.352121.063FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
NUC194 (PF08163, IPR012582): NUC194 domain
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
130 PSMA4interactor100.46713.462Proteasome (PF00227, IPR001353): Proteasome subunit
U79_P34 (PF03064, IPR004138): HSV U79 / HCMV P34
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
131 PSMA7protein found in more fusions170.41744.402Proteasome (PF00227, IPR001353): Proteasome subunit
Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
132 PSMD4interactor140.58214.036UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
133 PSTPIP1interactor100ABATE (PF07336, IPR010852): Putative stress-induced transcription regulator
FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain
WXG100 (PF06013, IPR010310): Proteins of 100 residues with WXG
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
134 PTGES3interactor100.55627.368CS (PF04969, IPR007052): CS domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
135 PTPN6suppressor130.57734.433SH2 (PF00017, IPR000980, SM00252): SH2 domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
PolyA_pol_arg_C (PF12626, IPR025866): Polymerase A arginine-rich C-terminus
136 PXNoncoprotein130.48730.349LIM (PF00412, IPR001781, SM00132): LIM domain
Paxillin (PF03535): Paxillin family
137 RAC1oncoprotein100.08337.102Ras (PF00071, IPR001806, SM00173): Ras family
138 RAD51interactor80.6199.155Rad51 (PF08423, IPR013632): Rad51
HHH_5 (PF14520): Helix-hairpin-helix domain
139 RAD9Aoncoprotein50.5003.067Rad9 (PF04139, IPR007268): Rad9
140 RANoncoprotein90.36128.033Ras (PF00071, IPR001806, SM00173): Ras family
141 RAPGEF1oncoprotein100.7334.382RasGEF (PF00617, IPR001895, SM00147): RasGEF domain
RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif
142 RASA1oncoprotein210.36283.759C2 (PF00168, IPR000008, SM00239): C2 domain
PH (PF00169, IPR001849, SM00233): PH domain
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
143 RB1suppressor190.345127.061RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain
RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain
Rb_C (PF08934, IPR015030): Rb C-terminal domain
DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592)
144 REPS1protein found in more fusions50.3336.746Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
MCLC (PF05934, IPR009231): Mid-1-related chloride channel (MCLC)
DUF3123 (PF11321, IPR021470): Protein of unknown function (DUF3123)
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
145 RFX1interactor21.0000Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
RFX1_trans_act (PF04589, IPR007668): RFX1 transcription activation region
RFX_DNA_binding (PF02257, IPR003150): RFX DNA-binding domain
146 RHOAsuppressor60.20012.700Ras (PF00071, IPR001806, SM00173): Ras family
147 RPL37interactor40.6671.162Ribosomal_L37e (PF01907, IPR001569): Ribosomal protein L37e
148 RPLP1interactor50.5002.650Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
149 RPS21interactor40.6672.000Ribosomal_S21e (PF01249, IPR001931): Ribosomal protein S21e
150 RSPH9interactor100Radial_spoke (PF04712, IPR006802): Radial spokehead-like protein
151 RTFDC1interactor21.0000Rtf2 (PF04641, IPR027799): Rtf2 RING-finger
152 RYBPinteractor60.53311.046DUF11 (PF01345, IPR001434): Domain of unknown function DUF11
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase (PF00069, IPR000719): Protein kinase domain
PPAK (PF02818, IPR004168): PPAK motif
Titin_Z (PF09042, IPR015129): Titin Z
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Y_Y_Y (PF07495, IPR011123): Y_Y_Y domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
Ig_3 (PF13927): Immunoglobulin domain
153 SEC13interactor60.4005.026WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein
154 SFNsuppressor270.286163.49114-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
155 SH3BP1interactor40.6671.049BAR (PF03114, IPR004148, SM00721): BAR domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting
156 SH3KBP1protein found in more fusions210.43777.901Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein
SH3_9 (PF14604, IPR001452): Variant SH3 domain
157 SHBinteractor90.7222.211Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
SH2 (PF00017, IPR000980, SM00252): SH2 domain
Period_C (PF12114, IPR022728): Period protein 2/3C-terminal region
158 SHC1oncoprotein410.323332.750PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
SH2 (PF00017, IPR000980, SM00252): SH2 domain
159 SHDinteractor100SH2 (PF00017, IPR000980, SM00252): SH2 domain
160 SHEinteractor100SH2 (PF00017, IPR000980, SM00252): SH2 domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
161 SLC9A2oncoprotein40.6671.792Na_H_Exchanger (PF00999, IPR006153): Sodium/hydrogen exchanger family
Sigma_reg_N (PF13800, IPR029101): Sigma factor regulator N-terminal
NEXCaM_BD (PF16644, IPR032103): Regulatory region of Na+/H+ exchanger NHE binds to calmodulin
162 SOCS1suppressor150.48638.468SH2 (PF00017, IPR000980, SM00252): SH2 domain
SOCS_box (PF07525, IPR001496): SOCS box
163 SOCS3suppressor60.6003.062SH2 (PF00017, IPR000980, SM00252): SH2 domain
SOCS_box (PF07525, IPR001496): SOCS box
164 SORBS1interactor100.46724.327SH3_2 (PF07653, IPR011511): Variant SH3 domain
Sorb (PF02208, IPR003127, SM00459): Sorbin homologous domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
SCAB-ABD (PF16711, IPR032012): Actin-binding domain of plant-specific actin-binding protein
165 SORBS2oncoprotein120.47320.247Sorb (PF02208, IPR003127, SM00459): Sorbin homologous domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
166 SOS1oncoprotein190.48056.611Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
PH (PF00169, IPR001849, SM00233): PH domain
RasGEF (PF00617, IPR001895, SM00147): RasGEF domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif
167 SPAG9interactor31.0000DUF501 (PF04417, IPR007511): Protein of unknown function (DUF501)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
IncA (PF04156, IPR007285): IncA protein
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
UPF0449 (PF15136, IPR028227): Uncharacterised protein family UPF0449
JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
168 SPRR2Ainteractor40.8330.167SPRR2 (PF14820, IPR029142): Small proline-rich 2
169 SPTA1interactor70.5248.003EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
170 SPTAN1oncoprotein130.38542.464EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
Tetrabrachion (PF11401, IPR021535): Tetrabrachion
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
171 SRConcoprotein480.184790.962Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
172 SRPK2oncoprotein120.30967.820DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Pkinase (PF00069, IPR000719): Protein kinase domain
S-antigen (PF05756, IPR008825): S-antigen protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
173 ST5suppressor21.0000dDENN (PF03455, IPR005112, SM00801): dDENN domain
DENN (PF02141, IPR001194, SM00799): DENN (AEX-3) domain
DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
uDENN (PF03456, IPR005113, SM00800): uDENN domain
SEEEED (PF14797, IPR029394): Serine-rich region of AP3B1, clathrin-adaptor complex
174 STK4oncoprotein70.4674.851Pkinase (PF00069, IPR000719): Protein kinase domain
Mst1_SARAH (PF11629, IPR024205): C terminal SARAH domain of Mst1
DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611)
175 STON2interactor31.0000Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family
Stonin2_N (PF12016, IPR022699): Stonin 2
176 STUB1suppressor230.42090.108U-box (PF04564, IPR003613, SM00504): U-box domain
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_20 (PF14561): Tetratricopeptide repeat
177 SUB1interactor40.6670.200Dehydrin (PF00257, IPR000167): Dehydrin
PC4 (PF02229, IPR003173): Transcriptional Coactivator p15 (PC4)
178 TERF1interactor210.232125.447TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
179 TOPBP1protein found in more fusions80.6194.759BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
PTCB-BRCT (PF12738, IPR001357): twin BRCT domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
180 TP53suppressor580.1671428.318DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
181 TP73suppressor140.41023.861P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
182 TSG101suppressor130.40938.071APG6 (PF04111, IPR007243): Autophagy protein Apg6
Laminin_II (PF06009, IPR010307): Laminin Domain II
UEV (PF05743, IPR008883): UEV domain
Vps23_core (PF09454, IPR017916): Vps23 core domain
183 TUBinteractor21.0000Tub (PF01167, IPR000007): Tub family
Tub_N (PF16322, IPR005398): Tubby N-terminal
184 UBASH3Binteractor200.50367.912His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1)
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
2_5_RNA_ligase2 (PF13563): 2'-5' RNA ligase superfamily
SH3_9 (PF14604, IPR001452): Variant SH3 domain
185 UBCprotein found in more fusions460.240688.636ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
186 UNC119interactor40.3337.617GMP_PDE_delta (PF05351, IPR008015): GMP-PDE, delta subunit
187 USP7oncoprotein130.53012.390MATH (PF00917, IPR002083, SM00061): MATH domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7
USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal
188 VAV1oncoprotein190.40485.726PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain
189 VPS28interactor40.8330.100VPS28 (PF03997, IPR007143): VPS28 protein
190 WASF1interactor50.30017.954Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
WH2 (PF02205, IPR003124, SM00246): WH2 motif
191 WDR48suppressor70.6198.380WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF3337 (PF11816, IPR021772): Domain of unknown function (DUF3337)
192 WRNIP1interactor70.6003.291AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
RuvB_N (PF05496, IPR008824): Holliday junction DNA helicase ruvB N-terminus
Sgf11 (PF08209, IPR013246): Sgf11 (transcriptional regulation protein)
MgsA_C (PF12002, IPR021886): MgsA AAA+ ATPase C terminal
AAA_assoc_2 (PF16193, IPR032423): AAA C-terminal domain
193 XPO1interactor520.1581167.004CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
194 XRCC6oncoprotein170.35053.154Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
SAP (PF02037, IPR003034, SM00513): SAP domain
195 YAP1suppressor160.39234.998Bindin (PF02084, IPR000775): Bindin
WW (PF00397, IPR001202, SM00456): WW domain
GspL_C (PF12693, IPR025691): GspL periplasmic domain
FAM181 (PF15238, IPR029359): FAM181
196 YTHDC1interactor31.0000DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
YTH (PF04146, IPR007275): YT521-B-like domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
TFB6 (PF17110, IPR031349): Subunit 11 of the general transcription factor TFIIH
197 YWHABinteractor260.400106.27814-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
Virulence_fact (PF13769, IPR025989): Virulence factor
198 YWHAEoncoprotein280.349142.12914-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
199 YWHAGprotein found in more fusions260.41399.35714-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
200 YWHAHprotein found in more fusions200.49746.26714-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
201 YWHAQinteractor320.319194.26414-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
202 YWHAZprotein found in more fusions330.367145.66914-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
203 ZAP70interactor180.58123.055Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
204 ZDHHC16interactor100DUF1049 (PF06305, IPR010445): Protein of unknown function (DUF1049)
NS3_envE (PF02723, IPR003873): Non-structural protein NS3/Small envelope protein E
zf-DHHC (PF01529, IPR001594): DHHC palmitoyltransferase

B a c k    t o    T o p ⇑


List of missing interactors (in fusions)

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ABI1oncoproteinAbi_HHR (PF07815, IPR012849): Abl-interactor HHR
Cytochrom_B558a (PF05038, IPR007732): Cytochrome Cytochrome b558 alpha-subunit
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF4124 (PF13511, IPR025392): Domain of unknown function (DUF4124)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
ATP-synt_ab_Xtn (PF16886, IPR031686): ATPsynthase alpha/beta subunit N-term extension
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
2 ABI2suppressorAbi_HHR (PF07815, IPR012849): Abl-interactor HHR
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
SH3_9 (PF14604, IPR001452): Variant SH3 domain
TMEM171 (PF15471, IPR029173): Transmembrane protein family 171
ATP-synt_ab_Xtn (PF16886, IPR031686): ATPsynthase alpha/beta subunit N-term extension
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
3 ABL1parental proteinPkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2
AF113911, AF487522, AF533988, AJ131466, AJ131467, AM491359, AM491360, AM491361, AM491362, AM491363, AM600680, AM886138, AY043457, AY789120, DQ898313, DQ898314, DQ912588, DQ912589, DQ912590, EF158045, EF423615, EU216059, EU216064, EU216066, EU216070, EU216071, EU236680, EU394717, EU447303, FN820225, FN820246, KR092000, KU234180, M13096, M19730, M25946, S72478, S72479, X06418, X07537
4 ABL2oncoproteinPkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
NHS (PF15273, IPR024845): NHS-like
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
5 ACTA1interactorActin (PF00022, IPR004000, SM00268): ActinAF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
6 ANKRA2interactorAnk_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
7 AP2A1interactorAdaptin_N (PF01602, IPR002553): Adaptin N terminal region
Alpha_adaptin_C (PF02296, IPR003164): Alpha adaptin AP2, C-terminal domain
Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain
HEAT_2 (PF13646): HEAT repeats
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
8 AP2B1interactorAdaptin_N (PF01602, IPR002553): Adaptin N terminal region
Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain
B2-adapt-app_C (PF09066, IPR015151, SM01020): Beta2-adaptin appendage, C-terminal sub-domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
9 ARHGAP17interactorBAR (PF03114, IPR004148, SM00721): BAR domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
10 ATMsuppressorFAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
HEAT (PF02985, IPR000357): HEAT repeat
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair
ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
11 ATRsuppressorFAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
HEAT (PF02985, IPR000357): HEAT repeat
Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1
THP2 (PF09432, IPR018557): Tho complex subunit THP2
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
UME (PF08064, IPR012993, SM00802): UME (NUC010) domain
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
HEAT_EZ (PF13513): HEAT-like repeat
SgrT (PF15894, IPR031767): Inhibitor of glucose uptake transporter SgrT
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
12 BAG1oncoproteinBAG (PF02179, IPR003103, SM00264): BAG domain
Presenilin (PF01080, IPR001108): Presenilin
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
13 BCAR1oncoproteinSerine_rich (PF08824, IPR014928): Serine rich protein interaction domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF3513 (PF12026, IPR021901): Domain of unknown function (DUF3513)
Caskin1-CID (PF16600): Caskin1 CASK-interaction domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
14 BCL2L1oncoproteinBcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family
BH4 (PF02180, IPR003093, SM00265): Bcl-2 homology region 4
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
15 BCRparental proteinBcr-Abl_Oligo (PF09036, IPR015123): Bcr-Abl oncoprotein oligomerisation domain
C2 (PF00168, IPR000008, SM00239): C2 domain
PH (PF00169, IPR001849, SM00233): PH domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
IQ_SEC7_PH (PF16453, IPR001849): PH domain
AF113911, AF487522, AF533988, AJ131466, AJ131467, AM491359, AM491360, AM491361, AM491362, AM491363, AM600680, AM886138, AY043457, AY789120, DQ898313, DQ898314, DQ912588, DQ912589, DQ912590, EF158045, EF423615, EU216059, EU216064, EU216066, EU216070, EU216071, EU236680, EU394717, EU447303, FN820225, FN820246, KR092000, KU234180, M13096, M19730, M25946, S72478, S72479, X06418, X07537
16 BMP2KinteractorPkinase (PF00069, IPR000719): Protein kinase domain
TCP (PF03634, IPR005333): TCP family transcription factor
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
EOS1 (PF12326, IPR021100): N-glycosylation protein
BMP2K_C (PF15282, IPR028182): BMP-2-inducible protein kinase C-terminus
PNRC (PF15365, IPR028322): Proline-rich nuclear receptor coactivator
FAM60A (PF15396, IPR026065): Protein Family FAM60A
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
17 BRCA1suppressorBRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
18 CABLES2interactorCyclin_N (PF00134, IPR006671): Cyclin, N-terminal domainAF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
19 CASP9oncoproteinCARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
Peptidase_C14 (PF00656, IPR011600): Caspase domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
20 CATsuppressorCatalase (PF00199, IPR011614, SM01060): Catalase
Catalase-rel (PF06628, IPR010582): Catalase-related immune-responsive
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
21 CBLBoncoproteinCbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1
Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain
Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
PRIMA1 (PF16101): Proline-rich membrane anchor 1
AF533988
22 CCDC183interactorMRP-63 (PF14978, IPR016576): Mitochondrial ribosome protein 63AF113911, AF533988, AM491359, AM491361, AM600680, AY789120, DQ898313, DQ912588, EU216059, EU216064, EU216070, EU447303, M19730, S72479, X06418, X07537
23 CCND2oncoproteinCyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
24 CDC42oncoproteinRas (PF00071, IPR001806, SM00173): Ras familyAF533988
25 CDK1oncoproteinPkinase (PF00069, IPR000719): Protein kinase domainAF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
26 CDKN1BsuppressorCDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
Multi-haem_cyto (PF13447): Seven times multi-haem cytochrome CxxCH
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
27 CDONoncoproteinfn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Glyco_hydro_76 (PF03663, IPR005198): Glycosyl hydrolase family 76
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Fer4_2 (PF12797, IPR001450): 4Fe-4S binding domain
Ig_3 (PF13927): Immunoglobulin domain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
28 CEP128interactorDUF1129 (PF06570, IPR009214): Protein of unknown function (DUF1129)
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
SpoOE-like (PF09388, IPR018540): Spo0E like sporulation regulatory protein
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
TraF_2 (PF13729, IPR032811): F plasmid transfer operon, TraF, protein
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
HAUS6_N (PF14661, IPR028163): HAUS augmin-like complex subunit 6 N-terminus
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
AM600680, DQ898313, DQ912588
29 CFTRsuppressorABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain
CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain
AM600680, AY789120, DQ898313, DQ912588, EU216059, EU216064, EU216070, EU447303
30 CKAP4interactorDUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
FPP (PF05911, IPR008587): Filament-like plant protein, long coiled-coil
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
31 CREB1oncoproteinbZIP_1 (PF00170, IPR004827): bZIP transcription factor
pKID (PF02173, IPR003102): pKID domain
DUF4988 (PF16378, IPR032149): Domain of unknown function
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
32 CTNNB1oncoproteinArm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
33 DDB1interactorCPSF_A (PF03178, IPR004871): CPSF A subunit region
MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
34 DDX5oncoproteinDEAD (PF00270, IPR011545): DEAD/DEAH box helicase
P68HR (PF08061, IPR012587): P68HR (NUC004) repeat
ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
35 DOK2suppressorIRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
PH (PF00169, IPR001849, SM00233): PH domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
36 DRG1interactorMMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase
TGS (PF02824, IPR004095): TGS domain
MMR_HSR1_Xtn (PF16897, IPR031662): C-terminal region of MMR_HSR1 domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
37 EEF1GinteractorEF1G (PF00647, IPR001662): Elongation factor 1 gamma, conserved domain
GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain
GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain
SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
38 EGFRoncoproteinFurin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
39 EIF2AinteractorBap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like
eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
40 EPHA3suppressorEGF_2 (PF07974, IPR013111): EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
41 EPHB2suppressorEGF_2 (PF07974, IPR013111): EGF-like domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
42 EPS15oncoproteinReo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
AF533988
43 ERBB2oncoproteinFurin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
44 ERBB3oncoproteinFurin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
45 ERBB4suppressorFurin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
DUF3951 (PF13131, IPR025028): Protein of unknown function (DUF3951)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
46 ERCC3oncoproteinResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit
DUF2748 (PF10871, IPR020183): Protein of unknown function (DUF2748)
Helicase_C_3 (PF13625, IPR032830): Helicase conserved C-terminal domain
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
ERCC3_RAD25_C (PF16203, IPR032438): ERCC3/RAD25/XPB C-terminal helicase
AM491359, AM600680, AY789120, DQ898313, DQ912588, EU216059, EU216064, EU216070, EU447303
47 EVLoncoproteinVASP_tetra (PF08776, IPR014885): VASP tetramerisation domain
WH1 (PF00568, IPR000697, SM00461): WH1 domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
48 EWSR1oncoproteinRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
49 FGFR1OPoncoproteinFOP_dimer (PF09398, IPR018993): FOP N terminal dimerisation domainAF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
50 FOSoncoproteinbZIP_1 (PF00170, IPR004827): bZIP transcription factorAF533988, AM600680, DQ898313, DQ898314, DQ912588, DQ912589, DQ912590, FN820225, FN820246
51 FUSsuppressorHerpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Limkain-b1 (PF11608, IPR024582): Limkain b1
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
52 GAB3interactorPH (PF00169, IPR001849, SM00233): PH domainAF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
53 GPX1oncoproteinGSHPx (PF00255, IPR000889): Glutathione peroxidaseAF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
54 GRAP2interactorNADH_dhqG_C (PF09326, IPR015405): NADH-ubiquinone oxidoreductase subunit G, C-terminal
SH2 (PF00017, IPR000980, SM00252): SH2 domain
DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076)
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
55 GRB10oncoproteinBPS (PF08947, IPR015042): BPS (Between PH and SH2)
PH (PF00169, IPR001849, SM00233): PH domain
RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
Argos (PF11581, IPR021633): Antagonist of EGFR signalling, Argos
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
56 GTF2F1interactorTFIIF_alpha (PF05793, IPR008851): Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
57 HIF1AsuppressorDicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein
HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
PAS (PF00989, IPR013767, SM00091): PAS fold
PAS_3 (PF08447, IPR013655): PAS fold
HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
DQ898313, DQ912588
58 HIPK2suppressorKdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
AF533988, AM600680, AY789120, DQ898313, DQ898314, DQ912588, DQ912589, DQ912590, EU216059, EU216066, FN820225, FN820246
59 HNRNPMinteractorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M
Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
60 HOXA9oncoproteinHox9_act (PF04617, IPR006711): Hox9 activation region
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
AM491359, AM600680, AY789120, DQ898313, DQ912588, EU216059, EU216064, EU216070, EU447303
61 HSPD1suppressorCpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin familyAF533988
62 HSPE1interactorCpn10 (PF00166, IPR020818, SM00883): Chaperonin 10 Kd subunitAF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
63 HUWE1oncoproteinBUD22 (PF09073, IPR015158): BUD22
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation
HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Nop14 (PF04147, IPR007276): Nop14-like family
PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
WWE (PF02825, IPR004170, SM00678): WWE domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
64 IL3oncoproteinIL3 (PF02059, IPR002183): Interleukin-3AM491359, AM600680, AY789120, DQ898313, DQ912588, EU216059, EU216064, EU216070, EU447303
65 ILF3oncoproteindsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
DZF (PF07528, IPR006561, SM00572): DZF domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
66 INPPL1oncoproteinExo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SH2 (PF00017, IPR000980, SM00252): SH2 domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
67 JAK1oncoproteinFERM_M (PF00373, IPR019748): FERM central domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
68 JUNoncoproteinbZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
69 LARSinteractorAnticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA
tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V)
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
70 LATS2suppressorPkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
AF533988
71 LNX1interactorPDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
DQ898313, DQ912588
72 LRRC59interactorHid1 (PF12722): High-temperature-induced dauer-formation protein
LRR_8 (PF13855, IPR001611): Leucine rich repeat
DUF4366 (PF14283, IPR025376): Domain of unknown function (DUF4366)
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
73 MAPTinteractorTubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeatAF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
74 MAVSinteractorIce_nucleation (PF00818, IPR000258): Ice nucleation protein repeat
CARD_2 (PF16739, IPR031964): Caspase recruitment domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
75 MBPinteractorMyelin_MBP (PF01669, IPR000548): Myelin basic proteinAF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
76 MDM2oncoproteinPinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region
Presenilin (PF01080, IPR001108): Presenilin
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
77 MDM4oncoproteinzf-FLZ (PF04570, IPR007650): zinc-finger of the FCS-type, C2-C2
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
78 MICAL1interactorCH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DAO (PF01266, IPR006076): FAD dependent oxidoreductase
FAD_binding_3 (PF01494, IPR002938): FAD binding domain
LIM (PF00412, IPR001781, SM00132): LIM domain
DUF3585 (PF12130, IPR022735): Protein of unknown function (DUF3585)
NAD_binding_7 (PF13241, IPR006367): Putative NAD(P)-binding
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
79 MSH5interactorMutS_V (PF00488, IPR000432, SM00534): MutS domain V
MutS_III (PF05192, IPR007696, SM00533): MutS domain III
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
80 MTORoncoproteinDUF1104 (PF06518, IPR009488): Protein of unknown function (DUF1104)
EPSP_synthase (PF00275, IPR001986): EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
HEAT (PF02985, IPR000357): HEAT repeat
FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain
V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
TPR_19 (PF14559): Tetratricopeptide repeat
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
81 MUC1oncoproteinSEA (PF01390, IPR000082, SM00200): SEA domain
Shisa (PF13908, IPR026910): Wnt and FGF inhibitory regulator
Collectrin (PF16959, IPR031588): Renal amino acid transporter
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
82 MYConcoproteinHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
DQ898313, DQ912588
83 NAA25interactorBTAD (PF03704, IPR005158, SM01043): Bacterial transcriptional activator domain
NatB_MDM20 (PF09797, IPR019183): N-acetyltransferase B complex (NatB) non catalytic subunit
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
Alkyl_sulf_dimr (PF14863, IPR029228): Alkyl sulfatase dimerisation
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
84 NARSinteractortRNA-synt_2 (PF00152, IPR004364): tRNA synthetases class II (D, K and N)
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
85 NCK1oncoproteinSH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
86 NCOA3oncoproteinDUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518)
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator
PAS (PF00989, IPR013767, SM00091): PAS fold
PAS_3 (PF08447, IPR013655): PAS fold
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
SRC-1 (PF08832, IPR014935): Steroid receptor coactivator
PAS_11 (PF14598): PAS domain
DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927)
NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein
AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
87 NEDD4suppressorRota_NS26 (PF01525, IPR002512): Rotavirus NS26
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
88 NEDD4LsuppressorWW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
89 NEDD9interactorSerine_rich (PF08824, IPR014928): Serine rich protein interaction domain
DUF3513 (PF12026, IPR021901): Domain of unknown function (DUF3513)
SH3_9 (PF14604, IPR001452): Variant SH3 domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
90 NFKBIAoncoproteinAnk (PF00023, IPR002110, SM00248): Ankyrin repeat
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
AF533988
91 NINLinteractorPD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat
TBCA (PF02970, IPR004226): Tubulin binding cofactor A
DUF2389 (PF09493, IPR012663): Tryptophan-rich protein (DUF2389)
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
FAM184 (PF15665): Family with sequence similarity 184, A and B
TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
AM600680, DQ898313, DQ912588
92 PAG1interactorPAG (PF15347, IPR032748): Phosphoprotein associated with glycosphingolipid-enrichedAF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
93 PAK2interactorPBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
94 PAK4interactorPBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
95 PARK2suppressorIBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
96 PARP1suppressorBRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain
PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain
PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain
WGR (PF05406, IPR008893, SM00773): WGR domain
zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
97 PCNAoncoproteinPCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain
PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
98 PDE4DoncoproteinNa_trans_assoc (PF06512, IPR010526): Sodium ion transport-associated
PDEase_I (PF00233, IPR002073): 3'5'-cyclic nucleotide phosphodiesterase
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
99 PFDN4interactorPrefoldin_2 (PF01920, IPR002777): Prefoldin subunitAF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
100 PIK3R1oncoproteinRhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
101 PLCG1oncoproteinC2 (PF00168, IPR000008, SM00239): C2 domain
PH (PF00169, IPR001849, SM00233): PH domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
PI-PLC-X (PF00388, IPR000909, SM00148): Phosphatidylinositol-specific phospholipase C, X domain
PI-PLC-Y (PF00387, IPR001711, SM00149): Phosphatidylinositol-specific phospholipase C, Y domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
PH_12 (PF16457, IPR001849): Pleckstrin homology domain
AF533988
102 PPM1BinteractorPP2C (PF00481, IPR001932): Protein phosphatase 2C
PP2C_C (PF07830, IPR012911, SM00332): Protein serine/threonine phosphatase 2C, C-terminal domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
103 PRDX1oncoproteinAhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
104 PRKCZinteractorPB1 (PF00564, IPR000270, SM00666): PB1 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
AF533988
105 PRKDCinteractorFAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
NUC194 (PF08163, IPR012582): NUC194 domain
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
106 PSMA4interactorProteasome (PF00227, IPR001353): Proteasome subunit
U79_P34 (PF03064, IPR004138): HSV U79 / HCMV P34
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
107 PSMA7interactorProteasome (PF00227, IPR001353): Proteasome subunit
Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
108 PSMD4interactorUIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
109 PSTPIP1interactorABATE (PF07336, IPR010852): Putative stress-induced transcription regulator
FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain
WXG100 (PF06013, IPR010310): Proteins of 100 residues with WXG
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
110 PXNoncoproteinLIM (PF00412, IPR001781, SM00132): LIM domain
Paxillin (PF03535): Paxillin family
DQ898313, DQ912588
111 RAC1oncoproteinRas (PF00071, IPR001806, SM00173): Ras familyAF533988
112 RAD51interactorRad51 (PF08423, IPR013632): Rad51
HHH_5 (PF14520): Helix-hairpin-helix domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
113 RAD9AoncoproteinRad9 (PF04139, IPR007268): Rad9AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
114 RANoncoproteinRas (PF00071, IPR001806, SM00173): Ras familyAF533988
115 RAPGEF1oncoproteinRasGEF (PF00617, IPR001895, SM00147): RasGEF domain
RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
116 RASA1oncoproteinC2 (PF00168, IPR000008, SM00239): C2 domain
PH (PF00169, IPR001849, SM00233): PH domain
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
117 REPS1interactorMito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
MCLC (PF05934, IPR009231): Mid-1-related chloride channel (MCLC)
DUF3123 (PF11321, IPR021470): Protein of unknown function (DUF3123)
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
118 RFX1interactorPex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
RFX1_trans_act (PF04589, IPR007668): RFX1 transcription activation region
RFX_DNA_binding (PF02257, IPR003150): RFX DNA-binding domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
119 RHOAsuppressorRas (PF00071, IPR001806, SM00173): Ras familyAF533988
120 RPL37interactorRibosomal_L37e (PF01907, IPR001569): Ribosomal protein L37eAF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
121 RPLP1interactorRibosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal proteinAF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
122 RPS21interactorRibosomal_S21e (PF01249, IPR001931): Ribosomal protein S21eAF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
123 RSPH9interactorRadial_spoke (PF04712, IPR006802): Radial spokehead-like proteinAF113911, AF533988, AM491359, AM491361, AM600680, AY789120, DQ898313, DQ912588, EU216059, EU216064, EU216070, EU447303, M19730, S72479, X06418, X07537
124 RTFDC1interactorRtf2 (PF04641, IPR027799): Rtf2 RING-fingerAF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
125 RYBPinteractorDUF11 (PF01345, IPR001434): Domain of unknown function DUF11
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase (PF00069, IPR000719): Protein kinase domain
PPAK (PF02818, IPR004168): PPAK motif
Titin_Z (PF09042, IPR015129): Titin Z
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Y_Y_Y (PF07495, IPR011123): Y_Y_Y domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
Ig_3 (PF13927): Immunoglobulin domain
AF533988
126 SEC13interactorWD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein
AM600680, DQ898313, DQ912588
127 SFNsuppressor14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 proteinAF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
128 SH3BP1interactorBAR (PF03114, IPR004148, SM00721): BAR domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
129 SH3KBP1interactorTmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein
SH3_9 (PF14604, IPR001452): Variant SH3 domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
130 SHBinteractorHerpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
SH2 (PF00017, IPR000980, SM00252): SH2 domain
Period_C (PF12114, IPR022728): Period protein 2/3C-terminal region
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
131 SHDinteractorSH2 (PF00017, IPR000980, SM00252): SH2 domainAF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
132 SHEinteractorSH2 (PF00017, IPR000980, SM00252): SH2 domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
133 SLC9A2oncoproteinNa_H_Exchanger (PF00999, IPR006153): Sodium/hydrogen exchanger family
Sigma_reg_N (PF13800, IPR029101): Sigma factor regulator N-terminal
NEXCaM_BD (PF16644, IPR032103): Regulatory region of Na+/H+ exchanger NHE binds to calmodulin
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
134 SOCS1suppressorSH2 (PF00017, IPR000980, SM00252): SH2 domain
SOCS_box (PF07525, IPR001496): SOCS box
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
135 SOCS3suppressorSH2 (PF00017, IPR000980, SM00252): SH2 domain
SOCS_box (PF07525, IPR001496): SOCS box
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
136 SORBS1interactorSH3_2 (PF07653, IPR011511): Variant SH3 domain
Sorb (PF02208, IPR003127, SM00459): Sorbin homologous domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
SCAB-ABD (PF16711, IPR032012): Actin-binding domain of plant-specific actin-binding protein
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
137 SORBS2oncoproteinSorb (PF02208, IPR003127, SM00459): Sorbin homologous domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
138 SPAG9interactorDUF501 (PF04417, IPR007511): Protein of unknown function (DUF501)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
IncA (PF04156, IPR007285): IncA protein
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
UPF0449 (PF15136, IPR028227): Uncharacterised protein family UPF0449
JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
139 SPRR2AinteractorSPRR2 (PF14820, IPR029142): Small proline-rich 2AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
140 SPTA1interactorEFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
141 SPTAN1oncoproteinEFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
Tetrabrachion (PF11401, IPR021535): Tetrabrachion
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
142 SRConcoproteinPkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
143 SRPK2oncoproteinDUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Pkinase (PF00069, IPR000719): Protein kinase domain
S-antigen (PF05756, IPR008825): S-antigen protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
144 ST5suppressordDENN (PF03455, IPR005112, SM00801): dDENN domain
DENN (PF02141, IPR001194, SM00799): DENN (AEX-3) domain
DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
uDENN (PF03456, IPR005113, SM00800): uDENN domain
SEEEED (PF14797, IPR029394): Serine-rich region of AP3B1, clathrin-adaptor complex
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
145 STK4oncoproteinPkinase (PF00069, IPR000719): Protein kinase domain
Mst1_SARAH (PF11629, IPR024205): C terminal SARAH domain of Mst1
DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611)
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
146 STON2interactorAdap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family
Stonin2_N (PF12016, IPR022699): Stonin 2
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
147 SUB1interactorDehydrin (PF00257, IPR000167): Dehydrin
PC4 (PF02229, IPR003173): Transcriptional Coactivator p15 (PC4)
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
148 TERF1interactorTRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
AF533988, AM600680, AY789120, DQ898313, DQ898314, DQ912588, DQ912589, DQ912590, EU216059, EU216066, FN820225, FN820246
149 TOPBP1interactorBRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
PTCB-BRCT (PF12738, IPR001357): twin BRCT domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
150 TP73suppressorP53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
AF533988
151 TSG101suppressorAPG6 (PF04111, IPR007243): Autophagy protein Apg6
Laminin_II (PF06009, IPR010307): Laminin Domain II
UEV (PF05743, IPR008883): UEV domain
Vps23_core (PF09454, IPR017916): Vps23 core domain
AM491359, AM600680, AY789120, DQ898313, DQ912588, EU216059, EU216064, EU216070, EU447303
152 TUBinteractorTub (PF01167, IPR000007): Tub family
Tub_N (PF16322, IPR005398): Tubby N-terminal
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
153 UNC119interactorGMP_PDE_delta (PF05351, IPR008015): GMP-PDE, delta subunitAF533988, AM491359, AM600680, AY789120, DQ898313, DQ912588, EU216059, EU216064, EU216070, EU447303
154 USP7oncoproteinMATH (PF00917, IPR002083, SM00061): MATH domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7
USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
155 VAV1oncoproteinPH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
156 VPS28interactorVPS28 (PF03997, IPR007143): VPS28 proteinAM491359, AM600680, AY789120, DQ898313, DQ912588, EU216059, EU216064, EU216070, EU447303
157 WASF1interactorMito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
WH2 (PF02205, IPR003124, SM00246): WH2 motif
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
158 WDR48suppressorWD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF3337 (PF11816, IPR021772): Domain of unknown function (DUF3337)
AM491359, AM600680, AY789120, DQ898313, DQ912588, EU216059, EU216064, EU216070, EU447303
159 WRNIP1interactorAAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
RuvB_N (PF05496, IPR008824): Holliday junction DNA helicase ruvB N-terminus
Sgf11 (PF08209, IPR013246): Sgf11 (transcriptional regulation protein)
MgsA_C (PF12002, IPR021886): MgsA AAA+ ATPase C terminal
AAA_assoc_2 (PF16193, IPR032423): AAA C-terminal domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
160 XPO1interactorCRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
AF533988
161 XRCC6oncoproteinKu (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
SAP (PF02037, IPR003034, SM00513): SAP domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
162 YAP1suppressorBindin (PF02084, IPR000775): Bindin
WW (PF00397, IPR001202, SM00456): WW domain
GspL_C (PF12693, IPR025691): GspL periplasmic domain
FAM181 (PF15238, IPR029359): FAM181
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
163 YTHDC1interactorDUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
YTH (PF04146, IPR007275): YT521-B-like domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
TFB6 (PF17110, IPR031349): Subunit 11 of the general transcription factor TFIIH
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
164 YWHABinteractor14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
Virulence_fact (PF13769, IPR025989): Virulence factor
AF533988
165 YWHAEoncoprotein14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 proteinAF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
166 YWHAGinteractor14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 proteinAF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
167 YWHAHinteractor14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 proteinAF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
168 YWHAQinteractor14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 proteinAF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
169 YWHAZinteractor14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 proteinAF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
170 ZAP70interactorPkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246
171 ZDHHC16interactorDUF1049 (PF06305, IPR010445): Protein of unknown function (DUF1049)
NS3_envE (PF02723, IPR003873): Non-structural protein NS3/Small envelope protein E
zf-DHHC (PF01529, IPR001594): DHHC palmitoyltransferase
AF533988, DQ898314, DQ912589, DQ912590, FN820225, FN820246

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