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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)115
The number (and %) of the onco-proteins22 (19.13 %)
The number (and %) of the tumor suppressors8 (6.96 %)
Total number of binary PPIs (saturation %)911 (13.90 %)
The number (and %) of affected PPIs115 (12.62 %)
The number of possible different fusions17
PPI diameter4
PPI radius2
The average degree of PPI15.322
Assortativity coefficient-0.0711
The network average Clustering coefficient0.490
The number (and %) of a zero Clustering coefficients3 (2.61 %)
The number (and %) of a zero Betweenness Centrality9 (7.83 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: NDUFA9,TELO2 All fusions
Proteins found in more fusions MME (see 1 fusions); HLA-B (see 2 fusions); MAGED1 (see 1 fusions); VCP (see 4 fusions); ATR (see 1 fusions); ATP6V1C1 (see 3 fusions); GMDS (see 2 fusions); DSP (see 4 fusions); NDUFS3 (see 1 fusions); PRKDC (see 3 fusions); IMMT (see 4 fusions); EGFR (see 2 fusions); APC (see 1 fusions); TSC22D1 (see 5 fusions); MTOR (see 1 fusions); COPG1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 NDUFA9parental protein770.2013315.213Epimerase (PF01370, IPR001509): NAD dependent epimerase/dehydratase family
2 TELO2parental protein380.1581267.426Telomere_reg-2 (PF10193, IPR019337): Telomere length regulation protein
HEAT_2 (PF13646): HEAT repeats
3 ABCC2interactor70.3334.926ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
DUF805 (PF05656, IPR008523): Protein of unknown function (DUF805)
DUF87 (PF01935, IPR002789): Domain of unknown function DUF87
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
4 AFG3L2interactor180.386148.167AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
FtsH_ext (PF06480, IPR011546): FtsH Extracellular
Peptidase_M41 (PF01434, IPR000642): Peptidase family M41
TniB (PF05621, IPR008868): Bacterial TniB protein
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
5 AK2interactor50.50016.444ADK (PF00406, IPR000850): Adenylate kinase
AAA_33 (PF13671): AAA domain
6 APCsuppressor40.6677.324APC_15aa (PF05972, IPR009240): APC 15 residue motif
APC_basic (PF05956, IPR009234): APC basic domain
APC_r (PF05923): APC repeat
Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
EB1_binding (PF05937, IPR009232): EB-1 Binding Domain
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
SAMP (PF05924, IPR009224): SAMP Motif
Suppressor_APC (PF11414, IPR026831): Adenomatous polyposis coli tumour suppressor protein
AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term
SAS4 (PF15460, IPR029184): Something about silencing, SAS, complex subunit 4
Arm_APC_u3 (PF16629): Armadillo-associated region on APC
APC_u5 (PF16630): Unstructured region on APC between 1st and 2nd catenin-bdg motifs
APC_u9 (PF16633): Unstructured region on APC between 1st two creatine-rich regions
APC_u13 (PF16634): Unstructured region on APC between APC_crr and SAMP
APC_u14 (PF16635): Unstructured region on APC between SAMP and APC_crr
APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6
APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
7 ATMsuppressor90.39383.326FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
HEAT (PF02985, IPR000357): HEAT repeat
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair
ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
8 ATP1B3interactor140.47375.343Na_K-ATPase (PF00287, IPR000402): Sodium / potassium ATPase beta chain
9 ATP5F1interactor210.44390.460Mt_ATP-synt_B (PF05405, IPR008688): Mitochondrial ATP synthase B chain precursor (ATP-synt_B)
DUF2105 (PF09878, IPR019212): Predicted membrane protein (DUF2105)
10 ATP6V1C1protein found in more fusions31.0000V-ATPase_C (PF03223, IPR004907): V-ATPase subunit C
11 ATRsuppressor100.41737.715FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
HEAT (PF02985, IPR000357): HEAT repeat
Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1
THP2 (PF09432, IPR018557): Tho complex subunit THP2
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
UME (PF08064, IPR012993, SM00802): UME (NUC010) domain
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
HEAT_EZ (PF13513): HEAT-like repeat
SgrT (PF15894, IPR031767): Inhibitor of glucose uptake transporter SgrT
12 BSGinteractor80.35715.100Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
13 C15orf48interactor300.42886.751B12D (PF06522, IPR010530): NADH-ubiquinone reductase complex 1 MLRQ subunit
14 CACNA1Ainteractor50.10050.114Ca_chan_IQ (PF08763, IPR014873, SM01062): Voltage gated calcium channel IQ domain
GRP (PF07172, IPR010800): Glycine rich protein family
Ion_trans (PF00520, IPR005821): Ion transport protein
Roughex (PF06020, IPR009259): Drosophila roughex protein
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
GPHH (PF16905, IPR031649): Voltage-dependent L-type calcium channel, IQ-associated
15 CLN3interactor90.22277.844CLN3 (PF02487, IPR003492): CLN3 protein
16 CLTConcoprotein150.333209.986Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker
Clathrin_propel (PF01394, IPR022365): Clathrin propeller repeat
Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS
Clathrin_H_link (PF13838): Clathrin-H-link
17 COPB2interactor100.47228.498Coatomer_WDAD (PF04053, IPR006692): Coatomer WD associated region
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
18 COPG1protein found in more fusions110.48928.254Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
COP-gamma_platf (PF08752, IPR013040): Coatomer gamma subunit appendage platform subdomain
Coatomer_g_Cpla (PF16381, IPR032154): Coatomer subunit gamma-1 C-terminal appendage platform
19 CORO1Binteractor40.5004.528DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899)
Trimer_CC (PF08954, IPR015049, SM01167): Trimerisation motif
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
WD40_4 (PF16300): Type of WD40 repeat
20 COX15interactor60.66712.203COX15-CtaA (PF02628, IPR003780): Cytochrome oxidase assembly protein
Peptidase_S3 (PF00944, IPR000930): Alphavirus core protein
21 COX6B1interactor120.5274.747COX6B (PF02297, IPR003213): Cytochrome oxidase c subunit VIb
22 CRKLoncoprotein40.6671.476SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
23 CYTBinteractor30.6671.185NA
24 DLDinteractor90.33346.061Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
Pyr_redox_dim (PF02852, IPR004099): Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
25 DNAJB1suppressor40.5003.056DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
26 DSPsuppressor50.8330.917APG6 (PF04111, IPR007243): Autophagy protein Apg6
ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
BRE1 (PF08647, IPR013956): BRE1 E3 ubiquitin ligase
CLP_protease (PF00574, IPR023562): Clp protease
DUF1192 (PF06698, IPR009579): Protein of unknown function (DUF1192)
DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Fez1 (PF06818): Fez1
FIVAR (PF07554, IPR011490): Uncharacterised Sugar-binding Domain
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
Occludin_ELL (PF07303, IPR010844): Occludin homology domain
Rho_Binding (PF08912, IPR015008): Rho Binding
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Spectrin (PF00435, IPR002017): Spectrin repeat
TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
Plectin (PF00681, IPR001101, SM00250): Plectin repeat
DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570)
SOGA (PF11365, IPR027881): Protein SOGA
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
FAM184 (PF15665): Family with sequence similarity 184, A and B
JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
27 EGFRoncoprotein230.299551.837Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
28 ELAVL1oncoprotein220.190435.842RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
29 EMC8interactor21.0000UPF0172 (PF03665, IPR005366): Uncharacterised protein family (UPF0172)
30 FBXO6interactor220.242303.870FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
31 FN1oncoprotein200.205378.969fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
32 GMDSprotein found in more fusions200GDP_Man_Dehyd (PF16363, IPR016040): GDP-mannose 4,6 dehydratase
33 GOLT1Binteractor320.429134.885Got1 (PF04178, IPR007305): Got1/Sft2-like family
34 GTSE1interactor40.5007.626GTSE1_N (PF15259, IPR032768): G-2 and S-phase expressed 1
35 HLA-Boncoprotein409.757MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2
MHC_I_C (PF06623, IPR010579): MHC_I C-terminus
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
36 HSPA4interactor130.39754.013Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region
HSP70 (PF00012, IPR013126): Hsp70 protein
TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
37 HTR6interactor70.52411.5947tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
38 IMMTprotein found in more fusions200.380149.147Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
39 IQGAP1interactor110.29199.117CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF87 (PF01935, IPR002789): Domain of unknown function DUF87
IDEAL (PF08858, IPR014957, SM00914): IDEAL domain
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
RasGAP_C (PF03836, IPR000593): RasGAP C-terminus
WW (PF00397, IPR001202, SM00456): WW domain
40 KRASoncoprotein60.40038.922Ras (PF00071, IPR001806, SM00173): Ras family
41 KRT15interactor21.0000Filament (PF00038, IPR001664): Intermediate filament protein
Keratin_2_head (PF16208, IPR032444): Keratin type II head
42 MAGED1protein found in more fusions51.0000MAGE (PF01454, IPR002190): MAGE family
43 MASTLinteractor100Pkinase (PF00069, IPR000719): Protein kinase domain
44 MCUinteractor60.4675.010MCU (PF04678, IPR006769): Mitochondrial calcium uniporter
45 MMEsuppressor100.19470.940Peptidase_M13 (PF01431, IPR018497): Peptidase family M13
Peptidase_M13_N (PF05649, IPR008753): Peptidase family M13
46 MRPL58interactor180.42527.188RF-1 (PF00472, IPR000352): RF-1 domain
47 MT-ND5interactor90.9720.148NADH5_C (PF06455, IPR010934): NADH dehydrogenase subunit 5 C-terminus
Proton_antipo_M (PF00361, IPR001750): Proton-conducting membrane transporter
Proton_antipo_N (PF00662, IPR001516): NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
48 MTORoncoprotein110.51113.979DUF1104 (PF06518, IPR009488): Protein of unknown function (DUF1104)
EPSP_synthase (PF00275, IPR001986): EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
HEAT (PF02985, IPR000357): HEAT repeat
FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain
V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
TPR_19 (PF14559): Tetratricopeptide repeat
49 NDUFA10interactor190.43992.790dNK (PF01712, IPR002624): Deoxynucleoside kinase
50 NDUFA11interactor290.46676.9637kD_coat (PF02495, IPR003411): 7kD viral coat protein
Tim17 (PF02466, IPR003397): Tim17/Tim22/Tim23/Pmp24 family
51 NDUFA12interactor410.452141.859NDUFA12 (PF05071, IPR007763): NADH ubiquinone oxidoreductase subunit NDUFA12
52 NDUFA13interactor200.65816.396GRIM-19 (PF06212, IPR009346): GRIM-19 protein
53 NDUFA2interactor220.54150.119L51_S25_CI-B8 (PF05047, IPR007741, SM00916): Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
54 NDUFA4interactor400.375196.079B12D (PF06522, IPR010530): NADH-ubiquinone reductase complex 1 MLRQ subunit
55 NDUFA5interactor160.55826.969ETC_C1_NDUFA5 (PF04716, IPR006806): ETC complex I subunit conserved region
56 NDUFA6interactor130.6285.059Complex1_LYR (PF05347, IPR008011): Complex 1 protein (LYR family)
57 NDUFA7interactor130.6795.405CI-B14_5a (PF07347, IPR009947): NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a)
58 NDUFA8interactor310.473193.921CHCH (PF06747, IPR010625): CHCH domain
Pet191_N (PF10203, IPR018793): Cytochrome c oxidase assembly protein PET191
Cdd1 (PF11731, IPR021725): Pathogenicity locus
59 NDUFAB1interactor31.0000MinE (PF03776, IPR005527): Septum formation topological specificity factor MinE
PP-binding (PF00550, IPR009081): Phosphopantetheine attachment site
60 NDUFB1interactor80.7141.979NADH_oxidored (PF08040, IPR012575): MNLL subunit
61 NDUFB10interactor170.57463.313NDUFB10 (PF10249, IPR019377): NADH-ubiquinone oxidoreductase subunit 10
62 NDUFB11interactor110.7272.760ESSS (PF10183, IPR019329): ESSS subunit of NADH:ubiquinone oxidoreductase (complex I)
63 NDUFB3interactor80.8570.556NDUF_B12 (PF08122, IPR012576): NADH-ubiquinone oxidoreductase B12 subunit family
64 NDUFB4interactor180.66721.535NDUF_B4 (PF07225, IPR009866): NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4)
65 NDUFB5interactor160.65012.733NDUF_B5 (PF09781, IPR019173): NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit
66 NDUFB7interactor160.57513.310DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
NDUF_B7 (PF05676, IPR008698): NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7)
OrfB_IS605 (PF01385, IPR001959): Probable transposase
67 NDUFB8interactor190.53273.232NDUF_B8 (PF05821, IPR008699): NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8)
68 NDUFB9interactor220.47658.848Complex1_LYR (PF05347, IPR008011): Complex 1 protein (LYR family)
69 NDUFS1interactor360.432299.408NADH_dhqG_C (PF09326, IPR015405): NADH-ubiquinone oxidoreductase subunit G, C-terminal
Fer4 (PF00037, IPR001450): 4Fe-4S binding domain
Molybdopterin (PF00384, IPR006656): Molybdopterin oxidoreductase
NADH-G_4Fe-4S_3 (PF10588, IPR019574, SM00929): NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
Fer2_4 (PF13510): 2Fe-2S iron-sulfur cluster binding domain
70 NDUFS2interactor270.553112.312Complex1_49kDa (PF00346, IPR001135): Respiratory-chain NADH dehydrogenase, 49 Kd subunit
NiFeSe_Hases (PF00374, IPR001501): Nickel-dependent hydrogenase
71 NDUFS3protein found in more fusions480.360593.102Complex1_30kDa (PF00329, IPR001268): Respiratory-chain NADH dehydrogenase, 30 Kd subunit
72 NDUFS4interactor330.50282.731ETC_C1_NDUFA4 (PF04800, IPR006885): ETC complex I subunit conserved region
73 NDUFS5interactor330.53061.160Ndufs5 (PF10200, IPR019342): NADH:ubiquinone oxidoreductase, NDUFS5-15kDa
74 NDUFS6interactor240.66331.304Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain
zf-CHCC (PF10276, IPR019401, SM00400): Zinc-finger domain
75 NDUFS7interactor230.70625.938Oxidored_q6 (PF01058, IPR006137): NADH ubiquinone oxidoreductase, 20 Kd subunit
76 NDUFS8interactor280.49778.725Fer4_7 (PF12838, IPR001450): 4Fe-4S dicluster domain
Fer4_16 (PF13484): 4Fe-4S double cluster binding domain
77 NDUFV1interactor330.54064.754Complex1_51K (PF01512, IPR011538): Respiratory-chain NADH dehydrogenase 51 Kd subunit
NADH_4Fe-4S (PF10589, IPR019575, SM00928): NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
SLBB (PF10531, IPR019554): SLBB domain
78 NDUFV2interactor280.60660.0652Fe-2S_thioredx (PF01257, IPR002023): Thioredoxin-like [2Fe-2S] ferredoxin
79 NDUFV3interactor140.8681.697DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
NDUFV3 (PF15880, IPR026193): NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
80 NNTinteractor60.46713.604AlaDh_PNT_C (PF01262, IPR007698, SM01002): Alanine dehydrogenase/PNT, C-terminal domain
AlaDh_PNT_N (PF05222, IPR007886, SM01003): Alanine dehydrogenase/PNT, N-terminal domain
PNTB (PF02233, IPR012136): NAD(P) transhydrogenase beta subunit
PNTB_4TM (PF12769, IPR024605): 4TM region of pyridine nucleotide transhydrogenase, mitoch
81 NTRK1oncoprotein440.1571966.237I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
82 OCIAD1interactor140.47480.668OCIA (PF07051, IPR009764): Ovarian carcinoma immunoreactive antigen (OCIA)
83 OPA1interactor70.52411.696DUF1593 (PF07632, IPR011483): Protein of unknown function (DUF1593)
Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like
IncA (PF04156, IPR007285): IncA protein
Ras (PF00071, IPR001806, SM00173): Ras family
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
DUF4061 (PF13270, IPR025271): Domain of unknown function (DUF4061)
84 PIDD1interactor40.5001.833Death (PF00531, IPR000488, SM00005): Death domain
ZU5 (PF00791, IPR000906, SM00218): ZU5 domain
Peptidase_S68 (PF10461, IPR019502): Peptidase S68
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
85 PIH1D1interactor70.9050.929PIH1 (PF08190, IPR012981): pre-RNA processing PIH1/Nop17
86 PPP4R3Ainteractor21.0000Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
SMK-1 (PF04802, IPR006887): Component of IIS longevity pathway SMK-1
WH1 (PF00568, IPR000697, SM00461): WH1 domain
DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611)
87 PRKDCprotein found in more fusions140.38592.283FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
NUC194 (PF08163, IPR012582): NUC194 domain
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
88 PSMD6interactor30.33322.950RPN7 (PF10602, IPR019585): 26S proteasome subunit RPN7
PCI (PF01399, IPR000717, SM00088): PCI domain
89 RNF2interactor200.216276.402zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
90 RPAP3interactor90.69425.168TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
RPAP3_C (PF13877, IPR025986): Potential Monad-binding region of RPAP3
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
91 RUFY1interactor61.0000DM (PF00751, IPR001275, SM00301): DM DNA binding domain
FAA_hydrolase_N (PF09298, IPR015377): Fumarylacetoacetase N-terminal
DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
RUN (PF02759, IPR004012, SM00593): RUN domain
Tektin (PF03148, IPR000435): Tektin family
92 RUVBL1oncoprotein200.351180.287TIP49 (PF06068, IPR010339): TIP49 C-terminus
93 RUVBL2oncoprotein180.360142.062TIP49 (PF06068, IPR010339): TIP49 C-terminus
94 SDHBsuppressor190.42745.674Fer2_3 (PF13085, IPR025192): 2Fe-2S iron-sulfur cluster binding domain
Fer4_8 (PF13183, IPR017896): 4Fe-4S dicluster domain
Fer4_17 (PF13534): 4Fe-4S dicluster domain
95 SENP3interactor100.289136.764Nop53 (PF07767, IPR011687): Nop53 (60S ribosomal biogenesis)
Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain
96 SMG1interactor80.5718.786Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
FATC (PF02260, IPR003152): FATC domain
HEAT (PF02985, IPR000357): HEAT repeat
FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
XhlA (PF10779, IPR019715): Haemolysin XhlA
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
SMG1 (PF15785, IPR031559): Serine/threonine-protein kinase smg-1
97 SSR1interactor100.37865.190TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
98 TCTN3interactor130.385107.876DUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619)
99 TIMMDC1interactor220.48955.651Tim17 (PF02466, IPR003397): Tim17/Tim22/Tim23/Pmp24 family
100 TPM4oncoprotein60.33347.273Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
101 TRRAPinteractor60.7332.850BALF1 (PF06861, IPR010677): BALF1 protein
BP28CT (PF08146, IPR012954, SM01036): BP28CT (NUC211) domain
DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
CLASP_N (PF12348, IPR024395): CLASP N terminal
Sec7_N (PF12783, IPR032691): Guanine nucleotide exchange factor in Golgi transport N-terminal
HEAT_EZ (PF13513): HEAT-like repeat
TRC8_N (PF13705, IPR025754): TRC8 N-terminal domain
ACDC (PF14733, IPR028078): AP2-coincident C-terminal
102 TSC22D1suppressor50.16728.445SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
103 TTI1interactor210.338171.868Dopey_N (PF04118, IPR007249): Dopey, N-terminal
HEAT (PF02985, IPR000357): HEAT repeat
VHS (PF00790, IPR002014, SM00288): VHS domain
CLASP_N (PF12348, IPR024395): CLASP N terminal
104 TTI2interactor120.48533.231Tti2 (PF10521, IPR018870): Tti2 family
105 UQCR10interactor60.6004.492UCR_UQCRX_QCR9 (PF05365, IPR008027): Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like
106 UQCRC2oncoprotein260.372216.417Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
107 UQCRFS1interactor180.50333.198Rieske (PF00355, IPR017941): Rieske [2Fe-2S] domain
Ubiq-Cytc-red_N (PF09165, IPR015248): Ubiquinol-cytochrome c reductase 8 kDa, N-terminal
UCR_TM (PF02921, IPR004192): Ubiquinol cytochrome reductase transmembrane region
108 VAPAinteractor340.365375.139DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
UL45 (PF05473, IPR008646): UL45 protein, carbohydrate-binding C-type lectin-like
Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain
109 VCPprotein found in more fusions160.276131.705AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
110 VDAC1interactor150.55236.460Porin_3 (PF01459, IPR027246): Eukaryotic porin
111 VDAC2interactor210.410115.205Porin_3 (PF01459, IPR027246): Eukaryotic porin
112 VDAC3interactor190.36887.434Porin_3 (PF01459, IPR027246): Eukaryotic porin
113 XPO1interactor190.257344.775CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
114 YBX1oncoprotein70.47616.028CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
115 YBX3interactor50.40028.489CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain
Herpes_LMP1 (PF05297, IPR007961): Herpesvirus latent membrane protein 1 (LMP1)

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