Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins PRKCI, CD63 (from a repository: Mon Aug 19 16:42:10 2019)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 91 The number (and %) of the onco-proteins 25 (27.47 %) The number (and %) of the tumor suppressors 11 (12.09 %) Total number of binary PPIs (saturation %) 378 (9.23 %) The number (and %) of affected PPIs 89 (23.54 %) The number of possible different fusions 16 PPI diameter 5 PPI radius 3 The average degree of PPI 7.648 Assortativity coefficient -0.2185 The network average Clustering coefficient 0.489 The number (and %) of a zero Clustering coefficients 11 (12.09 %) The number (and %) of a zero Betweenness Centrality 25 (27.47 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: PRKCI,CD63	All fusions
Proteins found in more fusions	LGALS3 (see 2 fusions); APP (see 5 fusions); HSP90AA1 (see 6 fusions); SFPQ (see 6 fusions); YWHAZ (see 5 fusions); NPM1 (see 1 fusions); TSC22D1 (see 4 fusions); IKBKB (see 2 fusions); SQSTM1 (see 5 fusions); MARK2 (see 2 fusions); CDC37 (see 2 fusions); VHL (see 1 fusions); YWHAH (see 2 fusions); GAPDH (see 5 fusions); YWHAZ/PARD3 (see 1 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	PRKCI	parental protein	69	0.090	4365.391	PB1 (PF00564, IPR000270, SM00666): PB1 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
2	CD63	parental protein	20	0.158	782.944	Tetraspannin (PF00335, IPR018499): Tetraspanin family DUF4282 (PF14110, IPR025557): Domain of unknown function (DUF4282)
3	ADAP1	interactor	2	1.000	0	ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf PH (PF00169, IPR001849, SM00233): PH domain
4	AMOT	oncoprotein	8	0.524	8.525	FAP (PF07174, IPR010801): Fibronectin-attachment protein (FAP) Gastrin (PF00918, IPR001651, SM00029): Gastrin/cholecystokinin family DUF2162 (PF09930, IPR017199): Predicted transporter (DUF2162) Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
5	APP	protein found in more fusions	20	0.216	426.862	APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
6	ARHGAP17	interactor	5	0.800	1.058	BAR (PF03114, IPR004148, SM00721): BAR domain RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
7	ATP6V1B1	interactor	3	0.333	36.084	ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain DUF3533 (PF12051, IPR022703): Protein of unknown function (DUF3533)
8	BAD	oncoprotein	4	1.000	0	Bcl-2_BAD (PF10514, IPR018868): Pro-apoptotic Bcl-2 protein, BAD
9	CASP8	suppressor	7	0.600	6.626	DED (PF01335, IPR001875, SM00031): Death effector domain Peptidase_C14 (PF00656, IPR011600): Caspase domain
10	CD81	interactor	11	0.289	344.426	Tetraspannin (PF00335, IPR018499): Tetraspanin family
11	CD82	suppressor	7	0.476	52.504	Tetraspannin (PF00335, IPR018499): Tetraspanin family
12	CD9	oncoprotein	9	0.389	176.197	Tetraspannin (PF00335, IPR018499): Tetraspanin family
13	CDC37	protein found in more fusions	12	0.455	26.194	CDC37_C (PF08564, IPR013873, SM01069): Cdc37 C terminal domain CDC37_M (PF08565, IPR013874, SM01070): Cdc37 Hsp90 binding domain CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding Rho_Binding (PF08912, IPR015008): Rho Binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
14	CDK7	oncoprotein	6	0.700	2.833	Pkinase (PF00069, IPR000719): Protein kinase domain
15	CEP135	interactor	5	0.300	130.054	DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724) ERM (PF00769, IPR011259): Ezrin/radixin/moesin family LPP (PF04728, IPR006817): Lipoprotein leucine-zipper RasGAP_C (PF03836, IPR000593): RasGAP C-terminus Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein TPD52 (PF04201, IPR007327): Tumour protein D52 family CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein KASH_CCD (PF14662, IPR028168): Coiled-coil region of CCDC155 or KASH HMMR_N (PF15905, IPR031787): Hyaluronan mediated motility receptor N-terminal GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase
16	CHUK	suppressor	11	0.489	40.697	Pkinase (PF00069, IPR000719): Protein kinase domain IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
17	CRX	interactor	1	0	0	TF_Otx (PF03529, IPR013851): Otx1 transcription factor Homeobox (PF00046, IPR001356, SM00389): Homeobox domain SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
18	DUSP1	suppressor	3	1.000	0	DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain
19	EIF4ENIF1	interactor	2	1.000	0	EIF4E-T (PF10477, IPR018862): Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF4718 (PF15842, IPR031695): Domain of unknown function (DUF4718)
20	ELAVL1	oncoprotein	16	0.133	689.875	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
21	FABP4	interactor	1	0	0	Lipocalin (PF00061, IPR000566): Lipocalin / cytosolic fatty-acid binding protein family
22	FAM134C	interactor	4	0.167	87.943	Reticulon (PF02453, IPR003388): Reticulon
23	FRS2	interactor	2	1.000	0	IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
24	GAB1	oncoprotein	3	1.000	0	PH (PF00169, IPR001849, SM00233): PH domain
25	GABARAPL1	interactor	9	0.583	54.768	Atg8 (PF02991, IPR004241): Autophagy protein Atg8 ubiquitin like VitD-bind_III (PF09164, IPR015247): Vitamin D binding protein, domain III
26	GABARAPL2	interactor	9	0.528	20.139	Atg8 (PF02991, IPR004241): Autophagy protein Atg8 ubiquitin like
27	GAPDH	oncoprotein	7	0.600	93.974	Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain OstA (PF03968, IPR005653): OstA-like protein
28	GBAS	interactor	10	0.600	12.108	NIPSNAP (PF07978, IPR012577): NIPSNAP
29	HLA-DMB	interactor	3	1.000	0	MHC_II_beta (PF00969, IPR000353, SM00921): Class II histocompatibility antigen, beta domain C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
30	HLA-DOB	interactor	2	1.000	0	MHC_II_beta (PF00969, IPR000353, SM00921): Class II histocompatibility antigen, beta domain C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
31	HLA-DRA	interactor	6	0.200	366.950	MHC_II_alpha (PF00993, IPR001003, SM00920): Class II histocompatibility antigen, alpha domain C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain C1-set_C (PF16196, IPR032431): C1-set C-terminal domain
32	HSP90AA1	oncoprotein	18	0.265	250.520	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
33	IKBKB	protein found in more fusions	9	0.607	8.397	FliT (PF05400, IPR008622): Flagellar protein FliT Glyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain Pkinase (PF00069, IPR000719): Protein kinase domain SlyX (PF04102, IPR007236): SlyX ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
34	IKBKG	interactor	9	0.571	9.500	CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725) NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
35	IL1RAP	interactor	1	0	0	ig (PF00047, IPR013151, SM00409): Immunoglobulin domain TIR (PF01582, IPR000157, SM00255): TIR domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain
36	ITGB1	suppressor	8	0.286	217.912	EGF_2 (PF07974, IPR013111): EGF-like domain Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain Integrin_beta (PF00362, IPR002369, SM00187): Integrin beta chain VWA domain PSI_integrin (PF17205): Integrin plexin domain
37	KIF23	interactor	5	0.700	2.167	DUF730 (PF05325, IPR007989): Protein of unknown function (DUF730) Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding MKLP1_Arf_bdg (PF16540, IPR032384): Arf6-interacting domain of mitotic kinesin-like protein 1
38	KIT	oncoprotein	3	1.000	0	ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain
39	LGALS3	oncoprotein	8	0.333	325.475	Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
40	LGALS8	interactor	5	0.400	19.895	Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
41	LGALS9	interactor	5	0.600	27.827	Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin Peptidase_C62 (PF12380, IPR024348): Gill-associated viral 3C-like peptidase
42	LLGL1	suppressor	11	0.473	32.039	Lgl_C (PF08596, IPR013905): Lethal giant larvae(Lgl) like, C-terminal LLGL (PF08366, IPR013577): LLGL2 WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
43	LLGL2	interactor	7	0.733	1.994	Lgl_C (PF08596, IPR013905): Lethal giant larvae(Lgl) like, C-terminal LLGL (PF08366, IPR013577): LLGL2 WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N (PF14655, IPR032839): Rab3 GTPase-activating protein regulatory subunit N-terminus
44	MAGED2	interactor	3	1.000	0	CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27 MAGE (PF01454, IPR002190): MAGE family SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
45	MAP1LC3A	interactor	10	0.467	135.188	Atg8 (PF02991, IPR004241): Autophagy protein Atg8 ubiquitin like
46	MAP1LC3B	interactor	7	0.810	1.952	Atg8 (PF02991, IPR004241): Autophagy protein Atg8 ubiquitin like
47	MAP2K5	oncoprotein	7	0.733	1.618	PB1 (PF00564, IPR000270, SM00666): PB1 domain Pkinase (PF00069, IPR000719): Protein kinase domain
48	MARK2	protein found in more fusions	12	0.509	25.356	DUF702 (PF05142, IPR007818): Domain of unknown function (DUF702) KA1 (PF02149, IPR001772): Kinase associated domain 1 Pkinase (PF00069, IPR000719): Protein kinase domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
49	MARK4	oncoprotein	6	0.600	6.243	KA1 (PF02149, IPR001772): Kinase associated domain 1 Pkinase (PF00069, IPR000719): Protein kinase domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
50	MASTL	interactor	1	0	0	Pkinase (PF00069, IPR000719): Protein kinase domain
51	MBP	interactor	5	0.400	70.381	Myelin_MBP (PF01669, IPR000548): Myelin basic protein
52	MYO10	interactor	3	0.667	0.500	DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682) FERM_M (PF00373, IPR019748): FERM central domain IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif MyTH4 (PF00784, IPR000857, SM00139): MyTH4 domain Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region PH (PF00169, IPR001849, SM00233): PH domain RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) VIR_N (PF15912, IPR031801): Virilizer, N-terminal MYO10_CC (PF16735, IPR031971): Unconventional myosin-X coiled coil domain
53	NIPSNAP1	interactor	10	0.622	12.473	NIPSNAP (PF07978, IPR012577): NIPSNAP
54	NPM1	suppressor	15	0.418	233.953	Nucleoplasmin (PF03066): Nucleoplasmin/nucleophosmin domain SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
55	PARD3	protein found in more fusions	18	0.366	81.762	PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DUF3534 (PF12053, IPR021922): Domain of unknown function (DUF3534) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
56	PARD6A	interactor	16	0.400	47.582	PB1 (PF00564, IPR000270, SM00666): PB1 domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
57	PARD6B	interactor	13	0.462	45.077	PB1 (PF00564, IPR000270, SM00666): PB1 domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
58	PARD6G	interactor	9	0.667	6.602	PB1 (PF00564, IPR000270, SM00666): PB1 domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
59	PDPK1	interactor	6	0.600	2.271	Pkinase (PF00069, IPR000719): Protein kinase domain PH_3 (PF14593): PH domain
60	PNMA1	oncoprotein	5	0.400	130.686	PNMA (PF14893, IPR026523): PNMA
61	PPM1A	suppressor	2	1.000	0	PP2C (PF00481, IPR001932): Protein phosphatase 2C PP2C_C (PF07830, IPR012911, SM00332): Protein serine/threonine phosphatase 2C, C-terminal domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
62	PPM1B	interactor	8	0.429	13.224	PP2C (PF00481, IPR001932): Protein phosphatase 2C PP2C_C (PF07830, IPR012911, SM00332): Protein serine/threonine phosphatase 2C, C-terminal domain
63	PRKCZ	interactor	18	0.382	70.897	PB1 (PF00564, IPR000270, SM00666): PB1 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
64	PTGFRN	interactor	7	0.476	19.600	V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain
65	RAB4A	oncoprotein	1	0	0	Ras (PF00071, IPR001806, SM00173): Ras family
66	RAPGEF2	interactor	3	1.000	0	PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain RasGEF (PF00617, IPR001895, SM00147): RasGEF domain RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain
67	RASSF8	suppressor	8	0.679	6.416	ETC_C1_NDUFA5 (PF04716, IPR006806): ETC complex I subunit conserved region FliD_C (PF07195, IPR010809): Flagellar hook-associated protein 2 C-terminus PEARLI-4 (PF05278, IPR007942): Arabidopsis phospholipase-like protein (PEARLI 4) RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
68	RHOJ	interactor	2	1.000	0	Ras (PF00071, IPR001806, SM00173): Ras family
69	RNF13	interactor	4	0.500	2.167	DNA_ligase_ZBD (PF03119, IPR004149): NAD-dependent DNA ligase C4 zinc finger domain PA (PF02225, IPR003137): PA domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain FAM176 (PF14851): FAM176 family STAC2_u1 (PF16664): Unstructured on SH3 and cysteine-rich domain-containing protein 2
70	SDC1	oncoprotein	3	0.333	58.557	Herpes_TAF50 (PF03326, IPR004998): Herpesvirus transcription activation factor (transactivator) Syndecan (PF01034, IPR027789): Syndecan domain DUF3592 (PF12158, IPR021994): Protein of unknown function (DUF3592) AJAP1_PANP_C (PF15298, IPR029198): AJAP1/PANP C-terminus
71	SDCBP	interactor	6	0.200	238.163	PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
72	SFPQ	oncoprotein	4	0.333	71.249	GRP (PF07172, IPR010800): Glycine rich protein family Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1 CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
73	SMG1	interactor	4	0.667	1.253	Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein KxDL (PF10241, IPR019371): Uncharacterized conserved protein XhlA (PF10779, IPR019715): Haemolysin XhlA PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase SMG1 (PF15785, IPR031559): Serine/threonine-protein kinase smg-1
74	SQSTM1	oncoprotein	22	0.267	303.182	PB1 (PF00564, IPR000270, SM00666): PB1 domain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type UBA_5 (PF16577, IPR015940): UBA domain
75	SRF	interactor	2	0	0	SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain)
76	SSB	interactor	4	0.667	3.130	HMA (PF00403, IPR006121): Heavy-metal-associated domain La (PF05383, IPR006630, SM00715): La domain Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family Ribosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 (PF08777, IPR014886): RNA binding motif
77	TJP1	interactor	8	0.393	25.402	DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) SH3_2 (PF07653, IPR011511): Variant SH3 domain ZU5 (PF00791, IPR000906, SM00218): ZU5 domain Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase RPOL_N (PF14700, IPR029262): DNA-directed RNA polymerase N-terminal
78	TMEM17	interactor	9	0.361	152.914	Transmemb_17 (PF09799, IPR019184): Predicted membrane protein DUF3043 (PF11241, IPR021403): Protein of unknown function (DUF3043)
79	TMEM208	interactor	1	0	0	DUF788 (PF05620, IPR008506): Protein of unknown function (DUF788)
80	TRAPPC13	interactor	1	0	0	DUF974 (PF06159, IPR010378): Protein of unknown function (DUF974) Transglut_C (PF00927, IPR008958): Transglutaminase family, C-terminal ig like domain Trs65 (PF12735, IPR024662): TRAPP trafficking subunit Trs65
81	TSC22D1	suppressor	2	0	0	SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region TSC22 (PF01166, IPR000580): TSC-22/dip/bun family ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
82	TSPAN3	interactor	3	0.667	6.992	Hum_adeno_E3A (PF05393, IPR008652): Human adenovirus early E3A glycoprotein Tetraspannin (PF00335, IPR018499): Tetraspanin family
83	TTR	interactor	2	0	0	Transthyretin (PF00576, IPR023416, SM00095): HIUase/Transthyretin family
84	USP21	interactor	5	0.667	1.067	UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
85	VHL	suppressor	9	0.464	18.548	Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): VHL beta domain VHL_C (PF17211): VHL box domain
86	VKORC1	interactor	4	1.000	0	VKOR (PF07884, IPR012932, SM00756): Vitamin K epoxide reductase family
87	XPO1	interactor	20	0.232	197.496	CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
88	YWHAE	oncoprotein	15	0.333	232.015	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
89	YWHAH	protein found in more fusions	19	0.353	115.099	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
90	YWHAZ	protein found in more fusions	17	0.392	67.105	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
91	ZNF609	interactor	1	0	0	Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain DUF4551 (PF15087, IPR027878): Protein of unknown function (DUF4551)

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