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Fusion ID: Protein names:	967 339166
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Visualization interactions

Cytoscape Web for: parental proteins LOC339166, CD63 (from a repository: Fri May 19 09:06:43 2017)

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Statistics and Network structure information

Statistic of PPI	Value(s)
The number of interactors (fusion and proteins)	22
The number (and %) of the onco-proteins	4 (18.18 %)
The number (and %) of the tumor suppressors	2 (9.09 %)
Total number of binary PPIs (saturation %)	54 (23.38 %)
The number (and %) of affected PPIs	20 (37.04 %)
The number of possible different fusions	2
PPI diameter	2
PPI radius	inf
The average degree of PPI	4.545
Assortativity coefficient	-0.2126
The network average Clustering coefficient	0.596
The number (and %) of a zero Clustering coefficients	3 (13.64 %)
The number (and %) of a zero Betweenness Centrality	10 (45.45 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: CD63,LOC339166	All fusions
Proteins found in more fusions	LGALS3 (see 2 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	CD63	parental protein	20	0.158	265.500	Tetraspannin (PF00335, IPR018499): Tetraspanin family DUF4282 (PF14110, IPR025557): Domain of unknown function (DUF4282)
2	LOC339166	interactor	0	0	0	Sulfotransfer_1 (PF00685, IPR000863): Sulfotransferase domain WSC (PF01822, IPR002889, SM00321): WSC domain
3	ATP6V1B1	interactor	2	1.000	0	ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain DUF3533 (PF12051, IPR022703): Protein of unknown function (DUF3533)
4	CD81	interactor	8	0.571	5.667	Tetraspannin (PF00335, IPR018499): Tetraspanin family
5	CD82	suppressor	7	0.476	11.000	Tetraspannin (PF00335, IPR018499): Tetraspanin family
6	CD9	oncoprotein	8	0.464	11.667	Tetraspannin (PF00335, IPR018499): Tetraspanin family
7	FAM134C	interactor	1	0	0	Reticulon (PF02453, IPR003388): Reticulon
8	HLA-DMB	interactor	3	1.000	0	MHC_II_beta (PF00969, IPR000353, SM00921): Class II histocompatibility antigen, beta domain C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
9	HLA-DOB	interactor	2	1.000	0	MHC_II_beta (PF00969, IPR000353, SM00921): Class II histocompatibility antigen, beta domain C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
10	HLA-DRA	interactor	3	1.000	0	MHC_II_alpha (PF00993, IPR001003, SM00920): Class II histocompatibility antigen, alpha domain C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain C1-set_C (PF16196, IPR032431): C1-set C-terminal domain
11	ITGB1	suppressor	6	0.467	5.167	EGF_2 (PF07974, IPR013111): EGF-like domain Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain Integrin_beta (PF00362, IPR002369, SM00187): Integrin, beta chain PSI_integrin (PF17205): Integrin plexin domain
12	KIT	oncoprotein	3	1.000	0	ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain
13	LGALS3	oncoprotein	5	0.833	0.333	Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
14	LGALS8	interactor	5	0.400	4.333	Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
15	LGALS9	interactor	5	0.600	2.667	Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin Peptidase_C62 (PF12380, IPR024348): Gill-associated viral 3C-like peptidase
16	PTGFRN	interactor	7	0.476	8.167	V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain
17	RNF13	interactor	4	0.500	2.167	DNA_ligase_ZBD (PF03119, IPR004149): NAD-dependent DNA ligase C4 zinc finger domain PA (PF02225, IPR003137): PA domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain FAM176 (PF14851): FAM176 family STAC2_u1 (PF16664): Unstructured on SH3 and cysteine-rich domain-containing protein 2
18	SDC1	oncoprotein	2	1.000	0	Herpes_TAF50 (PF03326, IPR004998): Herpesvirus transcription activation factor (transactivator) Syndecan (PF01034, IPR027789): Syndecan domain DUF3592 (PF12158, IPR021994): Protein of unknown function (DUF3592) AJAP1_PANP_C (PF15298, IPR029198): AJAP1/PANP C-terminus
19	SDCBP	interactor	4	0.500	2.667	PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
20	SRF	interactor	2	0	0	SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain)
21	TSPAN3	interactor	3	0.667	0.667	Hum_adeno_E3A (PF05393, IPR008652): Human adenovirus early E3A glycoprotein Tetraspannin (PF00335, IPR018499): Tetraspanin family
22	VKORC1	interactor	4	1.000	0	VKOR (PF07884, IPR012932, SM00756): Vitamin K epoxide reductase family

B a c k t o T o p ⇑

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Visualization interactions

Statistics and Network structure information

List of the fusions

List of active interactors