1 |
PRDX6 | parental protein | 75 | 0.076 | 4114.480 | AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin |
2 |
AHSA1 | interactor | 3 | 1.000 | 0 | Aha1_N (PF09229, IPR015310, SM01000): Activator of Hsp90 ATPase, N-terminal AHSA1 (PF08327, IPR013538): Activator of Hsp90 ATPase homolog 1-like protein |
3 |
AKR1B1 | suppressor | 8 | 0.393 | 14.167 | Aldo_ket_red (PF00248, IPR023210): Aldo/keto reductase family |
4 |
APEX1 | interactor | 6 | 0.533 | 4.341 | Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family |
5 |
ASB12 | interactor | 2 | 1.000 | 0 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_3 (PF13606, IPR002110): Ankyrin repeat SOCS_box (PF07525, IPR001496): SOCS box |
6 |
ASB3 | interactor | 1 | 0 | 0 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) SOCS_box (PF07525, IPR001496): SOCS box |
7 |
ASS1 | suppressor | 9 | 0.536 | 7.389 | Arginosuc_synth (PF00764, IPR001518): Arginosuccinate synthase |
8 |
ATP6V1A | interactor | 6 | 0.333 | 7.250 | ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab_Xtn (PF16886, IPR031686): ATPsynthase alpha/beta subunit N-term extension |
9 |
C11orf54 | interactor | 5 | 0.500 | 3.333 | DUF1907 (PF08925, IPR015021, SM01168): Domain of Unknown Function (DUF1907) |
10 |
C11orf58 | interactor | 4 | 0.667 | 1.333 | DUF3408 (PF11888, IPR021823): Protein of unknown function (DUF3408) SMAP (PF15477, IPR028124): Small acidic protein family |
11 |
CAPG | suppressor | 1 | 0 | 0 | Gelsolin (PF00626, IPR007123): Gelsolin repeat |
12 |
CASP10 | interactor | 4 | 1.000 | 0 | DED (PF01335, IPR001875, SM00031): Death effector domain Peptidase_C14 (PF00656, IPR011600): Caspase domain |
13 |
CASP8 | suppressor | 5 | 0.833 | 0.667 | DED (PF01335, IPR001875, SM00031): Death effector domain Peptidase_C14 (PF00656, IPR011600): Caspase domain |
14 |
CD2AP | protein found in more fusions | 7 | 0.400 | 7.900 | SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil |
15 |
CDK2 | suppressor | 13 | 0.500 | 18.880 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
16 |
CUL1 | suppressor | 12 | 0.545 | 11.813 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
17 |
CUL7 | protein found in more fusions | 13 | 0.318 | 27.111 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
18 |
ECI1 | interactor | 1 | 0 | 0 | ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase |
19 |
ENOPH1 | interactor | 1 | 0 | 0 | Hydrolase (PF00702, IPR023214): haloacid dehalogenase-like hydrolase |
20 |
FN1 | oncoprotein | 11 | 0.418 | 19.594 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
21 |
GLO1 | interactor | 6 | 0.400 | 7.833 | Glyoxalase (PF00903, IPR004360): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily |
22 |
GPI | interactor | 11 | 0.455 | 18.738 | PGI (PF00342, IPR001672): Phosphoglucose isomerase |
23 |
GPX4 | interactor | 4 | 0.833 | 0.500 | GSHPx (PF00255, IPR000889): Glutathione peroxidase |
24 |
GRHPR | interactor | 4 | 0.667 | 1.500 | 2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain |
25 |
GSTO1 | interactor | 5 | 0.600 | 2.786 | GST_N_3 (PF13417, IPR004045): Glutathione S-transferase, N-terminal domain GST_C_3 (PF14497, IPR004046): Glutathione S-transferase, C-terminal domain |
26 |
GSTZ1 | interactor | 2 | 0 | 0 | Tom37 (PF10568, IPR019564): Outer mitochondrial membrane transport complex protein GST_N_3 (PF13417, IPR004045): Glutathione S-transferase, N-terminal domain GST_C_3 (PF14497, IPR004046): Glutathione S-transferase, C-terminal domain |
27 |
H2AFX | suppressor | 4 | 0.667 | 1.333 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A |
28 |
HDAC5 | protein found in more fusions | 7 | 0.733 | 1.006 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4 |
29 |
HINT1 | suppressor | 9 | 0.464 | 11.233 | HIT (PF01230, IPR001310): HIT domain |
30 |
HNF4G | interactor | 1 | 0 | 0 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
31 |
HSPB1 | oncoprotein | 14 | 0.410 | 29.057 | HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family |
32 |
HUWE1 | oncoprotein | 12 | 0.436 | 19.272 | BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414) |
33 |
ISG15 | suppressor | 8 | 0.321 | 9.852 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
34 |
ITGA4 | interactor | 12 | 0.491 | 16.907 | FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha |
35 |
LYPLA1 | interactor | 6 | 0.600 | 2.286 | Abhydrolase_2 (PF02230, IPR003140): Phospholipase/Carboxylesterase |
36 |
MDH1 | interactor | 9 | 0.389 | 14.738 | Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain |
37 |
NCF2 | interactor | 1 | 0 | 0 | PB1 (PF00564, IPR000270, SM00666): PB1 domain TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat SH3_1 (PF00018, IPR001452, SM00326): SH3 domain TPR_16 (PF13432): Tetratricopeptide repeat |
38 |
NIT2 | suppressor | 7 | 0.333 | 12.000 | CN_hydrolase (PF00795, IPR003010): Carbon-nitrogen hydrolase |
39 |
NPM1 | suppressor | 17 | 0.358 | 47.076 | Nucleoplasmin (PF03066): Nucleoplasmin SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain |
40 |
NR4A1 | suppressor | 2 | 1.000 | 0 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
41 |
NTRK1 | oncoprotein | 26 | 0.237 | 172.063 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
42 |
ORM2 | interactor | 1 | 0 | 0 | Lipocalin (PF00061, IPR000566): Lipocalin / cytosolic fatty-acid binding protein family |
43 |
OXCT1 | interactor | 12 | 0.273 | 33.300 | CoA_trans (PF01144, IPR004165, SM00882): Coenzyme A transferase |
44 |
PAXIP1 | interactor | 4 | 0.500 | 2.167 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase SURF6 (PF04935, IPR007019): Surfeit locus protein 6 DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance PTCB-BRCT (PF12738, IPR001357): twin BRCT domain BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT (PF16759, IPR031916): DNA ligase 3 BRCT domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
45 |
PCNA | oncoprotein | 12 | 0.473 | 13.357 | PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain |
46 |
PFAS | interactor | 2 | 1.000 | 0 | AIRS_C (PF02769, IPR010918): AIR synthase related protein, C-terminal domain GATase_5 (PF13507): CobB/CobQ-like glutamine amidotransferase domain |
47 |
PGM1 | interactor | 10 | 0.400 | 21.686 | PGM_PMM_I (PF02878, IPR005844): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II (PF02879, IPR005845): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III (PF02880, IPR005846): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV (PF00408, IPR005843): Phosphoglucomutase/phosphomannomutase, C-terminal domain |
48 |
PITRM1 | interactor | 2 | 1.000 | 0 | M16C_assoc (PF08367, IPR013578): Peptidase M16C associated Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16) Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain |
49 |
PKM | oncoprotein | 18 | 0.340 | 56.831 | PK (PF00224, IPR015793): Pyruvate kinase, barrel domain PK_C (PF02887, IPR015795): Pyruvate kinase, alpha/beta domain |
50 |
PPARD | oncoprotein | 2 | 0 | 0 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
51 |
PRDX1 | oncoprotein | 16 | 0.305 | 38.198 | AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin |
52 |
PRDX2 | interactor | 16 | 0.350 | 52.575 | AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin |
53 |
PRDX5 | interactor | 8 | 0.500 | 9.900 | Redoxin (PF08534, IPR013740): Redoxin NAD_binding_10 (PF13460, IPR016040): NAD(P)H-binding |
54 |
PTGR1 | interactor | 5 | 0.500 | 2.900 | ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase ADH_N_2 (PF16884): N-terminal domain of oxidoreductase |
55 |
RANGAP1 | protein found in more fusions | 6 | 0.500 | 3.033 | RanGAP1_C (PF07834, IPR009109): RanGAP1 C-terminal domain SDA1 (PF05285, IPR007949): SDA1 LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat |
56 |
RARA | oncoprotein | 4 | 1.000 | 0 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
57 |
RDX | interactor | 3 | 1.000 | 0 | ERM (PF00769, IPR011259): Ezrin/radixin/moesin family FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain |
58 |
RHOA | suppressor | 4 | 0.833 | 0.667 | Ras (PF00071, IPR001806, SM00173): Ras family |
59 |
SCPEP1 | interactor | 2 | 1.000 | 0 | Peptidase_S10 (PF00450, IPR001563): Serine carboxypeptidase |
60 |
SDHB | suppressor | 4 | 0.500 | 1.667 | Fer2_3 (PF13085, IPR025192): 2Fe-2S iron-sulfur cluster binding domain Fer4_8 (PF13183, IPR017896): 4Fe-4S dicluster domain Fer4_17 (PF13534): 4Fe-4S dicluster domain |
61 |
SERPINB5 | suppressor | 7 | 0.429 | 10.400 | Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor) |
62 |
SPR | interactor | 7 | 0.667 | 3.567 | adh_short (PF00106, IPR002198): short chain dehydrogenase |
63 |
SSU72 | interactor | 2 | 1.000 | 0 | Ssu72 (PF04722, IPR006811): Ssu72-like protein |
64 |
STAU1 | protein found in more fusions | 8 | 0.667 | 4.486 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain |
65 |
STH | interactor | 1 | 0 | 0 | NA |
66 |
SUCLG2 | interactor | 3 | 0.667 | 1.000 | ATP-grasp_2 (PF08442, IPR013650): ATP-grasp domain Ligase_CoA (PF00549, IPR005811): CoA-ligase |
67 |
TERF1 | interactor | 10 | 0.444 | 11.822 | TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
68 |
TERF2IP | protein found in more fusions | 6 | 0.800 | 1.000 | BRF1 (PF07741, IPR011665): Brf1-like TBP-binding domain Histone_HNS (PF00816, IPR001801): H-NS histone family Myb_DNA-bind_2 (PF08914, IPR015010): Rap1 Myb domain Rap1_C (PF11626, IPR021661): TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391) BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain |
69 |
TIMM9 | interactor | 3 | 0.667 | 0.500 | zf-Tim10_DDP (PF02953, IPR004217): Tim10/DDP family zinc finger |
70 |
TMED10 | interactor | 3 | 0.667 | 0.667 | EMP24_GP25L (PF01105, IPR009038): emp24/gp25L/p24 family/GOLD |
71 |
TMEM189 | interactor | 3 | 0.667 | 0.500 | MARVEL (PF01284, IPR008253): Membrane-associating domain TMEM189_B_dmain (PF10520, IPR019547): B domain of TMEM189, localisation domain |
72 |
TPI1 | interactor | 20 | 0.263 | 93.407 | TIM (PF00121, IPR000652): Triosephosphate isomerase |
73 |
UCHL5 | oncoprotein | 10 | 0.556 | 8.025 | Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1 |
74 |
VCAM1 | interactor | 8 | 0.536 | 6.055 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
75 |
WDR1 | interactor | 8 | 0.464 | 9.852 | eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |