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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins PTPRM, PIGL (from a repository: Fri Aug 9 13:39:32 2019)

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)5
The number (and %) of the onco-proteins1 (20.00 %)
The number (and %) of the tumor suppressors2 (40.00 %)
Total number of binary PPIs (saturation %)5 (50.00 %)
The number (and %) of affected PPIs3 (60.00 %)
The number of possible different fusions3
PPI diameter2
PPI radiusinf
The average degree of PPI1.200
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients5 (100.00 %)
The number (and %) of a zero Betweenness Centrality4 (80.00 %)


List of the fusions

PPI for parental proteins: PTPRM,PIGL All fusions
Proteins found in more fusions RACK1 (see 3 fusions); MEIS2 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 PTPRMparental protein202.000fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
MAM (PF00629, IPR000998, SM00137): MAM domain, meprin/A5/mu
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
ECSCR (PF15820, IPR026247): Endothelial cell-specific chemotaxis regulator
2 PIGLparental protein100PIG-L (PF02585, IPR003737): GlcNAc-PI de-N-acetylase
3 CTNND1suppressor100Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Ebp2 (PF05890, IPR008610): Eukaryotic rRNA processing protein EBP2
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
4 MEIS2protein found in more fusions200Homeobox_KN (PF05920, IPR008422): Homeobox KN domain
Meis_PKNOX_N (PF16493, IPR032453): N-terminal of Homeobox Meis and PKNOX1
5 RACK1suppressor200WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain

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