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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins CDCP1, ABCG2 (from a repository: Thu Jul 11 22:24:00 2019)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)11
The number (and %) of the onco-proteins1 (9.09 %)
The number (and %) of the tumor suppressors1 (9.09 %)
Total number of binary PPIs (saturation %)14 (25.45 %)
The number (and %) of affected PPIs9 (64.29 %)
The number of possible different fusions1
PPI diameter2
PPI radiusinf
The average degree of PPI2.364
Assortativity coefficient0.1899
The network average Clustering coefficient0.479
The number (and %) of a zero Clustering coefficients5 (45.45 %)
The number (and %) of a zero Betweenness Centrality9 (81.82 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: CDCP1,ABCG2 All fusions
Proteins found in more fusions

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 CDCP1parental protein306.000CUB (PF00431, IPR000859, SM00042): CUB domain
2 ABCG2parental protein60.26722.000ABC2_membrane (PF01061, IPR013525): ABC-2 type transporter
ABC_tran (PF00005, IPR003439): ABC transporter
ABC2_membrane_3 (PF12698): ABC-2 family transporter protein
AAA_21 (PF13304, IPR003959): AAA domain, putative AbiEii toxin, Type IV TA system
SbcCD_C (PF13558): Putative exonuclease SbcCD, C subunit
3 ALBinteractor100Serum_albumin (PF00273, IPR014760, SM00103): Serum albumin family
4 CLK1interactor200PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region
Pkinase (PF00069, IPR000719): Protein kinase domain
5 DBN1oncoprotein31.0000Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
6 GOLT1Binteractor21.0000Got1 (PF04178, IPR007305): Got1/Sft2-like family
7 MYO5Cinteractor31.0000DIL (PF01843, IPR018444, SM01132): DIL domain
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Pilus_CpaD (PF09476, IPR019027): Pilus biogenesis CpaD protein (pilus_cpaD)
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
YtxH (PF12732, IPR024623): YtxH-like protein
Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
8 PCDH7interactor21.0000Cadherin_2 (PF08266, IPR013164): Cadherin-like
Protocadherin (PF08374, IPR013585): Protocadherin
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG
Cadherin_3 (PF16184): Cadherin-like
9 RAB7Asuppressor100Ras (PF00071, IPR001806, SM00173): Ras family
10 SDCBPinteractor100PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
11 SYNPOinteractor31.0000Calsarcin (PF05556, IPR008438): Calcineurin-binding protein (Calsarcin)

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