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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins TM9SF2, LINC02455 (from a repository: Sun Dec 23 19:09:00 2018)

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)10
The number (and %) of the onco-proteins0 (0.00 %)
The number (and %) of the tumor suppressors1 (10.00 %)
Total number of binary PPIs (saturation %)12 (26.67 %)
The number (and %) of affected PPIs8 (66.67 %)
The number of possible different fusions2
PPI diameter2
PPI radiusinf
The average degree of PPI2.200
Assortativity coefficient-0.6630
The network average Clustering coefficient0.361
The number (and %) of a zero Clustering coefficients5 (50.00 %)
The number (and %) of a zero Betweenness Centrality8 (80.00 %)


List of the fusions

PPI for parental proteins: LINC02455,TM9SF2 All fusions
Proteins found in more fusions SMAD4 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 LINC02455interactor000NA
2 TM9SF2parental protein80.10747.000FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
EMP70 (PF02990, IPR004240): Endomembrane protein 70
3 ATP1B3interactor100Na_K-ATPase (PF00287, IPR000402): Sodium / potassium ATPase beta chain
4 MMGT1interactor21.0000MMgT (PF10270, IPR018937): Membrane magnesium transporter
5 RPN2interactor21.0000Ribophorin_II (PF05817, IPR008814): Oligosaccharyltransferase subunit Ribophorin II
6 SLC25A3interactor100Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
7 SMAD4suppressor200MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
8 SRSF7interactor100RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TP2 (PF01254, IPR000678): Nuclear transition protein 2
zf-CCHC (PF00098, IPR001878): Zinc knuckle
9 TCTN3interactor40.5003.000DUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619)
10 UNC93B1interactor21.0000UNC-93 (PF05978, IPR010291): Ion channel regulatory protein UNC-93
Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup
DUF4131 (PF13567, IPR025405): Domain of unknown function (DUF4131)

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