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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins EBAG9, ND2 (from a repository: Sat Jul 27 07:50:56 2019)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)11
The number (and %) of the onco-proteins1 (9.09 %)
The number (and %) of the tumor suppressors2 (18.18 %)
Total number of binary PPIs (saturation %)14 (25.45 %)
The number (and %) of affected PPIs9 (64.29 %)
The number of possible different fusions2
PPI diameter5
PPI radius3
The average degree of PPI2.182
Assortativity coefficient0.1090
The network average Clustering coefficient0.255
The number (and %) of a zero Clustering coefficients7 (63.64 %)
The number (and %) of a zero Betweenness Centrality6 (54.55 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: MT-ND2,EBAG9 All fusions
Proteins found in more fusions NEDD4 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 ND2parental protein60.13365.000NA
2 EBAG9parental protein3034.000DUF3395 (PF11875, IPR024586): Domain of unknown function (DUF3395)
3 GRIN1interactor100ANF_receptor (PF01094, IPR001828): Receptor family ligand binding region
Lig_chan (PF00060, IPR001320): Ligand-gated ion channel
CaM_bdg_C0 (PF10562, IPR018882): Calmodulin-binding domain C0 of NMDA receptor NR1 subunit
Lig_chan-Glu_bd (PF10613, IPR019594, SM00918): Ligated ion channel L-glutamate- and glycine-binding site
4 NDUFA11interactor21.00007kD_coat (PF02495, IPR003411): 7kD viral coat protein
Tim17 (PF02466, IPR003397): Tim17/Tim22/Tim23/Pmp24 family
5 NEDD4suppressor3042.000Rota_NS26 (PF01525, IPR002512): Rotavirus NS26
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
6 SRConcoprotein3048.000Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
7 STK11suppressor100Pkinase (PF00069, IPR000719): Protein kinase domain
8 TIMMDC1interactor21.0000Tim17 (PF02466, IPR003397): Tim17/Tim22/Tim23/Pmp24 family
9 TMEM17interactor100Transmemb_17 (PF09799, IPR019184): Predicted membrane protein
DUF3043 (PF11241, IPR021403): Protein of unknown function (DUF3043)
10 TMEM216interactor100Transmemb_17 (PF09799, IPR019184): Predicted membrane protein
11 YME1L1interactor30.6671.000AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
Peptidase_M41 (PF01434, IPR000642): Peptidase family M41

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