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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins DGKA, SYNGR1 (from a repository: Wed Jan 8 16:28:06 2020)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)9
The number (and %) of the onco-proteins0 (0.00 %)
The number (and %) of the tumor suppressors2 (22.22 %)
Total number of binary PPIs (saturation %)10 (27.78 %)
The number (and %) of affected PPIs7 (70.00 %)
The number of possible different fusions2
PPI diameter2
PPI radiusinf
The average degree of PPI1.556
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients9 (100.00 %)
The number (and %) of a zero Betweenness Centrality7 (77.78 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: SYNGR1,DGKA All fusions
Proteins found in more fusions SMAD2 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 SYNGR1parental protein306.000MARVEL (PF01284, IPR008253): Membrane-associating domain
2 DGKAparental protein4012.000C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
DAGK_acc (PF00609, IPR000756, SM00045): Diacylglycerol kinase accessory domain
DAGK_cat (PF00781, IPR001206, SM00046): Diacylglycerol kinase catalytic domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
DAG_kinase_N (PF14513, IPR029477): Diacylglycerol kinase N-terminus
3 CREB3interactor200bZIP_1 (PF00170, IPR004827): bZIP transcription factor
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
4 FATE1interactor100Miff (PF05644, IPR008518): Mitochondrial and peroxisomal fission factor Mff
5 FUSsuppressor100Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Limkain-b1 (PF11608, IPR024582): Limkain b1
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
6 HMOX2interactor100Heme_oxygenase (PF01126, IPR016053): Heme oxygenase
7 IL21interactor100IL15 (PF02372, IPR003443): Interleukin 15
8 ORC5interactor200AAA_16 (PF13191): AAA ATPase domain
ORC5_C (PF14630, IPR020796): Origin recognition complex (ORC) subunit 5 C-terminus
9 SMAD2suppressor200MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain

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