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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)98
The number (and %) of the onco-proteins16 (16.33 %)
The number (and %) of the tumor suppressors9 (9.18 %)
Total number of binary PPIs (saturation %)399 (8.39 %)
The number (and %) of affected PPIs97 (24.31 %)
The number of possible different fusions11
PPI diameter4
PPI radius2
The average degree of PPI7.653
Assortativity coefficient-0.3256
The network average Clustering coefficient0.390
The number (and %) of a zero Clustering coefficients20 (20.41 %)
The number (and %) of a zero Betweenness Centrality15 (15.31 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: TMEM67,SCAMP3 All fusions
Proteins found in more fusions APP (see 4 fusions); BAG3 (see 4 fusions); CKAP4 (see 5 fusions); EGFR (see 2 fusions); TSG101 (see 2 fusions); SFTPC (see 1 fusions); RPA1 (see 1 fusions); PSMC5 (see 2 fusions); BCAP31 (see 3 fusions); NEDD4 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 TMEM67parental protein530.0422873.309Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like
NCD3G (PF07562, IPR011500): Nine Cysteines Domain of family 3 GPCR
Tme5_EGF_like (PF09064, IPR015149): Thrombomodulin like fifth domain, EGF-like
Meckelin (PF09773, IPR019170): Meckelin (Transmembrane protein 67)
hEGF (PF12661, IPR013032): Human growth factor-like EGF
2 SCAMP3parental protein440.0922555.986SCAMP (PF04144, IPR007273): SCAMP family
3 ABCD3interactor60.13374.667ABC_membrane_2 (PF06472, IPR010509): ABC transporter transmembrane region 2
ABC_tran (PF00005, IPR003439): ABC transporter
4 AKAP1interactor3012.926TUDOR (PF00567, IPR002999, SM00333): Tudor domain
RII_binding_1 (PF10522, IPR018459): RII binding domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
5 APPprotein found in more fusions150.165158.846APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
6 ATP1B4interactor31.0000Gcd10p (PF04189, IPR007316): Gcd10p family
Na_K-ATPase (PF00287, IPR000402): Sodium / potassium ATPase beta chain
7 ATP4Ainteractor31.0000Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus
Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus
E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
H-K_ATPase_N (PF09040, IPR015127): Gastric H+/K+-ATPase, N terminal domain
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
HAD (PF12710): haloacid dehalogenase-like hydrolase
Cation_ATPase (PF13246): Cation transport ATPase (P-type)
8 ATP5MGinteractor50.7004.068ATP-synt_G (PF04718, IPR006808): Mitochondrial ATP synthase g subunit
9 ATP6AP1interactor40.3338.722ATP-synt_S1 (PF05827, IPR024722): Vacuolar ATP synthase subunit S1 (ATP6S1)
10 ATP6AP2interactor90.32145.186Phosphodiest (PF01663, IPR002591): Type I phosphodiesterase / nucleotide pyrophosphatase
Renin_r (PF07850, IPR012493): Renin receptor-like protein
11 ATP6V0A1interactor40.16756.138V_ATPase_I (PF01496, IPR002490): V-type ATPase 116kDa subunit family
12 ATP6V1E1interactor40.33323.956vATP-synt_E (PF01991, IPR002842): ATP synthase (E/31 kDa) subunit
13 BAG3oncoprotein50.50018.630BAG (PF02179, IPR003103, SM00264): BAG domain
WW (PF00397, IPR001202, SM00456): WW domain
14 BCAP31protein found in more fusions110.378195.417Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
15 CAMLGinteractor307.425CAML (PF14963, IPR016719): Calcium signal-modulating cyclophilin ligand
16 CCDC47interactor80.28661.184DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682)
STAC2_u1 (PF16664): Unstructured on SH3 and cysteine-rich domain-containing protein 2
17 CCDC8interactor130.106114.211Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA
18 CD27interactor100TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
19 CDC73suppressor21.0000CDC73_C (PF05179, IPR007852): RNA pol II accessory factor, Cdc73 family, C-terminal
CDC73_N (PF16050, IPR032041): Paf1 complex subunit CDC73 N-terminal
20 CKAP4protein found in more fusions110.156159.652DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
FPP (PF05911, IPR008587): Filament-like plant protein, long coiled-coil
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
21 CLN3interactor90.27846.814CLN3 (PF02487, IPR003492): CLN3 protein
22 DDOSTinteractor100.46748.459DDOST_48kD (PF03345, IPR005013): Oligosaccharyltransferase 48 kDa subunit beta
23 DDX54interactor4029.036DBP10CT (PF08147, IPR012541, SM01123): DBP10CT (NUC160) domain
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Herpes_DNAp_acc (PF04929, IPR007013): Herpes DNA replication accessory factor
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
24 EGFRoncoprotein310.147739.142Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
25 EMC1interactor70.47632.251DUF1620 (PF07774, IPR011678): Protein of unknown function (DUF1620)
PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat
PQQ_2 (PF13360, IPR002372): PQQ-like domain
26 EMC2interactor80.46422.309TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_19 (PF14559): Tetratricopeptide repeat
Alkyl_sulf_dimr (PF14863, IPR029228): Alkyl sulfatase dimerisation
27 EMC3interactor80.39352.026DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
28 EPHA2suppressor60.6006.920fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
29 ERLIN2interactor110.27382.802Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
DUF4346 (PF14251, IPR025595): Domain of unknown function (DUF4346)
30 FBXO6interactor240.145436.234FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
31 GBAinteractor50.50010.605Glyco_hydro_30 (PF02055, IPR001139): Glycosyl hydrolase family 30 TIM-barrel domain
Glyco_hydro_30C (PF17189): Glycosyl hydrolase family 30 beta sandwich domain
32 HAUS2interactor30.33311.636DpnII (PF04556, IPR007637): DpnII restriction endonuclease
HAUS2 (PF15003, IPR028346): HAUS augmin-like complex subunit 2
33 HGSinteractor80.50046.649FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VHS (PF00790, IPR002014, SM00288): VHS domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate
PIEZO (PF15917, IPR031805): Piezo
34 HM13interactor3022.128Peptidase_A22B (PF04258, IPR007369): Signal peptide peptidase
DUF4345 (PF14248, IPR025597): Domain of unknown function (DUF4345)
35 HSPA5oncoprotein160.267264.246HSP70 (PF00012, IPR013126): Hsp70 protein
36 IPO5interactor50.8002.288HEAT (PF02985, IPR000357): HEAT repeat
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
AAA_30 (PF13604): AAA domain
HEAT_2 (PF13646): HEAT repeats
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
37 ITCHinteractor60.6003.633C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
38 KCNC4interactor100Ion_trans (PF00520, IPR005821): Ion transport protein
BTB_2 (PF02214, IPR003131): BTB/POZ domain
Potassium_chann (PF11404, IPR021105): Potassium voltage-gated channel
39 LNPKinteractor30.3335.828zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein
DUF4153 (PF13687, IPR025291): Domain of unknown function (DUF4153)
40 LYPD3oncoprotein30.6671.854DUF753 (PF05444, IPR008472): Protein of unknown function (DUF753)
UPAR_LY6 (PF00021, IPR001526): u-PAR/Ly-6 domain
41 MAGT1interactor60.40045.721OST3_OST6 (PF04756, IPR021149): OST3 / OST6 family, transporter family
42 MBOAT1interactor21.0000MBOAT (PF03062, IPR004299): MBOAT, membrane-bound O-acyltransferase family
CBP_BcsF (PF11120, IPR019995): Cellulose biosynthesis protein BcsF
DUF3329 (PF11808, IPR021766): Domain of unknown function (DUF3329)
43 MMP15interactor100Orbi_VP6 (PF01516, IPR001399): Orbivirus helicase VP6
Peptidase_M10 (PF00413, IPR001818): Matrixin
PG_binding_1 (PF01471, IPR002477): Putative peptidoglycan binding domain
Hemopexin (PF00045, IPR018487, SM00120): Hemopexin
DUF3377 (PF11857, IPR021805): Domain of unknown function (DUF3377)
44 MPLKIPinteractor21.0000MPLKIP (PF15502, IPR028265): M-phase-specific PLK1-interacting protein
45 NCSTNinteractor70.47625.662Nicastrin (PF05450, IPR008710): Nicastrin
Ost4 (PF10215, IPR018943): Oligosaccaryltransferase
46 NEDD4suppressor100.36165.464Rota_NS26 (PF01525, IPR002512): Rotavirus NS26
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
47 NSA2oncoprotein201.618Ribosomal_S8e (PF01201, IPR022309): Ribosomal protein S8e
RRP14 (PF15459, IPR029188): 60S ribosome biogenesis protein Rrp14
48 NTRK1oncoprotein410.1141186.169I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
49 OCIAD1interactor31.0000OCIA (PF07051, IPR009764): Ovarian carcinoma immunoreactive antigen (OCIA)
50 ORC1interactor21.0000AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
BAH (PF01426, IPR001025, SM00439): BAH domain
Cdc6_C (PF09079, IPR015163, SM01074): CDC6, C terminal winged helix domain
51 PDCD11interactor306.273DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain
Suf (PF05843, IPR008847): Suppressor of forked protein (Suf)
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
52 PGRMC2suppressor4011.270Cyt-b5 (PF00173, IPR001199, SM01117): Cytochrome b5-like Heme/Steroid binding domain
53 PREBinteractor201.618WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
54 PSMC3interactor130.66736.288AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
DUF3713 (PF12506, IPR022186): Protein of unknown function (DUF3713)
JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
55 PSMC4interactor90.9722.176AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
NTPase_1 (PF03266, IPR004948): NTPase
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
AAA_16 (PF13191): AAA ATPase domain
56 PSMC5protein found in more fusions140.62844.787AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
Laminin_II (PF06009, IPR010307): Laminin Domain II
RILP (PF11461, IPR021563): Rab interacting lysosomal protein
AAA_16 (PF13191): AAA ATPase domain
57 PSMC6interactor110.8446.224AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
AAA_2 (PF07724, IPR013093): AAA domain (Cdc48 subfamily)
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain
58 PSMD1interactor130.59040.554PA26 (PF04636, IPR006730): PA26 p53-induced protein (sestrin)
PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
HEAT_2 (PF13646): HEAT repeats
59 PSMD14interactor90.9722.176JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
60 PSMD2oncoprotein130.55159.695PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
THAP (PF05485, IPR006612, SM00980): THAP domain
HEAT_2 (PF13646): HEAT repeats
61 PSMD4interactor140.52791.238UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
62 PTPRKsuppressor204.428fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
MAM (PF00629, IPR000998, SM00137): MAM domain, meprin/A5/mu
Protocadherin (PF08374, IPR013585): Protocadherin
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
63 RAB2Aoncoprotein80.35763.535Ras (PF00071, IPR001806, SM00173): Ras family
64 RNF126interactor40.6671.601Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
zinc_ribbon_9 (PF14369): zinc-ribbon
65 RPA1suppressor140.423107.810Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
66 RPA2oncoprotein110.45569.236RPA_C (PF08784, IPR014892): Replication protein A C terminal
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
67 RPA3interactor100.58330.679Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
68 RPN1oncoprotein160.300191.315Ribophorin_I (PF04597, IPR007676): Ribophorin I
CtIP_N (PF10482, IPR019518): Tumour-suppressor protein CtIP N-terminal domain
69 SDHAsuppressor40.3334.891FAD_binding_2 (PF00890, IPR003953): FAD binding domain
Succ_DH_flav_C (PF02910, IPR015939): Fumarate reductase flavoprotein C-term
70 SEC11Ainteractor305.047Peptidase_S24 (PF00717, IPR019759): Peptidase S24-like
71 SFTPCprotein found in more fusions50.16724.885BRICHOS (PF04089, IPR007084, SM01039): BRICHOS domain
SP_C-Propep (PF08999, IPR015091): Surfactant protein C, N terminal propeptide
72 SLC6A8interactor201.618SNF (PF00209, IPR000175): Sodium:neurotransmitter symporter family
73 SLIRPinteractor30.6671.133RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
74 SPCS2interactor3051.298SPC25 (PF06703, IPR009582): Microsomal signal peptidase 25 kDa subunit (SPC25)
75 SPCS3interactor305.047SPC22 (PF04573, IPR007653): Signal peptidase subunit
76 SRPRAinteractor50.30024.292SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
SRP54 (PF00448, IPR000897, SM00962): SRP54-type protein, GTPase domain
SRP54_N (PF02881, IPR013822, SM00963): SRP54-type protein, helical bundle domain
77 SRPRBinteractor110.309117.386MHYT (PF03707, IPR005330): Bacterial signalling protein N terminal repeat
SRPRB (PF09439, IPR019009): Signal recognition particle receptor beta subunit
78 STK17Binteractor31.0000Pkinase (PF00069, IPR000719): Protein kinase domain
DUF2201_N (PF13203, IPR025154): Putative metallopeptidase domain
79 STT3Binteractor70.47640.081STT3 (PF02516, IPR003674): Oligosaccharyl transferase STT3 subunit
80 SUGP1interactor50.40010.952G-patch (PF01585, IPR000467, SM00443): G-patch domain
Herpes_DNAp_acc (PF04929, IPR007013): Herpes DNA replication accessory factor
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
OrfB_IS605 (PF01385, IPR001959): Probable transposase
RtcB (PF01139, IPR001233): tRNA-splicing ligase RtcB
Surp (PF01805, IPR000061, SM00648): Surp module
G-patch_2 (PF12656, IPR026822): G-patch domain
81 TECRinteractor90.38973.568Steroid_dh (PF02544, IPR001104): 3-oxo-5-alpha-steroid 4-dehydrogenase
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
82 TEPSINinteractor30.3332.850ENTH (PF01417, IPR001026, SM00273): ENTH domain
83 TIAL1interactor41.0000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
84 TM9SF4interactor2012.342EMP70 (PF02990, IPR004240): Endomembrane protein 70
DUF4229 (PF14012, IPR025323): Protein of unknown function (DUF4229)
85 TMEM17interactor280.032979.184Transmemb_17 (PF09799, IPR019184): Predicted membrane protein
DUF3043 (PF11241, IPR021403): Protein of unknown function (DUF3043)
86 TMEM199interactor30.6671.618Vma12 (PF11712, IPR021013): Endoplasmic reticulum-based factor for assembly of V-ATPase
87 TMEM63Binteractor60.13326.217RSN1_7TM (PF02714, IPR003864): Calcium-dependent channel, 7TM region, putative phosphate
Wzy_C (PF04932, IPR007016): O-Antigen ligase
DUF4006 (PF13179, IPR025065): Family of unknown function (DUF4006)
RSN1_TM (PF13967, IPR032880): Late exocytosis, associated with Golgi transport
PHM7_cyt (PF14703, IPR027815): Cytosolic domain of 10TM putative phosphate transporter
88 TOR1AIP1interactor50.10017.752LAP1C (PF05609, IPR008662): Lamina-associated polypeptide 1C (LAP1C)
Pap_E4 (PF02711, IPR003861): E4 protein
89 TOX3interactor100Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
PRP1_N (PF06424, IPR010491): PRP1 splicing factor, N-terminal
UPF0258 (PF06789, IPR009626): Uncharacterised protein family (UPF0258)
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
Hydin_ADK (PF17213): Hydin Adenylate kinase-like domain
90 TPX2interactor41.0000Aurora-A_bind (PF09041, IPR015128): Aurora-A binding
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
DUF2259 (PF10016, IPR018725): Predicted secreted protein (DUF2259)
TPX2_importin (PF12214, IPR027330): Cell cycle regulated microtubule associated protein
zf-TFIIIC (PF12660, IPR024764): Putative zinc-finger of transcription factor IIIC complex
DUF4337 (PF14235, IPR025570): Domain of unknown function (DUF4337)
91 TSG101suppressor60.7007.442APG6 (PF04111, IPR007243): Autophagy protein Apg6
Laminin_II (PF06009, IPR010307): Laminin Domain II
UEV (PF05743, IPR008883): UEV domain
Vps23_core (PF09454, IPR017916): Vps23 core domain
92 UBXN4interactor201.618Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region
Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like
UBX (PF00789, IPR001012, SM00166): UBX domain
Thioredoxin_7 (PF13899): Thioredoxin-like
93 UNC93B1interactor50.20040.785UNC-93 (PF05978, IPR010291): Ion channel regulatory protein UNC-93
Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup
DUF4131 (PF13567, IPR025405): Domain of unknown function (DUF4131)
94 VMA21interactor30.6671.618VMA21 (PF09446, IPR019013): VMA21-like domain
95 VRK2interactor3014.985Pkinase (PF00069, IPR000719): Protein kinase domain
VP_N-CPKC (PF11475, IPR021573): Virion protein N terminal domain
96 WWP2interactor50.16739.774WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
97 XRCC3oncoprotein40.33312.891Rad51 (PF08423, IPR013632): Rad51
RNA_pol_A_CTD (PF03118, IPR011260): Bacterial RNA polymerase, alpha chain C terminal domain
98 YAP1suppressor31.0000Bindin (PF02084, IPR000775): Bindin
WW (PF00397, IPR001202, SM00456): WW domain
GspL_C (PF12693, IPR025691): GspL periplasmic domain
FAM181 (PF15238, IPR029359): FAM181

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