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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins SEC11C, CDCP1 (from a repository: Sun Sep 23 09:45:56 2018)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)9
The number (and %) of the onco-proteins0 (0.00 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)10 (27.78 %)
The number (and %) of affected PPIs7 (70.00 %)
The number of possible different fusions1
PPI diameter2
PPI radiusinf
The average degree of PPI2.000
Assortativity coefficient0.2000
The network average Clustering coefficient0.481
The number (and %) of a zero Clustering coefficients4 (44.44 %)
The number (and %) of a zero Betweenness Centrality7 (77.78 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: CDCP1,SEC11C All fusions
Proteins found in more fusions

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 CDCP1parental protein306.000CUB (PF00431, IPR000859, SM00042): CUB domain
2 SEC11Cparental protein40.3338.000Peptidase_S24 (PF00717, IPR019759): Peptidase S24-like
3 ALBinteractor100Serum_albumin (PF00273, IPR014760, SM00103): Serum albumin family
4 CLK1interactor200PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region
Pkinase (PF00069, IPR000719): Protein kinase domain
5 HTR3Cinteractor21.0000Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
6 SDCBPinteractor100PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
7 SPCS2interactor21.0000SPC25 (PF06703, IPR009582): Microsomal signal peptidase 25 kDa subunit (SPC25)
8 TCTN2interactor21.0000DUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619)
9 TMEM30Ainteractor21.0000CDC50 (PF03381, IPR005045): LEM3 (ligand-effect modulator 3) family / CDC50 family

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