Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins GPRC5A, MARK2 (from a repository: Sat Sep 29 02:14:17 2018)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)104
The number (and %) of the onco-proteins28 (26.92 %)
The number (and %) of the tumor suppressors16 (15.38 %)
Total number of binary PPIs (saturation %)520 (9.71 %)
The number (and %) of affected PPIs104 (20.00 %)
The number of possible different fusions23
PPI diameter3
PPI radius2
The average degree of PPI9.308
Assortativity coefficient-0.2350
The network average Clustering coefficient0.463
The number (and %) of a zero Clustering coefficients14 (13.46 %)
The number (and %) of a zero Betweenness Centrality25 (24.04 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: MARK2,GPRC5A All fusions
Proteins found in more fusions AP2M1 (see 3 fusions); YWHAG (see 1 fusions); VCP (see 4 fusions); GAB2 (see 3 fusions); PKD1 (see 1 fusions); MARK2/RNF41 (see 1 fusions); SFN (see 1 fusions); HDAC7 (see 1 fusions); MARK2 (see 2 fusions); PINK1 (see 3 fusions); YWHAH (see 2 fusions); MAPT (see 1 fusions); UTRN (see 4 fusions); NEDD4L (see 3 fusions); YWHAZ (see 1 fusions); APC (see 1 fusions); MARK3 (see 1 fusions); RAB11FIP2 (see 1 fusions); PPP2R5E (see 1 fusions); PRKCE (see 3 fusions); NEDD4 (see 1 fusions); YWHAZ/PARD3 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 MARK2parental protein870.0776457.091DUF702 (PF05142, IPR007818): Domain of unknown function (DUF702)
KA1 (PF02149, IPR001772): Kinase associated domain 1
Pkinase (PF00069, IPR000719): Protein kinase domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
2 GPRC5Aparental protein170.176247.8387tm_3 (PF00003, IPR017978): 7 transmembrane sweet-taste receptor of 3 GCPR
3 ACTR2interactor110.58236.648Actin (PF00022, IPR004000, SM00268): Actin
4 AKT1oncoprotein190.222136.396PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
5 AP2M1protein found in more fusions120.364117.418Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family
Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain
6 APCsuppressor80.42925.882APC_15aa (PF05972, IPR009240): APC 15 residue motif
APC_basic (PF05956, IPR009234): APC basic domain
APC_r (PF05923): APC repeat
Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
EB1_binding (PF05937, IPR009232): EB-1 Binding Domain
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
SAMP (PF05924, IPR009224): SAMP Motif
Suppressor_APC (PF11414, IPR026831): Adenomatous polyposis coli tumour suppressor protein
AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term
SAS4 (PF15460, IPR029184): Something about silencing, SAS, complex subunit 4
Arm_APC_u3 (PF16629): Armadillo-associated region on APC
APC_u5 (PF16630): Unstructured region on APC between 1st and 2nd catenin-bdg motifs
APC_u9 (PF16633): Unstructured region on APC between 1st two creatine-rich regions
APC_u13 (PF16634): Unstructured region on APC between APC_crr and SAMP
APC_u14 (PF16635): Unstructured region on APC between SAMP and APC_crr
APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6
APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
7 ARHGEF2oncoprotein150.48646.733IncA (PF04156, IPR007285): IncA protein
PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
8 ATP6AP2interactor70.26721.026Phosphodiest (PF01663, IPR002591): Type I phosphodiesterase / nucleotide pyrophosphatase
Renin_r (PF07850, IPR012493): Renin receptor-like protein
9 AURKBinteractor100.36122.842Pkinase (PF00069, IPR000719): Protein kinase domain
10 BAIAP2interactor80.5719.963IMD (PF08397, IPR013606): IRSp53/MIM homology domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
11 C11orf58interactor100DUF3408 (PF11888, IPR021823): Protein of unknown function (DUF3408)
SMAP (PF15477, IPR028124): Small acidic protein family
12 CAMK1interactor100Pkinase (PF00069, IPR000719): Protein kinase domain
Tyrosinase (PF00264, IPR002227): Common central domain of tyrosinase
13 CAMSAP2interactor31.0000Bundlin (PF05307, IPR007971): Bundlin
IncA (PF04156, IPR007285): IncA protein
Presenilin (PF01080, IPR001108): Presenilin
CAMSAP_CKK (PF08683, IPR014797, SM01051): Microtubule-binding calmodulin-regulated spectrin-associated
CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain
FAM60A (PF15396, IPR026065): Protein Family FAM60A
CAMSAP_CC1 (PF17095, IPR031372): Spectrin-binding region of Ca2+-Calmodulin
14 CAPZA1interactor110.58255.535F-actin_cap_A (PF01267, IPR002189): F-actin capping protein alpha subunit
15 CAPZA2interactor130.51398.279F-actin_cap_A (PF01267, IPR002189): F-actin capping protein alpha subunit
16 CAPZBinteractor120.54571.236Cytochrom_B562 (PF07361, IPR009155): Cytochrome b562
F_actin_cap_B (PF01115, IPR001698): F-actin capping protein, beta subunit
17 CCDC8interactor240.233271.618Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA
18 CCDC82interactor100RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
DUF4196 (PF13846, IPR025244): Domain of unknown function (DUF4196)
DUF4211 (PF13926, IPR025451): Domain of unknown function (DUF4211)
19 CDC5Linteractor210.326167.210OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
20 CDK15interactor100Pkinase (PF00069, IPR000719): Protein kinase domain
ACT_5 (PF13710): ACT domain
21 CDKN1Asuppressor70.42918.115CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
22 CEP57interactor40.6676.657Cep57_MT_bd (PF06657, IPR024957): Centrosome microtubule-binding domain of Cep57
Tup_N (PF08581, IPR013890): Tup N-terminal
CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
TRIQK (PF15168, IPR024842): Triple QxxK/R motif-containing protein family
23 CEP85Linteractor100ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
Phage_GP20 (PF06810, IPR009636): Phage minor structural protein GP20
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
SlyX (PF04102, IPR007236): SlyX
Spc42p (PF11544, IPR021611): Spindle pole body component Spc42p
24 CEP89interactor50.40010.782ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CorA (PF01544, IPR002523): CorA-like Mg2+ transporter protein
Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit
Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain
Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
25 CLASP1interactor90.61113.290HEAT (PF02985, IPR000357): HEAT repeat
TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair
CTK3 (PF12243, IPR024638): CTD kinase subunit gamma CTK3
CLASP_N (PF12348, IPR024395): CLASP N terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Sec7_N (PF12783, IPR032691): Guanine nucleotide exchange factor in Golgi transport N-terminal
26 CLASP2interactor60.7331.602HEAT (PF02985, IPR000357): HEAT repeat
TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair
CLASP_N (PF12348, IPR024395): CLASP N terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Sec7_N (PF12783, IPR032691): Guanine nucleotide exchange factor in Golgi transport N-terminal
HEAT_EZ (PF13513): HEAT-like repeat
27 COL4A3BPinteractor31.0000Acyl_CoA_thio (PF02551, IPR025652): Acyl-CoA thioesterase
PH (PF00169, IPR001849, SM00233): PH domain
START (PF01852, IPR002913, SM00234): START domain
28 DBN1oncoprotein100.75610.043Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
29 DCTN1interactor130.30361.245Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like
CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain
FlgN (PF05130, IPR007809): FlgN protein
HOOK (PF05622, IPR008636): HOOK protein
SlyX (PF04102, IPR007236): SlyX
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
DUF2443 (PF10398, IPR019469): Protein of unknown function (DUF2443)
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
Dynactin (PF12455, IPR022157): Dynein associated protein
Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
KELK (PF15796, IPR031597): KELK-motif containing domain of MRCK Ser/Thr protein kinase
30 DLG5interactor30.6670.500Takusan (PF04822, IPR006907): Takusan
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
EMP24_GP25L (PF01105, IPR009038): emp24/gp25L/p24 family/GOLD
Occludin_ELL (PF07303, IPR010844): Occludin homology domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89
dbPDZ_assoc (PF16610): Unstructured region between two PDZ domains on Dlg5
31 DMDsuppressor40.5004.000CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
EF-hand_2 (PF09068, IPR015153): EF hand
EF-hand_3 (PF09069, IPR015154): EF-hand
FliD_N (PF02465, IPR003481): Flagellar hook-associated protein 2 N-terminus
IncA (PF04156, IPR007285): IncA protein
Spectrin (PF00435, IPR002017): Spectrin repeat
WW (PF00397, IPR001202, SM00456): WW domain
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
DinB_2 (PF12867, IPR024775): DinB superfamily
CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
32 DTNAinteractor30.6670.667ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CRISPR_Cse2 (PF09485, IPR013382): CRISPR-associated protein Cse2 (CRISPR_cse2)
EF-hand_2 (PF09068, IPR015153): EF hand
EF-hand_3 (PF09069, IPR015154): EF-hand
PMC2NT (PF08066, IPR012588): PMC2NT (NUC016) domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
33 EIF4A1interactor50.10011.259DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
34 FBXL16interactor21.0000LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
F-box-like (PF12937, IPR001810): F-box-like
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
35 FRYLoncoprotein41.0000MOR2-PAG1_N (PF14222, IPR025614): Cell morphogenesis N-terminal
MOR2-PAG1_C (PF14225, IPR025481): Cell morphogenesis C-terminal
MOR2-PAG1_mid (PF14228, IPR029473): Cell morphogenesis central region
PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain
36 FUCA1interactor21.0000Alpha_L_fucos (PF01120, IPR000933, SM00812): Alpha-L-fucosidase
Fucosidase_C (PF16757, IPR031919): Alpha-L-fucosidase C-terminal domain
37 GAB1oncoprotein60.4677.174PH (PF00169, IPR001849, SM00233): PH domain
38 GAB2oncoprotein60.7001.947PH (PF00169, IPR001849, SM00233): PH domain
Pheromone (PF08015, IPR012597): Fungal mating-type pheromone
39 GOLT1Binteractor30.33310.993Got1 (PF04178, IPR007305): Got1/Sft2-like family
40 GPRASP1interactor100Arm_2 (PF04826, IPR006911): Armadillo-like
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
41 GTF2F2interactor201.721TFIIF_beta (PF02270, IPR003196): Transcription initiation factor IIF, beta subunit
42 HDAC7protein found in more fusions100.9170.564Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
CBP_BcsO (PF17037, IPR031484): Cellulose biosynthesis protein BcsO
43 HERC2interactor50.8330.667ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cyt-b5 (PF00173, IPR001199, SM01117): Cytochrome b5-like Heme/Steroid binding domain
MIB_HERC2 (PF06701, IPR010606): Mib_herc2
RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
44 HNRNPA1interactor130.59122.770RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
45 HSPA9oncoprotein110.20062.785HSP70 (PF00012, IPR013126): Hsp70 protein
46 KIF13Binteractor40.6674.445CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain
DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342)
FHA (PF00498, IPR000253, SM00240): FHA domain
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
KIF1B (PF12423, IPR022140): Kinesin protein 1B
DUF3694 (PF12473, IPR022164): Kinesin protein
NCKAP5 (PF15246, IPR032769): Nck-associated protein 5, Peripheral clock protein
Kinesin_assoc (PF16183, IPR032405): Kinesin-associated
47 KIF5Binteractor120.66712.707ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Sec2p (PF06428, IPR009449): GDP/GTP exchange factor Sec2p
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
DUF3584 (PF12128, IPR021979): Protein of unknown function (DUF3584)
HAUS-augmin3 (PF14932, IPR032733): HAUS augmin-like complex subunit 3
DUF4226 (PF10774, IPR019710): Domain of unknown function (DUF4226)
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
48 LDHDinteractor21.0000FAD-oxidase_C (PF02913, IPR004113): FAD linked oxidases, C-terminal domain
FAD_binding_4 (PF01565, IPR006094): FAD binding domain
49 LIMA1suppressor170.404102.250LIM (PF00412, IPR001781, SM00132): LIM domain
ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain
50 MAP3K3oncoprotein70.4674.542PB1 (PF00564, IPR000270, SM00666): PB1 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
51 MAPTprotein found in more fusions110.44414.132Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat
52 MARK1interactor80.5005.538KA1 (PF02149, IPR001772): Kinase associated domain 1
Pkinase (PF00069, IPR000719): Protein kinase domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
53 MARK3protein found in more fusions200.35797.662KA1 (PF02149, IPR001772): Kinase associated domain 1
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
Pkinase (PF00069, IPR000719): Protein kinase domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
54 MARK4oncoprotein150.23875.149KA1 (PF02149, IPR001772): Kinase associated domain 1
Pkinase (PF00069, IPR000719): Protein kinase domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
55 MPV17interactor202.158Mpv17_PMP22 (PF04117, IPR007248): Mpv17 / PMP22 family
56 MTCL1interactor80.4298.917bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
SOGA (PF11365, IPR027881): Protein SOGA
DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
DUF4201 (PF13870, IPR025254): Domain of unknown function (DUF4201)
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
DUF4482 (PF14818, IPR027882): Domain of unknown function (DUF4482)
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
57 MYH9suppressor200.295174.900IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
58 MYO19interactor110.67316.470IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
59 NAP1L5interactor21.0000NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP)
SspB (PF04386, IPR007481): Stringent starvation protein B
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
60 NEDD4suppressor80.28617.914Rota_NS26 (PF01525, IPR002512): Rotavirus NS26
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
61 NEDD4Lsuppressor110.7116.706WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
62 NOLC1interactor60.66712.281DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
SRP40_C (PF05022, IPR007718): SRP40, C-terminal domain
Stm1_N (PF09598, IPR019084): Stm1
stn_TNFRSF12A (PF12191, IPR022316): Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain
NST1 (PF13945, IPR025279): Salt tolerance down-regulator
SEEEED (PF14797, IPR029394): Serine-rich region of AP3B1, clathrin-adaptor complex
DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611)
PAF (PF15715, IPR031444): PCNA-associated factor
IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
NuDC (PF16273, IPR032572): Nuclear distribution C domain
PHC2_SAM_assoc (PF16616): Unstructured region on Polyhomeotic-like protein 1 and 2
63 NTRK1oncoprotein380.216803.927I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
64 NUPL2interactor21.0000zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
65 PARD3protein found in more fusions120.53019.713PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DUF3534 (PF12053, IPR021922): Domain of unknown function (DUF3534)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
66 PARD6Ainteractor70.6676.696PB1 (PF00564, IPR000270, SM00666): PB1 domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
67 PARD6Ginteractor51.0000PB1 (PF00564, IPR000270, SM00666): PB1 domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
68 PDCD7interactor100PDCD7 (PF16021, IPR031974): Programmed cell death protein 7
69 PHLPP1suppressor21.0000LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
PH (PF00169, IPR001849, SM00233): PH domain
PP2C (PF00481, IPR001932): Protein phosphatase 2C
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
PRIMA1 (PF16101): Proline-rich membrane anchor 1
70 PINK1protein found in more fusions31.0000Pkinase (PF00069, IPR000719): Protein kinase domain
71 PKD1suppressor200Stress-antifung (PF01657, IPR002902): Salt stress response/antifungal
LRRCT (PF01463, IPR000483, SM00082): Leucine rich repeat C-terminal domain
LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
PKD (PF00801, IPR000601, SM00089): PKD domain
PKD_channel (PF08016, IPR013122): Polycystin cation channel
PLAT (PF01477, IPR001024, SM00308): PLAT/LH2 domain
REJ (PF02010, IPR002859): REJ domain
WSC (PF01822, IPR002889, SM00321): WSC domain
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
fn3_3 (PF14686, IPR029413): Polysaccharide lyase family 4, domain II
72 PMPCAinteractor100Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
73 PPP2R1Aoncoprotein160.317128.699TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain
HEAT (PF02985, IPR000357): HEAT repeat
HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
74 PPP2R5Eprotein found in more fusions31.0000B56 (PF01603, IPR002554): Protein phosphatase 2A regulatory B subunit (B56 family)
75 PRDX3interactor31.0000AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
76 PRKAA1suppressor100.48919.048Pkinase (PF00069, IPR000719): Protein kinase domain
AdenylateSensor (PF16579, IPR032270): Adenylate sensor of SNF1-like protein kinase
77 PRKCEsuppressor40.6673.991C2 (PF00168, IPR000008, SM00239): C2 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
78 PRKCIinteractor110.50920.282PB1 (PF00564, IPR000270, SM00666): PB1 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
79 PTPAsuppressor70.33327.598PTPA (PF03095, IPR004327): Phosphotyrosyl phosphate activator (PTPA) protein
80 RAB11FIP2protein found in more fusions80.66750.632C2 (PF00168, IPR000008, SM00239): C2 domain
RBD-FIP (PF09457, IPR019018): FIP domain
81 RAB5Concoprotein60.33340.970Ras (PF00071, IPR001806, SM00173): Ras family
82 RAB7Asuppressor90.27842.093Ras (PF00071, IPR001806, SM00173): Ras family
83 RHOAsuppressor60.133180.362Ras (PF00071, IPR001806, SM00173): Ras family
84 RNF41protein found in more fusions70.4676.000Sina (PF03145, IPR018121): Seven in absentia protein family
USP8_interact (PF08941, IPR015036): USP8 interacting
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
85 RSF1oncoprotein100DDT (PF02791, IPR004022, SM00571): DDT domain
DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
PHD (PF00628, IPR019787, SM00249): PHD-finger
UPF0239 (PF06783, IPR009621): Uncharacterised protein family (UPF0239)
TFIIE-A_C (PF11521, IPR021600): C-terminal general transcription factor TFIIE alpha
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
WHIM1 (PF15612, IPR028942): WSTF, HB1, Itc1p, MBD9 motif 1
86 SFNsuppressor140.52619.83414-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
87 SLC25A3interactor70.42918.875Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
88 SNTB2interactor50.300116.249PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
PH (PF00169, IPR001849, SM00233): PH domain
89 SOGA1interactor80.42924.368ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
bZIP_1 (PF00170, IPR004827): bZIP transcription factor
CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
SPT16 (PF08644, IPR013953): FACT complex subunit (SPT16/CDC68)
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
SOGA (PF11365, IPR027881): Protein SOGA
Dscam_C (PF12355, IPR021012): Down syndrome cell adhesion molecule C terminal
DUF4482 (PF14818, IPR027882): Domain of unknown function (DUF4482)
90 STK11suppressor40.6671.820Pkinase (PF00069, IPR000719): Protein kinase domain
91 SYNPOinteractor120.50044.148Calsarcin (PF05556, IPR008438): Calcineurin-binding protein (Calsarcin)
92 TADA2Ainteractor40.5001.971SWIRM (PF04433, IPR007526): SWIRM domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
93 TMEM17interactor90.333160.639Transmemb_17 (PF09799, IPR019184): Predicted membrane protein
DUF3043 (PF11241, IPR021403): Protein of unknown function (DUF3043)
94 USP21interactor90.32113.095UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
95 UTP18interactor100Cytochrom_D1 (PF02239): Cytochrome D1 heme domain
SAMP (PF05924, IPR009224): SAMP Motif
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
96 UTRNprotein found in more fusions70.33317.030bZIP_1 (PF00170, IPR004827): bZIP transcription factor
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
EF-hand_2 (PF09068, IPR015153): EF hand
EF-hand_3 (PF09069, IPR015154): EF-hand
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Spectrin (PF00435, IPR002017): Spectrin repeat
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
WW (PF00397, IPR001202, SM00456): WW domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
ABC_tran_CTD (PF16326, IPR032524): ABC transporter C-terminal domain
97 VCPprotein found in more fusions190.49096.233AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
98 WDR46interactor100BING4CT (PF08149, IPR012952, SM01033): BING4CT (NUC141) domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
99 YWHABinteractor240.373120.60114-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
Virulence_fact (PF13769, IPR025989): Virulence factor
100 YWHAEoncoprotein280.325214.57914-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
101 YWHAGprotein found in more fusions280.356206.71214-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
102 YWHAHprotein found in more fusions240.403107.60514-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
103 YWHAQinteractor230.451107.71814-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
104 YWHAZprotein found in more fusions290.354214.24714-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein

B a c k    t o    T o p ⇑