Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins RASA1, CCNH (from a repository: Tue Aug 20 12:33:48 2019)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)104
The number (and %) of the onco-proteins47 (45.19 %)
The number (and %) of the tumor suppressors20 (19.23 %)
Total number of binary PPIs (saturation %)622 (11.61 %)
The number (and %) of affected PPIs102 (16.40 %)
The number of possible different fusions26
PPI diameter5
PPI radius3
The average degree of PPI11.038
Assortativity coefficient-0.2513
The network average Clustering coefficient0.450
The number (and %) of a zero Clustering coefficients9 (8.65 %)
The number (and %) of a zero Betweenness Centrality14 (13.46 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: RASA1,CCNH All fusions
Proteins found in more fusions PTBP1 (see 1 fusions); APP (see 5 fusions); MCM7 (see 2 fusions); G3BP1 (see 1 fusions); SFN (see 1 fusions); GRB2 (see 1 fusions); LCK (see 1 fusions); CTBP2 (see 2 fusions); PTK2B (see 1 fusions); MYC (see 2 fusions); PPFIA1 (see 2 fusions); SSX2IP (see 1 fusions); ERBB3 (see 2 fusions); KHDRBS1 (see 1 fusions); NDC80 (see 1 fusions); EGFR (see 2 fusions); RACK1 (see 3 fusions); EPHB2 (see 1 fusions); HTT (see 1 fusions); POLR2A (see 2 fusions); EZH2 (see 1 fusions); RPA1 (see 1 fusions); NEDD4 (see 1 fusions); TP53 (see 3 fusions); CDK9 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 RASA1parental protein510.1382160.192C2 (PF00168, IPR000008, SM00239): C2 domain
PH (PF00169, IPR001849, SM00233): PH domain
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
2 CCNHparental protein510.1431996.6705_3_exonuc_N (PF02739, IPR020046): 5'-3' exonuclease, N-terminal resolvase-like domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
Cyclin_C_2 (PF16899, IPR031658): Cyclin C-terminal domain
3 ABL1oncoprotein250.322259.572Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2
4 ANXA6interactor30.6671.383Annexin (PF00191, IPR018502, SM00335): Annexin
5 APPprotein found in more fusions190.150458.442APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
6 ARoncoprotein150.396139.993Androgen_recep (PF02166, IPR001103): Androgen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
7 ARHGAP35oncoprotein31.0000FF (PF01846, IPR002713, SM00441): FF domain
Ras (PF00071, IPR001806, SM00173): Ras family
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
RhoGAP-FF1 (PF16512, IPR032835): p190-A and -B Rho GAPs FF domain
8 BBS10interactor100Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
9 BRCA1suppressor250.304308.666BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
10 BTRConcoprotein110.24473.999WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
11 CALCOCO2interactor80.3819.079bZIP_1 (PF00170, IPR004827): bZIP transcription factor
CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like
DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641)
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
zf-C2H2_4 (PF13894): C2H2-type zinc finger
12 CAV2interactor40.8330.297Caveolin (PF01146, IPR001612): Caveolin
13 CCDC170interactor100LigT_PEase (PF02834, IPR014051): LigT like Phosphoesterase
Med9 (PF07544, IPR011425): RNA polymerase II transcription mediator complex subunit 9
DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1
DUF745 (PF05335, IPR007999): Protein of unknown function (DUF745)
HAP1_N (PF04849, IPR006933): HAP1 N-terminal conserved region
Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain
NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
Sec2p (PF06428, IPR009449): GDP/GTP exchange factor Sec2p
Tropomyosin (PF00261, IPR000533): Tropomyosin
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89
DUF4473 (PF14747, IPR027913): Domain of unknown function (DUF4473)
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
14 CCDC33interactor50.30018.189C2 (PF00168, IPR000008, SM00239): C2 domain
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
SlyX (PF04102, IPR007236): SlyX
15 CCNCsuppressor50.8000.857Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
Cyclin_C_2 (PF16899, IPR031658): Cyclin C-terminal domain
16 CD5interactor31.0000SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain
Comm (PF15957, IPR031878): Commissureless
17 CDK2suppressor220.376132.342Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
18 CDK20oncoprotein50.6001.508Pkinase (PF00069, IPR000719): Protein kinase domain
19 CDK7oncoprotein280.345249.933Pkinase (PF00069, IPR000719): Protein kinase domain
20 CDK8interactor100.69410.830Pkinase (PF00069, IPR000719): Protein kinase domain
21 CDK9protein found in more fusions100.6944.402Pkinase (PF00069, IPR000719): Protein kinase domain
22 CPSF4Linteractor100zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
zf-CCCH_3 (PF15663): Zinc-finger containing family
Torus (PF16131, IPR032297): Torus domain
23 CSKinteractor110.49114.478Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
24 CSNK2Binteractor130.318104.064CK_II_beta (PF01214, IPR000704, SM01085): Casein kinase II regulatory subunit
25 CTBP2protein found in more fusions50.16712.3282-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
26 DNAJA3suppressor70.28637.943DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
27 DOK1suppressor130.57616.520IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
PH (PF00169, IPR001849, SM00233): PH domain
28 DOK2suppressor70.52478.324IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
PH (PF00169, IPR001849, SM00233): PH domain
29 DUSP12interactor30.3337.693DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
Yippee-Mis18 (PF03226, IPR004910): Yippee zinc-binding/DNA-binding /Mis18, centromere assembly
30 EGFRoncoprotein360.225729.421Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
31 EIF1interactor21.0000SUI1 (PF01253, IPR001950): Translation initiation factor SUI1
32 EPHB2suppressor60.7000.971EGF_2 (PF07974, IPR013111): EGF-like domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
33 EPHB3suppressor100fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
34 ERBB2oncoprotein150.50542.930Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
35 ERBB3oncoprotein140.53842.935Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
36 ERBB4suppressor90.64314.089Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
DUF3951 (PF13131, IPR025028): Protein of unknown function (DUF3951)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
37 ERCC2oncoprotein110.67358.738DEAD_2 (PF06733, IPR010614): DEAD_2
HBB (PF06777, IPR010643): Helical and beta-bridge domain
ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit
Helicase_C_2 (PF13307, IPR006555): Helicase C-terminal domain
TIR_2 (PF13676, IPR000157): TIR domain
SesA (PF17107, IPR031352): N-terminal domain on NACHT_NTPase and P-loop NTPases
38 ERCC3oncoprotein160.51752.402ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit
DUF2748 (PF10871, IPR020183): Protein of unknown function (DUF2748)
Helicase_C_3 (PF13625, IPR032830): Helicase conserved C-terminal domain
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
ERCC3_RAD25_C (PF16203, IPR032438): ERCC3/RAD25/XPB C-terminal helicase
39 ERCC5oncoprotein70.9051.4995_3_exonuc (PF01367, IPR020045, SM00475): 5'-3' exonuclease, C-terminal SAM fold
XPG_I (PF00867, IPR006086, SM00484): XPG I-region
XPG_N (PF00752, IPR006085, SM00485): XPG N-terminal domain
IZUMO (PF15005, IPR029389): Izumo sperm-egg fusion, Ig domain-associated
Codanin-1_C (PF15296, IPR028171): Codanin-1 C-terminus
EF-G-binding_N (PF07299): Elongation factor G-binding protein, N-terminal
40 ESR1suppressor280.251412.158Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
41 EZH2suppressor100.38938.594CDC45 (PF02724, IPR003874): CDC45-like protein
TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain
SET (PF00856, IPR001214, SM00317): SET domain
EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
42 FUBP1oncoprotein70.61910.151DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897)
KH_1 (PF00013, IPR004088, SM00322): KH domain
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
43 G3BP1protein found in more fusions100.27856.248NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
44 GANABsuppressor60.7334.449Glyco_hydro_31 (PF01055, IPR000322): Glycosyl hydrolases family 31
Gal_mutarotas_2 (PF13802, IPR025887): Galactose mutarotase-like
DUF5110 (PF17137): Domain of unknown function (DUF5110)
45 GOLGA2interactor80.46420.935ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
GOLGA2L5 (PF15070, IPR024858): Putative golgin subfamily A member 2-like protein 5
46 GRB2oncoprotein270.302340.085SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
47 GTF2H1oncoprotein160.56739.419BSD (PF03909, IPR005607, SM00751): BSD domain
PH_TFIIH (PF08567, IPR013876): TFIIH p62 subunit, N-terminal domain
48 GTF2H2interactor90.8891.866C1_4 (PF07975, IPR004595, SM01047): TFIIH C1-like domain
Prim_Zn_Ribbon (PF08273, IPR013237, SM00778): Zinc-binding domain of primase-helicase
Ssl1 (PF04056, IPR007198): Ssl1-like
zf-HIT (PF04438, IPR007529): HIT zinc finger
UPF0547 (PF10571, IPR018886): Uncharacterised protein family UPF0547
zf-C2H2_4 (PF13894): C2H2-type zinc finger
49 GTF2H4interactor110.74518.028Tfb2 (PF03849, IPR004598): Transcription factor Tfb2
50 GTF2H5interactor90.8891.202Tfb5 (PF06331, IPR009400): Transcription factor TFIIH complex subunit Tfb5
51 HCKoncoprotein100.44439.894Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
52 HNRNPFinteractor130.43676.215RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Spot_14 (PF07084, IPR009786): Thyroid hormone-inducible hepatic protein Spot 14
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
53 HRASoncoprotein40.5009.851Ras (PF00071, IPR001806, SM00173): Ras family
54 HTTprotein found in more fusions60.6005.639HEAT (PF02985, IPR000357): HEAT repeat
SPX (PF03105, IPR004331): SPX domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
DUF3652 (PF12372, IPR024613): Huntingtin protein region
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
55 IGF1Roncoprotein130.34682.576fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
56 INSRinteractor100.44427.224fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
57 KDRoncoprotein50.7002.782Ehrlichia_rpt (PF09528, IPR019048): Ehrlichia tandem repeat (Ehrlichia_rpt)
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
58 KHDRBS1protein found in more fusions170.258133.695KH_1 (PF00013, IPR004088, SM00322): KH domain
Qua1 (PF16274, IPR032571): Qua1 domain
Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68
59 KLC3interactor31.0000TPR_4 (PF07721, IPR011717): Tetratricopeptide repeat
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
TPR_12 (PF13424): Tetratricopeptide repeat
60 LCKoncoprotein130.197116.034Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
61 MAP4K4interactor40.33310.816CNH (PF00780, IPR001180, SM00036): CNH domain
FUSC (PF04632, IPR006726): Fusaric acid resistance protein family
Pkinase (PF00069, IPR000719): Protein kinase domain
FAM165 (PF14981, IPR028023): FAM165 family
SOBP (PF15279, IPR026092): Sine oculis-binding protein
FAM60A (PF15396, IPR026065): Protein Family FAM60A
62 MCM7protein found in more fusions110.60020.903MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
63 MNAT1oncoprotein190.49154.479MAT1 (PF06391, IPR015877): CDK-activating kinase assembly factor MAT1
Mu-like_Com (PF10122, IPR019294): Mu-like prophage protein Com
zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger)
64 MTA1oncoprotein60.6674.836BAH (PF01426, IPR001025, SM00439): BAH domain
ELM2 (PF01448, IPR000949): ELM2 domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
GATA (PF00320, IPR000679, SM00401): GATA zinc finger
65 MYConcoprotein230.277281.263HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
66 NCK1oncoprotein150.36249.288SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
67 NDC80protein found in more fusions50.33338.952DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region
Ndc80_HEC (PF03801, IPR005550): HEC/Ndc80p family
SlyX (PF04102, IPR007236): SlyX
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
68 NEDD4suppressor140.308130.857Rota_NS26 (PF01525, IPR002512): Rotavirus NS26
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
69 NFKBIAoncoprotein110.27372.612Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
70 NTRK1oncoprotein380.1411246.233I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
71 OLIG1interactor50.5002.227HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446)
Metal_resist (PF13801, IPR025961): Heavy-metal resistance
72 PDGFRBoncoprotein90.7507.009I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
Ig_3 (PF13927): Immunoglobulin domain
TonB_N (PF16031): TonB N-terminal region
73 PLCG1oncoprotein160.50050.832C2 (PF00168, IPR000008, SM00239): C2 domain
PH (PF00169, IPR001849, SM00233): PH domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
PI-PLC-X (PF00388, IPR000909, SM00148): Phosphatidylinositol-specific phospholipase C, X domain
PI-PLC-Y (PF00387, IPR001711, SM00149): Phosphatidylinositol-specific phospholipase C, Y domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
PH_12 (PF16457, IPR001849): Pleckstrin homology domain
74 POLR2Aprotein found in more fusions230.372264.310RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1
RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2
RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3
RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4
RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5
RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
75 POLR2Binteractor100.53351.972RNA_pol_Rpb2_1 (PF04563, IPR007644): RNA polymerase beta subunit
RNA_pol_Rpb2_3 (PF04565, IPR007645): RNA polymerase Rpb2, domain 3
RNA_pol_Rpb2_4 (PF04566, IPR007646): RNA polymerase Rpb2, domain 4
RNA_pol_Rpb2_5 (PF04567, IPR007647): RNA polymerase Rpb2, domain 5
RNA_pol_Rpb2_6 (PF00562, IPR007120): RNA polymerase Rpb2, domain 6
RNA_pol_Rpb2_7 (PF04560, IPR007641): RNA polymerase Rpb2, domain 7
76 PPFIA1protein found in more fusions40.3332.621HWE_HK (PF07536, IPR011102, SM00911): HWE histidine kinase
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2
Cluap1 (PF10234, IPR019366): Clusterin-associated protein-1
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
TSNAXIP1_N (PF15739, IPR032755): Translin-associated factor X-interacting N-terminus
FAM76 (PF16046, IPR032017): FAM76 protein
CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour
77 PSMA1interactor90.25052.967Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
78 PTBP1oncoprotein100.41737.782RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
79 PTK2Bprotein found in more fusions90.6436.021FERM_M (PF00373, IPR019748): FERM central domain
Focal_AT (PF03623, IPR005189): Focal adhesion targeting region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
80 PXNoncoprotein80.5365.866LIM (PF00412, IPR001781, SM00132): LIM domain
Paxillin (PF03535): Paxillin family
81 RACK1suppressor130.39465.950WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
82 RADILinteractor30.33315.792DIL (PF01843, IPR018444, SM01132): DIL domain
FHA (PF00498, IPR000253, SM00240): FHA domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
83 RARBsuppressor100zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
84 RPA1suppressor200.43990.742Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
85 RPA2oncoprotein140.45195.290RPA_C (PF08784, IPR014892): Replication protein A C terminal
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
86 RPA3interactor110.51128.335Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
87 SERPINA4interactor100Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
88 SFNsuppressor90.50025.69614-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
89 SLC9A2oncoprotein31.0000Na_H_Exchanger (PF00999, IPR006153): Sodium/hydrogen exchanger family
Sigma_reg_N (PF13800, IPR029101): Sigma factor regulator N-terminal
NEXCaM_BD (PF16644, IPR032103): Regulatory region of Na+/H+ exchanger NHE binds to calmodulin
90 SOCS1suppressor100.51123.566SH2 (PF00017, IPR000980, SM00252): SH2 domain
SOCS_box (PF07525, IPR001496): SOCS box
91 SOCS3suppressor100.40022.225SH2 (PF00017, IPR000980, SM00252): SH2 domain
SOCS_box (PF07525, IPR001496): SOCS box
92 SPSB1interactor204.154SPRY (PF00622, IPR003877, SM00449): SPRY domain
SOCS_box (PF07525, IPR001496): SOCS box
93 SRConcoprotein280.285476.464Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
94 SSSCA1interactor40.33331.543Auto_anti-p27 (PF06677, IPR009563): Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27)
95 SSX2IPprotein found in more fusions70.40020.475ZapB (PF06005, IPR009252): Cell division protein ZapB
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Surfac_D-trimer (PF09006, IPR015097): Lung surfactant protein D coiled-coil trimerisation
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
YqzH (PF14164, IPR025546): YqzH-like protein
96 SUPT5Hinteractor110.50919.071KOW (PF00467, IPR005824, SM00739): KOW motif
Ribonuc_P_40 (PF08584, IPR013893): Ribonuclease P 40kDa (Rpp40) subunit
Spt5-NGN (PF03439, IPR005100): Early transcription elongation factor of RNA pol II, NGN section
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
DUF3912 (PF13051, IPR025023): Protein of unknown function (DUF3912)
97 TBC1D15interactor202.135Cortex-I_coil (PF09304, IPR015383): Cortexillin I, coiled coil
RabGAP-TBC (PF00566, IPR000195, SM00164): Rab-GTPase-TBC domain
DUF3548 (PF12068, IPR021935): Domain of unknown function (DUF3548)
98 TP53suppressor360.213892.747DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
99 TRIM8interactor31.0000dCache_2 (PF08269, IPR004010, SM01049): Cache domain
CASP_C (PF08172, IPR012955): CASP C terminal
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
Zn_ribbon_recom (PF13408, IPR025827): Recombinase zinc beta ribbon domain
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
100 TRMT2Ainteractor31.0000PCMT (PF01135, IPR000682): Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
tRNA_U5-meth_tr (PF05958, IPR010280): tRNA (Uracil-5-)-methyltransferase
Methyltransf_31 (PF13847, IPR025714): Methyltransferase domain
Hepar_II_III_N (PF16889, IPR031680): Heparinase II/III N-terminus
101 XRCC6oncoprotein170.292143.092Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
SAP (PF02037, IPR003034, SM00513): SAP domain
102 YES1oncoprotein100.24451.067Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
YdjC (PF04794, IPR006879): YdjC-like protein
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
103 ZAP70interactor110.53332.074Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
104 ZNF579interactor100SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
Anti-TRAP (PF15777, IPR031538): Tryptophan RNA-binding attenuator protein inhibitory protein
PRIMA1 (PF16101): Proline-rich membrane anchor 1
zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger

B a c k    t o    T o p ⇑