1 |
EBAG9 | parental protein | 3 | 0 | 9.317 | DUF3395 (PF11875, IPR024586): Domain of unknown function (DUF3395) |
2 |
CASK | parental protein | 62 | 0.043 | 3484.195 | L27 (PF02828, IPR014775, SM00569): L27 domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) Pkinase (PF00069, IPR000719): Protein kinase domain SH3_2 (PF07653, IPR011511): Variant SH3 domain Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase |
3 |
ABLIM1 | interactor | 4 | 0.667 | 1.667 | LIM (PF00412, IPR001781, SM00132): LIM domain VHP (PF02209, IPR003128, SM00153): Villin headpiece domain zf-dskA_traR (PF01258, IPR000962): Prokaryotic dksA/traR C4-type zinc finger DUF2175 (PF09943, IPR018686): Uncharacterized protein conserved in archaea (DUF2175) AbLIM_anchor (PF16182, IPR032402): Putative adherens-junction anchoring region of AbLIM |
4 |
APBA1 | interactor | 6 | 0.667 | 4.400 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) |
5 |
ARHGEF26 | interactor | 2 | 1.000 | 0 | PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_9 (PF14604, IPR001452): Variant SH3 domain |
6 |
ARIH1 | protein found in more fusions | 3 | 1.000 | 0 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain Med14 (PF08638, IPR013947): Mediator complex subunit MED14 zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain |
7 |
ATP2B4 | interactor | 4 | 0.833 | 0.667 | Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Hydrolase (PF00702, IPR023214): haloacid dehalogenase-like hydrolase Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase ATP_Ca_trans_C (PF12424, IPR022141): Plasma membrane calcium transporter ATPase C terminal Cation_ATPase (PF13246): Cation transport ATPase (P-type) |
8 |
BNIP3L | suppressor | 3 | 1.000 | 0 | BNIP3 (PF06553, IPR010548): BNIP3 |
9 |
CDK9 | protein found in more fusions | 6 | 0.500 | 5.500 | Pkinase (PF00069, IPR000719): Protein kinase domain |
10 |
CEP128 | interactor | 7 | 0.333 | 13.667 | DUF1129 (PF06570, IPR009214): Protein of unknown function (DUF1129) DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein SpoOE-like (PF09388, IPR018540): Spo0E like sporulation regulatory protein DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968) TraF_2 (PF13729, IPR032811): F plasmid transfer operon, TraF, protein GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) HAUS6_N (PF14661, IPR028163): HAUS augmin-like complex subunit 6 N-terminus HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
11 |
CNTNAP2 | suppressor | 1 | 0 | 0 | COLFI (PF01410, IPR000885, SM00038): Fibrillar collagen C-terminal domain EGF (PF00008, IPR000742, SM00181): EGF-like domain Laminin_G_2 (PF02210, IPR001791): Laminin G domain SCRL (PF06876, IPR010682): Plant self-incompatibility response (SCRL) protein Syndecan (PF01034, IPR027789): Syndecan domain F5_F8_type_C (PF00754, IPR000421, SM00231): F5/8 type C domain hEGF (PF12661, IPR013032): Human growth factor-like EGF |
12 |
CNTNAP4 | interactor | 2 | 1.000 | 0 | COLFI (PF01410, IPR000885, SM00038): Fibrillar collagen C-terminal domain EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_2 (PF07974, IPR013111): EGF-like domain Laminin_G_2 (PF02210, IPR001791): Laminin G domain F5_F8_type_C (PF00754, IPR000421, SM00231): F5/8 type C domain MAP17 (PF15807, IPR031627): Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 |
13 |
DLG1 | suppressor | 12 | 0.333 | 43.976 | L27_1 (PF09058, IPR015143): L27_1 PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) SH3_2 (PF07653, IPR011511): Variant SH3 domain KOG2701 (PF09762, IPR019159): Coiled-coil domain-containing protein (DUF2037) MAGUK_N_PEST (PF10608, IPR019590): Polyubiquitination (PEST) N-terminal domain of MAGUK PDZ_assoc (PF10600, IPR019583): PDZ-associated domain of NMDA receptors Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase |
14 |
DLG4 | protein found in more fusions | 9 | 0.429 | 15.602 | L27_1 (PF09058, IPR015143): L27_1 PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) MAGUK_N_PEST (PF10608, IPR019590): Polyubiquitination (PEST) N-terminal domain of MAGUK PDZ_assoc (PF10600, IPR019583): PDZ-associated domain of NMDA receptors Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
15 |
DTNB | interactor | 3 | 1.000 | 0 | EF-hand_2 (PF09068, IPR015153): EF hand EF-hand_3 (PF09069, IPR015154): EF-hand Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain Ax_dynein_light (PF10211, IPR019347): Axonemal dynein light chain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type SOGA (PF11365, IPR027881): Protein SOGA |
16 |
DUSP3 | interactor | 3 | 0.667 | 1.667 | DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain |
17 |
EEF2 | interactor | 2 | 1.000 | 0 | EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II |
18 |
ELAVL1 | oncoprotein | 18 | 0.147 | 193.702 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
19 |
ELL2 | interactor | 2 | 1.000 | 0 | Occludin_ELL (PF07303, IPR010844): Occludin homology domain Wbp11 (PF09429, IPR019007): WW domain binding protein 11 ELL (PF10390, IPR019464): RNA polymerase II elongation factor ELL |
20 |
EPB41 | suppressor | 3 | 1.000 | 0 | 4_1_CTD (PF05902, IPR008379): 4.1 protein C-terminal domain (CTD) FA (PF08736, IPR014847): FERM adjacent (FA) FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain SAB (PF04382, IPR007477): SAB domain |
21 |
ERBIN | oncoprotein | 4 | 1.000 | 0 | LRR_1 (PF00560, IPR001611): Leucine Rich Repeat Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat |
22 |
F11R | interactor | 3 | 0.667 | 34.967 | FixS (PF03597, IPR004714): Cytochrome oxidase maturation protein cbb3-type Ig_3 (PF13927): Immunoglobulin domain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
23 |
FCHSD2 | protein found in more fusions | 3 | 1.000 | 0 | Cortex-I_coil (PF09304, IPR015383): Cortexillin I, coiled coil DivIC (PF04977, IPR007060): Septum formation initiator FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain DUF4665 (PF15679, IPR031389): Domain of unknown function (DUF4665) Rit1_C (PF17184): Rit1 N-terminal domain |
24 |
FOXRED2 | interactor | 2 | 1.000 | 0 | Pyr_redox_3 (PF13738): Pyridine nucleotide-disulphide oxidoreductase |
25 |
GCNT3 | oncoprotein | 1 | 0 | 0 | Branch (PF02485, IPR003406): Core-2/I-Branching enzyme |
26 |
HGS | interactor | 5 | 0.400 | 27.176 | FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif VHS (PF00790, IPR002014, SM00288): VHS domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate PIEZO (PF15917, IPR031805): Piezo |
27 |
ID1 | interactor | 1 | 0 | 0 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
28 |
IL15RA | interactor | 1 | 0 | 0 | NA |
29 |
IL18 | interactor | 1 | 0 | 0 | IL1 (PF00340, IPR000975, SM00125): Interleukin-1 / 18 |
30 |
KCNJ12 | interactor | 9 | 0.500 | 12.367 | IRK (PF01007, IPR016449): Inward rectifier potassium channel IRK_N (PF08466, IPR013673): Inward rectifier potassium channel N-terminal |
31 |
KCNJ4 | interactor | 6 | 0.667 | 2.200 | IRK (PF01007, IPR016449): Inward rectifier potassium channel IRK_N (PF08466, IPR013673): Inward rectifier potassium channel N-terminal |
32 |
KIF26B | interactor | 5 | 0.600 | 27.014 | Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain Microtub_bd (PF16796, IPR031852): Microtubule binding |
33 |
LIN7A | interactor | 6 | 0.667 | 2.900 | DUF932 (PF06067, IPR026325): Domain of unknown function (DUF932) L27 (PF02828, IPR014775, SM00569): L27 domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) |
34 |
LIN7B | interactor | 6 | 0.733 | 1.900 | L27 (PF02828, IPR014775, SM00569): L27 domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) |
35 |
LIN7C | interactor | 14 | 0.275 | 74.252 | His_Phos_2 (PF00328, IPR000560): Histidine phosphatase superfamily (branch 2) L27 (PF02828, IPR014775, SM00569): L27 domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) |
36 |
MARS | oncoprotein | 3 | 0.667 | 0.786 | Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA DUF16 (PF01519, IPR002862): Protein of unknown function DUF16 GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain tRNA-synt_1g (PF09334, IPR015413): tRNA synthetases class I (M) WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain GST_N_2 (PF13409, IPR004045): Glutathione S-transferase, N-terminal domain |
37 |
MLLT6 | oncoprotein | 2 | 1.000 | 0 | DUF572 (PF04502, IPR007590): Family of unknown function (DUF572) HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper SpoIIIAH (PF12685, IPR024232): SpoIIIAH-like protein zf-HC5HC2H (PF13771): PHD-like zinc-binding domain PHD_2 (PF13831): PHD-finger zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain SOBP (PF15279, IPR026092): Sine oculis-binding protein SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2 |
38 |
MYBPHL | interactor | 1 | 0 | 0 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain |
39 |
NEDD1 | interactor | 3 | 1.000 | 0 | NRBF2 (PF08961, IPR015056): Nuclear receptor-binding factor 2, autophagy regulator eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A FliM (PF02154, IPR001689): Flagellar motor switch protein FliM WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Mto2_bdg (PF12808, IPR024545): Micro-tubular organiser Mto1 C-term Mto2-binding region ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
40 |
NEDD4 | suppressor | 6 | 0.200 | 20.900 | Rota_NS26 (PF01525, IPR002512): Rotavirus NS26 WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
41 |
NTRK1 | oncoprotein | 16 | 0.171 | 133.569 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
42 |
P2RX7 | oncoprotein | 1 | 0 | 0 | Keratin_matx (PF04579, IPR007659): Keratin, high-sulphur matrix protein P2X_receptor (PF00864, IPR001429): ATP P2X receptor |
43 |
PARK2 | suppressor | 6 | 0.500 | 4.900 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
44 |
PCBP2 | protein found in more fusions | 5 | 0.833 | 0.786 | Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein KH_2 (PF07650, IPR004044): KH domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
45 |
PCM1 | oncoprotein | 4 | 0.667 | 2.800 | FliD_N (PF02465, IPR003481): Flagellar hook-associated protein 2 N-terminus FUSC (PF04632, IPR006726): Fusaric acid resistance protein family IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family RseA_C (PF03873, IPR005573): Anti sigma-E protein RseA, C-terminal domain TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein V_ATPase_I (PF01496, IPR002490): V-type ATPase 116kDa subunit family AAA_23 (PF13476): AAA domain zf-C4pol (PF14260, IPR025687): C4-type zinc-finger of DNA polymerase delta PCM1_C (PF15717, IPR031446): Pericentriolar material 1 C terminus DUF4829 (PF16111, IPR032256): Domain of unknown function (DUF4829) |
46 |
PLK2 | suppressor | 2 | 0 | 18.890 | Pkinase (PF00069, IPR000719): Protein kinase domain POLO_box (PF00659, IPR000959): POLO box duplicated region G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor |
47 |
PPM1B | interactor | 1 | 0 | 0 | PP2C (PF00481, IPR001932): Protein phosphatase 2C PP2C_C (PF07830, IPR012911, SM00332): Protein serine/threonine phosphatase 2C, C-terminal domain |
48 |
PPP4R3A | interactor | 2 | 1.000 | 0 | Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) SMK-1 (PF04802, IPR006887): Component of IIS longevity pathway SMK-1 WH1 (PF00568, IPR000697, SM00461): WH1 domain DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611) |
49 |
PRKD2 | interactor | 2 | 1.000 | 0 | ABC1 (PF03109, IPR004147): ABC1 family Pkinase (PF00069, IPR000719): Protein kinase domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
50 |
PTGS2 | oncoprotein | 3 | 1.000 | 0 | An_peroxidase (PF03098, IPR002007): Animal haem peroxidase EGF (PF00008, IPR000742, SM00181): EGF-like domain |
51 |
RPH3A | interactor | 2 | 1.000 | 0 | C2 (PF00168, IPR000008, SM00239): C2 domain OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger |
52 |
SDC1 | oncoprotein | 1 | 0 | 0 | Herpes_TAF50 (PF03326, IPR004998): Herpesvirus transcription activation factor (transactivator) Syndecan (PF01034, IPR027789): Syndecan domain DUF3592 (PF12158, IPR021994): Protein of unknown function (DUF3592) AJAP1_PANP_C (PF15298, IPR029198): AJAP1/PANP C-terminus |
53 |
SDC2 | protein found in more fusions | 3 | 1.000 | 0 | Glycophorin_A (PF01102, IPR001195): Glycophorin A Syndecan (PF01034, IPR027789): Syndecan domain DUF3275 (PF11679, IPR021693): Protein of unknown function (DUF3275) |
54 |
SH2D4A | interactor | 1 | 0 | 0 | Cytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal SH2 (PF00017, IPR000980, SM00252): SH2 domain DUF2039 (PF10217, IPR019351): Uncharacterized conserved protein (DUF2039) |
55 |
SLC16A6 | interactor | 2 | 1.000 | 0 | CBM_10 (PF02013, IPR002883, SM01064): Cellulose or protein binding domain MFS_1 (PF07690, IPR011701): Major Facilitator Superfamily |
56 |
SNTB2 | interactor | 4 | 0.667 | 2.067 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) PH (PF00169, IPR001849, SM00233): PH domain |
57 |
SPATA2 | interactor | 5 | 0.600 | 4.500 | zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger |
58 |
SRPK2 | oncoprotein | 3 | 1.000 | 0 | DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Pkinase (PF00069, IPR000719): Protein kinase domain S-antigen (PF05756, IPR008825): S-antigen protein DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) |
59 |
TBR1 | interactor | 2 | 1.000 | 0 | T-box (PF00907, IPR001699, SM00425): T-box T-box_assoc (PF16176, IPR032385): T-box transcription factor-associated |
60 |
TMEM17 | interactor | 7 | 0.381 | 102.833 | Transmemb_17 (PF09799, IPR019184): Predicted membrane protein DUF3043 (PF11241, IPR021403): Protein of unknown function (DUF3043) |
61 |
TMEM216 | interactor | 3 | 0.333 | 14.833 | Transmemb_17 (PF09799, IPR019184): Predicted membrane protein |
62 |
TRIM22 | interactor | 2 | 0 | 0 | SPRY (PF00622, IPR003877, SM00449): SPRY domain YojJ (PF10372, IPR019457): Bacterial membrane-spanning protein N-terminus zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger UBZ_FAAP20 (PF15750, IPR031490): Ubiquitin-binding zinc-finger CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour |
63 |
TRIM26 | interactor | 3 | 1.000 | 0 | Nop14 (PF04147, IPR007276): Nop14-like family SPRY (PF00622, IPR003877, SM00449): SPRY domain IFT57 (PF10498, IPR019530): Intra-flagellar transport protein 57 zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING |
64 |
TSPYL2 | interactor | 2 | 1.000 | 0 | Rtf2 (PF04641, IPR027799): Rtf2 RING-finger NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP) MAP17 (PF15807, IPR031627): Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 C_Hendra (PF16821, IPR031812): C protein from hendra and measles viruses |
65 |
UIMC1 | suppressor | 3 | 1.000 | 0 | Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif |
66 |
WNT7B | interactor | 1 | 0 | 0 | wnt (PF00110, IPR005817, SM00097): wnt family |