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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins CRIM1, IFITM1 (from a repository: Sun Aug 25 14:20:53 2019)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)8
The number (and %) of the onco-proteins1 (12.50 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)10 (35.71 %)
The number (and %) of affected PPIs6 (60.00 %)
The number of possible different fusions1
PPI diameter2
PPI radiusinf
The average degree of PPI2.250
Assortativity coefficient0.5000
The network average Clustering coefficient0.438
The number (and %) of a zero Clustering coefficients4 (50.00 %)
The number (and %) of a zero Betweenness Centrality6 (75.00 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: IFITM1,CRIM1 All fusions
Proteins found in more fusions

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 IFITM1parental protein40.5006.000CD225 (PF04505, IPR007593): Interferon-induced transmembrane protein
2 CRIM1parental protein202.000Antistasin (PF02822, IPR004094): Antistasin family
Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif
VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain
IGFBP (PF00219, IPR000867, SM00121): Insulin-like growth factor binding protein
TILa (PF12714, IPR025615): TILa domain
Amnionless (PF14828): Amnionless
3 ABHD16Ainteractor100Abhydrolase_1 (PF00561, IPR000073): alpha/beta hydrolase fold
Abhydrolase_6 (PF12697, IPR000073): Alpha/beta hydrolase family
4 ATXN7interactor100DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
SCA7 (PF08313, IPR013243): SCA7, zinc-binding domain
Macoilin (PF09726, IPR019130): Transmembrane protein
DUF3505 (PF12013, IPR022698): Protein of unknown function (DUF3505)
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
5 CACNA1Ainteractor100Ca_chan_IQ (PF08763, IPR014873, SM01062): Voltage gated calcium channel IQ domain
GRP (PF07172, IPR010800): Glycine rich protein family
Ion_trans (PF00520, IPR005821): Ion transport protein
Roughex (PF06020, IPR009259): Drosophila roughex protein
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
GPHH (PF16905, IPR031649): Voltage-dependent L-type calcium channel, IQ-associated
6 CD19interactor31.0000V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
7 CD81interactor41.0000Tetraspannin (PF00335, IPR018499): Tetraspanin family
8 CR2oncoprotein31.0000C_tripleX (PF02363, IPR003341): Cysteine rich repeat
UL45 (PF05473, IPR008646): UL45 protein, carbohydrate-binding C-type lectin-like
TIL (PF01826, IPR002919): Trypsin Inhibitor like cysteine rich domain
Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat)

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