Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins SARNP, HDLBP (from a repository: Thu Feb 16 12:08:26 2017)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)116
The number (and %) of the onco-proteins35 (30.17 %)
The number (and %) of the tumor suppressors17 (14.66 %)
Total number of binary PPIs (saturation %)592 (8.88 %)
The number (and %) of affected PPIs117 (19.76 %)
The number of possible different fusions20
PPI diameter4
PPI radius2
The average degree of PPI9.483
Assortativity coefficient-0.1878
The network average Clustering coefficient0.436
The number (and %) of a zero Clustering coefficients12 (10.34 %)
The number (and %) of a zero Betweenness Centrality21 (18.10 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: HDLBP,SARNP All fusions
Proteins found in more fusions HSPB1/OBSL1 (see 1 fusions); SMAD4 (see 2 fusions); VCP (see 4 fusions); U2AF2 (see 2 fusions); VPS26A (see 1 fusions); VHL (see 1 fusions); EWSR1 (see 2 fusions); KIF11 (see 1 fusions); PRKDC (see 3 fusions); TOPBP1 (see 2 fusions); HSPB1 (see 4 fusions); CSNK2A1 (see 1 fusions); COPS5 (see 1 fusions); THOC1 (see 3 fusions); SUV39H1 (see 1 fusions); LIMK1 (see 1 fusions); KCMF1 (see 3 fusions); VPS35 (see 2 fusions); SNW1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 HDLBPparental protein700.0814848.810BMC (PF00936, IPR000249, SM00877): BMC domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
KH_4 (PF13083): KH domain
KH_5 (PF13184, IPR025249): NusA-like KH domain
SLS (PF14611, IPR032741): Mitochondrial inner-membrane-bound regulator
DUF4530 (PF15039, IPR029202): Domain of unknown function (DUF4530)
2 SARNPparental protein470.0872780.004SAP (PF02037, IPR003034, SM00513): SAP domain
HTH_Tnp_IS630 (PF01710, IPR002622): Transposase
Prok-E2_A (PF14457, IPR032865): Prokaryotic E2 family A
3 ACAA1interactor41.0000Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain
Thiolase_N (PF00108, IPR020616): Thiolase, N-terminal domain
4 ACTL6Ainteractor50.5008.251Actin (PF00022, IPR004000, SM00268): Actin
5 ADARinteractor100.42277.816dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
z-alpha (PF02295, IPR000607, SM00550): Adenosine deaminase z-alpha domain
A_deamin (PF02137, IPR002466, SM00552): Adenosine-deaminase (editase) domain
6 AKTIPinteractor100UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
7 ARRB1interactor60.46781.464Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
8 ATP6V1B2interactor50.20031.307ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
DUF2481 (PF10654, IPR018916): Protein of unknown function (DUF2481)
9 BPGMinteractor100Exc (PF07825, IPR012884): Excisionase-like protein
His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1)
10 CBX5suppressor70.26728.667Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain
11 CCDC8interactor140.295143.315Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA
12 CDC5Linteractor230.364206.932OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
13 CDK2suppressor230.346315.778Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
14 CLUHinteractor50.50010.090DUF727 (PF05303, IPR007967): Protein of unknown function (DUF727)
eIF3_p135 (PF12807): Translation initiation factor eIF3 subunit 135
CLU (PF13236, IPR025697): Clustered mitochondria
TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
CLU_N (PF15044, IPR028275): Mitochondrial function, CLU-N-term
15 COPS5protein found in more fusions270.286412.477JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
16 CSNK2A1oncoprotein150.44066.705Pkinase (PF00069, IPR000719): Protein kinase domain
17 CSNK2Binteractor90.35721.518CK_II_beta (PF01214, IPR000704, SM01085): Casein kinase II regulatory subunit
18 CSTBoncoprotein30.6672.450Cystatin (PF00031, IPR000010, SM00043): Cystatin domain
19 CYP1A1oncoprotein30.33331.946p450 (PF00067, IPR001128): Cytochrome P450
20 DDX39Ainteractor90.39340.404DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
21 DDX43oncoprotein100DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
22 DHX9oncoprotein230.356208.732DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
T2SSE (PF00437, IPR001482): Type II/IV secretion system protein
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
23 DNAJC14interactor100DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
Jiv90 (PF14901, IPR032843): Cleavage inducing molecular chaperone
24 DPP7interactor50.7006.329Peptidase_S28 (PF05577, IPR008758): Serine carboxypeptidase S28
25 DYNLL1interactor31.0000Dynein_light (PF01221, IPR001372): Dynein light chain type 1
26 EIF2Ainteractor50.50010.294Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like
eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
27 ERBB2oncoprotein40.33319.114Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
28 ESR1suppressor260.293394.234Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
29 EWSR1oncoprotein200.333173.335RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
30 FAM46Ainteractor30.33332.131NTP_transf_7 (PF07984, IPR012937, SM01153): Nucleotidyltransferase
31 FAUinteractor40.33317.404Ribosomal_S30 (PF04758, IPR006846): Ribosomal protein S30
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
32 FN1oncoprotein240.156385.385fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
33 FUSsuppressor210.343215.075Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Limkain-b1 (PF11608, IPR024582): Limkain b1
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
34 GLMNoncoprotein21.0000Kinetochor_Ybp2 (PF08568, IPR013877): Uncharacterised protein family, YAP/Alf4/glomulin
35 HSPB1oncoprotein170.350133.831HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
36 HSPD1suppressor180.386122.197Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
37 IKBKGinteractor70.26734.848CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725)
NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO
LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
38 KCMF1oncoprotein70.4008.545zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
zf-LITAF-like (PF10601, IPR006629, SM00714): LITAF-like zinc ribbon domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
Di19_C (PF14571, IPR027935): Stress-induced protein Di19, C-terminal
Ntox28 (PF15605, IPR028948): Bacterial toxin 28
39 KIF11protein found in more fusions60.7004.516Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2
DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
Gag_p17 (PF00540, IPR000071): gag gene protein p17 (matrix protein)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
DUF3510 (PF12022, IPR024603): Domain of unknown function (DUF3510)
Microtub_bind (PF13931, IPR025901): Kinesin-associated microtubule-binding
40 LGR4interactor60.4009.7447tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
41 LIMK1oncoprotein3014.518LIM (PF00412, IPR001781, SM00132): LIM domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
42 MAGEA6interactor100MAGE (PF01454, IPR002190): MAGE family
MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
43 MLH1suppressor70.42947.505DNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain
HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Mlh1_C (PF16413, IPR032189): DNA mismatch repair protein Mlh1 C-terminus
44 MPLKIPinteractor30.6670.619MPLKIP (PF15502, IPR028265): M-phase-specific PLK1-interacting protein
45 MPP1oncoprotein21.0000PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
SH3_2 (PF07653, IPR011511): Variant SH3 domain
Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
P33MONOX (PF15302, IPR026759): P33 mono-oxygenase
46 MRPL14interactor21.0000Ribosomal_L14 (PF00238, IPR000218): Ribosomal protein L14p/L23e
RTT107_BRCT_6 (PF16771, IPR031906): Regulator of Ty1 transposition protein 107 BRCT domain
47 MRPS31interactor21.0000MRP-S31 (PF15433, IPR026299): Mitochondrial 28S ribosomal protein S31
48 MRRFinteractor31.0000RRF (PF01765, IPR023584): Ribosome recycling factor
YtxH (PF12732, IPR024623): YtxH-like protein
49 NABP2interactor31.0000tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
50 NTRK1oncoprotein470.1401510.458I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
51 OBSL1protein found in more fusions260.247385.249BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
52 PFKFB2interactor30.6670.5056PF2K (PF01591, IPR013079): 6-phosphofructo-2-kinase
His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1)
53 PLAURoncoprotein100Toxin_1 (PF00087, IPR003571): Snake toxin
UPAR_LY6 (PF00021, IPR001526): u-PAR/Ly-6 domain
54 PLCG1oncoprotein70.38178.988C2 (PF00168, IPR000008, SM00239): C2 domain
PH (PF00169, IPR001849, SM00233): PH domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
PI-PLC-X (PF00388, IPR000909, SM00148): Phosphatidylinositol-specific phospholipase C, X domain
PI-PLC-Y (PF00387, IPR001711, SM00149): Phosphatidylinositol-specific phospholipase C, Y domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
PH_12 (PF16457, IPR001849): Pleckstrin homology domain
55 PRKDCprotein found in more fusions210.42177.428FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
NUC194 (PF08163, IPR012582): NUC194 domain
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
56 PSMD12interactor70.6006.390Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
PCI (PF01399, IPR000717, SM00088): PCI domain
57 PTCRAoncoprotein21.0000PTCRA (PF15028, IPR027834): Pre-T-cell antigen receptor
58 RBMS1interactor100.33344.348RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
59 RIC8Ainteractor50.70017.949PUL (PF08324, IPR013535): PUL domain
Ric8 (PF10165, IPR019318): Guanine nucleotide exchange factor synembryn
60 S100A10oncoprotein3024.144S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
61 S100A11suppressor200S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
62 SAC3D1interactor51.0000SAC3_GANP (PF03399, IPR005062): SAC3/GANP family
63 SBDSoncoprotein120.273127.663SBDS (PF01172, IPR019783): Shwachman-Bodian-Diamond syndrome (SBDS) protein
SBDS_C (PF09377, IPR018978): SBDS protein C-terminal domain
64 SCARNA22interactor90.47211.639NA
65 SERPINB3oncoprotein40.5004.175Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
66 SERPINB5suppressor70.23829.671Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
67 SIRT7interactor170.287108.823DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
68 SMAD4suppressor90.17934.107MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
69 SMSinteractor50.50015.214Spermine_synth (PF01564, IPR001045): Spermine/spermidine synthase
70 SNRPCinteractor70.38127.561zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger
71 SNW1protein found in more fusions220.329145.079SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
72 SOS1oncoprotein30.66717.242Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
PH (PF00169, IPR001849, SM00233): PH domain
RasGEF (PF00617, IPR001895, SM00147): RasGEF domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif
73 SRCAPinteractor201.866AT_hook (PF02178, IPR017956, SM00384): AT hook motif
HSA (PF07529, IPR014012, SM00573): HSA
RXT2_N (PF08595, IPR013904): RXT2-like, N-terminal
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DBINO (PF13892, IPR020838): DNA-binding domain
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
74 SRPRBinteractor170.162465.174MHYT (PF03707, IPR005330): Bacterial signalling protein N terminal repeat
SRPRB (PF09439, IPR019009): Signal recognition particle receptor beta subunit
75 SRRM2interactor200.374233.889cwf21 (PF08312, IPR013170, SM01115): cwf21 domain
DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
Pap_E4 (PF02711, IPR003861): E4 protein
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
CTD (PF12815, IPR024945, SM01104): Spt5 C-terminal nonapeptide repeat binding Spt4
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
76 STX7interactor60.40011.934SNARE (PF05739, IPR000727, SM00397): SNARE domain
Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89
Syntaxin_2 (PF14523): Syntaxin-like protein
77 SUV39H1protein found in more fusions60.4007.782Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
Pre-SET (PF05033, IPR007728): Pre-SET motif
SET (PF00856, IPR001214, SM00317): SET domain
78 TAGLNsuppressor21.0000Calponin (PF00402, IPR000557): Calponin family repeat
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
79 TBL2suppressor40.5003.824eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
FdsD (PF11390, IPR021074): NADH-dependant formate dehydrogenase delta subunit FdsD
80 THOC1protein found in more fusions90.64314.174Death (PF00531, IPR000488, SM00005): Death domain
efThoc1 (PF11957, IPR021861): THO complex subunit 1 transcription elongation factor
81 THOC2interactor120.36477.175Sec62 (PF03839, IPR004728): Translocation protein Sec62
Tho2 (PF11262, IPR021418): Transcription factor/nuclear export subunit protein 2
Thoc2 (PF11732, IPR021726): Transcription- and export-related complex subunit
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
THOC2_N (PF16134, IPR032302): THO complex subunit 2 N-terminus
82 THOC7interactor70.66710.607EcoEI_R_C (PF08463, IPR013670): EcoEI R protein C-terminal
THOC7 (PF05615, IPR008501): Tho complex subunit 7
UPF0193 (PF05250, IPR007914): Uncharacterised protein family (UPF0193)
83 THY1suppressor100.22240.744ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
84 TIAL1interactor60.20019.756RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
85 TIMM44interactor60.33331.753Tim44 (PF04280, IPR007379, SM00978): Tim44-like domain
DUF4211 (PF13926, IPR025451): Domain of unknown function (DUF4211)
AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
RecG_N (PF17190): RecG N-terminal helical domain
86 TMEM171interactor21.0000TMEM171 (PF15471, IPR029173): Transmembrane protein family 171
87 TOPBP1protein found in more fusions31.0000BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
PTCB-BRCT (PF12738, IPR001357): twin BRCT domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
88 TPX2interactor4047.952Aurora-A_bind (PF09041, IPR015128): Aurora-A binding
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
DUF2259 (PF10016, IPR018725): Predicted secreted protein (DUF2259)
TPX2_importin (PF12214, IPR027330): Cell cycle regulated microtubule associated protein
zf-TFIIIC (PF12660, IPR024764): Putative zinc-finger of transcription factor IIIC complex
DUF4337 (PF14235, IPR025570): Domain of unknown function (DUF4337)
89 TTC4suppressor90.63912.694TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
90 TTKinteractor80.7141.660Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1
Pkinase (PF00069, IPR000719): Protein kinase domain
RIO1 (PF01163, IPR018934): RIO1 family
T3SS_basalb_I (PF17001, IPR012670): Type III secretion basal body protein I, YscI, HrpB, PscI
Mad3_BUB1_I_2 (PF17014, IPR031522): Putative Mad3/BUB1 like region 1 protein
91 TYRO3oncoprotein30.6671.749fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ig_3 (PF13927): Immunoglobulin domain
DUF4229 (PF14012, IPR025323): Protein of unknown function (DUF4229)
92 U2AF2protein found in more fusions170.57542.581RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
93 UBA6interactor70.42913.513ThiF (PF00899, IPR000594): ThiF family
E1_UFD (PF09358, IPR018965, SM00985): Ubiquitin fold domain
UBA_e1_thiolCys (PF10585, IPR019572): Ubiquitin-activating enzyme active site
94 UBE2Ainteractor50.5003.429UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
95 UBE2Iinteractor150.231173.952UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
96 UBE4Bsuppressor160.333400.754DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
Ufd2P_core (PF10408, IPR019474): Ubiquitin elongating factor core
U-box (PF04564, IPR003613, SM00504): U-box domain
DUF4568 (PF15132, IPR027919): Domain of unknown function (DUF4568)
97 UBL4Ainteractor110.29195.906ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
98 UPF1interactor160.41763.239UPF1_Zn_bind (PF09416, IPR018999): RNA helicase (UPF2 interacting domain)
AAA_11 (PF13086): AAA domain
AAA_12 (PF13087): AAA domain
99 VCPprotein found in more fusions230.303252.468AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
100 VDAC3interactor80.35752.964Porin_3 (PF01459, IPR027246): Eukaryotic porin
101 VHLsuppressor90.32194.285Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein
VHL_C (PF17211): VHL box domain
102 VPS25interactor61.0000ESCRT-II (PF05871, IPR008570): ESCRT-II complex subunit
103 VPS26Aprotein found in more fusions120.49174.541Vps26 (PF03643, IPR005377): Vacuolar protein sorting-associated protein 26
104 VPS29interactor80.8217.846Metallophos_2 (PF12850, IPR024654): Calcineurin-like phosphoesterase superfamily domain
105 VPS35protein found in more fusions130.51563.814FerA (PF08165, IPR012560): FerA (NUC095) domain
Vps35 (PF03635, IPR005378): Vacuolar protein sorting-associated protein 35
106 VPS36interactor90.71410.980EAP30 (PF04157, IPR007286): EAP30/Vps36 family
Vps36_ESCRT-II (PF11605, IPR021648): Vacuolar protein sorting protein 36 Vps36
107 WDR61interactor70.28656.127WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
108 WWOXsuppressor100.24443.085adh_short (PF00106, IPR002198): short chain dehydrogenase
WW (PF00397, IPR001202, SM00456): WW domain
109 XPOTinteractor40.5006.271DUF310 (PF03750, IPR010149): Protein of unknown function (DUF310)
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
110 XRCC5suppressor190.40599.141Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
Ku_PK_bind (PF08785, IPR014893): Ku C terminal domain like
111 YARSinteractor70.47630.612tRNA-synt_1b (PF00579, IPR002305): tRNA synthetases class I (W and Y)
tRNA_bind (PF01588, IPR002547): Putative tRNA binding domain
112 YBX1oncoprotein140.52733.943CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
113 ZC3H11Ainteractor110.236124.419Bul1_C (PF04426, IPR022794): Bul1 C terminus
Sec62 (PF03839, IPR004728): Translocation protein Sec62
zf-CCCH_3 (PF15663): Zinc-finger containing family
114 ZCCHC7interactor205.394zf-CCHC (PF00098, IPR001878): Zinc knuckle
DUF2318 (PF10080, IPR018758): Predicted membrane protein (DUF2318)
zf-CCHC_3 (PF13917): Zinc knuckle
115 ZNF598interactor40.33327.548Arc_trans_TRASH (PF08394, IPR013603): Archaeal TRASH domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_4 (PF13894): C2H2-type zinc finger
116 ZW10interactor30.3333.536Zw10 (PF06248, IPR009361): Centromere/kinetochore Zw10
DUF2203 (PF09969, IPR018699): Uncharacterized conserved protein (DUF2203)

B a c k    t o    T o p ⇑