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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins SPRYD7, CDADC1 (from a repository: Sat Sep 21 17:42:21 2019)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)9
The number (and %) of the onco-proteins3 (33.33 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)11 (30.56 %)
The number (and %) of affected PPIs7 (63.64 %)
The number of possible different fusions3
PPI diameter2
PPI radiusinf
The average degree of PPI1.556
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients9 (100.00 %)
The number (and %) of a zero Betweenness Centrality8 (88.89 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: CDADC1,SPRYD7 All fusions
Proteins found in more fusions VAC14 (see 1 fusions); UBC (see 7 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 CDADC1interactor000NA
2 SPRYD7parental protein7042.000SPRY (PF00622, IPR003877, SM00449): SPRY domain
3 CAMK2Boncoprotein200CaMKII_AD (PF08332, IPR013543): Calcium/calmodulin dependent protein kinase II association domain
Pkinase (PF00069, IPR000719): Protein kinase domain
4 HAUS7interactor100M3 (PF09213, IPR015296): M3
Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
5 NYXinteractor100LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
6 PDZD3interactor100PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
7 TRIP13interactor200AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
8 UBCprotein found in more fusions200ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
9 VAC14oncoprotein200TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain
HEAT (PF02985, IPR000357): HEAT repeat
Vac14_Fig4_bd (PF11916, IPR021841): Vacuolar protein 14 C-terminal Fig4p binding
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region

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